ライフサイエンスコーパス: hydrophilic domain

1 eviously, we determined the structure of the hydrophilic domain.

2 3 TM helices, and the known structure of the hydrophilic domain.

3 module that was identified previously in the hydrophilic domain.

4 terminal hydrophobic domain and a C-terminal hydrophilic domain.

5 cal conformational change within the central hydrophilic domain.

6 this effect was abrogated by deletion of two hydrophilic domains.

7 It includes a large hydrophilic domain, a single carboxyl-terminal hydrophob

8 hich lacked the first half of the N-terminal hydrophilic domain, accumulated in the Golgi apparatus d

9 mbrane spans, entailing the translocation of hydrophilic domains across the inner membrane, is still

10 l aaPGSs revealed that the carboxyl-terminal hydrophilic domain alone is sufficient for aminoacylphos

11 nction that is composed of an amino-terminal hydrophilic domain and a carboxyl-terminal hydrophobic d

12 possess an anesthetic-binding cavity in its hydrophilic domain and a cation channel in its hydrophob

13 h indicate the heterogeneous distribution of hydrophilic domains and hydrophobic domains on the parti

14 ographically the orientation of the adjacent hydrophilic domains and the determinants of transport sp

15 allowed membrane-embedded domains to become hydrophilic domains and vice versa.

16 ydrophilic apyrase domain, one COOH-terminal hydrophilic domain, and two hydrophobic stretches in the

17 y, and several regions within the N-terminal hydrophilic domain are essential for biological competen

18 All hydrophilic domains are in the cytoplasm, including the

19 20, an integral inner membrane protein whose hydrophilic domains are located in the intermembrane spa

20 out-Cin orientation, with the adjacent large hydrophilic domain being exposed to the cytoplasm.

21 firm the intracellular topology of the large hydrophilic domain between the proposed sixth and sevent

22 f the Golgi apparatus, and the COOH-terminal hydrophilic domain binds to the cytoplasmic face of the

23 The thicknesses of the hydrophobic and hydrophilic domains changed to the same magnitude when t

24 s the bilayer six times with the bulk of its hydrophilic domains disposed toward the cytoplasm.

25 terminal hydrophobic domain and a C-terminal hydrophilic domain; expression of the latter domain fuse

26 membrane alpha-helix topology with two large hydrophilic domains extending on the stromal and lumenal

27 e structures showed separate hydrophobic and hydrophilic domains formed within the Nafion layer when

28 Results of our current studies establish the hydrophilic domain (HD) of Sulf enzymes as an essential

29 the specific interaction between the unique hydrophilic domain (HD) of the human cell-surface sulfat

30 1a from the Virginia strain revealed a large hydrophilic domain (HD), extending from amino acids (aa)

31 nding domain, nine cohesin domains, and four hydrophilic domains (HLDs).

32 binding domain (E1DBD) contains three major hydrophilic domains (HR1, amino acids 179-191; HR2, amin

33 Our findings suggest that hydrophilic domain II may be involved in cell entry.

34 tagenesis to replace selected amino acids in hydrophilic domain II of the structural fimbrial subunit

35 ctor domain, thus implicating the N-terminal hydrophilic domain in a regulatory role.

36 er membrane protein that appears to have two hydrophilic domains in the matrix, flanking a central hy

37 ox reaction of complex I is catalyzed in the hydrophilic domain; it comprises NADH oxidation by a fla

38 s from the putatively cytoplasmic C-terminal hydrophilic domain left transport function unimpaired, b

39 due primarily to variations in the sizes of hydrophilic domains localized to the N termini, the C te

40 ng the interface between the hydrophobic and hydrophilic domains makes a larger contribution in the s

41 ting of full-length RodX, but the N-terminal hydrophilic domain no longer translocated.

42 regions of NS2B, leaving only the conserved hydrophilic domain of 40 amino acids, resulted in highly

43 he Saccharomyces FKS polypeptides is a large hydrophilic domain of 578 amino acids that is predicted

44 xin family proteins in possessing a sizeable hydrophilic domain of 63 amino acids that is C-terminal

45 18 amino acid residue peptide derived from a hydrophilic domain of a cloned platelet type I collagen

46 g the tyrosine residue at position 10 in the hydrophilic domain of Abeta(1-42) with tryptophan.

