ライフサイエンスコーパス: immunopathogenesis

1 related to coronavirus, including involving immunopathogenesis.

2 phagocytosis and also suppresses PcP-related immunopathogenesis.

3 a sequence and expression level modulate T1D immunopathogenesis.

4 nent of Pneumocystis pneumonia (PcP)-related immunopathogenesis.

5 ry response, which is the key feature of its immunopathogenesis.

6 lexity fits better with our understanding of immunopathogenesis.

7 Malaria is associated with complicated immunopathogenesis.

8 mune diseases might have opposite effects on immunopathogenesis.

9 l intervention and help in understanding NiV immunopathogenesis.

10 derstood as is the precise role of DCs in AC immunopathogenesis.

11 two independent processes essential for the immunopathogenesis.

12 tion of B cells in our overall picture of MS immunopathogenesis.

13 e important roles in Chlamydia infection and immunopathogenesis.

14 g functions shaping the normal course of EAE immunopathogenesis.

15 s effector responses and eventually leads to immunopathogenesis.

16 ocal regulatory roles for B cells during EAE immunopathogenesis.

17 upstream mediator of innate immunity, in WNV immunopathogenesis.

18 ggesting a role for these cytokines in HIV-1 immunopathogenesis.

19 isturbed gut microbiota contributes to their immunopathogenesis.

20 are supportive of a primary T-cell-mediated immunopathogenesis.

21 ve been hypothesized to participate in lupus immunopathogenesis.

22 l clearance while attenuating PcP-associated immunopathogenesis.

23 local inflammation, thereby contributing to immunopathogenesis.

24 that will facilitate further studies of HDV immunopathogenesis.

25 oth of which could be associated with C-IRIS immunopathogenesis.

26 considerations in the development of dengue immunopathogenesis.

27 SS and reveal a novel role for IL-17A in TSS immunopathogenesis.

28 njury and significantly contributes to early immunopathogenesis.

29 e proinflammatory responses that can lead to immunopathogenesis.

30 ytosis and may also mask antigens that drive immunopathogenesis.

31 lpha production that may be a factor in AIDS immunopathogenesis.

32 the loss of Clc-5 1) exhibits IL-6-mediated immunopathogenesis, 2) significantly exacerbated DSS-ind

33 dy kinetics, 2) correlates of protection, 3) immunopathogenesis, 4) antigenic diversity and cross-rea

34 earch implicated cellular immunity in dengue immunopathogenesis, a wealth of newer data demonstrated

35 Some anti-cytokine agents relevant to MG immunopathogenesis also seem promising.

36 Despite advances in understanding its immunopathogenesis, an effective treatment remains to be

37 f enhancing fungal clearance while dampening immunopathogenesis and allow the rescue of severe PcP.

38 ive PcP, MyD88 signaling contributes to both immunopathogenesis and control of fungal burden.

39 uman model to better understand tuberculosis immunopathogenesis and facilitate vaccine development is

40 plications for understanding type 1 diabetes immunopathogenesis and for designing antigen-based immun

41 m for the analysis of virus transmission and immunopathogenesis and for the generation of novel "bar-

42 portant information to facilitate studies of immunopathogenesis and HCV vaccine design and evaluation

43 e that sex is an important variable in tumor immunopathogenesis and immunotherapy responses through d

44 onary infection will deepen our knowledge of immunopathogenesis and is crucial for developing effecti

45 Studies of the immunopathogenesis and mechanisms of protective immunity

46 y play an important role in HIV-1-associated immunopathogenesis and NK cell dysfunction observed duri

47 w will describe current understanding of the immunopathogenesis and pathophysiology of anaphylaxis, f

48 s an altered host immune response, modifying immunopathogenesis and protecting from cerebral disease.

49 These data inform the study of tuberculosis immunopathogenesis and strategies for evaluation and dev

50 the P2X7 receptor has a role in periodontal immunopathogenesis and suggest that targeting of the P2X

51 rate the most severe consequences of malaria immunopathogenesis and the prospect of host survival.

52 and shed light on the role of pDCs in HIV-1 immunopathogenesis and therapy.

53 tant for understanding type 1 diabetes (T1D) immunopathogenesis and to design immune monitoring and i

54 etric neuropathy', possibly having different immunopathogenesis and treatment responses.

