ライフサイエンスコーパス: immunological memory

1 g, affinity maturation, and the induction of immunological "memory".

2 and sustain multifaceted SARS-CoV-2-specific immunological memory.

3 D-L1 therapy, and establishes tumor-specific immunological memory.

4 thogens and provide the host with protective immunological memory.

5 or responses as well as the establishment of immunological memory.

6 ls, demonstrating that Ag-anti-CD180 induces immunological memory.

7 gical functions ranging from inflammation to immunological memory.

8 ion was T cell dependent and elicited potent immunological memory.

9 tion, cytokine production, and generation of immunological memory.

10 rsist by exploiting the cellular vehicles of immunological memory.

11 ts in the formation of adaptive immunity and immunological memory.

12 racterized by the ability to form long-lived immunological memory.

13 lting in antibodies of low affinity and poor immunological memory.

14 mune responses showed the installation of an immunological memory.

15 s well as the development and maintenance of immunological memory.

16 iparum responses, suggesting the presence of immunological memory.

17 ccines, adjuvants play a key role in shaping immunological memory.

18 expansion, and development of virus-specific immunological memory.

19 at was required for the persistence of local immunological memory.

20 ion of innate and adaptive responses and for immunological memory.

21 t of adaptive immunity and the generation of immunological memory.

22 cytes, pathogen clearance, and generation of immunological memory.

23 encounter with a pathogen; an ability termed immunological memory.

24 nst malaria and other pathogens that disrupt immunological memory.

25 This is despite the demonstrable presence of immunological memory.

26 for each subset, reflecting unique roles in immunological memory.

27 , DC subsets can shape adaptive immunity and immunological memory.

28 ta T cells and CD4+ T cells, and (iii) lacks immunological memory.

29 he foundation for T cell differentiation and immunological memory.

30 antibody may interfere with the induction of immunological memory.

31 to involve tumor-specific CTL and protective immunological memory.

32 ) response to antigen and the maintenance of immunological memory.

33 tive generation and preservation of specific immunological memory.

34 um IgG and mucosal IgA responses and induced immunological memory.

35 fic CD8+ T cells are central to the study of immunological memory.

36 and humoral immunity as well as long-lasting immunological memory.

37 eriphery and may function as a repository of immunological memory.

38 ective immune response with the induction of immunological memory.

39 potential contributions of B cell subsets to immunological memory.

40 ne responses leading to tumor regression and immunological memory.

41 tical to understanding the cellular basis of immunological memory.

42 isotype switching, T cell costimulation, and immunological memory.

43 ar of life was evaluated for the presence of immunological memory.

44 quent immune responses and to participate in immunological memory.

45 t mean for the generation and maintenance of immunological memory.

46 suggests that they play a role in protective immunological memory.

47 and led to the generation of tumor-specific immunological memory.

48 ms consistent with the purpose of evidencing immunological memory.

49 D-2HG inhibition elicited anti-mIDH1 glioma immunological memory.

50 ecuted by cytotoxic T lymphocytes and elicit immunological memory.

51 ated with an antibody response indicative of immunological memory.

52 ity clones are also known to expand and form immunological memory.

53 ole in the long-term survival of T cells and immunological memory.

54 RM)) have emerged as essential components of immunological memory.

55 lenge, consistent with conferment of lasting immunological memory.

56 ovided effective tumor control and long-term immunological memory.

57 diated by tumor-specific T cell immunity and immunological memory.

58 e-challenge, indicating the establishment of immunological memory.

59 glioma immunity, leading to increased MS and immunological memory.

60 andscape, indicative of the establishment of immunological memory.

61 sm governing T cell subset specification and immunological memory.

62 tudies confirmed the establishment of robust immunological memory.

63 s but lack the capacity to develop classical immunological memory.

64 to lack antigen specificity and be devoid of immunological memory.

65 partment as a potential major contributor to immunological memory.

66 prime the immune system to develop anti-GBM immunological memory.

67 nt T cells in vitro, suggesting long-lasting immunological memory.

68 i-CTLA-4 Ab to achieve tumor eradication and immunological memory.

69 , thereby providing the host with long-lived immunological memory.

70 processes as a form of defense or to promote immunological memory.

71 res of established tumors and development of immunological memory.

