ライフサイエンスコーパス: illicit

1 te of action of opioid drugs, both licit and illicit.

2 le tissue is a valid marker for detection of illicit 17beta oestradiol and/or dexamethasone use in be

3 es in Xenopus oocytes, both Ca(2+) and Na(+) illicit 5-HT-induced currents in the Asn-101 mutants and

4 which can be used as potential biomarkers of illicit 5-nitroimidazole abuse.

5 sist in the identification and evaluation of illicit activities and provide information that would he

6 tool to study suspected cases of sex steroid illicit administration in veal calves, complementary to

7 Millions of individuals have used illicit anabolic-androgenic steroids (AAS), but the long

8 weeks, which was defined as abstinence from illicit and non-prescribed opioids and cocaine in the pa

9 atment-resistant patients abstain from using illicit and non-prescribed opioids and cocaine.

10 Illicit and nonmedical (use in ways other than instructe

11 eling interventions to prevent initiation of illicit and nonmedical drug use among adolescents and yo

12 oral interventions in reducing self-reported illicit and pharmaceutical drug use among adolescents.

13 Substance use disorders involving illicit and prescription drugs are a serious public heal

14 For problem use of illicit and prescription drugs, sensitivity ranged from

15 The abuse of opioid drugs, both illicit and prescription, is a persistent problem in the

16 racies in histories, and determining how the illicit beverage was shared.

17 There is a shift in the production of illicit cannabis plant material from regular marijuana t

18 Overall, the potency of illicit cannabis plant material has consistently increas

19 xamines the concentration of cannabinoids in illicit cannabis products seized by the U.S. Drug Enforc

20 Over the last 25 years, illicit cannabis use and cannabis use disorders have inc

21 have contributed to increased prevalence of illicit cannabis use and cannabis use disorders.

22 In the earlier period, illicit cannabis use and disorders decreased similarly i

23 Past-year illicit cannabis use and DSM-IV cannabis use disorder.

24 Overall, from 1991-1992 to 2012-2013, illicit cannabis use increased significantly more in sta

25 Little is known about MML and adult illicit cannabis use or cannabis use disorders considere

26 d price policies are undermined by licit and illicit cheap supplies.

27 statistical analyses can be used to classify illicit cocaine as originating from one of 19 growing re

28 est available, authoritative data source for illicit cocaine flows.

29 entify the types of sewage overflows and the illicit connection status of drainage systems.

30 ys for the specific detection of a family of illicit designer drugs, the synthetic cathinones, with c

31 r to single-stranded telomere DNA to prevent illicit DNA damage responses and to enhance telomerase-m

32 hypertension, liver disease, renal disease, illicit drug abuse, and poor performance status, but low

33 ne dependence; alcohol abuse/dependence; and illicit drug abuse/dependence.

34 ral drug residues, including the potentially illicit drug amphetamine, at 6 stream sites along an urb

35 ysical processes on the transformation of 30 illicit drug and pharmaceutical residues were quantified

36 y metabolic processes) and transformation of illicit drug biomarkers (secondary metabolic processes)

37 es most health burden in eastern Europe, and illicit drug burden is higher in the USA, Canada, Austra

38 ted 50% of adolescents in the US had used an illicit drug by the time they graduated from high school

39 nfectious and noninfectious complications of illicit drug can expedite diagnosis and medical treatmen

40 Synthetic cannabinoids are an emerging illicit drug class.

41 control groups for genetic investigations of illicit drug dependence.

42 endence, including extension of liability to illicit drug dependence.

43 to identify CAS of forensic significance for illicit drug detection, profiling, and attribution.

44 ce of other cutting agents commonly found in illicit drug formulations.

45 Cannabis is the most widely used illicit drug globally, and users are at increased risk o

46 field can provide an unbiased look into the illicit drug habits of large populations as well as spec

47 Cannabis is categorized as an illicit drug in most US states, but legalization for med

48 Marijuana is the most widely used illicit drug in the United States and all over the world

49 Marijuana is the most commonly used illicit drug in the United States, but little is known a

50 Cocaine is the second most abused illicit drug in the United States.

51 phetamine is the second most frequently used illicit drug in the United States.

