ライフサイエンスコーパス: hypothesis

1 increased available energy (more individuals hypothesis).

2 against those expected under a suitable null hypothesis.

3 We refer to this formulation as the 3-level hypothesis.

4 tor experience, supporting the sensitization hypothesis.

5 data support the retinal equilibrium binding hypothesis.

6 ers and finds its roots in the old RNA world hypothesis.

7 ns, taken as support for the HCO3- metabolon hypothesis.

8 oung relative to older animals, negating our hypothesis.

9 vers, offers a tractable system to test this hypothesis.

10 ed, consistent with the direct deacetylation hypothesis.

11 f C-reactive protein (CRP), counter to their hypothesis.

12 This study is an empirical test of this hypothesis.

13 with natural ITD statistics, supporting our hypothesis.

14 self-similarity underlying the urban scaling hypothesis.

15 The plasticity-first hypothesis [2-4] proposes that natural selection can imp

16 To test this hypothesis, a glutamate selective microelectrode array (

17 From this redundancy reduction hypothesis, a theory of retinal color coding emerged in

18 The dual hit hypothesis about the pathogenesis of Parkinson disease (

19 A statistical model represents a hypothesis about the underlying biological process.

20 The amyloid cascade hypothesis, according to which the self-assembly of amyl

21 To test the hypothesis, allelic variants at the SD1-2, 7-1, 7-2, and

22 upport the long-standing incessant ovulation hypothesis and cortical inclusion cyst involvement in sp

23 to Anderson's conjecture without additional hypothesis and improves results of C.

24 A PRO hypothesis and relevant PRO domains were specified in 36

25 cells encode 3D space: the rotational plane hypothesis and the dual-axis model.

26 a rare glimpse into Anfinsen's thermodynamic hypothesis and the process of thermal denaturation, norm

27 To evaluate this hypothesis and unravel its details, we identified all ph

28 Consistent with this hypothesis, Arabidopsis badc1 badc3 mutant lines grown i

29 Other possible tests of the supernova hypothesis are discussed.

30 This Hypothesis article aims first to provide an accessible o

31 The Bayesian brain hypothesis, as formalized by the free-energy principle,

32 In this hypothesis, at the time of the origin of life there were

33 We re-evaluate the evidence for this hypothesis based on recent findings and discuss the mult

34 deline-compliant (core) studies and academic hypothesis-based studies to assess the effects of bisphe

35 nalized through the bent bond/antiperiplanar hypothesis (BBAH).

36 Here, we tested this hypothesis by coupling the reduction of GalA to the oxid

37 We tested "the expensive germ line" hypothesis by generating germline-free zebrafish Danio r

38 We tested that hypothesis by infecting an oviductal epithelial cell lin

39 We tested this hypothesis by measuring substantial macroscopic CDI, in

40 ulation of excitability and have tested this hypothesis by perturbing a signal transduction pathway t

41 We test this hypothesis by recording neural responses in the visual c

42 The results supported our hypothesis by showing increased inflammation and fibrosi

43 However, this hypothesis cannot explain the multi-Myr lag between the

44 By the technical-reasoning hypothesis, cognitively-impaired individuals will lack t

45 le logistic regression adjusted for the same hypothesised confounders.

46 Though controversial, the savanna hypothesis continues to motivate research into the palae

47 This hypothesis could lead to basic, translational, and clini

48 Estonia, which-according to the biodiversity hypothesis-could relate to differences in early microbia

49 The first hypothesis, decision biasing (DB), postulates that imita

50 have been identified employing conventional hypothesis-driven approaches as contributing to allergen

51 In a hypothesis-driven in vitro and in silico approach, we tu

52 Here we develop a hypothesis-driven resilience framework for urban transpo

53 A new Abeta-independent hypothesis emerges where the amyloidogenic processing of

54 ia, we investigate the effects of previously hypothesised environmental and virological drivers of in

