ライフサイエンスコーパス: idea

1 to abstract concepts, as well ("grasping an idea").

2 idea production (the ability to generate an idea).

3 We demonstrate a benchtop prototype of this idea.

4 ve signal, but no study directly tested this idea.

5 terest since Anderson's 1973 ground-breaking idea.

6 ytical and simulation models to examine this idea.

7 ldwide to develop various extensions of this idea.

8 nd comprehend an unbounded number of complex ideas.

9 drops, and rodents, illustrate the essential ideas.

10 erful sense of connection between people and ideas.

11 onsiderations when empirically testing these ideas.

12 gic researchers with diverse backgrounds and ideas; 2) promote an inclusive environment at the SER An

13 To get an idea about the most probable microporous supramolecular

14 Herein, we explore strategies to extend the ideas about ancillary groups that have been developed fo

15 Ideas about how this circuit works are based largely on

16 The ideas about how to develop an algorithm to exploit the t

17 We suggest that ideas about liking (e.g., evaluations of categories or o

18 aluations of particular exemplars), and that ideas about liking may facilitate mental travel beyond t

19 First, relatives negotiated conventional ideas about normalcy and positioned themselves as living

20 mmarize new evidence challenging century-old ideas about the development of stomach and intestine lat

21 to analyze three scRNA-seq data sets, where iDEA achieves up to five-fold power gain over existing G

22 The power gain brought by iDEA allows us to identify many pathways that would not

23 highlighting collaborations and influential ideas along the way.

24 Cross-talk and sharing of ideas among participating experts in basic science and c

25 etabolic control of development is not a new idea and can be traced back to Joseph Needham's 'Chemica

26 oretical and mathematical work supports this idea and provide a blueprint for future investigations.

27 In 1994, a convergence of ideas and collaborative research orchestrated by Randy S

28 n immune responses to infection, the overall ideas and descriptions of model uses can be applied to a

29 es have an important role in the exchange of ideas and knowledge within the scientific community.

30 eas evolved, and I discuss criticisms of the ideas and our responses to critics.

31 pothalamic-BAT interactions, we aim to raise ideas and provide a new perspective on this circuit and

32 Twitter to communicate new results, discuss ideas and share techniques is becoming central.

33 tepped aside and workers discussed problems, ideas, and goals regarding their work (vs.

34 etwork, share research, learn new skills and ideas, and initiate collaborations.

35 ad-scale patterns in the movement of people, ideas, and material culture in Eurasian prehistory.

36 overnment responses to COVID-19 when people, ideas, and media move across borders.

37 Papers that build on very recent ideas are NIH funded less often than are papers that bui

38 Papers that build on novel clinical ideas are not more often NIH funded than are papers that

39 r endeavor never change, and of how some new ideas are perhaps not as new as we would like to think.

40 By using IDEAS as our integrative and discriminative epigenome an

41 The main idea behind SR seems quite unorthodox - it proposes that

42 Supporting this idea, beta-HPV's 8E6 protein attenuates p53 accumulation

43 Here, we further develop this idea by considering how simulation noise may be adaptive

44 Here, we test this idea by constructing and exploring a kinetic transport m

45 We tested this idea by creating different types of memory task: a seque

46 In vitro data support this idea by demonstrating the ability of the beta-HPV E6 pro

47 We substantiate this idea by simulating multiple proposed metabolisms for ear

48 Here, we tested this idea by training rats to choose between different pellet

49 We test these ideas by identifying allelic differences between superge

50 we can suggest personalized, out-of-the-box ideas by identifying pairs of concepts, which have uniqu

51 We test these ideas by using observations from a laboratory-in-the-fie

52 pproach to annotate a set of genes, the same idea can be extended to explore the enrichment of functi

53 By integrating DE and GSE analyses, iDEA can improve the power and consistency of DE analysi

54 erence data, computed network components and IDEAS chromatin segmentations are companion resources to

55 In support of this idea, cleavage of transcription factor NRF1 is known to

56 from Ca(v)2.3 competent mice, supporting the ideas derived from previous work in the bovine retina th

57 we are then able to map, over time, how the ideas developed in a given field in a certain time perio

58 More recent ideas emphasize roles for positive emotionality and impu

59 ofessional contexts in which these and other ideas evolved, and I discuss criticisms of the ideas and

60 The idea expands our understanding of grid cells, suggesting

61 cinogenesis is evaluated and future research ideas explored.

62 nstrate in four experiments (n = 1,900) that ideas expressed with generic-you increased resonance.