52 Cannabis is the most widely used illicit drug in the world.

53 rdless of the type of normalization as daily illicit drug loads appeared to vary substantially more t

54 opulation is negligible compared to those of illicit drug loads.

55 The illicit drug methylamphetamine is often prepared from th

56 Number of times illicit drugs were used; any illicit drug or any cannabis use.

57 ehavioral interventions to prevent or reduce illicit drug or nonmedical pharmaceutical use in childre

58 its analogues as contaminating materials in illicit drug products presents a major hazard to first r

59 ng the distribution channel and avoiding the illicit drug reaching the end-user.

60 Attribution of the origin of an illicit drug relies on identification of compounds indic

61 As part of the Illicit Drug Reporting System study, PWIDs reported syri

62 anding field that can provide information on illicit drug usage in communities, based on the measured

63 ng (adjusted OR 1.74, 95% CI 1.08-2.81), any illicit drug use (1.72, 1.07-2.79) and weekly cannabis u

64 (OR 2.14, 95% CI 1.04-4.41; p=0.038), other illicit drug use (2.17, 1.10-4.27; p=0.025), sleep probl

65 nnabis use (2.61, 1.11-6.14; p=0.029), other illicit drug use (2.47, 1.02-5.96; p=0.045), exposure to

66 on (6.1% vs. 3.7% males, Z=2.58, p<0.05) and illicit drug use (3.3% vs. 0.6% males with drug abuse, Z

67 0 [15%]), excessive drinking (34 [26%]), and illicit drug use (38 [29%]).

68 ratio 4.81; 95% CI 2.03-11.36, p=0.0005) and illicit drug use (4.75; 1.19-18.96, p=0.026) were signif

69 ntiretroviral therapies (63%-79%) and active illicit drug use (53%-55%).

70 Intravenous illicit drug use (IDU) and hepatitis C infection (HCV) c

71 y associated with chronic HCV infection were illicit drug use (including injection drugs) and receipt

72 r statistically significant association with illicit drug use (standardized mean difference, -0.08 [9

73 evidence- and human rights-based response to illicit drug use and associated infectious diseases.

74 , alcohol use and recent suicidal behaviour, illicit drug use and depression, depression and inconsis

75 vels of miRNA-34a correlated positively with illicit drug use and ethanol consumption.

76 do not support widespread implementation of illicit drug use and prescription drug misuse screening

77 ally in screening and brief intervention for illicit drug use and prescription drug misuse, based in

78 Furthermore, we show differential effects of illicit drug use and prolonged freezing on SE-mediated H

79 tly accounted for 35% of the heritability in illicit drug use and, when combined with common variants

80 One trial (n=322) found a reduction in illicit drug use at 38 months (eg, cannabis use in the p

81 Illicit drug use can result in a wide range of medical c

82 verage 16 times higher, major depression and illicit drug use disorder prevalence were both six times

83 e potential effects of alcohol, tobacco, and illicit drug use during this period on: social, psycholo

84 Illicit drug use had the highest PAFs associated with AC

85 Illicit drug use has a global concern and effective moni

86 The effects on illicit drug use in 26 trials among nonpregnant youth (n

87 primary care-based interventions to prevent illicit drug use in children, adolescents, and young adu

88 7.9% of persons aged 12 to 17 years reported illicit drug use in the past month, and an estimated 50%

89 Per capita illicit drug use increased significantly during the moni

90 Illicit drug use is among the most common causes of prev

91 Illicit drug use is associated with many negative health

92 ncentration, intensity/size) irrespective of illicit drug use or duration of semen freezing.

93 lements may be needed for patients reporting illicit drug use or who have unmet needs.

94 ous diseases specialists-to complications of illicit drug use that may be underrecognized.

95 ression to 1.92 (1.79-2.04) for anxiety; for illicit drug use they ranged from 1.36 (1.25-1.49) for a

96 000, being married or living as married, and illicit drug use were independently associated with incr

97 immediate withdrawal symptoms and replacing illicit drug use with long-acting opiate drugs.

98 Age, HIV infection, illicit drug use, and CNS opportunistic infections all c

99 ntal health problems, daily tobacco smoking, illicit drug use, and dependence were all more common in

100 dictors of USA300 included HIV, younger age, illicit drug use, and male sex; all but 1 colonized indi

101 isk behaviors including smoking, alcohol and illicit drug use, and sexual risk-taking.

