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14 neuronal populations act as pacemakers, and if so, by which signalling mechanisms, and finally the n
22 r N1 could modulate microglial function and, if so, determine the consequences for the surrounding ti
23 r the BBB is disrupted in Ppt1-KO mice, (ii) if so, do T(H)17-lymphocytes underlie this complication,
25 L chains exists in the human repertoire, and if so, do they edit H chains with anti-DNA signatures?
28 measure this observed strain-dependency, and if so, establish parameters for empowering phenotype- an
29 ariants) were more likely to carry URFs and, if so, examined whether they progressed more rapidly tha
32 as, are there defined DCV docking sites and, if so, how are DCVs delivered to these release sites?
36 l-complex code directing movement exist, and if so, how does it effect changes in the control of limb
37 ionable assessment of hospital quality, and, if so, how hospitals might improve their performance.
42 on with the DTC PGT experience; whether and, if so, how many results could be used to improve health;
43 anisms of target mRNA decay also exist, and, if so, how much they contribute to miRNA-induced mRNA de
47 ntial to produce endogenous AHR ligands and, if so, how production of these ligands is controlled.
48 inate yeast strains based on odor alone, and if so, how such resolution is achieved by the olfactory
49 n primate OFC signal social information and, if so, how such signals compare with responses to primar
50 variation between the different isolates and if so, how the divergent structures can support similar
51 to what is seen in differentiated cells, and if so, how these altered properties specifically impact
53 are also dependent on CSF1R signalling, and if so, how these cells contribute to disease pathogenesi
54 t role in the chaperoning of syntaxin-1 and, if so, how these dual functions of domain-3a are regulat
56 whether such Vbeta rearrangements occur and, if so, how they might be regulated, we analyzed mice wit
57 whether such strategies are appropriate and, if so, how they should be most effectively implemented.
58 was predictive of future reading skill and, if so, how this brain-behavior correlation informs devel
64 r actin binding reverses this transition and if so, how this reversal is coordinated with actin-activ
65 he lack of clear guidance about whether and, if so, how to return ES/WGS incidental results limits th
67 ligand are actually promoting relapse, and, if so, how we can use this information to adjust our the
79 online as behavioral preferences change and if so, if it is causally linked to specific components o
80 rect interaction between m152 and RAE-1 and, if so, if m152 interacts differentially with the five id
81 ticles (Ag NPs) elicit this same effect and, if so, if the NP itself and/or the dissociation of ionic
93 crust production over the age of the Earth; if so, it is now either a primitive refugium at the core
100 dictate whether an organelle assembles, and, if so, its size, providing a mechanistic link between or
101 ents are in risk of oesophageal perforation, if so, management may be conservative but mediastinal dr
102 gnal that migrates from underlying brain and if so, may implicate newly discovered bridging vessels t
106 ther exploration of mechanistic linkage and, if so, novel therapeutic strategies such as demethylatin
107 e binding of biochemical signals occurs, and if so, on time scales relevant to microbial growth and c
112 croscopic local field potentials (LFPs), and if so, respiratory (r) LFPs could be used to map the fun
117 plex phenotypes in multi-cellular organisms; if so, such rewiring may leave traceable changes in the
124 inst new-onset depression and anxiety and 2) if so, the intensity and amount of exercise required to
128 sion involves a discrete tethering step and, if so, the potential role of GTP hydrolysis and cross-ov
130 t estrogen is combined with progesterone and if so, the type of progesterone used, as well as the rou
131 perature-sensitive phenotype can revert and, if so, the types of substitutions that will emerge (i.e.
134 Statistics on whether patients had died and, if so, their cause of death were available for 7,016 of
136 whether females have a toxic humoral factor; if so, then its strength was compared with that of males
142 to analyzing temporal properties of sounds; if so, then there should be systematic depth-dependent c
146 e asked if they were aware of their VF loss; if so, there were encouraged to describe it in their own
156 ha stimulates insulin synthesis in vivo and, if so, through which mechanism(s) remain largely unknown
158 ding of the mouse and rat hair follicle and, if so, to assess its similarity to that of the rat muscl
160 sure by itself is an etiological factor and, if so, to determine the overall nature of cognitive defi
161 basal state in insulin-resistant muscle, and if so, to determine whether the effects were associated
162 ring goal-directed behaviors for sucrose and if so, to determine whether the two are causally linked.
