ライフサイエンスコーパス: immunopathologic

1 lar endomyocardial biopsies is diagnostic of immunopathologic AMR but serves more as a late-stage mar

2 In cardiac allograft biopsies with immunopathologic AMR, IR spectroscopy reveals a biochemi

3 The immunopathologic and clinical similarities between chron

4 D/LtSz-Rag1nullPfpnull mice were studied for immunopathologic and hematologic abnormalities.

5 In the first posttransplantation year, AMR immunopathologic and histopathologic markers were relati

6 wanted to investigate the reproducibility of immunopathologic and physiologic parameters after short

7 Both diseases appear to be immunopathologic, and inflammatory mediators are importa

8 and case series study included demographic, immunopathologic, and serologic data from 300 patients d

9 This may also be the immunopathologic basis of other life-threatening human v

10 The lesion is immunopathologic, but the identities of molecules that d

11 AMR) is diagnosed and graded on the basis of immunopathologic (C4d-CD68) and histopathologic criteria

12 inia virus keratitis is likely to involve an immunopathologic component, but little is known about th

13 use models has resulted in resolution of the immunopathologic condition.

14 nd DC-expressed nuclear receptors to various immunopathologic conditions, such as rheumatoid arthriti

15 The requirement for immunopathologic confirmation of MMP by autoantibody det

16 Stromal keratitis is an immunopathologic consequence of herpes simplex virus (HS

17 mechanisms for signal controls and important immunopathologic consequences including resistance to cy

18 immunoprotective responses without inducing immunopathologic consequences.

19 atial distribution within the tissue and the immunopathologic cues contributing to disease progressio

20 changes, thus extending the consideration of immunopathologic cytokines in Down syndrome beyond inter

21 enous IL-10 can be effective in ameliorating immunopathologic damage associated with schistosomiasis.

22 these chronic viruses at bay while avoiding immunopathologic damage to persistently infected tissues

23 Immunopathologic damage was moderate to widespread in up

24 ar and cytokine/chemokine responses to limit immunopathologic damage, while maintaining host control

25 n immunosuppressive factor produced to limit immunopathologic damage.

26 s adds important information to clinical and immunopathologic data in discriminating between primary

27 ed immunosorbent assay (ELISA); clinical and immunopathologic data were obtained from the patients' m

28 nd SP-D-deficient mice exhibited evidence of immunopathologic defects, the CD11b(high) CD11c(high) de

29 imilar regulatory network may be controlling immunopathologic disease in man.

30 Herpes stromal keratitis is an immunopathologic disease in the corneal stroma leading t

31 ith herpes simplex virus (HSV) results in an immunopathologic disease of the eye termed herpetic stro

32 including fungi, predisposes individuals to immunopathologic disease upon subsequent encounters with

33 This immunopathologic disease, called herpetic stromal kerati

34 ntribute to protection from infection and to immunopathologic disease.

35 rpes simplex virus keratitis, a well-studied immunopathologic disease.

36 the environment of the eye, culminates in an immunopathologic disease.

37 Genes controlling immunopathologic diseases of differing etiopathology may

38 a novel immune modulator in a broad array of immunopathologic disorders.

39 the mechanisms by which T cells exert their immunopathologic effects in experimental autoimmune kera

40 rpesvirus spread with associated undesirable immunopathologic effects.

41 7 days after irradiation and histopathologic-immunopathologic evaluation after excision on the sevent

42 sis is characterized by a complex cascade of immunopathologic events, including leukocyte recruitment

43 oid serum autoantibody tests did not provide immunopathologic evidence of MMP in ocular-only MMP pati

44 Immunopathologic examination of biopsies revealed strong

45 , thus directly addressing the telomere loss immunopathologic facet of chronic viral infection.

46 ters with the same clinical, histologic, and immunopathologic features as those documented in BALB/c

47 The immunopathologic features of BP can be reproduced in mic

48 This series describes the immunopathologic features of posterior embryotoxon (PE)

49 view, we describe the genetic, clinical, and immunopathologic features of these 2 disorders and discu

50 ental animals with clinical, histologic, and immunopathologic features similar to those seen in human

51 e rat, another species that shares essential immunopathologic features with human uveitis and is the

52 lies on characteristic clinicopathologic and immunopathologic features.

53 Some of the described immunopathologic findings (activation, proliferation, ap

54 nonbullous pemphigoid for all patients with immunopathologic findings of bullous pemphigoid, itch, a

55 teen patients with itch without blisters had immunopathologic findings of bullous pemphigoid.

56 atively consistent clinical, histologic, and immunopathologic findings.

57 ons with the potential for both antiviral or immunopathologic functions.

58 In conclusion, IL-15 prevents two immunopathologic hallmarks of sepsis, namely, apoptosis

59 This association may be due to an immunopathologic HLA-A*6802-restricted cytotoxic T lymph

60 c, proinflammatory state and a multicellular immunopathologic host death that is predominantly driven

61 l IFN-gamma(+) ILC1 and increased numbers of immunopathologic IL-5(+) and IL-13(+) ILC2 and IL-17A(+)

62 ciple, it may be possible to ameliorate this immunopathologic indirect mechanism by developing therap

63 renchyma is believed to protect the CNS from immunopathologic injury.

