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1 min, immunoglobulin A, immunoglobulin G, and immunoglobulin M).
2 as used to screen serum samples for anti-CMV immunoglobulin M.
3 red among 54%, but only 3% were positive for immunoglobulin M.
4 IL-7R and EBF but not B220, and can produce immunoglobulin M.
5 ng antibody and T-cell-independent antiviral immunoglobulin M.
6 uction of early T-cell-independent antiviral immunoglobulin M.
7 of the CSF samples tested positive for ZIKV immunoglobulin M.
11 azards model using bone marrow infiltration, immunoglobulin M, albumin, and beta-2 microglobulin valu
12 globulins enriched with immunoglobulin A and immunoglobulin M alleviated the symptoms of sickness beh
13 ox/lox)-CD19(+/Cre) mice have an increase in immunoglobulin M and CD43 and a decrease in CD5 expressi
15 ent assay for anti-HCMV immunoglobulin G and immunoglobulin M and for cIL-10 and vIL-10 levels using
17 n in 67% and complement fixation in 70%, and immunoglobulin M and G antibodies were demonstrated by e
18 pairing that significantly increases primary immunoglobulin M and IgG responses to TI-2 Ags as well a
19 immune markers of mortality, while anti-LVS immunoglobulin M and IL-1beta were associated with survi
20 r periorbital edema and Trichinella-specific immunoglobulin M and immunoglobulin G antibodies after e
21 coronavirus 2 was positive in 33.6%, whereas immunoglobulin M and immunoglobulin G antibodies were po
22 tion, and intrathecal synthesis of borrelial immunoglobulin M and immunoglobulin G antibody in 100%,
24 ces of galactose expression or deposition of immunoglobulin M and immunoglobulin G were found in xeno
25 LD), an enzyme immunoassay (EIA) followed by immunoglobulin M and immunoglobulin G Western blots, per
26 it is characterized by low levels of surface immunoglobulin M and impairment of calcium mobilization
27 (-) T cells, and decreases in elevated serum immunoglobulin M and inflammatory markers including inte
28 gulated the expression of cell surface CD22, immunoglobulin M and major histocompatibility complex cl
29 eroprevalence of ZIKV was 6.2% based on ZIKV immunoglobulin M and negative for dengue reactivity.
32 6 or more days after symptom onset (and the immunoglobulins M and G in all 33 samples collected at l
33 d human serum protein, immunoglobulin G, and immunoglobulin M), and demonstrated a high correlation w
34 iters of serum and cerebrospinal fluid (CSF) immunoglobulin M, and occasionally positive results of W
35 circulating transitional B cells, increased immunoglobulin M, and reduced immunoglobulin G2 levels i
37 on, we found that Ad is opsonized by natural immunoglobulin M antibodies and complement and that thes
38 sult); and 17 had only positive findings for immunoglobulin M antibodies and did not meet the definit
39 o-treat autoimmune hemolytic anemia in which immunoglobulin M antibodies bind to erythrocytes and fix
45 in G antibodies, and sometimes low levels of immunoglobulin M antibodies, to Borrelia burgdorferi (Bb
47 donors identified with early WNV infection (immunoglobulin M antibody negative) and those with uncon
49 ble case required fever and a positive rapid immunoglobulin M antibody test for typhoid (TUBEX TF); a
51 in the United States, confirmed by high ZIKV immunoglobulin M antibody titers in serum and cerebrospi
52 he infection when low levels of neutralizing immunoglobulin M antibody were detected in wild-type mic
53 fected CD28(-/-) mice produced primarily the immunoglobulin M antibody, which upon passive transfer p
54 termined that the measurement of Mp-specific immunoglobulin M antibody-secreting cells (ASCs) by enzy
55 ipid rafts in response to ligation with anti-immunoglobulin M (as a surrogate for antigen) are featur
58 IL-21 integrated signals mediated by surface immunoglobulin M (B-cell receptor) and Toll-like recepto
59 previously unidentified and unique subset of immunoglobulin M(+) B cells that present with an AA4.1(-
60 vation of cells lacking ASF/SF2 through anti-immunoglobulin M-B-cell receptor cross-linking rescued v
61 h Laboratory (VDRL) test and a specific IgM (immunoglobulin M) capture enzyme-linked immunosorbent as
62 en VWF levels < 130 U/dL and both monoclonal immunoglobulin M concentration (mIgMC) and viscosity.