72 ic changes are crucial for the generation of immunological memory.

73 the host of virus and builds virus-specific immunological memory.

74 te to tonic cellular activation and maintain immunological memory.

75 mune responses resulting in antigen-specific immunological memory.

76 ction for Cas9 in the genesis of prokaryotic immunological memory.

77 om foreign DNAs into CRISPR loci to generate immunological memory.

78 as recently been shown to improve CD8 T cell immunological memory.

79 t their mothers with new pregnancy-imprinted immunological memories.

80 thus reveal Cas9's role in the generation of immunological memories.

81 s spacers, are stored in the CRISPR array as immunological memories.

82 pecific clonal proliferation and to generate immunological memory(1-3).

83 The developmental requirements for immunological memory, a central feature of adaptive immu

84 ne cells might also be capable of developing immunological memory, a trait previously associated with

85 trigger the mechanisms necessary to generate immunological memory able to induce long-term protection

86 Markers of immunological memory, activation, and proliferation were

87 vant novel players in the diversification of immunological memory after allogeneic HSCT.

88 The magnitude, quality, and maintenance of immunological memory after infection or vaccination must

89 ent cell death results in the persistence of immunological memory after TBI and can explain the immun

90 on of complete vaccinees may have lost their immunological memories against HBsAg.

91 f serum anti-toxin activity, and a marker of immunological memory against anthrax.

92 -specific Vgamma4 cells function in adaptive immunological memory against B. pertussis.

93 ting in cure of some mice and development of immunological memory against B78 and wild type B16 tumor

94 to promote brain tumor regression and induce immunological memory against glioma.

95 udies of successive vaccination suggest that immunological memory against past influenza viruses may

96 Generation of potent immunological memory against rechallenge in cured mice a

97 conjugate vaccines (PCV10 and PCV13) induce immunological memory against Streptococcus pneumoniae in

98 No T cell-mediated immunological memory against the parental tumor was gene

99 cure large established tumors and to confer immunological memory against tumor cells, although a con

100 The mice cured from ReACT also developed immunological memory against tumor rechallenge.

101 and the advanced adaptive arm that generates immunological memory, allowing rapid, specific recall re

102 ablished melanomas, induced antigen-specific immunological memory and controlled tumour growth in a g

103 SCs, cTfh, MBCs, and CD4+ T cells to enhance immunological memory and establish long-term vaccine-ind

104 Parasite-induced subversion of immunological memory and expansion of "atypical" memory

105 ctive adaptive immunity are distinguished by immunological memory and high-affinity antigen recogniti

106 derstanding of the duration and magnitude of immunological memory and how it relates to protective im

107 a actively interfere with the development of immunological memory and may account for the evolutionar

108 n remain in the body for years, thus forming immunological memory and potentially mappable immunologi

109 te a novel mechanism by which IFN-I regulate immunological memory and provide insights for rational v

110 increased animal survival, and to long-term immunological memory and systemic immune surveillance, w

111 pulate this process to increase the level of immunological memory and thus, vaccine efficacy.

112 for the generation of high-affinity Abs and immunological memory and, therefore, are critical for th

113 of a T-cell-dependent response that elicits immunological memory and, therefore, primes the immune s

114 une compartments critical for hematopoiesis, immunological memory, and bone regeneration.

115 ork on our understanding of the formation of immunological memory, and describe a number of unresolve

116 mple explanation for lymphocyte specificity, immunological memory, and elimination of self-reactive c

117 cited antigen-specific adaptive immunity and immunological memory, and inhibited tumour growth, metas

118 lular signals involved in the development of immunological memory, and the relative contributions of

119 h response dynamics suggest the influence of immunological memory, and understanding how this process

120 d dogmas: (1) only adaptive immunity confers immunological memory; and, (2) innate immunity lacks spe

121 Because tumor destruction and formation of immunological memory are ultimately T-cell-mediated effe

122 Some immune components, such as immunological memory, are intrinsically programmable.

123 uced systemic cytotoxic T-cell responses and immunological memory associated with tumour regression a

124 This is the first demonstration of immunological memory at 4 years of age in children recei

125 echanisms responsible for the development of immunological memory at the cellular level, however.

