ライフサイエンスコーパス: hydroxy

1 ielding the corresponding 2-phosphorylated 1-hydroxy-1,2,3,4-tetrahydronaphthalenes in excellent yiel

2 e and aspartate analogues designed using the hydroxy-1,2,3-triazole moiety as a bioisostere for the d

3 Aspartate analogue 8 with the hydroxy-1,2,3-triazole moiety directly attached to glyci

4 ,N',N'-tetrakis(2-(l-ethylbenzimidazolyl))-2-hydroxy-1,3-diaminopropane; DMF = dimethylformamide) wit

5 alyse the antiradical capacity of juglone (5-hydroxy-1,4,-naphthoquinone).

6 thermogravimetry, it was demonstrated that 5-hydroxy-1,4-naphthalenedione has high thermal stability

7 alcones were coupled with 1/2-naphthols or 2-hydroxy-1,4-naphthoquinone using Ru(bpy)(3)(PF(6))(2) as

8 lieved to proceed via an in situ generated 2-hydroxy-1-(pyridin-2-yl)indolin-3-one as the key reactio

9 orinated version of the ceramide analog N-(3-hydroxy-1-hydroxymethyl-3-phenylpropyl) dodecanamide, wa

10 the reaction between readily available 2-(3-hydroxy-1-yn-1-yl)phenols, CO, and oxygen carried out in

11 Although chemometric analysis showed 9-hydroxy-10,12-octadecadienoic acid was slightly increase

12 A (7), 30-hydroxykuroshine A (8), and 3beta-hydroxy-11-deketo-kuroshine B (9), was isolated from the

13 temic toxicities, herein we synthesized 2-(4-hydroxy-1H-indol-3-yl)-1H-imidazol-4-yl)(3,4,5-trimethox

14 hydroxypyrazole ribonucleotide (CHPR) from 4-hydroxy-1H-pyrazole-3,5-dicarboxylic acid and phosphorib

15 noassay paper sensor for quantifying urine 8-hydroxy-2'-deoxyguanosine (8-OHdG) as a biomarker for di

16 NP-based substrate (Gel-BSA-OHG) to adhere 8-hydroxy-2'-deoxyguanosine (8-OHdG) to the polystyrene pl

17 al women and their levels of OS biomarkers 8-hydroxy-2'-deoxyguanosine (8-OHdG), superoxide dismutase

18 ed lipocalin [NGAL]) and oxidative stress (8-hydroxy-2'-deoxyguanosine [8-OHdG] and F2-isoprostane).

19 uanosine (OxGua) concentrations, including 8-hydroxy-2'-deoxyguanosine, were assessed in 8,793 older

20 itive to the I (Ks) blocker (3R,4S)-(+)-N-[3-hydroxy-2,2-dimethyl-6-(4,4,4-trifluorobutoxy) chroman-4

21 ydrides, and acrylic acid derivatives with 4-hydroxy-2-alkynoates have been disclosed.

22 atile cyclohexanol (23 mV; 2575th, 19-38), 3-hydroxy-2-butanone (16 mV, 9-26), 3-methylbutanal (20 mV

23 s released significantly higher amounts of 3-hydroxy-2-butanone (acetoin), 6-methyl-5-hepten-2-one (s

24 The condensation reaction between 6-hydroxy-2-cyanobenzothiazole (CBT) and cysteine has been

25 ites (2-DAMP glucuronide, didesethyl PM, and hydroxy-2-DAMP glucuronide) were tentatively identified

26 Modification in oxidative stress (i.e., 8-hydroxy-2-deoxyguanosine) prior to sleep onset was corre

27 The formation of malondialdehyde (MDA), 4-hydroxy-2-hexenal (HHE), 4-hydroxy-2-nonenal (HNE), and

28 londialdehyde, 4-hydroxynonenal (HNE), and 4-hydroxy-2-hexenal protein adduct levels.

