ライフサイエンスコーパス: immunogenic

1 a1 cluster encoding lipoproteins known to be immunogenic.

2 small fraction of predicted neoantigens are immunogenic.

3 -v was well tolerated, and, when adjuvanted, immunogenic.

4 en by DVI, and was safe, well tolerated, and immunogenic.

5 lotype does not necessarily imply it will be immunogenic.

6 g immunisation was well tolerated and highly immunogenic.

7 Proteins containing only CssA were weakly immunogenic.

8 facture and biologically unstable as well as immunogenic.

9 itopes are not predicted but are known to be immunogenic.

10 se regions at the top of the viral spike are immunogenic.

11 diture of energy to synthesize and is highly immunogenic.

12 east one infected mouse, and nearly 40% were immunogenic across more than half of the mice screened.

13 ivators of innate immune pathways and highly immunogenic adjuvants.

14 The optimized conjugates were immunogenic, alone and in combination, in mice and rhesu

15 cts of the tumor immune landscape, including immunogenic alterations, neoantigens, common cancer/test

16 taG-ZEBOV-GP vaccine appeared to be safe and immunogenic among the vaccinated individuals.

17 ented immunoassays for the compositional and immunogenic analyses of wheat beers.

18 ted humans, we further show that jhp_0775 is immunogenic and activates IFNgamma secretion from periph

19 rovides evidence for the existence of highly immunogenic and conserved epitopes across serotypes, whi

20 A single dose of TCV was immunogenic and effective in reducing S. Typhi bacteremi

21 d recombinant zoster vaccine (RZV) is highly immunogenic and efficacious in adults >=50 years (Y) of

22 The K. pneumoniae bioconjugates are immunogenic and efficacious, protecting mice against let

23 seen limited success in PDAC due to a poorly immunogenic and exceedingly immunosuppressive tumor micr

24 Cancer cells are poorly immunogenic and have a wide range of mutations, which ma

25 ctionated radiotherapy (LRT) can elicit both immunogenic and immunosuppressive local and systemic imm

26 Both novel OPV2 candidates were immunogenic and increased the median blood titre of seru

27 Necroptotic cell death is potently immunogenic and limits IAV spread by directly eliminatin

28 odified liposomes have been determined to be immunogenic and may have life-threatening consequences i

29 Adjuvanted FLU-v is immunogenic and merits phase 3 development to explore ef

30 he SARS-CoV-2 S-protein, in which the highly immunogenic and mobile receptor binding domain (RBD) is

31 However, these vaccines are weakly immunogenic and poorly protective.

32 he class 5 family (CFA/I) fimbria, is highly immunogenic and protects against oral challenge with CFA

33 ntigen instead of Gag was significantly less immunogenic and resulted in reduced protection.

34 The high number of peptides found to be immunogenic and the distribution of responses across mic

35 tion with DTaP-IPV-Hib, PCV13, and PPV23 was immunogenic and well tolerated.

36 e, the designed EEEV mutants remained highly immunogenic and, after a single dose, protected mice aga

37 on of genes of unrelated pathogens, is safe, immunogenic, and can incorporate large amounts of added

38 ncoding an attenuated rZIKV was safe, highly immunogenic, and provided full protection against lethal

39 chedule of PCV13 followed by PPSV23 is safe, immunogenic, and thus beneficial in the majority of IBD

40 ggregates by submitting infliximab (IFX), an immunogenic anti-TNF-alpha chimeric Ab, to heat stress.

41 oma (BL) that normally only express the less immunogenic antigen EBV nuclear antigen-1 (EBNA-1), rend

42 ex involving hemagglutinin (HA), the primary immunogenic antigen of the influenza virus, and the D1 H

43 dy-binding hot spots were identified in ZIKV immunogenic antigens, including membrane, envelope (E) a

44 sylation cannot be ignored in the search for immunogenic antigens.

45 d STING-NPs reprogram the TME towards a more immunogenic antitumor milieu, characterized by an influx

46 nducing drug is injected locally to generate immunogenic apoptotic fragments/cells.

47 receptor-binding domains (RBDs) in a highly immunogenic array and induce neutralizing antibody titer

48 odels PilA was consistently found to be more immunogenic as a subentity of the PE-PilA fusion protein

49 candidates were as safe, well tolerated, and immunogenic as monovalent OPV2 in previously OPV-vaccina

50 reactive, immunity and in particular, poorly immunogenic avian antigens.

