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1  (cleft palate, cleft lip, anal atresia, and hypospadias).
2 be the best approach for midshaft and distal hypospadias.
3 m a completely female appearance to isolated hypospadias.
4 hat included vaginal and uterine defects and hypospadias.
5  anomalies, especially cryptorchidism and/or hypospadias.
6  co-occurring CHD compared with boys without hypospadias.
7  Leydig cell hypoplasia, cryptorchidism, and hypospadias.
8  higher prevalence of CHDs than boys without hypospadias.
9 al CHD screening programs for boys born with hypospadias.
10 rmation and potential implications for human hypospadias.
11 cellent outcomes for distal but not proximal hypospadias.
12 ween placental weight and cryptorchidism and hypospadias.
13 re older (p = 0.048) compared with boys with hypospadias.
14 , all of which have been implicated in human hypospadias.
15 ght into possible genetic mechanisms causing hypospadias.
16 such as cryptorchidism, urethral defects and hypospadias.
17 e-scale analysis of phytoestrogen intake and hypospadias.
18 sures to estrogenic compounds impact risk of hypospadias.
19 lies cryptorchidism (undescended testis) and hypospadias.
20 st relevant tissue sample available to study hypospadias.
21 yndrome disorders, namely cryptorchidism and hypospadias.
22 tween chlordane levels and cryptorchidism or hypospadias.
23 ion during the external genital phase causes hypospadias.
24 rgets the developing penis in utero to cause hypospadias.
25 tract, including digit loss, syndactyly, and hypospadias.
26 wth factor receptor 2 (Fgfr2) exhibit severe hypospadias.
27  (1.9%), breast mass (1.2%), club foot (1%), hypospadias (0.6%), hydrocephalus (0.6%), cleft lip or p
28 eo-oesophageal anomalies (2.25 [0.96-5.26]), hypospadias (1.96 [0.98-3.92]), and gastroschisis (3.19
29 ), injuries or wounds (54.7% and 98.9%), and hypospadias (50% and 100%).
30 s associated with loss of Hoxa13 function is hypospadia, a condition defined by the poor growth and c
31                                              Hypospadias, a developmental defect of the penis, is one
32 o compare AGD in boys with cryptorchidism or hypospadias against normative data.
33                           The odds ratio for hypospadias (among all mothers) was 0.8 (95% CI: 0.7, 1.
34 ng follow-up, 1,713 boys were diagnosed with hypospadias and 6,878 with cryptorchidism (3,624 underwe
35 nancies in Texas and Arkansas, 1485 boys had hypospadias and a co-occurring CHD.
36 s loss of ectodermal Fgfr2 results in severe hypospadias and absence of the ventral prepuce.
37   Ablation of Nr5a1(+) cells leads to severe hypospadias and alters cell differentiation in the penis
38 ow window of prenatal development results in hypospadias and chordee, whereas earlier disruptions cau
39 henotyping was performed in adolescents with hypospadias and controls.
40 g window did blocking androgen action induce hypospadias and cryptorchidism and altered penile length
41               Despite the high prevalence of hypospadias and cryptorchidism, the genetic basis for th
42 al testis, causing TDS-consistent effects of hypospadias and cryptorchidism.
43 sduce develop with variably penetrant severe hypospadias and incomplete midline fusion of the primiti
44 types: endodermal Fgfr2 deletion causes mild hypospadias and inhibits maturation of a complex urethra
45 dation, microcephaly, digital abnormalities, hypospadias and loose connective tissue) and resemble on
46 s in select reproductive organs (e.g. penile hypospadias and prostate dysgenesis but normal testis),
47      Ventral penile curvature occurs in both hypospadias and so-called 'chordee without hypospadias',
48 developmental link between Hoxa13-associated hypospadias and those produced by antagonists to androge
49 h hypospadias and so-called 'chordee without hypospadias', and so its correction is a topic of releva
50          Incomplete urethral tubularization (hypospadias) and anorectal abnormalities are two common
51  crypt-orchidism, 1.2 (95% CI: 0.6, 2.4) for hypospadias, and 1.9 (95% CI: 0.9, 4.0) for polythelia.
52  217 sons with cryptorchidism, 197 sons with hypospadias, and 557 sons with neither condition.
53 7,20-lyase deficiency, including micropenis, hypospadias, and gynecomastia, who is homozygous for CYP
54 irth, the 46,XY proband had a bifid scrotum, hypospadias, and micropenis consistent with clinical sta
55 ispose to the development of cryptorchidism, hypospadias, and WTs.