29 d in isoprenoid and thiamine biosynthesis, 1-hydroxy-2-methyl-2-(E)-butenyl-4-diphosphate synthase an

30 suring its urinary metabolite, N-acetyl-S-(4-hydroxy-2-methyl-2-buten-1-yl)-l-cysteine (IPM3) in part

31 aldehyde (MDA), 4-hydroxy-2-hexenal (HHE), 4-hydroxy-2-nonenal (HNE), and 4-oxo-2-nonenal (ONE) in co

32 ROS-derived 4-hydroxy-2-nonenal induced interleukin IL-8 release from

33 o-2'-desoxyguanosine), lipid peroxidation (4-hydroxy-2-nonenal, isoprostane), inflammation (interleuk

34 ropose the (3Z,5E)-6-(3,4-dihydroxyphenyl)-4-hydroxy-2-oxohexa-3,5-dienoic acid form as the light emi

35 In particular, 4-chlorobenzyl-4-hydroxy-2-phenyl-1-thia-2,7-diazaspiro[4,4]nonane 1,1-di

36 study of the photochemical CO release from 3-hydroxy-2-phenyl-4H-chromen-4-one, a pai-extended 3-hydr

37 have predicted that the bulky diol 1,4-Bis(2-hydroxy-2-propyl)benzene, which has distant hydroxyl gro

38 chemical properties of previously reported 4-hydroxy-2-quinolone-3-carboxamides, a structural optimiz

39 -dihydroxy-28-deoxyzoanthenamine (2), 7alpha-hydroxy-28-deoxyzoanthenamine (3), 3alpha-hydroxyzoanthe

40 this study ((3-(N-butylethanimidoyl)ethyl)-4-hydroxy-2H-chromen-2-one; BHC) was previously discovered

41 ve being the lipoyl-derivative 15 and the (4-hydroxy-3,5-di-tert-butyl)benzoyl-analogue 21 which were

42 In this study, 3,3-bis(4-hydroxy-3-((E)-((4-hydroxyphenyl)imino)methyl) phenyl)is

43 nzylamine (NPS R-568) and 2-chloro-6-[(2R)-2-hydroxy-3-[(2-methyl-1-naphthalen-2-ylpropan-2-yl)amino]

44 methacrylate-based dental resins-2-bis[4-(2-hydroxy-3-methacryl-oxypropoxy)-phenyl]-propane (Bis-GMA

45 ne, aspartate, glycerol, nicotinamide, and 3-hydroxy-3-methyglutarate in the leaves of chickpea.

46 (syn- and anti-ketol diastereoisomers) and 3-hydroxy-3-methyl-2,4-nonanedione (HMND), prompted the in

47 monophosphonate derivatives of the PAg (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBP) as well

48 n capable of recognizing the microbial (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP) produc

49 Its substrate, (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate (HMBPP), is no

50 PAgs can be microbial [(E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate, HMBPP] or end

51 y the microbial-derived phosphoantigen (E)-4-hydroxy-3-methyl-but-2-enyl pyrophosphate.

52 oup 1, comprised of patients under regular 3-hydroxy-3-methyl-glutaryl-coenzyme A (HMG-CoA) reductase

53 an College of Cardiology (AHA/ACC) changed 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitor

54 unger adults met guideline indications for 3-hydroxy-3-methyl-glutaryl-coenzyme A reductase inhibitor

55 cell migration, contains an unusual 2-acyl-4-hydroxy-3-methylbutenolide in addition to the glutarimid

56 hylpiperidin-1-yl)pyrimidin-4-yl)amino)-3-(3-hydroxy-3-methylbutyl)-1-methyl-1,3-dihydro-2H-benzo[d]i

57 l) were found, of which quercetin-3-O-[4"-(3-hydroxy-3-methylglutaroyl)]-alpha-rhamnoside was found f

58 focused on the two rate-limiting enzymes: 3-hydroxy-3-methylglutaryl CoA reductase and squalene mono

59 to their cholesterol-lowering properties, 3-hydroxy-3-methylglutaryl coenzyme A reductase inhibitors

60 The 3-hydroxy-3-methylglutaryl coenzyme A synthases (HCSs) are

61 way that proceeds via an unprecedented (R)-3-hydroxy-3-methylglutaryl-CoA (HMG-CoA) stereospecific ro

62 ulation increases the protein abundance of 3-hydroxy-3-methylglutaryl-CoA reductase (HMGCR) and ATP-c

63 atory element-binding protein 1 (Srebp1c), 3-hydroxy-3-methylglutaryl-CoA reductase (Hmgcr), and cyto

64 Both 3-Hydroxy-3-Methylglutaryl-CoA Reductase and Proprotein Co

65 in Convertase Subtilisin/Kexin type 9, and 3-Hydroxy-3-Methylglutaryl-CoA Reductase single nucleotide

66 HCS cassette, comprising a ketosynthase, a 3-hydroxy-3-methylglutaryl-CoA synthase, a dehydratase, a

67 small intestine, the expression of Hmgcs2 (3-hydroxy-3-methylglutaryl-CoA synthetase 2), the gene enc

68 and compare those to genetic inhibition of 3-hydroxy-3-methylglutaryl-coenzyme A reductase (HMGCR).