51 Unbiased identification of individual immunogenic B-cell epitopes in major antigens of a patho

52 d pipeline, we have identified and validated immunogenic B-cell epitopes that are cross-reactive betw

53 immunoproteomics analysis, potentially novel immunogenic B. pertussis antigens were identified.RESULT

54 inal cancers are generally considered poorly immunogenic, basic research findings and data from clini

55 s to some extent, its limitations for highly immunogenic biotherapeutics have been demonstrated.

56 tumour immunity was activated in this poorly immunogenic breast cancer mouse model.

57 py as a novel management strategy for poorly immunogenic breast tumors.

58 lication sites acquire specificity to poorly immunogenic but conserved influenza hemagglutinin (HA) e

59 In this study, we show that highly immunogenic C. albicans hyphae attract phagocytic cells,

60 ally available KRAS(G12C) inhibitor to drive immunogenic cancer cell death, thus constituting a promi

61 Insulin B6-23, a highly immunogenic CD4 T-cell epitope in patients with T1D, bou

62 Immunogenic cell death (ICD) and tumour-infiltrating T l

63 Immunogenic cell death (ICD) converts dying cancer cells

64 helix secondary structure and induces robust immunogenic cell death (ICD) in cancer cells as characte

65 Mechanistically, MFP induced immunogenic cell death (ICD) in vivo and in vitro, as de

66 liposome formulation to deliver a potential immunogenic cell death (ICD) inducing agent, 17-(allylam

67 Immunogenic cell death (ICD) is a way of reengaging the

68 Immunogenic cell death (ICD) occurs when a dying cell re

69 cial or harmful, which is represented by the immunogenic cell death (ICD) paradigm or overexpression

70 ts, especially those produced as a result of immunogenic cell death (ICD), are known to be a potentia

71 a mode of drug-induced cell death, known as immunogenic cell death (ICD), can propagate antitumoral

72 Immunogenic cell death (ICD)-inducing modalities not onl

73 to hyperthermia and doxorubicin resulted in immunogenic cell death and the local release of type I i

74 nhibition of the MAPK and PI3K-AKT pathways, immunogenic cell death and the recruitment of infiltrati

75 diselenide bonds, resulting in DOX-mediated immunogenic cell death at the tumor site.

76 lded protein aggregates, ultimately inducing immunogenic cell death in dMMR cancer cells.

77 nstrating single-agent efficacy that induces immunogenic cell death in treated tumors.

78 (5FURW), paired with another common drug and immunogenic cell death inducing agent, doxorubicin (DOX)

79 conventional chemotherapeutics, SCNPs cause immunogenic cell death or ICD.

80 IRE induces immunogenic cell death, activates dendritic cells, and a

81 Viral infection can trigger immunogenic cell death, activating the immune system aga

82 ncluding lymphodepletion, T cell priming via immunogenic cell death, and inflammation; all occur with

83 xaliplatin/cyclophosphamide, shown to induce immunogenic cell death, and paclitaxel/carboplatin, repo

84 F3 and hence recruitment of MDSCs as well as immunogenic cell death, leading to an increase in inflam

85 e, the induction of ER stress often leads to immunogenic cell death, providing another factor that co

86 To leverage this immunogenic cell death, we combined MLN4924 treatment wi

87 heavily suppresses tumor growth and inducing immunogenic cell death, which is synergistic with Indoxi

88 ) treatment, indicated a strong induction of immunogenic cell death.

89 into tissue and elicit inflammation through immunogenic cell death.

90 es a foundation for future production of non-immunogenic, cellularized hiPSC-derived TEVGs composed o

91 Upon immunogenic challenge, lymph nodes become mechanically s

92 localized and this finding combined with the immunogenic characteristic of TF, has led us to determin

93 stributed into angiogenic and proliferative/ immunogenic clades.

94 Accordingly, we performed molecular and immunogenic comparisons of E2 produced in mammalian and

95 to both brain-derived and intestinal-derived immunogenic components.

96 dardizing the general design (e.g., species, immunogenic compound used, housing) of our MIA models bo

97 in caused by DMD gene mutations, without the immunogenic concerns associated with delivering dystroph

98 ly investigated to inform the development of immunogenic DCs for use as cellular therapies.

