ライフサイエンスコーパス: immunostimulatory

1 ase pairs (bp) in length has been considered immunostimulatory.

2 acrophages and that these ssDNAs were highly immunostimulatory.

3 issle 1917 and Thermus thermophilus were non-immunostimulatory.

4 phocytes in order to evaluate their possible immunostimulatory abilities.

5 Whilst the mechanism behind its immunostimulatory action is not fully understood, the ab

6 nhibition in TAMs induced an angiostatic and immunostimulatory activation with potential therapeutic

7 ion parvoviruses with enhanced oncolytic and immunostimulatory activities and rational combination of

8 ies of hIL-10 but lost the ability to induce immunostimulatory activities on some cells.

9 HDE immunostimulatory activities predicted the aeroallergen

10 transgenes that augment their cytotoxic and immunostimulatory activities, and modulate the tumour mi

11 adjuvants have shown significantly different immunostimulatory activities, suggesting that the struct

12 whose levels did not correlate exactly with immunostimulatory activities.

13 opment, depending on their host-damaging and immunostimulatory activities.

14 destabilize double-stranded RNA reducing its immunostimulatory activities.

15 ric cytokine with both immunosuppressive and immunostimulatory activities; however, IL-10-based thera

16 , Ca(2+), HMDM) with comparable efficacy and immunostimulatory activity as that of C3a in activating

17 diated XBP1 silencing in tDCs restored their immunostimulatory activity in situ and extended survival

18 in receptor-deficient mice revealed that the immunostimulatory activity of SLP-8321 depends on its re

19 The immunostimulatory activity of these compounds was also o

20 This endogenous immunostimulatory activity required nucleic acid and pro

21 4 ligation, and stronger proinflammatory and immunostimulatory activity than wild-type (WT) liver mDC

22 The dependence on FcgammaRIIB for immunostimulatory activity was not absolute, however, be

23 In order to correlate bioactive content with immunostimulatory activity we compared the abilities of

24 lecular components of Wigglesworthia exhibit immunostimulatory activity within tsetse is representati

25 ver targeting, increased half-life, enhanced immunostimulatory activity, and reduced cytotoxicity.

26 owever, the honeys differed greatly in their immunostimulatory activity, even within the same honey t

27 Because of their immunostimulatory activity, several TLR agonists are bei

28 new type of pathobionts that possess strong immunostimulatory activity, which is critical for alveol

29 8 (TLR7/8) agonist with potent antitumor and immunostimulatory activity.

30 PC function, GM-CSF is being evaluated as an immunostimulatory adjuvant in a number of clinical trial

31 umor antigen material together with a highly immunostimulatory adjuvant.

32 Interestingly, beryllium did not act as an immunostimulatory agent as it does in Anurans and mammal

33 is demonstrated that monotherapy using this immunostimulatory agent significantly suppresses the tum

34 r the therapeutic efficacy of a new systemic immunostimulatory agent, the Toll-like receptor-7 (TLR7)

35 ficant interest in targeting MAIT cells with immunostimulatory agents to enhance immune responses.

36 rrently used in the clinic: cancer vaccines, immunostimulatory agents, adoptive T cell therapy, and i

37 , a US Food and Drug Administration-approved immunostimulatory agonist for Toll-like receptor-4, prom

38 Altogether, the results describe a novel immunostimulatory agonist targeted to the cytosolic RIG-

39 Immunostimulatory agonists such as anti-CD137 and interl

40 r microenvironment from immunosuppressive to immunostimulatory and contributed to inhibition of ovari

41 neable sequence and combined gene silencing, immunostimulatory and cytotoxic capacity of p-shRNA make

42 ppropriate ORs, conflicting reports indicate immunostimulatory and immunosuppressive activity, in tha

43 cular, we discuss the antagonism between the immunostimulatory and immunosuppressive effects of RT as

44 r cell lines, offering a route to decoupling immunostimulatory and immunosuppressive functions of IFN

45 A delicate balance between immunostimulatory and immunosuppressive signals mediated

46 However, IFN signaling can be both immunostimulatory and immunosuppressive, and the factors

47 dulating immune responses on an axis between immunostimulatory and immunosuppressive.