69 ad to discontinuation or non-initiation of 3-hydroxy-3-methylglutaryl-coenzyme A reductase therapy in

70 to treat hypercholesterolemia, inhibit the 3-hydroxy-3-methylglutaryl-coenzyme A reductase, the rate-

71 identification of two new hydroxy ketones, 2-hydroxy-3-methylnonan-4-one (syn- and anti-ketol diaster

72 pounds were identified: two new compounds, 2-hydroxy-3-methylpentanoic-2-O-beta-glucopyranoside (H3MP

73 recognize a common foreign Ag (the hapten 4-hydroxy-3-nitrophenylacetyl) but differ in L chain expre

74 enzopyrones to a new series of biorelevant 2-hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxamides and 2

75 o-2,3-dihydrobenzofuran-2-carboxamides and 2-hydroxy-3-oxo-2,3-dihydrobenzofuran-2-carboxylates using

76 from the D-ring of the steroid metabolite 17-hydroxy-3-oxo-4-pregnene-20-carboxyl-CoA (17-HOPC-CoA).

77 SHE afford flavanone, 2'-hydroxychalcone, 2'-hydroxy-3-phenylpropionate, and two new compounds, namel

78 2-carboxylate (przNH(2)), and 1,2-dimethyl-3-hydroxy-4(1 H)-pyridinonate (dhp), was studied.

79 to the identification of the lead compound 2-hydroxy-4-((4-(naphthalen-2-yl)thiazol-2-yl)amino)benzoi

80 broblast growth factor 19 (FGF19) and 7alpha-hydroxy-4-cholesten-3-one (C4) concentrations were measu

81 dary BA and FGF19 levels and reduced 7-alpha-hydroxy-4-cholesten-3-one (C4) levels (P < 0.05 for all)

82 cantly greater decreases in levels of 7alpha-hydroxy-4-cholesten-3-one, bile acids, alanine and aspar

83 nd cT1, but not in liver fat content, 7alpha-hydroxy-4-cholesten-3-one, or ALT, were observed in hist

84 ining a fluorescent unnatural amino acid, (7-hydroxy-4-coumarin-yl) ethylglycine, which provides a si

85 n of a fluorescent un-natural amino acid, (7-hydroxy-4-coumarin-yl)-ethylglycine, using orthogonal am

86 mones, Nasonia vitripennis evolved (4R,5R)-5-hydroxy-4-decanolide (RR) as an extra sex pheromone comp

87 l Nasonia species use a mixture of (4R,5S)-5-hydroxy-4-decanolide (RS) and 4-methylquinazoline (MQ) a

88 henylamine, 2,4-dihydroxybenzophenone, and 2-hydroxy-4-methoxybenzophenone.

89 Herein, we synthesized (6-(3-hydroxy-4-methoxylphenyl)pyridin-2-yl) (3,4,5-trimethoxy

90 noic-2-O-beta-glucopyranoside (H3MP-G) and 2-hydroxy-4-methylpentanoic-2-O-beta-glucopyranoside acids

91 ction of diverse Gewald's aminothiophenes, 2-hydroxy-4-oxobut-2-enoic acid, and derivatives of cyanoa

92 zinium substrates at room temperature gave 3-hydroxy-4-pyridyl-isoquinoline derivatives in good yield

93 (4aR,5S,6R,8S,8aR)-5-(2-(Furan-3-yl)ethyl)-8-hydroxy-5,6,8a-trimethyl-3,4,4a,5,6,7,8,8a-octahydronaph

94 a novel transition-metal-free strategy to 5-hydroxy-5,6-dihydro-2(1H)pyridones is reported.