63 urrence with these findings, postvaccination immunoglobulin M concentrations were not significantly i
64 oint swelling and higher anti-B. burgdorferi immunoglobulin M cross-reactive responses than other str
66 -)), CD8-deficient (CD8(-/-)), and secretory immunoglobulin M-deficient (sIgM(-/-)) mice and wild-typ
70 hrough dengue nonstructural protein 1 and/or immunoglobulin M detection, were included in this study
72 an lipopolysaccharide-binding protein (LBP), immunoglobulin M endotoxin core antibodies to lipopolysa
73 -time polymerase chain reaction (RT-PCR) and immunoglobulin M enzyme-linked immunosorbent assay testi
74 n, WNV-specific B cells were not detected by immunoglobulin M enzyme-linked immunospot analysis until
76 ding alpha/beta interferon (IFN-alpha/beta), immunoglobulin M, gammadelta T cells, and complement aga
77 infection (viral nonstructural protein 1 and immunoglobulin M) has greatly simplified laboratory-base
78 ed by inducible bulk expression of secretory immunoglobulin M heavy chain (mu(s)) thanks to the unfol
79 the stability of the alternatively expressed immunoglobulin M heavy chain secretory mRNA is developme
81 BV infection in nine cases of X-linked hyper-immunoglobulin M (hyper-IgM) syndrome who, due to a muta
83 ated transgenic zebrafish in which the major immunoglobulin M (IgM(+)) B-cell subset expresses green
85 MBC) response was mediated by both classical immunoglobulin M (IgM) (IgM(+)CD27(+)) and switched immu
87 uNP) labels functionalized with anti-Mtb LAM immunoglobulin M (IgM) and anti-Mtb LAM IgG respectively
88 ntial for generating acute pathogen-specific immunoglobulin M (IgM) and early IgG, which reduced path
89 nosorbent assays for anti-H. pylori-specific immunoglobulin M (IgM) and IgA established using bacteri
90 hose obtained by BLOTrix analysis of MarBlot immunoglobulin M (IgM) and IgG and by ViraScan analysis
91 immunosorbent assay (ELISA) that can detect immunoglobulin M (IgM) and IgG antibodies in patients wi
94 terize the nanoscale spatial organization of immunoglobulin M (IgM) and IgG BCRs on the surfaces of r
95 gingivalis CPS developed elevated levels of immunoglobulin M (IgM) and IgG in serum that reacted wit
97 GC-dependent immune responses, reduces total immunoglobulin M (IgM) and IgG levels, and leads to incr
98 eatures, including continuous high titers of immunoglobulin M (IgM) and IgG reactivity throughout all
99 ssociated with higher brain CFU, lower serum immunoglobulin M (IgM) and IgG responses to glucuronoxyl
100 ocococcal pulmonary infection elicited serum immunoglobulin M (IgM) and IgG to the capsular polysacch
103 components of humoral immunity, particularly immunoglobulin M (IgM) and IgG, have critical roles in p
104 /-) mice produced low levels of WNV-specific immunoglobulin M (IgM) and IgG, viral clearance from the
106 se sensitivity and permit the measurement of immunoglobulin M (IgM) and immunoglobulin G (IgG) classe
108 ral immune response to NiV by virus-specific immunoglobulin M (IgM) and immunoglobulin G (IgG) enzyme
110 ) enzyme-linked immunosorbent assay (ELISA), immunoglobulin M (IgM) and immunoglobulin G (IgG) Wester
111 lyzed for (1) viral DNA loads, (2) anti-B19V immunoglobulin M (IgM) and immunoglobulin G (IgG), (3) a
112 gy prior to termination showed both specific immunoglobulin M (IgM) and immunoglobulin G (IgG), where
113 a positive correlation between BA plasma CMV immunoglobulin M (IgM) and liver T-cell CMV reactivity w
114 rated reporter and two endogenous rat genes, Immunoglobulin M (IgM) and Rab38, we demonstrate that a
115 y to such xenobiotics would be predominantly immunoglobulin M (IgM) and using sera from a large cohor
120 We measured PS immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies in Malaysian patients
