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1                                              If so, ACVP should be a cytotoxic agent if properly deli
2                                              If so, and in the absence of data to show that risk in v
3                                              If so, anti-microglial agents targeting the pro-inflamma
4                                              If so, are these "stoichiometries" preserved over time?
5 ther a metabolic adaptation to OF exists and if so, attenuates weight gain.
6                                              If so, available evidence predicts that such stripes sho
7                                              If so, because synaptic strength and size are correlated
8                                              If so, biodiversity conservation at the appropriate scal
9                                              If so, both neurodegeneration and cancer may be diseases
10  sea level rise is currently increasing and, if so, by how much.
11  channel mRNAs are actively maintained, and, if so, by what form of feedback.
12 ty acid oxidation influences ER function or, if so, by what mechanism.
13 modifying benefits in an AD mouse model and, if so, by what molecular mechanisms.
14  neuronal populations act as pacemakers, and if so, by which signalling mechanisms, and finally the n
15                                              If so, can silent electrical synapses be activated to be
16                                              If so, carbon costs of fungal symbionts could indirectly
17                                              If so, changes in the experienced strength of gravity sh
18                                              If so, colony function might fruitfully be studied using
19                                              If so, complexity could provide an advantage counteracti
20                                              If so, could the enhanced aggregation rate of Abeta42 co
21                                              If so, decisions under variable action costs could take
22 r N1 could modulate microglial function and, if so, determine the consequences for the surrounding ti
23 r the BBB is disrupted in Ppt1-KO mice, (ii) if so, do T(H)17-lymphocytes underlie this complication,
24                                          (2) If so, do these definitively improve outcomes?
25 L chains exists in the human repertoire, and if so, do they edit H chains with anti-DNA signatures?
26 t inactivation produce similar deficits and, if so, do they recover?
27 her DUSP1 expression is regulated by SAM and if so, elucidate the molecular mechanisms.
28 measure this observed strain-dependency, and if so, establish parameters for empowering phenotype- an
29 ariants) were more likely to carry URFs and, if so, examined whether they progressed more rapidly tha
30 ns, and adults (nonsmokers and smokers) and, if so, factors influencing the decline(s).
31                                              If so, host organisms may use the local oxygen level to
32 as, are there defined DCV docking sites and, if so, how are DCVs delivered to these release sites?
33                                              If so, how can neuroscientists use deep networks to mode
34                                              If so, how did we get them in the first place, and when
35                                          And if so, how do its properties relate to the rapid adaptat
36 l-complex code directing movement exist, and if so, how does it effect changes in the control of limb
37 ionable assessment of hospital quality, and, if so, how hospitals might improve their performance.
38                                          And if so, how is this accomplished by the medial temporal l
39 ject to significant developmental death, and if so, how it occurs.
40  to whether to correct for multiplicity and, if so, how it should be done.
41 physician noted any suspicious lesions, and, if so, how lesions were managed.
42 on with the DTC PGT experience; whether and, if so, how many results could be used to improve health;
43 anisms of target mRNA decay also exist, and, if so, how much they contribute to miRNA-induced mRNA de
44 ed whether they would be willing to pay, and if so, how much.
45              It remains unclear whether and, if so, how nonhuman animals make on-the-fly predictions
46          However, it is unclear whether and, if so, how people actually condition their punishment of
47 ntial to produce endogenous AHR ligands and, if so, how production of these ligands is controlled.
48 inate yeast strains based on odor alone, and if so, how such resolution is achieved by the olfactory
49 n primate OFC signal social information and, if so, how such signals compare with responses to primar
50 variation between the different isolates and if so, how the divergent structures can support similar
51 to what is seen in differentiated cells, and if so, how these altered properties specifically impact
52 ations of funds led by people of color, and, if so, how these biases manifest.
53  are also dependent on CSF1R signalling, and if so, how these cells contribute to disease pathogenesi
54 t role in the chaperoning of syntaxin-1 and, if so, how these dual functions of domain-3a are regulat
55 not known if the two systems interplay, and, if so, how they do.
56 whether such Vbeta rearrangements occur and, if so, how they might be regulated, we analyzed mice wit
57 whether such strategies are appropriate and, if so, how they should be most effectively implemented.
58  was predictive of future reading skill and, if so, how this brain-behavior correlation informs devel
59  including whether SRs compete for Cul1 and, if so, how this competition is managed.
60 atelet reactivity by sequestering RGS18 and, if so, how this is accomplished.
61 ptured FH becomes functionally enhanced and, if so, how this is achieved at a structural level.
62 of CSR as it is for V(D)J recombination and, if so, how this is achieved is unknown.