102 models that adjusted for time-variant (other illicit drug use, antipsychotic medication adherence) an

103 ous variants may be important in etiology of illicit drug use, but detection of individual variants w

104 havioral counseling interventions to prevent illicit drug use, including nonmedical use of prescripti

105 with an HBV or HCV patient, >1 sex partner, illicit drug use, or incarceration (21% of cases versus

106 enied a history of contact with sick people, illicit drug use, or recent travel.

107 ast 30 years, cigarette smoking, alcohol and illicit drug use, sexual activity, and violent behavior

108 ed RR for risk factors (harmful alcohol use, illicit drug use, smoking, and obesity) and causes of il

109 Among PLWH who report illicit drug use, we evaluated associations between HIV

110 18 to 25 years have a higher rate of current illicit drug use, with an estimated 23.2% currently usin

111 ng, physical inactivity, unhealthy diet, and illicit drug use-according to CHC after adjusting for so

112 cigarette smoking, alcohol consumption, and illicit drug use.

113 lts were stratified by unhealthy alcohol and illicit drug use.

114 thy alcohol use and 28.4% reported past-year illicit drug use.

115 stolic BP relation was partially mediated by illicit drug use.

116 is low and associated with being UK born or illicit drug use.

117 e lower in patients reporting unmet needs or illicit drug use.

118 rs (HAND), which is typically exacerbated by illicit drug use.

119 mmonly encountered adverse ocular effects of illicit drug use.

120 uld acknowledge high rates of depression and illicit drug use.

121 biomarker-based sensitivity of self-reported illicit drug use.

122 , obesity, harmful alcohol use, smoking, and illicit drug use; n = 4,917).

123 f positive-negative samples and the specific illicit drug used by abusers in a single "click".

124 Cannabis is the most prevalent illicit drug used by adolescents worldwide.

125 MDMA (Ecstasy) is an illicit drug used by young adults at hot, crowed "rave"

126 Importance: Methamphetamine is a common illicit drug used worldwide.

127 mmunity-recruited cohort of HIV-seropositive illicit drug users during a community-wide ART expansion

128 espite cannabis being the most commonly used illicit drug worldwide, a MALDI-MS method for the detect

129 As the most widely used illicit drug worldwide, and as a source of numerous unde

130 Cannabis is the most commonly used illicit drug worldwide, and use is typically initiated d

131 Use of Cannabis, the most widely used illicit drug worldwide, is associated with acute anxiety

132 Cannabis is the most commonly used illicit drug worldwide.

133 While THC is an illicit drug, CBD and CBG are legal substances that have

134 though marijuana is the most commonly abused illicit drug, the implications of legalized, widespread,

135 to study the electrochemical behavior of the illicit drug, thus profiling the different oxidation sta

136 he U.S.A., cocaine is the second most abused illicit drug.

137 [34.7%]) and recent use of cocaine or other illicit drugs (39 [13.5%]) were the most common causes o

138 dependence (17.95, 9.44-34.12), use of other illicit drugs (7.80, 4.46-13.63), and suicide attempt (6

139 ables the separation of powdered mixtures of illicit drugs (cocaine, methamphetamine, heroin, fentany

140 se in young people for tobacco, alcohol, and illicit drugs (eg, cannabis, opioids, amphetamines, or c

141 ine aura (seven patients) and consumption of illicit drugs (five, no hallucinogens) were rare.

142 A), benzylamines (mono-, di-, and tri-), and illicit drugs (MA, MDEA, and haloperidol).

143 up of neighborhood controls not dependent on illicit drugs (n = 340), 3 SNPs were significantly assoc

144 ed as legal alternatives to more established illicit drugs (pragmatically clustered and termed new ps

145 its effect among HIV-positive people who use illicit drugs (PWUD) has yet to be evaluated.

146 DR patterns and impacts among people who use illicit drugs (PWUD).

147 In this study, select illicit drugs (six drugs and eight metabolites) were det

148 trochemical detection of the most prevailing illicit drugs (such as cocaine, heroin, and (meth)amphet

149 ng therapy (15% cannabinoids alone; 8% other illicit drugs +/- cannabinoids).

