ライフサイエンスコーパス: immunoreceptor

1 eracts with both the effector and the NB-LRR immunoreceptor.

2 ase involved in cell signaling downstream of immunoreceptors.

3 nct from those in other immunoglobulin-based immunoreceptors.

4 he molecular organization of many activating immunoreceptors.

5 mits signals upon ligation of many different immunoreceptors.

6 ed by cytokines dependent on TLR and/or MDA5 immunoreceptors.

7 standing of the mechanosensing properties of immunoreceptors.

8 to these aspartic acids, with the activating immunoreceptors.

9 alpha (SIRPalpha) is a membrane glycoprotein immunoreceptor abundant in cells of monocyte lineage.

10 uch as antisense oligonucleotides, aptamers, immunoreceptor-activating nucleotides, or (anti)microRNA

11 ory role for Btk and Tec that is mediated by immunoreceptor activation and signaling via PI3K.

12 ally encoded Ca(2+) signaling in response to immunoreceptor activation that utilizes TRPC channels to

13 evidence of a ceiling above which increased immunoreceptor affinity may adversely affect T cell resp

14 mmobility is a feature of highly crosslinked immunoreceptor aggregates and a trigger for receptor int

15 (SLP-76) is an adaptor molecule critical for immunoreceptor and integrin signaling in multiple hemopo

16 uggesting functional similarity between this immunoreceptor and tumor growth factor receptors.

17 plex class I (MHCI) family, and MHCI-binding immunoreceptors and their components (e.g., PIRB, Ly49,

18 d for their activities downstream of several immunoreceptors and then functionally mapped based on th

19 ing lymphocyte activating molecule family of immunoreceptors, and has an unknown function in CLL cell

20 state organisation and diffusion dynamics of immunoreceptors, and how this might impact on our unders

21 embrane is critical in the signaling of many immunoreceptors, and this mechanism has previously been

22 Like LAIR-1, CD33 inhibitory immunoreceptors are highly expressed on monocytes.

23 g the two clones with identical TCR Vbeta by immunoreceptor array showed higher phosphorylation of NK

24 conformational change and the triggering of immunoreceptors, as well as the effects of force on the

25 Many activating immunoreceptors associate with signaling adaptor molecul

26 The immunoreceptor-associated protein CD3zeta is known for i

27 d recruitment of this adaptor protein to the immunoreceptor-based activation motif (ITAM)-like sequen

28 s to pDCs via the C-type lectins DEC-205, DC immunoreceptor, blood DC Ag-2, or the FcR CD32 led to up

29 us vulgaris (PV), autoantigen-based chimeric immunoreceptors can direct T cells to kill autoreactive

30 ts demonstrate that phenomena that change an immunoreceptor chain's entropy (stiffening, confinement

31 in E2 is a novel ligand of pDC C-type lectin immunoreceptors (CLRs), blood DC antigen 2 (BDCA-2) and

32 L in human CAECs and indicate that these two immunoreceptors contribute to the mechanisms underlying

33 Upon activation by immunoreceptors, CPR5 undergoes an oligomer to monomer c

34 Dendritic cell immunoreceptor (DCIR) constructs in CHO cells or on DCs

35 estigated the role of the CLR dendritic cell immunoreceptor (DCIR) in the genesis of CM.

36 proteins, and given that the dendritic cell immunoreceptor (DCIR) is known to act as a negative regu

37 yrosine-based inhibitory motif-containing DC immunoreceptor (DCIR) to mediate potent cross-presentati

38 eport that C-type lectin dendritic cell (DC) immunoreceptor (DCIR), a key component in DC homeostasis

39 s (CLRs), blood DC antigen 2 (BDCA-2) and DC-immunoreceptor (DCIR).