63 Even though Needham's ideas fell by the wayside with the advent of genetic stu

64 The key idea for breaking this bottleneck pursued in this work i

65 lity enables developers to quickly prototype ideas for computational mass spectrometry projects in on

66 infected patients seems like one of the best ideas for controlling the situation.

67 ardized approach to assessment, and generate ideas for future research.

68 Our work provides new design ideas for the utility of phenolate MC dyes, given that t

69 m patients with stage III CC included in the IDEA France phase III study (ClinicalTrials.gov identifi

70 across 12 countries in the CALGB/SWOG 80702, IDEA France, SCOT, ACHIEVE, TOSCA, and HORG trials, who

71 To do this, we combine ideas from Alan Turing's work on pattern formation with

72 prove to be transformational in accelerating ideas from bench to bedside, maximizing scientific disco

73 Extensions of these ideas from current tight binding models to continuum the

74 Drawing on ideas from information theory, an efficient retinal code

75 dynamics and that a stronger integration of ideas from network theory may provide insight into metap

76 Here, we use ideas from the mathematical theory of self-assembly to e

77 To this end, we leveraged recent ideas from theoretical neurobiology to understand the hu

78 necessitates a common language to integrate ideas from these fields.

79 This idea has not received broad support, mostly because of a

80 Although these ideas have informed the field for decades, they have not

81 This idea implies a set of empirical predictions, which we te

82 Our goal was to test this idea in a more definitive way using genetic knock out mi

83 We tested this idea in a mouse model of Enterococcus faecium gastrointe

84 We tested this idea in Xenopus laevis photoreceptors, and found that tr

85 ticity, as defined by Huckel's rule, are key ideas in organic chemistry, and are both exemplified in

86 We present these ideas in the context of rat serotonergic raphe neurons,

87 een the consequences of publishing erroneous ideas in the first half of the 20th century and doing so

88 We implement our ideas in the minigraph toolkit and demonstrate that we c

89 These ideas include homology search, guilt-by-association (GBA

90 The idea is based on the insertion of opportunely designed n

91 cork material quality, directly testing this idea is hindered in part because it is not known which g

92 One idea is that rules could simplify these computations.

93 The main idea is that the dynamics of a chaotic dynamical system

94 The main idea is that, for each target gene, we use an And/Or tre

95 The idea is to first discover certain input-output relations

96 The main idea is to model each stable (durable) state of a given

97 Its fundamental idea is to use multiple energy functions as multi-object

98 ituted system, required to substantiate this idea, is lacking.

99 Phage therapy is an old idea, long practiced in eastern European countries and g

100 NA-seq to decompose integrative cis-element (IDEAS) models that were derived from whole-tissue epigen

101 These ideas motivate the hypothesis that carbon export in wood

102 s well as providing further evidence for the idea of a continuum of psychosis in the healthy, nonclin

103 In the field of cancer treatment, the idea of a cure-all silver bullet has long been abandoned

104 To address these questions, we introduce the idea of a domain-general "strategic mindset." This minds

105 Functionally the latter underlines the idea of a primarily calcitic character of the lens becau

106 Recently, the idea of a solid-electrolyte inductive effect has been pr

107 aB DNA consensus sequence, strengthening the idea of an association between the two proteins.

108 Our results support the idea of caves as natural laboratories for the study of p

109 tiple human disorders, making attractive the idea of chemically modulating it with therapeutic purpos

110 These results support the idea of combined prosthetic and natural vision in restor

111 The idea of combining the size and shape selectivity of poro

112 We propose a new method based on the idea of delegating regressors for predicting the soil ra

113 ted in failing hearts, only recently has the idea of disrupting altered transcription by targeting ch

114 ed cross-validation (cnCV) that combines the idea of feature stability from differential privacy with

115 D topology laf, a model of which gave us the idea of foldable network topologies, as the laf-net can

116 olloids in water defy the intuitively simple idea of forming crystals from oppositely charged partner

117 The idea of generating new spectral information using passiv

118 The underlying idea of GOxploreR is to exploit a graph-theoretical pers

119 scuss the importance of the findings for the idea of hierarchical control and the notion of muscle co

120 earned visual information and we have a good idea of how visual memories can guide individuals along

121 nthetic compounds that were created with the idea of investigating their biological actions.

