ライフサイエンスコーパス: hyperactivated

1 duced while ER O-glycosylation initiation is hyperactivated.

2 without AKI; however, fibrinolysis remained hyperactivated.

3 id cells in disease states where p21(ras) is hyperactivated.

4 lls in which the beta-catenin/Tcf pathway is hyperactivated.

5 ast some CSF-1R-associated proteins also are hyperactivated.

6 immune responses and blocks development when hyperactivated.

7 arental Kras(G12D) mice, where STAT3 was not hyperactivated.

8 ome various barriers, their motility must be hyperactivated, a motion that is characterized by vigoro

9 -derived mast cells from CblbH257L mice were hyperactivated after FcepsilonRI cross-linking, and Cblb

10 nhibition of the Rheb-mTOR pathway, which is hyperactivated after loss of TSC2, decreased MCP-1 produ

11 However, if mTORC1 was hyperactivated after myelination onset, radial hypermyel

12 Because LNCaP cells have hyperactivated Akt function due to PTEN inactivation, we

13 ncer agent for patients whose tumors express hyperactivated Akt.

14 Hyperactivated AKT/mTOR signaling is a hallmark of pancr

15 Strains harboring a hyperactivated allele of CDC28 that is CAK1 independent

16 Lyn-deficient DCs were hyperactivated and hyperresponsive to Toll-like receptor

17 d progenitor cells (HSPCs), whereas they are hyperactivated and lost in the circulation when wild-typ

18 Lat2(-/-) T cells were hyperactivated and produced more cytokines than Lat2(+/+

19 urther that CD4+ T cells of 4.1R-/- mice are hyperactivated and that they displayed hyperproliferatio

20 hock sensitivity of a strain in which RAS is hyperactivated and the heat shock sensitivity of a wscDe

21 /RSK MAPK signaling module is constitutively hyperactivated, and Bad is maintained in its inactive st

22 Lymphocytes from these transgenic mice were hyperactivated, and T cells produced large amounts of ty

23 Aurora kinases A, B, and C, were found to be hyperactivated, and the altered expression of CDK1 was f

24 Thus, neither costimulatory tumor cells nor hyperactivated antitumor lymphocytes were sufficient to

25 Nevertheless, doubly deficient B cells were hyperactivated, as evidenced by extremely elevated serum

26 is self-defense mechanism to save cells from hyperactivated autophagy upon prolonged oxidative stress

27 rine lupus, we show that murine IRF5 becomes hyperactivated before clinical onset.

28 Hyperactivated beta-catenin is a commonly found molecula

29 ession and binding to p300 may contribute to hyperactivated beta-catenin transcriptional activity in

30 Mechanisms to mute hyperactivated brain regions and delink dysregulated neu

31 increased parasympathetic signaling leads to hyperactivated bronchoconstriction and abnormal respirat

32 e, extramedullary splenic erythropoiesis was hyperactivated, but this did not lead to accelerated rec

33 nnel critical for mechanosensation that when hyperactivated by a mec-4(d) mutation induces necrosis o

34 ntal analyses have demonstrated that IRF5 is hyperactivated by a pathogenic allele of TNPO3 through l

35 s, most genes from the male X chromosome are hyperactivated by a special dosage compensation system.

36 d T257I are inhibited, the other mutants are hyperactivated by AdoMet.

37 way was particularly emphasized when ECS was hyperactivated by AEA and in ob/ob tissue.

38 Mus81-Mms4 is hyperactivated by Cdc5-mediated phosphorylation in meios

39 dentate gyrus granule cells (dGCs) that are hyperactivated by chemoconvulsant administration or sens

40 bnormal automaticity when these channels are hyperactivated by elevated Ca(2+) .

41 Consequently, HSCs are hyperactivated by interleukin-1beta and possibly other p

42 genes), in which the reporter construct was hyperactivated by low temperature, but not by abscisic a

43 ns between MPFC and DLPFC, a region that was hyperactivated by patients and relatives during WM perfo

44 Caenorhabditis elegans DEG/ENaC MEC-4 is hyperactivated by the (d) mutation and induces death of

45 al RNA methylation, was identified as a gene hyperactivated by the BL-associated Myc mutants.