40 By binding to these adhesion molecules, the immunoreceptors DNAX accessory molecule-1 (DNAM-1), CD96

41 Critical cell surface immunoreceptors downregulated during HIV infection have

42 These data support the notion that immunoreceptor downregulation occurs by a sequential pro

43 d calcium entry (SOCE), occurs downstream of immunoreceptor engagement and is critical for cytotoxic

44 able interest in the signaling mechanisms of immunoreceptors, especially when triggered with membrane

45 r expressed on myeloid cells-1) is an orphan immunoreceptor expressed on monocytes, macrophages, and

46 TREM2 is an immunoreceptor expressed on osteoclasts (OC) and microgl

47 esults suggest that tumor co-option of NKG2D immunoreceptor expression may complement the presence of

48 with homologous lectin-like domains from the immunoreceptor family reveals a similar but not identica

49 Activation of the plant immunoreceptor Flagellin sensing2 (FLS2) by its bacteria

50 re NLRs that appear to function as cytosolic immunoreceptors for specific bacterial proteins, includi

51 le nucleotide polymorphism (rs231725) of the immunoreceptor gene cytotoxic T-lymphocyte antigen 4 (CT

52 id D-MG spheroids exhibited higher levels of immunoreceptor genes in activating members, but the MG g

53 Many immunoreceptors have cytoplasmic domains that are intrin

54 ur data suggest that after the engagement of immunoreceptors, immune cells likely employ multiple mem

55 Siglec-7 is considered to function as an immunoreceptor in a sialic acid-dependent manner.

56 hosphorylated signaling motifs on regulatory immunoreceptors including PD-1, but its functional role

57 ase Syk is required for signaling of several immunoreceptors, including the BCR and FcR.

58 oprotein of 76 kDa) organizes signaling from immunoreceptors, including the platelet collagen recepto

59 We validate the system for a range of immunoreceptors, including the T-cell receptor (TCR), an

60 Signaling by immunoreceptors is often initiated by phosphorylation of

61 B7-H6, a member of the B7 family of immunoreceptors, is as a cell-surface ligand for the NKp

62 n motifs in the cytoplasmic tail of multiple immunoreceptors, leading to the initiation of cellular e

63 in-like-5/CD155) in complex with its cognate immunoreceptor ligand T-cell-Ig-and-ITIM-domain (TIGIT).

64 the presence of mechanical force on several immunoreceptor-ligand pairs and the important role of fo

65 d for producing multiple functionally active immunoreceptors, ligands, and viral decoys, including ch

66 In neutrophils, selectins also trigger an immunoreceptor-like signaling cascade that converts inte

67 ing with parallel signals from other surface immunoreceptors, making them multimolecular sensors of c

68 We discuss the types of forces that immunoreceptors may encounter and the effects of force o

69 promote phosphorylation events necessary for immunoreceptor-mediated inhibition of TLR signaling.

70 ther showed that, in contrast to its role in immunoreceptor-mediated signaling, LAB function in LPS-m

71 nsmembrane adaptor protein that functions in immunoreceptor-mediated signaling.

72 Movement of immunoreceptor microclusters tunes lymphocyte activation

73 These include adhesive receptors, immunoreceptors, motor proteins, cytoskeletal proteins,

74 ewise, serves as a ligand for the activating immunoreceptor natural killer group 2, D (NKG2D), also e

75 In contrast, the ligands of the activating immunoreceptor NKG2D (NKG2DL) are selectively expressed

76 express ligands for the natural killer cell immunoreceptor NKG2D, which sensitizes to early recognit

77 The immunoreceptors NKG2D and NKp46 are known for their capa

78 tion from disorder to order upon binding its immunoreceptor, NKG2D.

79 a secretome library, we found that the human immunoreceptor NKp44, encoded by NCR2 and expressed on n

80 h as tartrate-resistant acid phosphatase and immunoreceptor OCL-associated receptor, which are known

81 we show that mice lacking CD84-a homophilic immunoreceptor of the SLAM (signaling lymphocyte activat

82 leotide binding leucine-rich repeat (NB-LRR) immunoreceptors recognize specific pathogen effectors di

83 gulation in which engagement of a macrophage immunoreceptor recruits a stimulatory G protein-coupled

84 ngaging and activating the LAIR-1 inhibitory immunoreceptor represents a non-complement mechanism for

85 However, targeted activation of the innate immunoreceptor RIG-I initiated de novo HLA-I APM transcr

86 is that modification at one site changes the immunoreceptor's entropy, which in turn changes further

87 Thus, immunoreceptor sensing of SFK activity is a complex proc

88 ractions are strikingly similar to mammalian immunoreceptor-SFK-Syk signalling events in mammalian my

89 hich then enlists selected components of the immunoreceptor signaling cascade to transmit amplificati

90 The role of PAG as a negative regulator of immunoreceptor signaling has been examined in several mo

91 yrosine kinase, is an important component of immunoreceptor signaling in hematopoietic cells.

