ライフサイエンスコーパス: hypercoagulable

1 important mediators of the development of a hypercoagulable and prothrombotic state among individual

2 nded in the context of the pro-inflammatory, hypercoagulable background milieu.

3 A striking feature of hypercoagulable conditions is the focal nature of the re

4 nd intestinal function tests and no signs of hypercoagulable disease.

5 should always consider thrombosis and other hypercoagulable diseases in patients with COVID-19.

6 thrombocytopenia (HIT) is an immune-mediated hypercoagulable disorder caused by antibodies to platele

7 aspirin; 5 received warfarin; and 3 (2 whose hypercoagulable disorder was corrected and 1 with sarcoi

8 analyzing the association between inherited hypercoagulable disorders and thrombosis have shown conf

9 so review existing literature of the role of hypercoagulable disorders in arterial thrombosis and dis

10 Acquired hypercoagulable disorders such as heparin-induced thromb

11 to ensure consideration of not only primary hypercoagulable disorders, but also pro-thrombotic medic

12 ous thrombosis and an increased incidence of hypercoagulable disorders.

13 factors in COVID-19 promote an inflammatory hypercoagulable endotheliopathy.

14 rebalanced hemostasis occurs, with distinct hypercoagulable features clinically evidenced by a low r

15 I is associated with both hypocoagulable and hypercoagulable features that can potentially increase t

16 ostasis that include both hypocoagulable and hypercoagulable features.

17 t is suggested that alpha-profibrin may be a hypercoagulable fibrin precursor because it is converted

18 The calculated coagulation index was hypercoagulable in 50% of patients with thromboelastogra

19 rillation (AF), suggesting the presence of a hypercoagulable or prothrombotic state.

20 95, on Holter monitoring in 2 of 192; and on hypercoagulable panel in 30 of 189 patients.

21 romboelastography was defined as two or more hypercoagulable parameters.

22 The hypercoagulable phenotype can be induced in younger chim

23 imaging data show not only the presence of a hypercoagulable phenotype in severe COVID-19 pneumonia b

24 d Protein S deficiency demonstrates that the hypercoagulable phenotype may develop in the recipient o

25 8/14 activates ECs, promotes an inflammatory hypercoagulable phenotype, and is a significant contribu

26 in 43.8% of the population consistent with a hypercoagulable profile.

27 mean age, 27 [16-46] years) had an abnormal hypercoagulable profile.

28 cent of patients had a clotting index in the hypercoagulable range (clotting index > 3) (median 3.05)

29 grees and 72.8 mm, respectively) were in the hypercoagulable range.

30 OR], 5.94 [95% CI, 4.29-8.24]), a hereditary hypercoagulable state (OR, 2.64 [95% CI, 1.32-5.28]), kn

31 actors, including immobilization (P < .001), hypercoagulable state (P = .003), excess estrogen state

32 diagnosed as having Prinzmetal angina and a hypercoagulable state 3 years ago after an ST-elevation

33 (PS) in the context of the development of a hypercoagulable state among individuals with oral squamo

34 ients with severe HIV-tuberculosis display a hypercoagulable state and activation of the endothelium,

35 Surgery precipitates a hypercoagulable state and increases the formation of can

36 nd birth, but invariably succumb to a severe hypercoagulable state and massive thrombosis after 3 wee

37 The mechanisms underlying this hypercoagulable state are complex.

38 urse was complicated by the development of a hypercoagulable state associated with circulating antica

39 ence for the existence of a prothrombotic or hypercoagulable state associated with this disease.

40 ing, whereas later TIC is characterized by a hypercoagulable state associated with venous thromboembo

41 through 1997 revealed 215 patients who had a hypercoagulable state attributed to primary or secondary

42 hemorrhages, which may be associated with a hypercoagulable state caused by COVID-19.

43 om inflammation, endothelial injury, and the hypercoagulable state caused by the injury itself.

44 ns, cofactors, and inhibitors resulting in a hypercoagulable state characterized by enhanced thrombin

45 Pregnancy represents a hypercoagulable state characterized by increased thrombi

46 For patients with a hypercoagulable state corrected by OLT, antithrombotic t

47 No history suggestive of a possible hypercoagulable state could be elicited (she was a nonsm

48 s bleeding complications or development of a hypercoagulable state culminating in life-threatening th

49 IA on platelets and monocytes to propagate a hypercoagulable state culminating in life-threatening th

50 chanisms that contribute to the genesis of a hypercoagulable state during intestinal inflammation rem

51 imulation is pivotal to understanding of the hypercoagulable state found in most cancer patients.

