ライフサイエンスコーパス: imbalance

1 smus), stereoacuity, and postural stability (imbalance).

2 ealthy despite significant X-autosome dosage imbalance.

3 eased M2 macrophages and escalated microbial imbalance.

4 baw mini-pigs, implying aggravated autonomic imbalance.

5 drological cycle, and the planet's radiation imbalance.

6 cell-specific mechanisms to counteract redox imbalance.

7 ression by integrating signatures of allelic imbalance.

8 nsteadily by psychological and physiological imbalance.

9 algorithms endowed with robustness to gender imbalance.

10 ity in response to signals of PG homeostasis imbalance.

11 ease comparable to the 0.6 PgC yr(-1) budget imbalance.

12 opy-number loss or by an unexplained allelic imbalance.

13 tic and epigenetic, that explain the allelic imbalance.

14 y, empirical relationships, and case-control imbalance.

15 sed basal colonic inflammation and microbial imbalance.

16 type in any data that might exhibit allelic imbalance.

17 ting that chronic stress may precipitate E/I imbalance.

18 studies, possibly because of nucleotide pool imbalance.

19 pathogenesis is associated with a Th17/Treg imbalance.

20 the underlying cause of LC on the resultant imbalance.

21 tion of adipose tissue due to chronic energy imbalance.

22 and calcification in the context of mineral imbalance.

23 intestinal barrier dysfunction and commensal imbalance.

24 RUSBoost for alleviating the involved class imbalance.

25 ormance instead of AUROC when the dataset is imbalanced.

26 l symptoms that accompany systemic acid/base imbalances.

27 of neuroscience articles show marked gender imbalances.

28 ingly attempted to confront pervasive gender imbalances.

29 sed on broad CNA scores and discrete genomic imbalances.

30 dy was limited by small numbers and baseline imbalances.

31 abolic homeostasis including energy or redox imbalances.

32 activity is more likely to occur during E/I imbalances.

33 s 68,0000 candidates) and had a larger class imbalance (2.5% positives vs 5% positives) as compared t

34 tion of 5.8S and 18S rRNA precursors, and an imbalanced 40S:60S ribosome subunit ratio.

35 Imbalanced 5-HT1A/2A activation, either through receptor

36 a with the SSC, mitochondrial fission/fusion imbalance, a remarkable reduction in mitochondrial and c

37 entist might still be needed to tackle class imbalance-a common challenge in ML classification using

38 es identified a pattern of increased allelic imbalance across the entire X chromosome in SLE lymphocy

39 us disciplines, even while access to them is imbalanced across global settings.

40 Osteoporosis arises from imbalanced activity of osteoclasts and osteoblasts.

41 Notably, macroH2A1 splice variant imbalance affected alt-EJ capacity also in tumor cells.

42 ptor dysfunction, neuroinflammation or redox imbalance, all appear to converge towards an oxidative s

43 cingulate cortex (rACC) tracked the level of imbalance among goals, whereas the ventromedial prefront

44 affect our interpretation of stoichiometric imbalances among microbes and soils and are highly relev

45 lpha2delta subunits to excitatory/inhibitory imbalance and aberrant network connectivity characterist

46 highlight the need to account for co-factor imbalance and confirm that better-balanced pathways with

47 to AGEs in the liver promotes an AGER1/RAGE imbalance and consequent redox, inflammatory, and fibrog

48 study provides evidence linking nutritional imbalance and exposure to TCS with the progression of NA

49 a regulatory role in the observed metabolic imbalance and hypothalamic inflammation in mouse primary

50 e to define mechanisms of Treg subpopulation imbalance and identify potential for therapeutic interve

51 , altered brain metabolism, neurotransmitter imbalance and impaired neuronal network connectivity.

52 regulation of aspartate kinase, causing flux imbalance and lysine and DAP accumulation.

53 proteins, and changes in intracellular ionic imbalance and membrane organization.

54 ic option to treat patients with electrolyte imbalance and nutrient malabsorption.