48 hese data show that concomitant targeting of immunostimulatory and inhibitory checkpoints with immuno

49 postulate that an intricate balance between immunostimulatory and inhibitory DAMPs could determine t

50 lipids, or as a variant lacking GPL which is immunostimulatory and invasive in macrophage infection m

51 CpG(A)-STAT3 siRNA is immunostimulatory and nontoxic for normal human leukocyt

52 unity in patients with COPD by examining the immunostimulatory and tolerogenic properties of pulmonar

53 ors is a primary obstacle to the efficacy of immunostimulatory and vaccine approaches.

54 The combination of radiotherapy with immunostimulatory anti-PD1 and anti-CD137 mAbs was condu

55 In patients with RRMM, elotuzumab, an immunostimulatory antibody, appears to provide clinical

56 ture of Rv0315 at 1.70 A resolution, a novel immunostimulatory antigen of Mtb, and demonstrate that R

57 ion, tRNA(Tyr) from Escherichia coli was not immunostimulatory, as were all tested eukaryotic tRNAs.

58 ion of Panx1 channels drives accumulation of immunostimulatory ATP versus immunosuppressive adenosine

59 Gs significantly overexpress mRNA of various immunostimulatory bactericidal proteins and alarmins, re

60 l mucosal RSV F protein vaccine linked to an immunostimulatory bacterium-like particle (BLP).Methods:

61 response was induced by surface exposure of immunostimulatory beta-glucans and was mediated by activ

62 ced by other factors, including unidentified immunostimulatory bioactives and immunosuppressive compo

63 nflammasome assembly and activation, and the immunostimulatory capacity and apoptotic predilection of

64 These data highlight the potential immunostimulatory capacity of a group of novel drugs, sr

65 uction by ECP and offer new insight into the immunostimulatory capacity of ECP.

66 Thus, the potent immunostimulatory capacity of IL-10-deficient DCs is due

67 esis and may have implications regarding the immunostimulatory capacity of RNAP III transcripts.

68 Herein, we increased the immunostimulatory capacity of SPIONs by coating them wit

69 ation, PGE(2) has unfavorable effects on the immunostimulatory capacity of these cells.

70 these data indicate that mCD40L enhances the immunostimulatory capacity over sCD40L.

71 ere was to determine the characteristics and immunostimulatory capacity, in vivo, of antigen and adju

72 e, csa1 copy number variants differ in their immunostimulatory capacity, revealing a mechanism by whi

73 optosis inducers but might also change their immunostimulatory capacity.

74 cipitation of infected cell lysates isolated immunostimulatory CCHFV RNA.

75 rt the unexpected finding that proliferating immunostimulatory CD11c(+) MHC class II(+) cDCs derived

76 resence and activity of immunosuppressive or immunostimulatory cell types in glioblastoma tumors, inc

77 transformed from immunosuppressive to highly immunostimulatory cells capable of triggering potent ant

78 ng-term functional memory following a single immunostimulatory challenge, leading to enhanced product

79 on other subsequent, and temporally distant, immunostimulatory challenges.

80 beta-cells; induced exosomal release of the immunostimulatory chaperones calreticulin, Gp96, and ORP

81 al release of intracellular autoantigens and immunostimulatory chaperones may play a role in the init

82 olorectal cancer via systemic delivery of an immunostimulatory chemotherapeutic combination in nanosc

83 yinosinic:polycytidylic acid (poly I:C), and immunostimulatory complexes (ISCOMs).

84 This study is the first to reveal the immunostimulatory component of wheatgrass with well defi

85 erived from the outer membrane, they contain immunostimulatory components, especially lipopolysacchar

86 They differed in their contents of immunostimulatory components, including apalbumins, arab

87 s a major periodontal pathogen that contains immunostimulatory components.