55 ators described here add information to this hypothesis, expanding the knowledge on molecular relatio

56 Mission) blank-sky observations to test this hypothesis, finding no evidence of the 3.5-keV line emis

57 na, supporting the alternative stable states hypothesis for Africa, and this result is corroborated b

58 These results provide a testable hypothesis for future studies of more-complex natural co

59 A qualitative pharmacophore hypothesis for small molecule ligands at GPVI is also pr

60 A hypothesis for the evolutionary selection of ddl contain

61 biomes), and a new, large-scale phylogenetic hypothesis for the genera that occur in these ecosystems

62 A loss of GABA signaling is a prevailing hypothesis for the pathogenesis of schizophrenia.

63 A hypothesis-free profiling of ACE2 suggests tongue kerati

64 ure directions for mNGS technology and other hypothesis-free testing methodologies that are in develo

65 ontext, much consideration has been given to hypothesis-free, culture-independent tests that can be p

66 high-dimensional, we formulate a well-posed hypothesis from a Bayesian point of view and suggest a n

67 like exoplanets are observed, testing the HZ hypothesis from this relationship could be difficult.

68 Our web-based implementation is ideal for hypothesis generation and education in research and larg

69 options that are designed to assist in novel hypothesis generation, as well as data management, onlin

70 chemical toxicity assessment and mechanistic hypothesis generation, here we present an intuitive webt

71 Although this hypothesis has been repeatedly questioned, it has never

72 tion stabilizes dendritic branches, but this hypothesis has not been causally tested in vivo in the m

73 However, tests of this hypothesis have been constrained by an inability to disc

74 The "income inequality hypothesis" holds that rising income inequality affects

75 This hypothesis, however, has never been tested.

76 Without the exogenous boosting hypothesis, HZ incidence decreased through UVV implement

77 We tested this hypothesis in 850 United States residents during the fir

78 Therefore, we tested this hypothesis in juvenile male songbirds using a comprehens

79 ntal to the competing endogenous RNA (CeRNA) hypothesis in oncology.

80 In this Perspective, we discuss this hypothesis in relation to established principles of elec

81 nable to directly test the stress-reactivity hypothesis in situ.

82 We test this hypothesis in species-rich Mycalesina butterflies that h

83 nt more than one subtype, and we tested this hypothesis in this work.

84 One mechanistic hypothesis involves impaired endothelium-dependent vasod

85 A hypothesis is proposed that this phenomenon defines the

86 The first hypothesis is supported by our optogenetic competition e

87 One hypothesis is that logging influences phosphorus (P) cyc

88 One hypothesis is that P300 modulations reflect the degree o

89 A prominent hypothesis is that people with obesity respond to reward

90 terns of plant speciation, and one intuitive hypothesis is that pollinators affect rates of plant div

91 Our hypothesis is that polynuclear aromatic hydrocarbon (PAH

92 The hypothesis is that training the algorithm to learn the m

93 rotective effect, as proposed by the hygiene hypothesis, is discussed.

94 To test this hypothesis, Lck-Dlx5;Lck-MyrAkt2 transgenic mice were ge

95 was objective response rate (ORR); the null hypothesis (<= 5% ORR) would be rejected within each coh

96 m hypothesis (TMH), the melanism-desiccation hypothesis (MDH) and the photo-protection hypothesis (PP

97 Consistent with this hypothesis, mice transplanted with T-cells co-expressing

98 tion of serum calcium levels, confirming the hypothesis of a calcitriol producing pancreatic neuroend

99 We verified the hypothesis of a differential transmission rate in couple

100 s cell mass to growth rate(1) and Donachie's hypothesis of a growth-rate-independent initiation mass(

101 In this study, we tested the hypothesis of a positive association between plasma ANGP

102 These results support the hypothesis of a potential role of exposure to the plume

103 The findings support the hypothesis of a response of salmon populations to large

104 paport acinus (acute damage), supporting the hypothesis of ACLF.