52 and the most common underlying etiology was hypercoagulable state in 30%.

53 hemorheological indices may contribute to a hypercoagulable state in CHF, especially in female patie

54 Several risk factors predispose to the hypercoagulable state in human AF, but whether acute ons

55 In parallel, mechanistic studies of the hypercoagulable state in humans and mouse models implica

56 In vitro coagulation assays demonstrated a hypercoagulable state in obese/T2D mice that was compara

57 y which PF4/heparin antibodies may promote a hypercoagulable state in patients with HITT.

58 The hypercoagulable state in PCOS is not intrinsic to the di

59 ogenesis, and accord with a prothrombotic or hypercoagulable state in this arrhythmia.

60 celerate platelet aggregation resulting in a hypercoagulable state in which the platelet surface beco

61 of infected patients, and it occurs due to a hypercoagulable state induced by the associated inflamma

62 O size, degree of shunting, and a coexisting hypercoagulable state may be additional risk factors.

63 rinogen gamma, a protein associated with the hypercoagulable state of pancreatic cancer, discriminate

64 pression of clfA that is associated with the hypercoagulable state of the host and increased virulenc

65 suggest the preponderant role of a systemic hypercoagulable state over an intrathoracic venous compr

66 age liver disease (ESLD), renal failure, and hypercoagulable state poses a formidable clinical challe

67 Records in 23 patients with a hypercoagulable state related to APC resistance (18 wome

68 addition, PS exposure can play a role in the hypercoagulable state reported to exist in severe beta-t

69 icoagulation or other therapy to control the hypercoagulable state should be given.

70 lieve that severe beta-thalassemia induces a hypercoagulable state that could be partially caused by

71 deficiency has been hypothesized to cause a hypercoagulable state that could induce thrombosis in sm

72 Obesity promotes a chronic inflammatory and hypercoagulable state that drives cardiovascular disease

73 Activation of ECs by aPL may create a hypercoagulable state that precedes and contributes to t

74 wall or blood flow must be associated with a hypercoagulable state to produce thrombosis.

75 VO by 44% (HR, 1.44; 95% CI, 1.23-1.68), and hypercoagulable state was associated with a 145% increas

76 rombosis was documented in 9 patients, and a hypercoagulable state was identified in 10.

77 Stroke risk factors or other causes of a hypercoagulable state were found in 12 patients.

78 ce of antiphospholipid syndrome and no other hypercoagulable state were included if the observed thro

79 events in the context of a pro-inflammatory hypercoagulable state with elevated C-reactive protein,

80 BP patients are usually in a hypercoagulable state with increased levels of D-dimer a

81 liver cirrhosis (LC) behaves as an acquired hypercoagulable state with increased thrombotic risk.

82 d 136 patients (11.5%) were diagnosed with a hypercoagulable state within 1 year after CRVO diagnosis

83 testing, 5.9% (43/731) were diagnosed with a hypercoagulable state within 1 year compared with 20.7%

84 The prevalence of a hypercoagulable state within 1 year of CRVO diagnosis in

85 upport would be prohibitively risky due to a hypercoagulable state, a contraindication to anticoagula

86 Neither is believed to generate a hypercoagulable state, although both may exacerbate pre-

87 nt cell arteritis, carotid stenosis, stroke, hypercoagulable state, and DM with ophthalmic complicati

88 A hypercoagulable state, chronic inflammation, and increas

89 ssessed included immobilization, malignancy, hypercoagulable state, excess estrogen state, a history

90 onary embolism, peripheral vascular disease, hypercoagulable state, myocardial infarction) or anticoa

91 he proteomic footprint of POTS in terms of a hypercoagulable state, proinflammatory state, enhanced c

92 To investigate the etiology of this hypercoagulable state, we have used the Russell's viper

93 lity of band 3 null mice may be related to a hypercoagulable state, which appears to originate from c

94 normalities contribute to a prothrombotic or hypercoagulable state, which increases the risk of throm

95 lation is associated with a prothrombotic or hypercoagulable state, which may contribute to an increa

96 G-CSF induces a hypercoagulable state, which may predispose certain dono

97 EG demonstrated that both developed a marked hypercoagulable state, which was treated with low-molecu

98 r disease risk factors and other causes of a hypercoagulable state.