92 natural allelic variation in 5 genes of the immunoreceptor signaling pathway (IgH, Dok3, Src, Syk, a

93 vely regulating Src family kinases (SFKs) in immunoreceptor signaling pathways in B cells and macroph

94 rosine kinase (SYK) has an important role in immunoreceptor signaling, and SYK inhibition has accordi

95 vious data have reported that SLAP regulates immunoreceptor signaling.

96 nd myeloid lineage development and defective immunoreceptor signaling.

97 anisms may be an important factor modulating immunoreceptor signaling.

98 sequently, our results suggest that adaptive immunoreceptor-signaling pathways important in distingui

99 rovide insight into the interactions between immunoreceptor signals in a human cancer microenvironmen

100 n that interacts with the myeloid inhibitory immunoreceptor SIRPalpha (also termed CD172a or SHPS-1).

101 osis through interaction with the inhibitory immunoreceptor SIRPalpha expressed by macrophages.

102 its counter-receptor, the myeloid inhibitory immunoreceptor SIRPalpha.

103 tions in signaling initiated from activating immunoreceptors such as B cell Ag receptor.

104 After the engagement of immunoreceptors such as T-cell and B-cell antigen recept

105 Although signal transduction by immunoreceptors such as the T cell antigen receptor (TCR

106 to tyrosine-phosphorylated ITAM subunits of immunoreceptors, such as FcepsilonRI on mast cells, resu

107 ation and T cell recognition proposes innate immunoreceptor targeting as a strategy to overcome intri

108 Thus, CEACAM2 is a novel platelet immunoreceptor that acts as a negative regulator of plat

109 NKG2D is a potent activating immunoreceptor that has emerged as an important player i

110 yte antigen 4 (CTLA4) encodes a coinhibitory immunoreceptor that is a key regulator of self-tolerance

111 Identification of the immunoreceptors that bind SP-D is essential for understa

112 (PDCD1) are two genes encoding coinhibitory immunoreceptors that harbor polymorphisms with demonstra

113 ignaling: signals initiated by engagement of immunoreceptors that lead to conformational changes and

114 engagement of G-protein-coupled receptors or immunoreceptors, the extracellular domains of L-selectin

115 urrently associates with distinct inhibitory immunoreceptors to produce C1q-mediated modulatory netwo

116 nt solution NMR structure of the DAP12-NKG2C immunoreceptor transmembrane helix complex, five functio

117 Here we report that platelet immunoreceptor tyrosine activation motif (ITAM) signalin

118 Many of them are immunoreceptor tyrosine inhibitory motif (ITIM)-containi

119 2 intracytoplasmic tyrosine residues called immunoreceptor tyrosine inhibitory motifs.

120 at DNAM-1 promotes NK cell activation via an immunoreceptor tyrosine tail (ITT)-like motif coupling D

121 greatly reduce beta-glucan-induced Dectin-1 immunoreceptor tyrosine-based activating motif (ITAM) ph

122 To test the role of Src family kinases and immunoreceptor tyrosine-based activating motif (ITAM)-co

123 ransfected cells required the presence of an immunoreceptor tyrosine-based activating motif-bearing a

124 ins interacting with a doubly phosphorylated immunoreceptor tyrosine-based activation motif (dp-ITAM)

125 2 mediates platelet activation through a hem-immunoreceptor tyrosine-based activation motif (hemITAM)

126 single cytoplasmic YxxL motif known as a hem immunoreceptor tyrosine-based activation motif (hemITAM)

127 it is the only one to signal through a hemi-immunoreceptor tyrosine-based activation motif (hemITAM)

128 ic sequence motif of NKp65 resembling a hemi-immunoreceptor tyrosine-based activation motif (hemITAM)

129 induced IL-4 production was dependent on the immunoreceptor tyrosine-based activation motif (ITAM) ad

130 osphorylated DAP12, an adaptor containing an immunoreceptor tyrosine-based activation motif (ITAM) an

131 release in response to stimulation of (hem) immunoreceptor tyrosine-based activation motif (ITAM) an

132 in kinase C, all downstream mediators of the immunoreceptor tyrosine-based activation motif (ITAM) ca

133 ough activating Fcgamma receptors bearing an immunoreceptor tyrosine-based activation motif (ITAM) in

134 lian Syk and Zap-70, binds Draper through an immunoreceptor tyrosine-based activation motif (ITAM) in

