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1 of UPF1 to release RNA upon ATP binding and hydrolysis.
2 longed protein stability against proteolytic hydrolysis.
3 orm organic sulfur that is resistant to acid hydrolysis.
4 the target C-N coupling product upon in situ hydrolysis.
5 kinetic steps are accelerated by faster ATP hydrolysis.
6 erone "helper" proteins, and ATP binding and hydrolysis.
7 mation on ATPase domain architecture and ATP hydrolysis.
8 e before conversion to the derived ketone by hydrolysis.
9 and this cycle is linked to GTP binding and hydrolysis.
10 d convert into benzoic acids due to C-F bond hydrolysis.
11 iotics is via their beta-lactamase-catalyzed hydrolysis.
12 ng catalysis and how they are coupled to ATP hydrolysis.
13 y of protein synthesis at the expense of GTP hydrolysis.
14 d 70S ribosomes in vitro, independent of GTP hydrolysis.
15 es and the cytosolic headpiece mediating ATP hydrolysis.
16 steadily increased with increasing degree of hydrolysis.
17 the allosteric transition that triggers ATP hydrolysis.
18 y of prepared compounds toward acid-promoted hydrolysis.
19 by HPLC coupled to tandem MS after enzymatic hydrolysis.
20 s the levels of cellular dNTPs through their hydrolysis.
21 l cores, whose formation requires MukBEF ATP hydrolysis.
22 , and eight presented 72.74-84.54% of starch hydrolysis.
23 nhibited heparanase and was resistant toward hydrolysis.
24 s host-pathogen lipid imaging following acid hydrolysis.
25 aining mycobacterial GyrB are limited by ATP hydrolysis.
26 -anticodon interactions before and after GTP hydrolysis.
27 f receptor subtypes, and the dynamics of ACh hydrolysis.
28 ine, which results in unproductive glutamine hydrolysis.
29 hey showed faster (higher k) in vitro starch hydrolysis (0.0140 vs 0.0050) with lower estimated glyce
30 study of lactose digestion showed levels of hydrolysis (82.8%) at 0.2 mg*mL(-1) and the highest hydr
32 oteins exhibit conserved GTP-binding and GTP-hydrolysis activities, and function in maintaining overa
33 atient, both have gain-of-function Rad50 ATP hydrolysis activity that results not from faster associa
34 enome replication, RNA-binding affinity, ATP hydrolysis activity, and helicase-mediated unwinding act
36 prised of a cytoplasmic V(1) complex for ATP hydrolysis and a membrane-embedded V(o) complex for prot
38 motifs that were linked to enzyme-catalyzed hydrolysis and are therefore candidates for incorporatio
40 ylation abolishes the K(+)-dependence of ATP hydrolysis and blocks the catalytic cycle after formatio
41 requires fuel consumption in the form of ATP hydrolysis and coordination of the catalytic cycles betw
42 e results challenge sequential models of ATP hydrolysis and coupled mechanical work by ClpAP and prov
45 expression of specific genes involved in TAG hydrolysis and fatty acid oxidation, and that PA relieve
48 ecies relevant to Br(-) oxidation, and Cl(2) hydrolysis and formation reactions (Cl2 + H2O + A- k-4k4
49 ntein fusion approach suffers from premature hydrolysis and low compatibility with denatured conditio
54 an energy-consuming futile cycle between TG hydrolysis and resynthesis, leading to inhibition of mTO
55 ione transport activity, suggesting that ATP hydrolysis and substrate transport by Atm1 may involve a
57 WS) and Lotus stem (LS) by using mild alkali hydrolysis and ultra-sonication process has been present
58 P-loop NTPase fold enzymes that catalyze ATP-hydrolysis and utilize its free energy for a staggering
60 molecular machines by coupling ATP binding, hydrolysis, and phosphate release to translocation of di
61 opose a model of how substrate cleavage, ATP hydrolysis, and substrate translocation are coordinated
62 otor rotation, negative cooperativity in ATP hydrolysis, and the energetic requirement for at least 1
63 a subunits in G-proteins, accelerate the GTP hydrolysis, and thereby rapidly dampen GPCR signaling.