126 t is not known whether these vaccines induce immunological memory at the mucosal level, which may be

127 adaptive Q9-restricted CTL response leads to immunological memory, because mice that resist the initi

128 A separate study explored immunological memory both in subjects who had received C

129 a cytotoxic immune response and induction of immunological memory by inhibiting secondary tumor growt

130 as adaptive immune systems(1), which provide immunological memory by inserting short DNA sequences fr

131 rapy and further suggest that maintenance of immunological memory by MHC class II-expressing ECs via

132 NLRC4 negatively regulates immunological memory by preventing delayed activation of

133 itochondrial autophagy in the maintenance of immunological memory by protecting the metabolic quiesce

134 nriched further by studies on whether recent immunological memory can 'overfill' and/or constrict pri

135 Immunological memory can be defined as the faster and st

136 Finally, immunological memory can be generated, allowing for erad

137 How long immunological memory can be maintained in the absence of

138 Immunological memory can develop from multiple branches

139 s well as the determinants of recruitment to immunological memory, can greatly contribute to our basi

140 patient's own individual tumor, that through immunological memory, can result in long-lasting systemi

141 inical infections, such as poor induction of immunological memory cells and inefficient T effector ce

142 ttle between reemergent infectious virus and immunological memory cells provides an essential virus-h

143 of high-affinity, isotype-switched Abs, and immunological memory; consequently, many infections requ

144 Although B and T cell immunological memory contribute to protective immunity t

145 Immunological memory crucially depends on CD4 T cells.

146 lood can provide important information about immunological memory, CTL responses against tumour antig

147 munity, associated with long-term protective immunological memory, defines the efficacy of a given va

148 Immunological memory depends on a self-renewing pool of

149 Immunological memory depends on the long-term maintenanc

150 meostasis, the germinal center reaction, and immunological memory, developing recombinase-assisted an

151 re are many gaps in our understanding of how immunological memory develops following M. tuberculosis

152 Little is known on whether immunological memory develops following pH1N1 infection

153 Furthermore, immunological memory develops under cover of CD40L block

154 The prevailing evidence suggests that immunological memory does not require antigenic re-stimu

155 strated that exposure to TLR ligands induces immunological memory driven by changes in hematopoietic

156 mental host strategy to sustain and optimize immunological memory during nutritional challenges that

157 Immunological memory exists so that following infection

158 gical factors that govern the maintenance of immunological memory following exposure to M. tuberculos

159 high nAb titers support presence of durable immunological memory following primary MVA-BN immunizati

160 Understanding immunological memory formation depends on elucidating ho

161 Our studies show that immunological memory generated during youth functions we

162 ofile, sustained therapeutic response due to immunological memory generation, and effectiveness acros

163 t tumor re-challenge, indicating anti-cancer immunological memory generation.

164 The cellular basis of immunological memory has been a debated issue.

165 ing effects on priming versus development of immunological memory has been challenging.

166 Immunological memory has been linked with the adaptive f

167 Maintenance of immunological memory has been proposed to rely on stem-c

168 The existence of immunological memory has been recognized for over 2,000

169 Immunological memory has long considered to be harbored

170 l view that only adaptive immunity can build immunological memory has recently been challenged.

171 Immunological memory has traditionally been regarded as

172 Immunological memory has traditionally been regarded as

173 o specifically kill glioma cells and develop immunological memory have shown remarkable progress.

174 Unfortunately, owing to an inefficient immunological memory, hMPV infection provides limited im

175 ptive immunity leads to the establishment of immunological memory; however, how innate immunity regul

176 Specific Abs and immunological memory imply that Ab diversification and c

177 traits of adaptive immunity and can acquire immunological memory in a manner similar to that of T an

178 Immunological memory in adaptive and innate immune cells

179 signatures could facilitate surveillance of immunological memory in communities.

180 y avidity maturation, isotype switching, and immunological memory in immunized neonates.

181 this review is to summarize the evidence for immunological memory in lower organisms (which are not t

182 Nevertheless, there is evidence of immunological memory in lower organisms and invertebrate

183 ous antitumor immunity with the formation of immunological memory in murine tumor models and robust a

184 ceptibility is due to the virtual absence of immunological memory in newborns.