56 he male genital anomalies cryptorchidism and hypospadias are prematurity and low birth weight.
57 ale urogenital anomalies--cryptorchidism and hypospadias--are poorly understood.
58 ascular injury in hypogonadism, and identify hypospadias as a cardiovascular risk factor in males.
59                                        Using hypospadias as a surrogate of hypogonadism, we investiga
60  ratio, 2.7; 95% CI, 1.4-5.3), and boys with hypospadias born to Hispanic mothers in Texas were 1.5 t
61 ly to have a co-occurring CHD than boys with hypospadias born to non-Hispanic White mothers.
62 sm were longer than mean values in boys with hypospadias (both p < 0.01) and shorter than mean values
63 al defect characterized by hypertelorism and hypospadias, but additional midline malformations are al
64  developmental factors in the development of hypospadias, but there is doubt whether the incidence of
65 e analysis included data on mothers of 1,250 hypospadias cases and 3,118 controls who delivered their
66 association study on 1,006 surgery-confirmed hypospadias cases and 5,486 controls from Denmark.
67 s 15.7% lower beta-value at cg14436889 among hypospadias cases than controls (EWAS P = 5.4e-7) and is
68 thers of 593 gastroschisis cases, 1,142 male hypospadias cases, and 4,399 nonmalformed controls.
69 tissue we identified 25 CpGs associated with hypospadias characteristics and used one-sample two stag
70               Reports of CPAs, which include hypospadias, chordee, micropenis, and ambiguous genitali
71 ed with many common birth defects, including hypospadias, cleft lip with or without cleft palate, or
72  twins and by patterns of cryptorchidism and hypospadias co-occurrence in individuals.
73 s identified as a candidate gene involved in hypospadias, cryptorchidism and other genitourinary (GU)
74  to differences of sex development including hypospadias, cryptorchidism, and infertility.
75  reproductive tract abnormalities (including hypospadias, cryptorchidism, hypospermatogenesis, and te
76                      Arteries from boys with hypospadias demonstrated increased U46619-induced vasoco
77 en external urogenital and anorectal tracts; hypospadias - ectopic ventral positioning of the urethra
78  of a small utricle (not in the patient with hypospadias), ejaculatory duct reflux, internal urachal
79 the British Pediatric Association coding for hypospadias (exposure) and major CHDs (primary outcomes)
80 rgical techniques for treating patients with hypospadias, exstrophy, incontinence, and ambiguous or v
81              In this cohort study, boys with hypospadias had a higher prevalence of CHDs than boys wi
82                                    Boys with hypospadias had shorter mean AGD and penile length SDS t
83 iation between placental weight at birth and hypospadias has been indicated.
84 52, 95% confidence interval: 1.31, 1.76) and hypospadias (hazard ratio = 1.97, 95% confidence interva
85 deletion of Fgfr2 results in the most severe hypospadias highlights a major role for Fgfr2 in the dev
86 mass, obstetric fistula, undescended testes, hypospadias, hydrocephalus, cleft lip or palate, and clu
87 ses, obstetric fistulas, undescended testes, hypospadias, hydrocephalus, cleft lip/palate, and clubfo
88                  We examined whether risk of hypospadias (i.e., a congenital malformation in which th
89  5.503% (95% CI, 5.495%-5.511%) of boys with hypospadias in Arkansas have a co-occurring CHD.
90 beta-catenin knockout animals develop severe hypospadias in both sexes raises the possibility that th
91 ental and molecular mechanisms that underlie hypospadias in Fkbp52-deficient mice.
92  Fgfr2 or its ligand Fgf10 results in severe hypospadias in mice, in which the entire urethral plate
93 nor abnormalities at or shortly after birth (hypospadias in one baby and rotation of small intestine
94  7.024% (95% CI, 7.020%-7.028%) of boys with hypospadias in Texas and 5.503% (95% CI, 5.495%-5.511%)
95 ospadias repair, especially that of proximal hypospadias (in which reconstruction of a long urethra i
96 nile length SDS decreased as the severity of hypospadias increased (ptrend = 0.078).
