ライフサイエンスコーパス: idiosyncratic

1 t been agreed on and seem multifactorial and idiosyncratic.

2 licitation activity among species was highly idiosyncratic.

3 ners changed because species' responses were idiosyncratic.

4 l patterns of firing rate change were highly idiosyncratic.

5 tion of whether adaptive evolution is indeed idiosyncratic.

6 Hence, eating patterns are idiosyncratic.

7 Aesthetic experience seems both regular and idiosyncratic.

8 r injury have been recognized: intrinsic and idiosyncratic.

9 s in cerebral cortex, some properties appear idiosyncratic.

10 The idiosyncratic 6-exon organization of the gene is shared

11 responses to this phenomenon appear largely idiosyncratic, a wealth of basic research on this topic

12 ual mutations, on the other hand, are highly idiosyncratic across genetic backgrounds, revealing perv

13 e subjective appraisals appears to be highly idiosyncratic across individuals.

14 It is possible that coronavirus has an idiosyncratic action on receptors involved in chemosensi

15 The idiosyncratic activation of mast cells (MCs) in response

16 suggested that the LeuRS CP1 domain required idiosyncratic adaptations to confer editing activity ind

17 ps, suggesting that these climates allow for idiosyncratic adaptations.

18 Idiosyncratic adverse drug reactions (ADRs) are one of t

19 Idiosyncratic adverse drug reactions (IADRs) encompass a

20 involvement of reactive metabolites in many idiosyncratic adverse drug reactions (IADRs).

21 Idiosyncratic adverse drug reactions are unpredictable,

22 This provides an explanation for HLA-linked idiosyncratic adverse drug reactions, namely that drugs

23 er is well known but cannot account for most idiosyncratic adverse drug reactions.

24 This range was idiosyncratic and applied to all movements regardless of

25 under climate change is likely to be highly idiosyncratic and difficult to predict.

26 ikely to be geographically and taxonomically idiosyncratic and difficult to predict.

27 evolution of risk-taking in the presence of idiosyncratic and environmental risks to the example of

28 t the species recovery of TMCF after fire is idiosyncratic and follows multiple pathways.

29 pattern across all communities, or are they idiosyncratic and hard to predict from one ecosystem to

30 However, species' range shifts are often idiosyncratic and inconsistent with climatic shift predi

31 These changes are idiosyncratic and occur at different times in each taxa.

32 therefore frequently reversible, others are idiosyncratic and thus unexpected.

33 Liver damage is in most cases idiosyncratic and unpredictable, and it is generally unr

34 acking, whereas MD network activity was more idiosyncratic and, moreover, showed lower reliability wi

35 However, proteolysis cleavage can be idiosyncratic, and it is possible that natural analogues

36 ermit successful invasions have often seemed idiosyncratic, and the key biological traits identified

37 Changes were idiosyncratic, and were not explained by changes in abun

38 nisotropy in perception, we found only small idiosyncratic anisotropies in smooth pursuit eye movemen

39 This finding also implies that the idiosyncratic arrays of additional tertiary contacts obs

40 al and biological changes, is as complex and idiosyncratic as the brain itself, qualitatively changin

41 provides a good estimate of DV and explains idiosyncratic aspects of the decision-making process tha

42 together, vertical OKN was characterized by idiosyncratic asymmetries that remained consistent for a

43 resentations of facial attractiveness convey idiosyncratic attractiveness preferences.

44 levels of inorganic mercury (Hg(2+)) develop idiosyncratic autoimmune disease associated with defecti

45 The COVID-19 economic crash is idiosyncratic because of its virtual standstill of econo

46 t cataloging TE diversity and dissecting the idiosyncratic behavior of individual elements are crucia

47 tionally, mWSD offspring displayed increased idiosyncratic behavior, which was related to alterations

48 tasks have repeatedly been shown to lead to idiosyncratic behaviors that cause varying degrees of ta

49 es in brain structure and physiology produce idiosyncratic behaviors.

50 , establishing the underlying causes for its idiosyncratic behaviour across living kingdoms has prove

51 h the tendency to respond relative to an own idiosyncratic bias, with stronger alpha leading to respo

52 at alpha power reflects the overcoming of an idiosyncratic bias.

53 processes needed to overcome an individual's idiosyncratic bias.