55 models that could prove useful for studying immunopathogenesis and vaccine development against hepat

56 d phenomenon with important implications for immunopathogenesis and vaccine development.

57 Our data suggest a role for Notch-1 in SLE immunopathogenesis, and for the first time, we present m

58 tudies of hepatitis C virus (HCV) infection, immunopathogenesis, and resulting liver diseases have be

59 Yet, many aspects of its immunopathogenesis are not well understood.

60 Aspects of H pylori immunopathogenesis are reviewed and perspectives on the

61 elucidating the mechanisms of protection and immunopathogenesis associated with dengue virus infectio

62 SpA is further reinforced by similarities in immunopathogenesis at both anatomical sites and by the c

63 Differences in immunopathogenesis between MCL and LCL may result from a

64 with our hypothesis that SigF may mediate TB immunopathogenesis by altering cell membrane properties,

65 effector cells, CXCL10 may contribute to the immunopathogenesis by recruiting inflammatory cells.

66 r, our data suggest that despite the risk of immunopathogenesis, CD8+ T cells use a perforin-dependen

67 current information about the epidemiology, immunopathogenesis, clinical presentations, diagnosis, a

68 ads to peripheral viral kinetics and mucosal immunopathogenesis comparable with those caused by patho

69 ed mouse model should be useful for studying immunopathogenesis, diagnostic markers, and therapy of h

70 can illuminate studies of HCV transmission, immunopathogenesis, drug resistance development, and vac

71 that regulatory T (Treg) cells prevent liver immunopathogenesis during HIV-1 infection in a humanized

72 ide new insight linking Treg cells and liver immunopathogenesis during HIV-1 infection.

73 es which mediate protective immunity or host immunopathogenesis during M. tuberculosis infection in t

74 urn affects the adaptive immune response and immunopathogenesis during murine NCC.

75 neonatal RSV infection decreased Th2-biased immunopathogenesis during reinfection.

76 neonatal RSV infection decreased Th2-biased immunopathogenesis during reinfection.

77 including contributions to colonization and immunopathogenesis during vulvovaginal candidiasis.

78 r results demonstrate that the extent of the immunopathogenesis established early in HIV infection pr

79 r M1 and M2 alike) to a resting state, cease immunopathogenesis even as bacteria are eliminated by ot

80 ), potentially suggesting different roles in immunopathogenesis for complexes arising at different st

81 As insight in fungal immunopathogenesis forges ahead, interventions for boost

82 Infection-induced immunopathogenesis has been separately studied in humani

83 lexity of human immunodeficiency virus (HIV) immunopathogenesis has prompted multiple strategic appro

84 f experimental data on dry eye disease (DED) immunopathogenesis have been derived from a murine model

85 isms that contribute to dengue infection and immunopathogenesis have hampered the development of vacc

86 s is still unknown, recent insights into its immunopathogenesis have moved investigators closer to fi

87 trials, more sophisticated understanding of immunopathogenesis, histology, and specific autoantibody

88 and for the analysis of mechanisms of viral immunopathogenesis in AIDS.

89 oyed the db/db mouse model to understand WNV immunopathogenesis in diabetics.

90 eneity at the HLA region suggests a distinct immunopathogenesis in DR2 negative patients.

91 e the exploratory strategies used to dissect immunopathogenesis in human tuberculosis with the aim to

92 immune activation, and CD4(+) T cell death, immunopathogenesis in LTs during early infection remains

93 However, the immune response also drives immunopathogenesis in patients who develop severe PcP, a

94 tance, we examined whether a SIV that causes immunopathogenesis in pigtail macaques could be made sen

95 Immunopathogenesis in systemic viral infections can indu

96 The description of determinants of immunopathogenesis in TB is of tremendous interest due t

97 ter insight into the molecular correlates of immunopathogenesis in this disease model.

98 atory cells (Tregs) overlap or influence EAE immunopathogenesis independently has remained unanswered

99 In healthy individuals such immunopathogenesis is avoided by the presence of regulat

100 However, their role in immunopathogenesis is controversial.

101 resenting features, organ complications, and immunopathogenesis is important for timely diagnosis and

102 inflammasome complexes, but its role in WNV immunopathogenesis is not defined.

103 frequently fatal opportunistic mycosis whose immunopathogenesis is poorly understood.

