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1 DEIA groups, except for level of total serum immunoglobulin E.
2 mpaired in mastocytosis or allergen-specific immunoglobulin E.
3 r "aptamer" designed to bind specifically to immunoglobulin E.
4 d by T helper type 2 cytokines and increased immunoglobulin E.
5 high levels of interleukin (IL)-5, IL-4, and immunoglobulin E.
6 n 5 in the lung, and reduced serum levels of immunoglobulin E.
7 s to common allergens, which are mediated by immunoglobulin E.
8 rface expression by a 4-d preincubation with immunoglobulin E.
9 lergic inflammation, as measured by elevated immunoglobulin E.
10 rmalized circulating levels of cytokines and immunoglobulin E.
11 lycerides,.37; diastolic blood pressure,.21; immunoglobulin E,.63; lipoprotein(a),.77; and body-mass
12 of airway medication, blood eosinophils, and immunoglobulin E (adjusted OR [aOR], 3.56 [95% CI, 2.51-
15 aggregation of Fc epsilon RI receptors with immunoglobulin E and antigen is mediated through the act
17 asthma phenotypes, such as high total serum immunoglobulin E and bronchial hyperresponsiveness, have
22 -alpha-treated mice exhibited elevated serum immunoglobulin E and inhibition of the anticryptococcal
24 oded nanopores to detect single molecules of immunoglobulin E and the bioterrorist agent ricin, seque
25 h2 response was accompanied by production of immunoglobulin E and the sensitization of circulating ba
26 eutic approaches, including the targeting of immunoglobulin E and tumour necrosis factor alpha with b
27 a mutant deficient in delta-toxin, promoted immunoglobulin-E and interleukin-4 production, as well a
28 amers against a surface-immobilized protein (immunoglobulin E) and a solution-phase small molecule (b
30 Th2 cell skewing was dependent on basophils, immunoglobulin E, and interleukin-4, but was independent
35 at year 1 and repeated assessments of serum immunoglobulin E antibodies (year 1, 4.5, 6), atopic der
36 xpectedly, FcgammaRIV 'preferentially' bound immunoglobulin E antibodies of the 'b' allotype (IgE(b))
37 allergens in home dust samples, and specific immunoglobulin E antibodies were measured at outset, and
38 ex sensitization (measured by latex-specific immunoglobulin E antibodies) by using data from 5,512 ad
40 rotocol including measurement of HE-specific immunoglobulin E-antibodies in serum, skin prick tests,
42 test positivity (SPT), and allergen-specific immunoglobulin E (asIgE) after 3 years of intervention.
43 e poor correlation between allergen-specific immunoglobulin E (asIgE) and clinical signs of allergy i
44 fector cells in allergic disorders and other immunoglobulin E-associated acquired immune responses th
45 on as effector and immunoregulatory cells in immunoglobulin E-associated allergic disorders, as well
46 -6, CXCL8), IL-12, CCL11, thromboxane B2 and immunoglobulin E at 24 h after local allergen challenge.
47 RI subunits for the formation of functional, immunoglobulin E-binding FcepsilonRI complexes during en
48 n-specific T-cell responses by internalizing immunoglobulin E-bound antigens for presentation to anti
50 erin ectodomains fused to the Fc fragment of immunoglobulin (E-cad/Fc, N-cad/Fc, and P-cad/Fc) and im
51 llergen specificity, allergen-specific serum immunoglobulin E concentration, or individual laboratory
53 +)) influx; however, unlike that mediated by immunoglobulin-E crosslinking, it did not require the sp
54 49B1 is expressed on mast cells and inhibits immunoglobulin E-dependent activation and inflammation i
55 ved in the recruitment of neutrophils during immunoglobulin E-dependent gastric inflammation in the m
57 s can exacerbate ADHD symptoms and cause non-immunoglobulin E-dependent histamine release from circul
59 ond important action of ISS is inhibition of immunoglobulin E-dependent release of Th2 cytokines, esp
62 andard was carried out for allergen-specific immunoglobulin E determination using the fluoroimmunoenz
64 kin tests and measurement of serum levels of immunoglobulin E do not accurately identify foods for el
66 otal immunoglobulin E (TIgE), serum-specific immunoglobulin E, eosinophil count in peripheral blood,
68 Aggregation of high-affinity receptors for immunoglobulin E (Fc epsilon RI) on the surface of mast