46 In each case, the target is hyperactivated by the drug.

47 Here, we found that hyperactivated c-Met led to increased NF-kappaB signalin

48 vation of c-Raf containing mutated W342 in a hyperactivated c-Raf, but not in a wild type c-Raf and (

49 nases (TALERs): engineered fusions between a hyperactivated catalytic domain from the DNA invertase G

50 oly(ADP-ribose) polymerase-1 (PARP-1) can be hyperactivated, causing (ADP-ribosyl)ation of nuclear pr

51 cumulation of proinflammatory CD57(+)CD28(-) hyperactivated CD8(+) T cells that may promote atheroscl

52 ction after reduction of IL-2 consumption by hyperactivated CD8(+) T cells.

53 ojection extension is stimulated by Bem1 and hyperactivated Cdc42.

54 partial inhibition of the spliceosome in MYC-hyperactivated cells leads to global intron retention, w

55 tor 2 (TRAF2), are upstream of JNK in PARP-1 hyperactivated cells, because PARP-1-induced JNK activat

56 protein (MAP) kinase (MAPK) is significantly hyperactivated compared with ERalpha+ breast cancer.

57 es in sarcomas where PI3K and mTOR are often hyperactivated could improve the suitable recruitment of

58 h increasing prevalence, is characterized by hyperactivated cytokines of helper T cell subset 2 and i

59 1) and Hop(T42) both hyperphosphorylated and hyperactivated D-Stat when overexpressed in Drosophila c

60 Furthermore, A20-silenced, hyperactivated DCs exhibited an enhanced homing capacity

61 Because hyperactivated DDC signalling can lead to a persistent a

62 Hyperactivated DEG/ENaCs induce neuronal death through e

63 al that an important mTOR substrate is found hyperactivated downstream of Myc oncogenic activity to p

64 TMEM16F-deficient T cells are hyperactivated during the early phase of infection, exhi

65 cell death, all phenotypes characteristic of hyperactivated EGFR signaling.

66 pressed in body wall muscle precursor cells, hyperactivated EGL-15 can also interfere with the proper

67 size in roots, premature cell expansion and hyperactivated endocycle in leaves.

68 ulin-binding region from ACVIII results in a hyperactivated enzyme state and a loss of Ca2+ sensitivi

69 In cystic fibrosis airway epithelia, a hyperactivated epithelial Na(+) conductance operates in

70 This hyperactivated ERK, calcium signaling, and ER stress, au

71 gh incidence of activating RAS mutations and hyperactivated ERK1/2 signaling observed in many human t

72 Hyperactivated extracellular signal-regulated kinase (ER

73 ld-type ezrin, closed ezrin, open ezrin, and hyperactivated ezrin.

74 broken allele also suppresses the effects of hyperactivated FGF but not EGF receptors.

75 FGF and can be phosphorylated in response to hyperactivated FGF signaling in Xenopus embryos.

76 t process of capacitation, the transition to hyperactivated flagellar motility, develops with a simil

77 We identified hyperactivated focal adhesion kinase (FAK) activity in n

78 lysis has proposed that there may be a third hyperactivated form of ezrin.

79 hey may be related to the stabilization of a hyperactivated form of the enzyme, like in the case of l

80 s not the sole activator of Race, although a hyperactivated form of zen (a zen-VP16 fusion protein) c

81 ntriguingly, loss of fzlA in the presence of hyperactivated FtsWI causes cells to rotate about the di

82 essed endosperm and seed coat regulators and hyperactivated genes encoding ribosomal, photosynthetic,

83 fic sequences were found in the promoters of hyperactivated genes.

84 tism and inflammatory liver cancer caused by hyperactivated GH signaling (GH(tg) ) to mice with hepat

85 ormation of aggressive HCC in the setting of hyperactivated GH signaling.

