ライフサイエンスコーパス: hydroxyquinoline

1 timicrobial tolerance to chloroxylenol and 8-hydroxyquinoline.

2 y a colloidal solution of Fe-nanoparticles/8-hydroxyquinoline.

3 on-transfer behavior than that of its parent hydroxyquinoline.

4 ynthetic complex formed between Cu(2+) and 8-hydroxyquinoline.

5 lex proton-transfer behavior than its parent hydroxyquinoline.

6 ransfer between the gold nanoparticles and 8-hydroxyquinoline.

7 of corrosion of pure aluminum by CeCl3 and 8-hydroxyquinoline.

8 vailable quinolinols, as well as synthesized hydroxyquinolines.

9 works on both 2- and 4-hydroxypyridines and -hydroxyquinolines.

10 Isomeric 5-, 6-, 7-hydroxyquinolines (11-13) and 5-hydroxyisoquinoline (14)

11 d 11.1-14.8 MBq (300-400 micro Ci) (111)In-8-hydroxyquinoline ((111)In-oxine) or (111)In-mercaptopyri

12 ethers 17-19 by reductive amination using 8-hydroxyquinoline-2-carboxaldehyde.

13 N-Formylkynurenine (NFK) at pH 7.0 and 4-hydroxyquinoline (4-OH Q) and kynurenic acid (Kyn-A) at

14 Compounds 11, 13, 14, and 8-hydroxyquinoline (5) underwent selective ionic hydrogena

15 ing aluminum ions with the chelating agent 8-hydroxyquinoline-5-sulfonic acid (HQS) to form Al(HQS)3,

16 he Zn2+ chelators 1,10-O-phenanthroline or 8-hydroxyquinoline-5-sulfonic acid results in dissociation

17 The electrochemiluminescence (ECL) of tris(8-hydroxyquinoline-5-sulfonic acid)aluminum(III) in aqueou

18 zinc when treated with the metal chelator 8-hydroxyquinoline-5-sulfonic acid.

19 ansport pathways of bifunctional photoacid 7-hydroxyquinoline (7HQ) in water/methanol mixtures.

20 s utilized in the arrays comprise the same 8-hydroxyquinoline (8-HQ) receptor and various conjugated

21 The 8-hydroxyquinolines (8-HQ) clioquinol (CQ) and PBT2 were d

22 One group of hit compounds was 8-hydroxyquinolines (8-OHQ), a class of clinically relevan

23 Of approximately 30 hits, several were 8-hydroxyquinolines (8-OHQs).

24 helation-enhanced fluorescence property of 8-hydroxyquinoline (8HQ) following Ca(2+) complexation wit

25 ommercially available or newly synthetized 8-hydroxyquinoline (8OHQ) derivatives whose toxicity is pa

26 arbomethoxy-2,2'-bipyridine 8 or 5-carboxy-8-hydroxyquinoline 9, two 2-oxoglutarate competitive templ

27 The sensor functionalized with 8-hydroxyquinoline allowed sensing through inducing Donnan

28 on the common organic semiconductor tris-(8-hydroxyquinoline)aluminium in the range +/-500 uT displa

29 agnetoelectroluminescence (MEL) of a tris-(8-hydroxyquinoline)aluminium-based (Alq(3)) OLED within th

30 nterrogate interfaces formed between tris-(8-hydroxyquinoline) aluminum (Alq(3)) and vapor-deposited

31 00% at T = 10 K) has been reached in tris-(8-hydroxyquinoline) aluminum (Alq(3))-based organic spin v

32 l organic electroluminescent molecule tris(8-hydroxyquinoline) aluminum (Alq(3)).

33 of a thin-film organic semiconductor tris-(8-hydroxyquinoline) aluminum (Alq3) doped with DCM laser d

34 Working examples of tris(8-hydroxyquinoline)aluminum(III)-based OLEDs have been fab

35 rs) of organic semiconductors, Alq3 (Tris-(8-hydroxyquinoline)aluminum) and DSA-Ph (1,4-di-[4-(N,N-di

36 e from an Alq(3)/TPD heterojunction (tris-(8-hydroxyquinoline)aluminum/N,N'-bis(3-methylphenyl)-N,N'-

37 methods for monitoring levels of 2-heptyl-4-hydroxyquinoline and 2,4-dihydroxyquinoline, as well as

38 ct of the metal on fluorescent emission of 8-hydroxyquinoline and o-phenanthroline at lambda(em) = 36

39 The difference between the lowest energy hydroxyquinoline and quinolone forms is 27 and 38 kJ mol

40 eactions to generate in situ O,4-didehydro-2-hydroxyquinolines and O,4-didehydro-2-hydroxypyridines,

41 ry and abortive ternary complex containing 8-hydroxyquinoline, and contrast with previously reported

42 cules-ciclopirox olamine (CPX), piroctone, 8-hydroxyquinoline, and deferasirox-were also shown to eff

43 and we extended this effect to piroctone, 8-hydroxyquinoline, and deferasirox.

