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1 nt cells, and we mapped this activity to the hypervariable region.
2 obility analysis of the second envelope gene hypervariable region.
3 ha and Vbeta chain usage, and throughout the hypervariable region.
4 ed flanking domains and the other within the hypervariable region.
5 r more p44 species were found within the p44 hypervariable region.
6 racterized by conserved sequences flanking a hypervariable region.
7 y charged lysine at position 12 of the first hypervariable region.
8 A gene sequences by more than 80% for the V4 hypervariable region.
9 id pattern as well as a distinctive 16S rRNA hypervariable region.
10 ed except for sequence that encoded the MSP2 hypervariable region.
11 lyzed using 16S rRNA sequencing of the V3-V4 hypervariable region.
12 arnesylated-methylated KRAS4b, including the hypervariable region.
13 in the conserved positions, and GS"N in the hypervariable regions.
14 regions, including splice site acceptors and hypervariable regions.
15 S rRNA gene primer sets, targeting different hypervariable regions.
16 imilar magnitude were found in conserved and hypervariable regions.
17 have the same canonical structures in their hypervariable regions.
18 anonical structure in their first and second hypervariable regions.
19 not exclusively, directed against the hexon hypervariable regions.
20 is is further complicated by the presence of hypervariable regions.
21 of hepatitis C virus (HCV) contains several hypervariable regions.
22 Viral quasispecies in the second envelope hypervariable region 1 (E2/HVR1) and 5' untranslated reg
24 amino acid quasispecies complexities of the hypervariable region 1 (HVR-1) were less in the responde
26 edly reduced binding when amino acids within hypervariable region 1 (HVR1) and at sites approximately
30 HCV internal ribosomal entry site (IRES) and hypervariable region 1 (HVR1) in autopsy-derived brain,
34 which we find maps to a specific site within hypervariable region 1 (HVR1) of AdV5 hexon, has no appa
35 f HCV and shielding of important epitopes by hypervariable region 1 (HVR1) of E2 are believed to be m
41 to Huh7.5 cells to produce a quasispecies of hypervariable region 1 (HVR1) that mimicked that circula
44 notype-specific epitopes of HCV core, E1, E2 hypervariable region 1 (HVR1), E2 HVR1-plus-HVR2 consens
45 of cDNA that spanned the E1 gene and the E2 hypervariable region 1 (HVR1), followed by analysis of c
48 1a)/JFH1 or the highly antibody-susceptible hypervariable region 1 (HVR1)-deleted variants H77/JFH1D
49 tify AR3A resistance substitutions that have hypervariable region 1 (HVR1)-dependent effects on HCV v
50 that major outer membrane protein 1 (OMP-19) hypervariable region 1 (HVR1)-specific human monoclonal
55 d, ranging from high diversity (the envelope hypervariable region 1 [HVR1]) to almost no diversity (t
56 te populations, we compared mtDNA (400 bp of hypervariable region 1 and 14 restriction site polymorph
57 alizing epitopes on the E1 N-terminus and E2 hypervariable region 1 did not differ significantly.
58 h relapse were virtually identical, with the hypervariable region 1 of E2 appearing to be monoclonal,
59 on of SR-BI governed by specific residues in hypervariable region 1 of E2 leading to enhanced cell en
62 Next-generation sequencing data from the hypervariable region 1 of HCV were analyzed using Global
63 is virus (VSV)/HCV pseudotype model that the hypervariable region 1 of the HCV E2 envelope glycoprote
64 o 986 present-day human sequences located in hypervariable region 1 of the mitochondrion to estimate
67 equence revealed amino acid substitutions in hypervariable region 1 that were responsible for a drama
68 yethylene glycol to a specific site in hexon hypervariable region 1 yielded vector particles that wer
70 so generated serological responses to OMP-1g hypervariable region 1, indicating that humans and mice
71 cases, correlate also with antibodies to the hypervariable region 1, previously thought to be the pri
72 s, suggesting purifying selection, except in hypervariable region 1, where positive selection pressur
73 for immunogenicity in mice, with and without hypervariable region 1, which is an immunogenic region a
76 lotype analysis and direct sequencing of the hypervariable regions 1 and 2 of the D-loop in muscle an
77 tes microbial communities, but sequencing of hypervariable regions 1-3 of the 16S rRNA gene provides
81 a single immunization of chimeric rAd5 hexon hypervariable region 48 (rAd5HVR48) vectors expressing S
82 igen (PA) as a model antigen to characterize hypervariable region 5 (HVR5) of hexon as a site for pep
