ライフサイエンスコーパス: hypotheses

1 pangenome software or comparing evolutionary hypotheses.

2 predictions from their embedded mechanistic hypotheses.

3 ts that can adjudicate amongst the different hypotheses.

4 tools for testing biological and therapeutic hypotheses.

5 ign approaches to test clinically meaningful hypotheses.

6 als unexpected findings that reject previous hypotheses.

7 sed over a century ago and generate many new hypotheses.

8 es to generate new therapeutic and biomarker hypotheses.

9 SC-based virotherapy as well as generate new hypotheses.

10 of research tools and a wide range of novel hypotheses.

11 has focused research efforts and driven new hypotheses.

12 and Rca is critical to formulate mechanistic hypotheses.

13 etic framework are beholden to specific tree hypotheses.

14 an biological samples to generate actionable hypotheses.

15 novel biological insights and generating new hypotheses.

16 approaches to formally test epidemiological hypotheses.

17 eration of impactful biological insights and hypotheses.

18 in amorphous films, to investigate these two hypotheses.

19 h to account for testing multiple correlated hypotheses.

20 amental mechanisms and to formulate and test hypotheses.

21 ovide an excellent opportunity to test these hypotheses.

22 sis required to test biologically meaningful hypotheses.

23 The POETIC trial aimed to test these two hypotheses.

24 rent study aimed to dissociate between these hypotheses.

25 Our data falsify these hypotheses.

26 Here, we tested two main hypotheses.

27 us has been reached regarding these opposing hypotheses.

28 n the two historically competing wing origin hypotheses.

29 mutational scan data can inform evolutionary hypotheses.

30 or power to differentiate competing spatial hypotheses.

31 ADHD-associated alleles compared to previous hypotheses.

32 erating, validating, and testing mechanistic hypotheses.

33 to keep track of the facts, predictions, and hypotheses?

34 the same dataset, testing the same 9 ex-ante hypotheses(1).

35 Here, we tested two hypotheses: (1) memory-guided predictions about CCD prec

36 Accordingly, we sought to address two hypotheses: (1) passive hyperthermia will increase the c

37 concordance among coders about the number of hypotheses (14%), indicating that they are often not cle

38 at, in keeping with certain quantum physical hypotheses, a weak 7 MHz radiofrequency magnetic field s

39 nimals to be useful for testing evolutionary hypotheses about cognition, researchers must provide evi

40 created synthetic datasets based on existing hypotheses about combinatorial transcription factor bind

41 relevant population for testing evolutionary hypotheses about emotion.

42 key studies testing intrinsic and extrinsic hypotheses about geographic range size under contrasting

43 t of abstract object categorization to guide hypotheses about how infants might learn abstract emotio

44 75oS with 11 environmental variables to test hypotheses about how macroecological patterns in flower

45 Here we review recently developed hypotheses about how SARS-CoV-2 might alter the cells an

46 The first hypotheses about how the immune system affects cancers w

47 a description of the system and identifying hypotheses about how the system may change in response t

48 Many verbally described hypotheses about language lateralization and recovery ha

49 This Review proposes that existing hypotheses about language recovery after stroke can be c

50 is a powerful engine for generating testable hypotheses about mechanistic explanations of brain funct

51 chers, providing a rigorous platform to test hypotheses about regulation of mitotic exit.

52 and alpha training could be used for testing hypotheses about synchrony.

53 we compared three psychologically plausible hypotheses about the algorithmic implementation of imita

54 pha-beta pairs, we tested five non-exclusive hypotheses about the causes of variation in multiple mat

55 Hypotheses about the cultural and demographic impacts of

56 e initial iridophore stripe, and to generate hypotheses about the functions of leopard.

57 her, and then used path analyses to generate hypotheses about the mechanistic connections between imm

58 Furthermore, PSCAN enables generation of hypotheses about the molecular basis for the association

59 These results provide testable hypotheses about the organization of hand control in M1.

60 Hypotheses about the origin of eukaryotic cells are clas

61 cage experiments in ponds to test competing hypotheses about the role of abiotic and biotic mechanis

62 Here we offer a set of causal hypotheses about the role of personality, integrating ps

63 Thus, to fully address the hypotheses about the role of social associations it is i

64 studies have been performed, generating many hypotheses about the roles of particular genes and molec

65 ed integrative, comparative approach to test hypotheses about the scope and strength of convergence i

66 lates for color appearance and generates new hypotheses about the structure of color space.

67 ow factual evaluation of previously untested hypotheses about the timing, geographic pattern, and cul

68 veniles) in forest and coffee, and generated hypotheses about their role in species persistence.

