ライフサイエンスコーパス: immunodominant

1 scFv epitope, further suggesting that it is immunodominant.

2 both O-antigen modifications were generally immunodominant.

3 535 and 673, indicating that this region is immunodominant.

4 crystal structure of HLA-DR1 presenting the immunodominant 20-mer peptide 5T4(111-130), combined wit

5 ide and show that only ~35% individuals have immunodominant A68/NP(145)(+)CD8(+) T cell responses.

6 Flagellin is an immunodominant Ag in Crohn disease, with many patients s

7 tivity and area under the curve (AUC) to the immunodominant allergen Ara h 2 correlate with clinical

8 Allergenic extracts that have multiple immunodominant allergenic proteins are standardized with

9 Variable patterns of sensitization with no immunodominant allergens were found in both groups.

10 ogenic T cell response is directed toward an immunodominant alpha-gliadin-derived peptide (DQ8-glia-a

11 Glucose monomycolate was immunodominant among lipid Ags tested, and polyfunctiona

12 press early secretory antigen 6 (ESAT-6), an immunodominant and diagnostic antigen from Mycobacterium

13 ed two core regions overlapping the two most immunodominant and frequently studied CD4 T cell targets

14 we investigated T-cell responses to the two immunodominant and highly homologous HLA-DQ2.5-restricte

15 The receptor-binding domain (RBD) is immunodominant and the target of 90% of the neutralizing

16 Nucleoprotein (N) is an immunodominant antigen in many enveloped virus infection

17 lymphocyte responses against an independent immunodominant antigen in mice, indicating orchestration

18 n side chain of the lipopolysaccharide is an immunodominant antigen, can define host-pathogen interac

19 t cell adhesion and invasion, and is a major immunodominant antigen.

20 G extract or a pool of previously identified immunodominant antigenic regions.

21 These immunodominant antigenic sites are the main targets of n

22 Antibody diversity analysis revealed immunodominant antigenic sites in the N- and C-termini o

23 the hemagglutinin head domain to shield the immunodominant antigenic sites.

24 enhanced T cell immunity to nine of fifteen immunodominant antigens analysed including AhpC (BPSL209

25 S-CoV-2 spike and nucleocapsid antigens, two immunodominant antigens implicated in protective immunit

26 mice and humans, demonstrating flagellins as immunodominant antigens in the intestines.

27 The immunodominant antigens that elicit the protective antib

28 ble prolamins that was achieved choosing the immunodominant apolar peptide from alpha2-gliadin as a t

29 arasite invasion in vitro Neither protein is immunodominant, as both proteins react only marginally w

30 T cell epitopes were genetically fused to an immunodominant B cell epitope derived from the N-termina

31 The identified immunodominant B cell epitopes provide a better understa

32 Ten immunodominant B cell epitopes were identified: CbpD-pep

33 The identification of immunodominant B cell epitopes within surface pneumococc

34 Immunodominant B-epitopes were mainly located on the sur

35 s has been made to identify and characterize immunodominant B. microti antigens for diagnostic and va

36 Thirty of the most immunodominant B. microti antigens were expressed as rec

37 Our studies have enhanced the repertoire of immunodominant B. microti antigens, and assigned potenti

38 , and evolutionary relationships of the most immunodominant B. microti antigens.

39 , which demonstrated that the VP2 epitope is immunodominant between EV71 and CA16.

40 ctively dampen immune responses to undesired immunodominant bridging sheet determinants.

41 ng a therapeutic antibody, we employed a non-immunodominant, but functionally relevant, epitope in do

42 s in the human TCR repertoire targeted at an immunodominant, but highly mutable, HLA-B*0801-restricte

43 nd for multiple HLA targets, considering the immunodominant, but not the sum, of antibodies MFI.