54 rtantly, to understand the interplay between idiosyncratic biases and contextual (temporary) biases i

55 These idiosyncratic biases and their neural underpinnings are

56 otential candidate mechanism reflecting such idiosyncratic biases could be spontaneous alpha band act

57 erably across a number of domains, producing idiosyncratic biases in the appearance of ambiguous figu

58 genomic road leading to recurrence is highly idiosyncratic but can be broadly classified into linear

59 We hypothesized that the idiosyncratic categorical representations of the continu

60 ing to the most reduced plastomes, and a few idiosyncratic changes elsewhere, allowing us to conclude

61 of alpha-satellite HORs, with characteristic idiosyncratic changes in alpha-satellite HORs for each s

62 -dependent signaling with substance P causes idiosyncratic changes in dynamic Ca(2+) signal parameter

63 ities of both plants and pollinators exhibit idiosyncratic changes when experimentally manipulating t

64 and progression, but they also highlight the idiosyncratic character of the tumor context.

65 Rather, it is a variant and idiosyncratic characteristic of some languages, mostly E

66 Regression models will tend to fit to the idiosyncratic characteristics of a particular sample and

67 re assembled in a serial fashion to give the idiosyncratic chlorodienes by an unprecedented site-sele

68 riment, in which the settings are symmetric, idiosyncratic choice bias is expected to emerge from the

69 We thus argue that idiosyncratic choice bias reflects the microscopic dynam

70 Here we quantify idiosyncratic choice biases in a perceptual discriminati

71 r diverse circumstances rather than in rare, idiosyncratic circumstances as in actors (animals) who d

72 ndition to spiral cleavage and one other to "idiosyncratic" cleavage; this arrangement is consistent

73 ncestral within the Bilateria, and spiral or idiosyncratic cleavages, mosaic development, and schizoc

74 these results demonstrate a central role for idiosyncratic cognitive processing in how arousal system

75 eline resting-state connectivity can predict idiosyncratic combination of these components.

76 Idiosyncratic combinations of reductive dehalogenase (rd

77 variables from trial-to-trial, each cell had idiosyncratic combinations of response properties.

78 ls that kanamycin B stabilizes a non-native, idiosyncratic conformation of the riboswitch that inhibi

79 D4 T cell loss to AIDS-type disease; nor the idiosyncratic constellation of immunological and clinica

80 A subset of human neurons harbors idiosyncratic copy number variants (CNVs, "CNV neurons")

81 t modeling of a common information space and idiosyncratic cortical topographies, and discuss implica

82 se a consensus on evidence-based rather than idiosyncratic criteria, including clear guidelines on re

83 and Msn4, which respond by initiating rapid, idiosyncratic cycles into and out of the nucleus.

84 of daily cost variation not attributable to idiosyncratic daily changes within patients.

85 n extreme of the normal range or as-possibly idiosyncratic-deviation from normal functioning.

86 Interestingly, there were idiosyncratic differences among asymptomatic cases in th

87 rmining the susceptibility of individuals to idiosyncratic DIH.

88 or pediatric populations on the incidence of idiosyncratic DILI (iDILI) that may develop independentl

89 We describe here cases of idiosyncratic DILI ALF enrolled during a 10.5-year perio

90 suitable preclinical models for the study of idiosyncratic DILI and its pathogenesis is poorly unders

91 Idiosyncratic DILI is a relative rare hepatic disorder b

92 Furthermore, idiosyncratic DILI is not a single disease entity but ra

93 Idiosyncratic DILI was shown to have an important dose-d

94 We associated idiosyncratic DILI with rs2476601, a nonsynonymous polym

95 onship between daily dose of medications and idiosyncratic DILI, we conducted a study with two aims.

96 have not associated any genetic factors with idiosyncratic DILI.

97 the causes, risk factors, and mechanisms of idiosyncratic DILI.

98 y doses of oral prescription medications and idiosyncratic DILI.

99 ting the relationship between daily dose and idiosyncratic DILI.

100 terations in immune regulation contribute to idiosyncratic DILI.

101 these patterns to neutral processes such as idiosyncratic dispersal timing and trajectories.

