コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
1 apse 24 months after they stopped taking the immunomodulator).
2 mes at 1 year than early monotherapy with an immunomodulator.
3 growing evidence that vitamin D is a potent immunomodulator.
4 ltoheptaose was identified from WG-PS3 as an immunomodulator.
5 a previously unknown function for GP2 as an immunomodulator.
6 f estrogen, a well-known neuroprotectant and immunomodulator.
7 to function as both a primary adhesin and an immunomodulator.
8 -TNF agent and 2676 patients treated with an immunomodulator.
9 ro- and anti-inflammatory properties of this immunomodulator.
10 vealing a potential function of VEGF-C as an immunomodulator.
11 unconventional amino acid ethionine, a known immunomodulator.
12 entified human anti-microbial metabolite and immunomodulator.
13 and is under investigation as a non-specific immunomodulator.
14 new targets for intervention, as well as new immunomodulators.
15 ancer cells and provide sustained release of immunomodulators.
16 new targets for intervention, as well as new immunomodulators.
17 atory destruction in vitro and are promising immunomodulators.
18 iculate vaccines, drug delivery systems, and immunomodulators.
19 s that of a physical linkage between Ags and immunomodulators.
20 mulation from other allergens or copresented immunomodulators.
21 es (such as ATP and UTP) have emerged as key immunomodulators.
22 therapeutically delivering nucleic acids as immunomodulators.
23 could result in more effective vaccines and immunomodulators.
24 to the conserved structural features of HCMV immunomodulators.
25 tentially be developed into orally available immunomodulators.
26 the potential interference of tumor-derived immunomodulators.
27 and may have clinical utility as stand-alone immunomodulators.
28 e receiving BM185 cells expressing all three immunomodulators.
29 ity triggered by systemic delivery of potent immunomodulators.
30 gn and their biological applications such as immunomodulators.
31 plications for the use of CpG-A and CpG-B as immunomodulators.
32 SCs) have been studied for decades as potent immunomodulators.
33 ogic monotherapy vs combination therapy with immunomodulators, (3) comparative efficacy of top-down (
34 lpha was superior to early treatment with an immunomodulator (85.3% vs 60.3% in remission; relative r
37 .05 [95% confidence interval, 1.07-3.93] and immunomodulator adjusted odds ratio, 1.81 [95% confidenc
38 imply as an immunosuppressant, but as a mild immunomodulator, administration of glucosamine provides
39 subcutaneous administration of this defined immunomodulator affords protection against joint disease
40 nts with Crohn's disease who discontinued an immunomodulator after combination therapy found that rat
41 isease (CD) includes early administration of immunomodulators after initial treatment with corticoste
42 f curdlan, a naturally occurring beta-glucan immunomodulator, against visceral leishmaniasis, a fatal
43 ode activation, and skin sensitization using immunomodulators agonistic for a family of sphingosine-1
44 ainst divergent strains, act as adjuvants or immunomodulators, allow for sustained release of antigen
48 al attention as both a Th1-like inflammatory immunomodulator and a pathogenic co-stimulator of autore
49 These results demonstrate that ARID2 is an immunomodulator and a potential biomarker that indicates
50 tor that is being investigated as a targeted immunomodulator and disease-modifying therapy for rheuma
51 P [c-diguanylate]) is a novel small molecule immunomodulator and immunostimulatory agent that trigger
54 in C57BL/6 mice since estrogen is a natural immunomodulator and we have recently reported that estro
55 erate to severe UC often requires the use of immunomodulator and/or biologic therapies, including thi
56 nosalicylates in patients being treated with immunomodulator and/or biologic therapy for moderate to
57 these common sublethal infections may act as immunomodulators and affect population dynamics through
59 tionally, antiepileptic maneuvers may act as immunomodulators and anti-inflammatory therapies can tre
63 r KPro use but studies investigating various immunomodulators and biologic materials for improved ret
68 ors (SCINs) are one important class of these immunomodulators and consist of three active members (SC
70 Our data demonstrate that fungi are potent immunomodulators and have powerful effects on asthma ind
72 -infectives and both microbe- and host-based immunomodulators and their feasibility for use in asthma
73 ions and have implications for the design of immunomodulators and vaccines containing beta-glucans.