104 The immunopathogenesis is still poorly known, but it has bee

105 luding hepatitis C virus (HCV) infection and immunopathogenesis, is essential for the study of hepati

106 may indicate a contribution of grancalcin to immunopathogenesis, it is not essential for vital leukoc

107 The resulting immunopathogenesis leads to lesions in epithelial lining

108 studies focusing on better understanding of immunopathogenesis may facilitate vaccine development an

109 uggests that slightly distinct mechanisms of immunopathogenesis may operate in susceptible C57BL/6 an

110 f celiac disease and how current concepts of immunopathogenesis might provide alternative approaches

111 The evolving epidemiology, immunopathogenesis, molecular virulence studies, early d

112 rhesus macaque model closely resembles HIV-1 immunopathogenesis, neuropathogenesis, and disease progr

113 self-antigens may play a central role in the immunopathogenesis of AAA.

114 ce DCs via CCR7 expression contribute to the immunopathogenesis of AC, thereby allowing significant i

115 static IL-10 responses may contribute to the immunopathogenesis of active tuberculosis and propagatio

116 ults demonstrate for the first time that the immunopathogenesis of adhesion formation is under the co

117 effector mechanism(s) that fails during the immunopathogenesis of AIDS to allow onset and progressio

118 In the present study, pathways in the immunopathogenesis of ALI were evaluated.

119 al and cellular responses and focused on the immunopathogenesis of allergic diarrhea.

120 litates studies on the role of lipids in the immunopathogenesis of allergy.

121 odel is a major advance in understanding the immunopathogenesis of AMR.

122 ss has been made in our understanding of the immunopathogenesis of ANCA-associated vasculitides.

123 forward and broaden the traditional focus of immunopathogenesis of arterial disease, with the goal of

124 repair, host defense and is involved in the immunopathogenesis of asthma.

125 er, we describe the role of vitamin D in the immunopathogenesis of atopic dermatitis and other allerg

126 nd fibroproliferation, the central events in immunopathogenesis of BOS following human lung transplan

127 ead toward new insights into the fundamental immunopathogenesis of brucellosis.

128 se as important virulence components for the immunopathogenesis of Candida vaginitis, with implicatio

129 The immunopathogenesis of cardiomyopathy, the main clinical

130 ttle is known about their partnership in the immunopathogenesis of Chagas disease, the chronic infect

131 The immunopathogenesis of Chlamydia trachomatis-induced ovid

132 results have important implications for the immunopathogenesis of chlamydial disease and new vaccine

133 rahepatic lymphocytes is associated with the immunopathogenesis of chronic hepatitis C disease.

134 gest that they play an important role in the immunopathogenesis of chronic hepatitis C.

135 are believed to be directly involved in the immunopathogenesis of chronic liver diseases.

136 en hypothesized to play an important role in immunopathogenesis of chronic rejection of transplanted

137 sponses to self-antigens that contributes to immunopathogenesis of chronic rejection.

138 ng complement, an important component in the immunopathogenesis of CIA.

139 The immunopathogenesis of CM immune reconstitution inflammat

140 role for chemokines in immune evasion and/or immunopathogenesis of CMV retinitis.

141 trophil recruitment, and contributing to the immunopathogenesis of crescentic GN.

142 of effector responses may play a role in the immunopathogenesis of DEN hemorrhagic fever.

143 lymphocytes is thought to contribute to the immunopathogenesis of dengue disease during secondary in

144 cific antibodies have been implicated in the immunopathogenesis of dengue during infancy.

145 IL-18 are two cytokines associated with the immunopathogenesis of diabetes in NOD mice.

146 should lead to a better understanding of the immunopathogenesis of disease and to more specifically t

147 s) are known to play a prominent role in the immunopathogenesis of disease.

148 TLR) 4 and determine its contribution to the immunopathogenesis of dry eye disease (DED).

149 ributes to the predominantly T-cell-mediated immunopathogenesis of dry eye disease.

150 Advances in understanding the immunopathogenesis of each of these entities offer many

151 s GP which may play an important role in the immunopathogenesis of Ebola virus infection.

152 pheral nerve damage in leprosy patients, the immunopathogenesis of ENL remains ill-defined.

153 h exacerbation severity, but its role in the immunopathogenesis of exacerbations has remained elusive

154 les encoded by these genes contribute to the immunopathogenesis of experimental autoimmune encephalom

155 termine if autoantibodies play a role in the immunopathogenesis of experimental dry eye disease.