102 Moreover, the patterns of idiosyncratic distortions of network synchrony relative

103 previously unrecognized ASD characteristic: idiosyncratic distortions of the functional connectivity

104 To determine whether the idiosyncratic distribution of transduction mechanisms fo

105 ing aminoglycoside antibiotic exposure in an idiosyncratic dose-independent manner.

106 Idiosyncratic drug induced liver injury (DILI) remains p

107 anous nephropathy should be recognized as an idiosyncratic drug reaction to many NSAIDS.

108 er causes of FHF (11 paracetamol overdose, 2 idiosyncratic drug reaction, 3 Wilson's disease) were av

109 that reactive metabolites may be involved in idiosyncratic drug reactions.

110 in vivo, which may result in immune-mediated idiosyncratic drug toxicity (IDT).

111 Idiosyncratic drug toxicity, defined as toxicity that is

112 Mechanistic study of idiosyncratic drug-induced hepatitis (DIH) continues to

113 Idiosyncratic drug-induced liver injury (DILI) is a rare

114 Idiosyncratic drug-induced liver injury (DILI) is a rare

115 Idiosyncratic drug-induced liver injury (DILI) is a rare

116 Idiosyncratic drug-induced liver injury (DILI) is among

117 Idiosyncratic drug-induced liver injury (DILI) is an imp

118 Idiosyncratic drug-induced liver injury (DILI) is tradit

119 o gather new and important data published on idiosyncratic drug-induced liver injury (DILI) over the

120 ses of a multiethnic cohort of patients with idiosyncratic drug-induced liver injury (DILI) to identi

121 The mechanism of idiosyncratic drug-induced liver injury (IDILI) remains

122 evidence suggests that many cases of serious idiosyncratic drug-induced liver injury are mediated by

123 patotoxicity (29%), indeterminate ALF (23%), idiosyncratic drug-induced liver injury DILI (22%), acut

124 However, the complexity of idiosyncratic drug-induced liver injury means that no cu

125 oaches to study these reactions, focusing on idiosyncratic drug-induced liver injury.

126 receiving a drug whose proarrhythmia may be idiosyncratic (e.g., quinidine), and for patients who ar

127 yloid burden effect in transthyretin, but an idiosyncratic effect in light chain amyloidosis.

128 afe, suggesting a mechanism for its observed idiosyncratic effect.

129 l outputs can provide insight into seemingly idiosyncratic effects of neuromodulators across individu

130 ural properties of hydrogen bonds within the idiosyncratic environment of an enzyme active site and p

131 The idiosyncratic epistasis theory explains the universaliti

132 ver, this task is often difficult, slow, and idiosyncratic, especially when the sequences are highly

133 This idiosyncratic eukaryotic rRNA evolution is not observed

134 sites, successional trajectories were highly idiosyncratic, even when controlling for prior land use,

135 so evidence for the significant influence of idiosyncratic experience as the environmental component

136 phage subset and DC lineage markers each had idiosyncratic expression profiles.

137 s' face-sensitive neural responses and their idiosyncratic eye-movement patterns during identity proc

138 her these individual differences concur with idiosyncratic face-sensitive neural responses remains un

139 eotide relative abundances are considered an idiosyncratic feature of genomes, regarded as a 'genomic

140 tic site to enhance pre-transfer editing, an idiosyncratic feature of IleRS, remains elusive.

141 An idiosyncratic feature of RARS/RARS-T is the presence of

142 olecule technique, to demonstrate common and idiosyncratic features in the DNA strand exchange mechan

143 fic analytic techniques revealed a number of idiosyncratic features of post-concussion symptomatology

144 small 'minicircle' elements, and a number of idiosyncratic features of RNA metabolism including trans

145 tures of the produced utterance itself or on idiosyncratic features of the addressee or communicative

146 recent discovery of Fluc channels, numerous idiosyncratic features of these proteins have been unear

147 Most of the variation appears to result from idiosyncratic features that derive from local sequence c

148 ng lineages possessing both reproducible and idiosyncratic features.

149 n that is shared across brains is encoded in idiosyncratic fine-scale functional topographies.

150 gaging in face recognition, observers deploy idiosyncratic fixation patterns to sample facial informa

151 processing, the cellular consequences of the idiosyncratic FKRP mutations have not been determined.