64 This represents a CD4+ T cell-mediated immunopathologic lesion in both humans and a mouse model

65 keratitis (HSK) is a CD4+ T cell-controlled immunopathologic lesion in the eye that results from inf

66 SV-1 infection, represents a T cell-mediated immunopathologic lesion.

67 We confirmed that AD is heterogeneous at the immunopathologic level and identified 4 distinct biomark

68 roup, with a greater frequency of additional immunopathologic manifestations and a greater median num

69 The immune response and immunopathologic manifestations in schistosomiasis are l

70 AMR2 grade (simultaneous histopathologic and immunopathologic markers) was predictive for clinical AM

71 GC in enlarged lung LNs represents a shared immunopathologic mechanism associated with progressive p

72 the syndrome suggest that it is mediated by immunopathologic mechanism.

73 ificant potential for the long-term study of immunopathologic mechanisms and novel therapies in rheum

74 Our data highlight novel immunopathologic mechanisms and validate ongoing and fut

75 This review will discuss the immunopathologic mechanisms involved in these demyelinat

76 infection of normal mice results in a fatal immunopathologic meningitis mediated by CD8+ cytotoxic T

77 ost tracheal mucosae infected with virulent, immunopathologic Mycoplasma gallisepticum; however, mech

78 sitions into hyphae resulting in an aberrant immunopathologic neutrophil response that contributes to

79 riable immunodeficiency display clinical and immunopathologic overlap with sarcoidosis.

80 n of endotypes driven by distinct underlying immunopathologic pathways might be useful to define pedi

81 therefore, a need to better understand local immunopathologic pathways.

82 e examined sera from patients with different immunopathologic patterns of MS as determined by brain b

83 ns are increasingly becoming associated with immunopathologic phenomena, being induced in response to

84 nt of the immune-mediated, virus-independent immunopathologic process as a primary mechanism in sever

85 ese studies provide strong evidence that the immunopathologic process characteristic of the two major

86 coronavirus 2 (SARS-CoV-2) or an independent immunopathologic process is unknown.Objectives: To deter

87 cules to regulate this chronic virus-induced immunopathologic process.

88 To evaluate the underlying immunopathologic processes that cause graft rejection, w

89 n correlated inversely with the airway T(H)2 immunopathologic profile (eosinophilia and IL-4 positivi

90 e to failure of CD4+ T cells to organize the immunopathologic reaction.

91 y of infectious and atopic diseases in which immunopathologic reactions are mediated by selected Th2

92 ere is also the potential to develop adverse immunopathologic reactions characterized by pulmonary ai

93 a critical regulatory role in development of immunopathologic reactions in Mycoplasma respiratory dis

94 f Th2 cells, which may contribute to serious immunopathologic reactions in the lung.

95 onses in IFN-gamma(-/-) mice corresponded to immunopathologic reactions that developed after mycoplas

96 mine the immunologic responses, particularly immunopathologic reactions, associated with nasal immuni

97 Ad37 induces an acute immunopathologic response in the C57BL/6J mouse cornea,

98 x virus-1 in immunocompetent mice induces an immunopathologic response termed herpetic stromal kerati

99 istinguishing mechanisms associated with the immunopathologic response to the virus from those associ

100 A trend toward reduced immunopathologic response was found in C-EX mice.

101 n anti-bacterial activity and control of the immunopathologic response.

102 ed tear breakup, ocular surface disease, and immunopathologic response.

103 CD4 T-cell-dependent, Th2-cytokine-dominated immunopathologic response.

104 We investigated physiologic, virologic, and immunopathologic responses to experimental RV infection

105 significant heterogeneity in therapeutic and immunopathologic responses to immune checkpoint therapie

106 ay lead to a failure to control induction of immunopathologic responses, and limitation in repertoire

107 xtent of immunologic responses, particularly immunopathologic responses, within the upper and lower r

108 To ascertain an immunopathologic role during disease, immunofluorescence

109 1 has been associated with PR3-ANCA, but its immunopathologic role was unclear.

110 eath-1 (PD-1), has been involved in multiple immunopathologic scenarios.

111 H. influenzae mimic epitope only induces an immunopathologic self-reactive Th1 response and subseque

112 Despite minimal immunopathologic sequelae in PD-1 and LAG-3 single knock

113 al immunostimulants that produce a number of immunopathologic sequelae, including lymphoproliferation

114 al model of antibody-mediated diseases as an immunopathologic spectrum whose specific manifestations

115 ge-scale prospective immunoepidemiologic and immunopathologic studies are needed to address gaps in o

116 Immunopathologic studies suggest that loss of aquaporin-

117 ponent of mycoplasma respiratory diseases is immunopathologic, suggesting that lymphocyte activation

118 unctivitis until more sensitive and specific immunopathologic tests become available.

119 as by shifting the residual response from an immunopathologic Th1 to a protective Th2 format.

120 D8+ cells, under the control of IL-4, dampen immunopathologic type 2 responses.

121 No adverse effects, clinical or immunopathologic, were noted.