ライフサイエンスコーパス: immune function

1 under eCO(2) results in increased endogenous immune function.

2 t sample location to test temporal change in immune function.

3 tions with offspring growth, metabolism, and immune function.

4 rease tumor suppressor function, and enhance immune function.

5 to development, environmental responses and immune function.

6 e of C5aR2 as a powerful regulator of innate immune function.

7 RAS superfamily GTPases required for proper immune function.

8 ess specific features of adaptive and innate immune function.

9 ses BV walls, and that this is important for immune function.

10 at the level of protecting from host innate immune function.

11 ng the compartment with long-term defects in immune function.

12 seases of aging, and its potential impact on immune function.

13 Early life microbiome development trains immune function.

14 r-dependent adipose tissue expandability and immune function.

15 are related cell populations that provide an immune function.

16 tumor cell growth and suppressing antitumor immune function.

17 cell envelope and its impact on host innate immune function.

18 sphoprotein networks known to play a role in immune function.

19 nic microglia-like cells in order to enhance immune function.

20 ic and neural networks, the stress axis, and immune function.

21 1), which encode regulators required for TIR immune function.

22 ffect of chronic cerebritis on cognitive and immune function.

23 and somatic drivers, and support a role for immune function.

24 XFAD mice, many of which are associated with immune function.

25 n characterizing and diagnosing disorders of immune function.

26 remote organs and mucosal and hematopoietic immune function.

27 repair, cell cycle, signal transduction and immune function.

28 ecause they play a role in the regulation of immune function.

29 ated pathways including lysosomal and innate immune function.

30 ur findings provide a link between sleep and immune function.

31 negative breast cancer, several with a known immune function.

32 molecules influencing growth, migration, and immune function.

33 e circadian clock is a critical regulator of immune function.

34 ing tumor reduction while preserving patient immune function.

35 eins associated with NO signaling and innate immune function.

36 esponses to the microbiota and modulate host immune function.

37 platelets and the consequences for platelet immune function.

38 to identify and explain natural variation in immune function.

39 ating this transcription factor critical for immune function.

40 essive, acute stress can temporarily enhance immune function.

41 rforming in vitro studies assessing cellular immune function.

42 and key life-history events that may affect immune function.

43 atures relevant to asthma, inflammation, and immune function.

44 site can affect either treatment efficacy or immune function.

45 hat dLAN has transgenerational influences on immune function.

46 itis (RA) do not reverse underlying aberrant immune function.

47 t Escherichia coli, as a functional assay of immune function.

48 tution, including antigen-dependent adaptive immune function.

49 in after degranulation and reduced cytotoxic immune function.

50 l signaling, and evaluation of the resultant immune function.

51 rs associated with MPS maturation and innate immune function.

52 rily related to glucocorticoid signaling and immune function.

53 xhaustion, and senescence known to influence immune function.

54 genetic variation and stimulatory context on immune function.

55 drugs on primary human cells in relation to immune function.

56 ls maintained body mass despite variation in immune function.

57 specific differences in lactation, diet, and immune function.

58 n-excitable cells and is required for proper immune function.

59 microbiota, and disturbances in mucosal and immune function.

60 ections, likely because of severely impaired immune function.

61 rexpression in myeloid cells increases their immune function.

62 genes implicated in chronic pathologies and immune functions.

63 on of immunothrombi while maintaining innate immune functions.

64 cells of the adult - both cell-types having immune functions.

65 anonically known for its innate and adaptive immune functions.

66 of neurodevelopment, synaptic activity, and immune functions.

67 f several other reflexes regulating discrete immune functions.

68 tum is a visceral adipose tissue with unique immune functions.

69 e complexity of cell behavior in relation to immune functions.

70 of realistic contaminant mixtures on various immune functions.

71 al, metabolic, endocrine, cardiovascular and immune functions.

72 eeding, gastrointestinal (GI) digestive, and immune functions.

73 and core body temperature, oncogenesis, and immune function(3).

74 tion; 5) induces oxidative stress; 6) alters immune function; 7) alters cell signal transduction; 8)

75 kely to vary at spatial scales and influence immune function: (a) parasite pressure, (b) abiotic and

76 The microbiome modulates host immune function across the gastrointestinal tract, perip

77 unique acute and persistent insults to their immune function after CAR-T-cell infusion.

