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1 nction, delayed puberty and hypogonadotropic hypogonadism).
2 f the hypothalamic-pituitary unit (secondary hypogonadism).
3 ads to a strong meiotic phenotype and severe hypogonadism.
4 tigate the pathogenesis of hypogonadotrophic hypogonadism.
5 unctions absent in patients with hypogonadal hypogonadism.
6 um criteria necessary to identify late-onset hypogonadism.
7 exhibit subfertility due to hypogonadotropic hypogonadism.
8 g recognized in males and is associated with hypogonadism.
9 erlapping features of impaired olfaction and hypogonadism.
10 he rare adult-onset form of hypogonadotropic hypogonadism.
11 ransplant recipients should be evaluated for hypogonadism.
12 and delayed puberty due to hypogonadotropic hypogonadism.
13 germ cells to progress through meiosis I and hypogonadism.
14 ced effect on the prostate in a rat model of hypogonadism.
15 the hypothalamus as well as hypogonadotropic hypogonadism.
16 SHR) null mice have bone loss despite severe hypogonadism.
17 ivation therapy (ADT), resulting in profound hypogonadism.
18 loss of sense of smell and hypogonadotrophic hypogonadism.
19 y adrenal insufficiency and hypogonadotropic hypogonadism.
20 hormone replacement therapy as indicated for hypogonadism.
21 lative effect of estrogen status compared to hypogonadism.
22 d primary hypogonadism and two had secondary hypogonadism.
23 sk of prostate cancer in men with late-onset hypogonadism.
24 beta gene, which causes Q54 to be R, causes hypogonadism.
25 roduce less testosterone, leading to primary hypogonadism.
26 e intervention in older men with obesity and hypogonadism.
27 upted vaginal cycling, and hypergonadotropic hypogonadism.
28 myelination, hypodontia and hypogonadotropic hypogonadism.
29 oidism, hypoadrenalism, and hypogonadotropic hypogonadism.
30 me a promising prospect for treating primary hypogonadism.
31 ed body mass, reduced physical activity, and hypogonadism.
32 d if dysfunctional leads to Hypogonadotropic Hypogonadism.
33 y, intellectual disability, polydactyly, and hypogonadism.
34 ase, although it is often in part related to hypogonadism.
35 ann syndrome and idiopathic hypogonadotropic hypogonadism.
36 oportionate short stature, microcephaly, and hypogonadism.
37 ypothalamic amenorrhea, and hypogonadotropic hypogonadism.
38 rrhea, hypothyroidism, and hypergonadotropic hypogonadism.
39 a, uterine hypoplasia, and hypergonadotropic hypogonadism.
40 health in relation to testosterone and male hypogonadism.
41 aracterized by anosmia and hypogonadotrophic hypogonadism.
42 ctions, such as potency and libido, to avoid hypogonadism.
43 cts of the medications as opposed to chronic hypogonadism.
44 sk of prostate cancer in men with late-onset hypogonadism.
45 and pubertal failure due to hypogonadotropic hypogonadism.
46 range and reported no increased symptoms of hypogonadism.
47 g ADT and in elderly men with age-associated hypogonadism.
48 steoporosis caused by chronic opioid-induced hypogonadism.
49 hs, that underlies typical hypogonadotrophic hypogonadism.
50 rophin deficiency known as hypogonadotrophic hypogonadism.
51 unction of the reproductive axis and causing hypogonadism.(1-4) Thirteen-lined ground squirrels (Icti
53 bnormal reproductive hormones: 4 had primary hypogonadism, 2 had secondary hypogonadism, and 1 develo
54 D] body mass index, 33.5 [7.3]), 116 men had hypogonadism, 427 had eugonadism, and 180 were receiving
55 ta suggest that in aging men with late-onset hypogonadism, 6 months of TRT normalizes serum androgen
56 enes involved in idiopathic hypogonadotropic hypogonadism, a congenital form of GnRH deficiency, are
57 of GPR54 causes idiopathic hypogonadotropic hypogonadism, a disorder characterized by delayed pubert
59 hormonal changes were simulated by inducing hypogonadism, adding back estradiol (E2) and progesteron
60 nsipidus, growth hormone deficiency, primary hypogonadism, adrenal insufficiency, and hypothyroidism.