69 aling through the high affinity receptor for immunoglobulin E (Fc epsilon RI) results in the coordina
70 ss-linking of the high-affinity receptor for immunoglobulin E (FcepsilonRI) results in release of inf
73 n mediated by the high-affinity receptor for immunoglobulin E, FcepsilonRI, but the molecular basis i
76 associated with increased allergen-specific immunoglobulin E (IgE) against a range of environmental
78 etecting human immunoglobulin G (IgG), human immunoglobulin E (IgE) and Aspergillus fumigatus antibod
79 ory-like', increased serum concentrations of immunoglobulin E (IgE) and caused dendritic cells to pro
80 d candidate genes for association with total immunoglobulin E (IgE) and effect modification by 25-hyd
82 cells express the high-affinity receptor for immunoglobulin E (IgE) and have been linked to host defe
84 About 20 years after the identification of immunoglobulin E (IgE) and its key role in allergic hype
85 , this treatment increases parasite-specific immunoglobulin E (IgE) and other Th2 responses in the mo
86 s, characterized by increases in total serum immunoglobulin E (IgE) and specific serum IgG1 levels an
91 isdirected type 2 immune responses, in which immunoglobulin E (IgE) antibodies are produced against a
96 nsor, featuring a highly specific anti-human immunoglobulin E (IgE) aptamer as a capture probe, for h
98 he first to report high levels of functional immunoglobulin E (IgE) autoantibodies recognizing brain
100 ne if D-amino acids (D-aas) bind and inhibit immunoglobulin E (IgE) binding to peanut allergens.
101 ), stably cross-links anti-2,4-dinitrophenyl-immunoglobulin E (IgE) bound to high affinity receptors
102 n: FM by plethysmography, total and specific immunoglobulin E (IgE) by automated immunosorbent analys
103 everal extracellular cues, including antigen-immunoglobulin E (IgE) complexes, bacteria, viruses, cyt
105 Framingham Heart Study data on total plasma immunoglobulin E (IgE) concentrations and found a number
106 nts stimulated by the mast cell receptor for immunoglobulin E (IgE) correlated with the affinity of a
110 gths (I) on allergen extractability from and immunoglobulin E (IgE) immunoreactivity of peanut, almon
111 ctivated B lymphocyte increases the level of immunoglobulin E (IgE) in a protein kinase A (PKA)- and
113 n of low concentrations of allergen-specific Immunoglobulin E (IgE) in human sera using a Photonic Cr
114 itative immunoassay for the determination of immunoglobulin E (IgE) in human serum using gold nanoclu
116 high-affinity Fc receptor (FcepsilonRI) for immunoglobulin E (IgE) in MC/9 mouse mast cells stimulat
118 lper (Th) 2 cells, the physiological role of immunoglobulin E (IgE) in the airway remains largely und
123 r-based biosensor for the detection of human immunoglobulin E (IgE) is developed using the electroche
132 study examined the association between serum immunoglobulin E (IgE) levels for a panel of common indo
133 rhinitis, and itchy rash) and serum-specific immunoglobulin E (IgE) levels from the 2005-2006 Nationa
137 ry, maternal and paternal total and specific Immunoglobulin E (IgE) levels, and cord blood IgE were r
138 erresponsiveness (BHR), elevated total serum immunoglobulin E (IgE) levels, and skin tests positive t
139 ed based on increased IL-5 production, total immunoglobulin E (IgE) levels, antigen-specific IgG1 res
140 f intermediate phenotypes, one each on serum immunoglobulin E (IgE) levels, blood eosinophil counts a
145 estigated how the high-affinity receptor for immunoglobulin E (IgE) modulates the response of mast ce
147 acebo-controlled clinical trials of the anti-immunoglobulin E (IgE) monoclonal antibody, rhuMAb-E25 (
148 e current study, we used omalizumab, an anti-immunoglobulin E (IgE) monoclonal antibody, to demonstra
149 ividuals is that parasite-induced polyclonal immunoglobulin E (IgE) out-competes allergen-specific Ig
150 omosome 14q was screened for loci modulating immunoglobulin E (IgE) phenotypes in 15 extended and 45
151 ing the serum of the patient showed specific immunoglobulin E (IgE) positivity for wasps; therefore,
153 as suggested an increase in antigen-specific immunoglobulin E (IgE) production during viral infection
154 draining lymph node (DLN) cell infiltrates, immunoglobulin E (IgE) production, and airway hyper-resp