86 in a pure C57BL/6 background does not induce hyperactivated granulocyte macrophage colony-stimulating

87 ese findings correlated with the presence of hyperactivated helper T cells, which proliferated more v

88 SDH(var+) cells showed stabilized and hyperactivated hypoxia inducible factor (HIF)1alpha sign

89 not of the virus infection per se but of the hyperactivated immune response.

90 s identify a pathway, present in WT mice and hyperactivated in 53BP1-deficient mice, by which microbi

91 unaltered ERK activation but in AKT that was hyperactivated in a BRAF-dependent manner.

92 PARP1 is highly expressed and constitutively hyperactivated in a majority of human CDDP-resistant can

93 It is overexpressed and/or hyperactivated in a variety of cancer cells, thus its in

94 ption 5 (STAT5) is activated by G-CSF and is hyperactivated in acute myeloid leukemia.

95 ase 5 (Cdk5), a critical neuronal kinase, is hyperactivated in AD brains and is, in part, responsible

96 ortantly, similar to lyn(-/-) cells, Fyn was hyperactivated in ASK cells.

97 ion of normal T cells and are constitutively hyperactivated in both HTLV-1-transformed human T cell l

98 ain development and function and is commonly hyperactivated in brain cancer.

99 We found that Src was hyperactivated in brain-seeking breast cancer cells deri

100 udies show that Rac1 GTPase is overexpressed/hyperactivated in breast cancer cells and is associated

101 nistic target of rapamycin (mTOR) pathway is hyperactivated in cancer and neurological disorders.

102 inositol-3-kinase (PI3K) pathway is commonly hyperactivated in cancer.

103 he phosphoinositide 3-kinase/Akt pathway was hyperactivated in cells expressing physiologic levels of

104 Interestingly, we found that when NFkB is hyperactivated in cells with EGFR overexpression and p12

105 ecretions and that this signaling pathway is hyperactivated in CF human, pig, ferret, and mouse SMGs.

106 Akt, mTOR, and their substrates were hyperactivated in colon epithelium of Apcmin/+/Sigirr-/-

107 Functionally, platelets were hyperactivated in COVID-19 subjects presenting non-sever

108 Pak1 is frequently overexpressed and/or hyperactivated in different human cancers, including hum

109 Akt is a key component of this pathway and hyperactivated in different tumors including neuroblasto

110 nd the TGFB and JNK signaling pathways to be hyperactivated in EACs and the genes regulated by these

111 n summary, these data suggest that mTORC2 is hyperactivated in gliomas and functions in promoting tum

112 We show that p42/44 MAPK (ERK1/2) is hyperactivated in hearts derived from Cav-3 knock-out mi

113 ATM/ATR are hyperactivated in hMMS21-RNAi cells upon DNA damage.

114 Upon ionizing radiation, ATM is hyperactivated in HOXB9-expressing cells during the earl

115 EK and JAK/STAT signaling, which is commonly hyperactivated in human and mouse CMML, potently inhibit

116 tors, and lipid signaling, is upregulated or hyperactivated in human breast cancer.

117 The Akt pathway is frequently hyperactivated in human cancer and functions as a cardin

118 Akt is frequently hyperactivated in human cancers and is targeted for canc

119 -activated protein kinases (MAPKs) are often hyperactivated in human cancers, where they affect multi

120 ll survival and proliferation, is frequently hyperactivated in human cancers.

121 K)4 and CDK6 are frequently overexpressed or hyperactivated in human cancers.

122 androgen receptor (AR) is overexpressed and hyperactivated in human castration-resistant prostate ca

123 K1; official name RPS6KA1) was significantly hyperactivated in human melanoma lines and metastatic ti

124 aled that the inflammatory cytokine IL-6 was hyperactivated in IkappaBepsilon(-/-) B cells.

125 Here, we show that NF-kappaB was hyperactivated in in vitro models of OXA-acquired resist

126 The DNA damage response is known to be hyperactivated in late-stage PanINs.

127 Clinically, this PML degradation pathway is hyperactivated in lung cancer and correlates with poor p

128 the beta-catenin signaling pathway which is hyperactivated in many cancers and fibroses.