156 patterns of sequence change might reveal the immunopathogenesis of fibrosis progression.

157 n the host-parasite relationship, especially immunopathogenesis of filarial infection, may improve ou

158 used single-cell RNA sequencing to study the immunopathogenesis of GA and also evaluated the efficacy

159 from basic research primarily related to the immunopathogenesis of H pylori that have advanced the pr

160 ings may have important implications for the immunopathogenesis of HCV in both immune and hepatic cel

161 age underpinning the role of NK cells in the immunopathogenesis of HCV.

162 ection and dysfunction may contribute to the immunopathogenesis of HIV disease.

163 evels of CD8+ T cells may play a role in the immunopathogenesis of HIV in the female genital tract.

164 role of opioids, including methadone, in the immunopathogenesis of HIV infection and AIDS.

165 ay have significant in vivo relevance to the immunopathogenesis of HIV infection and AIDS.

166 that meth may function as a cofactor in the immunopathogenesis of HIV infection and may lead to the

167 irm that the GI tract is a key player in the immunopathogenesis of HIV infection, and they reveal a s

168 ggest a potential unique role of pDCs in the immunopathogenesis of HIV-1 infection by inducing the de

169 tes the early viral replication dynamics and immunopathogenesis of HIV-1 infection of humans and thus

170 Ls) have important and opposing roles in the immunopathogenesis of HIV-1 infection.

171 inflammation in lymphoid tissues and in the immunopathogenesis of HIV-1/SIV, and suggest that TLR3 l

172 CD4+ T cells play a central role in the immunopathogenesis of HIV/AIDS, and their depletion duri

173 hinders a more complete understanding of the immunopathogenesis of HTLV-1 infections.

174 generated significant new insights into the immunopathogenesis of human celiac disease.

175 function of LY6E and sheds new light on the immunopathogenesis of human coronavirus infection.

176 can exacerbate bacterial infections and the immunopathogenesis of human immunodeficiency virus type

177 s on current approaches to understanding the immunopathogenesis of human T cell lymphotropic virus (H

178 ity of powerful new tools for dissecting the immunopathogenesis of human tuberculosis, the generation

179 okines which are known to be involved in the immunopathogenesis of IBD.

180 The immunopathogenesis of immune reconstitution inflammatory

181 tumor-infiltrating lymphocytes (TILs) in the immunopathogenesis of individual cancer is a challenge f

182 phocytes (CTLs) play a prominent role in the immunopathogenesis of infection by the noncytolytic, per

183 L specificity may have a pivotal role in the immunopathogenesis of infection, and that simple quantit

184 eukocytes is known to strongly influence the immunopathogenesis of infection.

185 To investigate the immunopathogenesis of inflammation-associated fibrosis,

186 n, but little is known about its role in the immunopathogenesis of inflammatory bowel disease (IBD).

187 ng other cytokines likely have a role in the immunopathogenesis of IRIS.

188 learly identified as a Th1 inflammation, the immunopathogenesis of its counterpart inflammatory bowel

189 d LTB4 mediator pathways are involved in the immunopathogenesis of LPS-induced experimental ALI.

190 ify a complex role for MMPs and TIMPs in the immunopathogenesis of lung allograft rejection, and indi

191 The complement pathway was implicated in the immunopathogenesis of lupus and other autoimmune disorde

192 (MIF) place it in a central position in the immunopathogenesis of many diseases.

193 microglia/macrophages play a key role in the immunopathogenesis of MS and its corresponding animal mo

194 The immunopathogenesis of multiple sclerosis (MS) has always

195 o the CNS is a prominent feature driving the immunopathogenesis of multiple sclerosis and its animal

196 An evolving understanding of the immunopathogenesis of multiple sclerosis suggests that d

197 plicate antibody-dependent mechanisms in the immunopathogenesis of multiple sclerosis.

198 thogen interactions and participating in the immunopathogenesis of mycobacterial infections.

199 implicate IL-6 as a critical molecule in the immunopathogenesis of NMO, and a critical role for T cel

200 ion of immune responses to self-antigens and immunopathogenesis of OAD following the administration o

201 tivation and alloantibody development in the immunopathogenesis of OAD.