44 01-associated viral polymorphisms within the immunodominant C clade Gag epitope RMTSPVSI (here, RI8;

45 The immunodominant CD4 T-cell antigens included both long pr

46 comprised of protein immunogens fused to an immunodominant CD4(+) T cell epitope of the secreted Ag

47 transgenic mice with a mixture of these two immunodominant CD4(+) T cell epitopes induced a robust a

48 utoimmune renal disorder characterized by an immunodominant CD4(+) T-cell self-epitope derived from t

49 driven by the Myc oncogene and expresses an immunodominant CD8 T cell epitope from MHV-68.

50 ced neutralizing Abs but contains conserved, immunodominant CD8 T cell epitopes.

51 We characterized two immunodominant CD8 T cell populations generated in respo

52 LCMV infection (7 of 36) developed a robust immunodominant CD8 T cell response apparently cross-reac

53 full length of 21-hydroxylase, we identified immunodominant CD8(+) and CD4(+) T cell responses in a l

54 rminal domain contains an epitope that is an immunodominant CD8(+) T cell antigen during primary infe

55 We identified immunodominant CD8(+) T cell epitopes from IBVs that wer

56 rat identified mutations in both identified immunodominant CD8(+) T-cell epitopes.

57 The median MFI of the immunodominant class I or II DSA in the peak or day 0 se

58 eling of the T-cell receptor repertoire with immunodominant clones and serum autoantibodies reactive

59 ecause subdominant TCD8 are more likely than immunodominant clones to escape tolerance mechanisms and

60 xvirus (modified vaccinia Ankara) expressing immunodominant CMV antigens.

61 g T cell receptors (TCRs) that recognize the immunodominant CMV epitope NLVPMVATV (NLV).

62 ified a human TCR with high affinity for the immunodominant CMV peptide and offers a new strategy to

63 mune response predominantly directed against immunodominant conserved T cell epitopes.

64 The use of a soy-peptide-containing an immunodominant cross-reactive T-epitope, along with a si

65 tudy, we characterized the importance of the immunodominant CSP-derived epitope SYIPSAEKI of Plasmodi

66 mediated by CD8(+) T cells specific for the immunodominant CSP-derived epitope.

67 d Triplex by constructing an rMVA encoding 3 immunodominant cytomegalovirus (CMV) antigens, which sti

68 ited a strong CD8 T-cell response toward the immunodominant D(b)-restricted TMEV-derived peptide, VP2

69 op region of gp41 is also known as principal immunodominant domain (PID) because of its high immunoge

70 disulfide loop region (DLR) of the principal immunodominant domain of gp41, recognized by the well-kn

71 pecific CD4(+) T cell responses targeting an immunodominant DRB1*11-Gag41 complex and HIV control, hi

72 ith the diagnosis of active sAMR were MFI of immunodominant DSA > 4000, MFI of the sum of DSA > 6300,

73 ith the diagnosis of active sAMR were MFI of immunodominant DSA >4000, MFI of the sum of DSA >6300, a

74 The MFI of the immunodominant DSA (iDSA, the DSA with the highest MFI l

75 Although mean fluorescence intensity of the immunodominant DSA diagnosed ABMR (AUC=0.75; 95% CI, 0.6

76 ; P<0.001), combining urinary CXCL10:Cr with immunodominant DSA levels improved the diagnosis of ABMR

77 antibodies are better evaluated through the immunodominant DSA MFI than through the sum of DSA MFI.

78 Multivariate analysis revealed that immunodominant DSA reduction > 50% at 14 days was associ

79 Immunodominant DSA reduction at 14 days differed signifi

80 We show that CD4(+) T cells recognizing immunodominant Dsg3 epitopes in the context of the PV-as

81 9, and 638 to 651, instead of the well-known immunodominant E2 hypervariable region 1 (HVR1).