64 ues play in regulating ribosome binding, GTP hydrolysis, and translation initiation both in vitro and
67 the S-nitrosylation assay, 5.8 in the NAD(+) hydrolysis assay, and 6.8 in the enzymatic ADP-ribosyltr
69 nge tested had a minor effect on bound-forms hydrolysis, being both free and bound forms equally affe
71 on and dissociation steps do not require ATP hydrolysis, but subsequent forward and reverse kinetic s
73 quence of the ability of ClpS to repress ATP hydrolysis by ClpA, but several lines of evidence show t
76 red for HSP70's role: we have found that ATP hydrolysis by HSP70, the nucleotide exchange activity of
77 -5 tails decrease microtubule-stimulated ATP-hydrolysis by specifically engaging motor domains in the
79 to restart elongation via stimulation of RNA hydrolysis by the active centre of RNA polymerase (RNAP)
82 coated pits is spatially segregated from its hydrolysis by the PI(3,4)P(2)-specific inositol polyphos
83 rkably, 5' end recognition and pyrophosphate hydrolysis by the PPsome complex also contribute to mRNA
84 lied for real-time monitoring of beta-casein hydrolysis by trypsin at various conditions for the firs
85 in a closed conformation and stimulates ATP hydrolysis by XPB while AfBax1 maintains AfXPB in the op
90 ction of ribosomes from Fe(2+)-mediated rRNA hydrolysis correlates with the restoration of cell viabi
93 enzymatic models were fitted with degree of hydrolysis (d(h)) profiles to provide kinetic and mechan
94 ntestinal digestion showed a 4.2-fold higher hydrolysis degree in the protein concentrate than the fl
96 priming (recovery stroke) while slowing ATP hydrolysis, demonstrating that it uncouples these two st
97 roscopy was applied to predict the degree of hydrolysis (DH%) and weight-average molecular weight (M(
98 s food formulation effects on the degrees of hydrolysis (DH) of both proteins and lipids throughout i
99 that can potentially influence the degree of hydrolysis (DH), equivalent umami concentration (EUC), a
101 imulates the adenosine 5'-triphosphate (ATP) hydrolysis-driven motor activity of DNA2 involved in the
102 her bacterial diversity in cheese on protein hydrolysis during simulated human digestion, Raclette-ty
103 controlled precipitation and to inhibit urea hydrolysis during storage until further treatment in mor
104 ) between 1.15 and 0.59 mg/mL), although the hydrolysis enhanced the bioactivity of HQE (p = 0.014).
108 antification method based on strong alkaline hydrolysis followed by High Performance Anion Exchange C
111 brane-embedded enzymes use the energy of ATP hydrolysis for transmembrane transport of a wide range o
112 in SO, SI showed slightly higher or similar hydrolysis (free fatty acids and diacylglycerols), simil
113 ime during thermal treatment, and decoupling hydrolysis from fibril self-assembly helped to identify
117 al a function for INPP4-mediated PI(3,4)P(2) hydrolysis in local regulation of growth factor and nutr
118 (Phi(u)), low susceptibility to spontaneous hydrolysis in the dark, and good aqueous solubility.
120 (OPA) intermediate can proceed via alkaline hydrolysis in the presence of D(2) O to provide alpha-de
121 mismatch recognition, ATP converts MutS to a hydrolysis-independent, diffusive mobile clamp that no l
123 mulations of 1) adenosine triphosphate (ATP) hydrolysis into adenosine monophosphate (AMP) and 2) AMP
124 te alanine mutants indicates that carbapenem hydrolysis is a concerted effort involving multiple resi
125 Cl(2) formation are acid-catalyzed and Cl(2) hydrolysis is base-catalyzed, but the impact of carbonat
126 uble in these conditions, confirming the HHM hydrolysis is caused by a heterogeneous reaction of the
127 taken up in a 'selfish' mode, where initial hydrolysis is coupled to transport into the periplasm, s
129 DQ-OVA, a substrate for proteases which upon hydrolysis is fluorescent) was compared in vitro and the
137 tch again instead of bypassing it; thus, ATP hydrolysis licenses the MutS mobile clamp to rebind the
138 MR kinetic experiments constrain the 1,2-IHN hydrolysis lifetime to less than 10 s in deuterium oxide
139 mutant enzyme exhibits decreased ceftazidime hydrolysis, lower thermostability, and decreased protein
141 d water volume, we show that condensed-phase hydrolysis of 1,2-IHN can account for this loss process.