129 al effector of the ERK signaling pathway, is hyperactivated in many cancers.

130 The PI3K-AKT pathway is hyperactivated in many human cancers, and several drugs

131 abolic pathways and protein synthesis and is hyperactivated in many human cancers.

132 the mammalian target of rapamycin (mTOR) is hyperactivated in many human tumors, including hamartoma

133 ylated by AKT/PKB, a survival kinase that is hyperactivated in many late stage tumors.

134 radation of subcellular constituents that is hyperactivated in many neurodegenerative conditions.

135 he mechanistic target of rapamycin (mTOR) is hyperactivated in many types of cancer, rendering it a c

136 ctor receptor (EGFR) and Torso pathways, are hyperactivated in maternal Rho1 mutants, consistent with

137 mune-modulating kinase, is overexpressed and hyperactivated in MDSs.

138 CDK2 is hyperactivated in multiple cancers and is therefore an a

139 the target of cucurbitacin-I inhibition, was hyperactivated in NF1-deficient primary astrocytes and n

140 ng phosphatase 2 (SHP-2) that is mutated and hyperactivated in Noonan syndrome and a significant port

141 lins and cyclin-dependent kinases (CDKs) are hyperactivated in numerous human tumors.

142 ested the hypothesis that AMPK would also be hyperactivated in O vs YA fast-twitch extensor digitorum

143 Because the AKT-mTOR pathway is frequently hyperactivated in ovarian cancer, we hypothesized that t

144 processes crucial for every living cell, but hyperactivated in overproliferating cells (e.g. cancer t

145 In this report we have shown that mTOR is hyperactivated in Pkd1-null mouse cells due to failure o

146 The PI3K/AKT pathway is hyperactivated in prostate cancer but its effective ther

147 , phosphoinositide 3-kinase/Akt signaling is hyperactivated in Pten conditional knock-out (cKO) retin

148 Here, we surprisingly show that PARP1 is hyperactivated in replicating BRCA2-defective cells.

149 modulator of muscle mass, to be surprisingly hyperactivated in sarcopenic muscle.

150 f rapamycin complex 1 (mTORC1) signaling was hyperactivated in several tissues from Pip4k2c(-/-) mice

151 STAT3 signaling is hyperactivated in SSc in a TGFbeta-dependent manner.

152 Canonical Wnt signaling was hyperactivated in SSc skin biopsy specimens.

153 ssion, and that when the PI3K-Akt pathway is hyperactivated in Teff cells, these cells are resistant

154 ond to astrocyte-derived matrices and become hyperactivated in the Lamc3(-/-) retina or when tested i

155 AT3, AKT, and Wnt/beta-catenin pathways were hyperactivated in the skin and the lungs of diseased mic

156 factor beta (TGF-beta)/SOX6/SOX9 pathway was hyperactivated in the tumor, suggesting that pathways as

157 t of rapamycin complex 1 (mTORC1) pathway is hyperactivated in tissues and tumors derived from LKB1-d

158 ing factor 1alpha (HIF1alpha) is known to be hyperactivated in TNBCs.

159 des promote normal growth and are frequently hyperactivated in tumour cells.

160 g A20-deficient NKT1 and NKT2 thymocytes are hyperactivated in vivo and secrete elevated levels of Th

161 he percentage of reactivated sperm that were hyperactivated increased to 80% when free Ca2+ was incre

162 ter mating allows growth and secretion to be hyperactivated independently of ecdysone levels in SCs,

163 e inactivated and enhancing it when they are hyperactivated, indicative of cells that normally play a

164 These data demonstrate that although hyperactivated IRE1 specifically cleaves BLOC1S1, this c

165 pressed in XBP1-deficient mice livers due to hyperactivated IRE1alpha.

166 a direct consequence, both Akt and Rac1 are hyperactivated, leading to cytoskeletal rearrangements a

167 ion of HES1 and ECM1 in T cell activation is hyperactivated, leading to lymphomagenesis.