97  patient presented with developmental delay, hypospadias, inguinal hernia and dysmorphic features whi
98 cele [adult and paediatric]), hydrocephalus, hypospadias, injuries or wounds, neck mass, undescended
99                                              Hypospadias is a common birth defect in humans, yet its
100                                              Hypospadias is a common birth defect of the male urinary
101                                              Hypospadias is a common birth defect where the urethral
102                                              Hypospadias is a common congenital condition in boys in
103                                              Hypospadias is a congenital defect of the external genit
104                                              Hypospadias is a congenital malformation resulting from
105                                              Hypospadias is a urethral tube defect defined by misloca
106                                              Hypospadias is associated with vascular dysfunction and
107 ate of hypogonadism, we investigated whether hypospadias is associated with vascular dysfunction and
108  but there is doubt whether the incidence of hypospadias is increasing or not.
109 of FK506-binding protein-52 (Fkbp52) develop hypospadias, most likely due to actions of Fkbp52 as a m
110 d adjusted odds of cryptorchidism (n = 219), hypospadias (n = 199), and polythelia (extra nipples) (n
111 chidism (n = 71, age 13.4 +/- 5.8 months) or hypospadias (n = 81, age 11.4 +/- 6.2 months) were recru
112                  In Hoxa13(GFP)-mutant mice, hypospadias occur as a result of the combined loss of Fg
113  every specific CHD analyzed among boys with hypospadias, occurred outside of chromosomal anomalies,
114                 Other abnormalities included hypospadias, opacification of a small utricle (not in th
115  and penile length were reduced in boys with hypospadias or cryptorchidism relative to normative data
116 rders of fetal masculinization, resulting in hypospadias or cryptorchidism, are common, but their cau
117 nce, is susceptible to birth defects such as hypospadias or incomplete closure of urethra along the p
118 ychlordane level in either cryptorchidism or hypospadias (p-trend all > 0.45).
119                                       Severe hypospadias, particularly that associated with significa
120 expression in the urethra, and an associated hypospadias phenotype, suggesting that these genes are d
121 loss of estrogen signaling results in a mild hypospadias phenotype, the most common manifestation of
122  The use of engineered tissue substitutes in hypospadias reconstruction has also been applied clinica
123 e risk for co-occurring CHDs among boys with hypospadias remains unknown, which limits screening and
124 teries from penile skin from boys undergoing hypospadias repair and controls were isolated and functi
125 as challenged more traditional approaches to hypospadias repair and is now considered by many pediatr
126                    Many technical aspects of hypospadias repair and variations of perioperative manag
127  of penile degloving procedures, phimosis or hypospadias repair, and penile cancer resection.
128                                              Hypospadias repair, especially that of proximal hypospad
129   After more than 100 years of innovation in hypospadias repair, new concepts regarding penile curvat
130 otentially be preserved in both phimosis and hypospadias repair.
131                                 In addition, hypospadias severity and maternal race and ethnicity wer
132  quartile-specific ORs for cryptorchidism or hypospadias show no notable associations with trans-nona
133                                              Hypospadias surgery has been in continuous evolution for
134                     Continuing innovation in hypospadias surgery offers additional options for straig
135                       Further development of hypospadias surgery would benefit from objective, standa
136 le to simplify decision-making algorithms in hypospadias surgery, while achieving good functional and
137                          In adolescents with hypospadias, systolic blood pressure (P = 0.005), pulse
138         The relationship seemed stronger for hypospadias than for cryptorchidism.
139 pendently associated with the likelihood for hypospadias to co-occur with a CHD; boys in Texas with t
140  exhibit genital anomalies, which range from hypospadias to complete male-to-female sex reversal.
141 3.4) more likely than boys with first-degree hypospadias to have a co-occurring CHD, with consistent
142 cial support with risks of gastroschisis and hypospadias, using data from the National Birth Defects
143 in the bladder wall; affected males may have hypospadias (ventrally misplaced urethral opening) of va
144  episode data compared men with a history of hypospadias vs. controls.
145 in Texas with third-degree (ie, more severe) hypospadias were 2.7 times (95% CI, 2.2-3.4) more likely
146                                    Boys with hypospadias were 5.8 times (95% CI, 5.5-6.1) more likely
147 ongenital heart defects, inguinal hernia, or hypospadias were also reported.
148                           Cryptorchidism and hypospadias were associated with low weight-for-gestatio
149                                Men born with hypospadias were at increased risk of arrhythmia [odds r
150 AGD in human infants with cryptorchidism and hypospadias, which are potential manifestations of TDS d
151  surgical techniques have been developed for hypospadias, with excellent outcomes for distal but not

 
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