145 ographic product quantification, compared to hydrolysis of amylose and amylopectin estimated using 3,
146 velopment of a model in which the sequential hydrolysis of ATP is coupled to motions of ClpX loops th
148 mplexes catalyzing the bicarbonate-dependent hydrolysis of ATP, which is the first half-reaction cata
150 tained higher levels of terpenes (indicating hydrolysis of bound forms) and fermentation-derived vola
155 Here, we investigated whether CD73-mediated hydrolysis of extracellular ATP (eATP) could affect inte
156 nzoic acid) allosterically activates ERAP1's hydrolysis of fluorogenic and chromogenic amino acid sub
157 identified that a DspB mutant with improved hydrolysis of fully acetylated PNAG oligosaccharides cor
160 pression) in the tubulin dimer following the hydrolysis of GTP have been suggested to generate stress
161 ese changes were attributed to increased net hydrolysis of IHTG and partitioning of the resulting fat
163 lks, including breast milk, during enzymatic hydrolysis of lactose by supplemental beta-galactosidase
165 in and punicalagin were weaker inhibitors of hydrolysis of maltoheptaoside (<50% inhibition) than amy
167 onstrate that the MHETase lid is crucial for hydrolysis of MHET and, furthermore, that MHETase does n
168 ere show that MTH1 efficiently catalyzes the hydrolysis of N6-methyl-dATP to N6-methyl-dAMP and furth
169 hesized and characterized the photolysis and hydrolysis of NB moieties containing different labile bo
170 similar in nature to those for the alkaline hydrolysis of neutral arylsulfonate monoesters or charge
172 h the average intracellular pH minimizes the hydrolysis of nucleotides by slowing their reaction with
175 demonstrated that 60% sorbitol could retard hydrolysis of OVT completely for a period of time during
176 Soil extracellular phosphatases catalyze the hydrolysis of P from soil organic matter, an important a
182 the major structural levers to modulate the hydrolysis of proteins (final DH between 51.7 and 58.3%)
185 , we demonstrate that DXO also catalyzes the hydrolysis of RNAs bearing a 5'-hydroxyl group (5'-OH RN
187 d; their increase could be mainly due to the hydrolysis of sucrose, which decreased in the same perio
190 idenced that prolonged heat treatment caused hydrolysis of the attached polysaccharide and consequent
194 The generation of nascent-HBr from the slow hydrolysis of the dispersed catalyst, benzyl bromide, wi
205 ic fraction, after saponification and acidic hydrolysis of the samples, are extracted by solvent and
208 The Chlamydomonas reinhardtii Compromised Hydrolysis of Triacylglycerols7 (CHT7) protein has been
209 e (LPL) to GPIHBP1 focuses the intravascular hydrolysis of triglyceride-rich lipoproteins on the surf
210 nnosidase II (GMII) catalyzes the sequential hydrolysis of two mannosyl residues from GlcNAcMan(5)Glc
216 /MS methods were developed and validated for hydrolysis optimization and for quantification of eight
217 also demonstrate that mutants perturbing ATP hydrolysis or DNA cleavage in vitro impair P2 OLD-mediat
221 e nucleotide-binding-domain dimer, while ATP hydrolysis per se does not reset MRP1 to the resting sta
222 motor (BFM), ATP (adenosine-5'-triphosphate) hydrolysis probably drives both motor rotation and filam
223 trix scoring multiplex qPCR assays utilize a hydrolysis probe, providing sensitive and specific F. tu
226 ur calculations suggest that sulfate diester hydrolysis proceeds through loose transition states, wit
227 s remained mostly in the sediments after the hydrolysis process in the Flavorpro treated samples, whi
228 reduces the BN heterocyclic ring, which upon hydrolysis produces a rare example of a macrocyclic para
229 gh the transition state until release of the hydrolysis product, despite changes in ring conformation
231 ycation, oxidation and nitration and related hydrolysis products, glycation, oxidation and nitration
232 s shown that, in addition to the established hydrolysis products, the reaction of the class D nucleop
233 s adept control of Pu(IV) coordination under hydrolysis-prone conditions, provides an opportunity to
234 Powered by the energy of ATP binding and hydrolysis, protease-containing ABC transporters (PCATs)
238 ide chains and led to an increased enzymatic hydrolysis rate constant for the first stage of hydrolys
239 scription of proteolysis in terms of initial hydrolysis rate, r(0), and rate constant of hydrolysis,
240 oom phase was characterized by high external hydrolysis rates of a broad range of polysaccharides and
245 tons, the enzyme eliminates water, a reverse hydrolysis reaction, to yield the benzoxazole and avoids
250 Cellular DNA can be damaged by spontaneous hydrolysis, reactive oxygen species, aberrant cellular m
251 iration from ATP synthesis or increasing ATP hydrolysis restores NAD(+)/NADH homeostasis and prolifer
252 in either LPL or GPIHBP1 impair triglyceride hydrolysis, resulting in severe hypertriglyceridemia.