84 l with mutations in the surface glycoprotein hypervariable regions: a previously identified variant c
85 e for viral replication, and the nsp2 middle hypervariable region (aa 324 to 813) tolerated 100-aa or
86 MiSeq and Roche454 platforms using the V3-V4 hypervariable region also showed a high level of concord
87 oximately 30 to 35 kDa consisting of several hypervariable regions alternating with conserved regions
88 ue to a mixture of P44 proteins with diverse hypervariable region amino acid sequences expressed by a
89 kines was localized to 40 amino acids in the hypervariable region (amino acids 301-340) of the protei
91 membrane but is tethered via its C-terminal hypervariable region and carboxymethylated farnesyl moie
93 hanges both within the traditionally defined hypervariable regions and downstream, near the 3'-end of
94 sing from the crystal structure that include hypervariable regions and the epitope of a neutralizing
95 ure as determined via 18S rRNA (V4 and V8-V9 hypervariable regions) and 16S rRNA (V1-V3) gene amplico
96 creased frequency of B cells with long third hypervariable regions, and distal J(kappa) gene segment
97 r multiple markers such as the 16S rRNA gene hypervariable regions are available, MetAmp improves the
100 e, and -f were mapped within the nsp2 middle hypervariable region, but no conserved cleavage sites co
101 ive RNA splicing primarily in its N-terminal hypervariable region, but the functions of these isoform
104 the second constant region through the fifth hypervariable region (C2 to V5) of the surface envelope
106 ith bNAb sensitivity, including amino acids, hypervariable region characteristics, and clade effects
107 ts and the genes from the other intraspecies hypervariable regions contributes to a better assessment
112 monella typhimurium phase 1 flagellin, this "hypervariable" region encodes two solvent-exposed domain
113 cally infected individuals by sequencing the hypervariable regions encoding TCR alpha and beta polype
114 lysis indicated that most sites outside this hypervariable region experienced strong negative selecti
116 se pseudogenes encode unique surface-exposed hypervariable regions flanked by conserved domains, whic
117 extension containing a His- and Asp/Glu-rich hypervariable region followed by a highly conserved sequ
118 identified in at least two of five examined hypervariable regions for every virus, suggesting the ev
119 d for identification of the 16S rRNA gene V3 hypervariable region from Escherichia coli genomic DNA.
121 g it into our Ad5 vector containing all nine hypervariable regions from Ad43, Ad5.H(43m-43), increase
122 m TRUST to extract the B cell immunoglobulin hypervariable regions from bulk tumor RNA-sequencing dat
123 the specific amplification of 18s rRNA gene hypervariable regions from eukaryotic microbes: anneal-i
124 two primer pairs demonstrated that the V3-V4 hypervariable region had significantly better capture of
125 etion variants of UreG demonstrated that the hypervariable region has a minor impact on activation ef
126 by the novel gene p44-61 (p44-61/18), whose hypervariable region (hv) was a chimera of p44-20hv and
129 face protein 2 (MSP2), composed of a central hypervariable region (HVR) flanked by highly conserved r
130 me of the hepatitis E virus (HEV) contains a hypervariable region (HVR) in ORF1 that tolerates small
131 simulations highlight that the membrane and hypervariable region (HVR) interact with both alpha- and
132 rnesylated and positively charged C-terminal hypervariable region (HVR) is critical to its oncogenic
133 sed on chromosomal DNA fingerprints (CDF), a hypervariable region (HVR) of a 5.6-kb plasmid, the rRNA
135 man ribosomal protein S17 (RPS17) within the hypervariable region (HVR) of the HEV ORF1 protein.
137 n, predominately against the surface-exposed hypervariable region (HVR) rather than against the invar
139 Comparative sequence analysis revealed a hypervariable region (HVR) with extensive sequence varia
140 st distribution of polymorphisms occurs in a hypervariable region (HVR) within the carboxy third of t
141 cently, insertions and rearrangements of the hypervariable region (HVR) within the HEV genome, allowi
142 -Ras4B is predominantly autoinhibited by its hypervariable region (HVR), whereas the GTP-bound state
144 of the HCV envelope gene including the first hypervariable region (HVR-1) was reverse transcription-P
147 quence diversity and complexity at the first hypervariable region (HVR1) of the second envelope prote
149 ing antibodies typically recognize M protein hypervariable regions (HVRs) and confer narrow protectio
150 at CaM preferentially binds unfolded K-Ras4B hypervariable regions (HVRs) and not alpha-helical HVRs.