135 kinase activity and consequent to biased BCR immunoreceptor tyrosine-based activation motif (ITAM) mo

136 ously quantitated the phosphorylation of the immunoreceptor tyrosine-based activation motif (ITAM) of

137 et glycoprotein receptors that signal via an immunoreceptor tyrosine-based activation motif (ITAM) or

138 he B cell antigen receptor (BCR) via the non-immunoreceptor tyrosine-based activation motif (ITAM) ph

139 duces receptor oligomerization, Igalpha/beta immunoreceptor tyrosine-based activation motif (ITAM) ph

140 Previously, we had shown that activation of immunoreceptor tyrosine-based activation motif (ITAM) pr

141 y to associate with c-Src is mediated by the immunoreceptor tyrosine-based activation motif (ITAM) pr

142 in that triggers platelet activation through immunoreceptor tyrosine-based activation motif (ITAM) si

143 rment of differentiation required the PY and immunoreceptor tyrosine-based activation motif (ITAM) si

144 ine kinase family plays an essential role in immunoreceptor tyrosine-based activation motif (ITAM) si

145 Somatic mutations affecting the immunoreceptor tyrosine-based activation motif (ITAM) si

146 osphorylated on two tyrosine residues of the immunoreceptor tyrosine-based activation motif (ITAM), l

147 d by 2 receptors that signal through an (hem)immunoreceptor tyrosine-based activation motif (ITAM), t

148 ng pathway that relies on a highly conserved immunoreceptor tyrosine-based activation motif (ITAM), w

149 Unexpectedly, however, immunoreceptor tyrosine-based activation motif (ITAM)- a

150 In contrast, deficiency in the immunoreceptor tyrosine-based activation motif (ITAM)-co

151 An important function of immunoreceptor tyrosine-based activation motif (ITAM)-co

152 that a signaling pathway mediated by the DC immunoreceptor tyrosine-based activation motif (ITAM)-co

153 target cell interactions or ligation of the immunoreceptor tyrosine-based activation motif (ITAM)-co

154 NK cell-activating receptors signal through immunoreceptor tyrosine-based activation motif (ITAM)-co

155 Immunoreceptor tyrosine-based activation motif (ITAM)-co

156 te that a signaling pathway initiated by the immunoreceptor tyrosine-based activation motif (ITAM)-co

157 Immunoreceptor tyrosine-based activation motif (ITAM)-co

158 rs have been shown to inhibit signaling from immunoreceptor tyrosine-based activation motif (ITAM)-co

159 mmatory disease, which signal through a (hem)immunoreceptor tyrosine-based activation motif (ITAM)-de

160 receptors inhibit cellular responsiveness to immunoreceptor tyrosine-based activation motif (ITAM)-li

161 ike protein 5 (FCRL5) on B cells has both an immunoreceptor tyrosine-based activation motif (ITAM)-li

162 show that although CD45 is necessary for all immunoreceptor tyrosine-based activation motif (ITAM)-sp

163 tyrosine residues arranged in a noncanonical immunoreceptor tyrosine-based activation motif (ITAM).

164 nd the Fc receptor gamma-chain, which has an immunoreceptor tyrosine-based activation motif (ITAM).

165 motes engulfment of axonal debris through an immunoreceptor tyrosine-based activation motif (ITAM).

166 izes two tandem YXXL repeats presented as an immunoreceptor tyrosine-based activation motif (ITAM).

167 gnaling, including CD79a, a protein with the immunoreceptor tyrosine-based activation motif (ITAM).

168 receptor 2 (CLEC-2), which signal through an immunoreceptor tyrosine-based activation motif (ITAM).

169 d a previously unrecognized carboxy-terminal immunoreceptor tyrosine-based activation motif (ITAM).