95 d levels of its mitogenic metabolite, 12-(S)-hydroxy-5,8,10,14-eicosatetraenoic acid (12-(S)-HETE) co

96 cific membrane antigen)-HBED-CC (N,N'-bis [2-hydroxy-5-(carboxyethyl)benzyl]ethylenediamine-N,N'-diac

97 ional artifactual increases in 2,6-diamino-4-hydroxy-5-formamidopyrimidine, 4,6-diamino-5-formamidopy

98 1 mixture of 2,5-dihydroxybenzoic acid and 2-hydroxy-5-methoxybenzoic acid (super-DHB) solubilized at

99 including 1,1-bis(3'-indolyl)-1-(3-chloro-4-hydroxy-5-methoxyphenyl)methane (Cl-OCH3) decreased expr

100 ion levels (e.g. 0.025 +/- 0.005 ng/mL for 4-hydroxy-5-methyl-3(2H)-furanone).

101 tic acid receptors (NMDAR) and alpha-amino-3-hydroxy-5-methyl-4-isox-azoleproprionic acid receptors (

102 systemic administration of an alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid receptor-pos

103 dendritic spine morphology and alpha-amino-3-hydroxy-5-methyl-4-isoxazole propionic acid/N-methyl-D-a

104 Kainate and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

105 ve the control of postsynaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

106 We tested whether alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

107 granule cell calcium-permeable alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

108 The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

109 of oligodendrocyte NMDARs and alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA) recept

110 red the dynamics of the TMD of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type i

111 glutamate ionotropic receptor alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid (AMPA)-type s

112 t not GluA1 subunit containing alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid and metabotro

113 t-like effects by potentiating alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMP

114 ves the regulation of synaptic alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMP

115 male mice, perhaps by altering alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor (AMP

116 romoting membrane insertion of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor AMPA

117 ation of the highly homologous alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptor by g

118 The alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AM

119 uR-mediated internalization of alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, a

120 Pase, GluA2 subunit containing alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors, an

121 Desensitization of the alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid subtype after

122 alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid(AMPA)-type gl

123 ific increase in GluA2-lacking alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid)-type glutama

124 cedented selectivity among ( S)-2-amino-3-(3-hydroxy-5-methyl-4-isoxazolyl)propionic acid (AMPA) rece

125 matergic neurotransmission via alpha-amino-3-hydroxy-5-methylisoxazole-4-propionic acid (AMPA)-type r

126 program led to the discovery of isosteric 7-hydroxy-5-oxopyrazolo[4,3-b]pyridine-6-carboxamide deriv

127 -N-cyclopropylmethyl-4,5-epoxy-6,14-ethano-3-hydroxy-6 methoxymorphinan-7-yl]-3,3-dimethylpentan-2-ol

128 t affect 2-AG or fluorogenic arachidonoyl, 7-hydroxy-6-methoxy-4-methylcoumarin ester (AHMMCE) substr

129 ults, we synthesized the novel ligand (E)-(7-hydroxy-6-methylhept-5-en-1-yl)phosphonate and mutated p

130 phocholine, O-1-O-palmitoyl-2-O-(5,8-dioxo-8-hydroxy-6-octenoyl)-l-glycero-3-phosphocholine, and othe

131 missed intermediate of the Dornow reaction-5-hydroxy-6-oxo-4-aryl-6H-1,2-oxazine-3-carboxylates.

132 -7,8-dihydro-alpha-ionol (Blumenol C), and 3-hydroxy-7,8-dihydro-beta-ionol, whereas a germination te

133 -long-chain moieties; phytosphingosine and 4-hydroxy-8-sphingenine were the predominant SB paired mai

134 sis, we previously proposed a structure of 8-hydroxy-9,11-dioxolane eicosatetraenoic acid (DXA(3)).

135 AM1710 (3-(1,1-dimethyl-heptyl)-1-hydroxy-9-methoxy-benzo(c) chromen-6-one), a cannabilact

136 of crotonic acid leads to 29 % yield of beta-hydroxy acid (3-hydroxybutanoic acid).

137 d acrylamide)s and oligo(2-substituted-alpha-hydroxy acid)s have been synthesized.

138 uced were converted into 2-oxolactones and 3-hydroxy acids and directly to ulosonic acid derivatives,

139 highlighted with almost 30 alcohols, diols, hydroxy acids, amines and amino alcohols, and the accura

140 f saturated fatty acids to high value chiral hydroxy-acids and lactones poses a number of synthetic c

141 lpha-, but not the gamma-isomers of ADABA or hydroxy-ADABA.

142 s by employing unprotected indoles and alpha-hydroxy aldehydes as coupling partners.