105 thogen interaction.IMPORTANCE The "pathogen" hypothesis of Alzheimer's disease (AD) proposes that bra

106 levels of cerebral perfusion, supporting the hypothesis of connexin hemichannel-mediated release of s

107 ement method (XFEM), rest on the century-old hypothesis of constancy of materials' fracture energy.

108 up and divergence time estimates support the hypothesis of continental range contraction to a single

109 The data are consistent with the hypothesis of functional coupling of two SERCA2a protome

110 Our results strongly support the hypothesis of molecularly, functionally, and spatially d

111 Results fail to confirm the null hypothesis of no association between BCG vaccination and

112 observed in some cases might corroborate the hypothesis of residual viral antigen-driven chronic arth

113 The hypothesis of this randomized controlled clinical trial

114 organization and contradicts the predominant hypothesis of twisting of microfibrils in plant primary

115 This hypothesis, often credited to Charles Darwin, is a patte

116 We tested this hypothesis on one gene with an exclusively zygotic funct

117 eractions, as a lack of data to evaluate the hypothesis, or be an artifact of scale.

118 two-stage design was used to compare a null hypothesis OS3 of 18% against an alternative of 43%.

119 Contrary to our hypothesis, patients with HFpEF displayed impaired cardi

120 seminated convergence in physical appearance hypothesis posits that long-term partners' facial appear

121 The synaptotrophic hypothesis posits that synapse formation stabilizes dend

122 A recent hypothesis postulates that specially equipped "hub" or "

123 on hypothesis (MDH) and the photo-protection hypothesis (PPH).

124 The resource hierarchy hypothesis predicts that the most important factors limi

125 The music and social bonding (MSB) hypothesis provides the most comprehensive theory to dat

126 ecords from 4,410 Lepidopteran species, this hypothesis receives robust support.

127 mpirical tests of this "biotic interactions" hypothesis remain limited and often provide mixed result

128 eurochemical deficits, such as the monoamine hypothesis, research toward this goal has shifted toward

129 According to the efficient coding hypothesis, sensory systems are adapted to maximize thei

130 However, contrary to the hypothesis, some phage resistance mutations pleiotropica

131 Consistent with our hypothesis, species from drier summers had traits confer

132 The null hypothesis specified a complete response rate of less th

133 The current hypothesis states that when the intracellular "free" iro

134 In support of this hypothesis, studies in animal models as well as human su

135 One hypothesis suggests that cholinergic stimulation of isle

136 se problems develop, the neuroimmune network hypothesis suggests that early-life stress initiates a p

137 Equivocal support to the POLS hypothesis suggests that the link between life history a

138 The second hypothesis suggests these patterns are not intrinsic but

139 ological data, and in contrast to a previous hypothesis, suggests that CytM does not transfer electro

140 re resolved, and better-evaluated TWiG-based hypothesis supports the grouping of dromaeosaurids + tro

141 binomial distribution to create an efficient hypothesis testing algorithm that identifies biomarkers'

142 Here we demonstrate that sequential hypothesis testing on the same dataset by multiple resea

143 a target list of genes before conducting any hypothesis testing or experimental verification.

144 s, namely PCS perturbation intervals and PCS hypothesis testing, to investigate the stability of data

145 es were adjusted for covariates and multiple hypothesis testing.

146 tical uncertainty and the ability to perform hypothesis testing.

147 bistability involves a substantial amount of hypothesis testing.