44 4-(2-hydroxyethyl) piperazin-1-yl (methyl)-8-hydroxyquinoline], and its derivative M30 [5-(N-methyl-N

45 nickel, lead and zinc at trace level using 8-hydroxyquinoline as a chelating agent and lanthanum(III)

46 Using 8-hydroxyquinoline as a colloidal agent, a new, fast, and

47 ion of copper from biological samples with 8-hydroxyquinoline as a colorimetric indicator affords a m

48 n was made feasible by the use of 5-chloro-8-hydroxyquinoline as a ligand along with NiBr(2) .DME as

49 izes tetraethylammonium carbonate as base, 8-hydroxyquinoline as ligand, and H2O as cosolvent.

50 is the first study providing evidence for 8-hydroxyquinolines as novel inhibitors of the IN-LEDGF/p7

51 sh this, fullerene was functionalized with 8-hydroxyquinoline at different ligand positions and their

52 equilibrium of the immobilized ligand, p-((8-hydroxyquinoline)azo)benzenethiol (SHQ).

53 scribe the synthesis of novel, red-shifted 8-hydroxyquinoline-based fluorophores and their incorporat

54 a fluorescent and uncharged double-stranded hydroxyquinoline-based zinc(II) helicate with the abilit

55 8-Bromo-7-hydroxyquinoline (BHQ) is efficiently photolyzed by clas

56 l synthesis is used to develop multiligand 8-hydroxyquinoline binding sites in porous silica structur

57 air of Q-PNA strands that each contain one 8-hydroxyquinoline, but below the melting temperature, the

58 c octadepsipeptides possessing two pendant 3-hydroxyquinoline chromophores, are described in which th

59 use hearts and were superfused with Fe(3+)/8-hydroxyquinoline complex (5-100 uM).

60 myocytes superfused with 15 umol/L Fe(3+)/8-hydroxyquinoline complex.

61 ry to previous reports, clioquinol and other hydroxyquinoline compounds do not act as direct proteaso

62 ifications at the C5 and C7 carbons of the 8-hydroxyquinoline core improved potency, but reduction of

63 his context, revisiting known classes like 8-hydroxyquinolines could be an interesting strategy to di

64 investigated molecular targets concerning 8-hydroxyquinoline derivatives are explored in the final s

65 The 8-hydroxyquinoline derivatives nitroxoline and clioquinol

66 hemical space around previously identified 8-hydroxyquinoline-derived Mannich bases with robust MDR-s

67 hanum(III) as a carrier element, amount of 8-hydroxyquinoline, duration of co-precipitation was exami

68 Here, we report the discovery of a hydroxyquinoline family of small molecules that can acti

69 very of iron with membrane-permeant Fe(3+)/8-hydroxyquinoline (FeHQ) quenched MFF fluorescence by ~80

70 QE and 7Me-OQE show clear preference for the hydroxyquinoline form.

71 interface , we developed a set of modified 8-hydroxyquinoline fragments demonstrating micromolar IC50

72 such as Cu2+, Co2+, Ni2+, and Zn2+ bind to 8-hydroxyquinoline groups covalently attached to the PCCAC

73 describe the discovery of a series of novel hydroxyquinoline GRP78 inhibitors.

74 nt and general method for the synthesis of 3-hydroxyquinolines has been achieved from o-acylanilines

75 2-Heptyl-4-hydroxyquinoline (HHQ) and Pseudomonas quinolone signal

76 s using the cocrystal structure of 5-nitro-8-hydroxyquinoline in the cathepsin B active site.

77 ve M30 [5-(N-methyl-N-propargyaminomethyl)-8-hydroxyquinoline] in vivo to test their neuroprotective

78 stent indications that cerium chloride and 8-hydroxyquinoline inhibit corrosion effectively.

79 onitored with the fiber, it was shown that 8-hydroxyquinoline is a more effective inhibitor than ceri

80 tended conjugated chromophores attached to 8-hydroxyquinoline is reported.

81 -yielding iodination of hydroxypyridines and hydroxyquinolines is described.

82 N-Oxidation of hydroxyquinolines leads to a dramatic increase in their

83 Strategic substitution of 8-hydroxyquinoline ligands and control of the structural s

84 ruthenium coordination complexes containing hydroxyquinoline ligands were synthesized that exhibited

85 The present study uses iron (Fe/hydroxyquinoline)-mediated injury of cultured human prox

86 the structure of one such factor, 2-methyl-4-hydroxyquinoline (MHQ).

87 olid-phase extraction of the analyte on an 8-hydroxyquinoline microcolumn.