150 to impact consumption of pharmaceuticals and illicit drugs - a priori to an unknown extent.

151 commercial linear ion trap using mixtures of illicit drugs and acylcarnitines.

152 pointments, and two studies on abstinence of illicit drugs and alcohol use to prevent the reoccurrenc

153 o used to detect trace chemical compounds in illicit drugs and explosives, in which samples were obta

154 The detection and mapping of illicit drugs and metabolites in latent fingermarks woul

155 ovide dynamic population normalized loads of illicit drugs and pharmaceuticals during a known period

156 Interestingly, illicit drugs and prolonged freezing decreased the level

157 However, the effect of illicit drugs and prolonged freezing on SE bioactivity i

158 ry mixtures of ketamine with adulterants and illicit drugs are analyzed with SWV to investigate the e

159 Some illicit drugs are associated with rare infections, which

160 Using several illicit drugs as analytes, the work presented here descr

161 "turn-on" fluorescence detection of multiple illicit drugs at low micromolar concentrations in water

162 ble from ION-1 for retrospective testing for illicit drugs by enzyme-linked immunosorbent assay.

163 ting per capita consumption of, for example, illicit drugs by means of wastewater analysis (sometimes

164 ange of use for various classes of licit and illicit drugs by monitoring Athens' wastewater from 2010

165 The costs associated with obtaining illicit drugs can fluctuate depending upon the relative

166 genetic datasets for alcohol, nicotine, and illicit drugs contain the family of KCNN genes.

167 % had consumed alcohol and 5% had used other illicit drugs during the first half of pregnancy.

168 pants in the ION-1 trial, 23% (n = 196) used illicit drugs during therapy (15% cannabinoids alone; 8%

169 e availability, synthesis, and popularity of illicit drugs evolve over time, new syndromes associated

170 t colorimetric presumptive identification of illicit drugs for determining illegal possession of cont

171 nonuse, asymptomatic use, and problem use of illicit drugs for U.S. adults in the general household p

172 The removal efficiencies of illicit drugs from the two WWTPs ranged from 4% (norcoca

173 The environmental emission of illicit drugs from WWTP discharges was calculated to ran

174 production, trafficking, and consumption of illicit drugs have been constantly growing, leading to h

175 e effects of controlled neuropsychiatric and illicit drugs have been forensically identified in the U

176 mework of appetitive behavior, the view that illicit drugs hijack reward circuits by hyperactivating

177 racy was achieved for the direct analysis of illicit drugs in 4 muL of raw blood, serum, and whole ur

178 achieved in the analysis of therapeutic and illicit drugs in 5 muL samples.

179 The presence of pharmaceuticals, including illicit drugs in aquatic systems, is a topic of environm

180 oxins in soil samples, the identification of illicit drugs in human blood, and the quantitation of ac

181 eveloped for the "lab-on-click" detection of illicit drugs in nonpretreated oral fluids, and a novel

182 ound to predict the concentrations of select illicit drugs in raw wastewater (r(2) = 0.20-0.79; p </=

183 The consumption rate of target illicit drugs in the communities served by the two WWTPs

184 tory of injection drug use, and had used any illicit drugs in the past 12 months were recruited at ne

185 are purchased as alternatives to traditional illicit drugs of abuse and are manufactured to circumven

186 ility, where they maintained abstinence from illicit drugs of abuse and received behavioral therapy f

187 However, it is unknown whether, akin to illicit drugs of abuse such as cocaine or heroin, the ad

188 for the spatially resolved quantification of illicit drugs on the surface of a fingerprint using time

189 omes (SE) from healthy donors who do not use illicit drugs potently inhibit HIV-1.

190 The percentage of participants using illicit drugs ranged from 2.3% to 38.6% in the control g

191 amphetamine; MDA) times higher mass flows of illicit drugs than did the WWTP that served a smaller po

192 Spatially resolved quantification of illicit drugs using imaging mass spectrometry is possibl

193 Number of times illicit drugs were used; any illicit drug or any cannabi

194 personal care products, pharmaceuticals, and illicit drugs) in wastewater effluent.

