ライフサイエンスコーパス: ibotenic acid

1 The effects of glutamate were mimicked by ibotenic acid.

2 rically, and ACC lesions were generated with ibotenic acid.

3 e injected with the glutamatergic neurotoxin ibotenic acid.

4 ta) through microinjection of the neurotoxin ibotenic acid.

5 schemic procedure, by radio frequency, or by ibotenic acid.

6 ific damage to the VLPO by microinjection of ibotenic acid.

7 r is ablated by the cell-specific neurotoxin ibotenic acid.

8 basalis following a unilateral injection of ibotenic acid.

9 e in Sprague-Dawley rats with the neurotoxin ibotenic acid (10 microg/microl; 0.3 microl / side).

10 tive bilateral lesioning of the SVA neurons (ibotenic acid, 2 microg, 200 nl) blocked the vasodilatio

11 oning of FN neurons by the microinjection of ibotenic acid 5 days before SVA stimulation did not affe

12 Lesions were performed by local injection of ibotenic acid and chronic activation of the ACC by optog

13 la and hippocampus made with the excitotoxin ibotenic acid, and then assessed their recognition abili

14 In the SN pars compacta, both 6-OHDA and ibotenic acid destroyed endogenous dopamine neurons and

15 However, ibotenic acid destruction of SNpr neurons, which should

16 Selective neurotoxins, NMDA for the BLA and ibotenic acid for the CeA, were used to destroy intrinsi

17 udy examined the effects of electrolytic and ibotenic acid (IA) lesions of the medial preoptic area (

18 e expression following bilateral excitotoxic ibotenic acid (IA) lesions of the rat medial prefrontal

19 Excitotoxic ibotenic acid (IBA) causes PVWMI-like lesions when injec

20 In Experiment 1, rats with ibotenic acid (IBO) lesions of the CN failed to show enh

21 ed rats, the FN was stimulated for 1 hr, and ibotenic acid (IBO) was microinjected unilaterally into

22 n NE release in the VMH during hypoglycemia, ibotenic acid (IBO), an NMDA receptor agonist that selec

23 the hippocampus vulnerable to the neurotoxin ibotenic acid (IBO).

24 In the iMnPOx group, 200 nl of ibotenic acid in phosphate buffer saline (5 microg/micro

25 medial septum was selectively lesioned with ibotenic acid in rabbits (Oryctolagus cuniculus), whose

26 Unilateral lesions were made by injection of ibotenic acid in the TRN.

27 Male Long-Evans rats received ibotenic acid-induced lesions of either dorsal or ventra

28 Adult male rats received vehicle or ibotenic acid infusions into the vHPC, using parameters

29 w that cell loss is relatively uniform after ibotenic acid injections into areas CA1 and CA3 and vari

30 cantly by more than 53% (P<0.0001) after the ibotenic acid injections.

31 fore and after injections of the excitotoxin ibotenic acid into the most caudal part of the ventrolat

32 en received either a unilateral injection of ibotenic acid into the nucleus basalis magnocellularis,

33 2 weeks following a unilateral injection of ibotenic acid into the nucleus basalis; however, these e

34 lmost eliminated following microinjection of ibotenic acid into the stimulation sites (P < 0.05) or b

35 lesions of the RVM (n=6) or Vi/Vc (n=6) with ibotenic acid led to the elimination or attenuation of m

36 It was found that ibotenic acid lesion modulated the acute and chronic eff

37 randomly assigned to either sham (iSHAM) or ibotenic acid lesion of the MnPO (iMnPOx).

38 Ibotenic acid lesion of the mPFC was effective, damaging

39 Rats with extensive ibotenic acid lesions centered in the gustatory zone of

40 Rats received ibotenic acid lesions in the MeA or central amygdala (Ce

41 In this study, ibotenic acid lesions in the NAcc core increased the lik

42 Ibotenic acid lesions in the NAcc shell did not affect p

43 In the present study, the specificity of ibotenic acid lesions into areas CA1 and CA3 and colchic

44 AD+ terminals in DLM was strongly reduced by ibotenic acid lesions of area X.

45 Rats with ibotenic acid lesions of CN and control rats first learn

46 ined in a second group of three animals with ibotenic acid lesions of GPe.

47 iment, we compared the effects of bilateral, ibotenic acid lesions of OFC or BLA (or SHAM) on visual

48 postnatal age, received selective bilateral ibotenic acid lesions of the amygdala (N = 8) or hippoca

49 monkeys, 11 of which had previously received ibotenic acid lesions of the amygdala and seven of which

50 ntrast, the inhibitory learning of rats with ibotenic acid lesions of the amygdala central nucleus (C

51 eys (Macaca mulatta) that received bilateral ibotenic acid lesions of the amygdala or the hippocampus

52 Selective ibotenic acid lesions of the amygdala, but not the hippo

53 repared monkeys with selective fiber sparing ibotenic acid lesions of the amygdala.