69 We resolve a controversy over two competing hypotheses about why people object to randomized experim

70 Two mutually exclusive hypotheses account for the evolution of terminal rooting

71 that stimulate animal metamorphosis and test hypotheses addressing their mechanisms of action.

72 Previous relationship hypotheses among subfamilies are strongly corroborated,

73 ISE framework to spur the development of new hypotheses, analytical tools, and model structures acros

74 We then define key hypotheses and areas for future research that can use th

75 Here we review historical hypotheses and discuss the present understanding of how

76 stiffness mapping enables the generation of hypotheses and potentially the rigorous testing of mecha

77 echanisms, for the purpose of generating new hypotheses and predicting new experiments designed to he

78 Our results challenge previous hypotheses and provide an alternative, although compleme

79 species with distinct fruit types will test hypotheses and provide insights into mechanisms of flesh

80 he deep cortical layers represent perceptual hypotheses and thereby shed light on the computational a

81 The results also include testable hypotheses and tools for understanding and managing the

82 To test these hypotheses and uncover additional functions of wrapping,

83 has the potential to provide novel theories, hypotheses, and interpretations that can inform idealize

84 the identification and testing of competing hypotheses, and the current limitations of observational

85 Paleobiogeographic and divergence time hypotheses are contingent on the accurate systematic pla

86 We propose that these hypotheses are correct when using techniques that simult

87 Most existing hypotheses are descriptive and lack a clear mechanistic

88 define bounds for the notion that perceptual hypotheses are direct derivatives of experience and are

89 Several hypotheses are explored to discuss the unique delta(44/4

90 However, pterosaur dietary hypotheses are poorly constrained as most rely on morpho

91 These hypotheses are tested in a longitudinal study of schizop

92 Current hypotheses are that dopamine influences motor control by

93 These two mutually incompatible hypotheses are thus both incorrect.

94 drugs, without requiring a priori molecular hypotheses, are critically needed.

95 ral principles of regeneration and elaborate hypotheses as to why this mammal is successful at regene

96 l of DeepWAS to generate testable functional hypotheses based on genotype data alone.

97 Here we tested if hypotheses based on life history and the leaf economics

98 Two major mechanism hypotheses, both involving ESAA relief, were explored th

99 We tested our hypotheses by employing a DEM-based, depth-censoring app

100 d radiations, and therefore counter previous hypotheses by showing that tighter cranial integration,

101 This study tested both hypotheses by subjecting raw, marinated and microwave-co

102 We contrasted these hypotheses by testing inexperienced hatchlings of five s

103 Both hypotheses claim the same qualitative mechanism-properly

104 These hypotheses clarify the causal and constitutive relations

105 m upon which it is possible to establish new hypotheses, clear predictions, and quantifiable expectat

106 ctural equation models, to generate and test hypotheses concerning environmental moderation of stocki

107 l behaviour within this taxon, and clarifies hypotheses concerning hominin phylogeny.

108 Second, we construct hypotheses concerning the correlations between the world

109 ms for conserved cellular functions and test hypotheses concerning the generation of molecular divers

110 ity of the LTMI as a resource for generating hypotheses concerning tumor-microenvironment interaction

111 Both hypotheses consider variable relative humidity, but neit

112 -on new empirical research to test competing hypotheses [D.

113 ssors are often inconsistent with predefined hypotheses derived from current trait-based thinking, pa

114 Following hypotheses derived from prior research into neuropsychia

115 ecies and human cultures we test a series of hypotheses derived from this theory and find support for

116 seemingly arbitrary, choices in formulating hypotheses, designing protocols, collecting data, analyz

117 ayesian model comparison of various a priori hypotheses differing in how low-risk healthy, high-risk

118 1 mobility issues in the survey confirms our hypotheses, elucidating the cultural cognition or ration

119 Results provide testable hypotheses explaining both intermittent and regular patt

120 We tested whether these macroecological hypotheses explaining cuticle lightness held at habitat

121 he tolerance and climatic niche conservatism hypotheses for climate-diversity relationships, and sugg

122 latitude, Kaspari et al. (2020) tested three hypotheses for explaining sources of sodium (Na) limitat

123 g sources of sodium (Na) limitation and five hypotheses for explaining sources of sugar limitation of

124 and climate change, and can provide testable hypotheses for extant species expected to experience sub

125 f these patterns, suggesting new mechanistic hypotheses for further investigation.

126 ating gene expression and generates testable hypotheses for future functional analyses.