202 M has emerged as an important host factor in immunopathogenesis of ocular HSV type 1 (HSV-1) infectio

203 suggests a potential role for PG(Bb) in the immunopathogenesis of other Lyme disease manifestations.

204 The immunopathogenesis of paradoxical tuberculosis-associate

205 D8(+) T cells play a significant role in the immunopathogenesis of PBC.

206 te that mast cells and TNF contribute to the immunopathogenesis of periodontitis and may offer therap

207 Similarities exist in the epidemiology and immunopathogenesis of periodontitis and rheumatoid arthr

208 s jiroveci (P. jiroveci) is important in the immunopathogenesis of Pneumocystis pneumonia (PcP), but

209 Advances in understanding the immunopathogenesis of PsA have helped to facilitate the

210 p to further refine our understanding of the immunopathogenesis of PsA.

211 ed therapies inform our understanding of the immunopathogenesis of PsA.

212 Recognition of the immunopathogenesis of psoriatic arthritis, as with rheum

213 approaches to define factors underlying the immunopathogenesis of pulmonary diseases including sarco

214 e notion of a potential role of IP-10 in the immunopathogenesis of RA.

215 prevalent African allele HLA-B*53:01 in the immunopathogenesis of raltegravir-induced DRESS syndrome

216 N and the contribution of these cells in the immunopathogenesis of ReA, which may provide evidence fo

217 immune pathways that might contribute to the immunopathogenesis of recalcitrant synovitis in PIRRA, a

218 o play an important role in the immunity and immunopathogenesis of respiratory syncytial virus (RSV)

219 The immunopathogenesis of rheumatoid arthritis (RA) spans de

220 emokine that potentially plays a role in the immunopathogenesis of rheumatoid arthritis (RA).

221 ibute to disease susceptibility, whereas the immunopathogenesis of RPF is mediated by different immun

222 is model provides a means to investigate the immunopathogenesis of RSV infection and its association

223 Although T cells have been implicated in the immunopathogenesis of secondary infections with heterolo

224 The immunopathogenesis of severe dengue is poorly understood

225 ole for cross-reactive memory T cells in the immunopathogenesis of severe disease.

226 ce will provide additional insights into the immunopathogenesis of severe EBOV disease.

227 polymorphic variability in conditioning the immunopathogenesis of severe malarial anemia (SMA) remai

228 ral models have been proposed to explain the immunopathogenesis of severe T cell-mediated drug HSRs,

229 aberrant cytokine secretion that drives the immunopathogenesis of Sezary syndrome and other immunopa

230 The observations strengthen the immunopathogenesis of sIBM, and offer the basis for futu

231 arallels the increasing understanding of the immunopathogenesis of SLE and looks promising.

232 strate an extended role for CREMalpha in the immunopathogenesis of SLE because it contributes to incr

233 amage that are the essential features of the immunopathogenesis of SLE.

234 al functions, exerts a dual influence on the immunopathogenesis of SLE.

235 ays and provide mechanistic insight into the immunopathogenesis of SLE.

236 Although the immunopathogenesis of SMA is largely undefined, we have

237 ctors VEGF and GM-CSF may be involved in the immunopathogenesis of subjects with CRS and nasal polyps

238 body-mediated neuronal cell signaling in the immunopathogenesis of Sydenham chorea and will lead to a

239 Much less is known about the immunopathogenesis of syndromes that affect the central

240 A peptide binding groove is important in the immunopathogenesis of T-cell mediated drug hypersensitiv

241 am-negative pathogens to host cells, but the immunopathogenesis of TAAs remains unknown.

242 n update of the current understanding of the immunopathogenesis of TED and explore these mechanisms f

243 ressive advances in the understanding of the immunopathogenesis of TED continue to spur clinical tria

244 (+) CTLs, thought to be major players in the immunopathogenesis of the disease.

245 the understanding of the immunogenetics and immunopathogenesis of the IIMs may in the future provide

246 re, we utilize rhesus macaques to define the immunopathogenesis of the recently developed SHIV.CH505,

247 a2(+) T-cell responses may contribute to the immunopathogenesis of the SIV-related tuberculosis-like

248 hough there are important differences in the immunopathogenesis of these 2 viral pathogens, little is

249 In just over 20 years, many aspects of the immunopathogenesis of these diseases have been dissected

250 gaps in knowledge remain with regard to the immunopathogenesis of these diseases.