152 The robust preference for idiosyncratic flight paths, and the tendency to pass obs

153 Individual birds displayed highly idiosyncratic flight trajectories that were consistent f

154 ion electron microscopy (TEM) is notoriously idiosyncratic for particular species or specimen types.

155 ividual populations; however, the trends are idiosyncratic; for example, the frequency of collateral

156 tton presses with trivial motor demands, the idiosyncratic forces biasing sequences of action choices

157 the parietal reach region use nonuniform and idiosyncratic frames of reference.

158 flanked by subfamily-specific extensions of idiosyncratic function.

159 pment of assessment methodology to cater for idiosyncratic functions and low-rate behaviours.

160 Basilar dendrites exhibited idiosyncratic geometry across and within taxonomic group

161 used antiretroviral drug, is associated with idiosyncratic hepatotoxicity and dyslipidemia.

162 in the HLA region have been associated with idiosyncratic hepatotoxicity attributed to flucloxacilli

163 This reaction resembles RAN idiosyncratic hepatotoxicity in humans.

164 g and is among the most common drugs causing idiosyncratic hepatotoxicity in several recent series wi

165 Although the mechanism of BBR-induced idiosyncratic hepatotoxicity remains unelucidated, cytoc

166 n changes and their usefulness in predicting idiosyncratic hepatotoxicity.

167 convergence could have been contingent on an idiosyncratic history that is not expected to repeat.

168 k neutrality emerges if reproductive risk is idiosyncratic (i.e., uncorrelated across each given gene

169 a TMA, either dose-dependent toxicity, or an idiosyncratic immune-mediated reaction due to drug-depen

170 Networks were highly idiosyncratic in nature, yet emotional symptoms (nervous

171 hich connectivity in cerebellar networks is "idiosyncratic" in an individual with autism.

172 Whereas most cortical laminae exhibited idiosyncratic increases in zinc histochemical staining w

173 ded alkyl-aryl side chain, which establishes idiosyncratic interactions with the ribosomal RNA.

174 the ancestral introns and some of the older idiosyncratic introns have been lost at least 48 times i

175 stories (embryo fat and fecundity) exhibited idiosyncratic, island-specific responses.

176 This variation resulted from idiosyncratic joint effects of assembly sequence, produc

177 ly in ants, thelytoky underlies a variety of idiosyncratic life histories with unique evolutionary an

178 ne of the most common causes of drug-induced idiosyncratic liver injury and liver failure.

179 onvincingly documented, clinically apparent, idiosyncratic liver injury.

180 s an uncommon but potentially fatal cause of idiosyncratic liver injury.

181 arket in March 2000 because it caused severe idiosyncratic liver injury.

182 understanding of the mechanisms that lead to idiosyncratic liver toxicity would be extremely benefici

183 ss benefits from multiple mating and species-idiosyncratic logistical limits on polygamy.

184 to cause severe hepatocellular injury in an idiosyncratic manner, routine liver chemistries should b

185 duplexes closed with wobble base pairs in an idiosyncratic manner.

186 finches reveals the potential advantages of idiosyncratic mate choice in monogamous animal species.

187 ydrolysis of a misactivated amino acid by an idiosyncratic mechanism, the aptamer is shown here to in

188 ugh shared, supramodal mechanisms or through idiosyncratic, modality-specific mechanisms.

189 o dissimilar models of the disease to detect idiosyncratic, model-specific events.

190 tical implications and utility of developing idiosyncratic models of visual perception.

191 behaviors by means of their broad tuning to idiosyncratic, multijoint actions.

192 Moreover, idiosyncratic mutations appear to be as functionally con

193 most common significant toxicity, but fatal idiosyncratic myelosuppression (grade V) was observed in

194 The regions required for splicing include an idiosyncratic N-terminal extension, the nucleotide-bindi

195 Here, we show that the idiosyncratic N-terminal region is in fact comprised of

196 bout the conceptual basis for allostery, the idiosyncratic nature of allosteric mechanisms resists ge

197 e, their production has been hampered by the idiosyncratic needs of the encoding DNA tag relegating D

198 interindividual differences are mirrored by idiosyncratic neural responses remains unknown.