148 Typically, this is done via hypothesis testing: the statistical properties of the em

149 on, rather than part of an interdisciplinary hypothesis-testing toolkit, limiting their scope and app

150 Two hypothesis tests on the overall mediation effect are pro

151 In addition, the hypothesis that (de)phosphorylation processes drive the

152 The present study tested the hypothesis that 2 weeks of standard, conventional physic

153 We aimed to test the hypothesis that 7 days on a HFHC diet increases IMTG con

154 This study tested the hypothesis that a quantifiable, significant relationship

155 These data do not support the hypothesis that a strategy of leaflet resection (versus

156 These results are consistent with the hypothesis that A2AR ligation is mitoprotective in OA.

157 We tested the hypothesis that A2AR stimulation maintains or enhances m

158 molecular and histologic results support the hypothesis that Acomys has reduced spinal inflammation a

159 address this gap in knowledge by testing the hypothesis that adoption of internally-directed focused

160 ate and multivariate methods, supporting the hypothesis that algorithmic management can maintain the

161 oral order judgment task, we here tested the hypothesis that alpha power reflects the overcoming of a

162 Results support the hypothesis that AM trees respond positively to an inorga

163 through integrin receptors, we examined the hypothesis that an abnormal ECM-integrin receptor axis c

164 es, there has been considerable focus on the hypothesis that anesthetics co-opt the neural mechanisms

165 We test the hypothesis that aneuploidy brings about resistance to ch

166 As this conflicts with the hypothesis that BC200 is a translational suppressor, we

167 after BCG vaccination but do not support the hypothesis that BCG vaccination is a risk factor for pos

168 Here, I outline the hypothesis that cancer-associated perturbations collecti

169 comprise diploid cardiomyocytes, raising the hypothesis that cardiomyocyte polyploidy poses a barrier

170 ates, derived from these models, support the hypothesis that chromatophores constitute a screening me

171 These findings provide support for the hypothesis that cocaine-induced CBF reductions lead to n

172 )) with increased levels of Nrf2 to test the hypothesis that constitutive levels of Nrf2 in the prema

173 eutic strategy against severe Lassa fever, a hypothesis that could be tested in relevant animal model

174 Specifically, we addressed the hypothesis that early in the onset of metabolic diseases

175 red behavioral paradigm to directly test the hypothesis that echolocating bats build internal predict

176 This supports the hypothesis that efferent regulation may be a biological

177 Here, we tested the hypothesis that endothelial cell-initiated signaling is

178 We tested the hypothesis that exposure to the emissions from the volca

179 These findings support the hypothesis that fibrosis, evidenced by increased elastic

180 from wild Phayre's leaf monkeys to test the hypothesis that fluctuations in reproductive hormone con

181 Our data support our hypothesis that functional HCEnCs can be preserved in hy

182 Here, we tested the hypothesis that gene expression profiles of protein-codi

183 We tested the hypothesis that genetic or pharmacological inhibition of

184 lcanic island ideally suited for testing the hypothesis that geomagnetic field behavior is anomalous

185 Our findings support the hypothesis that glutamine may be a key marker for glioma

186 ase activity to cell morphology, support the hypothesis that GTPase signaling dynamics can generate t

187 ther, these findings are consistent with the hypothesis that habitually napping children may have mor

188 locking Fab fragment to test the therapeutic hypothesis that HtrA1 protease activity is involved in t

189 ans morphology in vitro and suggest that the hypothesis that human immunoglobulins may affect C. neof

190 Our results support the hypothesis that hybridization can act as a generative fo

191 trait-dependent diversification to test the hypothesis that hybridization impacts the diversificatio

192 We tested the hypothesis that IAP may induce autophagy which may media

193 Our work raises the hypothesis that impaired mitochondrial calcium transport

194 Collectively, our findings support the new hypothesis that in tauopathies the change in the express

195 r balance on SIC accumulation, we tested the hypothesis that increased soil water storage and transpo

196 ing a candidate gene approach, we tested the hypothesis that individual single nucleotide polymorphis

197 rly relevant in early stages, supporting the hypothesis that invasion of nerves by cancer cells has a

198 These findings support the hypothesis that LC projections to CeA are critical for t

199 s within Sulfolobus islandicus supported the hypothesis that LeuRS-F, but not LeuRS-I, functions as a