82 Among these, we identified two immunodominant effector memory CD4(+) T(EM) cell epitope

83 ve novel MHC II tetramers were made using an immunodominant EFYQSTCSAVSKGYL (F-EFY) epitope restricte

84 hat memory CD8 T cells specific for a single immunodominant epitope (S436 or S525) substantially prot

85 ur-TCR-Tg]) expressing a TCR recognizing the immunodominant epitope (Sur20-28) of murine survivin dur

86 essive effector memory CTLs specific for the immunodominant epitope 40-48 of myelin oligodendrocyte g

87 DC increased cross-presentation of E75, the immunodominant epitope derived from the HER2 protein, an

88 7BL/6 mouse, CD8(+) T cells specific for the immunodominant epitope from glycoprotein B maintain func

89 These results indicate that the immunodominant epitope in PLA2R is exclusively located i

90 s optica (NMO) patients, which recognize the immunodominant epitope of aquaporin-4, exhibit Th17 pola

91 y using a human T-cell line specific for the immunodominant epitope of Bet v 1 and in vivo in an adju

92 Specifically, an immunodominant epitope of EV71 that maps to the virus ca

93 In addition, 26D1 epitope is immunodominant epitope recognized by both antibodies eli

94 Here, we identified the immunodominant epitope region in PLA2R by probing isolat

95 elated with overall sequence homology, and 2 immunodominant epitope regions of Phl p 12 were identifi

96 e was shifted from the previously identified immunodominant epitope to a novel epitope when the antig

97 iviral CD8 T cell responses against the TMEV immunodominant epitope VP2(121-130), with functional imp

98 57BL/6 mice, which are unable to present the immunodominant epitope, CSP-based vaccines did not confe

99 T-cell response directed against the single immunodominant epitope, we identify the sequence feature

100 a vaccine expressing the same Ag without its immunodominant epitope.

101 V-1 peptides detected revealed an additional immunodominant epitope.

102 We show that ANT1 encompasses multiple immunodominant epitopes (namely, ANT1 21-40, ANT1 31-50,

103 Progress in defining the immunodominant epitopes and how neutralizing antibodies

104 Immunodominant epitopes are few selected epitopes from c

105 Autoantigen-derived immunodominant epitopes are resistant to digestion by ca

106 rove our ability to elicit antibodies to non-immunodominant epitopes by vaccination.

107 nduced CD8(+) T-cell responses against three immunodominant epitopes can increase the incidence of el

108 and transient exposure of non-neutralizing, immunodominant epitopes could hinder the induction of br

109 or memory CD4(+) T(EM) cells specific to two immunodominant epitopes derived from the HSV-1 tegument

110 vant-free mix of three peptides that include immunodominant epitopes for gluten-specific CD4-positive

111 Unlike most pathogens, many of the immunodominant epitopes from Mycobacterium tuberculosis

112 s on and responds to very few representative immunodominant epitopes from pathogenic insults.

113 Immunodominant epitopes highly conserved across genotype

114 ents termed nanoallergens, we identified two immunodominant epitopes in peanuts that were common in a

115 lass I (MHC-I) molecule Mamu-B*08 that binds immunodominant epitopes in Vif and Nef.

116 g without limiting virus viability, and also immunodominant epitopes located in variable regions.

117 compared with uncomplexed trimers.IMPORTANCE Immunodominant epitopes may suppress immune responses to

118 CD8(+) T cell immunodominant epitopes of alpha-NAC were mapped by appl

119 cted autoreactive CD4(+) T cells recognizing immunodominant epitopes of Dsg3 initiate the production

120 ead consistent with periodic turnover of the immunodominant epitopes of PfEMP1 associated with severe

121 N specifically inhibited the response to two immunodominant epitopes that are known to be dependent o

122 at Cas9 protein can be modified to eliminate immunodominant epitopes through targeted mutation while

123 We identified four immunodominant epitopes using synthetic peptides, and ma

124 T-cell IFN-gamma immunity to OprF and its immunodominant epitopes was characterized.

125 human leukocyte antigen (HLA) restriction of immunodominant epitopes were defined using HLA class II

126 Immunodominant epitopes were the most efficacious in lon

127 e mechanisms that determine the selection of immunodominant epitopes within complex protein antigens

128 We identified novel CD4- and CD8-restricted immunodominant epitopes within NS6 and VP1 antigens.

129 n, and neuraminidase can easily mutate their immunodominant epitopes without impacting fitness.