127 In this Review, we explore proven and novel hypotheses for how modifiable risk factors and environme

128 Towards a remedy, we present a suite of hypotheses for how sodium and sugary exudate availabilit

129 and lastly suggests some potential unifying hypotheses for its biological role.

130 racellular end of the pore supports existing hypotheses for mechanisms of ion selectivity.

131 t would be very useful to derive mechanistic hypotheses for newly discovered inhibitors.

132 We discuss three major mechanistic hypotheses for receptor activation: ligand-induced dimer

133 des a rapid approach for generating testable hypotheses for specific candidates identified by genome-

134 Informed by these models, we offer novel hypotheses for the enrichment of integrase and transposa

135 Atom level structural studies provide hypotheses for the improved affinity to this receptor su

136 ty framework; (c) develop thermal adaptation hypotheses for the MMRT framework; and (d) explore new q

137 We discuss possible hypotheses for the rapid recovery.

138 ions is critically examined, and alternative hypotheses for the stereodirecting effect of such esters

139 We discuss testable hypotheses for the ultimate (evolutionary) and proximate

140 Hypotheses for toxicological effects of cadmium (Cd), ar

141 erving as a model for generating and testing hypotheses from omics datasets, this study puts forth a

142 light the use of tuxnet to form new testable hypotheses from previously explored data.

143 mperature and pH on AOB and AOA into several hypotheses, generating predictions that were tested in s

144 cs, thus providing more confident biological hypotheses generation.

145 While a number of hypotheses have been developed to explain this phenomeno

146 Two simplifying hypotheses have been proposed for whole-plant respiratio

147 Multiple hypotheses have been proposed to explain the origins of

148 Two primary hypotheses have been proposed to explain these patterns.

149 Although many hypotheses have been proposed to explain these relations

150 Different hypotheses have been proposed to explain this enhancemen

151 Two opposing hypotheses have been proposed: liberalizing killing may

152 Three key hypotheses have been used to explain these macroecologic

153 Competing hypotheses have identified five separate migrations from

154 Hypotheses have linked range expansion and emergence of

155 ch marker, in which the null and alternative hypotheses have no common support.

156 These hypotheses have not been evaluated concurrently, and thi

157 gy propelled some of these shifts, but these hypotheses have not been tested with ancient DNA.

158 Two hypotheses have received empirical support: that a high

159 We present two conceptual hypotheses (homoeostatic sensitivity and dynamic sensiti

160 rolled manifold (UCM) hypothesis to test two hypotheses: (i) individual motor units are organized int

161 We tested these three hypotheses in 2 experiments (N = 24 and N = 44) featurin

162 We distinguish between these hypotheses in a simplified form of contour integration,

163 We tested these hypotheses in a socio-spatial context using individual c

164 predictions of the climate change and aging hypotheses in Abies alba, Fagus sylvatica, Larix decidua

165 n tissues, which will allow new insights and hypotheses in basic and translational research.

166 fic process of cyclically preregistering new hypotheses in between waves of data collection, we ident

167 intractable when used to test composite null hypotheses in irregular statistical models.

168 (ABMs) have been utilized to explore similar hypotheses in many areas of health research.

169 Most theories and hypotheses in psychology are verbal in nature, yet their

170 lexity and a means for testing developmental hypotheses in the broader context of mammalian evolution

171 r this increase remain unknown but plausible hypotheses include greater exposure to potential risk fa

172 However, all hypotheses lacked any integrative analysis of the site f

173 This refutes existing hypotheses linking sexual dimorphism, ontogeny and socia

174 of interrelated neuroscientific and clinical hypotheses, models, experiments, and predictions with wh

175 and demonstrates that Darwin's two opposing hypotheses need not be mutually exclusive.

176 In contrast to our hypotheses, no differences were detected in bottle-feedi

177 The trial was powered to test 3 hypotheses (noninferiority of cangrelor compared with ti

178 rthern Hemisphere challenges biogeographical hypotheses of a Gondwanan origin of crown birds(3), and

179 origin of this species, challenging earlier hypotheses of an Old-World origin.

180 ages to efficiently test early-developmental hypotheses of autism.

181 producing palynological identifications and hypotheses of biological affinity.

182 ross 54 grasslands, consistent with multiple hypotheses of bottom-up and top-down regulation.

183 pecies, allowing direct tests of comparative hypotheses of brain organization.

184 experimental tests remain inconsistent with hypotheses of canonical rhythmogenic cellular or synapti

185 The first scenario is consistent with hypotheses of enhanced nutrient loading during OAEs, whi

186 We test hypotheses of eruption triggering using 3-dimensional fi

187 answer this question, Medawar proposed three hypotheses of how a mother supports her fetus in utero,

188 s and the importance of considering multiple hypotheses of mesopredator population regulation.

