ライフサイエンスコーパス: hydroxyprogesterone

1 2)H]-progesterone; and 21,21,21-[(2)H(3)]-17-hydroxyprogesterone.

2 ydroxylase and no lyase activity for 17alpha-hydroxyprogesterone.

3 18, which converts progesterone into 20alpha-hydroxyprogesterone.

4 th progesterone as substrate and not 17alpha-hydroxyprogesterone.

5 ted serum levels of its enzymatic product 17-hydroxyprogesterone (17-OHP).

6 terone to 11-deoxycorticosterone and 17alpha-hydroxyprogesterone (17alpha-OH-progesterone) to 11-deox

7 al structure complexed with the substrate 17-hydroxyprogesterone (17OHP) was determined to 3.0 A reso

8 hyperplasia variants associated with 17alpha-hydroxyprogesterone accumulation.

9 iated with SIDS in a univariate analysis: 17-hydroxyprogesterone, alanine, methionine, proline, tyros

10 We reinvestigated the 17alpha-hydroxyprogesterone and 17alpha-hydroxypregnenolone 17al

11 nediol, 17alpha-hydroxypregnanolone, 17alpha-hydroxyprogesterone, and 21alpha-hydroxyprogesterone) we

12 hormone into its inactive metabolite 20alpha-hydroxyprogesterone, and toxicologically this enzyme act

13 ely, restored the rate of formation of 6beta-hydroxyprogesterone by the hybrid to that of 3A12.

14 trial that identified a benefit of 17-alpha-hydroxyprogesterone caproate (17OHP-C) in reducing the r

15 17 alpha-hydroxyprogesterone caproate (17P) has been shown in som

16 In singleton gestations, 17 alpha-hydroxyprogesterone caproate (17P) has been shown to red

17 al small trials have suggested that 17 alpha-hydroxyprogesterone caproate (17P) may reduce the risk o

18 We observed that neither systemic 17a-hydroxyprogesterone caproate (Makena) nor vaginal proges

19 to prevent premature labor, such as 17-alpha-hydroxyprogesterone caproate and dydrogesterone, reveali

20 Treatment with 17 alpha-hydroxyprogesterone caproate did not reduce the rate of

21 is cross-sectional study examines changes in hydroxyprogesterone caproate fills from 2010 through 202

22 etabolize ammonia, testosterone, and 17alpha-hydroxyprogesterone caproate, and expressed inducible fe

23 17OHPC (17alpha-hydroxyprogesterone caproate; 0.68, 0.43 to 1.02, modera

24 with a reduction in the basal serum 17 alpha-hydroxyprogesterone concentration from 135 +/- 21 to 66

25 he leuprolide-stimulated peak serum 17 alpha-hydroxyprogesterone concentration from 455 +/- 54 to 281

26 Screening of neonates with elevated 17-hydroxyprogesterone concentrations for classic (severe)

27 o seen in treated children (reductions of 17-hydroxyprogesterone, corticosterone, 11-deoxycortisol an

28 rotein 15 and follistatin) and promoting (17-hydroxyprogesterone) factors for oocyte maturation were

29 ining two molecules of the substrate 17alpha-hydroxyprogesterone, has been used as a template for und

30 rated conversion of progesterone to 17 alpha-hydroxyprogesterone in response to stimulation by gonado

31 We then demonstrate that 20alpha-hydroxyprogesterone is more abundant in oldfield mice, w

32 Although 17alpha-hydroxyprogesterone is only observed farther from the ca

33 measurement of dehydroepiandrosterone and 16-hydroxyprogesterone may allow better diagnostic accuracy

34 A similar stimulation of 17alpha-hydroxyprogesterone metabolism is seen when studying the

35 nor conformation may yield the minor 16alpha-hydroxyprogesterone metabolite.

36 vels of maternal estradiol, testosterone, 17-hydroxyprogesterone (OHP), and cortisol from the first t

37 ehydroepiandrosterone was associated with 16-hydroxyprogesterone (p < 0.001), which was also signific

38 rogesterone to 17-hydroxypregnenolone and 17-hydroxyprogesterone, respectively (17alpha-hydroxylase a

39 e androgen biosynthesis pathway from 17alpha-hydroxyprogesterone to 5alpha-dihydrotestosterone, which

40 ciency (kcat/Km) for the cleavage of 17alpha-hydroxyprogesterone to androstenedione compared with wil

41 ntrations and the response of serum 17 alpha-hydroxyprogesterone to leuprolide, a gonadotrophin-relea

42 The serum 17 alpha-hydroxyprogesterone values increased slightly in the pla

43 dependent on whether the ligand was 17alpha-hydroxyprogesterone versus ketoconazole.

44 that androstenedione formation from 17alpha-hydroxyprogesterone via the minor delta4-steroid pathway

45 ne, 17alpha-hydroxyprogesterone, and 21alpha-hydroxyprogesterone) were detected and removed effective

46 alpha-hydroxypregn-4-ene-3,20-dione (11alpha-hydroxyprogesterone) were used as starting materials for

47 acenta by converting progesterone to 20alpha-hydroxyprogesterone, where progesterone is essential for

48 glucuronide, testosterone-glucuronide and 17-hydroxyprogesterone), which belonged to the steroid bios

49 d-type CYP21A2 also forms a trace of 16alpha-hydroxyprogesterone, which increased with 21,21,21-[(2)H

50 0 alpha-dihydroprogesterone and [3H]17 alpha-hydroxyprogesterone, which reached 61% (median, 14%) and