63 tually initiate colorectal cancer (CRC), and if so, how this might occur.
64 r actin binding reverses this transition and if so, how this reversal is coordinated with actin-activ
65 he lack of clear guidance about whether and, if so, how to return ES/WGS incidental results limits th
66                                 Whether, and if so, how various isoforms play distinct roles in norma
67  ligand are actually promoting relapse, and, if so, how we can use this information to adjust our the
68 lymers interact with the mucus hydrogel, and if so, how, remains unclear.
69 omosome segregation fidelity in cancers and, if so, how.
70 regulates heterochromatin in Neurospora, and if so, how.
71 n whether Al actually causes DNA damage and, if so, how.
72 ents could be used to produce analgesia, and if so, how.
73 s or longer, but do they sleep in flight and if so, how?
74 ent impact the underlying gene circuits and, if so, how?
75  host, a process we term immunosensing, and, if so, how?
76 mmunities respond to habitat conversion and, if so, how?
77 h assemblage on the West African margin and, if so, identify potential cues for the behaviour.
78 n occurs after sorafenib therapy in HCC, and if so, if it impacts the therapeutic efficacy.
79  online as behavioral preferences change and if so, if it is causally linked to specific components o
80 rect interaction between m152 and RAE-1 and, if so, if m152 interacts differentially with the five id
81 ticles (Ag NPs) elicit this same effect and, if so, if the NP itself and/or the dissociation of ionic
82 AM (neuron-glia cell adhesion molecule) and, if so, in what compartment it is required.
83               Do they improve movement, and, if so, in what way?
84 nctions of these excitatory projections, and if so, in which projection pathways.
85                                              If so, inhibition of CGRP receptors may be a clinically
86                                              If so, inhibition of tetherin activity by Vpu may balanc
87                                              If so, input from subduction zones into the overlying pl
88                                              If so, is it in extrinsic (world-centered) or intrinsic
89                                              If so, is it possible that just as there are edifices th
90                                              If so, is there any contribution of these extinct popula
91                                              If so, it constrains the WAIS contribution to global sea
92                                              If so, it is important to understand whether successful
93  crust production over the age of the Earth; if so, it is now either a primitive refugium at the core
94                                              If so, it would constrain theories of how movement to mu
95                                              If so, it would have important implications for our unde
96                                              If so, it would require considerable forethought.
97 rated in peripheral sympathetic ganglia and, if so, its effect on synaptic transmission.
98 determined whether IPC is present in WM and, if so, its mechanism.
99                                              If so, its signature might be present in how the motor s
100 dictate whether an organelle assembles, and, if so, its size, providing a mechanistic link between or
101 ents are in risk of oesophageal perforation, if so, management may be conservative but mediastinal dr
102 gnal that migrates from underlying brain and if so, may implicate newly discovered bridging vessels t
103                                              If so, mitigating CH4 emissions must be balanced with th
104                                              If so, monitoring donor endothelium after DMEK or other
105                                              If so, neurons that are part of coherent ensembles may p
106 ther exploration of mechanistic linkage and, if so, novel therapeutic strategies such as demethylatin
107 e binding of biochemical signals occurs, and if so, on time scales relevant to microbial growth and c
108                                              If so, other aberrant positive-feedback networks might d
109                                              If so, participant behaviour on a high-level decision-ma
110                                              If so, RanBP9 provides a great opportunity to develop no
111 treated in a hospital that conducts ECT and, if so, received the procedure.
112 croscopic local field potentials (LFPs), and if so, respiratory (r) LFPs could be used to map the fun
113                                              If so, second-order statistics could themselves carry in
114                                              If so, should results of a platelet function test be use
115                                              If so, societies without electricity may sleep longer.
116                                              If so, such covariance could be used to predict contacts
117 plex phenotypes in multi-cellular organisms; if so, such rewiring may leave traceable changes in the
118                                              If so, targeting extracellular tau species may slow the
119                                              If so, the American West, the Middle East, and southern
120                                              If so, the cell origin of leukemia-initiating stem cells
121                                              If so, the explanation could be that storing rapidly flu
122                                              If so, the genomic distribution of RNA editing site loss
123                                              If so, the high levels of membrane CL found in alkaliphi
124 inst new-onset depression and anxiety and 2) if so, the intensity and amount of exercise required to
125                                              If so, the loss of consciousness, a feature of sleep, wo
126                                              If so, the male bias in mutation should be substantially
127  to coordinate their emerging functions and, if so, the mechanisms underlying this process.