170 C: central supramolecular activation cluster Immunoreceptor tyrosine-based activation motif (ITAM): a

171 With the use of a phosphorylated immunoreceptor tyrosine-based activation motif (pITAM) p

172 intracytoplasmic tails (FcgammaRIIa with an immunoreceptor tyrosine-based activation motif [ITAM] an

173 ytokine receptor-mediated responses, whereas immunoreceptor tyrosine-based activation motif containin

174 Here, we show that CARs encoding a single immunoreceptor tyrosine-based activation motif direct T

175 While it contains an immunoreceptor tyrosine-based activation motif in its cy

176 have also determined that an intact FcgammaR immunoreceptor tyrosine-based activation motif is requir

177 Conversely, Y188F mutation in the immunoreceptor tyrosine-based activation motif of CD79A

178 III, and IV induces cell activation via the immunoreceptor tyrosine-based activation motif on the co

179 showed that both tyrosines of the CD3epsilon immunoreceptor tyrosine-based activation motif partition

180 itogen-activated protein kinase pathway, the immunoreceptor tyrosine-based activation motif pathway,

181 receptors in hemostasis, the contribution of immunoreceptor tyrosine-based activation motif receptors

182 3 glycoproteins that belong to the family of immunoreceptor tyrosine-based activation motif receptors

183 re synergistic and CAR specific and required immunoreceptor tyrosine-based activation motif signaling

184 to summarize recent findings on how platelet immunoreceptor tyrosine-based activation motif signaling

185 ever, have identified new roles for platelet immunoreceptor tyrosine-based activation motif signaling

186 al an important contribution of Grb2 in (hem)immunoreceptor tyrosine-based activation motif signaling

187 at Grb2 is a crucial adapter protein in (hem)immunoreceptor tyrosine-based activation motif signaling

188 In vivo, this selective (hem)immunoreceptor tyrosine-based activation motif signaling

189 that CLP36 acts as a major inhibitor of GPVI immunoreceptor tyrosine-based activation motif signaling

190 veal an inhibitory function of CLP36 in GPVI immunoreceptor tyrosine-based activation motif signaling

191 (BCR), and its cytoplasmic tail contains an immunoreceptor tyrosine-based activation motif that can

192 Phosphorylation of the conserved immunoreceptor tyrosine-based activation motif tyrosines

193 Mechanistically, the LMP2A immunoreceptor tyrosine-based activation motif was criti

194 d cytoplasmic domain, inclusive of the ITAM (immunoreceptor tyrosine-based activation motif) involved

195 acids in a sequence known as a hemITAM (hemi-immunoreceptor tyrosine-based activation motif).

196 y receptors that have 1 or more copies of an immunoreceptor tyrosine-based activation motif, defined

197 nsduced phosphorylation of its intracellular immunoreceptor tyrosine-based activation motif, which in

198 all-trans-retinoic acid treatment or active immunoreceptor tyrosine-based activation motif-bearing (

199 in receptors, such as Ly49H, associated with immunoreceptor tyrosine-based activation motif-bearing a

200 naling as well as costimulatory signals from immunoreceptor tyrosine-based activation motif-containin

201 s, including the integrin alphaIIbbeta3, the immunoreceptor tyrosine-based activation motif-containin

202 The hemi-immunoreceptor tyrosine-based activation motif-containin

203 prevent inflammatory bleeding through (hem) immunoreceptor tyrosine-based activation motif-dependent

204 latory signal that prevents expression of an immunoreceptor tyrosine-based activation motif-free IgE

205 (NFATc1, RANK, costimulatory receptors, and immunoreceptor tyrosine-based activation motif-harboring

206 lucan component of yeast is dependent on the immunoreceptor tyrosine-based activation motif-like doma

207 Lyn Src-family kinase with an intracellular immunoreceptor tyrosine-based activation motif-like sequ

208 ation of two tyrosine residues located in an immunoreceptor tyrosine-based activation motif-like sequ

209 e evident despite a severe impairment of the immunoreceptor tyrosine-based activation motif-mediated

210 ytotoxicity via an atypical cytoplasmic hemi-immunoreceptor tyrosine-based activation motif.

211 am of the Fc receptor gamma-chain-associated immunoreceptor tyrosine-based activation motif.

212 platelet activation that both signal via an immunoreceptor tyrosine-based activation motif.

213 tetherin cytoplasmic tail resembles the hemi-immunoreceptor tyrosine-based activation motifs (hemITAM

214 SFKs are key kinases phosphorylating immunoreceptor tyrosine-based activation motifs (ITAM) i

215 Immunoreceptor tyrosine-based activation motifs (ITAMs)

216 Adaptor molecules bearing immunoreceptor tyrosine-based activation motifs (ITAMs)

217 icate balance between receptors that contain immunoreceptor tyrosine-based activation motifs (ITAMs)

218 with each receptor independently through the immunoreceptor tyrosine-based activation motifs (ITAMs)

219 nt function of receptors that signal through immunoreceptor tyrosine-based activation motifs (ITAMs)