185 ed the long-term persistence of antibody and immunological memory in primary-school children followin

186 nisms governing the long-term persistence of immunological memory in response to vaccines remain uncl

187 K and Ad-Flt3L) elicits tumor regression and immunological memory in rodent GBM models.

188 hat this priming mechanism may contribute to immunological memory in T cells by facilitating the indu

189 These data indicate a potential role for immunological memory in the dynamics of HA and NA antibo

190 cribed to have the unique capacity to confer immunological memory in the form of hapten-specific cont

191 brates, insects use immune cells to generate immunological memory in the form of stable vDNAs that ge

192 oreover, the combinatorial treatment elicits immunological memory in the Pten-null prostate cancer mo

193 ssibility that EVEs may serve as a source of immunological memory in these organisms.

194 plete tumour regression and the formation of immunological memory in tumour rechallenge models.

195 Immunological memory in vertebrates is often exclusively

196 + T cells that underlie antiviral protective immunological memory in vivo is unclear.

197 Immunological memory is a cardinal feature of adaptive i

198 Immunological memory is a composite of lasting antibody

199 Long-lasting immunological memory is a core feature of the adaptive i

200 Immunological memory is a defining feature of immunity,

201 Immunological memory is a defining feature of vertebrate

202 Immunological memory is a fundamental function of vaccin

203 Immunological memory is a hallmark of adaptive immunity,

204 Immunological memory is a hallmark of the adaptive immun

205 Immunological memory is an exclusive property of the acq

206 Immunological memory is characterized by the ability to

207 Immunological memory is critical for immune protection,

208 Immunological memory is defined by the ability of a host

209 of patients could be improved, assuming that immunological memory is effectively controlled with immu

210 irus proteins that modulate the induction of immunological memory is important for improving virus-ba

211 The mechanisms by which immunological memory is maintained after infection or va

212 Mathematical modeling reveals that long-term immunological memory is maintained in a manner that is e

213 nd regulated, its role in pathology, and how immunological memory is maintained.

214 promoting autophagy to improve Ab-dependent immunological memory is more effective during memory B c

215 ts with a current infection, suggesting that immunological memory is not induced by uncomplicated gon

216 Immunological memory is one of the central features of t

217 ism by which B. melitensis subverts adaptive immunological memory is poorly understood.

218 Rabies immunological memory is reactivated within 7 days after

219 Immunological memory is required for protection against

220 The evolution of immunological memory is subject to debate.

221 A hallmark of immunological memory is the ability of previously primed

222 Immunological memory is the ability of the immune system

223 Immunological memory is the basis of protective immunity

224 Generation and maintenance of protective immunological memory is the goal of vaccination programs

225 Long-lasting immunological memory is the ultimate goal of vaccination

226 Immunological memory is the underlying mechanism by whic

227 Immunological memory is thought to depend on a stem cell

228 The purpose of immunological memory is to protect the host from reinfec

229 Evidence is emerging that this immunological memory is underpinned by dynamic changes a

230 ime of neutrophils, their ability to acquire immunological memory may lie in the central training of

231 Immunological memory (MEM) development is affected by st

232 ion from tumor rechallenges, consistent with immunological memory not otherwise achievable.

233 Priming is a major mechanism behind the immunological 'memory' observed during two key plant sys

234 uding bacteriophages, by recording DNA-based immunological memories of infection called "spacers." Ho

235 an adaptive defense mechanism that acquires immunological memories of infections.

236 The CRISPR integrases Cas1-Cas2 create immunological memories of viral infection by storing pha

237 curs, and what processes are involved in the immunological memory of allergen-specific IgE responses.

238 nition of specific protein antigens leads to immunological memory of antigen, whereas recognition of

239 egulation is proposed in which a nonspecific immunological memory of danger accumulates during matura

240 Our observations indicate that immunological memory of dengue serotypes occurs at the n

241 The utility of probing immunological memory of infections is demonstrated by de

242 CD8(+) T cell immunological memory of past antigen exposure can confer

243 ific desensitization and result in a form of immunological memory of prior stimulation.

244 e immune responses and, although lacking the immunological memory of vertebrate adaptive immunity, sh

245 cularly in those where there is pre-existing immunological memory or in those receiving T-cell deplet

246 n is currently available regarding prolonged immunological memory post-RABV vaccination.