74 t approaches favor the early introduction of immunomodulators and/or antitumor necrosis factor (TNF)
76 aminosalicylates, 0.5 (95% CI, 0.3-0.9) for immunomodulators, and 0.8 (95% CI, 0.6-1.1) for corticos
77 (95% CI, 0.5-1.1), 1.3 (95% CI, 0.9-1.9) for immunomodulators, and 1.0 (95% CI, 0.7-1.4) for corticos
78 tion therapy, intratumoural therapies, other immunomodulators, and adaptive cell therapy, including c
79 d use of medications, particularly steroids, immunomodulators, and biological agents; and a high risk
83 steroids, 5-aminosalicylic acid derivatives, immunomodulators, and more recently thalidomide and pent
84 afety of long-term therapy with anti-TNF and immunomodulators, and predictors of relapse following th
85 y or autoimmune disorders), use of potential immunomodulators, and recent use of antibiotics or probi
88 ties of mesalamine, antibiotics, budesonide, immunomodulators, anti-tumor necrosis factor alpha (anti
90 ior; beta-lactam antibiotics can function as immunomodulators, apparently through covalent binding to
91 rophylactic treatment with H. pylori-derived immunomodulators appears to be a promising strategy for
96 ty of the NF-kappaB response to a variety of immunomodulators are mediated by core circadian protein
97 I IFNs and ICSBP, and demonstrate that these immunomodulators are required for the immunoprotective e
98 reduced myeloid-derived suppressor cells and immunomodulators ARG1, CTLA-4, IL-6, IL-10, LAG3, and PD
99 In this study, we show that the helminth immunomodulator AvCystatin, a cysteine protease inhibito
100 The 'step-up' approach includes the use of immunomodulators [azathioprine (AZA), or 6-mercaptopurin
103 s or older with a lower use of biologics and immunomodulators but higher absolute risk of bowel surge
104 D, elderly patients used fewer biologics and immunomodulators but more systemic corticosteroids.
105 uch as interleukins, chemotherapy, and other immunomodulators, but these adjuvant treatments are ofte
106 how one molecule can serve as a double-edged immunomodulator by directing discrete biological consequ
107 r results suggested that HCV NS5A acts as an immunomodulator by inhibiting IFN-gamma production and m
108 nal domain (BET) chromatin adaptors serve as immunomodulators by directly regulating Th17 responses a
111 mune responses by introducing genes encoding immunomodulators (CD40 ligand (CD40L), CD80, and GM-CSF)
113 after treatment (19% after TNF and 17% after immunomodulators) compared with fit patients (9% after T
114 tly since the introduction of infliximab, an immunomodulator considered particularly effective in tre
115 have revealed that osteopontin, an important immunomodulator, contributes to the increased amounts of
116 As an oncoprotein as well as a potential immunomodulator, controlling SHP2 activity is of high th
117 cer-related diseases, as well as a potential immunomodulator, controlling SHP2 activity is of signifi
118 ibiting CD28 costimulation with the approved immunomodulator CTLA4Ig suppressed primary responses in
120 uction] of immunomodulator monotherapy, 8 on immunomodulator de-escalation from combination therapy,
127 zMPC, a novel probiotic product, is a potent immunomodulator for macrophages and may be beneficial fo
128 -tumor necrosis factor (TNF) agent and/or an immunomodulator for patients with inflammatory bowel dis
129 leukin-7 (IL-7) is a prospective therapeutic immunomodulator for the treatment of HIV, we evaluated t
130 ficial; here, we discovered that FTY-720, an immunomodulator for treating multiple sclerosis, can rev
131 e available in recent years, such as topical immunomodulators for atopic dermatitis, leukotriene anta
132 ory in current clinical trials using several immunomodulators for boosting antiviral immunity, immuno
134 a single agent and in combination with other immunomodulators for inhibition of T-cell proliferation
135 e of ribavirin (alone or in combination with immunomodulators) for the treatment of respiratory syncy
136 igated the therapeutic efficacy of the novel immunomodulator FTY720 (Fingolimod), alone and in combin
140 receiving BM185 cells expressing two or more immunomodulator genes rejected challenge 50-76% of the t
146 ferent medication regimens: (1) conventional immunomodulators (ie, oral prednisolone >10 mg/day, thio
147 h pre-established criteria for escalation to immunomodulators (ie, thiopurines) or anti-tumor necrosi
149 vel chemotherapies including epothilones and immunomodulators (IMiDs), as well as other novel agents
150 lymerase inhibitors in only 2 cases, and the immunomodulators imiquimod and thalidomide allowed 5 pat
151 i-GMP may be used clinically as an effective immunomodulator, immune enhancer, and vaccine adjuvant t
152 used clinically in humans and animals as an immunomodulator, immune enhancer, immunotherapeutic, imm
153 rial, CYT003, a Toll-like receptor-9 agonist immunomodulator, improved asthma control during inhaled
154 r necrosis factor (TNF)alpha with that of an immunomodulator in attaining clinical remission and faci
155 in, acting as an innate antibiotic and as an immunomodulator in diseases such as rosacea and psoriasi
156 t complement activation serves as a critical immunomodulator in lung cancer progression, acting to dr
158 yl)ethyl]-1,3-propanediol hydrochloride), an immunomodulator in Phase III trials for patients with mu
159 the potential therapeutic use of this novel immunomodulator in the treatment of metastatic diseases.