143 We conclude that hydroxy-alpha-ADABA might serve a similar function.

144 me for the photochemical transformation of 4-hydroxy-alpha-benzopyrones to a new series of biorelevan

145 atalyzes the glucosylation of allelopathic 3-hydroxy-alpha-damascone, 3-oxo-alpha-ionol, 3-oxo-7,8-di

146 ature under mild conditions by treating beta-hydroxy-alpha-diazo carbonyls with Sc(OTf)(3) .

147 l conformational perturbations induced by N-(hydroxy)amides are outweighed by a network of strong int

148 omally from dihydroxybenzoic acid and a beta-hydroxy amino acid that cyclizes into the beta-lactone d

149 didates bear multiple functionalities, e.g., hydroxy, amino, and carboxylic acid groups, glucuronidat

150 urcumin transformations and the formation of hydroxy and alkoxy adducts has not been reported yet.

151 However, the formation of hydroxy and alkoxy adducts of stevioside and of its hydr

152 Hydroxy and epoxy fatty acids from oleic and linoleic ac

153 GalE are suitable for accommodating both the hydroxy and N-acetyl groups of the substrate during suga

154 gation, where X can be amino, N-alkyl-amino, hydroxy, and thiol groups.

155 Amino-, hydroxy-, and thiol-groups in the meta positions of C-ph

156 Using N-hydroxy anilines as electrophiles, which can be easily a

157 Substituted hydroxy-benzofurans are easily accessible by treatment o

158 e, perfluorooctanoic acid (PFOA), atrazine-2-hydroxy, benzotriazole, acesulfame, and prometon were at

159 ine the effects of TRF, with or without beta-hydroxy beta-methylbutyrate (HMB) supplementation, durin

160 el nutritional supplement [comprised of beta-hydroxy beta-methylbutyrate (HMB), lutein, phospholipids

161 the C-O ether bonds in alpha-keto and alpha-hydroxy beta-O-4 type aryl ether linkages of lignin.

162 iketones, generating hydroxychlorin and beta-hydroxy-beta-ketodihydroporphyrin isomers, generally in

163 beta-Hydroxy-beta-methylbutyrate (HMB) is a nutrition supplem

164 olites including the leucine metabolite beta-hydroxy-beta-methylbutyrate, which was increased by AA s

165 was reported the synthesis of a novel poly(3-hydroxy butyrate)-b-poly(vinyl benzyl xanthate) block co

166 ts and revealed that highly bioavailable Pb (hydroxy)carbonate (indicative of Pb-based paint) was the

167 O layer followed by Mg(OH)(2), and magnesium hydroxy carbonates.

168 ure using the MCT-4 inhibitor, alpha-cyano-4-hydroxy-cinnamic acid (CHCA), a cinnamon derivative.

169 re generated by oxidation of corresponding N-hydroxy compounds with iodobenzene diacetate, [bis(trifl

170 48.84 ug/kg) > 15-Hydroxy-CUL (9.39 ug/kg) > Hydroxy -CUL (0.06 ug/kg) > 12-Hydroxy-CUL (0.05 ug/kg)

171 06 ug/kg) > 12-Hydroxy-CUL (0.05 ug/kg) > 14-Hydroxy-CUL (0.01 ug/kg).

172 9.39 ug/kg) > Hydroxy -CUL (0.06 ug/kg) > 12-Hydroxy-CUL (0.05 ug/kg) > 14-Hydroxy-CUL (0.01 ug/kg).

173 nce was CUL (70%) > 15-Hydroxy-CUL (47%) > 5-Hydroxy-CUL (15%) and their rank based on their concentr

174 tives based on occurrence was CUL (70%) > 15-Hydroxy-CUL (47%) > 5-Hydroxy-CUL (15%) and their rank b

175 y-CUL (99.21 ug/kg) > CUL (48.84 ug/kg) > 15-Hydroxy-CUL (9.39 ug/kg) > Hydroxy -CUL (0.06 ug/kg) > 1

176 heir rank based on their concentration was 5-Hydroxy-CUL (99.21 ug/kg) > CUL (48.84 ug/kg) > 15-Hydro

177 ce of culmorin (CUL) and its derivatives (15-Hydroxy-CUL and 5-Hydroxy-CUL.

178 L) and its derivatives (15-Hydroxy-CUL and 5-Hydroxy-CUL.

179 (CBD) and in one instance, the metabolite 11-hydroxy-Delta(9)-tetrahydrocannabinol (THC-OH).