195 (nicotine, caffeine, alcohol, cannabis, and illicit drugs) was obtained for 8586 twins who were regi

196 scale consumption of chemicals, particularly illicit drugs, across different communities and over tim

197 nt presumptive colorimetric field-testing of illicit drugs, allowing for an objective and user-friend

198 tidepressants, QT-prolonging drugs, opiates, illicit drugs, and dyslipidemia.

199 n of chemical warfare agent (CWA) simulants, illicit drugs, and explosives is demonstrated at nanogra

200 (at room temperature), including pesticides, illicit drugs, and explosives, were selected to evaluate

201 smitters, phosphopeptides, oligonucleotides, illicit drugs, and pharmaceutical compounds are successf

202 timate the population level use of licit and illicit drugs, new psychoactive substances, human exposu

203 uting child abuse content, selling or buying illicit drugs, or sharing malware online.

204 nalysis of a wide range of compounds such as illicit drugs, pharmaceuticals, and pesticides-such that

205 es (mass <50 mg), with low concentrations of illicit drugs, present a particular challenge to analysi

206 ty degree, cannabis dependence, use of other illicit drugs, suicide attempt, depression, and welfare

207 use, with an estimated 23.2% currently using illicit drugs.

208 ) and methamphetamine (MA) are widely abused illicit drugs.

209 acteremia and recent use of cocaine or other illicit drugs.

210 legal drugs promotes subsequent addiction to illicit drugs.

211 cco and alcohol usually preceding the use of illicit drugs.

212 s, such as sex workers and people who inject illicit drugs.

213 ith those who used cannabinoids and/or other illicit drugs.

214 dies have examined the ecological effects of illicit drugs.

215 tobacco use, but are not available to target illicit drugs.

216 ee release areas, and to be current users of illicit drugs.

217 drugs were involved in more deaths than were illicit drugs.

218 the top-named drugs and for prescription and illicit drugs.

219 site multicompound quantitative screening of illicit drugs.

220 and the use/misuse of nicotine, alcohol, and illicit drugs.

221 he chemical analysis of sewage biomarkers of illicit drugs.

222 of explosives, chemical warfare agents, and illicit drugs.

223 identification of salt-tolerant sensors for illicit drugs.

224 d into the aquatic ecosystem corresponded to illicit drugs/controlled substances such as ketamine and

225 shonest athletes aiming at an artificial and illicit enhancement of their endurance performance.

226 ed worldwide due to the widespread access to illicit fentanyl and its potent analogues.

227 Illicit fentanyl use is associated with sudden death.

228 thod is also applicable to the detection of (illicit) gene regulation through the identification of c

229 places are websites that facilitate trade in illicit goods, mainly using Bitcoin.

230 edication, leading to massive diversion into illicit markets.

231 Moreover, misuse of prescription and illicit narcotics has resulted in the current opioid cri

232 cal classifications, the proportion of often illicit Onion/Hidden Services use is more prevalent (~7.

233 ffers a tool for tackling a broader class of illicit online behaviours(21,22) such as financial fraud

234 The substantial increase in prescription and illicit opioid abuse observed over the last 2 decades ha

235 Reducing frequency of illicit opioid or methamphetamine/crystal use without ab

236 Reducing frequency of illicit opioid or methamphetamine/crystal use without ab

237 iated with significantly lower odds of daily illicit opioid use (adjusted odds ratio 0.50, 95% CI 0.3

238 iation between frequency of cannabis use and illicit opioid use among people who use drugs (PWUD) exp

239 n between frequent cannabis use and frequent illicit opioid use among PWUD with chronic pain.

240 may serve as an adjunct to or substitute for illicit opioid use among PWUD with chronic pain.

241 nt (OAT) can be highly effective in reducing illicit opioid use and improving multiple health and soc

242 patients completing DAA therapy with active illicit opioid use at intake, 14 (46.4%) engaged in opio

243 s negative urine samples and self-reports of illicit opioid use from week 5 to week 24, analysed in t

244 norphine group reduced the number of days of illicit opioid use per week from 5.4 days (95% CI, 5.1-5

245 In total, 455 (40%) reported daily illicit opioid use, and 410 (36%) reported daily cannabi

246 n addiction treatment, reduced self-reported illicit opioid use, and decreased use of inpatient addic

247 tion-assisted treatment is a key to reducing illicit opioid use, preventing opioid overdose deaths, a

248 The percentage of participants negative for illicit opioid use, retention, naltrexone ingestion, and

249 Self-reported days of illicit opioid use, urine testing for illicit opioids, h

250 urine results, abstinence, and time to first illicit opioid use.