253 features in the enzyme, such as a nucleotide hydrolysis site or multiple intermediate conformations.
254 mic tail of SLC38A9 in the pre- and post-GTP hydrolysis state of RagC, which explain how SLC38A9 dest
255 ignificantly, kinking of TM6 in the post-ATP hydrolysis state stabilized by MgADPVO(4) eliminates thi
256 However, it remains unclear how binding and hydrolysis structurally alters the SL receptor to enable
257 e found that uptake by the 14A mutant is ATP hydrolysis-, substrate concentration-, and time-dependen
258 s for the kinetic analysis of peanut protein hydrolysis that lead to high reduction rate (K) of the I
261 roinitiator to protect the NCA monomers from hydrolysis through spontaneous in situ self-assembly (IS
264 ied on the flavonoid rutin to understand its hydrolysis to aglycones, antioxidant capacity and optica
265 elicases couple adenosine triphosphate (ATP) hydrolysis to conformational changes of their catalytic
266 -Cope reaction with formaldehyde followed by hydrolysis to eliminate unmask redox reporter N-alkylate
267 ers chemomechanically couple ATP binding and hydrolysis to large-scale conformational changes, ultima
269 nergy of nucleoside triphosphate binding and hydrolysis to mechanical movement along a polymer lattic
270 mechanoenzyme that uses the energy from ATP hydrolysis to physically reshape and remodel, and thus m
271 xes, cohesin, condensin, and Smc5/6, use ATP hydrolysis to power a plethora of functions requiring or
273 AAA+ protein, Skd3 (human ClpB), couples ATP hydrolysis to protein disaggregation and reactivation.
274 teases are degradation machines that use ATP hydrolysis to unfold protein substrates and translocate
278 n hull was performed by means of an alkaline hydrolysis treatment, which was optimized by the respons
281 mpounds (up to 178 mg/100 g) while the basic hydrolysis underestimates the phenolic concentration.
282 et of DspB in PNAG substrate recognition and hydrolysis using a combination of site-directed mutagene
283 cted arabinoxylan was subjected to enzymatic hydrolysis using individual xylanase, arabinofuranosidas
284 ing properties improved only until degree of hydrolysis values of 1.5% (neural endoprotease) and 1.9%
288 P < 0.05), whereas the pentapeptide epitopes hydrolysis was influenced only by the actinidin concentr
289 Using mutated human tubulin with blocked GTP hydrolysis, we demonstrate that EBs bind with high affin
290 ally reduce cephalosporin but not penicillin hydrolysis, we suggest that clavulanic acid paired with
291 w that N-trifluoromethyl amines are prone to hydrolysis, whereas N-trifluoromethyl azoles have excell
292 for uncoupling substrate reduction from ATP hydrolysis, which may provide new avenues for studying t
293 y adding a previous step including enzymatic hydrolysis with a xylanase, a functional evaluation of D
294 polysaccharide quantification based on acid hydrolysis with concomitant use of trifluoroacetic and h
295 gh SDS-PAGE analysis, an increased degree of hydrolysis with longer fermentation time was confirmed.
296 es demonstrate the recovery of free GMT upon hydrolysis, with biological activity as assessed by cyto
297 cellular homeostasis through macromolecular hydrolysis within their lumen and metabolic signaling by
298 ter in hydrolysis of seaweed increased sugar hydrolysis yield and subsequent bioethanol production.
299 eatment process was developed to improve the hydrolysis yield of brown (Laminaria digitata), green (U
300 ched or free extracellular enzymes (external hydrolysis) yield LMW products available to the wider ba