ライフサイエンスコーパス: immunosurveillance

1 n the glial cells of the CNS and escape from immunosurveillance.

2 uggesting that it is a poor target for early immunosurveillance.

3 cells and eliminate them in a process termed immunosurveillance.

4 another defensive strategy for human cancer immunosurveillance.

5 OR is also critical in T cells implicated in immunosurveillance.

6 monstrating that M/D-driven tumors are under immunosurveillance.

7 autophagy is required for optimal anticancer immunosurveillance.

8 elping protect the infected tumor cells from immunosurveillance.

9 elf-tolerance, immune suppression, and tumor immunosurveillance.

10 serum IgMs interplay with ficolins in cancer immunosurveillance.

11 cells contribute to antitumor and antiviral immunosurveillance.

12 using chronic immune stimulation or impaired immunosurveillance.

13 nhibitory receptor Siglec-9, thereby evading immunosurveillance.

14 ducts are microbial signatures for MAIT-cell immunosurveillance.

15 PD-L1 expression to suppress T cell-mediated immunosurveillance.

16 umor cell growth and thus counteracts cancer immunosurveillance.

17 cells harnesses their natural role in tumor immunosurveillance.

18 es, employs a variety of mechanisms to evade immunosurveillance.

19 rochimerism may impart an allogeneic edge in immunosurveillance.

20 and the activation of host-dependent cancer immunosurveillance.

21 ng tumor cells with an escape mechanism from immunosurveillance.

22 astatic lesions and potential sites of tumor immunosurveillance.

23 vating receptor crucially involved in cancer immunosurveillance.

24 owth of some cancers, a process termed tumor immunosurveillance.

25 re critical for priming efficient anti-tumor immunosurveillance.

26 -privileged tissue niche with impaired tumor immunosurveillance.

27 d probably contributed independently to GIST immunosurveillance.

28 s making the fungus less susceptible to host immunosurveillance.

29 stent human pathogen in the face of constant immunosurveillance.

30 e broad significance of T(eff) for effective immunosurveillance.

31 iller (NK) cells are involved in trophoblast immunosurveillance.

32 delay M/D-driven oncogenesis by reactivating immunosurveillance.

33 llular immune response, thereby facilitating immunosurveillance.

34 maximize the sensitivity and speed of T-cell immunosurveillance.

35 helial apoptosis that would normally support immunosurveillance.

36 ereby implicating this NKG2D ligand in tumor immunosurveillance.

37 iting lead to a progressive escape from host immunosurveillance.

38 duce even more profound failure in long-term immunosurveillance.

39 ighly sophisticated strategies to evade host immunosurveillance.

40 ystemic immune suppression and inhibits host immunosurveillance.

41 to the tumor microenvironment, and providing immunosurveillance.

42 , the cell type thought to provide cutaneous immunosurveillance.

43 c development and growth in a process termed immunosurveillance.

44 osed to promote HRS survival and escape from immunosurveillance.

45 ether such T cells could contribute to tumor immunosurveillance.

46 kine receptors to metastasize and circumvent immunosurveillance.

47 to contribute to tumor development-blocking immunosurveillance.

48 to date for the biological relevance of ARF immunosurveillance.

49 crucial regulators of autoimmunity and tumor immunosurveillance.

50 controlling PI-9 levels and thereby blocking immunosurveillance.

51 with worse outcome, possibly from decreased immunosurveillance.

52 ingly rare, suggesting a failure of cellular immunosurveillance.

53 tegy involving both tumor cell depletion and immunosurveillance.

54 cells into cerebrospinal fluid supports CNS immunosurveillance.

55 and A to serve a similar function in cancer immunosurveillance.

56 unoevasion and in subverting T cell-mediated immunosurveillance.

57 ical control of the disease despite disabled immunosurveillance.

58 iver cancer to study oncogene cooperation in immunosurveillance.

59 ation can subvert therapy-induced anticancer immunosurveillance.

60 NK cells and plays a critical role in tumor immunosurveillance.

61 on that may serve as a means for cancer cell immunosurveillance.

62 nting tumor neovascularization and restoring immunosurveillance.

63 anifest have managed to subvert or hide from immunosurveillance.

64 afficking in peripheral nerves during normal immunosurveillance.

65 ve while exerting local noncytolytic hepatic immunosurveillance.

66 nvironmental and systemic processes, such as immunosurveillance.

67 ays robustly contribute to MHC class I-based immunosurveillance.

68 ligand 1 (PD-L1) to subvert T-cell-mediated immunosurveillance.

69 nd hence escape natural and therapy-elicited immunosurveillance.

70 by but not predominantly caused by a lack of immunosurveillance.

71 -like molecules in the context of intestinal immunosurveillance.

72 s-talk between IgE and T cell-mediated tumor immunosurveillance.

73 T lymphocytes and are key targets of cancer immunosurveillance.

74 ses in other tissues, possibly via defective immunosurveillance.

75 o coinfection and potentially reducing tumor immunosurveillance.

76 don-based translation initiation in pathogen immunosurveillance.

77 sed by the immune system in a process termed immunosurveillance.

78 ntrol of oncogenic viruses and reduced tumor immunosurveillance.

79 Thus, immunosurveillance activities by columnar epithelial cel

80 SC toward immune cells, thereby compromising immunosurveillance against cancer.

81 gammadelta T cells provide protective innate immunosurveillance against certain malignancies, particu

82 Compelling evidence for naturally occurring immunosurveillance against malignancies informs and just

83 potential to be used clinically to reinstate immunosurveillance against MHC class I-deficient tumors.