251 AR, suggesting potential differences in the immunopathogenesis of these diseases.

252 rides in our understanding of the underlying immunopathogenesis of these disorders, which have led to

253 nsight into the mechanisms that underlie the immunopathogenesis of these persistent viral infections

254 or a model system to investigate the complex immunopathogenesis of this chronic disease and subsequen

255 Further understanding of the immunopathogenesis of this condition will facilitate dev

256 on caused by Mycobacterium tuberculosis, the immunopathogenesis of this disease is poorly understood.

257 tes and their functional relationship in the immunopathogenesis of this disease model by using mice d

258 on could provide important insights into the immunopathogenesis of this disease.

259 To define the immunopathogenesis of this malaria-induced pregnancy com

260 ells and enterocytes) may play a role in the immunopathogenesis of this pathogen-driven experimental

261 To characterize the immunopathogenesis of this syndrome, we studied viral lo

262 However, the immunopathogenesis of TSS and other diseases involving S

263 The immunopathogenesis of tuberculosis-associated immune rec

264 is surface are important determinants in the immunopathogenesis of tuberculosis.

265 d migrating capacities and their role in the immunopathogenesis of tuberculosis.

266 ould have implications for their role in the immunopathogenesis of tuberculosis.

267 The immunopathogenesis of type 1 diabetes mellitus is associ

268 The immunopathogenesis of type 1 diabetes mellitus is associ

269 disease-relevant CD8 T cells that inform the immunopathogenesis of type 1 diabetes.

270 regulation, implying a role for CLC-5 in the immunopathogenesis of UC.

271 e TNF is thought to play a major role in the immunopathogenesis of ulcerative colitis, and anti-TNF a

272 response is important for understanding the immunopathogenesis of VL.

273 /IL-17 axis signaling is dispensable for the immunopathogenesis of VVC.

274 The molecular immunopathogenesis of West Nile virus (WNV) infection is

275 geneic bone marrow transplantation (BMT) the immunopathogenesis of which is not well understood.

276 provides unique mechanistic insight into the immunopathogenesis of WNVE observed in diabetics and can

277 Little is known about the immunopathogenesis of ZIKV-associated microcephaly.

278 etal system might have similar mechanisms of immunopathogenesis owing to conserved responses to mecha

279 st exclusively been held responsible for its immunopathogenesis, partly because certain MHC class II

280 CD8(+) T suppressor cell recruitment, limits immunopathogenesis, preserves lung function, and enhance

281 stain the autoreactive T cells essential for immunopathogenesis, promoting their accumulation and dis

282 ndscape will improve the understanding of TB immunopathogenesis, providing potential targets for ther

283 and highlight a significant aspect of viral immunopathogenesis related to the progression of adult T

284 rucellosis diagnostics and understanding the immunopathogenesis related to this intracellular pathoge

285 syndrome; however, the complexities of DENV immunopathogenesis remain controversial.

286 While the parameters contributing to dengue immunopathogenesis remain unclear, the collapse of redox

287 g monocyte apoptosis response may inform HIV immunopathogenesis, retention of infected macrophages, a

288 Immunopathogenesis studies employing West Nile virus (WN

289 tests for liver disease staging; additional immunopathogenesis studies in children with HBV infectio

290 of viral replicative capacity (vRC) on HIV-1 immunopathogenesis that is independent of viral load (VL

291 llenges, epidemiology, aetiology, pathology, immunopathogenesis, therapy, genetic influences, and the

292 w regulatory mechanisms to be overridden and immunopathogenesis to proceed.

293 Respiratory syncytial virus (RSV) immunopathogenesis was evaluated in 129xC57BL/6, C57BL/6

294 AC immunopathogenesis was evaluated via clinical examinatio

295 ole of mycobacterial antigens in sarcoidosis immunopathogenesis, we assessed the immune recognition o

296 evaluate the importance of this mechanism of immunopathogenesis, we determined the relative contribut

297 role of each immune component in human tumor immunopathogenesis, we have studied the interaction betw

298 We propose that sex differences in immunopathogenesis will inform mechanisms of COVID-19, i

299 ds to identify genetic factors, studying the immunopathogenesis with human tissue and animal models,

300 e of MyD88 in the development of PcP-related immunopathogenesis, WT and MyD88(-/-) mice were rendered