199 ibit idiosyncratic olfactory preferences and idiosyncratic neural responses to odors, and that behavi

200 Given that each nucleus has idiosyncratic neuroanatomical connections and prevailing

201 ls (aOPCs), transformed from fetal OPCs, are idiosyncratic neuroglia of the central nervous system (C

202 wever, their growth trajectories become more idiosyncratic; nonlinear effects, sediment supply, wind

203 om a highly inbred laboratory strain exhibit idiosyncratic odor preferences that persist for days.

204 onstrates that individual Drosophila exhibit idiosyncratic olfactory preferences and idiosyncratic ne

205 finer scales the empirical trees are highly idiosyncratic, on coarse scales the backbone of these tr

206 the nursing roles and services studied were idiosyncratic, opportunistic and reactive, rather than p

207 Apparently idiosyncratic or difficult to predict effects of tempera

208 levels, we found that productivity is either idiosyncratic or increases with respect to species richn

209 icted compared to adverse events that may be idiosyncratic or related to secondary target effects tha

210 rental plants and our observation that these idiosyncratic organisms segregate tetraploid offspring w

211 Variations in nodal yield are due to idiosyncratic patient and tumor characteristics and diff

212 responses is consistent with a positive but idiosyncratic pattern of ecosystem function with increas

213 e we connect these two facts by showing that idiosyncratic patterns of brain activation are associate

214 poral pole, and this unique code can predict idiosyncratic patterns of memory errors.

215 to auditory events (N1-P2) [3], triggered by idiosyncratic perceptual features acquired through learn

216 We find support for idiosyncratic phylogeographic patterns between these was

217 by the elevation dependent filtering in the idiosyncratic pinna cavities.

218 the identification and repair of recoding at idiosyncratic positions in the genome.

219 ss (e.g., jump-jumped) with an unpredictable idiosyncratic process typified by the irregulars (e.g.,

220 c experiences from the past requires storing idiosyncratic properties that define particular moments

221 l culture lines to reflect their complex and idiosyncratic protein profiles, resulting in up to 40% o

222 ctively, our findings favor the existence of idiosyncratic, rather than universal face representation

223 he effective processing of identity involves idiosyncratic, rather than universal face representation

224 refractive index as a result of allergic or idiosyncratic reaction of the ciliary body.

225 than combine when the first AED produces an idiosyncratic reaction, is poorly tolerated at a low/mod

226 ng aspects of drug-drug interactions are the idiosyncratic reactions that are unpredictable and quite

227 but the resulting species composition can be idiosyncratic, reflecting species' true biomass abundanc

228 The interaction with conserved as well as idiosyncratic regions explains how maturases in some org

229 ysical space; rather, perceived space has an idiosyncratic relationship with the real world.

230 suggesting that this cell type has a large, idiosyncratic repertoire of expressed genes.

231 late are individually unique and where those idiosyncratic representations are encoded in the brain a

232 d that spatial encodings that use a range of idiosyncratic representations may increase computational

233 of human fMRI data to measure the common and idiosyncratic representations of famous face morphs duri

234 hat the analyses are no longer confounded by idiosyncratic responders and thus improves the reliabili

235 fluctuations (the last 250,000 y) but detect idiosyncratic responses across species and uniformity of

236 texture identity is reliably encoded in the idiosyncratic responses of populations of cortical neuro

237 Despite seemingly idiosyncratic responses of species to global change, gre

238 lucidate mechanisms underlying concordant or idiosyncratic responses of vertebrate species evolving i

239 Given these idiosyncratic responses to climate warming, and their va

240 ct locally adapted populations that may show idiosyncratic responses to environmental and anthropogen

241 ding a general pattern, our results revealed idiosyncratic responses to historical and ecological pro

242 s driven entirely by five ASD subjects whose idiosyncratic responses were also internally unreliable.

243 ody datasets display limited convergence and idiosyncratic responses.

244 a robust gene set that is less sensitive to idiosyncratic results and for quantifying study characte

245 be a hidden generality among these seemingly idiosyncratic results: speciation and extinction rates f

246 o factors arising from their drug pipelines (idiosyncratic risk), but also from general economic cond

247 ct of credit on productivity, the sharing of idiosyncratic risks, and the economic influence of envir

248 Insertions and additions of idiosyncratic RNA binding elements that facilitate docki

249 eral individual QTLs also have a significant idiosyncratic role.