220 responses depends on the phosphorylation of immunoreceptor tyrosine-based activation motifs (ITAMs)

221 Clustering of receptors associated with immunoreceptor tyrosine-based activation motifs (ITAMs)

222 ceptor signaling through adaptors containing immunoreceptor tyrosine-based activation motifs (ITAMs),

223 elopment can proceed with as few as 4/10 CD3 immunoreceptor tyrosine-based activation motifs (ITAMs),

224 c-family kinases (SFKs), which phosphorylate immunoreceptor tyrosine-based activation motifs (ITAMs),

225 orylated by the phosphatase CD45 on multiple immunoreceptor tyrosine-based activation motifs (ITAMs).

226 complex is unique in having ten cytoplasmic immunoreceptor tyrosine-based activation motifs (ITAMs).

227 e regulated by receptors that signal through immunoreceptor tyrosine-based activation motifs (ITAMs).

228 a tandem SH2 unit responsible for binding to immunoreceptor tyrosine-based activation motifs (ITAMs).

229 0 sites that are distributed on 10 conserved immunoreceptor tyrosine-based activation motifs (ITAMs).

230 equirements for a large number of functional immunoreceptor tyrosine-based activation motifs (ITAMs;

231 nRI alpha-chains induces cell activation via immunoreceptor tyrosine-based activation motifs in assoc

232 Its zeta-subunit contains multiple cytosolic immunoreceptor tyrosine-based activation motifs involved

233 CD28 and active immunoreceptor tyrosine-based activation motifs were cri

234 ly by two amino acid sequence motifs, ITAMs (immunoreceptor tyrosine-based activation motifs) and ITI

235 sphotyrosines within FcepsilonRIgamma-ITAMs (immunoreceptor tyrosine-based activation motifs).

236 integrin Mac-1 and utilize signals involving immunoreceptor tyrosine-based activation motifs.

237 sphorylated tyrosines within the FcepsilonRI immunoreceptor tyrosine-based activation motifs.

238 cyt apparently controls accessibility of the immunoreceptor tyrosine-based activation signal transduc

239 dues, but none of the Tyr residues match the immunoreceptor tyrosine-based activation, inhibitory, or

240 the cytoplasmic domains of gB (gBcyt) via an immunoreceptor tyrosine-based inhibition motif (ITIM) an

241 The present study identifies a canonical immunoreceptor tyrosine-based inhibition motif (ITIM) in

242 tor pair that recruited components to CD33's immunoreceptor tyrosine-based inhibition motif (ITIM), i

243 brane receptor-like protein that contains an immunoreceptor tyrosine-based inhibition motif (ITIM), w

244 The immunoreceptor tyrosine-based inhibition motif (ITIM)-co

245 Since their discovery, immunoreceptor tyrosine-based inhibition motif (ITIM)-co

246 ealed that these processes require the ITIM (immunoreceptor tyrosine-based inhibition motif) of the r

247 This immunoreceptor tyrosine-based inhibition motif-bearing r

248 Deletion of the immunoreceptor tyrosine-based inhibition motif-containin

249 are controlled by receptors with cytoplasmic immunoreceptor tyrosine-based inhibition motifs (ITIMs).

250 Both CD31 intracellular immunoreceptor tyrosine-based inhibition motifs are requ

251 In contrast, mice with mutated CD22 immunoreceptor tyrosine-based inhibition motifs have inc

252 Phosphorylation of immunoreceptor tyrosine-based inhibition motifs in its c

253 at least in part, because the phosphorylated immunoreceptor tyrosine-based inhibition motifs recruit

254 intracellular region of LAIR-1 contains two immunoreceptor tyrosine-based inhibition motifs that are

255 s), dampening immune responses via cytosolic immunoreceptor tyrosine-based inhibition motifs that rec

256 tyrosine-based activation motifs) and ITIMs (immunoreceptor tyrosine-based inhibition motifs) that ac

257 b is an inhibitory platelet receptor with an immunoreceptor tyrosine-based inhibitory motif (ITIM) an

258 CD300a is an immunoreceptor tyrosine-based inhibitory motif (ITIM) co

259 The cytoplasmic tail of PD-1 contains an immunoreceptor tyrosine-based inhibitory motif (ITIM) en

260 ock-in mouse with a targeted mutation in the immunoreceptor tyrosine-based inhibitory motif (ITIM) of

261 RIIb on the surface of B cells, resulting in immunoreceptor tyrosine-based inhibitory motif (ITIM) ph

262 We show that vGPCR contains a bona fide immunoreceptor tyrosine-based inhibitory motif (ITIM) th

263 Immunoreceptor tyrosine-based inhibitory motif (ITIM)-co

264 I signaling through a previously undescribed immunoreceptor tyrosine-based inhibitory motif (ITIM)-li

265 ivation motif [ITAM] and FcgammaRIIb with an immunoreceptor tyrosine-based inhibitory motif [ITIM]).