88 ke receptor (TLR)4 agonists are known potent immunostimulatory compounds.

89 rs enhanced the in vivo antitumor effects of immunostimulatory CpG DNA; however, TIM-3 overexpression

90 all interfering RNAs, and miRNAs, constitute immunostimulatory CpG motifs as an integral part of thei

91 tion with an oligodeoxynucleotide containing immunostimulatory CpG motifs, these Ags induce, in mice

92 lease tumor associated antigens and delivers immunostimulatory CpG oligodeoxynucleotides to DCs.

93 Immunostimulatory CpG oligonucleotides (ODN) activate ce

94 acteriophage capsid protein encapsulating an immunostimulatory CpG-A oligodeoxynucleotide TLR9 agonis

95 tudy show the potential of using tumoricidal/immunostimulatory CpG-siRNA oligonucleotides as a novel

96 unized with F and G proteins adjuvanted with immunostimulatory (CpG) oligodeoxyribonucleotides admixe

97 ion of a costimulatory molecule (4-1BBL) and immunostimulatory cytokine (IL-12).

98 IL2 is an immunostimulatory cytokine for key immune cells includin

99 Among immunotherapeutic strategies, the immunostimulatory cytokine IL-15 could represent a serio

100 CP promotes marked release of the prototypic immunostimulatory cytokine IL-1beta.

101 anism, we evaluated NK cell responses to the immunostimulatory cytokine IL12.

102 dy-cytokine fusion protein consisting of the immunostimulatory cytokine interleukin-2 (IL-2) genetica

103 The immunostimulatory cytokine interleukin-2 (IL-2) is a gro

104 We reported that the immunostimulatory cytokine LIGHT (TNFSF14) in the microe

105 IL15, a potent immunostimulatory cytokine, both potentiates host T-cell

106 mokine ligand 17, and down-regulation of the immunostimulatory cytokine, IL-12.

107 okines, where the antibodies are fused to an immunostimulatory cytokine, such as interleukin 12 (IL-1

108 t upon specific recognition of TEM8 secreted immunostimulatory cytokines and killed tumor endothelial

109 Increased production of immunostimulatory cytokines in subjects carrying the hig

110 cytotoxic effect, were properly activated by immunostimulatory cytokines, and degranulated in the pre

111 arkers and produced large amounts of several immunostimulatory cytokines.

112 ry DAMP to counterpoise the adjuvanticity of immunostimulatory DAMPs.

113 d reciprocal effects on suppressive MDSC and immunostimulatory DC expansion.

114 Immunostimulatory DCs are highly desired for the develop

115 ion, the ability of NK1R agonists to promote immunostimulatory DCs remains unexplored.

116 ata demonstrate that NK1R signaling promotes immunostimulatory DCs, and provide relevant insight into

117 nderstanding of the mechanisms and impact of immunostimulatory defective viral genomes generated duri

118 These immunostimulatory defects are diverse and include mutati

119 itional therapies have targeted T cells, yet immunostimulatory dendritic cells (DCs) are critical in

120 or-associated macrophages (TAMs) rather than immunostimulatory dendritic cells (DCs) remains unclear.

121 tly colocalized with non-CpG double-stranded immunostimulatory DNA (ISD).

122 FN-inducible protein 16 (IFI16), which bound immunostimulatory DNA directly and activated the stimula

123 micronuclei represent an important source of immunostimulatory DNA.

