戻る
「早戻しボタン」を押すと検索画面に戻ります。 [閉じる]

コーパス検索結果 (１語後でソート)

通し番号をクリックするとPubMedの該当ページを表示します
1 c mutations in its Brd and GY boxes exhibits hypermorphic activity that results in characteristic def
2 1(Pro) alleles is not consistent with simple hypermorphic activity.
3                               In contrast, a hypermorphic allele of T-bet can reverse silencing of th
4 ssion of TEC1, by expression of the dominant hypermorphic allele STE11-4 or by deletion of HOG1, Ty1
5 ay inform future gene-editing strategies for hypermorphic alleles and have advanced the pursuit of ge
6            Screens for suppressors of lin-12 hypermorphic alleles in C. elegans have identified core
7          The most prevalent suppressors were hypermorphic alleles of dgkB, which encodes a soluble di
8 e identified three of four such mutations as hypermorphic alleles of Gnaq and Gna11, which encode wid
9 ors of the egg-laying defect associated with hypermorphic alleles of lin-12.
10 tains its potency against yeast carrying the hypermorphic alleles PDR1-11 or PDR1-3.
11 ) to chronic mucocutaneous candidiasis (CMC; hypermorphic alleles).
12 st, a common T108M polymorphism in GPR35 was hypermorphic and had the opposite effects to Gpr35 delet
13            Constitutively active mutants are hypermorphic as they trigger proliferation and death mor
14 vo, resulting in phenotypic suppression of a hypermorphic bin2 mutation and enhanced resistance to a
15 liogenesis and report that mutant Htt causes hypermorphic ciliogenesis and ciliary dysfunction.
16 atient we identified two rare, recessive and hypermorphic coding variants in GPATCH3, a gene of unide
17 n mutations enhance hypomorphic and suppress hypermorphic D-ERK mutant phenotypes.
18 aracterization in patients' blood revealed a hypermorphic effect of this Sp1 variant, triggering supe
19 l and histologic analyses established if the hypermorphic Egfr(Dsk5) allele can rescue the woe embryo
20                       S703I JAK1 is not only hypermorphic for cytokine signaling but also neomorphic,
21       We propose that the Rad50(S) allele is hypermorphic for DNA damage signaling, and that the resu
22 ified as a dominant suppressor of EgfrElp, a hypermorphic form of the Drosophila Epidermal growth fac
23  suggest that CLN4 alleles resemble dominant hypermorphic gain of function mutations that drive exces
24 s were likely caused by either neomorphic or hypermorphic gain-of-function mutations in the BIN2 gene
25 lele can be spatiotemporally switched to the hypermorphic H allele by Cre-loxP recombination.
26           cis-acting composite mutations are hypermorphic in some genes in which dosage effects predo
27 rmant studies confirmed that the mutation is hypermorphic in vivo, but the DER function was elevated
28  with previous results, PLCG2(R665W) confers hypermorphic induction of downstream signaling events.
29                         Here we analyze Pten hypermorphic mice (Pten(hy/+)), expressing 80% normal le
30 Here we show that a previously characterized hypermorphic mutant FtsA (FtsA*) partially disassembled
31                               In contrast, a hypermorphic mutant of FtsA (FtsA*) forms mainly arcs in
32 hed using an anergy model in which the Zap70 hypermorphic mutant W131A is coexpressed with the OTII T
33 ome (BAC)-based transgenic system in which a hypermorphic mutation has been introduced into the murin
34                                          The hypermorphic mutations are also associated with arterial
35     A study of drug-resistant lymphomas with hypermorphic mutations in PRC2 has identified a 'methyla
36 morphic mutations in STAT3 and patients with hypermorphic mutations in STAT1 share several clinical a
37                Drug addiction is mediated by hypermorphic mutations in the CXC domain of the catalyti
38                                              Hypermorphic mutations in the Wnt co-receptor LRP5 sugge
39 5F be referred to as allomorphic rather than hypermorphic mutations of PLCG2 Rerouting of the transme
40 m of fixation in the presence of amorphic or hypermorphic mutations, we consider a diallelic model at
41 ral vector to drive expression of wild-type, hypermorphic, or hypomorphic MYC in bone marrow that exp
42                                      The p53 hypermorphic (p53+/m) mice display phenotypes of prematu
43 ,C186S) not targeted to membranes produced a hypermorphic phenotype and stimulated mitogen-activated
44                                        These hypermorphic phenotypes could be relieved by deleting mo
45 the highly conserved Lys-774 residue induced hypermorphic phenotypes that mimicked the loss of phosph
46 ons of this cleavage site produced the first hypermorphic point mutation within the Apaf1/Ced-4 gene
47                                          The hypermorphic Rad50(S) allele encodes a variant of Rad50,
48           Hematopoietic cells expressing the hypermorphic Rad50(s) allele show hematopoietic failure,
49        We report the positional cloning of a hypermorphic, regulatory mutation in Fpn1 from radiation
50 ress, was evoked in zebrafish expressing the hypermorphic Ser482Cys-GLS and could be alleviated by in
51                   A previously characterized hypermorphic sir3 mutation, D205N, greatly improves sile
52 vide insights into the mechanisms underlying hypermorphic SPOP mutations.
53 xpress oncogenic Kras and null, wild-type or hypermorphic Trp53 alleles in alveolar type 2 (AT2) cell
54                 Here, we analyze mice with a hypermorphic Zap70 mutation, W131A, which destabilizes t