151 h substantial sequence homology in the hexon hypervariable regions (HVRs) and suppressed the immunoge
154 maeric rAd5 vectors in which the seven short hypervariable regions (HVRs) on the surface of the Ad5 h
155 us catalytic domains and flexible C-terminal hypervariable regions (HVRs) that differ across Ras isof
156 amino acid sequence variations confirms four hypervariable regions (HVRs), separated by regions under
162 60 million molecules) of human mitochondrial hypervariable region II amplicon was introduced into the
163 Here we show that the human mitochondrial hypervariable region II can function as a molecular fing
164 esent high-throughput sequencing analysis of hypervariable region II for spatial resolution of the co
165 the structural and physiological role of the hypervariable region in flagella assembly, stability and
167 on-typeable H.influenzae isolates revealed a hypervariable region in the central portion of the mod g
168 e induction of Gal-3 expression requires the hypervariable region in the extracellular domain of beta
170 oci within A. lyrata, sites corresponding to hypervariable regions in the Brassica S-loci (SLG and SR
174 conversion of the entire (nonsegmental) p44 hypervariable region including flanking regions with a c
176 sitive to GM-CSF, mutations within the N-Ras hypervariable region induced N-Ras mislocalization and a
178 differences in the primary sequences of the hypervariable region manifest in different secondary str
179 genomic expression site encoding the central hypervariable region matched sequence polymorphisms in m
180 in primary structure within the immunogenic hypervariable region microdomains and tested whether the
181 QA1*0501, and DRB1 alleles sharing the first hypervariable region motif (9)EYSTS(13) were major risk
182 ted nanoclustering of H-ras helix alpha4 and hypervariable region mutants that have different bona fi
183 S ribosomal RNA amplicon sequences in the V4 hypervariable region obtained from 492 studies worldwide
185 .1 M bacterial pyrotag sequences from the V6 hypervariable region of 16S rRNA genes from 38 influent
186 human hepatoma cells when inserted into the hypervariable region of a genotype 1 strain, but this ch
187 g a shift from recombination of the complete hypervariable region of a given pseudogene to complex mo
189 s recovered, 39 recognized an amino-terminal hypervariable region of an outer membrane protein (OMP),
192 a crucial but commonly coded residue in the hypervariable region of CDR3 provide the basis for the s
193 anged p44Es revealed that the entire central hypervariable region of donor p44 pseudogenes or of dono
194 rough elevated signal produced to the unique hypervariable region of each - 2/114 in HL-60, 3/114 in
199 tration calorimetry, we demonstrate that the hypervariable region of K-Ras4B contributes in a major w
200 nce for four short sequential changes in the hypervariable region of msp2 coupled with the identifica
201 histocompatibility antigens, we examined one hypervariable region of mtDNA, designated hypervariable
206 r results show that in the murine model, the hypervariable region of PilE is required to activate imm
207 nal structure-based antigen by replacing the hypervariable region of PilE with an aspartate-glutamine
208 ly bound to the CAAX motif in the C-terminal hypervariable region of Rac1, and then inhibited Rac1 me
209 ow that elements in the known domains in the hypervariable region of Ras (amino acids 170-189) intera
214 zed by bar-coded pyrosequencing of the V3-V5 hypervariable region of the 16S rRNA gene, defining 662
215 ent study, using pyrosequencing of the V1-V2 hypervariable region of the 16S rRNA gene, reported find
216 Our study included the analysis of the D1/D2 hypervariable region of the 28S ribosomal gene and the i
219 idase subunit 1 gene of nematodes and the V3 hypervariable region of the bacterial 16 s ribosomal RNA
220 d a tag-sequencing strategy targeting the V6 hypervariable region of the bacterial small-subunit (16S
221 ndings indicate that sequence variation in a hypervariable region of the degron affects JAZ stability
222 relatively small genomic segment, the first hypervariable region of the E2 gene, it is possible that
223 manifestations of disease are clustered in a hypervariable region of the genome termed the plasticity
224 rminants of macrophage infectivity to the V3 hypervariable region of the HIV-1 envelope glycoprotein.