122 lysis techniques that have been built on the idea of large-scale multivariant analysis and provide em

123 Feedback is a general idea of modifying system behavior depending on the measu

124 this paper are theoretical, to motivate the idea of multiplexing, we provide experimental evidence t

125 served microscopically in the 1840s, but the idea of oxidative phosphorylation (OXPHOS) within mitoch

126 experimental results are consistent with an idea of pressure-induced low to high density liquid tran

127 The idea of resolving dispute through the exchange of argume

128 We adopt the idea of sequential coordinate-wise descent to NMF to inc

129 lications for quantum computers is Feynman's idea of simulating quantum systems with many degrees of

130 The key idea of SneakySnake is to reduce the approximate string

131 We used the idea of synergic control and the framework of the uncont

132 study, for the first time, we have used the idea of synergic control and the framework of the uncont

133 e results show, for the first time, that the idea of synergic control is applicable to individual mus

134 1979, Richard Law introduced the conceptual idea of the 'Darwinian Demon': an organism that simultan

135 The core idea of the algorithm is to retrieve domain boundary loc

136 nted to gather recent results supporting the idea of the central role of sharing agency in socioaffec

137 visualization (a presentation of the general idea of the molecular and structural organization of the

138 The central idea of this joint effort is to highlight key parameters

139 These experiments support the idea of VcPilQ as a potential druggable target and provi

140 Here, we apply the idea of worldviews to cognition and rationality in trans

141 t a framework that draws heavily on existing ideas of dual processes in memory in order to make predi

142 c drugs has the potential to reconfigure our ideas of how target-based therapeutic molecules can work

143 The key ideas of our method are the formation of compressed zone

144 This article discusses a few ideas of this sort related to chromosome biology, to ill

145 The proposed framework unites many ideas of tinnitus pathophysiology and may catalyze coope

146 Ideas on hominin evolution have long invoked the emergen

147 enes manipulate homologous recombination and ideas on how the resulting dysregulation and inhibition

148 There are many contrasting ideas on the effectiveness of influenza vaccination on C

149 These results reconcile competing ideas on the opening of the rift system by highlighting

150 Two studies tested this idea, one targeting compassion for the self and one targ

151 esses that help promote memory for a general idea or concept can also hinder more detailed memory jud

152 To test this idea, peripheral blood ML NK cells were modified to expr

153 (the novelty and usefulness of an idea) with idea production (the ability to generate an idea).

154 The method exploits an idea proposed in 1961(10) but not previously realized ex

155 , allowing the field to comprehensively test ideas proposed over a century ago and generate many new

156 Although synthetic lethality is not a new idea, recent advances, including CRISPR-based gene editi

157 Here we discuss some of the key ideas, strategies, auxiliary techniques, and innovations

158 or to the investigation of a plethora of new ideas such as branched flow in nonlinear media, in curve

159 We highlight combinations of NNs with other ideas such as permutationally invariant polynomials or s

160 oach to separations will emerge based on the ideas, technologies, and open scientific questions prese

161 We present interpretations of the idea that "epidemiologists count" in response to the cur

162 ulence is context-dependent and bolsters the idea that "pathogen" is a status and not an identity.

163 genetic ties to the eukaryotes, supports the idea that a critical endosymbiosis between an archaeal h

164 The idea that a virus may play a role in the development of

165 Our results support the intuitive idea that acute isolation causes social craving, similar

166 Our results support the idea that AI-2 serves as a widely used signaling molecul

167 These findings challenge the idea that alpha-band activity is directly involved in ta

168 These characteristics contradict the idea that alpha-band directly reflects automatic tactile

169 In this review, we put forward the idea that alterations in prefrontal cortex architecture

170 and simulation modeling further support the idea that altered morphology of the coronoid process may

171 The central idea that an episode of mental disorder arises from caus

172 data presented here are compatible with the idea that applying different TMS currents to the cerebra

173 Our results support the idea that ascribes to PFo an important role for behavior

174 dies of blind and sighted people support the idea that azimuthal spatial bisection in frontal space r

175 Our results support the idea that birds can distinguish colors throughout tetrac

176 ributed to extant humans and may support the idea that blood perfusion of these tissues increased ove

177 Our data, therefore, support the idea that both germline and soma components of the ejacu

178 Collectively these results support the idea that brain-derived estradiol in females may serve i

179 kely to be closely related and underlies the idea that cell migration operates by a common set of phy

180 Our findings corroborate the idea that changes in atmospheric CO(2) levels played a d

181 Collectively, our work reinforces the idea that changes in mitochondrial gene expression are k

182 y replicated evolutionary events support the idea that co-obligate associations initiate in a predict