63 mong 50 men with idiopathic hypogonadotropic hypogonadism after a mean (+/-SD) duration of treatment
64 y hyperphagia, obesity and hypogonadotrophic hypogonadism, all highly suggestive of hypothalamic dysf
70 include Kallmann syndrome (hypogonadotropic hypogonadism and anosmia), stereotyped midface hypoplasi
71 drome, a condition characterized by obesity, hypogonadism and behavioral abnormalities, the expressio
75 mild of form of FA-like phenotypes including hypogonadism and cellular sensitivity to the crosslinker
76 reminiscent of isolated LH-hypogonadotropic hypogonadism and corpus luteum insufficiency in humans.
77 pectrum of endocrine abnormalities including hypogonadism and feminization, with elevated serum estra
82 ascular disease and who reported symptoms of hypogonadism and had two fasting testosterone levels of
86 ic hypogonadism (IHH) is a rare disease with hypogonadism and infertility caused by the defects in em
88 treatment of CFRD, CFBD, growth and puberty, hypogonadism and infertility, iatrogenic adrenal insuffi
93 cross-sectional study examines prevalence of hypogonadism and its correlation with QoL and sexual dys
100 in an individual with hyperphagia, obesity, hypogonadism and other features associated with PWS, whi
102 metabolic syndrome, cardiovascular disease, hypogonadism and psychosocial issues, and might yield gr
104 ssive loss of male fertility, accompanied by hypogonadism and seminal vesicle agenesis/hypodysplasia.
107 ith CSF measures of androsterone during both hypogonadism and testosterone replacement (r = -0.76 and
108 sal of normosmic idiopathic hypogonadotropic hypogonadism and the Kallmann syndrome was noted after d
109 ression models to examine the association of hypogonadism and time to depression diagnosis, adjusting
111 4 had primary hypogonadism, 2 had secondary hypogonadism, and 1 developed hyperestrogenemia with ele
112 rain anomalies, heart defects, macrocephaly, hypogonadism, and additional features with variable expr
113 g resolution of type 2 diabetes mellitus and hypogonadism, and beneficial effects on ingestive and no
114 published studies relating to testosterone, hypogonadism, and HF and provide practical clinical info
115 e molecular mechanisms of vascular injury in hypogonadism, and identify hypospadias as a cardiovascul
116 which includes hyperphagia, severe obesity, hypogonadism, and impaired immunity, has provided insigh
125 tional risk factors such as low body weight, hypogonadism, and smoking, as well as direct effects of
127 diovascular disease; one or more symptoms of hypogonadism; and two morning testosterone concentration
129 associated with idiopathic hypogonadotropic hypogonadism are found in women with hypothalamic amenor
130 mutants from patients with hypogonadotropic hypogonadism are frequently misrouted proteins that exer
132 g body of evidence suggests the role of male hypogonadism as a possible harbinger for poor clinical o
133 ciency, central diabetes insipidus, and male hypogonadism as new features of PCSK1 insufficiency.