121 the identification of rubella virus-specific immunoglobulin M (IgM) antibodies in serum, but approxim
122 athies associated with persistently elevated immunoglobulin M (IgM) antibodies that react with GQ1b,
123 of persons with suspected HEV was tested for immunoglobulin M (IgM) antibodies to HEV to confirm infe
125 tected SARS-CoV-2 immunoglobulin G (IgG) and immunoglobulin M (IgM) antibodies was undertaken under m
126 day prior to the onset of clinical disease; immunoglobulin M (IgM) antibodies were detected at low l
128 shown to induce the production of anti-oxLDL immunoglobulin M (IgM) antibodies, due to molecular mimi
131 eguides for the detection of dengue-specific immunoglobulin M (IgM) antibody, and we demonstrate dete
132 ing-mouse brain WN virus antigen used in the immunoglobulin M (IgM) antibody-capture and indirect IgG
134 onstructural protein 1 (NS1) in the standard immunoglobulin M (IgM) antibody-capture enzyme-linked im
136 enzyme or crude lysates generated from anti-immunoglobulin M (IgM) antibody-treated RAMOS cells.
138 , we report that ST6Gal-I deficiency induces immunoglobulin M (IgM) antigen receptor endocytosis in t
139 ed by a selective pressure to retain surface immunoglobulin M (IgM) BCR despite an active class-switc
140 Between 5- and 10-fold more purified human immunoglobulin M (IgM) but not IgG was deposited onto ds
141 ptor for the crystallizable fragment (Fc) of immunoglobulin M (IgM) can function as a cell-surface re
143 y of undetermined significance (MGUS) of the immunoglobulin M (IgM) class, which progresses to lympho
144 lso displayed low Ki-67, CD49d, cell-surface immunoglobulin M (IgM) expression and IgM-signaling resp
146 Passive transfer of normal mouse serum, immunoglobulin M (IgM) from normal mouse serum, or IgG f
148 rpretation of positive cytomegalovirus (CMV) immunoglobulin M (IgM) in the first trimester of pregnan
150 previously demonstrated that clustering the immunoglobulin M (IgM) isotype of BCR with an artificial
152 significantly higher and the endotoxin core immunoglobulin M (IgM) level lower in cases, compared wi
155 l centers (GCs), yet it generates protective immunoglobulin M (IgM) memory B cells (MBCs) that expres
158 lved in the pathogenesis of premalignant non-immunoglobulin M (IgM) monoclonal gammopathy of undeterm
160 detect human parvovirus B19 (B19V)-specific immunoglobulin M (IgM) or IgG in the sera of 198 pregnan
162 enstrom macroglobulinemia (WM), which has an immunoglobulin M (IgM) paraproteinemia, is classified as
163 antibody library obtained from a human donor Immunoglobulin M (IgM) pool was determined to be at leas
164 % CI: 0.7-4.7%) for Epstein-Barr virus (EBV) immunoglobulin M (IgM) positivity, 94.7% (95% CI: 90.7-9
165 Both up-regulation of CD22 expression and immunoglobulin M (IgM) production, markers of CLL differ
166 lymphoma characterized by hypersecretion of immunoglobulin M (IgM) protein and tumor infiltration in
169 (>/=7 days), respiratory manifestations, an immunoglobulin M (IgM) response in peripheral blood, and
171 cked VN activity; moreover, purified natural immunoglobulin M (IgM) restored VN activity to antibody-
174 infections and rule out misleading positive immunoglobulin M (IgM) results in areas with various lev
181 ompared the results of a serum-based measles immunoglobulin M (IgM) test with results of tests using
184 1) integrins reduced B. burgdorferi-specific immunoglobulin M (IgM) titers, enhanced pathogen burden,
186 t assay (ELISA) for the detection of chicken immunoglobulin M (IgM) to WN virus was developed, standa
187 re to oral pathogens was determined by fetal immunoglobulin M (IgM) umbilical cord seropositivity.