54 rhesus monkeys were prepared with bilateral ibotenic acid lesions of the amygdaloid complex and the

55 Similarly, ibotenic acid lesions of the dentate gyrus eliminated Kv

56 We found that ibotenic acid lesions of the entorhinal cortex eliminate

57 The results show that bilateral ibotenic acid lesions of the gustatory thalamus eliminat

58 Rats with bilateral ibotenic acid lesions of the gustatory zone of the parab

59 s were tested: normal controls, monkeys with ibotenic acid lesions of the hippocampal formation (H),

60 Rats with radio-frequency or ibotenic acid lesions of the hippocampus and rats with r

61 The effects of ibotenic acid lesions of the hippocampus on overshadowin

62 eived neonatal (15 +/- 3 days old) bilateral ibotenic acid lesions of the hippocampus or amygdala, or

63 Half of the trained rats received ibotenic acid lesions of the hippocampus.

64 Food-restricted rats with ibotenic acid lesions of the lateral hypothalamus (LH) a

65 e lateral internal medullary lamina (IML) or ibotenic acid lesions of the lateral intralaminar nuclei

66 The present study examines the effects of ibotenic acid lesions of the medial amygdala, the bed nu

67 nt study examined the influence of bilateral ibotenic acid lesions of the medial or lateral PBN on th

68 The present study examined the effect of ibotenic acid lesions of the medial preoptic area (mPOA)

69 The present study evaluated the effects of ibotenic acid lesions of the medial preoptic area (mPOA)

70 Bilateral ibotenic acid lesions of the nucleus basalis interfered

71 Rats with ibotenic acid lesions of the parabrachial nucleus (PBN)

72 Electrolytic and ibotenic acid lesions of the PMd have been shown to redu

73 f the nucleus of the solitary tract (NST) or ibotenic acid lesions of the pontine parabrachial nuclei

74 ere performed before and up to 3 weeks after ibotenic acid lesions of the preoptic forebrain in three

75 al visual cortical ablations and ipsilateral ibotenic acid lesions of the substantia nigra pars retic

76 perature, and activity in rats of restricted ibotenic acid lesions of the ventral or dorsal SPZ that

77 ydroxydopamine lesions of the A5-7 groups or ibotenic acid lesions of the ventrolateral periaqueducta

78 However, neither NMDA lesions of the AHN nor ibotenic acid lesions of the VMH reduced freezing in sho

79 Six of the monkeys then received ibotenic acid lesions restricted to the hippocampal form

80 The present study used bilateral ibotenic acid lesions to evaluate the role of a neighbor

81 The present study used bilateral ibotenic acid lesions to examine the role of the gustato

82 Large unilateral ibotenic acid lesions were made in several structures co

83 adult monkeys received bilateral hippocampal ibotenic acid lesions, and six control subjects underwen

84 ved either bilateral amygdala or hippocampus ibotenic acid lesions, or a sham surgical procedure at 2

85 Macaca mulatta) was assessed after bilateral ibotenic acid lesions.

86 After this, half of the animals received ibotenic acid lesions.

87 Two experiments investigated the effects of ibotenic-acid lesions of the hippocampus on food-rewarde

88 Rats with ibotenic-acid lesions targeted to the lateral PBN (PBNx)

89 hesis, bilateral electrolytic or excitotoxic ibotenic acid MG nuclear lesions were induced, and multi

90 performed unilaterally by local injection of ibotenic acid (microg/microl, 90 nl) 10 days prior to re

91 psychoactive substances, such as psilocybin, ibotenic acid, muscimol and lysergic acid amides.

92 Rats microinjected with ibotenic acid, muscimol, or a CRF ASO into the CeA befor

93 tudy, rats received two injections of either ibotenic acid (N=12) or vehicle (N=8), targeting the con

94 oduced either by infusions of the neurotoxin ibotenic acid or by radiofrequency current, produced a s

95 y localized injections of neurotoxins (e.g., ibotenic acid or colchicine) into targeted subregions of

96 One week later, ibotenic acid or sham lesions were made in the mPFC cent

97 the Ce of hamsters were either lesioned with ibotenic acid or sham-lesioned.

98 In the SN pars reticulata, ibotenic acid reduced the number of neurons and high-aff

99 ,7-DHT affected [3H]glyburide binding, while ibotenic acid reduced the number of VMN neurons and abol

100 ions of Vc with a soma-selective neurotoxin, ibotenic acid, significantly reduced inflammation-induce

101 mPFC lesions (prelimbic/infralimbic regions; ibotenic acid) using a variant of a non-match-to-sample

102 l intake of rats with PBN lesions induced by ibotenic acid, using multiple models of salt appetite.

103 complete bilateral damage to GC produced by ibotenic acid was insufficient to disrupt postsurgical e

104 iment, a single injection of the neurotoxin, ibotenic acid, was injected unilaterally into the ventra

105 y an ischemic procedure, radio frequency, or ibotenic acid were tested on a simple, two-choice object

106 OHDA), 5,7-dihydroxytryptamine (5,7-DHT) and ibotenic acid were used to elucidate the cellular locati

107 conditions and also after MAN lesioning with ibotenic acid, were used to examine the functional role