78 iations may modulate HIV vaccine effects and immune function after HIV vaccination.IMPORTANCE By anal

79 une defense, we predict a decrease in innate immune function along a gradient of increasing aridity f

80 s of labour appears to reveal differences in immune function among infants at risk of food allergy.

81 r regulatory locus that likely has a role in immune function and a locus regulating hippocampal long

82 mperature is known to affect many aspects of immune function and alterations in temperature regimes h

83 As knowledge of immune function and appreciation of immunodeficiency has

84 an directly and indirectly affect anti-tumor immune function and cancer cell growth.

85 iated keratinocytes, comprising keratinocyte immune function and cellular structure, was found to be

86 ng the multi-layered processes that underlie immune function and dysfunction, but require a standardi

87 axis coordinates developmental remodelling, immune function and energy allocation in larval amphibia

88 effects in white blood cells that influence immune function and health outcomes.

89 Chronic CMV infection further impairs immune function and is associated with increased mortali

90 n conjunction with ART treatment can restore immune function and may reduce viral reservoirs during c

91 me does seem to affect some pathways such as immune function and metabolism, our data suggest the mic

92 ffects on pregnancy outcomes in women and on immune function and neurodevelopment in children.

93 ssed miRNAs are involved in neuroplasticity, immune function and neurorestoration.

94 However, while the implications of immune function and nutrition on an individual's lifespa

95 coevolved microbiota heavily involved in bee immune function and nutrition.

96 r better understanding of sex differences in immune function and opioid pharmacokinetic and pharmacod

97 have prominent roles in pathways other than immune function and overall the effect sizes were minima

98 f this pathway may have potential to restore immune function and promote viral control or elimination

99 istimed feeding has functional relevance for immune function and provide further evidence for the int

100 Differences in immune function and responses contribute to health- and

101 e the relationship between early life innate immune function and serum vitamin D.

102 d with the condition-dependent expression of immune function and stress response.

103 clude that GIMAP6 plays a role in modulating immune function and that it does this by controlling cel

104 or for 5 to 6 weeks and evaluated intestinal immune function and the composition of the fecal bacteri

105 s and its implication in the pathogenesis of immune function and the development of CF lung disease.M

106 This review examines known measures of immune function and the immunologic effects of common im

107 lation-based networks that are implicated in immune function and tumor development pathways.

108 has multiple functions related to apoptosis, immune function and various cancers.

109 the impact of these environmental factors on immune function and, when known, on alloimmune function,

110 d in brain development, synaptic plasticity, immune function and/or schizophrenia, showing some conve

111 he metaexposome in the context of early-life immune functioning and describe how various aspects of a

112 NK cells regulate immune functions and are modulated by killer cell immuno

113 sure to high temperatures is known to impair immune functions and disease resistance of poultry.

114 E STATEMENT Progranulin regulates neuron and immune functions and is implicated in aging.

115 he innate immune response affects downstream immune functions and, ultimately, the outcome of infecti

116 r in their activation state, contribution to immune function, and capacity to proliferate in vivo.

117 T cell phenotype, immune function, and CLL cell immunosuppressive capacity

118 in gastrointestinal microbiota, mucosal and immune function, and CNS processing.

119 Lymph nodes (LN) are crucial for immune function, and comprise an important interface bet

120 and ion homeostasis, cytokine signaling and immune function, and debris engulfment contributions tha

121 Vitamin D has an integral role in proper immune function, and deficiency is common among kidney t

122 ghlight recent work linking social behavior, immune function, and dopaminergic signaling in adolescen

123 ta can modulate gastrointestinal physiology, immune function, and even behavior.

124 y beneficial effects on cellular metabolism, immune function, and gene transcription involved in inna

125 s and play an important role in development, immune function, and human disease.

126 dosing to attain viral suppression, restore immune function, and improve quality of life.

127 immunoproteasome, like other aspects of host immune function, and indicate that immunoproteasome acti

128 such as cancer, marked hyperphagia, impaired immune function, and inflammation.

129 ly has been studied extensively for roles in immune function, and our results identify a novel role f

130 ssion of gene sets associated with glial and immune function, and reduced expression of gene sets ass

131 trations and malaria infection as indices of immune function, and telomere lengths as an overall meas

132 They influence infant neurodevelopment and immune function, and they provide ~50% of milk's energy

133 rate age-related multi-morbidity by boosting immune function, and we consider whether physical activi

134 a composition in the infants' body and early immune function, and whether these contribute to the lat

135 the largest organ in the body with important immune functions, and accumulation of drug delivery syst

136 dipose tissue (VAT), a tissue with important immune functions; and (ii) individuals with poor fetal n

137 Further, we propose that sex differences in immune function are mediated, at least in part, by the e

138 s of the circadian clock, but its effects on immune function are unknown.