155 igated the relationship between the specific immunoglobulin E (IgE) profile for 40 allergens using a
159 abilities, we analyzed a published model for immunoglobulin E (IgE) receptor signaling using syntheti
161 and basophils that express the high-affinity immunoglobulin E (IgE) receptor, Fc epsilon receptor 1 (
166 by which allergic patients develop specific immunoglobulin E (IgE) responses to environmental allerg
168 he basis of immune deviation that results in immunoglobulin E (IgE) sensitization and allergic reacti
170 ociated with concomitant atopic diseases and immunoglobulin E (IgE) sensitization to food allergens i
171 gher baseline levels of schistosome-specific immunoglobulin E (IgE) than did children with > or =2 re
173 s is reported for the sensitive detection of immunoglobulin E (IgE) using fluorescence polarization (
174 isease and asthma, and more than 30 yr since immunoglobulin E (IgE) was identified as the key molecul
175 nce and binding properties of an aptamer for immunoglobulin E (IgE) was investigated using custom DNA
176 ns at the site of infection and infection of immunoglobulin E (IgE)(-/-) mice, lead us to suggest tha
178 CD4-CD8- peripheral T cells, elevated serum immunoglobulin E (IgE), and possible pulmonary inflammat
179 markers of Th2 inflammation, reducing serum immunoglobulin E (IgE), chemokine ligands 13 and 17 by a
180 r, the level of a systemic Th2 marker, serum immunoglobulin E (IgE), correlated significantly with SR
181 cells by phosphorylation of the receptor for immunoglobulin E (IgE), FcepsilonRI, by Lyn kinase after
182 g by antigen, the high affinity receptor for immunoglobulin E (IgE), FcepsilonRI, is phosphorylated b
183 y fever, allergic sensitization, serum total immunoglobulin E (IgE), forced expiratory volume in one-
184 of allergens, and geometric mean serum total immunoglobulin E (IgE), in 3451 participants aged 18-75
187 The distinguishing structural feature of immunoglobulin E (IgE), the antibody responsible for all
188 We identified unique signatures for AD (Immunoglobulin E (IgE), thymus- and activation-regulated
190 orm of treatment for patients suffering from immunoglobulin E (IgE)-associated allergy; the most comm
191 parvalbumin, which was shown to have reduced immunoglobulin E (IgE)-binding capacity upon calcium dep
192 ophil IL-4 production after stimulation with immunoglobulin E (IgE)-containing immune complexes.
193 f LPA were functional, as evidenced by their immunoglobulin E (IgE)-dependent histamine release and b
195 an emphasis on novel FcepsilonRI regulators, immunoglobulin E (IgE)-independent pathways [e.g., Mas-r
198 of intracellular calcium concentration upon immunoglobulin E (IgE)-mediated crosslinking of the high
204 a consequence of antigen-aggregation of the immunoglobulin E (IgE)-occupied high affinity receptor f
214 nsitivity (DTH) to SEA; high levels of serum immunoglobulin E (IgE); a strong T2 cytokine phenotype w
218 tood, the disease is mediated by an abnormal immunoglobulin-E immune response in the setting of skin
220 complete lack of prevailing Sm-p80-specific immunoglobulin E in a high-risk or infected population w
222 gen-specific serum immunoglobulins and total immunoglobulin E in different groups of animals were mea
224 sis in the jejunum and had reduced ovalbumin-immunoglobulin E in their serum, compared with TSLPR(+/+
225 These studies highlight a mast cell- and immunoglobulin E-independent role for CCR6-bearing T cel
226 essential role in antigen sensitization and immunoglobulin E induction, stimulate dendritic cell acc
227 Also, substantial reductions in plasma total immunoglobulin E, interleukin (IL)-1beta, and tumor necr
230 rd the T helper 2 type, with increased total immunoglobulin E levels (P<.06) and a tendency toward in
231 OVA-specific Th1 to Th2 cells and decreased immunoglobulin E levels after allergen challenge as adul
232 antigen treatments resulted in reduced total immunoglobulin E levels and peripheral blood eosinophil
233 g doxorubicin and trastuzumab, high baseline immunoglobulin E levels are associated with a lower risk
234 tions between multiple VDR polymorphisms and immunoglobulin E levels were also observed (p = 0.006-0.