200 The current study tested the hypothesis that maternal immunization with DeltagD-2 wou

201 Our data challenge the prevailing hypothesis that membrane fluidity serves as the measured

202 We investigate the hypothesis that mitochondrial Ca(2+) uptake via MCU infl

203 Here, we tested the hypothesis that mood- and sex-dependent alterations in b

204 Our results support the hypothesis that NETs may represent drivers of severe pul

205 We explored the hypothesis that nicotine increases NGF by reducing lung

206 We tested the hypothesis that nonambulatory rest in hunter-gatherers i

207 We found little evidence to support the hypothesis that offspring prioritize their same-sex pare

208 Here we test the hypothesis that one pathway involves hormone mechanisms

209 The aim of this study was to test the hypothesis that phospholemman phosphorylation regulates

210 sport of BDNF through the BBB, we tested the hypothesis that plasma BDNF may be used as biomarker for

211 added amyloid fibers is consistent with the hypothesis that preamyloid oligomers are the most toxic

212 udy provides further evidence to support the hypothesis that primary age-related tauopathy has distin

213 tion modelling, we tested the pre-registered hypothesis that putatively noradrenergic (NA)-dependent

214 Therefore, we sought to test the hypothesis that refined blood transcriptional biomarkers

215 In this study we explore the novel hypothesis that regulation of growth factor receptor tra

216 he Tibetan Plateau, our findings support the hypothesis that repeated glacial and landslide damming i

217 In the current study, we tested the hypothesis that ribitol could also enhance matriglycan e

218 The PROteKT study tested the hypothesis that rosuvastatin can inhibit aminoglycoside-

219 To test the hypothesis that RSV infection promotes inflammation via

220 plement activation in humans have led to the hypothesis that SARS-CoV-2 triggers complement-mediated

221 Results support the hypothesis that self-generated movements underlie adapta

222 In this study, we tested the hypothesis that SGC Gq-coupled receptor (Gq-GPCR) signal

223 termed 'atrophy network mapping' to test the hypothesis that single-subject atrophy maps in patients

224 of sleep in learning and memory, we tested a hypothesis that sleep protects old memories from being f

225 We investigated the hypothesis that SOD3 preserves HA homeostasis by inhibit

226 ary and historical individuals, and test the hypothesis that some A. varius populations have rapidly

227 prototype portable robot, to investigate the hypothesis that the balance of both healthy and chronic

228 rove hygienic selection tools, we tested the hypothesis that the cuticular compounds (Z)-10-tritriaco

229 The hypothesis that the energy sensor AMPK is necessary to o

230 Quantum chemical calculations support the hypothesis that the enhancement of selectivity can be at

231 eophytes but we found little support for the hypothesis that the evolution of the bulb, corm or tuber

232 findings from this work puts forth the novel hypothesis that the immunotherapeutic efficacy of a micr

233 Together, these findings support the hypothesis that the neural mechanisms of visual selectiv

234 trade-off', there was little support for our hypothesis that the physiological costs of childbearing

235 In search of a method we tested the hypothesis that the physiologically impactful events of

236 We addressed this issue by testing the hypothesis that the primate amygdala acts, in part, like

237 The findings are consistent with the hypothesis that the putative zymogens of many trypsin-li

238 Specifically, we test the hypothesis that the relative distance of the alula from

239 Here, we tested the hypothesis that the S-OFF response is mediated by the S-

240 To test the hypothesis that the source partner affects the number of

241 We test the hypothesis that the stability and precision of context a

242 Here we test the hypothesis that the stereotyped group diving and vocal b

243 Here we test the hypothesis that the transformation from motor commands t

244 These findings support the hypothesis that the Warburg effect is a precisely regula

245 Recent studies support the hypothesis that these compositional and mechanical chang

246 In this study, we investigated the hypothesis that these epigenetic alterations act in a fe

247 ath genetic correlation was high (0.84), the hypothesis that they reflect behaviors only differing in