130 on in a Japanese cohort, they included three immunodominant epitopes, emphasizing the contribution of

131 K288S/Y176F, a variant mutated in one of the immunodominant epitopes, showed reduced antigenicity.

132 Two immunodominant epitopes-one to precursor membrane protei

133 can distort the capture of the physiological immunodominant epitopes.

134 he size of the CD8(+) T cell response to two immunodominant epitopes.

135 ic mice that are centrally tolerant to these immunodominant epitopes.

136 y landscape in favor of MHC I complexes with immunodominant epitopes.

137 class II molecules and included most of the immunodominant epitopes.

138 ssed HLA class II molecules and knowledge of immunodominant epitopes.

139 le antigens may be biased towards conserved, immunodominant epitopes.

140 is skewing of antibody responses to variable immunodominant epitopes.

141 dominant, conserved lateral patch had become immunodominant for individuals with B-cell memory imprin

142 m of regulation, as well as whether a single immunodominant form of synthetic sulfatide can treat ong

143 abbit IgG against the murine homologs of two immunodominant fragments in adult C57BL/6 mice (mLAMalph

144 ursor membrane protein and do not expose the immunodominant fusion loop epitope.

145 Antibodies to linear epitopes, including the immunodominant fusion-loop epitope, were able to bind ZI

146 ere, we defined the MHC class II alleles for immunodominant Gag CD4(+) T cell epitopes in clade C vir

147 ween HIV-specific CD4(+) T cell targeting of immunodominant Gag epitopes and immune control, particul

148 employed MHC class II tetramers designed to immunodominant Gag epitopes and used them to characteriz

149 ctedly higher functional avidity than is the immunodominant Gag-recognizing counterpart.

150 Importantly, targeting of the immunodominant Gag41 peptide in the context of HLA class

151 developed recombinant HSV-1 with the native immunodominant gB epitope disrupted but then expressed e

152 nt viral promoters driving expression of the immunodominant gB epitope.

153 ut strain specific due to their focus on the immunodominant globular head domain of the hemagglutinin

154 neutralizing antibodies against the variable immunodominant globular head domain of the viral hemaggl

155 tide-MHC (pMHC) complex of HLA-DQ2.5 and the immunodominant gluten epitope DQ2.5-glia-alpha1a using p

156 ndividuals do not mount a T cell response to immunodominant gluten epitopes of CD.

157 have used tetramers of HLA-DQ2.5 bound with immunodominant gluten epitopes to explore whether HLA-DQ

158 s the most abundant cell type presenting the immunodominant gluten peptide DQ2.5-glia-alpha1a in the

159 receptor (TCR) repertoires directed to some immunodominant gluten peptides have previously been desc

160 ded that ICs based on MAbs that bound to the immunodominant glycan hole epitope likely diverted antib

161 We conclude that even for the immunodominant glycan hole shared between BG505 and B41,

162 Thus, even for the immunodominant glycan hole shared between BG505 and B41,

163 overcome this problem, we attempted to mask immunodominant glycan holes by immunizing rabbits with I

164 ocompatibility complex multimers against the immunodominant H4, H7, H13, H28, and H60 minor Ags.

165 agglutinin consists of a highly variable and immunodominant head domain and a more conserved but immu

166 ilized-stem (HA-SS) immunogens that lack the immunodominant head domain.

167 The latter included 2 previously reported immunodominant HIV-1 epitopes, and analysis of T cell re

168 eome (6030 proteins) and identified the most immunodominant HLA class I, HLA class II and B- cell epi

169 cts against HIV disease progression, but the immunodominant HLA-B*14-restricted anti-HIV response is

170 se TCR repertoire enables recognition of the immunodominant HLA-DQ2.2-glut-L1 epitope.