124 A, and TREX1 KO enabled cells to sense short immunostimulatory DNA.

125 V NP and L protein were required to restrict immunostimulatory dsRNA accumulation.

126 hrough which LASV NP degrades virus-derived, immunostimulatory dsRNA in biochemical assays to elimina

127 V NP has been shown to degrade virus-derived immunostimulatory dsRNA in biochemical assays.

128 Together, our data suggest HDACi are immunostimulatory during cancer treatment and that combi

129 Thus, PD-L1 exerts an immunostimulatory effect by repressing the CTLA-4 axis;

130 The mechanism behind the immunostimulatory effect of the cationic liposomal vacci

131 Moreover, a similar immunostimulatory effect was observed when the CD1d upre

132 , they demonstrated distinct yet overlapping immunostimulatory effects due to the presence of virus R

133 nding that many chemotherapeutic agents have immunostimulatory effects has provided the impetus to co

134 rastuzumab, as both compounds mediated their immunostimulatory effects in strict dependence of target

135 nomodulatory actions are partly mediated via immunostimulatory effects in the liver.

136 discuss preclinical and clinical data on the immunostimulatory effects of conventional chemotherapeut

137 reveals a key role for Bacteroidales in the immunostimulatory effects of CTLA-4 blockade.

138 Antihistone IgG, which neutralizes the immunostimulatory effects of histones, suppressed intrar

139 In addition to well-established immunostimulatory effects of the microbiota, the presenc

140 Therefore, AHCC exerts immunostimulatory effects on intestinal epithelial cells

141 Thus, LGG+Bb12 induced systemic Th1 immunostimulatory effects on oral AttHRV vaccine that co

142 ffects on tumor cells as well as by indirect immunostimulatory effects on T and NK cells.

143 tumors can provoke parallel tumoricidal and immunostimulatory effects that bridge innate and adaptiv

144 has the potential ability to mediate robust immunostimulatory effects that could synergise with immu

145 LPS exerts potent immunostimulatory effects through activation of the TLR4

146 RNA molecules can cause potent cytotoxic and immunostimulatory effects through the activation of patt

147 ed cytosine/guanine (CpG) motifs, has potent immunostimulatory effects when coadministered with NY-ES

148 resulting in both cell autonomous as well as immunostimulatory effects.

149 re various species have different per capita immunostimulatory effects.

150 tone release during GN elicits cytotoxic and immunostimulatory effects.

151 has been suggested that some AGEs could have immunostimulatory effects.

152 n immune cells mediating proinflammatory and immunostimulatory effects.

153 ysteine (Pam(2)Cys) motif and exhibit potent immunostimulatory effects.

154 in malignant cells but also from a range of immunostimulatory effects.

155 erative, antiangiogenic, antimetastatic, and immunostimulatory effects.

156 lting in the elevation of exosome-associated immunostimulatory endogenous danger/damage associated mo

157 depletion of CD20(+) B cells creates a less immunostimulatory environment in the SLO reflected by re

158 higher amounts of potential celiac disease's immunostimulatory epitopes when compared to modern varie

159 a host response by sequestration of induced immunostimulatory ERV dsRNAs.

160 Strong immunostimulatory events such as immunotherapy or infect

161 These islet MSC-like cells release highly immunostimulatory EXOs that could activate autoreactive

162 ed, thus allowing for controlled delivery of immunostimulatory factors and presentation of pathogen-a

163 Notably, when expressed in a more immunostimulatory form, the self-peptide inhibited the f

164 mune response to muramyl dipeptide (MDP), an immunostimulatory fragment of bacterial cell wall, but i

165 eta plays a unique role in DC maturation and immunostimulatory functionality and emerges as a key fac

166 rganisms to benefit from the antioxidant and immunostimulatory functions that carotenoids fulfill.

167 (CD80 and CD86) molecules and have impaired immunostimulatory functions, such as antigen uptake and

168 re capable of executing potent and immediate immunostimulatory functions.

169 kine secretion and cell death in response to immunostimulatory fungal components.