139 Concurrently, critical macrophage immune functions are diminished.

140 To walk this line, immune functions are grossly compartmentalized by innate

141 to regulate stress, energy homeostasis, and immune functions are reported to be killed by developmen

142 an present for port placement with depressed immune function as a result of their treatment or diseas

143 Corticosterone treatments affected immune function, as both chronic and acute exposure supp

144 n host physiology, regulating metabolism and immune function, as well as complex host behaviors.

145 ing neurotransmission, neurodevelopment, and immune function, as well as differential miRNA expressio

146 okine/cytokine activity and inflammatory and immune functions associated with carcinogenesis.

147 es that can selectively leverage the humoral immune functions, beyond binding and neutralization, res

148 e tested how diet composition affects innate immune function, body mass and moult separately and in c

149 Exploring the correlations between immune function, body mass and moult, showed that an inc

150 causal effect of diet composition on innate immune function, body mass and moult: bulbuls were in a

151 In Nb, PAD4 demonstrated no detectable immune functions, but TNL-mediated resistance responses

152 ata on detailed patterns of baseline ART and immune function by GBD region, reproductive aging among

153 odels suggest that low social status affects immune function by increasing inflammation and compromis

154 IgG antibodies mediate a diversity of immune functions by coupling of antigen specificity thro

155 y the JC virus and is typically fatal unless immune function can be restored.

156 glycolysis and ATP production could improve immune function, counteracting LA suppressive effects in

157 ng of how the amount of tonic signal impacts immune function, describing novel tools that have moved

158 23) is often elevated in CKD, and may impair immune function directly or indirectly through proinflam

159 In this tropical system, innate immune function does not decrease with increasing aridit

160 ptic plasticity, glial cell development) and immune functions (e.g., immune system activation, leukoc

161 lloenzymes, in addition to playing a role in immune function, endocrine function, hematopoiesis, and

162 e development, bone synthesis, reproduction, immune function, energy metabolism, and cell signaling,

163 gest that socioeconomic conditions influence immune function, growth and health status.

164 tween a metabolite known to be important for immune function-GSH-and the diffusion extracellular FW m

165 these cells operate, extrapolation to human immune function has remained an open question.

166 field, alterations in commensal bacteria and immune function have been implicated in behavioral defic

167 Immune function, height and resource accumulation compri

168 For their immune function, human NK cells rely largely on five dif

169 increased expression of genes with important immune functions (i.e., GAS6, ALOX15B, FCGR2B, LAIR1).

170 kynurenine pathway (KP) regulates macrophage immune function in aging and inflammation.

171 sturbance of the link between metabolism and immune function in CD8 + PD-1 + T cells in T2D was prove

172 rowth, bone formation, neurodevelopment, and immune function in children with MAM.

173 ce of exacerbations, little understanding of immune function in COPD exacerbations exists.

174 cytokine response is commonly used to assess immune function in critically ill patients.

175 enetic and environmental factors influencing immune function in different environments may provide in

176 (MSCs) can stimulate angiogenesis and modify immune function in experimental RVD.

177 ing role of biomaterials as tools to dissect immune function in fundamental and translational context

178 to decode the genetic circuits that control immune function in health and disease.

179 To date, there have been few studies of immune function in healthy older people in sub-Saharan A

180 clusion that suppression of PD effluent cell immune function in human subjects by standard PD fluid i

181 hanism by which helminth infection modulates immune function in LTBI.

182 Our understanding of the deterioration in immune function in old age-immunosenescence-derives prin

183 prevent T cell suppression and restore host immune function in sepsis.

184 ) that plays an important role in regulating immune function in T cells.

185 ence suggests that gut microbiota influences immune function in the brain and may play a role in neur

186 on between neonicotinoid exposure and innate immune function in the bumblebee Bombus impatiens, which

187 provide additional evidence for the role of immune function in the etiology of DLBCL, the most commo

188 Assays which measure immune function in the immunosuppressed transplant recip

189 eview the current understanding of tuft cell immune function in the intestines, airways, and thymus.