160 propose a novel role for a HABP as an innate immunomodulator in the treatment of MSSA and MRSA surgic
164 gh phosphocholine oligosaccharides are known immunomodulators in human nematode and trematode infecti
165 or dose reduction) of anti-TNF agents and/or immunomodulators in patients in remission from IBD.
166 d esters, have been used as highly effective immunomodulators in patients with multiple sclerosis and
167 go-related gene (ERG) potassium channels and immunomodulators in the control of rest and locomotor ac
168 ave been raised regarding the use of topical immunomodulators in young children with atopic dermatiti
169 imum tolerated dose of lenalidomide, an oral immunomodulator, in Japanese patients with relapsed adul
173 choosing to stop either the anti-TNF or the immunomodulator is a case-by-case decision based on the
175 onstrate that the oral administration of the immunomodulator JBT 3002 combined with i.p. injection of
176 ect of irinotecan (CPT-11) combined with the immunomodulator JBT 3002, a synthetic bacterial lipopept
177 at transcriptional regulation of a subset of immunomodulators, known as the staphylococcal superantig
180 include the proteasome inhibitor bortezomib, immunomodulator lenalidomide, and Bruton's tyrosine kina
181 mised their ability to induce NOD2-dependent immunomodulators like cyclooxygenase (COX)-2, suppressor
183 suggest that the use of costimulation-based immunomodulators may have significant repercussions on t
184 ests that high levels of vitamin D, a potent immunomodulator, may decrease the risk of multiple scler
185 ity Index (CCI), radiation and chemotherapy, immunomodulator medications, albumin, preoperative diagn
186 ctadecylammonium liposomes incorporating two immunomodulators (monomycolyl glycerol analog and polyin
187 antibiotics (RR, 0.41; 95% CrI, 0.15-0.92), immunomodulator monotherapy (RR, 0.33; 95% CrI, 0.13-0.6
188 antibiotics (RR, 0.26; 95% CrI, 0.08-0.61), immunomodulator monotherapy (RR, 0.36; 95% CrI, 0.17-0.6
190 lation [drug cessation or dose reduction] of immunomodulator monotherapy, 8 on immunomodulator de-esc
191 been used to promote the delivery of a model immunomodulator, mycophenolic acid (MPA), to the lymphat
192 erity (CDEIS) from the Study of Biologic and Immunomodulator Naive Patients in Crohn's Disease (SONIC
193 rom its role (i) as an immunogen, (ii) as an immunomodulator of host anti-inflammatory activities, or
195 ing the possibility to use sGARP as a potent immunomodulator of inflammatory diseases including trans
196 st report to show the potential of VIP as an immunomodulator of Pg-stimulated inflammatory pathways i
198 n be broadly applied to other small-molecule immunomodulators of interest for vaccines and immunother
201 n) with anti-CD3 antibody (a T cell-directed immunomodulator) offers better protection than either en
202 e examined the effects of PGE2, a well-known immunomodulator, on the production of IL-23 by bone marr
206 enable delivery of imaging contrast agents, immunomodulators, or chemotherapy agents in adoptive cel
207 our necrosis factor alpha (TNFalpha) agents, immunomodulators, or colectomy among those initially tre
209 ts, such as calcineurin inhibitors and other immunomodulators, or novel anti-inflammatory treatments,
210 interferon, pipobroman, anagrelide, approved immunomodulators, or observation without pharmacological
211 with fit patients (9% after TNF and 7% after immunomodulators; P < .01 for frail vs fit in both group
212 uct containing polyclonal antibodies, act as immunomodulator peripherally and centrally, and it can r
213 monoclonal antibodies, virulence disruptors, immunomodulators, phage therapies, microbiome-based ther
214 xamine the potency of two beta-chemokines as immunomodulators, plasmid DNA encoding beta-chemokines C
217 te dysregulation occurs through the negative immunomodulators programmed death-1 (PD-1) and suppresso
218 rgone a considerable and unique expansion of immunomodulator proteins, some of which we highlight as
219 pha, and downregulation of NF-kappa B by the immunomodulator pyrrolidinedithiocarbamate enhanced the
220 rotein or peptide antigens and a tolerogenic immunomodulator, rapamycin, to induce durable and antige
221 remained superior to early treatment with an immunomodulator (relative risk, 1.51; 95% CI, 1.20-1.89;
224 design could be adapted to drive additional immunomodulators, sense other cancers, and potentially t
225 ents in clinical remission who are receiving immunomodulators should be assessed for mucosal healing
226 , controversies have emerged as to how these immunomodulators should be used in clinical practice, ei
227 H. pylori or treated with H. pylori-derived immunomodulators showed reduced anaphylaxis upon allerge
228 vaccination against a secreted tick salivary immunomodulator, sialostatin L2, can lead to decreased f
233 ammatory cell death that can be leveraged by immunomodulators such as the danger signal calreticulin.