251 nt, still show many individuals relapsing to illicit opioid use.

252 once or more per day) cannabis use and daily illicit opioid use.

253 th 95% CI, -4.9 to -1.5; P < .001) and other illicit opioids (mean difference, -2.7 with 95% CI, -4.6

254 significantly lower use of heroin and other illicit opioids in the extended-release naltrexone group

255 Fewer women treated with BMT used illicit opioids near delivery (risk ratio=0.44, 95% CI:

256 In addition, reducing use of illicit opioids or methamphetamine/crystal, even without

257 g each drug at baseline ranged from n = 568 (illicit opioids) to n = 4272 (marijuana).

258 ays of illicit opioid use, urine testing for illicit opioids, human immunodeficiency virus (HIV) risk

259 tween HIV viral load (VL) and reduced use of illicit opioids, methamphetamine/crystal, cocaine/crack,

260 nd number of days of use of heroin and other illicit opioids.

261 eatment, but many patients do not stop using illicit or non-prescribed drugs concomitantly.

262 pants were treatment resistant (ie, had used illicit or non-prescribed opioids or cocaine on one or m

263 als are shifting towards approaches that can illicit osteoinductive properties.

264 nionic surfactant sodium decyl sulfate (SDS) illicited PFAA chain-length dependent impacts in two neg

265 Recent reports suggest illicit pregabalin (Lyrica) use may be increasing among

266 tible with botulism after drinking pruno, an illicit, prison-brewed alcoholic beverage.

267 Cannabis is the most frequently used illicit psychoactive substance worldwide; around one in

268 Exclusion criteria were the use of illicit psychotropic substances, mental confusion, hepat

269 ervices that are disproportionately used for illicit purposes.

270 zole SCs which are currently the predominant illicit smoking mixtures on the drug market is performed

271 -related legal issues (+2 points), and prior illicit substance abuse (+1 point).

272 past or current history of cocaine or other illicit substance abuse.

273 data provides the first indication that this illicit substance can have major implications on renal f

274 detectors that are in use for hazardous and illicit substance detection are subject to false-positiv

275 In young men aged 20-24 years, alcohol and illicit substance use are responsible for 14% of total h

276 (e.g., precocious sexual activity, bullying, illicit substance use).

277 y disorder, smoking and alcohol consumption, illicit substance use, ever having separated from a long

278 en the treatment groups regarding most other illicit substance use.

279 short-term abstinence from heroin and other illicit substances and should be considered as a treatme

280 maintaining abstinence from heroin and other illicit substances in newly detoxified individuals.

281 free from all pharmacological treatments and illicit substances show cortical glutamatergic alteratio

282 mine (MA) is one of the most commonly abused illicit substances worldwide.

283 ints included number of days of use of other illicit substances.

284 ic medications, and no current dependence on illicit substances.

285 idely implemented tools for the detection of illicit substances.

286 naive to all pharmacological treatments and illicit substances.

287 chronicity or the use of antipsychotics and illicit substances.

288 ounds designed to mimic the effects of other illicit substances.

289 ed by an inexpensive, readily available, and illicit supply of synthetic opioids.

290 nist MDMB-Fubinaca (FUB), a recently emerged illicit synthetic cannabinoid infused in street drugs th

291 come countries, a result in no small part of illicit trade and cheap products from China and other un

292 Combating illicit trafficking of Special Nuclear Material may requ

293 x present in many immune populations and can illicit transcriptional responses that vary among differ

294 In the later period, illicit use increased by the following percentage points

295 developed for the routine monitoring of the illicit use of clenbuterol in animal farming.

296 the prescribing of opioids for pain and the illicit use of fentanyl (and derivatives) have contribut

297 ress targeted controls on farms suspected of illicit use of growth promoters.

298 data from PWID aged 18-64 years who reported illicit use of opioids (n = 9957) in the past 12 months.

299 Thus, monitoring the illicit use of rHuEPO among athletes is crucial in ensur

300 e advantages also potentially facilitate the illicit use of the CRISPR/Cas system in order to achieve