171 allergen, Art v 1, contains only one single, immunodominant, HLA-DR1-restricted epitope (Art v 125-36

172 We have defined the immunodominant, HLA-restricted T-cell epitopes of OprF.

173 Our findings identify immunodominant human norovirus T-cell epitopes and demon

174 DR transgenic mice with a mixture of the two immunodominant human VP11/12 CD4(+) T(EM) cell epitopes,

175 eferentially' activated and mobilized within immunodominant human-leukocyte-antigen-(HLA)-A*11:01-res

176 ar disparity in the abundance of the two key immunodominant IAV antigens, wherein direct infection dr

177 g T-cell receptors (TCRs) that recognize the immunodominant IAV epitope GILGFVFTL (GIL).

178 omologous (C.1086) V1V2, V2 HS, V3, and gp41 immunodominant (ID) proteins.

179 tive N-terminal region was identified as the immunodominant IgA epitope.

180 The AD-3-immunodominant IgG response following human gB/MF59 vacc

181 One region in the wing domain of NS1 was immunodominant in both mouse vaccination and human infec

182 wever, HA antigenic site B, which has become immunodominant in recent human H3N2 influenza viruses, i

183 In parallel, CD8(+) T cell responses against immunodominant influenza epitopes were also measured.

184 rst time, to our knowledge, that the HLA-B27 immunodominant influenza nucleoprotein (NP) 383-391 epit

185 HC individuals after activation with pooled immunodominant islet peptides.

186 The observations that immunodominant ligands can be found at lower levels and

187 identified phosphatidylglycerol (PG) as the immunodominant lipid antigen.

188 Moreover, the functional avidities of the immunodominant M1(58-66)/HLA-A*02:01-specific T cells we

189 Deep viral sequencing of the immunodominant Mamu-B*017:01-restricted Nef165-173IW9 ep

190 e recently shown that vaccination with three immunodominant Mamu-B*08-restricted epitopes (Vif RL8, V

191 ll responses in these animals are focused on immunodominant Mamu-B*08-restricted SIV epitopes in Vif

192 Three known immunodominant membrane proteins, i.e., two 28-kDa outer

193 death-1 (PD-1), but surprisingly, while the immunodominant memory response appeared to be functional

194 lium-specific serum antibodies targeting the immunodominant MgpB and MgpC proteins appeared within 1

195 ation to generate antigenic diversity in the immunodominant MgpB and MgpC proteins.

196 ue within an LC3-interacting region motif of immunodominant MOG peptides abrogated their degradation.

197 conversion of destructive processing of the immunodominant MOG40-48 epitope into productive processi

198 synthetic compounds were employed to uncover immunodominant moieties of ECA.

199 nopropyl)-carbodiimide (ECDI), to couple the immunodominant MPO peptide (MPO(409-428)) or a control o

200 ng apoptotic splenocytes conjugated with the immunodominant MPO peptide suppresses anti-MPO GN by ind

201 phylococcus aureus peptide, homologous to an immunodominant MPO T-cell epitope (MPO(409-428)), can in

202 secretory antigenic target-6 (ESAT-6) is an immunodominant Mycobacterium tuberculosis (M.tb) antigen

203 s B cells to protect a proteolysis-sensitive immunodominant myelin oligodendrocyte glycoprotein (MOG)

204 s more severe disease, we show here that the immunodominant myelin proteolipid protein epitope (PLP(1

205 , comprising a polyrhamnose backbone with an immunodominant N-acetylglucosamine (GlcNAc) side chain,

206 lerance induced by nasal insufflation of the immunodominant nephritogenic MPO peptide (MPO409-428) to

207 existing immunity by constantly altering the immunodominant neutralizing antibody epitopes (antigenic

208 region of the envelope protein is likely an immunodominant, neutralizing epitope.IMPORTANCE Zika vir

209 The monoclonal antibody m102.4 binds to the immunodominant NiV receptor-binding glycoprotein (GP), a

210 ibody epitopes but limit the presentation of immunodominant non-NAb epitopes that might induce off-ta

211 Ab mapping demonstrated targeting of immunodominant non-neutralizing epitopes by conventional

212 Viral subunit vaccines often contain immunodominant non-neutralizing epitopes that divert hos

213 mutant EDIII was due to the shielding of the immunodominant nonneutralizing epitope surrounding resid