235 slation of several classes of small-molecule immunomodulators, such as imidazoquinoline TLR7/8 agonis
236 on of inflammatory cytokines and noncytokine immunomodulators, such as PGE2, during differentiation a
238 treatment of skin disease, using the topical immunomodulators tacrolimus, pimecrolimus, and imiquimod
239 t shutoff (vhs) protein is a multifunctional immunomodulator that counteracts the innate immune respo
242 TLR4 protein levels in mice treated with an immunomodulator that increases survival in polymicrobial
243 hmania-derived trimannose represents a novel immunomodulator that provides early type 1-skewed cytoki
244 sgammac expression is a naturally occurring immunomodulator that regulates gammac cytokine signaling
245 hosphate dehydrogenase inhibitors, and other immunomodulators that are being evaluated as adjunctive
248 such as the administration of antigens with immunomodulators that mobilize and activate endogenous D
249 trated that the anthrax toxins are important immunomodulators that promote immune evasion of the bact
251 resents a new class of vaccine adjuvants and immunomodulators that stimulate NKT cells to secrete Th1
255 -up therapy (acceleration to biologic and/or immunomodulator therapy only after failure of 5-aminosal
256 l [CI], 1.14-1.75; P = .0017), whereas early immunomodulator therapy was no different than no early i
257 95% CI, 1.20-1.89; P = .0004), whereas early immunomodulator therapy was no different than no early i
258 y associated with combination adalimumab and immunomodulator therapy with that of adalimumab monother
259 of top-down (upfront use of biologics and/or immunomodulator therapy) vs step-up therapy (acceleratio
263 ly, glycine has been shown to be a potential immunomodulator; therefore, the purpose of this study wa
265 al strategy is the use of chemotherapy as an immunomodulator to enhance the effect of cancer vaccines
266 during fungal infection, where it acts as an immunomodulator to promote fungal clearance and to regul
268 mia cells with lentiviral vectors to express immunomodulators to elicit antileukemic immune responses
269 cy and pluripotency evolved in tick salivary immunomodulators to evade immune recognition by the host
271 n secrete high levels of cytokines and other immunomodulators to mediate host defense and tissue infl
272 he basis of nanomaterials' ability to direct immunomodulators to tumours and lymphoid organs, to alte
274 pical and systemic corticosteroids, systemic immunomodulators, topical and systemic retinoids, and la
276 , while a mosquito bite alone induced strong immunomodulators (tumor necrosis factor alpha [TNF-alpha
277 witching therapy to fingolimod or injectable immunomodulators up to 12 months after on-treatment clin
278 associated with long-term corticosteroid and immunomodulator use if topical medication is not suffici
279 ncentrations showed an independent effect of immunomodulator use on week 54 non-remission (odds ratio
282 . pylori components (bacterial lysate or the immunomodulator VacA) and subsequently subjected them to
283 erinatal exposure to H pylori extract or its immunomodulator vacuolating cytotoxin confers robust pro
285 human immunodeficiency virus type 1 (HIV-1) immunomodulator VPU, reduced steady-state levels of bone
287 el host cell proteins downregulated by viral immunomodulators, we previously observed that K5, as wel
288 F therapy and 7% of patients who received an immunomodulator were frail in the 2 years before immunos
289 hage population induced by a single parasite immunomodulator, which protects against mucosal inflamma
290 oactive intestinal peptide (VIP) is a potent immunomodulator, whose role in PDC function is unknown.
291 diseases, establishing CD45 as an important immunomodulator with a significant influence on disease
293 monotherapy (RR, 0.36; 95% CrI, 0.17-0.63), immunomodulator with antibiotics (RR, 0.11; 95% CrI, 0.0
294 monotherapy (RR, 0.33; 95% CrI, 0.13-0.68), immunomodulator with antibiotics (RR, 0.16; 95% CrI, 0.0
296 unexpected features of SA-4-1BBL as a novel immunomodulator with implications for cancer immunopreve
297 how for the first time that AICAR is a novel immunomodulator with promising beneficial effects for th
299 Use of anti-TNF agents, corticosteroids, and immunomodulators within 90 days of surgery was identifie
300 VB radiation induces sunburn and is a potent immunomodulator, yet longer-wavelength, lower-energy UVA