99 In response to infection, immunogenic DCs promote the generation of proinflammator

100 and a doxorubicin-iRGD conjugate enhance the immunogenic death of tumor cells, increase systemic tumo

101 , we have previously prepared a soluble, low immunogenic (DNA-free), tendon extracellular matrix frac

102 Non-motile bacteria are more immunogenic due to a lower expression of arnT upon host-

103 in in T. muris excretions/secretions, is non-immunogenic during infection and has an unusual sequence

104 identified decitabine as a potent inducer of immunogenic EBV antigens, including LMP1, EBNA2, and EBN

105 transforming programme, consisting of highly immunogenic EBV nuclear antigen (EBNA) and latent membra

106 We analyzed the immunogenic effect of 4 different medication regimens: (

107 Low-dose chemotherapy demonstrates several immunogenic effects that can favorably potentiate immuno

108 IRE and ECT show immunogenic effects that could be augmented when combine

109 their quaternary structure and impairs their immunogenic effects.

110 st vaccination protocol, these proteins were immunogenic, eliciting specific IgG antibodies.

111 These immunogenic elicitor peptides are embedded in the flagel

112 EBNA1 is poorly immunogenic, enabling tumors to evade immune responses.

113 hway, increase CD1d-mediated presentation of immunogenic endogenous lipid species, which results in e

114 nteraction between these cells and the local immunogenic environment is thought to be critical for lo

115 contribute to an immunosuppressive and less immunogenic environment, they exhibit an additional func

116 n, suggesting this region to be an important immunogenic epitope during human infection.

117 onsortium wherein each participant predicted immunogenic epitopes from shared tumor sequencing data.

118 tolerance to beta cells by inactivating key immunogenic epitopes of stem cell-derived beta cells int

119 We identified immunogenic epitopes of the tTG-DGP complex, and found t

120 We identified 172 immunogenic epitopes of the tTG-DGP complex.

121 In vivo, gluten immunogenic epitopes were decreased by 60% in the stomac

122 Peptide microarrays may help to identify immunogenic epitopes, define correlates of vaccine prote

123 Two immunogenic epitopes, ESAT6(1-20) and TB10.4(3-11) from

124 cans to open new holes that might expose new immunogenic epitopes.

125 lycosylation plays a known role in shielding immunogenic epitopes.

126 netic therapy with decitabine can upregulate immunogenic Epstein-Barr virus (EBV) antigens on Burkitt

127 films in vitro These experiments support the immunogenic equivalence between fused PE-PilA and isolat

128 cells enhanced the expression of Plasmodium immunogenic factors and exacerbated subsequent systemic

129 eutrophils from cell death induced by highly immunogenic foreign antigens.

130 (MS) and mis-splicing of exons create highly immunogenic frameshift (FS) neoantigens in tumors.

131 eta as a key regulator for DC maturation and immunogenic functionality under homeostatic and lymphoma

132 plication detected in 90% of vaccinees), and immunogenic (geometric mean serum RSV plaque-reduction n

133 e anti-glioma agent when encapsulated in non-immunogenic glioma-targeted liposomes, which may contrib

134 This analysis suggests immunogenic gluten may peak within the intestinal duoden

135 ated synthetic peptide comprising repetitive immunogenic gluten motifs.

136 e the profile and kinetic release pattern of immunogenic gluten peptides in a physiologically relevan

137 gestibility and the deamidation state of six immunogenic gluten peptides within bread was investigate

138 te to retain its natural orientation and its immunogenic groups.

139 Antigens that present this broadly immunogenic HA epitope may be good candidates for inclus

140 nidase inhibitor, zanamivir, with the highly immunogenic hapten, dinitrophenyl (DNP), which specifica

141 on of viral pMHCI on infected cells that are immunogenic has not been shown for any virus.

142 We modified a safe form of VSV to express an immunogenic HBV protein and evaluated the efficacy of th

143 une-priming approaches that sensitize poorly immunogenic HNSCCs to checkpoint blockade.

144 a "cold" tumor microenvironment to become an immunogenic, "hot" tumor microenvironment, working in sy

145 V] one fifth of normal IPV dose) is safe and immunogenic; however, id administration is perceived as

146 n with 3 doses of PCV10 or PCV13 is safe and immunogenic in a highly endemic setting; however, to sig

147 PAMVAC was immunogenic in all participants.

148 prisingly high fraction (>80%) of pMHCI were immunogenic in at least one infected mouse, and nearly 4

149 V2 candidates were safe, well tolerated, and immunogenic in children and infants.

150 e World Health Organization (WHO) and highly immunogenic in children under 5, has the potential to re

151 This glycopeptide is strongly immunogenic in eliciting glycan-dependent cellular and h

152 A 2-dose schedule is highly immunogenic in girls, suggesting a high immune memory.

153 vaccine that has been demonstrated safe and immunogenic in HCMV-seronegative subjects.