99 activated protein C and leads to a relative hypercoagulable state.

100 se nature of the atherosclerotic disease and hypercoagulable state.

101 is believed to be the cause of the patient's hypercoagulable state.

102 SARS-CoV-2) infection is associated with the hypercoagulable state.

103 stasis, notably a progressive tilt towards a hypercoagulable state.

104 esistance, dyslipidemia, inflammation, and a hypercoagulable state.

105 in cultured EC, and contribute to UA-induced hypercoagulable state.

106 Pregnancy is associated with a hypercoagulable state.

107 otein synthesis subsequently contribute to a hypercoagulable state.

108 w that coronavirus disease 2019 results in a hypercoagulable state.

109 of other risk factors, may contribute to the hypercoagulable state.

110 and that a defective clearance can induce a hypercoagulable state.

111 atic and clinical factors contribute to this hypercoagulable state.

112 s have an increased risk of VTE because of a hypercoagulable state.

113 sociated with the generation of an intrinsic hypercoagulable state.

114 A subset of patients was evaluated for hypercoagulable state.

115 lling the requirement for a prothrombotic or hypercoagulable state.

116 olycystic ovary syndrome (PCOS) women have a hypercoagulable state; however, whether this is intrinsi

117 Are ESRD patients with hypercoagulable states (HCS) (antithrombin III deficienc

118 ertension (HR = 1.62; 95% CI: 1.26-2.07) and hypercoagulable states (HR = 2.46; 95% CI: 1.51-4.00).

119 Congenital and acquired hypercoagulable states are reviewed here, with an emphas

120 Congenital and acquired hypercoagulable states arise from an imbalance between p

121 ce has implicated the two most common venous hypercoagulable states in ischemic heart disease.

122 nfectious, and post-infectious encephalitis, hypercoagulable states leading to stroke, and acute neur

123 Noncirrhotic patients with hypercoagulable states tend to develop PB when PVT exten

124 recommended in conditions of blood stasis or hypercoagulable states that mostly result in red thrombi

125 Hypercoagulable states were demonstrated in most episode

126 Hypercoagulable states were found upon reevaluating five

127 Hypercoagulable states were prospectively detected in 10

128 ion, diabetes, glaucoma, obesity, underlying hypercoagulable states, and those requiring intubation d

129 e apply the model to two clinically relevant hypercoagulable states, caused by deficiency of either a

130 ncluding virus-induced hyperinflammatory and hypercoagulable states, direct virus infection of the ce

131 iovascular pathology intricately linked with hypercoagulable states, notably malignancy and autoimmun

132 ests for a variety of inherited and acquired hypercoagulable states, were carried out.

133 s-based vaccines or if it could worsen known hypercoagulable states.

134 ension, hemoconcentration, hemodilution, and hypercoagulable states.

135 was observed in anticoagulated patients with hypercoagulable states.

136 ctically anticoagulating study patients with hypercoagulable states.

137 echanisms including hyperreactive platelets, hypercoagulable status, and endothelial dysfunction.

138 hy performed and 58% of these patients had a hypercoagulable study.

139 d abnormal coagulation markers, suggesting a hypercoagulable subphenotype.

140 is used, clinicians should be aware of this hypercoagulable syndrome.

141 Antithrombin III deficiencies and hypercoagulable TEG parameters were prevalent among pati

142 mbin III and anti-Factor Xa deficiencies and hypercoagulable TEG parameters, including elevated coagu

143 ADAMTS-13 was an independent predictor of a hypercoagulable TEG profile and platelet count, endotoxi

144 rch should examine the usefulness of uniform hypercoagulable testing in young CRVO patients.

145 elieve younger women with SVT should undergo hypercoagulable testing to identify the need for long-te

146 were men, 450 patients (38.1%) had undergone hypercoagulable testing within 90 days, and 136 patients

147 s; mean age, 32 [16-61] years) had undergone hypercoagulable testing.

148 patients with coronavirus disease 2019 have hypercoagulable thromboelastography profiles with additi

149 Hypercoagulable thromboelastography was defined as two o

150 who received 34 mg/m(2) were treated after a hypercoagulable work-up to exclude potential risk factor

151 ents with cirrhosis and PVT do not require a hypercoagulable workup in the absence of additional thro

152 ipient (four of seven patients with positive hypercoagulable workup).