250 of their poorly constrained soft anatomy and idiosyncratic scleritome, which comprises an operculum,

251 hared belief system and, in contrast, how an idiosyncratic set of arbitrarily linked beliefs held by

252 Thus, systematic and idiosyncratic signals may coexist within individual neur

253 dgments of briefly presented targets produce idiosyncratic signatures of perceptual distortions in ea

254 ) reduced occupancy, range contractions, and idiosyncratic species redistributions; (b) degradation o

255 s of different bacterial species may lead to idiosyncratic, species-specific interactions of the drug

256 the RTs produced by ensembles of redundant, idiosyncratic stochastic accumulators under various term

257 abolism to the host, they have also acquired idiosyncratic strategies to exploit host nutritional sup

258 ty binding site in intron subdomain DIVa, an idiosyncratic structure at the beginning of its own codi

259 ty binding site in intron subdomain DIVa, an idiosyncratic structure at the beginning of the LtrA cod

260 the beginning of its own coding region in an idiosyncratic structure, DIVa.

261 Idiosyncratic susceptibility to infections and malignanc

262 n other body systems, cognitive reserve, and idiosyncratic susceptibility.

263 f apparent sub-domains may sometimes reflect idiosyncratic tasks rather than meaningful dissociations

264 Idiosyncratic tendency to choose one alternative over ot

265 ions of a drug's known therapeutic effect or idiosyncratic.This review presents the evidence for a ge

266 in Tabby, but each requires its action at an idiosyncratic time of development: by E17 for guard, by

267 lthough these transitions typically occur at idiosyncratic times across people, participants exhibite

268 In contrast, reactivation of neural patterns idiosyncratic to a given AB trial measured with PSA only

269 ead to conclusions from experiments that are idiosyncratic to a particular environment.

270 vents in the same category, but not features idiosyncratic to a particular event, are important in re

271 nt study indicate that reactivating features idiosyncratic to a particular experience during interfer

272 zation, raising the concern that results are idiosyncratic to a particular laboratory.

273 cterizing mutants may yield results that are idiosyncratic to a particular laboratory.

274 tive domains or modality-specific mechanisms idiosyncratic to each domain.

275 with places (in the acceptor stem) that are idiosyncratic to each synthetase-tRNA pair.

276 es, indicating that these components are not idiosyncratic to invertebrates.

277 nality to the mechanisms, some positions are idiosyncratic to LeuRS or IleRS.

278 Here we report that looping is not idiosyncratic to long genes but occurs between the dista

279 found (1) developmental patterns, which were idiosyncratic to the anatomical area examined, and (2) a

280 erlying, stable network architecture that is idiosyncratic to the individual and persists across task

281 end on highly differentiated motifs that are idiosyncratic to the mammalian system.

282 as spinal cord, indicating that they are not idiosyncratic to the particular cell line used or a "cul

283 However, idiosyncratic toxicities are usually not observed until

284 We describe some of the idiosyncratic toxicities of this agent, some of the mech

285 Idiosyncratic toxicity can occur when a convergence of r

286 to understand the mechanisms underlying the idiosyncratic toxicity induced by trovafloxacin.

287 Because some single axons could follow idiosyncratic trajectories to the target glomerulus, it

288 ors have not been reported and imprinting is idiosyncratic, tumor-specific changes in wild-type p73 e

289 , like those of so many others, had too many idiosyncratic twists and turns that had to work out just

290 presentations in prefrontal cortex predicted idiosyncratic variability in attentional performance whe

291 pattern in right LPFC successfully predicted idiosyncratic variability in search performance, such th

292 e to efficiently screen a candidate gene for idiosyncratic variants in thousands of samples.

293 iduals allow disentangling age patterns from idiosyncratic variation and analyzing how age patterns c

294 representations, whilst nonetheless sharing idiosyncratic variations in spatial topology.

295 Here we observe similar idiosyncratic variations with strong interparticipant co

296 nt studies have consistently reported robust idiosyncratic visual sampling strategies during face rec

297 ules, each paired with separate theories and idiosyncratic vocabularies.

298 an subject skilfully produced "wookies" - an idiosyncratic vocalization exhibiting a unique spectral

299 The surgeon's benefits are idiosyncratic with "responders" experiencing marked impr

300 We found that evolvability was idiosyncratic with respect to initial genotype; that is,