55 Herein, we tested whether the angiogenic imbalance and oxidative stress in the preeclamptic place

56 Redox imbalance and oxidative stress-related biomarkers are ra

57 These mice, with excitatory/inhibitory imbalance and short life-span, yielded a remarkable surv

58 The most striking phenotypes-gender imbalance and splenic marginal zone B-cell lymphoma-emer

59 er and lung; this finding identifies tension imbalance and tissue curvature as fundamental determinan

60 (studies 9A and 9B), which may result in an imbalanced and inefficient provision of resources to the

61 Our findings identify DDR mutations, histone imbalances and aberrant subtelomeric chromatin as interc

62 ents with MDS for TP53 mutations and allelic imbalances and delineated two subsets of patients with d

63 monal activation, oxidative stress, hormonal imbalance, and abnormal immune cell signaling.

64 ice occurs, which causes intracellular ionic imbalance, and in turn, membrane swelling that potential

65 uency of these distant propagating ecosystem imbalances appears to be growing.

66 hat TP53 mutations and the extent of genomic imbalances are associated with poor outcome in younger b

67 tent with this notion, excitation-inhibition imbalances are considered a pathophysiological mechanism

68 At maximal speed, higher imbalances are related to poorer performances.

69 underlying CHD gene regulatory network (GRN) imbalances are unknown.

70 aired neuronal processes, including dopamine imbalance, are central to the pathogenesis of major psyc

71 est that frontal versus posterior functional imbalance as measured by ALFF is a novel putative trans-

72 nterfacing, to propose 'subcellular lipidome imbalance' as a likely common pathomolecular theme in MN

73 y (TBI) can result in excitation: inhibition imbalance, as well as a range of chronic neurological de

74 Our results confirm dramatic redox imbalance, associated with impaired antioxidant defenses

75 es that were defined a priori or that showed imbalance at baseline.

76 ased propensity for TT luminal concentration imbalances at high electrical stimulation rates would be

77 The interaction and imbalance between ACE and ACE2 result in an unopposed an

78 a change in the chondrocyte phenotype and an imbalance between anabolic and catabolic processes.

79 Existing studies show that the imbalance between cell proliferation and apoptosis is cl

80 rcise, can yield important information about imbalance between delivery and consumption.

81 The striking imbalance between disease incidence and mortality among

82 in epilepsy, a disorder characterized by an imbalance between excitation/inhibition.

83 with differentiating patterns of functional imbalance between frontal and posterior brain regions, a

84 n of a functional beta cell mass but also an imbalance between its activated state and its microenvir

85 ophysiology of ASD.SIGNIFICANCE STATEMENT An imbalance between neural excitation and inhibition, resu

86 An imbalance between neuropeptides that promote stress and

87 geneous populations, results suggest that an imbalance between nutrient efficacy and chemotactic supe

88 The resulting imbalance between ongoing injury and restitution led to

89 d rats has been proposed to contribute to an imbalance between pattern separation and pattern complet

90 In periodontitis-affected tissues, the imbalance between T-helper type-17 (Th17) and T-regulato

91 The mass-imbalance between the plastic litter supplied to and obs

92 umer growth penalty was driven by not only P imbalance between trophic levels but also imbalances in

93 recognition of 'different' cells, signalling imbalances between distinct cell populations and the mec

94 lying circuit defects.SIGNIFICANCE STATEMENT Imbalances between neural excitation and inhibition are

95 ature strain are induced by lateral pressure imbalances between the constituent lipids and drive key

96 nitor cells can lead to clonal expansion and imbalanced blood cell production.

97 r somatic copy number aberration and allelic imbalance burdens are identified in metastases.

98 enzymes that alleviates intracellular redox imbalances by directly targeting circulating redox-coupl

99 reg cells over effector T cells and how this imbalance can be overcome.

100 erobes such as Proteobacteria This microbial imbalance can contribute to disease pathogenesis by eith

101 ficant, dynamic, compartment-based DRM ratio imbalance can exist, as it has the potential to go unnot

102 Confounding sex imbalances can create the appearance of a maternal effec

103 udies have highlighted the role of ER Ca(2+) imbalance caused by dysfunction of sarco/ER Ca(2+) ATPas

104 t, through revealing the source of co-factor imbalance CBA can facilitate pathway and host selection

105 t risk of developing, ovarian cancer have an imbalanced cervicovaginal microbiome.