183 ContamLD leverages the idea that contaminants should have haplotypes uncorrelat

184 delta spontaneous IPSCs, consistent with the idea that deactivation and local GABA actions drive delt

185 Our findings support the long-suspected idea that depth-dependent mixing is a spatially and temp

186 ensitive GABAergic afferents and support the idea that different GABAergic pathways to the VTA contro

187 al factors with evidence also supporting the idea that DNA methylation may modify the risk of environ

188 As such, our findings strengthen the idea that dopamine can modulate locomotor behavior both

189 Our results are in contrast to the idea that effects of inbreeding generally depend on ecol

190 The result supported the idea that elongation of glycan chains has to proceed fro

191 Examples include the idea that fasting when feverish ("starving a fever") can

192 Concerningly, and consistent with the idea that folk wisdom challenges scientific expertise, w

193 Current findings support the idea that for EsxA to interact with host membranes, EsxA

194 These studies provide direct support for the idea that Gag binding to Psi specifically promotes nucle

195 or asymmetry in a vertebrate and support the idea that haploinsufficiency for genes in a core develop

196 Although previous evidence has supported the idea that human height could be a sexually selected trai

197 These results support the idea that increased cortical broadband gamma activity le

198 robust GluA2 expression, consistent with the idea that individual synapses have both CP-AMPARs and Ca

199 The idea that infectious agents in the brain have a role in

200 Our framework rests on the idea that information can alter people's action, affect

201 These results support the idea that inhibiting LHb projections to the DRN provides

202 Here, we discuss the emerging idea that m(6)A could also coordinate the transport, loc

203 Our results support the idea that MCs and TCs comprise functionally distinct pat

204 Our findings support the idea that meiotic genes, in addition to their convention

205 Cultural stereotypes such as the idea that men are more suited for paid work and women ar

206 his study provides empirical support for the idea that mobile phones are a vehicle for sustainable de

207 While these results support the idea that modification of innate immune signalling by ge

208 causing mutations have been dominated by the idea that most pathogenic mutations are disruptive at a

209 These results support the idea that MTCs contribute different aspects to encoding

210 Here we present evidence supporting the idea that MTD may not always be the best approach and of

211 models for repeat expansion and supports the idea that MutLgamma may be a useful druggable target to

212 of birch bark tar, art, and shell beads, the idea that Neanderthals were cognitively inferior to mode

213 Together, our findings support the idea that neuronal maturation requires regulation of pro

214 natural human brain network and support the idea that neurons that wire together die together.

215 These finding score against the idea that non HPC memory storage requires a period of in

216 Our results support the idea that Npas1(+)-Nkx2.1(+) neurons are a distinct GPe

217 ichiganensis against E. coli, supporting the idea that nutrient competition is the primary interactio

218 inactivating properties in vitro support the idea that oral rinsing might reduce the viral load of sa

219 We discuss the idea that oxidation of conserved cysteine residues and p

220 reduced linear growth rates, supporting the idea that partitioning translation to specific times of

221 hibition by PAX is best characterized by the idea that PAX gains access to the channel through the ce

222 These findings support the idea that periodontal inflammation promotes metastasis o

223 The idea that predictions shape how we perceive and comprehe

224 These results support the idea that previous social context is relevant for the de

225 ese cell lines, which is in keeping with the idea that RalGAPA1 deficiency causes a constitutive acti

226 previous computational model, supporting the idea that recurrent inhibition may function to reduce tr

227 rovides quantitative evidence to an original idea that removal-driven trait changes can dampen recove

228 th pacing switched off, we propose the novel idea that RMH pacing causes reverse-remodelling.

229 These findings also support the idea that Sestrins are a molecular mediator of hormesis,

230 We consider here the idea that SiN perception is linked to a more general abi

231 This supports the idea that social interactions among predators can reduce

232 Here, we tested the idea that social learning can benefit from any available

233 Our results support the idea that spatial variation in predator communities alte

234 Here we explore the idea that stochasticity of cell fate choice during tissu

235 ized by the efficient market hypothesis, the idea that stock prices fully reflect all available infor

236 These data support the idea that tau preferentially spreads to specific cortica

237 Our results support the idea that TFEB-mediated tau exocytosis serves as a clear

238 This lends support to the idea that the 'toxic' Y chromosome can create a mutation

239 s in cultural evolution have put forward the idea that the early modern revolutions may be the produc

240 resistance than CPE-K alone, supporting the idea that the electroactive bacteria and the conjugated