128 sion involves a discrete tethering step and, if so, the potential role of GTP hydrolysis and cross-ov
129                                              If so, the presence of these T cells could alter the int
130 t estrogen is combined with progesterone and if so, the type of progesterone used, as well as the rou
131 perature-sensitive phenotype can revert and, if so, the types of substitutions that will emerge (i.e.
132 y role in intestinal I/R-induced injury and, if so, the underlying mechanisms, remain unknown.
133                                              If so, the vasodilating effects of nitrite would be atte
134 Statistics on whether patients had died and, if so, their cause of death were available for 7,016 of
135                                              If so, then a failure to manage for hybridization will e
136 whether females have a toxic humoral factor; if so, then its strength was compared with that of males
137                                              If so, then Life History Theory offers a way to reconcil
138                                              If so, then membrane proteins stabilized by this feature
139                                              If so, then phasic response of dopamine neurons to cues
140                                              If so, then priming offers no special insight into gramm
141                                              If so, then strategic processes would need only up-regul
142  to analyzing temporal properties of sounds; if so, then there should be systematic depth-dependent c
143                                          (c) If so, then why do they let it happens?
144                                              If so, there may be equipoise to test if VT less than or
145                                              If so, there must be additional sRNAs from mRNAs that ac
146 e asked if they were aware of their VF loss; if so, there were encouraged to describe it in their own
147                                              If so, these may be the preferred surgery for women of r
148                                              If so, they should react in a similar manner to top-down
149                                              If so, this is preceded by a region of bistability.
150                                              If so, this process could be distinct from human hematop
151                                              If so, this technique may have the potential to double t
152                                              If so, this type of collision will greatly affect molecu
153                                              If so, this widely used analgesic may potentiate the adv
154                                              If so, this would provide new insight into the functiona
155                                              If so, this would represent a fundamental feature of gen
156 ha stimulates insulin synthesis in vivo and, if so, through which mechanism(s) remain largely unknown
157 srupt the intentional control of memory and, if so, through which neural mechanism.
158 ding of the mouse and rat hair follicle and, if so, to assess its similarity to that of the rat muscl
159 at model of pulmonary hypertension (PH) and, if so, to define the underlying mechanisms.
160 sure by itself is an etiological factor and, if so, to determine the overall nature of cognitive defi
161 basal state in insulin-resistant muscle, and if so, to determine whether the effects were associated
162 ring goal-directed behaviors for sucrose and if so, to determine whether the two are causally linked.
163 prevents obesity-induced cardiomyopathy, and if so, to elucidate the underlying mechanisms.
164 eine underlies the observed association and, if so, to evaluate its mechanisms of action.
165 xpression and placental vascularization and, if so, to evaluate the effectiveness of the selective PP
166 h early forms of Alzheimer disease (AD), and if so, to examine the extent and pattern of leakage.
167 rly life can shape senescence schedules, and if so, to examine whether variation among individuals or
168 stomatitis virus (rVSV) vaccine vectors, and if so, to identify strategies by which IL-1beta mediated
169  during the exponential phase of growth and, if so, to identify the binding sites.
170 olytically released from cell membranes and, if so, to identify the responsible sheddase and determin
171 s with clinical response to bortezomib, and, if so, to optimize this oncolytic strategy.
172 k and urine produced by lactating women and, if so, to quantify typical consumption by breastfed infa
173 ed with older adults with normal vision and, if so, to understand why.
174 ls from the meninges to the spinal cord, and if so, to what extent and through which classes of perip
175 is expressed in insulin-producing cells and, if so, to what extent it affects beta cell function.
176 suicide attempt rates to assess whether, and if so, to what extent, the well-established relationship
177 nhibition may be genetically determined, and if so, transplant recipients should receive personalized
178                                              If so, two key properties determine its selectivity and
179                                              If so, under what conditions?
180                                              If so, unlike all other lignin pathway manipulations tha
181                                              If so, vaccinated individuals should reciprocate by bein
182                                              If so, vaccines able to induce durable RSV-specific IgA
183                                              If so, volume loading of heat-stressed individuals would
184 ng more often degenerated into re-entry and, if so, was more likely to be sustained for more cycles.
185                                              If so, was that change for the better, worse, both or ne
186                                              If so, we predicted that selective inactivation of this
187                                              If so, what (if any) characteristic properties might suc
188                                              If so, what are the effects on quality of mental and phy
189 other highly chlorinated phenols (HCPs); and if so, what are the major physicochemical factors in det
190 cidal behaviors coaggregate in families and, if so, what are the mechanisms underlying this coaggrega
191                                          And if so, what are the neural mechanisms that support such
192 e in a high sucrose fed animal model and (b) if so, what could be the molecular mechanism.