106 Challenges included training on highly imbalanced classes and predicting multiple labels per im

107 ous thoracic diseases under different gender imbalance conditions.

108 llular DMSP did not respond to metabolically imbalanced conditions, while Thalassiosira oceanica intr

109 trategies aimed at modulating this Th17/Treg imbalance could eventually arrest the RANKL-mediated alv

110 This imbalance could potentiate glutamate excitotoxicity and

111 limitation to resolve nutrient supply-demand imbalances, critical for diabetes and cancer.

112 the massive growth of high-dimensional class-imbalanced data across many scientific fields.

113 est our method against insufficient data and imbalanced data issues and demonstrate that Poly(A)-DG n

114 This paper utilized an imbalanced data set of 24,434 with (69.71%) non-hyperten

115 can not be simply used for addressing class-imbalanced data without any adjustment.

116 ique must be developed for complicated class-imbalanced data, especially in the context of high-dimen

117 selection method for high-dimensional class-imbalanced data, which is simple and can be an alternati

118 ve for performing feature selection in class-imbalanced data.

119 re selection applied it to complicated class-imbalanced data.

120 are essential to Lp, allowing it to grow in imbalanced diets.

121 ced in the spinal dorsal horn, and how their imbalance disrupts somatosensory processing.

122 Ataxia, causing imbalance, dizziness and falls, is a leading cause of ne

123 tify fSNP-bound proteins and AIDP-Wb (allele-imbalanced DNA pulldown-Western blot) to detect allele-s

124 bone resorption and modulated the Th17/Treg imbalance during experimental periodontitis.

125 bone resorption by modulating the Th17/Treg imbalance during periodontitis.

126 Yet, the drivers and patterns of microbiota imbalance (dysbiosis) in wild animals remain largely une

127 ation, oxidative stress, vasoactive mediator imbalance, dysregulated endocannabinoid and autonomic ne

128 ic-insults to RTECs can cause systemic fluid imbalance, electrolyte abnormalities and metabolic waste

129 ck proteins, minerals and fibres and have an imbalanced energy value, as they are primarily based on

130 Here, we reveal the significant and imbalanced environmental and socio-economic effects of t

131 obesity are assumed to arise from an energy imbalance, evidence has shown that the frequency and tim

132 ust and swim speed, and whether hypothetical imbalances exist in the speed achieved while performing

133 ized that sucrose can introduce a microbiota imbalance favoring caries to a greater degree than other

134 pulation, aggression is predicted by allelic imbalance favoring the supergene allele.

135 diabetes mellitus (GDM) is a hyperglycaemic imbalance first recognized during pregnancy, and affects

136 a cells was originally envisaged as a random imbalance from "noise" in lin-12 expression/activity [6]

137 However, the impact of miRNAs on this imbalance has not been studied systematically.

138 of the findings may be limited by the gender imbalance, high educational attainment, survival bias, a

139 totoxicity in cancer cells by creating redox imbalance; however, the mechanistic basis of KP372-1-ind

140 ed that ZIKV microcephaly is associated with imbalanced immune activation and inflammation.

141 many affected individuals display metabolic imbalances, immune dysregulation, gastrointestinal dysfu

142 imaging studies of excitation and inhibition imbalance in autism.

143 est that obesity may indeed be related to an imbalance in behavioural control as expressed in a pheno

144 The imbalance in carbohydrate/protein content was specially

145 An imbalance in cellular homeostasis occurring as a result

146 called attention to the prevalence of gender imbalance in citations.

147 Methods for quantifying the imbalance in CpG methylation between alleles genome-wide

148 opamine D(1) receptors (D(1)R), producing an imbalance in dopaminergic neurotransmission and cell dea

149 vented sickling and ameliorated globin chain imbalance in erythroid progeny from sickle cell disease

150 processing of its transcript, leading to an imbalance in favor of AapA1 toxin expression.