154 ficile vaccine was safe, well tolerated, and immunogenic in healthy US adults aged 65-85 years.

155 nt CBFB-MYH11 fusion protein was found to be immunogenic in HLA-B*40:01+ donors.

156 tope of influenza hemagglutinin (HA) that is immunogenic in humans and conserved among influenza subt

157 Furthermore, we show that 6PGD(391-410) is immunogenic in humans, as healthy human and AAV patient

158 that the novel OPV2 candidates were safe and immunogenic in IPV-immunised adults, and our data suppor

159 GMZ2 is well tolerated and immunogenic in lifelong-Pf-exposed adults from Gabon, wi

160 Oral poliovirus vaccine (OPV) is less immunogenic in low- or middle-income than in high-income

161 t membrane glycoprotein polymorphisms can be immunogenic in man and are frequently the cause of clini

162 encodes the spike protein of SARS-CoV-2, is immunogenic in mice and elicites a robust humoral and ce

163 d chimera, dsc(14)CfaE-sCTA2/LTB, was highly immunogenic in mice when administered intranasally or in

164 d V. parahaemolyticus was produced and found immunogenic in mice.

165 onstrated that spleen-dependent antigens are immunogenic in natural infections and that antibodies to

166 etically stable, replication restricted, and immunogenic in nonhuman primates.

167 leocapsid protein that is known to be highly immunogenic in other coronaviruses.

168 r virus (VZV) vaccine appears to be safe and immunogenic in pediatric solid organ transplant recipien

169 Prior work established that nOPV2 is immunogenic in preclinical and clinical studies, and thu

170 ESAT-6 was only immunogenic in QFT-negative participants who received th

171 candidate RSV vaccine that is attenuated yet immunogenic in RSV-seronegative children, warranting fur

172 unlike parental tumors, YOVAL1.1 tumors are immunogenic in vivo and can be controlled by immunothera

173 hesized that inducing expression of the more immunogenic latent viral antigens expressed in EBV type

174 omotes GB cell death and the release of high immunogenic levels of granulocyte-macrophage colony stim

175 findings demonstrating that the C. difficile immunogenic lipoprotein CD0873 plays a critical role in

176 n genetically stable, highly attenuated, and immunogenic live virus vaccine candidates for RSV.IMPORT

177 s have shown M2e-based vaccines are strongly immunogenic, making it an attractive target for further

178 rorobots, and will serve as a toolbox of non-immunogenic materials for medical microrobot and other d

179 ing radiation drives increased production of immunogenic micronuclei, leading to systemic tumor respo

180 50% of peptides identified contained celiac-immunogenic motifs, and consumption of wheat beers would

181 Using the poorly immunogenic mouse B16F10 melanoma model, we initiated tr

182 ons (fs-indels) are an infrequent but highly immunogenic mutation subtype.

183 trating lymphocytes to identify the specific immunogenic mutations expressed in patients' tumors.

184 models and divided them into two classes of immunogenic mutations.

185 ation of oAd is severely restricted by their immunogenic nature and poor tumor homing ability, thus o

186 tment modalities for patients with TNBC, the immunogenic nature of this aggressive disease has presen

187 Immunogenic neo-epitopes were recognized by autologous T

188 The identification of immunogenic neoantigens and their cognate T cells repres

189 elines to sensitively and accurately predict immunogenic neoantigens from next-generation sequencing

190 emonstrate that gene fusions are a source of immunogenic neoantigens that can mediate responses to im

191 inflammation and the display of potentially immunogenic neoantigens.

192 of unknown function, bbk13, which encodes an immunogenic, non-surface-exposed membrane protein that i

193 not bind to B7.2 and, hence, it was neither immunogenic nor antigenic.

194 stalk domain of the NA could render it more immunogenic on virus particles.

195 into the epigenetic mechanisms that restrict immunogenic oncoprotein expression, a genome-scale CRISP

196 gene delivery vector must be non-toxic, non-immunogenic, overcome extra- and intra-cellular barriers

197 The identification of immunogenic pathogen-derived epitopes and a detailed und

198 acute ability of plants to detect conserved immunogenic patterns from their enemies, even from seemi

199 fic non-canonical HLA peptides, including an immunogenic peptide derived from an open reading frame d

200 Novel ways to present protective immunogenic peptide epitopes to human immune systems are

201 t presentation of a particular BKPyV-derived immunogenic peptide.

