ライフサイエンスコーパス: hypoinsulinemia

1 diabetes with insulitis, hyperglycemia, and hypoinsulinemia.

2 g, deficits in DAT function that result from hypoinsulinemia.

3 eks, mice on HFD exhibited hyperglycemia and hypoinsulinemia.

4 tal diabetes, evidenced by hyperglycemia and hypoinsulinemia.

5 demia, hepatic steatosis, hyperglycemia, and hypoinsulinemia.

6 alformations, impaired glucose tolerance and hypoinsulinemia.

7 ult mouse beta-cell caused hyperglycemia and hypoinsulinemia.

8 In HNF1A mutation carriers, we observed: 1) hypoinsulinemia, 2) insulinotropic effects of both GIP a

9 topic p53 gene encoding Delta40p53 developed hypoinsulinemia and glucose intolerance by 3 months of a

10 1 (S6K1), an mTOR target, in mice results in hypoinsulinemia and glucose intolerance.

11 glycemia and glucose intolerance with severe hypoinsulinemia and reduced islet insulin content and gl

12 body weight, caused fetal hyperglycemia and hypoinsulinemia, and decreased the relative islet area.

13 e glucose control due to insulin resistance, hypoinsulinemia, and deteriorating pancreatic beta-cell

14 eonates presented with severe hyperglycemia, hypoinsulinemia, and drastically reduced hormone express

15 GT) mice was associated with beta cell loss, hypoinsulinemia, and glucose intolerance.

16 -) mice exhibited diminished beta cell mass, hypoinsulinemia, and glucose intolerance.

17 cts, but have hypoplastic pancreatic islets, hypoinsulinemia, and impaired glucose tolerance.

18 Animals develop severe hyperglycemia, hypoinsulinemia, and ketoacidosis within 2 days and typi

19 e literature on the effect of hyperglycemia, hypoinsulinemia, and ketoacidosis, as well as the role o

20 l fat deposition, and induced hyperglycemia, hypoinsulinemia, and low-density lipoprotein hypercholes

21 ad reduced beta-cell proliferation and mass, hypoinsulinemia, and mild diabetes, phenotypes rescued b

22 isplayed higher blood glucose levels, marked hypoinsulinemia, and reduced beta-cell mass compared wit

23 rotocol IV; euglycemic (approximately 5 mM) -hypoinsulinemia (approximately 40 pM).

24 ocol I, hyperglycemic (approximately 10 mM) -hypoinsulinemia (approximately 40 pM); protocol II, eugl

25 breakdown, an acute gluconeogenic effect of hypoinsulinemia becomes manifest, whereas inhibition of

26 he severe hyperglycemia, diabetes incidence, hypoinsulinemia, beta-cell death, and loss of beta-cell

27 ssue, hypoadiponectinemia, hypoglycemia, and hypoinsulinemia but with relatively normal glucose dispo

28 Px resulted in stable hyperglycemia, hypoinsulinemia, decreased C-peptide, and increased glyc

29 pha deletion, mice develop hyperglycemia and hypoinsulinemia, due to defective beta cell function tha

30 stricted feeding (RF), immediately creates a hypoinsulinemia during the active phase, which initiates

31 eome of 120-d-old OVE26 transgenic mice with hypoinsulinemia, hyperglycemia, hyperlipidemia, and prot

32 lpha(-/-) mice, the p85beta(-/-) mice showed hypoinsulinemia, hypoglycemia, and improved insulin sens

33 We show that Asna1(beta-/-) mice develop hypoinsulinemia, impaired insulin secretion, and glucose

34 tion of streptozotocin (STZ), which produces hypoinsulinemia in rats.

35 These effects are in part due to hypoinsulinemia in T1DM mice, since insulin treatment, b

36 ts demonstrate that hyperglucagonemia during hypoinsulinemia increases net muscle protein catabolism

37 n both the streptozotocin (STZ) model, where hypoinsulinemia is chemically induced, and in the Ins2Ak

38 Moreover, hypoinsulinemia leads to an increase in glycogen synthas

39 ensitivity of a brain reward system and that hypoinsulinemia may be the common factor in food restric

40 of a euglycemic clamp study, indicating that hypoinsulinemia promotes insulin sensitivity in chronica

41 in-induced hyperglycemia, which results from hypoinsulinemia, reduced expression of renal insulin rec

42 -AL, ALS/Lt mice exhibited hyperglycemia and hypoinsulinemia, whereas ALR/Lt mice maintained normal p