188 In Yaounde, Cameroon, parasite-specific immunoglobulin M (IgM) was detected in 14% of cord blood
189 globulinemia (MC), a monoclonal expansion of immunoglobulin M (IgM)(+) autoreactive B cells, and also
190 these primary immunodeficiencies have fewer immunoglobulin M (IgM)(+)IgD(+)CD27(+) B cells, a popula
191 V(+)MC(+) subjects have clonal expansions of immunoglobulin M (IgM)(+)kappa(+)IgD(low/-)CD21(low)CD27
192 Levels of total immunoglobulin G (IgG), immunoglobulin M (IgM), and IgG subtypes against the fol
193 a direct relationship between surface CD79B, immunoglobulin M (IgM), and IgM-induced signaling levels
194 kin lymphoma that features overproduction of immunoglobulin M (IgM), clearly has a familial component
195 des stercoralis was shown to be dependent on immunoglobulin M (IgM), complement activation, and granu
198 enzyme-linked immunospot assay, we evaluated immunoglobulin M (IgM), IgA, and IgG antibody-secreting
199 serum or plasma samples were tested for WNV immunoglobulin M (IgM), IgA, and IgG by using enzyme-lin
201 All animals had high prechallenge levels of immunoglobulin M (IgM), IgG, IgG1, and IgG2 serum antibo
203 , as well as higher concentrations of plasma immunoglobulin M (IgM), relative to individuals with the
204 WM) is characterized by an overproduction of immunoglobulin M (IgM), which can lead to a hyperviscosi
209 cretory antigen (TESA) blot for detection of immunoglobulin M (IgM)-specific shed acute phase antigen
210 on of EBV latency III LCL gene expression to immunoglobulin M (IgM)-stimulated B cells, germinal-cent
215 tion in bone marrow, lymph node development, immunoglobulin M (IgM)/IgG production, and humoral immun
217 58.95; P = .001) and high levels of phase II immunoglobulin M (IgM; AHR, 6.59; 95% CI, 1.37-31.62; P
218 further into the immune response by studying immunoglobulin-M (IgM) and IgG subclass 3 (IgG3) DSA to
219 the mechanisms behind WM transformation from immunoglobulin-M (IgM) monoclonal gammopathy of undeterm
220 itudinal dynamics of immunoglobulin-G (IgG), immunoglobulin-M (IgM), and in vitro neutralizing antibo
221 njugates, but the Inaba-specific antibodies (immunoglobulin M [IgM] and IgG1) were neither vibriocida
222 mice produced human monoclonal paraprotein (immunoglobulin M [IgM] and/or kappa or lambda chain) det
223 (chronic ataxic neuropathy, ophthalmoplegia, immunoglobulin M [IgM] paraprotein, cold agglutinins, an
224 resistance of monoclonal antibodies B6.1 (an immunoglobulin M [IgM]) and C3.1 (an IgG3) against exper
225 e same HA copy number), the highest primary (immunoglobulin M [IgM]) and secondary (IgG) anti-HA humo
227 use mice (transgenic mice that express human immunoglobulin M [IgM], IgG2, and kappa) which were immu
228 three populations: somatically hypermutated immunoglobulin M(+) (IgM(+)) and IgG(+) MBC subsets and
233 re stained for galactose-alpha1,3-galactose, immunoglobulin M, immunoglobulin G, complement, fibrin,
234 l enzyme-linked immunosorbent assay kits for immunoglobulin M/immunoglobulin G antibodies to herpes s
235 globulins enriched with immunoglobulin A and immunoglobulin M improve the integrity of the blood-brai
239 detectable levels of immunoglobulin G and/or immunoglobulin M in human plasma samples after treatment
240 In Gp1, anti-A/B and cytotoxic anti-pig immunoglobulin-M increased steadily during the first yea
244 s and secreting Stx1-specific Hu-MAbs (seven immunoglobulin M(kappa)() [IgM(kappa)] elements [one spe
245 8 pneumococcal capsular polysaccharide D11 [immunoglobulin M(kappa)] protects wild-type and compleme
246 h nonsense CXCR4 mutations have higher serum immunoglobulin M levels and incidence of symptomatic hyp
247 munity were associated with persistently low immunoglobulin M levels and lymphopenia, respectively.