151 egative consequences, possibly reflecting an imbalance in frontostriatal circuits that encode reward

152 memory retention, which was paralleled by an imbalance in GABA/glutamate presynaptic activity and alt

153 in pG4 UTR sequences, we find robust allelic imbalance in gene expression across diverse tissue conte

154 Disruption or imbalance in homeostasis results in functional disturban

155 At baseline, imbalance in MA rates across ranibizumab arms was eviden

156 vated in Rab23(-/-)sutures with a consequent imbalance in MAPK, Hedgehog signaling and RUNX2 expressi

157 Imbalance in measured maternal obstetrical and sociodemo

158 ronic administration would lead to phosphate imbalance in mice with reduced active intestinal absorpt

159 changes suggest mechanisms for producing an imbalance in muscle function.

160 infarction (T2MI) occurs because of an acute imbalance in myocardial oxygen supply and demand in the

161 h (SRB; ratio of male to female live births) imbalance in parts of the world over the past few decade

162 inally, the fungal infection causes a strong imbalance in plant sugar distribution, ultimately impact

163 y bear significance for alveoli gas exchange imbalance in pneumonia.

164 ppreciated outcome for neutrophil-macrophage imbalance in promoting host susceptibility to acute pyel

165 The resulting imbalance in protein synthesis and degradation is found

166 ith BALF from controls identifies a critical imbalance in RAS represented by decreased expression of

167 ypothesized that weight status relates to an imbalance in reliance on model-based and model-free cont

168 pecificity, leading to excitation/inhibition imbalance in several key regions, namely the medial pref

169 mechanistic insight into an immuno-lipidomic imbalance in severe COVID-19.

170 at loss of acetylcholine leads to a dopamine imbalance in striatal compartments, thereby promoting ha

171 vidence highlights an association between an imbalance in the composition and abundance of bacteria i

172 sk factor for immune-mediated diseases is an imbalance in the gut microbiome.

173 Imbalance in the level of the pyrimidine degradation pro

174 Unexpectedly, we observed that an imbalance in the levels of the lamina-associated polypep

175 rial dysfunction, but triggers a detrimental imbalance in the mitochondrial redox system, which will

176 de adenine dinucleotide (NAD) levels, and an imbalance in the NAD metabolome that includes elevated C

177 ts triggers a state of excitatory-inhibitory imbalance in the PFC that limits its functional capacity

178 axane with optically active anions causes an imbalance in the population of the two enantiomeric coco

179 we evaluated principal causes underlying the imbalance in the quantitative enzyme-product relationshi

180 gy for ammonia oxidizers (AO), leading to an imbalance in the terrestrial nitrogen cycle.

181 In addition, an imbalance in the traffic of the model cargo Cadherin-2 a

182 By assessing the allelic imbalance in the transcriptomes of 19 F1 hybrid lines fr

183 There was a baseline imbalance in tissue eosinophils and high variability bet

184 There was no significant imbalance in tolerability or safety events between dapag

185 We also discuss how an imbalance in vascular activation by leukocytes outside t

186 besity pandemic results from a physiological imbalance in which energy intake chronically exceeds ene

187 nistic interactions of two genetic pathways, imbalance in which may lead to disorders/differences of

188 After adjusting for imbalances in baseline and implementation factors, the i

189 Transient imbalances in excitatory and inhibitory activity may pro

190 ynaptic excitation to inhibition (E/I ratio) imbalances in human brain diseases, is a highly relevant

191 ting for detecting statistically significant imbalances in mean methylation level and methylation ent

192 Third, imbalances in neurotransmitter-positive GCs and an obser

193 t poor genomic maintenance as well as clonal imbalances in normal immune function, making mLOY an att

194 GALE deletion in human cells triggers major imbalances in NSs and dramatic changes in glycolipids an

195 P imbalance between trophic levels but also imbalances in other elements, reflecting complex physiol

196 he home and family, may contribute to gender imbalances in science, technology, engineering and mathe

197 The model revealed quantitative imbalances in TFs' cross-antagonistic relationships that

198 Imbalances in the activity of the D1-expressing direct p

199 he observed associations were not related to imbalances in the distribution of other concomitant type

200 Imbalances in the glutamatergic system, leading to exces

201 gates largely insensitive to stoichiometric imbalances in the inputs, and the modularity of the appr

202 ched to controls (n = 76 825), and remaining imbalances in the number of individuals in each group we

203 Short-distance swimmers may exhibit imbalances in their upper-limbs' thrust (differences bet

204 ntal disorders are associated with different imbalances in these dimensions.