202 vel Kgp synthetic peptides tested herein are immunogenic peptides (epitopes) since they induced the p

203 mine the clinical usefulness of urine gluten immunogenic peptides (GIP) as a biomarker monitoring GFD

204 Our previous in silico study predicted 16 immunogenic peptides from Kgp protein.

205 he deamidation state or digestibility of the immunogenic peptides investigated.

206 receptors (TCRs) of T-cells and potentially immunogenic peptides presented by MHCs of antigen presen

207 can result in the formation of neoantigens, immunogenic peptides that are presented on the tumor cel

208 The effect of mTG on six immunogenic peptides was investigated by in vitro digest

209 immunogenicity that filtered out 98% of non-immunogenic peptides with a precision above 0.70.

210 truction, in the form of T-cell recognizable immunogenic peptides, also known as neoantigens.

211 Untargeted proteomics identified 83 immunogenic peptides.

212 thms may increase the prediction accuracy of immunogenic peptides.

213 itate tumor antigen presentation by enabling immunogenic photodynamic therapy (PDT) and promoting the

214 he secreted protein MPT64, which is a highly immunogenic polypeptide of Mycobacterium tuberculosis, a

215 on to humans, a fusion protein consisting of immunogenic portions of PdSP15 and LJL143, sand fly sali

216 ies and enable computational analysis of the immunogenic potential of a given protein sequence region

217 In this study, the composition and immunogenic potential of seven commercially available wh

218 The immunogenic potential of the PE and PilA within the fusi

219 To gain insights into the immunogenic potential of these tumors, we conducted whol

220 n CD11c(+) dendritic cells (DCs) with higher immunogenic potential, lower frequency of Foxp3(+) regul

221 tions) for increased stability in the highly immunogenic prefusion (pre-F) conformation, with or with

222 Bacterial (bact)DNA is an immunogenic product that frequently translocates into th

223 dose regimen of VSV-EBOV revealed a safe and immunogenic profile and demonstrated clinical efficacy.

224 Delta123r and Delta123A7r recapitulated the immunogenic properties of cell culture-derived D123-HMW

225 zation contributes to further unraveling the immunogenic properties of fHbp.

226 In this regard, despite the poor immunogenic properties of NB, the success of antibody-ba

227 d even heat-treated without compromising the immunogenic properties of TTCF.

228 ies reflect the dissimilar physiological and immunogenic properties of WTA and LTA.

229 chanical properties, anti-biofouling and non-immunogenic properties, functionalization for magnetic a

230 ing the course of transformation despite its immunogenic properties.

231 ctivation in various cancer types, and their immunogenic properties.

232 Collectively, our results reveal the immunogenic property of Asp t 36, a major allergen from

233 confirmed by the rBipA (recombinant Borrelia immunogenic protein A) Western blot.

234 rotect, modify, deprotect (PMD), to generate immunogenic proteins aimed to direct a vaccine-induced a

235 in differ by two amino acids in the critical immunogenic region (aa 9-23) of the B chain.

236 without hypervariable region 1, which is an immunogenic region associated with viral escape.

237 its conformation, as well as redesigns of an immunogenic region to add a new N-glycosylation site and

238 In addition, the main-immunogenic-region-like domain of alpha7 went through co

239 pitopes across the four serotypes within the immunogenic regions of NS3, NS4B and NS5.

240 However, immunogenic response and long-term toxicity with the use

241 ming that specifically favors glycolysis and immunogenic response by DCs.

242 A was safe and induced a particularly robust immunogenic response in combination with GLA-SE.

243 al ACL but is decellularized for a decreased immunogenic response.

244 orylation (OXPHOS) to glycolysis to mount an immunogenic response.

245 tides was an effective strategy to elicit an immunogenic response.

246 could contribute to angiogenesis and altered immunogenic responses in ovarian cancer.

247 cells (LC) can prime tolerogenic as well as immunogenic responses in skin, but the genomic states an

248 ell death protein 1 (PD-1) ligation delimits immunogenic responses in T cells.

249 while attenuating excessive inflammatory and immunogenic responses in the epidermis.

250 abolism, which regulates the tolerogenic and immunogenic responses of DCs.