248 w lower bone marrow disease burden and serum immunoglobulin M levels but show an increased risk of de
249 declined from 55% to 10% (P = .0004), serum immunoglobulin M levels declined from 4,830 to 1,115 mg/
250 bone marrow (BM) disease involvement, serum immunoglobulin-M levels, and symptomatic disease requiri
251 WILDTYPE (WT)) had intermediate BM and serum immunoglobulin-M levels; those with MYD88(WT)CXCR4(WT) s
252 enes (>5% deviation from germ line), surface immunoglobulin M ligation failed to induce receptor tran
253 derly individuals have a lower percentage of immunoglobulin M memory B cells than healthy young adult
254 t expression of the secretory heavy chain of immunoglobulin M (micros), is well-tolerated in HeLa cel
256 DS Eligible patients had measurable disease (immunoglobulin M monoclonal protein > 1,000 mg/dL with >
257 mpared to those for a cohort of B19-specific immunoglobulin M-negative (IgM(-)), IgG(+) remotely infe
258 lored whether the presence of lipid-specific immunoglobulin M oligoclonal bands in cerebrospinal flui
259 globulins enriched with immunoglobulin A and immunoglobulin M on blood-brain barrier integrity and su
266 ients had significant increase in polyclonal immunoglobulin M (P = .005), indicating innate immune sy
267 rom their original discovery 20 years ago in immunoglobulin M paraproteinaemic neuropathy through to
269 based on seroconversion for HCMV and/or HCMV immunoglobulin M-positive and low or moderate HCMV immun
271 s (P < 0.05) were evident in CD4(+), CD8(+), immunoglobulin M-positive, and CD172a(+) cell fractions
277 >/=0.2 g/24 h), absence of intact monoclonal immunoglobulin (M protein) in the serum, and no evidence
285 erm persistence of anti-viral capsid antigen immunoglobulin M responses in children from the high-mal
287 versus postoutbreak sample, and near-farm by immunoglobulin M seroprevalence in a municipal populatio
288 B cells from apoptosis and increases surface immunoglobulin M (sIgM) expression on murine splenic B c
289 ates of anergy, indicated by reduced surface immunoglobulin M (sIgM) levels and signaling, consequent
290 ivation also correlated closely with surface immunoglobulin M (sIgM) signaling capacity in vitro in b
291 ps infection can be made by the detection of immunoglobulin M-specific antibodies to mumps virus in a
292 intracellular calcium that accompanies anti-immunoglobulin M stimulation, and this effect mediates t
293 TFE3 and TFEB in T cells resulted in a hyper-immunoglobulin M syndrome due to impaired expression of
296 globulins enriched with immunoglobulin A and immunoglobulin M treatment, no ultrastructural evidence
298 produced immunoglobulin G predominantly, but immunoglobulin M was predominant in younger children.
299 ain, immunoglobulin G, immunoglobulin A, and immunoglobulin M were measured on ICU days 1, 3, and 7.
300 in ZAP-70-positive CLL trigger secretion of immunoglobulin M, which then serves as (auto-) antigen f