47 ane spans (approximately 440 residues) and a hydrophilic domain of approximately 360 residues at the

48 on analysis demonstrated that the N-terminal hydrophilic domain of CAML (amino acids (aa) 1-189) medi

49 Recently, a first atomic structure of the hydrophilic domain of complex I from Thermus thermophilu

50 e arrangement of iron-sulfur clusters in the hydrophilic domain of complex I from Thermus thermophilu

51 g domain decreased electron leakage from the hydrophilic domain of NQR.

52 e protease domain (NS3-pro) and requires the hydrophilic domain of NS2B (NS2BH) for activation.

53 domain (NS3pro) that requires the conserved hydrophilic domain of NS2B for protease activity in clea

54 tant ndNS2B-NS3(Pro) in which the functional hydrophilic domain of NS2B was deleted, were analyzed us

55 envelope, whereas additional regions in the hydrophilic domain of otefin are required for its effici

56 tely 25 kDa and lacks most of the N-terminal hydrophilic domain of other SCAMPs.

57 Notably, the carboxyl-terminal hydrophilic domain of PEN-2 was dispensable for promotin

58 the purified delta subunit and the isolated hydrophilic domain of the b subunit (bsol) has been stud

59 acid residues were deleted from the central hydrophilic domain of the exchanger remained sensitive t

60 egions in the cytosolically disposed central hydrophilic domain of the NCX protein.

61 ence that indicates that the large (>90-kDa) hydrophilic domain of Tic110 is localized within the chl

62 btained 10 days after infection and that the hydrophilic domain of TprK is a target of opsonic antibo

63 ogeneity in the central portions of the TprK hydrophilic domains of 14 treponemal isolates.

64 of CD1-restricted TCRs and suggest that the hydrophilic domains of a lipid Ag can form a combinatori

65 nds were selectively incorporated within the hydrophilic domains of a phase-separated (polynorbornene

66 o-length" cross-linking reagent and isolated hydrophilic domains of complex I from Escherichia coli a

67 d, based on the sequences of three predicted hydrophilic domains of IL-16 potentially presented in ex

68 cterization of the relative sidedness of the hydrophilic domains of membrane proteins.

69 eal that conserved amino acid regions in the hydrophilic domains of QSulf1 and QSulf2 have multiple f

70 etions of 10 amino acids in each of the four hydrophilic domains of the protein and found that all fo

71 The hydrophobic, but not the hydrophilic, domain of plant CHX is remarkably similar t

72 d and the differentiation of hydrophobic and hydrophilic domains on the surface.

73 The crystal structure of the hydrophilic domain (peripheral arm) of complex I from Th

74 The hydrophilic domain (peripheral arm) of the proton-transl

75 We have determined the structure of its hydrophilic domain previously.

76 ale, being significantly attenuated when the hydrophilic domains reach a size of 2 nm.

77 ossess an additional, internal 88 amino acid hydrophilic domain, rich in glutamic acid and lysine.

78 mask to produce periodic arrays of patterned hydrophilic domains separated from hydrophobic surroundi

79 as two membrane-spanning domains and a large hydrophilic domain that extends along one side of the en

80 gment near its N terminus and an 88-residue, hydrophilic domain that extends into the periplasm.

81 ve transmembrane domains surrounding a short hydrophilic domain that is presumably cytoplasmic.

82 no acid sequence and possess long N-terminal hydrophilic domains that bear typical (DE)XXXL(LI) endos

83 multispanning membrane protein without large hydrophilic domains that is very tightly associated with

84 n along the interface within the hydrophobic-hydrophilic domains, the exchange of protons between dif

85 to the inner membrane and translocates their hydrophilic domains through the membrane is poorly under

86 generated an R-Ras molecule with an inserted hydrophilic domain to circumvent membrane rigidity cause

87 e residues predicted to lie in intracellular hydrophilic domains were reactive but not accessible in

88 cur in the intact enzyme and in the isolated hydrophilic domain (which can be used for crystallograph

89 omain based on a synthetic ion channel and a hydrophilic domain with designed cavities for binding th