134 ined reversal of idiopathic hypogonadotropic hypogonadism as the presence of normal adult testosteron
135 palatal abnormalities, ventriculomegaly, and hypogonadism as well as additional findings such as bone
136 e randomly assigned 1199 men with primary or hypogonadism-associated osteoporosis who were 50 to 85 y
137 , placebo-controlled trial included men with hypogonadism at 316 US sites enrolled between May 2018 a
140 of 12,779 men who were newly diagnosed with hypogonadism between January 1, 1995, and August 31, 201
141 ted PRL may not only improve infertility and hypogonadism but also have a positive effect on the meta
143 population of middle-aged and older men with hypogonadism, carefully evaluated to exclude those at hi
145 (NKB) and its receptor show hypogonadotropic hypogonadism characterised by failure to progress throug
146 ptor, NK3 (NK3R), result in hypogonadotropic hypogonadism, characterized by an absence of pubertal de
148 s (n = 337) with congenital hypogonadotropic hypogonadism (CHH) showed enrichment of rare variants in
149 ns, resulting in congenital hypogonadotropic hypogonadism (CHH), a heterogeneous disease characterize
150 thus raising the hypothesis that ADT-induced hypogonadism could potentially lead to acute kidney inju
151 eficient in PC1 display hyperphagic obesity, hypogonadism, decreased GH, and hypoinsulinemic diabetes
152 mple, patients exhibit obesity, polydactyly, hypogonadism, developmental delay and skeletal abnormali
156 nactivation of Kiss1 causes hypogonadotropic hypogonadism, Donato et al., in this issue of the JCI, a
158 rogeneous and manifests as hypergonadotropic hypogonadism either as part of a syndrome or in isolatio
159 ale fertility are multifactorial and include hypogonadism, erectile dysfunction, sperm abnormalities,
161 ation (GnRHR E(90)K) causes hypogonadotropic hypogonadism (failed puberty associated with low or apul
162 n a patient with ataxia and hypogonadotropic hypogonadism, followed by targeted sequencing of candida
164 sm, central hypothyroidism, hypogonadotropic hypogonadism, growth hormone deficiency, or arginine vas
165 la, malignant hyperthermia, hypogonadotropic hypogonadism, growth retardation, hypoglycemia, myopathy
166 eterogeneous, frequently have not adhered to hypogonadism guidelines, and suffer from many intrinsic
167 sufficiency and associated hypogonadotrophic hypogonadism had a measurable response to gonadotropin-r
168 After multivariable adjustment, men with hypogonadism had higher odds than men with eugonadism of
169 iency, men with adult-onset hypogonadotropic hypogonadism had larger mean (+/-SD) testicular volumes
170 or pituitary hypoplasia and hypogonadotropic hypogonadism, has been reported in patients carrying SOX
174 ilar to patients with AS, including obesity, hypogonadism, hyperinsulinemia, retinal dysfunction and
176 ormal glucose homeostasis, hypogonadotrophic hypogonadism, hypocortisolism and elevated plasma proins
177 nally observed include acanthosis nigricans, hypogonadism, hypothyroidism, alopecia, short stature an
178 rweight or obesity, bone mineral deficiency, hypogonadism, hypothyroidism, and adrenal insufficiency,
180 er consisting of idiopathic hypogonadotropic hypogonadism (IHH) and anosmia, and is most commonly due
181 e the phenotype of isolated hypogonadotropic hypogonadism (IHH) associated with variants of these gen
188 associated with idiopathic hypogonadotropic hypogonadism in 55 women with hypothalamic amenorrhea an
189 and could be used to treat men with primary hypogonadism in a more specific and personalized approac
190 hypogonadal state were simulated by inducing hypogonadism in euthymic women-eight with and eight with
192 t to describe the effects on mood of induced hypogonadism in healthy young men, suggest that short-te
193 osomal recessive idiopathic hypogonadotropic hypogonadism in humans and mice, suggesting that this re
197 r adrenal insufficiency and hypogonadotropic hypogonadism in males affected by adrenal hypoplasia con
200 recognition of adult-onset hypogonadotropic hypogonadism in men as a distinct disorder expands the s
201 lated testosterone deficiency and late-onset hypogonadism in men remains a controversial concept.
202 short-term treatment of symptoms of clinical hypogonadism in men with symptomatic human immunodeficie
203 l testosterone, free testosterone, SHBG, and hypogonadism in men within the Million Veteran Program (
205 , and acute treatment substantially corrects hypogonadism in mice starved for 2 d without affecting b
207 ation for the occurrence of hypogonadotropic hypogonadism in patients with inactivating mutations in
209 ce-based criteria for identifying late-onset hypogonadism in the general population on the basis of a
210 tients had hypothyroidism, hypergonadotropic hypogonadism (in men), pulmonary insufficiency, swallowi
211 ry, and swallowing function; muscle atrophy; hypogonadism (in men); retinopathy; vascular and cerebra
212 vere obesity, mild learning difficulties and hypogonadism, in whom diagnostic tests for Prader-Willi
215 including kyphosis, uncoordinated movement, hypogonadism, infertility, severe skeletal muscle wastin
216 st neonatal hypotonia, feeding difficulties, hypogonadism, intellectual disability and sleep apnea.