214 bunit vaccines is their artificially exposed immunodominant nonneutralizing epitopes, which can be ov

215 es with particular epitopes eliciting either immunodominant or subdominant responses after viral chal

216 mpared with mice that received an irrelevant immunodominant ovalbumin (OVA) peptide, OVA323-339, mice

217 Our results show that using an immunodominant peptide (I10) or the complete GALNS enzym

218 One remarkably promiscuous immunodominant peptide (P9) could be presented by divers

219 e whether DEC205(+) DC targeting of a single immunodominant peptide derived from human cartilage prot

220 y which MHC class I (MHC I) molecules sample immunodominant peptide epitopes, however, remains poorly

221 icated that the I-A(b) binding region of the immunodominant peptide of MOG is susceptible to cleavage

222 An immunodominant peptide of recoverin, AG-16, was capable

223 tic cells, to process and present the I-A(b)-immunodominant peptide of the autoantigen myelin oligode

224 els depend on T cells restricted to a single immunodominant peptide of the immunizing Ag, which does

225 As HLA-DM activity directly favors immunodominant peptide presentation, polymorphisms in HL

226 nsion, with implications for beta-selection, immunodominant peptide recognition, and germ line-encode

227 T cell lines were specific for 15 immunodominant peptides and derived preferentially from

228 The recognized peptides differed from the immunodominant peptides and were part of the best promis

229 ivity by EBV led to total degradation of the immunodominant peptides MOG35-55 and MOG1-20 Inhibition

230 heterodimers, we bioinformatically predicted immunodominant peptides of topoisomerase 1, fibrillarin,

231 s were primarily directed against just a few immunodominant peptides that were readily detected by ma

232 igen (HLA)-A2 and bioinformatics to identify immunodominant peptides.

233 back, potentially via epitope masking of the immunodominant PfCSP repeat region.

234 otein in human cytomegalovirus (HCMV) is the immunodominant phosphoprotein 65 (pp65), which is freque

235 four dog groups were tested by WB to assess immunodominant protein recognition patterns: group I con

236 r T cells specific for cytomegalovirus-pp65 (immunodominant protein), tetanus toxoid, measles, mumps,

237 or vaccinia virus and Candida albicans-MP65 (immunodominant protein), typical pathogens of skin and/o

238 4/26 group III dogs were not reactive to any immunodominant protein.

239 seroreactive to one or more of six specific immunodominant proteins (13, 17, 29, 50, 56, and 150 kDa

240 Immunodominant proteins encoded by members of the variab

241 peptides used for B-cell epitope mapping of immunodominant proteins of Chlamydia spp.

242 Two immunodominant proteins of rotavirus, VP7 and VP4, deter

243 jective of this study was to characterize WB immunodominant proteins that could be used to confirm a

244 Some B. henselae SA2 immunodominant proteins were recognized by dogs experime

245 to 48 peptide antigens from 12 C. pneumoniae immunodominant proteins.

246 tigenically distinct lineages defined by the immunodominant receptor binding protein, haemagglutinin.

247 V2, with targeting of fewer epitopes in the immunodominant region of gp41 (gp41-ID) and the V1 regio

248 er peptide sequence covering the core of the immunodominant region of the allergen is a potential tar

249 ggesting that this antigenic domain forms an immunodominant region of the protein.

250 RC1 conceals non-conserved immunodominant regions by the addition of glycans and/or

251 Therefore, knowledge of these immunodominant regions is essential to proactively devel

252 ng linear B-cell peptides, we report two IgG immunodominant regions on SARS-CoV-2 spike glycoprotein

253 demonstrate that antibodies targeting these immunodominant regions significantly alter virus neutral

254 Overall, we identified a small number of immunodominant regions, which were in functionally impor

255 the C1, C2, V1, V2, and V3, C4, C5, and gp41 immunodominant regions.