168 In the absence of Elp1, Shp1 was hyperactivated, leading to premature TrkA receptor depho

169 des from abnormally low levels to normal pre-hyperactivated levels and, in 20-40% of sperm, induced h

170 growth in the adult CNS at both moderate and hyperactivated levels of ERK1/2 when upregulation commen

171 locus in a snf5Delta mutant and resulted in hyperactivated levels of SUC2 mRNA under inducing condit

172 ic components within the oxPAPC mixture that hyperactivated macrophages, allowing these cells to rele

173 lid tumor and histiocytosis patients, caused hyperactivated MAP kinase signaling, conferred IL-3 hype

174 Conversely, loss of Spry2 function hyperactivated MAPK-ERK signaling and caused increased B

175 In C. elegans, a hyperactivated MEC-4(d) ion channel induces necrotic-lik

176 3T3-L1 transfectants containing hyperactivated MEK1 or overexpressed MAPK displayed impa

177 turnover of the cytoskeletal structures, and hyperactivated mitogen-activated protein kinase signalin

178 in hematopoiesis, it remains unclear whether hyperactivated mitophagy affects the maintenance and dif

179 of the gene encoding the AAA+-ATPase Atad3a hyperactivated mitophagy in mouse hematopoietic cells.

180 Production of hyperactivated motility also required an alkaline enviro

181 el of sperm (CatSper) is essential for sperm hyperactivated motility and fertility.

182 CatSper4 also abrogated ICatSper, sperm cell hyperactivated motility and male fertility but did not a

183 and CatSper2 proteins are critical to sperm-hyperactivated motility and male fertility.

184 ple piece of the sperm tail is essential for hyperactivated motility and male fertility.

185 , pH-sensitive calcium channel essential for hyperactivated motility and male fertility.

186 Sperm cells acquire hyperactivated motility as they ascend the female reprod

187 Ca(2+) entry pathways that support not only hyperactivated motility but possibly also normal pre-hyp

188 motility in the sperm population increasing hyperactivated motility by more than 10-fold as assessed

189 mportant for the sperm to be able to achieve hyperactivated motility in order to reach and fertilize

190 nnel that controls Ca2+ entry to mediate the hyperactivated motility needed late in the preparation o

191 ibited normal motility but could not achieve hyperactivated motility needed to traverse the female ge

192 and the steroid antagonists markedly reduced hyperactivated motility of human sperm assessed by compu

193 ed Ca(2+)-selective channel required for the hyperactivated motility of spermatozoa and male fertilit

194 amplitude flagellar bends characteristic of hyperactivated motility than to produce activated motili

195 ll sperm indicates that a critical lesion in hyperactivated motility underlies the infertility phenot

196 Hyperactivated motility, a swimming pattern of mammalian

197 permatozoa have normal progressive motility, hyperactivated motility, and acrosome reactions.

198 , they acquire progressive motility, develop hyperactivated motility, and are readied for the acrosom

199 Thus, CatSper2 is responsible for driving hyperactivated motility, and, even with typical sperm fo

200 equired for successful fertilization such as hyperactivated motility, chemotaxis, and the acrosome re

201 ases in protein tyrosine phosphorylation and hyperactivated motility, which occur late in capacitatio

202 the null sperm cells is a failure to acquire hyperactivated motility, which seems to render spermatoz

203 onal motion during CatSper channel-dependent hyperactivated motility.

204 Ca(2+) ([Ca(2+)](i)), and the appearance of hyperactivated motility.

205 lators of sperm tail calcium entry and sperm hyperactivated motility.

206 eir spermatozoa lack both Ca(2+) current and hyperactivated motility.

207 re the transition from activated motility to hyperactivated motility.

208 ge role in the initiation and maintenance of hyperactivated motility.

209 -selective current (I(CatSper)) required for hyperactivated motility.

210 ivated motility but possibly also normal pre-hyperactivated motility.

211 ociated with capacitation and development of hyperactivated motility.