165 xpression and placental vascularization and, if so, to evaluate the effectiveness of the selective PP
166 h early forms of Alzheimer disease (AD), and if so, to examine the extent and pattern of leakage.
167 rly life can shape senescence schedules, and if so, to examine whether variation among individuals or
168 stomatitis virus (rVSV) vaccine vectors, and if so, to identify strategies by which IL-1beta mediated
170 olytically released from cell membranes and, if so, to identify the responsible sheddase and determin
172 k and urine produced by lactating women and, if so, to quantify typical consumption by breastfed infa
174 ls from the meninges to the spinal cord, and if so, to what extent and through which classes of perip
175 is expressed in insulin-producing cells and, if so, to what extent it affects beta cell function.
176 suicide attempt rates to assess whether, and if so, to what extent, the well-established relationship
177 nhibition may be genetically determined, and if so, transplant recipients should receive personalized
184 ng more often degenerated into re-entry and, if so, was more likely to be sustained for more cycles.
189 other highly chlorinated phenols (HCPs); and if so, what are the major physicochemical factors in det
190 cidal behaviors coaggregate in families and, if so, what are the mechanisms underlying this coaggrega
193 istinctly different motifs on chromatin, and if so, what determines the usage of specific motifs.
195 icient synapses actually occurs in vivo, and if so, what factors regulate it and what role it might p
196 103+ DC even exist in the ocular mucosa, and if so, what functions they have in shaping immune respon
198 ocular surface of normal living rabbits, and if so, what is its efficacy and tolerability versus cycl
199 technology over other novel approaches, and if so, what is the flip side to the use of this technolo
202 is not known whether ATF6 is activated, and if so, what its function is during hypertrophic growth o
203 unclear whether BBB is disrupted in INCL and if so, what might be the molecular mechanism(s) of this
206 T cells are functionally heterogeneous and, if so, what signals specify the differentiation of MP ce
207 it has a role within sympathetic neurons and if so, what target genes it regulates to facilitate targ
209 stinct and specialized neural machinery, and if so, what that machinery's organization might be.
210 lved in response to selective pressure--and, if so, what that pressure might have been--or whether th
211 n directly cause this phenotypic change and, if so, what the signaling mechanism is, were explored in
212 size as part of a regenerative program and, if so, what the underlying mechanism is have remained la
218 rsibly retain a model nanoparticle, ZnO, and if so, what would be the difference between bound ZnO NP
224 share this preference for fair partners and, if so, whether a prospective partner's past fair behavio
225 e contains anergic autoreactive B cells, and if so, whether antigen was encountered during or after t
226 referentially myelinated by glial cells, and if so, whether axo-glial synapses are involved, are long
227 HC contacts promote TCR-MHC specificity and, if so, whether differences exist in TCR V gene compatibi
228 s responses to bacteria in the airspace and, if so, whether differently from its effects in other tis
229 rmine whether an early impairment exists and if so, whether fronto-striatal circuits were associated
230 fers from that found in diseased tissue and, if so, whether glycosylation affects inhibitor binding.
231 ignaling is functional in P2X-dblKO mice and if so, whether it activates the primary viscerosensory n
232 vity can be detected in oral fluid (OF) and, if so, whether it correlates with SCRA concentrations.