170 sequences by site-specific mutagenesis in an immunostimulatory gene promoter allows its transcription

171 some of the oncogenic/inflammatory and Th-1 immunostimulatory genes are differentially regulated in

172 growth while inhibiting its binding to Th-1 immunostimulatory genes in growing tumors, including in

173 y effective delivery platform for delivering immunostimulatory genes into the tumor microenvironment

174 associated carbohydrate antigens (TACAs) and immunostimulatory glycolipids that hold promise as immun

175 Additionally, in vitro methylation of this immunostimulatory Gm18-negative tRNA with recombinant tr

176 cellular matrix and secrete higher levels of immunostimulatory IL-12p70 while producing reduced level

177 Uromodulin/Tamm-Horsfall protein is not immunostimulatory in the tubular lumen, but through unkn

178 r microenvironment from immunosuppressive to immunostimulatory, increasing the efficacy of antitumour

179 rammed necrotic cell death causes release of immunostimulatory intracellular components after cell-me

180 P III), yet how these transcripts remain non-immunostimulatory is incompletely understood.

181 herical nucleic acids (SNAs) that stimulate (immunostimulatory, IS-SNA) or regulate (immunoregulatory

182 CD154 is an immunostimulatory ligand for CD40 that markedly influenc

183 focused on transcription induced by defined immunostimulatory ligands, such as lipopolysaccharide.

184 vicida represses expression of an endogenous immunostimulatory lipoprotein.

185 olarizes immunosuppressive M2 macrophages to immunostimulatory M1 macrophages, while alphaCD47 blocks

186 ge of the mechanisms of action of anti-CD137 immunostimulatory mAbs such as those currently undergoin

187 herapy can be synergistically augmented with immunostimulatory mAbs to act both on irradiated tumor l

188 -sized membrane vesicles that contain potent immunostimulatory materials.

189 , little is known regarding the induction of immunostimulatory mediators by ECP.

190 tic cells (DC) to selectively supplement the immunostimulatory miRNA miR-155.

191 racts with programmed death-1 (PD-1) and the immunostimulatory molecule CD80 and functions as a check

192 erived cyclic-di-AMP to be the key bacterial immunostimulatory molecule, the mechanism for IFNbeta ex

193 hods for colocalized delivery of antigen and immunostimulatory molecules (i.e., adjuvants) are needed

194 latory danger signals, arming the virus with immunostimulatory molecules can further improve efficacy

195 A can be exploited to generate a spectrum of immunostimulatory molecules for vaccine and therapeutics

196 immunity either by initiating the release of immunostimulatory molecules from dying cancer cells or b

197 antigens in the vesicle core and lipid-based immunostimulatory molecules in the vesicle walls under e

198 emerging evidence suggests that delivery of immunostimulatory molecules into tumors can have therape

199 inflammatory response through the actions of immunostimulatory molecules referred to as damage-associ

200 nd pathogen-derived nucleic acids are highly immunostimulatory molecules that play a major role in th

201 d by expansion of myeloid subsets expressing immunostimulatory molecules that promote improved T cell

202 NETs are toxic to the endothelium, expose immunostimulatory molecules, activate plasmacytoid dendr

203 n, in macrophages treated with LPS and other immunostimulatory molecules.

204 sses by refined adoptive T-cell transfer and immunostimulatory monoclonal Ab (mAbs).

205 pharmacodynamics and antitumor properties of immunostimulatory monoclonal antibodies (mAb) in setting

206 Elotuzumab, an immunostimulatory monoclonal antibody targeting signalli

207 screening tool for the synthesis of new non-immunostimulatory nanocarriers.

208 report the development of a dual-functional, immunostimulatory nanomicellar carrier that is based on

209 We developed a highly potent immunostimulatory nanoparticle (immuno-NP) to activate a

210 st handled by antigen-presenting cells as an immunostimulatory nanoparticle.