241 Our data do not generally support the idea that the germline is prioritized over soma, at leas

242 Our findings support the idea that the Moran effect is low in species where the p

243 Consistent with the idea that the NPC specifically modulates clock function,

244 The reaction development was guided by the idea that the productivity of catalysts employing BrettP

245 This phylogenetic topology supports the idea that the radiodont and megacheiran frontalmost appe

246 This finding reinforces the idea that the reciprocally connected GPe-STN network pla

247 Altogether, data presented here support the idea that the representation of taste qualities in GC of

248 Our results reinforce the idea that the reproducibility of the interaction, not ba

249 Our findings are consistent with the idea that the research productivity of women, especially

250 In addition, our data bring the novel idea that the respiratory rhythm might take part in the

251 These data support the idea that the retina reproduces brain neurodegeneration

252 These behavioral changes support the idea that the shaking signal serves to generally increas

253 cer of beta cell replication, supporting the idea that the use of young blood factors may be a useful

254 gs are therefore consistent with the general idea that the visual system samples light over prolonged

255 culum and cytosol have led to the prevailing idea that these pathways require the activity of Hsp70 c

256 s on EBOV, we found evidence contrary to the idea that these small RNA products function as miRNAs.

257 d upon C-terminus truncation, supporting the idea that these two regions are close in three-dimension

258 The idea that this joining region directly interacts with LT

259 s (MD) simulation studies have supported the idea that this monovalent ion reduces agonist binding by

260 The idea that tip-to-base conduit widening has a nonadaptive

261 The idea that tropical forest and savanna are alternative st

262 Our results are consistent with the idea that TRPC3 channels expressed by cerebral VSMCs con

263 They also support the idea that Vav2 could represent a viable drug target.

264 Modelling supports the idea that widespread marine anoxia was induced by a gree

265 We also find no support for the idea that women earn less because they place more import

266 The bioscaffold design is based on the idea that, if the excess proinflammatory cytokines are s

267 benefits has its origins in the speculative ideas that are more than a century old, yet remain large

268 Finally, I discuss the key theoretical ideas that have emerged from these modeling studies and

269 ded less often than are papers that build on ideas that have had a chance to mature for at least 7 y.

270 elicene as benchmarks contesting established ideas that molecular mass growth processes to PAHs trans

271 Contrary to that idea, this Tutorial Review will present evidence showing

272 In this paper, applying the density scaling idea to an associated liquid 4-methyl-2-pentanol used as

273 We also apply iDEA to analyze three scRNA-seq data sets, where iDEA ac

274 es, gene therapy has advanced from a logical idea to becoming a clinical reality for several of the m

275 We broaden this idea to discuss potential relationships between engrams

276 anisms of current immunotherapies, and fresh ideas to develop better treatments in a variety of thera

277 ps to discuss progress, challenges, gaps and ideas to facilitate the development of biomarkers and en

278 courage dialogue between providers, offering ideas to improve safety in solid organ transplantation w

279 mett-Teller (BET) theory extended Langmuir's ideas to multilayer adsorption.

280 esistant organisms, policymakers are seeking ideas to promote development of novel antibiotics.

281 tegrative and scalable computational method, iDEA, to perform joint DE and GSE analysis through a hie

282 Importantly, iDEA uses only DE summary statistics as input, enabling

283 However, formal validation of this idea using in vivo models is still missing.

284 We tested this idea using unilateral optogenetic activation of neurons

285 This idea was also generalized to extract characteristic k-me

286 Consistent with this idea we identified six distinct community classes that c

287 From this idea we implement a constructive procedure that reveals

288 Consistent with this idea, we also find that the dsRNA binding position is di

289 To test this idea, we examined interactions between components of the

290 To test this idea, we recorded from neurons in 3 regions linked to de

291 To test this idea, we used an in vitro motility assay, where actin fi

292 Motivated by these ideas, we examined whether synaptic inhibition changes o

293 ldwide); however, to more clearly illustrate ideas, we focus on the example of a small scale college

294 ortance of diversity and to offer initiative ideas, which should be centered around inequity stemming

295 the NIH succeeds in funding work with novel ideas, which we term edge science.

296 eavage rates that supports these mechanistic ideas while offering guidance to allow rational design o

297 We illustrate the benefits of iDEA with extensive simulations.

298 We explore these ideas with two case studies showing what can be learned

299 creativity (the novelty and usefulness of an idea) with idea production (the ability to generate an i

300 rsity, Equity, Anti-Racism, and Science (Epi IDEAS) Working Group, we recommend 4 goals for the SER A