190 dy, the impact of tumor secreted exosomes on immune function in the tumor environment was investigate

191 w that female insects (bed bugs) up-regulate immune function in their copulatory organ in anticipatio

192 story ecotypes, which are known to differ in immune function in their native habitats, raised under c

193 Our study highlights the role of innate immune function in thymic regeneration and restoration o

194 ficity and their impact on antibody-mediated immune function in vitro The impact of vFcgammaRs on HCM

195 This study assessed immune functions in fourteen crewmembers.

196 be a valuable resource for dissecting innate immune functions in health and disease.

197 e interactions between antibodies and innate immune functions in humans.

198 and progression involve activation of innate immune functions in microglia, which are brain-resident

199 er cell cycle inhibitors to modulate various immune functions in support of effective antitumour immu

200 expression of genes associated with various immune functions in these cells from VL patients and com

201 r metabolic pathways that subsequently alter immune function, in a process called immunometabolism.

202 eported to be associated with alterations in immune function, in particular immune hyporesponsiveness

203 eplicable gene networks enriched for diverse immune functions including cytotoxicity, viral response,

204 ment of DCs in vitro caused an impairment in immune functions including differentiation, maturation,

205 a infection has been associated with altered immune function, including hyporesponsiveness.

206 IgG Abs are crucial for various immune functions, including neutralization, phagocytosis

207 ry to frequent antimicrobial use, suppressed immune function, increased exposure to healthcare settin

208 elating to adipose dysfunction and fibrosis, immune function, inflammation, and gastrointestinal inte

209 dies linking clonal hematopoiesis to altered immune function, inflammation, and nonmalignant diseases

210 e of "self" versus "nonself" to one in which immune function is critical for homeostasis of organs th

211 ampen B-cell activation, and restore overall immune function is crucial for preventing non-Hodgkin ly

212 Yet, variation in immune function is largely attributed to energetic trade

213 food antigens on intestinal homeostasis and immune function is poorly understood.

214 Immunosenescence, an age-related decline in immune function, is a major contributor to morbidity and

215 o an immune challenge during puberty affects immune function later in life, which could permanently a

216 nance as well as clonal imbalances in normal immune function, making mLOY an attractive candidate mar

217 The best measures of integrated immune function may be quantitative viral loads to asses

218 risk factors that, in addition to modulating immune function, may also converge to act on the vascula

219 se proteins (APPs), key components of innate immune function, measured in neonatal dried blood spots.

220 nclude proliferation, development, toxicity, immune function, metabolism and detoxification.

221 oral factors within a location may influence immune function more strongly than spatial variation in

222 ips were observed between cortisol level and immune function, nor between family income and height.

223 Together, our results establish that HVEM immune function, not binding to gD, mediates establishme

224 Here, we show that HVEM immune function, not its ability to bind gD, is required

225 gen species, closely mimicking the defective immune functions observed in beta-thalassemia patients.

226 Cactin in the mammalian immune response, the immune function of Cactin in insects has not been descri

227 By leveraging this innate immune function of erythrocytes, we developed erythrocyt

228 However, the age-related changes in the immune function of human skin are unclear.

229 Our data suggest that the immune function of HVEM plays an important role in the H

230 The adaptive immune function of lymph nodes is dependent on constant

231 These data indicate an intrinsic, non-immune function of PD-L1, and suggest the potential for

232 The innate immune function of the lung mucosal barrier is dependent

233 risingly, we show in this study that certain immune functions of CD8(+) T cells are enhanced in the a

234 ate the interplay of wholesome sleep and the immune functions of circulating monocytes and T cells in

235 regulates DC maturation and other important immune functions of DCs.

236 The immune functions of epithelia-resident dendritic cells a

237 lycosylation is essential to trafficking and immune functions of human neutrophils.

238 tyrosine kinase activity of EGFR and innate immune functions of STING and suggest new experimental a

239 tional T cells, much less is known about the immune functions of unconventional T cells and their rol

240 0E, halofenozide does not influence cellular immune function or AMP production.

241 enes encoding protein products that regulate immune function or cell adhesion and tumor cell metastas

242 predicting effects of climate variability on immune function or disease risk.

243 genes, including several encoding heightened immune-function or antimicrobial activities.

244 essed in microglial cells, known to regulate immune functions, or both can cause, or alter risk for,

245 and exit the circulation to carry out innate immune functions, or undergo rapid apoptosis and macroph

246 Eczema, wheeze, and immune function outcomes were assessed at 6 months of ag

247 utative mechanisms by which LAP may regulate immune function, perhaps through the metabolic reprogram

248 e of sustenance: a tissue integral to proper immune function, pesticide detoxification, overwinter su

249 However, effects on intestinal type 2 immune function remain unclear.

250 apidly diversified in teleost fish but their immune functions remain unclear.