193 istinctly different motifs on chromatin, and if so, what determines the usage of specific motifs.
194 er these networks functionally interact and, if so, what factors mediate such interactions.
195 icient synapses actually occurs in vivo, and if so, what factors regulate it and what role it might p
196 103+ DC even exist in the ocular mucosa, and if so, what functions they have in shaping immune respon
197                                              If so, what is arguably the greatest ever revolution in
198 ocular surface of normal living rabbits, and if so, what is its efficacy and tolerability versus cycl
199  technology over other novel approaches, and if so, what is the flip side to the use of this technolo
200 egrins outside FAs can transmit tension, and if so, what is the tension range.
201 er there exists a genetic basis of CCCA and, if so, what it is.
202  is not known whether ATF6 is activated, and if so, what its function is during hypertrophic growth o
203 unclear whether BBB is disrupted in INCL and if so, what might be the molecular mechanism(s) of this
204  we asked if they themselves aggregated and, if so, what parameters regulated their aggregation.
205 of its neurons is capable of exhibiting, and if so, what principles define this constraint.
206  T cells are functionally heterogeneous and, if so, what signals specify the differentiation of MP ce
207 it has a role within sympathetic neurons and if so, what target genes it regulates to facilitate targ
208 from the same joint should be performed and, if so, what testing should be undertaken.
209 stinct and specialized neural machinery, and if so, what that machinery's organization might be.
210 lved in response to selective pressure--and, if so, what that pressure might have been--or whether th
211 n directly cause this phenotypic change and, if so, what the signaling mechanism is, were explored in
212  size as part of a regenerative program and, if so, what the underlying mechanism is have remained la
213 s could be effective in axonal blockage and, if so, what the underlying mechanisms are.
214 ther microRNAs regulated EPC senescence and, if so, what the underlying mechanisms are.
215 similar transients occurred in the past and, if so, what their forcing processes were.
216 are present in a diverse set of viruses and, if so, what they may imply about viral biology.
217 ar ataxia type 1, forms toxic oligomers and, if so, what underlies their toxicity.
218 rsibly retain a model nanoparticle, ZnO, and if so, what would be the difference between bound ZnO NP
219 e and TrkB activation occur during sLTP, and if so, when and where.
220                                              If so, when did consciousness evolve?
221                                              If so, when representing others' current mental state, t
222 ed in the management of skin abscesses, and, if so, when, is controversial.
223       Is the metal positioning specific, and if so, where is which ion located?
224 share this preference for fair partners and, if so, whether a prospective partner's past fair behavio
225 e contains anergic autoreactive B cells, and if so, whether antigen was encountered during or after t
226 referentially myelinated by glial cells, and if so, whether axo-glial synapses are involved, are long
227 HC contacts promote TCR-MHC specificity and, if so, whether differences exist in TCR V gene compatibi
228 s responses to bacteria in the airspace and, if so, whether differently from its effects in other tis
229 rmine whether an early impairment exists and if so, whether fronto-striatal circuits were associated
230 fers from that found in diseased tissue and, if so, whether glycosylation affects inhibitor binding.
231 ignaling is functional in P2X-dblKO mice and if so, whether it activates the primary viscerosensory n
232 vity can be detected in oral fluid (OF) and, if so, whether it correlates with SCRA concentrations.
233  if an airway microbiome exists at birth and if so, whether it is associated with subsequent lung dis
234 the in the spinal cord gray matter (GM), and if so, whether it is because of an aberrant increase in
235 nduces IFN-beta from myeloid phagocytes, and if so, whether it is helpful or harmful to the host to d
236 DTic human cardiac effect indeed exists, and if so, whether it is specific to JDTic or represents a K
237  dorsal and ventral progenitor lineages and, if so, whether it regulates common or unique networks of
238 SDB) is different from healthy children and, if so, whether it resolves with treatment, we used heart
239 ating exercise-induced cardioprotection, and if so, whether its activation independent of exercise ca
240  bone abnormalities associated with MDD and, if so, whether ketamine treatment corrected the abnormal
241 nterregulatory response to hypoglycemia, and if so, whether knockdown of in the VMH can improve count
242 r RB1 mutation drives tumor progression and, if so, whether loss of pRb/E2f interaction is responsibl
243 ediated by the ABCG5/G8 complex in vivo, and if so, whether LXRa is involved.