233 if an airway microbiome exists at birth and if so, whether it is associated with subsequent lung dis
234 the in the spinal cord gray matter (GM), and if so, whether it is because of an aberrant increase in
235 nduces IFN-beta from myeloid phagocytes, and if so, whether it is helpful or harmful to the host to d
236 DTic human cardiac effect indeed exists, and if so, whether it is specific to JDTic or represents a K
237 dorsal and ventral progenitor lineages and, if so, whether it regulates common or unique networks of
238 SDB) is different from healthy children and, if so, whether it resolves with treatment, we used heart
239 ating exercise-induced cardioprotection, and if so, whether its activation independent of exercise ca
240 bone abnormalities associated with MDD and, if so, whether ketamine treatment corrected the abnormal
241 nterregulatory response to hypoglycemia, and if so, whether knockdown of in the VMH can improve count
242 r RB1 mutation drives tumor progression and, if so, whether loss of pRb/E2f interaction is responsibl
244 th sites can be simultaneously occupied, and if so, whether monobodies bind independently or cooperat
245 educing death and disability at 90 days, and if so, whether oxygen given at night only, when hypoxia
247 r these beneficial and harmful effects, and, if so, whether PDE3 can be targeted so as to increase co
248 y rings affect AML strains in patients, and, if so, whether ring-induced perturbations in leaflet str
249 onal (i.e., intracellular) consequences and, if so, whether such consequences are associated with inc
250 ytic function of the proteasome in mice and, if so, whether the enhancement can rescue a bona fide pr
251 (CT Topo I) on a native supercoiled DNA and, if so, whether the enzyme catalyzes its subsequent equil
252 with sigma(70) R4 at class II promoters and, if so, whether the interactions occlude the binding of s
253 n an isolated monolayer of copper oxide, and if so, whether the two-dimensional superconductivity and
254 re generic to the REFeAsO-type materials and if so, whether their exact topology is responsible for t
255 resented among myocardial sphingolipids and, if so, whether their function and metabolic routes were
256 hether humans eating eggs generate TMAO and, if so, whether there is an associated increase in a mark
257 ligand to activate VMH EphA5 receptors, and if so, whether these changes could contribute to pathoge
259 network can have preferred frequencies and, if so, whether these frequencies are the same or correla
260 ents express functional 5-HT3 receptors and, if so, whether these receptors play a role in transmissi
261 tations may be a cortex-wide phenomenon and, if so, whether these representations can be organized in
262 very different class of drug (ethanol), and if so, whether these systems might be involved in their
263 anglion cells (DSGCs) exist in primates and, if so, whether they are the equivalent to mouse and rabb
264 normal and diseased parathyroid glands, and if so, whether they had any functional effects on parath
265 alogous approach-avoidance dispositions and, if so, whether they share a homologous neurobiological s
267 ents, could be observed during encoding and, if so, whether they would predict different levels of ac
268 s in neurons leads to cell-cell fusion, and, if so, whether this affects neuronal fate, function, and
269 targets change during tumor progression and, if so, whether this affects precision medicine trial des
270 adverse metabolic profiles in offspring, and if so, whether this association is causal, via intrauter
271 agged adult cardiac tissue progenitors, and, if so, whether this cell-based signal could serve as a q
272 mation needed to restore these patterns-and, if so, whether this could improve tissue function-is not
273 increase hepatic inflammatory signaling and if so, whether this effect 1) involves activation of Kup
275 r readmission rates than white patients, and if so, whether this effect was mediated by the hospitals
277 les during genomic surveillance in vivo and, if so, whether this is done via direct or indirect means
278 whether climate variability is changing, and if so, whether this is due to anthropogenic forcing, are
279 d with greater adiposity into adulthood, and if so, whether this is via intrauterine mechanisms or sh
280 dark toward haptically explored objects (and if so, whether this reactivation might be due to imagery
281 nimals are placed in a cold environment and, if so, whether this response is required for the associa
282 trophin modulated the expansion of OPCs and, if so, whether this was effected through the serial enga
283 ine whether the patient was followed up and, if so, whether treatment was initiated and/or symptoms w
284 e coagulation activation in heat stroke and, if so, whether upstream inhibition of coagulation activa
286 essels associated with brain metastases, and if so, whether VCAM-1-targeted MRI enables early detecti
288 t of stress on brain gray matter volume and, if so, which brain regions mediate the effect of this ge
289 n support memory-guided decision making and, if so, which brain regions play a role in compensation.
290 n significantly improve detection power, and if so, which covariates are more relevant for EWAS data.
291 oxidation and esterification in the MBH and, if so, which hypothalamic cell type(s) and intracellular
292 determine if an enhancement is indicated and if so, which method will be the safest and most efficaci
294 g as a marker of recent neural activity and, if so, which of its many gene targets underlie circuit r
295 ther OXTR is truly associated with ASD, and, if so, which OXTR single-nucleotide polymorphisms (SNPs)
296 x vaccination is driving the phenomenon, and if so, why is re-emergence not universal throughout the
300 xplain the emergence of drug resistance, and if so, would have prognostic and predictive utility.