205 ossible therapeutic interventions to correct imbalances in this triune.

206 Imbalances in UPR signaling are implicated in the pathog

207 PERK signaling to both ameliorate pathologic imbalances in UPR signaling implicated in these differen

208 cause respiratory depression and electrolyte imbalances, in the present study we investigated whether

209 ar etiology of illnesses characterized by NS imbalances, including galactosemia and metabolic syndrom

210 tation to IAV-induced inflammation and redox imbalance increased the expression of the pneumococcal c

211 This imbalance induces the data to be highly sparse, preventi

212 that ACDase deficiency leads to sphingolipid imbalance, inflammation, dysmorphic retinal and optic ne

213 Here, we discuss how imbalanced interferon responses may contribute to the pa

214 ateralization of face processing arises from imbalanced intra- and interhemispheric connections.

215 Homeostatic imbalance is caused by a range of pathophysiological mec

216 Importantly, we show that this imbalance is driven largely by the citation practices of

217 Feature selection in class-imbalance learning has gained increasing attention in re

218 ures and control false discoveries for class-imbalance learning.

219 ion methods are lack of skills to handle the imbalanced learning issue inherent in the essential gene

220 same cost-sensitive technique to against the imbalanced learning issue.

221 t-sensitive technique is used to address the imbalanced learning problem when training the deep neura

222 y predicting a central inhibitory/excitatory imbalance linked to RAGE shedding.

223 low rate of survival and the massive genetic imbalance, little research has been aimed at understandi

224 factors that specifically bind in an allele-imbalanced manner to the fSNPs on the FGFR2 locus.

225 Understanding these immune imbalances may facilitate better diagnosis, prevention,

226 ture, suggesting that reciprocal chromosomal imbalances may lead to opposite changes in brain structu

227 e and effective, improving muscle activation imbalance, movement patterns, and alignment.

228 ategies directed at restoring the angiogenic imbalance observed during pre-eclampsia.

229 ena responsible or consequence for the redox imbalance observed in ASD.

230 The imbalance of Abeta production and clearance leads to Abe

231 COVID-19 pathophysiology has been proposed: imbalance of angiotensin converting enzymes (ACE)1 and A

232 s sensitive to local AMPK stimulus, with the imbalance of bidirectional mitochondrial transport resul

233 An imbalance of cellular oxidants and reductants causes red

234 The resulting imbalance of corticolimbic circuit development is a nove

235 an restrict mirotubule length and promote an imbalance of dynein-mediated pulling forces that allows

236 is a complex neurological disease caused by imbalance of excitation and inhibition in the brain.

237 As a result, an imbalance of excitatory-inhibitory synaptic activity eme

238 gy-associated obesity is attributable to the imbalance of fatty acid supply and oxidation.

239 In light of other data supporting a central imbalance of glutamate-glutamine cycling in depression,

240 With increasing evidence suggesting that the imbalance of gut microbiota plays a significant role in

241 ivities, leading to dyserythropoiesis and an imbalance of hematopoietic differentiation.

242 B-12 and folate individually, as well as an imbalance of high folic acid and low vitamin B-12 status

243 L tumors with these mutations had a distinct imbalance of HNRNPH1 isoforms.

244 Disruption of GAD1 results in an imbalance of inhibitory and excitatory neurotransmitters

245 m relationships, we found that the resulting imbalance of medial temporal lobe-prefrontal cortex conn

246 rcome include mistrust by community members, imbalance of power, and unequal sharing of credit.

247 tes CEF to produce ATP to compensate for the imbalance of reducing equivalents.

248 e chronic brain phase, potentially due to an imbalance of regulatory protein levels.

249 opmental progenitors presenting a fixed fate imbalance of self-renewing divisions with an ever-decrea

250 h repressed Orm2 and prevented a detrimental imbalance of SL metabolism.