226 n healthy young men, suggest that short-term hypogonadism is sufficient to precipitate depressive sym
230 of hospitalization differs between men with hypogonadism, men with eugonadism, and those receiving t
231 nia, childhood obesity, dysmorphic features, hypogonadism, mental retardation, and behavioral problem
232 oly/syn/brachydactyly, retinal degeneration, hypogonadism, mental retardation, obesity, diabetes, and
233 Testosterone therapy for congenital forms of hypogonadism must be lifelong, whereas testosterone trea
236 nd whether specific symptoms associated with hypogonadism (nighttime hot flushes and disturbed sleep)
237 her as normosmic idiopathic hypogonadotropic hypogonadism (nIHH) or with anosmia [Kallmann syndrome (
238 for osteoporotic fracture, the influence of hypogonadism on bone mineral density remains unclear, as
239 ngly, we determined prevalence and impact of hypogonadism on health-related quality of life in men wi
240 larly if high index of clinical suspicion of hypogonadism or hypoadrenalism) and evaluation of bone h
241 on (OR, 1.70, 95% CI, 1.19-2.44; AF, 11.5%), hypogonadism (OR, 3.27, 95% CI, 2.35-4.55; AF, 25.1%), g
242 m may arise from testicular disease (primary hypogonadism) or dysfunction of the hypothalamic-pituita
243 myelination, Hypodontia and Hypogonadotropic Hypogonadism) or RNA polymerase III (POLR3)-related leuk
244 , including kyphosis, severe muscle wasting, hypogonadism, osteopenia, emphysema, uncoordinated movem
245 tion in TACR3 for idiopathic hypogonatrophic hypogonadism (p.W275X) is associated with 1.25-year-late
246 erone levels were significantly lower during hypogonadism (P=.002, .04, and .046, respectively), but
250 ogen receptors; and (2) such alcohol-induced hypogonadism precedes changes in hepatic sex hormone hom
252 scular calcification, severe muscle wasting, hypogonadism, pulmonary emphysema, distention of intesti
255 ce, a syndrome emerged with delayed puberty, hypogonadism, relative macrocephaly, moderate short stat
257 whereas testosterone treatment of late-onset hypogonadism remains a matter of debate because of uncle
258 by retinal dystrophy, polydactyly, obesity, hypogonadism, renal abnormalities, and mental retardatio
259 besity, pigmentary retinopathy, polydactyly, hypogonadism, renal and cardiac abnormalities, and cogni
260 y, hepatic dysfunction, hypothyroidism, male hypogonadism, short stature and mild to moderate develop
261 deficient mice had isolated hypogonadotropic hypogonadism (small testes in male mice and a delay in v
262 ing, is characterized by neonatal hypotonia, hypogonadism, small hands and feet, hyperphagia and obes
264 stablished medical conditions known to cause hypogonadism, testosterone therapy may provide small imp
268 re a novel genetic model of hypogonadotropic hypogonadism that establishes essential role(s) of SF1 i
270 development and congenital hypogonadotropic hypogonadism, the European Union has funded a number of
272 adult onset of obesity and hypogonadotropic hypogonadism to study effects of gonadotropin releasing
274 ssors and the development of obesity-induced hypogonadism, underscoring the physiological and patholo
275 -producing cells that could be used to treat hypogonadism via transplantation and reestablishment of
276 unadjusted hazard ratio for depression with hypogonadism was 3.5 (95% confidence interval, 1.3-9.4)
280 ted proband with idiopathic hypogonadotropic hypogonadism was determined to have two separate mutatio
283 plasia congenita (AHC) with hypogonadotropic hypogonadism was recently shown to be caused by mutation
286 whom reversal of idiopathic hypogonadotropic hypogonadism was sustained after discontinuation of horm
290 tal development (idiopathic hypogonadotropic hypogonadism) was examined for mutations in a candidate
291 treatment in middle-aged and older men with hypogonadism, we examined the risk of clinical fracture
295 to testosterone) and symptoms suggestive of hypogonadism who were enrolled in the Testosterone Trial
297 sing hormone (GnRH) that is characterized by hypogonadism with delayed or absent puberty and dysfunct
300 ed with improved IIEF score in patients with hypogonadism (WMD, 1.61; 95% CI, 0.99-2.23; I2 = 0%), mo