212 e model flagellum compare well with data for hyperactivated mouse sperm.

213 for depolarization-evoked Ca2+ entry and for hyperactivated movement, a key flagellar function.

214 These spine deficits correlate with hyperactivated mTOR and impaired autophagy.

215 This crosstalk reveals how hyperactivated mTOR may suppress metastasis locally, whi

216 Recent studies show that hyperactivated mTOR, the 'target of rapamycin' that sens

217 social behavior deficits in ASD models with hyperactivated mTOR.

218 Hyperactivated mTORC1 signaling, an important feature of

219 nhibit ligand binding, and gain-of-function, hyperactivated mutant alphaPS2 proteins cause blistering

220 n as a potential therapeutic strategy in RAS-hyperactivated neuroblastomas.

221 cence response triggered by Tax is caused by hyperactivated NF-kappaB and mediated by cyclin-dependen

222 cient mice accumulate uromodulin, along with hyperactivated NKCC2, resulting in a positive sodium bal

223 s remodeling, including normalization of the hyperactivated p38, in the setting of pre-existing heart

224 e cells to PARP inhibitors is related to the hyperactivated PARP1 in these cells.

225 Interference with the hyperactivated pathways with various pharmacological and

226 nificantly enlarged T cell compartment and a hyperactivated peripheral T cell population.

227 reduced size, abnormal ultrastructure, and a hyperactivated phenotype at steady state, whereas activa

228 Thus, we suggest that the NK hyperactivated phenotype observed in the Noe mice might

229 nction early after treatment and reduces the hyperactivated phenotype proportionally to WAS protein e

230 isingly, Sphk2(-/-) CD4(+) T cells exhibit a hyperactivated phenotype with significantly enhanced pro

231 e few remaining NK cells showed an immature, hyperactivated phenotype, hallmarked by the basal releas

232 Hyperactivated phosphoinositide 3-kinase (PI3K)/Akt seri

233 Hyperactivated PI3K/Akt signaling led to upregulation of

234 and DSB repair, perhaps as a consequence of hyperactivated PI3K/Akt-1 signaling.

235 tion reverses trastuzumab resistance via the hyperactivated PIK/AKT/mTOR pathway due to PTEN loss, by

236 AP) kinase signaling pathway were abnormally hyperactivated prior to the onset of significant cardiac

237 Additionally, the Noe-NK cells were hyperactivated, probably due to increased Helios express

238 n the absence of IL-27R myeloid cells become hyperactivated, produce pro-inflammatory cytokines and a

239 JMML leukemogenesis is linked to a hyperactivated RAS pathway, with driver mutations in the

240 High-risk neuroblastomas with hyperactivated RAS signaling escape the selective pressu

241 How to best contravene hyperactivated RAS signaling has remained elusive in hum

242 ed the amount of GTP-bound, active K-Ras and hyperactivated Ras-ERK1/ERK2 signaling.

243 -jun gene deletion reduced c-Src expression, hyperactivated ROCK II signaling, and reduced cellular p

244 To understand how a hyperactivated RTK functions differently from wild-type

245 In cancer cells, hyperactivated signaling pathways influence translation,

246 Sexed-sperm also revealed significantly less hyperactivated sperm (p < 0.05).

247 ay from a tethering point and consequently a hyperactivated sperm cell bound to an epithelial surface

248 affect the established waveform asymmetry of hyperactivated sperm.

249 The forceful asymmetric motion of hyperactivated spermatozoa requires Ca2+ entry into the

250 ACK2 is enhanced in cells overexpressing the hyperactivated Src(Y527F) mutant.

251 3 dimerization inhibitor capable of blocking hyperactivated STAT3 and suppressing malignant transform

252 Aberrantly hyperactivated STAT3 has been found in human liver cance

253 tination and degradation of LEF-1 protein by hyperactivated STAT5.

254 Like hyperactivated Stat92E, Chinmo misexpression in CySCs is

255 , wg is autonomously repressed in cells with hyperactivated Stat92E.