189 antitative baseline to constrain model-based hypotheses of plant responses to eCO(2) under P limitati

190 Two major competing hypotheses of polish formation have been proposed: abras

191 eview, we discuss the earliest knowledge and hypotheses of the mechanisms of immune pathology in the

192 mates of binding affinities, and 4) testable hypotheses of the molecular mechanism underlying the pos

193 The fate of scientific hypotheses often relies on the ability of a computationa

194 arameters easily manipulated to develop/test hypotheses on a signal's origin.

195 gn of future investigations to test specific hypotheses on adventitial pathobiology.

196 Here we test macroevolutionary hypotheses on co-expression, co-regulation, and diversif

197 rofile on CFTR structures raises mechanistic hypotheses on drug action, suggesting that VX-770 might

198 inant proteins have generated transformative hypotheses on how mechanical forces are generated and se

199 ghts into these motors has led to structural hypotheses on how these motors fulfill their function.

200 However, testing these mechanical hypotheses on proteins in their natural environment rema

201 he ppH protocol detects EVs without a priori hypotheses on the dynamics of vesicle formation.

202 appendages" with a central role in competing hypotheses on the early evolution of the head [1-3, 6-8]

203 experimental evidence substantiates previous hypotheses on the effects of spiral artery remodelling i

204 e of force distribution and to test existing hypotheses on the evolution of turtle skull architecture

205 c-epidemiological model and contrasted three hypotheses on the influence of temperature on disease tr

206 al population allows for testing of specific hypotheses on the neural implementation of the dual-rout

207 sters in ProtCID, enabling the generation of hypotheses on the structures of biological assemblies of

208 new cholinergic connections leading to novel hypotheses on their functional significance.

209 One of the hypotheses on which the pseudophase model is based, is t

210 In agreement with our preregistered hypotheses, participants who were disadvantaged by unequ

211 Several hypotheses posit a link between the origin of Homo and c

212 icroglial activation, challenging prevailing hypotheses positing neuroimmune activation as central to

213 unctional and phylogenetic diversity as some hypotheses predict, and whether it is paralleled by clim

214 North American grasslands to test alternate hypotheses predicting 100-fold shifts in the biomass of

215 Hypotheses regarding body size in relation to urbanizati

216 ixed at the origin of the phylum, countering hypotheses regarding developmental processes governing t

217 s, while also providing a wealth of testable hypotheses regarding oncogenic mechanisms that may influ

218 ity of infectious agents between sites, test hypotheses regarding pathogen dispersal, and quantify pa

219 o increased acceptance of once controversial hypotheses regarding phylogenetic relationships, hybridi

220 atical transmission models to test different hypotheses regarding the degree of density dependence an

221 els, reporting B coefficients, to test study hypotheses regarding the effects of individual-level and

222 Many hypotheses regarding the evolution of social play have b

223 Thus, our results provide hypotheses regarding the functional role of olfactory ci

224 Based on our results, we propose hypotheses regarding the hypervariability of CTLs and co

225 approach allows comparisons of two competing hypotheses regarding the regulation of ENaC.

226 Long-standing hypotheses regarding the retromer sorting mechanism posi

227 tified in 3D to address previous qualitative hypotheses regarding the stance of Euparkeria.

228 l Proterozoic is a critical step for testing hypotheses related to extreme carbon isotope excursions

229 n-Ya-Wana Conservancy, South Africa, to test hypotheses related to spatial influences of predation ri

230 enomics offers innovative approaches to test hypotheses related to the source and timing of introduct

231 In this study, we tested hypotheses related to top-down, bottom-up and density-de

232 tructural information that allows testing of hypotheses relating form to function.

233 However, empirical studies addressing these hypotheses remain limited in scope and number.

234 Consistent with our hypotheses, results revealed a spatio-temporal pattern o

235 Counter to our hypotheses, results showed an increase in anxiety-potent

236 nstrate that concurrent support for multiple hypotheses should be the starting point for future FLS a

237 he perception of external sounds, leading to hypotheses such as "tinnitus filling in the temporal gap

238 ; we discuss key culture-gene coevolutionary hypotheses, such as those surrounding self-domestication

239 Current hypotheses suggest that flotillin proteins are required

240 onstructions reinforce specific transmission hypotheses suggested by the inclusion of travel history

241 We then discuss research and hypotheses surrounding the tissue mechanisms underlying

242 Overall, the results support the hypotheses that (1) transient indoor activities can give

243 ucted with these preparations to develop the hypotheses that 1) force production in myofibrils is lar

244 submit that it is compatible with a range of hypotheses that are difficult to differentiate empirical

245 al worlds are a robust mechanism for testing hypotheses that are impossible to study in the wild.