266 ppressive receptor T-cell immunoglobulin and immunoreceptor tyrosine-based inhibitory motif domain (T

267 CRP-induced increases in FcgammaRIIB immunoreceptor tyrosine-based inhibitory motif phosphory

268 riable domain, a transmembrane domain and an immunoreceptor tyrosine-based inhibitory motif that was

269 ptor Fcgamma receptor IIB (FcgammaRIIB), its immunoreceptor tyrosine-based inhibitory motif, and SH2

270 We found the immunoreceptor tyrosine-based inhibitory motif-containin

271 osine phosphatase 1 (SHP-1) to a cytoplasmic immunoreceptor tyrosine-based inhibitory motif.

272 -transduced HEK293T cells required an intact immunoreceptor tyrosine-based inhibitory motif.

273 motif (ITAM)-like sequence and two consensus immunoreceptor tyrosine-based inhibitory motifs (ITIM) i

274 lagen tail trigger phosphorylation of LAIR-1 immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

275 ivity to LM infection, while mutation of its immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

276 o SHP-1 and SHP-2 after phosphorylation of 2 immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

277 oglobulin-like (IgL) domains and cytoplasmic immunoreceptor tyrosine-based inhibitory motifs (ITIMs)

278 vation motifs (ITAMs) and those that contain immunoreceptor tyrosine-based inhibitory motifs (ITIMs).

279 latelet immunoglobulin receptor that has two immunoreceptor tyrosine-based inhibitory motifs in its c

280 tation of the conserved tyrosines in the two immunoreceptor tyrosine-based inhibitory motifs prevents

281 esults in phosphorylation of the cytoplasmic immunoreceptor tyrosine-based inhibitory motifs, resulti

282 dhesive and signaling properties mediated by immunoreceptor tyrosine-based inhibitory motifs.

283 domain superfamily protein with cytoplasmic immunoreceptor tyrosine-based inhibitory motifs.

284 bitory motif (ITIM) encompassing Y223 and an immunoreceptor tyrosine-based switch motif (ITSM) encomp

285 yrosine-based inhibitory motif (ITIM) and an immunoreceptor tyrosine-based switch motif (ITSM).

286 LILRB1, which contains an immunoreceptor tyrosine-based switch motif, functions he

287 CS1-L contains immunoreceptor tyrosine-based switch motifs in its cytop

288 on in a SAP-dependent manner, requiring both immunoreceptor tyrosine-based switch motifs in the NTB-A

289 n its cytoplasmic domain whereas CS1-S lacks immunoreceptor tyrosine-based switch motifs.

290 complex contains 10 copies of a di-tyrosine Immunoreceptor-Tyrosine-based-Activation-Motif (ITAM) th

291 Clustering of immunoreceptors upon association with multivalent ligand

292 ing lymphocyte activation molecule family of immunoreceptors, which self-associates, forming an ortho

293 mined by the collective signals from various immunoreceptors, whose expression and activity depend on

294 Thus, Draper seems to be an ancient immunoreceptor with an extracellular domain tuned to mod

295 1 (DNAM-1), CD96 molecule (CD96), and T-cell immunoreceptor with Ig and ITIM domains (TIGIT) play a c

296 ceptors programmed death-1 (PD-1) and T cell immunoreceptor with Ig and ITIM domains (TIGIT) were com

297 injections of antibodies against PD1, T-cell immunoreceptor with Ig and ITIM domains (TIGIT), or CD8

298 hocyte associated gene 3 (LAG-3), and T cell immunoreceptor with Ig and ITIM domains (TIGIT).

299 in-containing molecule 3), and TIGIT (T-cell immunoreceptor with immunoglobulin and ITIM domains) act

300 arliest events of immune cell activation via immunoreceptors with unexplained specificity and speed.