251 lay between feeding behaviour, infection and immune function remains poorly understood.

252 ecrosis of the jaw involves disruption of DC immune functions required to clear bacterial infection a

253 Although their physiological and detrimental immune functions seem to depend on the anatomical compar

254 y associated with lipid metabolism, but with immune function, signalling and transcriptional regulati

255 reduced larval growth and survival, impaired immune function, skewed sex ratios, ovarian atresia, red

256 tained several genes with known or predicted immune functions, some differentially expressed.

257 tion of AD risk genes associated with innate immune functions suggest that neuroinflammation has a pr

258 An individual's immune function, susceptibility to infection, and respon

259 Brain ischemia inhibits immune function systemically, with resulting infectious

260 arboring genes that encode proteins of known immune function that alter risk of developing Alzheimer'

261 N has transgenerational effects on endocrine-immune function that may be mediated by global alteratio

262 portant insights into THC's acute effects on immune function that may have important medical implicat

263 ved an enrichment of pathways related to the immune function that reflects an increase towards positi

264 t for stratification in the establishment of immune functions that determine efficient seeding of per

265 fy a large surface essential for EDS1-SAG101 immune functions that extends from the N-terminal lipase

266 ral pathogens, antibodies mediate additional immune functions that may have both protective and patho

267 and implicated in leukocyte inflammatory and immune functions, the roles of alphaXbeta2 remain largel

268 ay decrease parasite performance or increase immune function, thereby reducing infection risk or the

269 Therapies that optimize immune function therefore have the potential to improve

270 Beyond classical immune functions, they have been shown to be important f

271 s an immune checkpoint protein that inhibits immune function through its binding of the programmed ce

272 D73 has been implicated in the inhibition of immune function through overproduction of adenosine.

273 CD8+ T cells may be vital for altering host immune functions through increasing the accessibility of

274 mportant intestinal epithelial secretory and immune functions through its actions on epithelial musca

275 e varies with precipitation, we might expect immune function to be higher in the wet season due to in

276 ng the microbiome in early life may modulate immune function to confer protection.

277 nc supplementation is commonly used to boost immune function to prevent infectious diseases in at-ris

278 ptors, transporters, and other proteins with immune functions) to or from the PM via small, membrane-

279 the tumor microenvironment (TME), suppresses immune function via inhibition of T cell and NK cell act

280 al dysbiosis within the gut, altered mucosal immune function, visceral hypersensitivity, and abnormal

281 rition-sensitive trade-off between visceral (immune-function) vs. subcutaneous (body shape) adiposity

282 y mass and moult, showed that an increase in immune function was associated with a decrease in body m

283 The scale of immune function was imbalanced toward a sensitizing of i

284 Improvement of immune function was shown by normalisation of in-vitro T

285 oxygenase 1 (HO-1), a potential modulator of immune function, was increased in whole blood from beta-

286 Consistent with an impact of EBNA3A on immune function, we found that the expression of CLEC2D,

287 marrow hematopoiesis is essential for proper immune function, we hypothesize that SCI disrupts bone m

288 ourea (ENU)-induced mutant mice for aberrant immune function, we identified mice with a syndromic dis

289 lly beneficial for enhancer architecture and immune functions were particularly frequently incorporat

290 Astrocytes perform classical innate immune functions, which contradict the current paradigm

291 cells into CD11c-positive DCs with aberrant immune functions while retaining the capability of proin

292 okine signaling and plays important roles in immune function, while abnormal JAK1 activity has been l

293 dicine that can take advantage of the body's immune functions will increasingly become clinically rel

294 The improved immune function with XPro1595 correlates with less norad

295 stigate the interplay of innate and adaptive immune functions with chronic inflammation, anemia, and

296 cuss therapeutic strategies that can recover immune function, with a particular emphasis on approache

297 The immune function within the tumor microenvironment has be

298 athways regulate many aspects of metabolism, immune function, wound repair, and protection of multipl

299 Interferon-gamma (IFNG) augments immune function yet promotes T cell exhaustion through P

300 PD-L1 interaction to enhance T cell-mediated immune function, yet the effectiveness of anti-PD-L1/PD-