180 of the DHA-derived monohydroxy fatty acid 17-hydroxy-DHA (HDHA) and unbalanced formation of SPMs (in

181 o-resolving lipid mediators (SPMs), e.g., 17-hydroxy-DHA and 18-hydroxy-EPA.

182 Seventy-three oxylipins, mostly hydroxy-, dihydroxy-, and epoxy-PUFAs, were quantified i

183 Here, we show 20-Hydroxy-Ecdysone (20HE)-signaling controlling organ home

184 roaches to unravel the core of ectoine and 5-hydroxy-ectoine catabolisms.

185 ains a new catalytic activity and forms 15 R hydroxy-eicosatetraenoic acid (15 R-HETE) as alternate p

186 e generated in situ from a readily available hydroxy-endoperoxide precursor.

187 ediators (SPMs), e.g., 17-hydroxy-DHA and 18-hydroxy-EPA.

188 of stereochemistry to form enantiopure beta-hydroxy esters.

189 lipopolysaccharide-copurified medium-chain 3-hydroxy fatty acid (mc-3-OH-FA) metabolites elicit LORE-

190 cts; and a reduced ratio of esterified omega-hydroxy fatty acid sphingosine ceramides (EOS-CERs) to n

191 Fatty acid esters of hydroxy fatty acids (FAHFAs) are a newly discovered clas

192 Fatty acid esters of hydroxy fatty acids (FAHFAs) are a recently discovered c

193 Production of hydroxy fatty acids (HFAs) in transgenic crops represent

194 s (CE), triacylglycerols, (O)-acylated omega-hydroxy fatty acids (OAHFA), cholesteryl sulfate, choles

195 amilies of previously unrecognized saturated hydroxy fatty acids (SHFAs), namely, hydroxystearic and

196 Among cutin compounds, omega-hydroxy fatty acids and polyhydroxy-fatty acids were spe

197 gosines (Cer[NS]) and ceramides containing a-hydroxy fatty acids and sphingosines (Cer[AS]) decreased

198 ipase A IIIbeta facilitates the exclusion of hydroxy fatty acids from phosphatidylcholine in developi

199 the fortification of avocado puree with some hydroxy fatty acids, which deserved marked attention due

200 d fatty acids (NVOFAs), especially epoxy and hydroxy fatty acids, which potentially provide off-flavo

201 rs, and cholesteryl esters of (O)-acylated w-hydroxy fatty acids.

202 studied the production and incorporation of hydroxy-fatty acids (HFA) onto TAG in Arabidopsis (Arabi

203 sis of 14,15-dimethyl-FDP, 12-methyl-FDP, 12-hydroxy-FDP, homo-FDP, and 15-methyl-FDP was also achiev

204 ds, primarily betulinic acid, friedelin, and hydroxy-friedelin.

205 re available for the catalytic activation of hydroxy functional groups as a way to promote their dire

206 A single-step synthesis of 4-hydroxy-functionalized bi-aryl and aryl/alkyl ketones vi

207 e double-faced nature of hydrogen bonding in hydroxy-functionalized ionic liquids by means of neutron

208 thesized 9H-fluorene derivatives afforded 9H-hydroxy-functionalized quaternary fluorene derivatives i

209 ization to install the alpha-alkylidene-beta-hydroxy-gamma-butyrolactone.

210 cient optically active synthesis of the beta-hydroxy-gamma-lactone derivative with high enantiomeric

211 nol (-)-myrocin G (4) to the corresponding 5-hydroxy-gamma-lactone isomer myrocin C (1) are also deta

212 These features include hydroxy-glutamine in the peptide core instead of a serin

213 arkably short beta-sheet by incorporating N-(hydroxy)glycine (Hyg) residues into the backbone of pept

214 2H) plays a major role in the formation of 2-hydroxy glycosphingolipids, main components of myelin.

215 dictate the spectral response of individual hydroxy group (OH) oscillators.

216 atalyst, the nucleophilicity of the phenolic hydroxy group in salicylaldehyde reduces further to make

217 e analogs but failed in delivering a crucial hydroxy group in the final step.

218 substituents in both positions ortho to the hydroxy group inhibited BDA and Cl-BDA formation, but th

219 stalled a photolabile structural cage on the hydroxy group of D-F07 to generate PC-D-F07.