256 CD4(+) and/or CD8(+) epitopes, including six immunodominant regions.

257 poor neutralizing antibody responses and an immunodominant response against gB antigenic domain 3 (A

258 of the viruses, and other mice developed an immunodominant response to a normally subdominant, cross

259 Vaccinated volunteers had an immunodominant response to the Gag293 epitope with a fun

260 In BALB/C mice the immunodominant response was shifted from the previously

261 n inhibitory receptor and in contrast to the immunodominant response, which is impaired.

262 e to an adult-like K(d)M282-90 CD8(+) T cell immunodominant response.

263 ce diversity and the propensity of eliciting immunodominant responses targeting variable regions of t

264 asmid DNA (pDNA) vaccine is able to redirect immunodominant responses to otherwise subdominant and of

265 ax is a commixture of a peptide representing immunodominant RSV CD8(+) T cell epitope M282-90, a TLR

266 cy related (DosR) latency, but not classical immunodominant secretory antigens, to clearly differenti

267 ution of humoral immune responses toward its immunodominant sequences in 90 patients with a range of

268 NA9D7 targets an immunodominant site, which may overlap the receptor-bind

269 nize several overlapping epitopes within the immunodominant site.

270 Rabbit immunization experiments identify key immunodominant sites of GP, while challenge studies in m

271 We identify two immunodominant SpCas9 T cell epitopes for HLA-A*02:01 us

272 antibody, gp120-binding antibody levels and immunodominant specificities, antibody-dependent cellula

273 Furthermore, this enriched immunodominant spike-specific antibody profile in conval

274 Immunodominant surface antigen B (IsaB) is a virulence f

275 genome backbones, in which loci that encode immunodominant surface proteins (ompA and pmpEFGH) have

276 to three of these peptide/HLA complexes-the immunodominant SVG9 (E protein), the subdominant SLF9 (N

277 d emphasize the capacity of HLA-C to present immunodominant T cell epitopes in HIV-infected individua

278 We sought to identify the immunodominant T cell epitopes of tropomyosin, the major

279 panning the whole alpha3IV-NC1 domain, three immunodominant T cell epitopes were identified.

280 The immunodominant T cell peptides identified were then fed

281 Remarkably, immunodominant T cell reactivities were directed against

282 Thus, an immunodominant T cell response can be due to a dominant

283 d, we here characterize the phenotype of the immunodominant T cell responses.

284 e many other major allergens, it contains an immunodominant T cell-activating region (Bet v 1142-156)

285 human B-cell surface receptors (CD19-22) to immunodominant T-cell antigens from EBV proteins, includ

286 5 or greater, affecting presentation of the immunodominant T-cell epitope in vitro.

287 v 1 homologs correlates with the presence of immunodominant T-cell epitopes.

288 virus and identified F, N, M2-1, M, and P as immunodominant target antigens.

289 ated the T cell responses that recognize the immunodominant Tax protein to the tax sequences present

290 lieving their lysis-dependent suppression by immunodominant TCD8 To our knowledge, our work constitut

291 ed CD8+ and/or CD4+ T cell responses against immunodominant TEM1 protein sequences.

292 for early priming of CD8 T cells against the immunodominant TMEV peptide VP2(121-130) Loss of H-2D(b)

293 tect infected host cells >20 hr earlier than immunodominant trans-sialidase-specific T cells.

294 ast cancer cell line that expresses the same immunodominant tumor Ag, AH1, but only necroptotic CT26

295 also limits T cell responses to potentially immunodominant tumor epitopes with limited expression in

296 17) show that T cells specific for different immunodominant vaccine antigens can fail to protect for

297 to steer human antibody responses away from immunodominant, variable epitopes and towards subdominan

298 luenza virus infection or vaccination target immunodominant, variable epitopes on the globular head r

299 o this conserved stem in the presence of the immunodominant, variable head domain of HA is challengin

300 anded from convalescent donors and recognize immunodominant viral epitopes in conserved regions of me

301 n asthmatic subjects, Bla-g 5, 9 and 11 were immunodominant, while, in contrast, nonasthmatic-sensiti