247 Long-term survivors developed immunological memory, preventing pHGG growth upon rechal

248 ong-lived cells that form a critical part of immunological memory, providing rapid antibody responses

249 , we propose that DR-induced optimization of immunological memory requires a complex cascade of event

250 Characterising the longevity of immunological memory requires establishing the rules und

251 The generation and maintenance of immunological memory requires the activation, expansion,

252 It appears an immunological memory response is elicited with these rep

253 Generation of a robust immunological memory response is essential for protectio

254 t the codelivery system produced a long-term immunological memory response to prevent tumor recurrenc

255 pt to understand the molecular basis for the immunological memory response, we have used cDNA microar

256 wing infection, and also impairs preexisting immunological memory, resulting in "immune amnesia" that

257 Immunological memory specific to previously encountered

258 e propose a model of T cell memory, in which immunological memory state is encoded epigenetically, th

259 ysis of metabolic transcriptome confirms the immunological memory status of KIR(+)CD56(+) T cells in

260 innate immunity by a newly described form of immunological memory termed "trained immunity." An LAV d

261 ection induced a long-lasting enhancement of immunological memory that conferred improved protection

262 ansplantation, and explore the properties of immunological memory that contribute to allograft reject

263 Our model offers a new insight into immunological memory that could assist the development o

264 ssing 3LLA9F1 or RMA tumor cells established immunological memory that enhanced protection against su

265 immune checkpoint blockade and induction of immunological memory that protects against tumour rechal

266 To generate immunological memory, the Cas1-Cas2 protein complex capt

267 contribute to the maintenance and waning of immunological memory, the following study examined the f

268 a new force that can drive the evolution of immunological memory: the duration of memory can regulat

269 the immune system is to maintain protective immunological memory to a wide variety of pathogens enco

270 SPR-Cas systems enables the generation of an immunological memory to defend against invading viruses.

271 These data show that immunological memory to DryVax vaccine is long-lived and

272 ection, the host T cell compartment develops immunological memory to ensure rapid responses upon re-i

273 Y just after thymectomy continued to display immunological memory to H-Y for >1 year.

274 Most children vaccinated at birth retain immunological memory to hepatitis B vaccine for 15 years

275 ulation of memory cell states and harnessing immunological memory to improve immunotherapies.

276 erated significant interest in understanding immunological memory to influenza and how previous encou

277 tive costimulatory pathways for induction of immunological memory to influenza virus.

278 Immunological memory to pathogens is associated with clo

279 the concept that stimulation of preexisting immunological memory to Pneumocystis with a recombinant

280 r growth, as well as building long-term host immunological memory to prevent tumor recurrence.

281 ans and dogs residing in Tbilisi have little immunological memory to saliva of P. kandelakii, the pri

282 ODSWe performed a longitudinal evaluation of immunological memory to SARS-CoV-2 up to 1 year after in

283 Immunological memory to seasonal influenza was establish

284 fluenza virus strain was so virulent and how immunological memory to the 1918 virus may have shaped t

285 Immunological memory to vaccination and viral infection

286 uality of humoral immunity and generation of immunological memory to vaccines is critical for protect

287 ciated with diabetes, can build nonspecific, immunological memory (trained immunity) via epigenetic r

288 d immunosuppression, and to induce long-term immunological memory, understanding of the multiple regu

289 TLR7(-/-) mice failed to develop protective immunological memory upon challenge.

290 c methods to characterize the development of immunological memory, vaccination, and other processes t

291 the potential of EVEs to serve as sources of immunological memory via the piRNA pathway may be genera

292 Historically, immunological memory was considered an exclusive feature

293 Immunological memory was rapidly recalled by booster vac

294 Immunological memory was rapidly recalled by booster vac

295 emingly essential for high-affinity, cognate immunological memory, whereas gammadelta cells contribut

296 vailable regarding the mechanisms underlying immunological memory, which can broaden humoral response

297 of vertebrate immunity is the acquisition of immunological memory, which confers enhanced protection

298 n how long infection- or vaccination-induced immunological memory will last.METHODSWe performed a lon

299 he absence of dendritic cells and results in immunological memory with protective effector functions.

300 eving allograft tolerance is the presence of immunological memory within the recipient, which confers