220 Upon photoactivation, the re-exposed hydroxy group on D-F07 triggered the aldehyde-protecting

221 the steric hindrance in the vicinity of the hydroxy group.

222 dendritic rods constructed by placing a tri(hydroxy) group at the apex of dendritic oligo-fluorenes

223 Interactions between methoxy and hydroxy groups are found to reduce membrane partitioning

224 acids to form reversible covalent bonds with hydroxy groups can be exploited to enable both electroph

225 ed for wasteful stoichiometric activation of hydroxy groups into halides or sulfonates.

226 hin a MOF that features open metal sites and hydroxy groups on the pore walls can serve as a highly e

227 ation of graphite, to produce both epoxy and hydroxy groups on the surface of fullerenes (C(60)) and

228 hatic polyols do not require a threo pair of hydroxy groups to form hypercoordinated Si complexes, al

229 nds displaying amino groups, carboxy groups, hydroxy groups, or triazolo-pyridines, which should enab

230 at undergo transesterification with residual hydroxy groups.

231 on between aryl fluorosulfates and silylated hydroxy groups.

232 the authors present a new material poly[3-(6-hydroxy)hexylthiophene] (P3HHT) that is able to transpor

233 ively correlated with 3-hydroxybutyric-acid, hydroxy-hydrocinnamic acid, and betaine whereas Bifidoba

234 isoprene SOA components, including isoprene hydroxy hydroperoxide (ISOPOOH), isoprene-derived epoxyd

235 Hydroxy, hydroperoxy, and keto products of 2-arachidonoy

236 evolution of inducible defense metabolite 4-hydroxy-ICN in Arabidopsis thaliana.

237 g aluminium oxide by specific retention of 5-hydroxy isoflavone.

238 esponsible for specifically glycosylating 12-hydroxy-jasmonic acid (12-OH-JA) and thereby producing 1

239 The identification of two new hydroxy ketones, 2-hydroxy-3-methylnonan-4-one (syn- and

240 ycloannulation process of indanone-derived 2-hydroxy ketoxime ethers with 1,4-bisnucleophilic indol-2

241 tophan to the active kynurenine metabolite 3-hydroxy-kynurenine between patients with MGUS and MM.

242 Here, we elucidate the biogenesis of the 4-hydroxy-l-citrulline unit and establish the role of an i

243 With the exception of the 3-hydroxy-l-pipecolic acid unit, little is known about the

244 Recently, a GRE, trans-4-hydroxy-L-proline (Hyp) dehydratase (HypD), was discover

245 The crosslinks hydroxy-lysino-norleucine (HLNL), dihydroxy-lysino-norle

246 acile pathway for the synthesis of alpha-((4-hydroxy/methoxyphenyl)selanyl)-aryl alkyl/alkyl ketones

247 toxic siderophore-inspired chelator, 2,6-bis[hydroxy(methyl)amino]-4-morpholino-1,3,5-triazine (H(2)B

248 istinguished between forage types were Lund, hydroxy-methyl-furfural and ash content.

249 gnificant accumulation of nicotinamide and 4-hydroxy-methylglycine in PGPR and PGR treated plants at

250 ing is linked to two polymorphisms in serine hydroxy-methyltransferase 8 (SHMT8).

251 40 known mogroside compounds, only 11-alpha-hydroxy-mogrosides exhibit a sweetening effect, whereas

252 etermine selectively the content of 11-alpha-hydroxy-mogrosides in these dried fruits and thus to pre

253 [3,4-b]pyrazin-5-ol core, which utilizes the hydroxy moiety as the proton transporter across the mito

254 nts further indicated that the substrate's 4-hydroxy moiety is required for catalysis and that this m

255 ay upon exposure to either l-NMA or N(delta)-hydroxy-N(omega)-methyl-l-Arg (l-HMA).

256 ges the triply modified arginine to N(delta)-hydroxy-N(omega)-methyl-N(omega)-nitroso-l-citrulline, t

257 The formation of a suite of isoprene-derived hydroxy nitrate (IHN) isomers during the OH-initiated ox

258 tion of BCP-peroxy with NO produces bicyclic hydroxy nitrate with a branching ratio <0.2%, indicating

259 n this study, the preparation of chiral beta-hydroxy nitriles catalyzed by alcohol dehydrogenase (Adh

260 s the potential to produce a variety of beta-hydroxy nitriles with different structures.