88 udying the 10-hydroxybenzo[h]quinoline and 8-hydroxyquinoline molecules using anion photoelectron spe

89 i-walled carbon nanotubes coated with poly 8-hydroxyquinoline (MWCNTs/Fe(3)O(4)@PHQ) as a novel sorbe

90 ndependent tobramycin uptake, and 2-heptyl-4-hydroxyquinoline N-oxide (HQNO) induces multidrug tolera

91 lerae by the specific inhibitor 2-n-heptyl-4-hydroxyquinoline N-oxide (HQNO) resulted in elevated tox

92 and menD) or chemically, using 2-n-heptyl-4-hydroxyquinoline N-oxide (HQNO), inhibited both growth a

93 one, gramicidin, Triton X-100, or 2-heptyl-4-hydroxyquinoline N-oxide (HQNO).

94 to the P. aeruginosa exoproduct, 2-heptyl-4-hydroxyquinoline N-oxide (HQNO).

95 are sensitive to the inhibitor 2-n-heptyl-4-hydroxyquinoline N-oxide (HQNO).

96 The addition of 2-(n-heptyl)-4-hydroxyquinoline N-oxide to whole cells or purified memb

97 ubiquinone or its analog HQNO (2-n-heptyl-4-hydroxyquinoline N-oxide) from Na(+)-NQR, which indicate

98 f Na(+)-NQR inhibitor (DBMIB or 2-n-heptyl-4-hydroxyquinoline N-oxide) indicate that two quinone anal

99 tridecyl-stigmatellin) and 3.25-A (2-nonyl-4-hydroxyquinoline N-oxide) resolution.

100 quinone analogues menadione and 2-n-heptyl-4-hydroxyquinoline N-oxide, identifying a hydrophobic plat

101 tween ubiquinone-1 and DBMIB or 2-n-heptyl-4-hydroxyquinoline N-oxide, respectively.

102 a production of the antimicrobial 2-heptyl-4-hydroxyquinoline N-oxide, while the antimicrobial pyocya

103 sic and more acidic than the parent and adds hydroxyquinoline N-oxides to the class of high-acidity e

104 We demonstrate here that 2-n-heptyl-4-hydroxyquinoline-N-oxide (HQNO), a Pseudomonas aeruginos

105 branes were highly sensitive to 2-n-heptyl-4-hydroxyquinoline-N-oxide (IC(5)(0) = approximately 1 mum

106 wn quinol-binding site inhibitors 2-heptyl-4-hydroxyquinoline-N-oxide and 2-[1-(p-chlorophenyl)ethyl]

107 steady-state emission characterization of 6-hydroxyquinoline-N-oxide and 2-methyl-6-hydroxyquinoline

108 n combination with antimycin or 2-n-heptyl-4-hydroxyquinoline-N-oxide in combination with myxothiazol

109 The quinone analogue 2-heptyl-4-hydroxyquinoline-N-oxide inhibited C. thermarum NDH-2 ac

110 of 6-hydroxyquinoline-N-oxide and 2-methyl-6-hydroxyquinoline-N-oxide reveals a rich but less complex

111 er antimycin or myxothiazol (or 2-n-heptyl-4-hydroxyquinoline-N-oxide, (E)-methyl-3-methoxy-2-(4'-tra

112 ecific inhibitors myxothiazol and 2-heptyl-4-hydroxyquinoline-N-oxide.

113 d form bound to a menadiol analog 2-heptyl-4-hydroxyquinoline-N-oxide.

114 the effect of the Q(i) site inhibitor 2-N-4-hydroxyquinoline-N-oxide.

115 this class in the perspective of using the 8-hydroxyquinoline nucleus for the search for novel antimi

116 al targets and the privileged structure of 8-hydroxyquinoline nucleus have prompted an increased inte

117 We have introduced 8-hydroxyquinoline Q in 10-mer PNA strands with various se

118 Herein, we investigated 8-hydroxyquinoline (quinolin-8-ol) as a potential inhibito

119 ene film containing gold nanoparticles and 8-hydroxyquinoline sandwiched between two metal electrodes

120 atrithia-16-crown-5 ligands containing two 8-hydroxyquinoline sidearms are reported.

121 Thus, the possibility of 4-oxoquinoline/4-hydroxyquinoline tautomerism may impact in pharmacologic

122 ations form bisliganded complexes with two 8-hydroxyquinolines that cross-link the hydrogel and cause

123 In the case of 2-substituted quinolines, 3-hydroxyquinoline was observed as the main product via a

124 1% m/v 8-Hydroxyquinoline was used as the modifier to enhance the

125 A specific PON1 inhibitor, 2-hydroxyquinoline, was used to confirm that the observed

126 rable binding of the "privileged" fragment 8-hydroxyquinoline with HIV-1 integrase (IN) at the IN-len

127 acuum-deposited thin films of zinc(II) bis(8-hydroxyquinoline) (Znq(2)).