256 ctivation, cells either pyroptose or enter a hyperactivated state defined by IL-1beta secretion witho

257 mulated with anti-CD28 mAb consistent with a hyperactivated state.

258 plored whether CD151 would mark T cells in a hyperactivated state.

259 Lymphoid and myeloid cells were in a hyperactivated state.

260 ent cations and shift dramatically upward to hyperactivated states with cell signaling in leukocytes.

261 ent cations and shift dramatically upward to hyperactivated states with cell signaling.

262 One form of sepsis, or endotoxic shock, is a hyperactivated systemic response caused by excessive exp

263 le and the CD4Cre transgene contain not only hyperactivated T cells but also develop severe AMF accum

264 The hyperactivated T cells in these mice show defective TCR-

265 is is an inflammatory skin disease caused by hyperactivated T cells regulated by positive and negativ

266 The hyperactivated T cells that develop in these mice have d

267 or the majority of these adverse events is a hyperactivated T-cell response with reactivity directed

268 nover-defective (TD) version, Cdc42pQ61L+TD, hyperactivated the MAPK pathway that regulates filamento

269 stead, myristoylation-incompetent RA T cells hyperactivated the mTORC1 pathway and differentiated int

270 of development, the innate immune system was hyperactivated to a contraproductive level that impaired

271 ned when its downstream effector kinases are hyperactivated to trigger the negative feedback inhibiti

272 ncreased aliphatic glucosinolate content and hyperactivated transcript accumulation of the jasmonic a

273 In a hyperactivated transcriptional coactivator with PDZ-bind

274 lar resonance frequency, at which cells show hyperactivated transcriptional stress responses.

275 edback inhibition of Akt may occur in mTORC1 hyperactivated Tsc-associated tumours.

276 ell subsets: they inhibited T(reg) cells and hyperactivated tumor-infiltrating cytotoxic T lymphocyte

277 d reveal exploitable vulnerabilities of NRF2-hyperactivated tumors.

278 ormal skin lipids that are largely driven by hyperactivated type 2 immune responses.

279 phages from becoming both hemophagocytic and hyperactivated under proinflammation.

280 ERK is hyperactivated upon c-kit signaling in adherent and disp

281 phorylation in ubp8Delta ubp10Delta cells is hyperactivated upon stress, which may compensate for the

282 Hyperactivated variants of the resolvase/invertase famil

283 downstream effector of PTEN is Akt, which is hyperactivated via PTEN inactivation.

284 A mechanical advantage of this hyperactivated waveform has been hypothesized to be the

285 spleens, of diseased 5B6 transgenic mice are hyperactivated when compared with age-matched healthy mi

286 3(25,26,53,54) mutant protein stabilized and hyperactivated wild-type p53, which then inappropriately

287 ther immune and inflammatory pathways become hyperactivated with age and promote degeneration or whet

288 Phagocytic cells hyperactivated with lipopolysaccharide (LPS), which indu

289 extant macrophages and dendritic cells were hyperactivated, with CD11b and GR1 (Ly6G/C) highly expre

290 We have established a Drosophila model with hyperactivated Wnt signaling caused by partial loss of a

291 Many types of human cancers having hyperactivated Wnt signaling display no causative altera

292 d to keep the signaling output "just right." Hyperactivated Wnt signaling due to recurrent genetic al

293 Hyperactivated Wnt signaling increased expression of the

294 isingly, the Overinduced phenotype caused by hyperactivated Wnt signaling is not dependent on signali

295 cient embryos (embryonic day 8.0-8.5) showed hyperactivated Wnt signaling, as well as aberrant differ

296 tion of TAK1 is linked to its suppression of hyperactivated Wnt signaling, evident in both endogenous

297 ing mutation occurs in Apc, which results in hyperactivated Wnt signalling.

298 The hyperactivated Wnt/beta-catenin signaling acts as a swit

299 n, and focal adhesion protein expression via hyperactivated YAP signaling during HF.

300 ugh our previous studies have identified the hyperactivated YAP1 oncogene as a critical contributor t