261 tem to prepare the corresponding chiral beta-hydroxy nitriles.

262 s, 2-amino-6-boronohexanoic acid (ABH) and N-hydroxy-nor-l-arginine (nor-NOHA).

263 xperiments have recently demonstrated that 2-hydroxy-NQs (2-OH-NQs) act as highly specific noncovalen

264 of the anti-HIV drug nevirapine (NVP) to 12-hydroxy-NVP (12-OHNVP) has been implicated in NVP toxici

265 was transformed by nearly all strains into 6-hydroxy-O-desmethylangolensin (6-hydroxy-O-DMA), but no

266 ains into 6-hydroxy-O-desmethylangolensin (6-hydroxy-O-DMA), but no dihydrogenistein production was r

267 d, suggesting the degradation of O-DMA and 6-hydroxy-O-DMA.

268 leading to high levels of mono, di-, and tri-hydroxy-octadecenoic acids.

269 Z-trifluoromethyl-substituted alkenes with a hydroxy or carboxylic acid group were thus prepared in 5

270 tive Mo- or Ru-based complex, treatment of a hydroxy- or a carboxylic-acid-containing olefin with com

271 sensing rate enhancements were found for a 2-hydroxy palladacycle derivative, which was used in subse

272 They were found, along with hydroxy-PCBs, in soil samples coming from a site histori

273 ce the levels of hydroxy-sulfonated-PCBs and hydroxy-PCBs.

274 Starting from 3-hydroxy piperidines, a novel transition-metal-free strat

275 measured in all participants include urinary hydroxy-polycyclic aromatic hydrocarbons, volatile organ

276 rmation of the disaccharide moiety at the 4'-hydroxy position of the MbA flavonol core.

277 4), as well as Raman bands at 856 cm(-1) for hydroxy-proline (R = -0.68, p = 0.0056) and at 1032 cm(-

278 milarly, 5, 12-, and 15-lipoxygenase-derived hydroxy-PUFAs as well as those formed autoxidatively inc

279 = -0.68, p = 0.0056) and at 1032 cm(-1) for hydroxy-pyridinium (R = 0.74, p = 0.0016).

280 We used hydroxy-radical foot printing with mass spectroscopy (XF

281 om Shaker potassium channel in 1-palmitoyl-2-hydroxy-sn-glycero-3-phospho-(1'-rac-glycerol) (LPPG) mi

282 sed macrolides similar to peloruside A and a hydroxy sphingosine derivative are suggested to be signi

283 Palmitic acid esters of hydroxy stearic acids (PAHSAs) are bioactive lipids with

284 Palmitic acid esters of hydroxy stearic acids (PAHSAs) are endogenous antidiabet

285 reoselective hydride reductions provided the hydroxy substituent at C2', which then controls the ster

286 evels in soils and about twice the levels of hydroxy-sulfonated-PCBs and hydroxy-PCBs.

287 redox-reporter-modified protein variant to a hydroxy-terminated monolayer on a gold surface and then

288 THC and its main first-pass metabolites (11-hydroxy-THC and 11-nor-9-carboxy-THC) in blood and brain

289 fic elevation in the bioactive metabolite 11-hydroxy-THC.

290 -tri-tert-butylphenol Ar(3)OH, and butylated hydroxy-toluene Ar(4)OH, are effective electrochemical m

291 hydroperoxides, malondialdehyde (MDA) and 4-hydroxy-trans2-hexenal (HHE) in both herring and salmon

292 Furthermore, bis-5-hydroxy-tryptamide-diethylenetriaminepentaacetate gadoli

293 (CM) mouse model with a combination of bis-5-hydroxy-tryptamide-diethylenetriaminepentaacetate gadoli

294 uveitis showed significantly lower serum 25-hydroxy vitamin D levels than inactive uveitis patients

295 Serum 25-hydroxy vitamin D levels were compared between active an

296 Serum 25-hydroxy vitamin D levels were compared between patients

297 s and population-based estimates of serum 25-hydroxy vitamin D levels, stratified by geographic regio

298 ll participants (n = 151) underwent serum 25-hydroxy vitamin D measurement and completed a questionna

299 receptor, retinol-binding protein (RBP), 25-hydroxy vitamin D, folate, and vitamin B12; and a panel

300 sation of geranylgeranyl diphosphate into 11-hydroxy vulgarisane, the likely biosynthetic precursor o