244 th sites can be simultaneously occupied, and if so, whether monobodies bind independently or cooperat
245 educing death and disability at 90 days, and if so, whether oxygen given at night only, when hypoxia
246 ET is able to detect additional disease and, if so, whether patient management is altered.
247 r these beneficial and harmful effects, and, if so, whether PDE3 can be targeted so as to increase co
248 y rings affect AML strains in patients, and, if so, whether ring-induced perturbations in leaflet str
249 onal (i.e., intracellular) consequences and, if so, whether such consequences are associated with inc
250 ytic function of the proteasome in mice and, if so, whether the enhancement can rescue a bona fide pr
251 (CT Topo I) on a native supercoiled DNA and, if so, whether the enzyme catalyzes its subsequent equil
252 with sigma(70) R4 at class II promoters and, if so, whether the interactions occlude the binding of s
253 n an isolated monolayer of copper oxide, and if so, whether the two-dimensional superconductivity and
254 re generic to the REFeAsO-type materials and if so, whether their exact topology is responsible for t
255 resented among myocardial sphingolipids and, if so, whether their function and metabolic routes were
256 hether humans eating eggs generate TMAO and, if so, whether there is an associated increase in a mark
257  ligand to activate VMH EphA5 receptors, and if so, whether these changes could contribute to pathoge
258 Fs are assembled into similar complexes and, if so, whether these complexes are unique to SLFs.
259  network can have preferred frequencies and, if so, whether these frequencies are the same or correla
260 ents express functional 5-HT3 receptors and, if so, whether these receptors play a role in transmissi
261 tations may be a cortex-wide phenomenon and, if so, whether these representations can be organized in
262  very different class of drug (ethanol), and if so, whether these systems might be involved in their
263 anglion cells (DSGCs) exist in primates and, if so, whether they are the equivalent to mouse and rabb
264  normal and diseased parathyroid glands, and if so, whether they had any functional effects on parath
265 alogous approach-avoidance dispositions and, if so, whether they share a homologous neurobiological s
266  cortex compare durations and distances and, if so, whether they use similar mechanisms.
267 ents, could be observed during encoding and, if so, whether they would predict different levels of ac
268 s in neurons leads to cell-cell fusion, and, if so, whether this affects neuronal fate, function, and
269 targets change during tumor progression and, if so, whether this affects precision medicine trial des
270 adverse metabolic profiles in offspring, and if so, whether this association is causal, via intrauter
271 agged adult cardiac tissue progenitors, and, if so, whether this cell-based signal could serve as a q
272 mation needed to restore these patterns-and, if so, whether this could improve tissue function-is not
273  increase hepatic inflammatory signaling and if so, whether this effect 1) involves activation of Kup
274 rinking cessation phase (first 6 weeks), and if so, whether this effect persisted.
275 r readmission rates than white patients, and if so, whether this effect was mediated by the hospitals
276 iac arrest has significantly increased, and, if so, whether this is attributable to AED use.
277 les during genomic surveillance in vivo and, if so, whether this is done via direct or indirect means
278 whether climate variability is changing, and if so, whether this is due to anthropogenic forcing, are
279 d with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or sh
280 dark toward haptically explored objects (and if so, whether this reactivation might be due to imagery
281 nimals are placed in a cold environment and, if so, whether this response is required for the associa
282 trophin modulated the expansion of OPCs and, if so, whether this was effected through the serial enga
283 ine whether the patient was followed up and, if so, whether treatment was initiated and/or symptoms w
284 e coagulation activation in heat stroke and, if so, whether upstream inhibition of coagulation activa
285  improves lipid metabolism in the liver and, if so, whether VASP's effects are mediated by AMPK.
286 essels associated with brain metastases, and if so, whether VCAM-1-targeted MRI enables early detecti
287 whether CTL inactivation is Ag specific and, if so, which APCs are involved.
288 t of stress on brain gray matter volume and, if so, which brain regions mediate the effect of this ge
289 n support memory-guided decision making and, if so, which brain regions play a role in compensation.
290 n significantly improve detection power, and if so, which covariates are more relevant for EWAS data.
291 oxidation and esterification in the MBH and, if so, which hypothalamic cell type(s) and intracellular
292 determine if an enhancement is indicated and if so, which method will be the safest and most efficaci
293 n individual mental process or disorder and, if so, which molecules confer such specificity.
294 g as a marker of recent neural activity and, if so, which of its many gene targets underlie circuit r
295 ther OXTR is truly associated with ASD, and, if so, which OXTR single-nucleotide polymorphisms (SNPs)
296 x vaccination is driving the phenomenon, and if so, why is re-emergence not universal throughout the
297 iddle-income, and low-income countries, and, if so, why these differences exist.
298 oughts occurred in the southwestern US, and, if so, with what regularity and intensity.
299 ny of the subunits in the septin collar and, if so, with which ones.
300 xplain the emergence of drug resistance, and if so, would have prognostic and predictive utility.

 
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