248 Here we test a novel hypothesis that this vertical asymmetry in global proces

249 We tested the hypothesis that underrepresented students in active-lear

250 ties between the two phases, reinforcing the hypothesis that unloading (recovery) may be a good surro

251 We tested the hypothesis that variation in home range size increases R

252 Here, we test the hypothesis that vessel noise level is a driver of distur

253 These findings support the hypothesis that Vpr induces the degradation of a factor,

254 These results support the hypothesis that warming ocean waters will restrict the h

255 The hypothesis that water has a second critical point at dee

256 Our results are consistent with the hypothesis that when stone tip cross-sectional geometrie

257 This observation supports the hypothesis that-in organisms with early X chromosome ina

258 We hypothesised that a recent treatment, metacognitive ther

259 We hypothesised that FGR is associated with reduced placent

260 nism is required for anti-DI activity and we hypothesised that our new lipidized peptide (METx) would

261 We hypothesised that pharmacist provision of the progestoge

262 Past researchers have hypothesised that the bulbous, cormous and tuberous habi

263 We hypothesised that these phenomena were derived from alte

264 a simple method to test an alternative null hypothesis: that lineage-specific genes do have homologs

265 wo central tenets of the biotic interactions hypothesis: that predation is (1) strongest near the equ

266 rprisingly, in contrast to Knudsen's two hit hypothesis, the p.S745L somatic mutation was always on t

267 spective discusses three key aspects of this hypothesis: the role of NAAA in controlling the signalin

268 rs in a single exposure-outcome MR analysis, hypothesising they are due to horizontal pleiotropy.

269 grees-of-freedom are computed, allowing null-hypothesis thresholding at high levels of confidence.

270 orests (here referred to as the more species hypothesis) through increased tree productivity and tree

271 croecological patterns: the thermal melanism hypothesis (TMH), the melanism-desiccation hypothesis (M

272 Using traditional approaches, the time from hypothesis to obtaining the results can be protracted, t

273 Next, we applied the sensitization hypothesis to our model, which predicts that prey with m

274 framework of the uncontrolled manifold (UCM) hypothesis to test two hypotheses: (i) individual motor

275 sted core predictions of the food limitation hypothesis using a controlled experiment that provided s

276 We solve this conundrum by reexamining this hypothesis using the facial images of 517 couples taken

277 We tested this hypothesis using two potential therapeutic strategies to

278 This hypothesis was recently formalised in an agonistic chara

279 Our hypothesis was that compared to controls, mice that had

280 The hypothesis was that daily addition of 1.8g n-3 PUFA to s

281 The underlying hypothesis was that the cells preparing for cell divisio

282 The primary hypothesis was the superiority of the downstream versus

283 To test this hypothesis we use single molecule Forster Resonance Ener

284 To test this hypothesis, we developed a statistical-thermodynamics-ba

285 To test this hypothesis, we developed an automated software-based met

286 To test this hypothesis, we devised a purely visual model in which ne

287 To test this hypothesis, we examined motor-evoked potentials (MEPs) e

288 To test this hypothesis, we exposed adult female Long-Evans rats to 2

289 To test this hypothesis, we extend photosynthetic co-ordination theor

290 In agreement with this hypothesis, we found that, following the intervention, i

291 To test that hypothesis, we infected Pompe cells and then assessed th

292 To test this hypothesis, we infected young adult mice with either of

293 In line with our hypothesis, we provide novel evidence that this noise re

294 To test this hypothesis, we resequenced two 3-4 generation nuclear fa

295 As a first step in testing this hypothesis, we set out to demonstrate that the tricuspid

296 ion, interest is growing in the 'geroscience hypothesis', which posits that manipulation of fundament

297 umptions (e.g., the weak ergodicity breaking hypothesis) which have never been put under a strong tes

298 The exogenous boosting hypothesis, which postulates that reexposure to circulat

299 Here, we confirm this hypothesis with the identification of de novo mutations

300 Such a hypothesis would also contribute to the rapidity and pro