211 We hypothesized that these immunostimulatory nanoparticles could suppress tumor gro

212 , well tolerated, and systemically available immunostimulatory NCP promises to enter clinical testing

213 Rapid identification of immunostimulatory neoantigen targets hastens neoantigen

214 s and an enhanced type I IFN response to the immunostimulatory nucleic acid polyinosinic:polycytidyli

215 cuss here an unexpected source of endogenous immunostimulatory nucleic acids: the reverse-transcribed

216 ver, by incorporating tumor-homing peptides, immunostimulatory nucleotide-bearing nanoparticles facil

217 tive Hexose Correlated Compound (AHCC) is an immunostimulatory nutritional supplement.

218 The SNAs comprise immunostimulatory oligonucleotides (CpG-1826) as adjuvan

219 system capable of encapsulating an array of immunostimulatory oligonucleotides that, in some cases,

220 model of melanoma subject to treatment with immunostimulatory oncolytic viruses and dendritic cell v

221 ntal targeted anticancer agents also mediate immunostimulatory or immunosuppressive effects that (at

222 on for siRNA against nucleases without being immunostimulatory, or cytotoxic.

223 Host-damaging and immunostimulatory oral bacteria cooperatively induce bon

224 lated to vessel normalization correlate with immunostimulatory pathways, especially T lymphocyte infi

225 simultaneously reducing the accumulation of immunostimulatory peptidoglycan fragments in the host ce

226 correlated with global downregulation of DC immunostimulatory phenotype and function.

227 OX40+ pDCs were distinguished by a distinct immunostimulatory phenotype, cytolytic function, and abi

228 +)Gr1(+) cells in the pancreas to acquire an immunostimulatory phenotype.

229 ges from a suppressive to a proinflammatory, immunostimulatory phenotype.

230 1c(+) cells invaded by cps were converted to immunostimulatory phenotypes, which expressed increased

231 Here we determined whether immunostimulatory plant-derived arabinogalactan proteins

232 ols the maturation, cytokine production, and immunostimulatory potency of DCs--restricted systemicall

233 hough representative NANPs with high and low immunostimulatory potential are used as standards throug

234 We analyzed the immunostimulatory potential of transfer RNA (tRNA) from

235 ion provides a simple way of controlling the immunostimulatory potential, and physicochemical and del

236 Gm18)-2'-O-methyltransferase (trmH) regained immunostimulatory potential.

237 through regulatory mechanisms that limit the immunostimulatory presentation of self antigens.

238 istinction, however, is that RET/PTCs induce immunostimulatory programs, suggesting that, in the case

239 erent human cell lines and that have defined immunostimulatory properties confirmed by ex vivo experi

240 hetic CpG oligonucleotides (ODN) have potent immunostimulatory properties exploited in clinical vacci

241 te that CD20-targeted delivery overcomes the immunostimulatory properties of CpG-containing ON therap

242 Additionally, tunable immunostimulatory properties of described nanoparticles

243 s highlight the potential for harnessing the immunostimulatory properties of different adjuvants to d

244 In this study we describe the immunostimulatory properties of Enterococcus gallinarum

245 We suggest that the immunostimulatory properties of honey may be influenced

246 Analysis of the immunostimulatory properties of interleukin-12 and its d

247 Given the known immunostimulatory properties of MPL and QS-21, the objec

248 The rapid immunostimulatory properties of recombinant vesicular st

249 ications of similar approaches in overcoming immunostimulatory properties of RNA-directed therapeutic

250 Here, we compare the chemophysical and immunostimulatory properties of wild-type cowpea mosaic

251 In vitro evaluation of immunostimulatory properties revealed new potent TLR2 li

252 s (CpG ODN) are TLR9 ligands with attractive immunostimulatory properties, but intratumoral administr

253 Due to their potent interfering and immunostimulatory properties, DVGs may also be used ther

254 ing lipoplexes in gene therapy lies in their immunostimulatory properties, so far attributed to the n

255 TLR4, suggesting that MMTV intensifies these immunostimulatory properties.

256 ties of honey, and hence contribute to their immunostimulatory properties.

257 represents a novel TLR7 agonist with strong immunostimulatory properties.

