ライフサイエンスコーパス: immunoglobulin class switching

1 ly feeble which is attributed to inefficient immunoglobulin class switching.

2 tions, which support affinity maturation and immunoglobulin class switching.

3 in increased AID accumulation and increased immunoglobulin class switching.

4 eavy-chain (Igh) locus, leading to defective immunoglobulin class switching.

5 ble-strand break consistent with an error in immunoglobulin class switching.

6 antibody titers and demonstrated evidence of immunoglobulin class switching.

7 lls, antigen-specific human CD8 T cells, and immunoglobulin class switching.

8 tokines, and their B cells could not undergo immunoglobulin class switching.

9 creting CD4 T and CD8 T cells, or to undergo immunoglobulin class switching.

10 D40-mediated NF-kappaB activation for B cell immunoglobulin class-switching.

11 o differentiation, somatic hypermutation and immunoglobulin class switching and exhibit a more activa

12 he classical, NF-kappaB pathway, it promoted immunoglobulin class switching and generation of pathoge

13 f immunoglobulin deposition argued for local immunoglobulin class switching and ongoing production.

14 ghts into the function of Tet3 in TFH-driven immunoglobulin class switching and suggest a new approac

15 Similar immunoglobulin class-switching and somatic hypermutation

16 ized by recurrent infections due to impaired immunoglobulin class-switching and somatic hypermutation

17 tive proliferation during B cell activation, immunoglobulin class switching, and as a result GC forma

18 ation of basophils and mast cells, promoting immunoglobulin class switching, and preventing excessive

19 ovides an important costimulatory signal for immunoglobulin class switching, antibody affinity matura

20 Also, IgM and IgG1 antibody production and immunoglobulin class switching are not affected.

21 onjugate was immunogenic in mice and induced immunoglobulin class switching as well as affinity matur

22 Blimp-1 also inhibited immunoglobulin class switching by blocking expression of

23 utoreactive B-cell population, inhibition of immunoglobulin class switching, decreased frequency and

24 xaminations of T- and B-cell development and immunoglobulin class switching did not reveal a defect i

25 Immunoglobulin class switching from IgM to IgG in respon

26 Immunoglobulin class switching from immunoglobulin M (Ig

27 D) is required for somatic hypermutation and immunoglobulin class switching in activated B cells.

28 d decrease in NHEJ is insufficient to impact immunoglobulin class switching in DEK knockout mice.

29 f follicular B cells in the meninges, and of immunoglobulin class switching in the cerebrospinal flui

30 itical role in germinal center formation and immunoglobulin class switching in vivo.

31 ved impaired IL-21-induced proliferation and immunoglobulin class-switching in B cells, cytokine prod

32 lymphocytes that promotes proliferation and immunoglobulin class-switching in B cells.

33 characteristic of a Th2 influence on B cell immunoglobulin class-switching in the IL-10 Tg group.

34 From humans to frogs, immunoglobulin class switching introduces different effe

35 Immunoglobulin class switching is crucial for the genera

36 The inability of A2 mice to undergo immunoglobulin class switching is due to deficient CD4 h

37 Immunoglobulin class switching is mediated by recombinat

38 otype in B cells and supports a controllable immunoglobulin class-switching reaction.

39 ivo capacity to induce B cell maturation and immunoglobulin class switching than cells from HIV progr

40 BRCA1-null cells, end-joining activity, and immunoglobulin class switching that rely on 53BP1.

41 emGFP(+) germinal center B cells undergoing immunoglobulin class switching to express IgG and their

42 ion, expression of cell surface markers, and immunoglobulin class switching to IgE.

43 es IL-4 and lipopolysaccharide-driven B-cell immunoglobulin class switching to IgE.

44 ilia, alternative macrophage activation, and immunoglobulin class switching to IgG1, were enhanced in

45 munized with MUC1 peptides failed to exhibit immunoglobulin class switching to the IgG subtypes.

46 STAT6 mediate T(H)2 responses in T cells and immunoglobulin class-switching to IgE in B cells.

47 histories, somatic hypermutation (SHM), and immunoglobulin class-switching was performed.

48 Both lymphocyte development and immunoglobulin class switching, which rely on the genera

49 es with B cells undergoing cytokine-specific immunoglobulin class switching with evidence of somatic