246 These structural constraints constitute hypotheses that can be tested experimentally.

247 ssil occurrences for conifers, we tested the hypotheses that clade competition or climate change led

248 er, current methods are insufficient to test hypotheses that concern physical properties deep in livi

249 ty of this tool compound to test therapeutic hypotheses that depend on mTOR hyperactivity in the CNS.

250 se models are founded on robust mathematical hypotheses that describe how A responds to changes in li

251 We frame our results in the context of two hypotheses that explain variation in trophic niche-the n

252 se our results to generate a set of testable hypotheses that explore the influence of urban change on

253 pose to repurpose this AI to test ecological hypotheses that have been intractable using traditional

254 Here, we tested the hypotheses that infection of cultured human gingival epi

255 l results to produce experimentally testable hypotheses that may aid experimental explorations of pat

256 We tested the hypotheses that NBResilience protects against MACE, and

257 as-phase process thus disputing conventional hypotheses that synthesis of polycyclic aromatic hydroca

258 Results corroborate hypotheses that the deep branch of the overturning circu

259 cells pooled from both sexes, we tested the hypotheses that the level of endogenous NQO1 activity li

260 We here tested the hypotheses that the post-synaptic protein Neuroligin-1 (

261 ame time, these findings are consistent with hypotheses that these same, reciprocal interactions unde

262 ndings led several investigators to test the hypotheses that treatment of anemia and ID in HF would i

263 Herein we tested the hypotheses that: i) systemic K(ATP) channel inhibition v

264 ree general frameworks (sets of premises and hypotheses) that, in our view, have so far dominated the

265 Here we show that, contrary to our initial hypotheses, the catalytic mechanism is monometallic and

266 argely consistent with previous phylogenetic hypotheses, the gene trees reveal high levels of genealo

267 In contrast with our hypotheses, there was no evidence that IE altered cognit

268 to preclinical observations and our a priori hypotheses, these exploratory results replicate those of

269 Contrary to initial hypotheses, they can also be active during action observ

270 ehavior of wild animals to test evolutionary hypotheses, this approach has only recently become popul

271 t, we can leverage logical connections among hypotheses to draw reliable conclusions that guide our r

272 Hypotheses to explain links between UA deposition and pr

273 ty, we constructed numerically substantiated hypotheses to explain the discriminatory role of a recen

274 FLSs may be adaptive, with several competing hypotheses to explain their function.

275 These results can be used to generate novel hypotheses to gain a greater understanding of p75NTR in

276 e methodological suggestions and theoretical hypotheses to guide future research.

277 xome sequencing on this cohort and applied 2 hypotheses to our variant filtering.

278 Existing hypotheses to solve this problem require restrictive ass

279 e a conceptual framework for formulating new hypotheses to study these interactions.

280 Five different hypotheses using a cross-sectional and a longitudinal de

281 the age and area and ecological opportunity hypotheses using metrics for both taxonomic and phylogen

282 To test these two contrasting hypotheses, we analyse the most plausible pathways in th

283 To reconcile these competing hypotheses, we examined different types of motor inhibit

284 Contrary to our hypotheses, we found no differences in performance betwe

285 To test these hypotheses, we quantified migratory status- (resident/mi

286 To test these hypotheses, we recorded neuronal activity in the orbitof

287 To test those hypotheses, we sampled single-unit activity from connect

288 To test these hypotheses, we studied learning with variable outcome-pr

289 Two hypotheses were tested for the genetic diversity of thes

290 Our three hypotheses were that TGC during the N-back task would be

291 The pre-specified study hypotheses were that that the prevalence of complicated

292 (iii) Formulated hypotheses were: first, in lieu of Pearson's correlation

293 of convergence for the null and alternative hypotheses, whereas commonly used local alternative mode

294 These hypotheses, which are congruent with the geological lite

295 These hypotheses, which will be further investigated in the ne

296 ultaneously evaluate thousands of correlated hypotheses, while adjusting for multiple testing, to scr

297 urate and interpretable results for specific hypotheses will be best obtained using small databases c

298 Here, we advance existing hypotheses with a new framework that accounts for quanti

299 is approach allowed us to test preregistered hypotheses with high ecological validity and statistical

300 We outline hypotheses within a quantitative framework, and analyse