226 This residue is located in the C-terminal hypervariable region of the proteins and is not conserve
229 nd ESPRIT-Tree, sequence data from different hypervariable regions of 16S rRNA were used and binning
230 cultures of strains NY-31, NY-36, and NY-37, hypervariable regions of 450 deduced amino acid sequence
231 serotype 5 (Ad5) vector containing the hexon hypervariable regions of Ad serotype 48 (Ad48) and expre
232 hexon-modified vector that carried the hexon hypervariable regions of Ad48, indicating that the SP mu
235 Finally, features of the first and second hypervariable regions of gp120 (V1V2) may be critical fo
237 oes is efficiently surveyed by sequencing of hypervariable regions of the 16s ribosomal RNA (rRNA) ge
238 lyzed by FLX+ pyrosequencing of the V1 to V4 hypervariable regions of the 16S rRNA gene and polymeras
239 Unique melt profiles generated from multiple hypervariable regions of the 16S rRNA gene for 100 clini
240 dot blot hybridization, by sequences of two hypervariable regions of the 16S rRNA gene, and by the p
241 DNA was amplified with primer pairs covering hypervariable regions of the 16S rRNA gene: primers 63F
242 iversity of sequence, primarily localized to hypervariable regions of the capsid protein, was detecte
245 ensic identity testing by sequencing the two hypervariable regions of the human mtDNA control region.
246 Conventional genotyping methods target small hypervariable regions of the M. bovis genome and provide
248 ences between D1 domains are concentrated in hypervariable regions on the front sheet strands of the
249 bit antisera raised against either the first hypervariable region or ectodomain of E2 showed limited
250 several single-nucleotide substitutions in a hypervariable region outside the SAM-binding core can al
251 g GC and AT rich motifs correlated well with hypervariable region recombination sites across the HAdV
254 quences follows the pattern of conserved and hypervariable regions seen in other S-RNases, but no reg
257 elope protein (Env) by replacing part of its hypervariable region sequence with a sequence encoding t
258 ing more than 1.7 million bacterial 16S rRNA hypervariable region sequences from 52 to 56 samples per
259 Results obtained from the V3-V4 16S rRNA hypervariable region, sequencing on the MiSeq and Roche4
260 in the plasma membrane via lipid-tethers and hypervariable region side-chain interactions in distinct
262 method also identified 18 other intraspecies hypervariable regions, such as the capsule and lipooligo
263 key changes to the lipidation pattern of the hypervariable region, suggest that dimerization is a gen
264 ermini flanking the central, surface-exposed hypervariable region that represents the variant B lymph
265 n that all serotypes have in common from the hypervariable regions that are responsible for capsid di
267 ferences between RAS isoforms lie within the hypervariable region, the additional confinement of KRAS
268 mice, suggesting that in the absence of the hypervariable region, the conserved regions of PilE alon
270 a gonorrhoeae and contains a surface-exposed hypervariable region thought to be one feature of pili t
271 s in the mtDNA control region, including the hypervariable regions typically sequenced in a forensic
272 existence of a conserved region linked to a hypervariable region upstream of the 16S rRNA gene of H.
273 two species by pyrosequencing the 16S V1-V3 hypervariable regions using the 454 GS FLX Titanium plat
274 pected microbial profiles, sequencing of the hypervariable regions V1-V3 of the 16S ribosomal RNA gen
275 Previous studies have shown that the first hypervariable region (V1 loop) is immunogenic on soluble
276 ies (NAbs) that primarily targeted the first hypervariable region (V1 loop) of gp120, although SF162g
277 to potential N-linked glycosylation sites in hypervariable regions (V1 to V3) of the env gene of HIV
278 lope glycoproteins, the presence of all five hypervariable regions (V1 to V5) was required for optima
280 n reaction was performed to amplify 16S rRNA hypervariable region V3-V4, and constructed libraries we
282 had greater accuracy than sequencing of the hypervariable region V4 in determining genus and species
286 ehrlichiosis (HGE) with primers flanking the hypervariable region, we show differential expression in
289 Sequence diversities in the G protein second hypervariable region were observed in the duplicated reg
291 d by genetic manipulation of the murine CC49 hypervariable regions were evaluated for their relative
294 ting phage binding were located in these two hypervariable regions, which are likely to be exposed on
295 analysis indicates that alternative 16S rRNA hypervariable regions will present similar challenges, w
297 -DR alleles sharing amino acids at the third hypervariable region with DRB1*0401(shared epitope) are
299 s identified as phage morons were located in hypervariable regions within individual SVMs, indicating