251 ogeneic cell lines in vitro, in line with an immunogenic role of allogeneic DERAA.

252 cines, we established that the use of highly immunogenic rPfMSP8 as a carrier protein for leading vac

253 he surface-exclusion protein (SpyAD) and the immunogenic secreted protein 2 (Isp2) were found to be c

254 ability can result in reduced potency, cause immunogenic side effects, and limit options for formulat

255 surface and creates a mapping of potentially immunogenic sites on Env.

256 Here, non-immunogenic stealth zwitterionic microrobots that avoid

257 of expansion and the requirement for ongoing immunogenic stimulation.

258 show that uUtro is a highly functional, non-immunogenic substitute for dystrophin, preventing the mo

259 most cancers and offer a specific and highly immunogenic target for personalized vaccination.METHODSW

260 ed in viral-host cell fusion, is the primary immunogenic target for virus neutralization and the curr

261 going SARS-CoV-2 pandemic, identification of immunogenic targets against the coronavirus spike glycop

262 t upon knockout of AH1, necroptosis was more immunogenic than apoptosis in a prophylactic tumor vacci

263 BCG-Denmark and BCG-Japan were more immunogenic than BCG-Russia by the measures traditionall

264 a may be feasible but likely need to be more immunogenic than natural infection.

265 d trivalent influenza vaccine (aTIV) is more immunogenic than similarly-dosed non-adjuvanted trivalen

266 charide analogue of Lewis Y antigen was more immunogenic than that of the hexasaccharide analogue, bu

267 lts suggest that the ACE2IS has evolved less immunogenic than the other regions of the spike protein,

268 Last, a virus lacking A49 was more immunogenic than the WT virus.

269 Unmodified circRNA is less immunogenic than unmodified linear mRNA in vitro, in par

270 t vaccine-encoded adapted epitopes were less immunogenic than vaccine-encoded nonadapted epitopes, an

271 es frequently mutated in human cancer can be immunogenic, thus offering a rapid way to screen for can

272 ls that PBRM1 loss is associated with a less immunogenic TME and upregulated angiogenesis.

273 ly improve antitumor efficacy against poorly immunogenic TNBCs.

274 nclusion, the BMDC adoptive transfer-induced immunogenic tolerance in OVA-sensitized mice might not b

275 S3(-/-) DCs slightly attenuated BMDC-induced immunogenic tolerance.

276 lead to potent tumor inhibition in a poorly immunogenic triple negative breast cancer model.

277 ignifying novel groups of potentially highly immunogenic tumor antigens.

278 Antiprogestin therapy induces immunogenic tumor cell death in PRA-overexpressing tumor

279 A non-immunogenic tumor microenvironment (TME) is a significan

280 ibits pathologic heterogeneity and a dynamic immunogenic tumor microenvironment (TME).

281 ancy typified by a highly stromal and weakly immunogenic tumor microenvironment that promotes tumor e

282 In a low-immunogenic tumor model, DNA demethylation upregulates c

283 Abs enhanced tumor suppression in the mouse immunogenic tumor model.

284 In the immunogenic tumor models, we observed significant tumor

285 of a proportion of late stage patients with immunogenic tumor types.

286 of checkpoint blockade-resistant and poorly immunogenic tumors in mice after injecting adjuvant-free

287 Poorly immunogenic tumors, including triple negative breast can

288 RCC is considered to be an immunogenic tumour but is known to mediate immune dysfun

289 By far the most immunogenic vaccine candidates for antibody responses ar

290 The most immunogenic vaccine regimen in nonhuman primates among t

291 in increased CD8(+) T-cell memory and a more immunogenic vaccine.IMPORTANCE NF-kappaB is a critical t

292 More immunogenic vaccines are needed for pregnant women livin

293 Although immunogenic, VZV vaccination did not result in significa

294 Moreover, the chimera was safe and highly immunogenic when administered intradermally to guinea pi

295 as replaced by dsc(19)CfaE that was strongly immunogenic when administered intranasally or orogastric

296 29 ug g(-1) fresh leaf tissue and was deemed immunogenic when administered to BALB/c mice either oral

297 dose administered 4-6 years post-dose 1 was immunogenic with a favorable safety profile.

298 e dose administered 4-6 years postdose 1 was immunogenic with a favorable safety profile.

299 All vaccines were highly immunogenic with similar kinetics and comparable peak gB

300 All regimens were well tolerated and immunogenic, with trends toward higher anti-circumsporoz