251 We believe that in the latter cells, an imbalance of spindle-mediated force and the simultaneous

252 nterconnected biological pathways, involving imbalance of the gut microbiome, inflammation, metabolic

253 INPP1 deficiency results in an intracellular imbalance of the inositol polyphosphate metabolism.

254 (MDV) causes deadly lymphoma and induces an imbalance of the lipid metabolism in infected chickens.

255 Network-wide imbalance of the NOTCH pathway was seen in CCA, includin

256 Women with bacterial vaginosis (BV), an imbalance of the vaginal microbiome, are more likely to

257 n environments and lifestyles have led to an imbalance of this evolutionarily ancient process, coinci

258 natural phosphorus (P) scarcity, geographic imbalances of P reserves, and eutrophication.

259 t expression can cause excitatory-inhibitory imbalance often associated with neuropsychiatric disorde

260 sponses to biological cues such as metabolic imbalance or virus infection.

261 Imbalance, or dysbiosis, of the gut microbiome of infant

262 ough VFV protects patients from small muscle imbalances over the lifespan, even enhanced VFV may be i

263 or, nearly all of which harbored allelically imbalanced p53 and/or RAS pathway mutations.

264 ockdown of XIST specifically altered allelic imbalance patterns between X chromosomes.

265 their position as one of defense, and power imbalances place status quo challengers in a defensive p

266 lleles targetable by APA, along with allelic imbalances pointing to LOH, in ~ 24% of tumors.

267 The resultant imbalanced polarization profile can then couple to the o

268 The resulting allelic imbalance profile is critical for determining whether th

269 ent in vestibular mutants, suggesting sensed imbalance promotes coordinated movements.

270 Future studies will determine whether this imbalance represents an early, Abeta-independent pathway

271 Correcting this imbalance requires integrated strategies to achieve incl

272 Mitigating such imbalances requires energy and should impact the efficie

273 bnormalities that are thought to reflect E/I imbalances revealed elevated fE/I and LRTC in ASD childr

274 els that network connectivity and functional imbalances revert to normal levels upon epichaperome inh

275 competition - representing focal effects of imbalanced sex ratios.

276 ns may relate to an overarching system-level imbalance-specifically a disruption in macroscale hierar

277 ast and efficient workflow to analyze highly imbalanced, targeted next-generation sequencing data gen

278 (Genotype-independent Signal Correlation and Imbalance) test(1) to call out 1680 haQTLs (FDR, 10%).

279 An intense inflammatory imbalance that is proportional to the disease severity h

280 nges contribute to the excitatory/inhibitory imbalance that scales up neuronal network activity under

281 activity of this enzyme can produce hormonal imbalances that can be detrimental to sexual and skeleta

282 eric dynamics and cloud effects to radiative imbalance, the satellite-measured radiative response wil

283 acterised by cellular senescence, leading to imbalanced tissue maintenance, cell death and compromise

284 drug target prediction by leveraging a class imbalance-tolerant machine learning framework with a nov

285 either the overall visitation volume or the imbalanced tourist distribution; and (3) the increase of

286 The scale of immune function was imbalanced toward a sensitizing of inflammatory pathways

287 Despite a spatial imbalance towards the most developed regions of the Nort

288 high accuracy when it comes to a smaller or imbalanced training set.

289 ted compounds resulted in the cellular redox imbalance triggering the repair systems and influenced t

290 tion is critical for a healthy blood supply; imbalances underlie hematological diseases.

291 h multiple paths to an excitatory-inhibitory imbalance underlying ASD.

292 mage that can lead to biases such as allelic imbalance, uneven coverage and over representation of C

293 Similar imbalance was not observed in layers 4 or 5 of the neoco

294 findings thus reveal a new mechanism, redox imbalance, which underlies the differential vulnerabilit

295 occurred in the presence of severe metabolic imbalance, while atrioventricular block was largely an i

296 Such imbalance will spatially segregate the two populations a

297 , involvement of GATA1/HSP70 and globin/heme imbalance, with an excess of the toxic free heme leading

298 arization, counteract this tumor-host energy imbalance, with significant results in preclinical model

299 n linked to increased risk of infection, but imbalances within the intestinal microbial community str

300 ease emergence reflects dynamic balances and imbalances, within complex globally distributed ecosyste