258 g on dendritic cells (DCs) to diminish their immunostimulatory properties.

259 der cancer and other malignancies due to its immunostimulatory properties.

260 uide the design of live vaccines with strong immunostimulatory properties.IMPORTANCE Effectiveness of

261 Non-MTEX were enriched in immunostimulatory proteins (P = 0.002) and were only wea

262 omplex coacervates for sustained delivery of immunostimulatory proteins as an effective therapeutic s

263 Agonistic antibodies directed against immunostimulatory receptors belonging to the tumor necro

264 istic antibodies promoted antiangiogenic and immunostimulatory reprogramming of Prox1-deficient tumor

265 brary of aryl trehalose derivatives to drive immunostimulatory reresponses and evaluated the structur

266 The adverse immunostimulatory responses were abrogated by selective

267 gery, prevent immune suppression and enhance immunostimulatory responses.

268 s," could be designed to efficiently deliver immunostimulatory RNA (isRNA) to TLR-expressing cells to

269 tern-recognition receptors exist that detect immunostimulatory RNA and then induce cytokine-mediated

270 Immunostimulatory RNA was isolated from CCHFV-infected c

271 Toll-like receptor (TLR) 7 and 8 sensing of immunostimulatory RNA, independent of their miRNA-target

272 echanism for the intracellular metabolism of immunostimulatory RNA, with implications for specific au

273 Here we tested the immunostimulatory role of this lipid A modification.

274 oration of lipid A plays both protective and immunostimulatory roles and that host-derived CAMPs may

275 QS-21 is a potent immunostimulatory saponin that is currently under clinic

276 cks immunosuppressive apoptosis and promotes immunostimulatory secondary necrosis by binding to the p

277 These studies show that a weakly immunostimulatory self-peptide can induce thymic and per

278 Moreover, a strongly immunostimulatory self-peptide expressed by B cells indu

279 at a key subset of these ncRNAs functions as immunostimulatory "self-agonists" and directly activates

280 existing VLP vaccines not naturally carrying immunostimulatory sequences.

281 lation of DNA in the cytosol serves as a key immunostimulatory signal associated with infections, can

282 c by the host only when malignant cells emit immunostimulatory signals (so-called "damage-associated

283 response may be connected to the delivery of immunostimulatory signals to ensure the elimination of g

284 These findings suggest that the class of immunostimulatory siRNAs may benefit from activation of

285 , nanotechnology can enhance the efficacy of immunostimulatory small molecules and biologics by alter

286 ate sensors despite massive transcription of immunostimulatory small RNAs (EBV-EBERs).

287 ve NK cells had a reduced expression of NCR3 immunostimulatory splice variants and an increased expre

288 We previously developed an immunostimulatory strategy based on targeted Stat3 silen

289 ere it plays a key role in the activation of immunostimulatory T cells and acts as the primary recept

290 , supernatants from ruptured cells were more immunostimulatory than those from nonruptured cells.

291 Liver-resident pDCs are considerably less immunostimulatory than those from secondary lymphoid tis

292 e therapy in carefully selected patients and immunostimulatory therapies in others is the shortest pa

293 t infection of DCs with TriGAS may be highly immunostimulatory through mechanisms that enhance antige

294 These findings indicate that SIV encodes immunostimulatory TLR ligands and that pDC, mDC, and mon

295 Accordingly, DNPs lacking immunostimulatory TLR9 ligands in DNA stimulated IFN-alp

296 bits C/EBPbeta activation, thus promoting an immunostimulatory transcriptional program that restores

297 therapy has been proposed as an ablative and immunostimulatory treatment strategy for solid tumors th

298 tiviral defense genes not observed following immunostimulatory treatments or experimental infections

299 o occurred despite the continued presence of immunostimulatory viral Ag, indicating that the initial

300 mbrane acyltransferase enzyme PagP occurs in immunostimulatory Ypt and Ye strains, but not in immune-