235 l alkaline phosphatase (PLAP) and polyclonal immunoglobulin E levels were also quantified in paired m
236 h doxorubicin and trastuzumab, high baseline immunoglobulin E levels were associated with a significa
238 4 production by NKT cells, to increase serum immunoglobulin E levels, and to promote the generation o
239 urrent viral and bacterial infections, hyper-immunoglobulin E levels, eczema, and greater susceptibil
240 allenge with ovalbumin, as measured by total immunoglobulin E levels, ovalbumin-specific immunoglobul
241 iotemporal dynamics of the redistribution of immunoglobulin E-loaded receptors (IgE-FcepsilonRI) on r
242 etion of cytokines involved in regulation of immunoglobulin E, mast cells, basophils and eosinophils,
243 lower immunoglobulin A (median, 1:3,200) and immunoglobulin E (median, 1:128) titers to rAls3p-N by e
248 tive incidence to be 0.34% by 1 year of age; immunoglobulin E-mediated cow's milk allergy was 0.5%.
251 rvoir after antigen capture through specific immunoglobulin E molecules bound to their FcepsilonRI.
253 FcepsilonRI, the high-affinity receptor for immunoglobulin E, on RBL-2H3 mast cells results in its c
256 y enhanced type 2 responses (IL-4, IL-5, and immunoglobulin E production) upon in vitro TCR stimulati
257 mal allergen-induced airway hyperreactivity, immunoglobulin E production, mucus metaplasia, and airwa
260 inst the protein extracts revealed different Immunoglobulin E reactivity of sera according to the ins
261 sera from soybean-sensitive individuals have immunoglobulin E reactivity to abundant storage proteins
263 these cells, cross-linking the high-affinity immunoglobulin E receptor (FcepsilonR1) leads to activat
266 f macrophages that express the high-affinity immunoglobulin E receptor FcepsilonRIalpha and are in cl
269 lso showed functional defects; high-affinity immunoglobulin E receptor-mediated degranulation was sig
270 tive [Lin-]/CD34hi/CD117int/hi/high-affinity immunoglobulin E receptor-positive [FcepsilonRI+]), with
272 (IL)-4 and IL-5 and posttreatment levels of immunoglobulin E recognizing the parasite's tegument (Te
273 Robert L. Coffman recounts how his work on immunoglobulin E regulation along with data from Tim Mos
274 duce iBALTs, which coincided with subsequent immunoglobulin E responses, and IL-1-receptor-deficient
276 d treatments of asthma, rhinitis and eczema; immunoglobulin E sensitization; weight; and height.
277 disease, which is frequently associated with immunoglobulin-E sensitization to ubiquitous fungi, typi
278 rgies were excluded by negative results from immunoglobulin E serology analysis and skin tests for co
279 ences in the number of sensitizations, total immunoglobulin E serum levels and predilection of the sk
280 termined by skin prick tests (SPT); specific immunoglobulin E (sIgE) titers against 12 common allerge
281 story rates and peanut- and Ara h 2-specific immunoglobulin E (sIgE) titers were significantly higher
282 to analyze the diagnostic value of specific immunoglobulin E (sIgE) to Gly m 2S albumin, Gly m 4, 5,
283 e, history, skin prick test, peanut specific immunoglobulin E (sIgE), and total IgE minus peanut sIgE
285 efit from targeted anti-interleukin and anti-immunoglobulin E therapies, and in monitoring subsequent
288 hacholine (MTCH)-challenge test, serum total immunoglobulin E (TIgE), serum-specific immunoglobulin E
289 immunoglobulin E levels, ovalbumin-specific immunoglobulin E titers, and eosinophil content of bronc
293 re added, with oral corticosteroids and anti-immunoglobulin E treatment with omalizumab for the most
295 in serum antigen-specific immunoglobulin G1/immunoglobulin E using ovalbumin or Aspergillus fumigatu
296 d gel-phase membranes displaying ligands for immunoglobulin E, using total internal reflection fluore
298 kers of oxidative stress, thromboxane B2 and immunoglobulin E were measured in bronchoalveolar lavage
299 alloproteinase-9 total, apolipoprotein E and immunoglobulin E--were used along with co-variates in mu
300 t differences between cases and controls was immunoglobulin E, with higher levels detected at baselin