84 adelta T cells can indeed provide protective immunosurveillance against spontaneously arising mouse p

85 NK cells play important roles during immunosurveillance against tumors and viruses as they tr

86 nd NK cells and, hence, may be essential for immunosurveillance against tumors and/or viruses that ev

87 rammed cell death 1 promotes T-cell-mediated immunosurveillance against tumours, and has been associa

88 Cancer cells develop mechanisms to escape immunosurveillance, among which modulating the expressio

89 id tissues and sites of infection, providing immunosurveillance and a first line of defense against i

90 that phenotypically divergent DCs drive both immunosurveillance and accelerated malignant growth.

91 of IFN-gamma that promotes successful tumor immunosurveillance and antimicrobial immunity.

92 l, noninflamed skin that most likely conduct immunosurveillance and are implicated in the development

93 Human TRAIL-R1 and R2 play a role in immunosurveillance and are targets for cancer therapy, b

94 ors, as well as extracellular roles in tumor immunosurveillance and autoimmunity.

95 evidence for a novel exosome-mediated innate immunosurveillance and defense mechanism of the human up

96 tumor sites during therapy, and aid in tumor immunosurveillance and destruction.

97 ntigen (pHLA) complexes and is essential for immunosurveillance and disease control.

98 mportant to understand the interplay between immunosurveillance and disease transformation, but also

99 e mechanisms underlying NKG2D-mediated tumor immunosurveillance and escape.

100 inflammatory lesions and have been linked to immunosurveillance and graft rejection.

101 r understanding of tissue immunogenicity and immunosurveillance and guide intensifying clinical inter

102 neck cancer, including the concept of cancer immunosurveillance and immune escape.

103 The protective role of NKT cells in tumor immunosurveillance and immunity has been well documented

104 derstanding the mechanisms leading to cancer immunosurveillance and immunoediting.

105 mechanisms underlying the concepts of tumor immunosurveillance and immunoevasion has opened new oppo

106 /S1P axis in maintaining the balance between immunosurveillance and immunopathology and suggest that

107 ique insight into the early phases of tissue immunosurveillance and indicate that acute changes in NK

108 vivo evidence that CD226 is important for MM immunosurveillance and indicate that specific immune com

109 ure suggests that malignant HRS cells escape immunosurveillance and interact with immune cells in the

110 Thus, PMo contribute to cancer immunosurveillance and may be targets for cancer immunot

111 cating that NK cells alone can conduct tumor immunosurveillance and mediate protection.

112 A link between host immunosurveillance and neoplastic progression is reveale

113 hrough which WNT signaling influences cancer immunosurveillance and present potential therapeutic ave

114 unique features that confer enhanced cancer immunosurveillance and prevent the age-associated declin

115 e that this effect of FLT3-ITD might subvert immunosurveillance and promote leukemogenesis in a cell-

116 eas early initiation of HAART should improve immunosurveillance and reduce the incidence of LMP1-posi

117 ancers in mice, thereby improving anticancer immunosurveillance and reducing tumor mass.

118 tumor cells is important for efficient host immunosurveillance and response to apoptotic stimuli.

119 uggesting therapeutic approaches to reviving immunosurveillance and sensitivity to immunotherapies.

120 h the tumor and blood that leads to impaired immunosurveillance and suboptimal efficacy of immunother

121 une sensor, NOD2, limited CTX-induced cancer immunosurveillance and the bioactivity of these microbes

122 at PTPN2 deletion in T cells enhances cancer immunosurveillance and the efficacy of adoptively transf

123 ng support for the physiologic role of tumor immunosurveillance and the increasing success of strateg

124 through the induction of MDSC, which inhibit immunosurveillance and thereby allow the unchecked persi

125 mplement system plays a key role in pathogen immunosurveillance and tissue homeostasis.

126 T cells play an important role in cancer immunosurveillance and tumor destruction.

127 aturation is an important correlate of tumor immunosurveillance and vaccine efficacy, we sought to de

128 d cells that play a major role in both tumor immunosurveillance and viral clearance via their effecto

129 nctional maturation to potentiate both tumor immunosurveillance and viral clearance.

130 modelers', is able to normalize the impaired immunosurveillance and/or trigger antitumor immune respo

131 considered important for cancer prevention, immunosurveillance, and control of cancer progression.

132 -associated carcinogenesis, models of cancer immunosurveillance, and immunotherapeutic strategies.

133 +) T cells play important functions in tumor immunosurveillance, and in certain cases they can direct

134 premetastatic lung environment, improve host immunosurveillance, and inhibit tumor metastasis.

135 on of tumorigenesis, protection by providing immunosurveillance, and participation in tissue repair.

136 are critical regulators of skin homeostasis, immunosurveillance, and the induction of T and B cell-me

137 r acquisition by tumors may cause failure of immunosurveillance, and their alteration in normal tissu

138 vant bacterial species are involved in tumor immunosurveillance, and their mechanism of action are un

139 The role of pfp-mediated immunosurveillance appeared to be of even more dramatic

140 Thus, tumor angiogenesis and escape of immunosurveillance are two cancer hallmarks that are tig

141 , ILC1 contribute an essential role in viral immunosurveillance at sites of initial infection in resp

142 hat in order to understand the complexity of immunosurveillance at the cell-cell junction, quantitati

143 ne candidates with properties to exert local immunosurveillance at the mucosal surfaces.

144 ic areas have diminished EBV-specific T cell immunosurveillance between the ages of 5 and 9 years, wh

145 plexus epithelium which regulates lymphocyte immunosurveillance between the blood and cerebrospinal f

146 NK) cells have important functions in cancer immunosurveillance, BM allograft rejection, fighting inf

147 l that B7-H6 is not only implicated in tumor immunosurveillance but also participates in the inflamma

148 tial for control of infections and for tumor immunosurveillance, but it can also drive pathological i

149 cting disseminating tumor cells from NK cell immunosurveillance, but the underlying mechanisms are no

150 -cell receptors perform an important role in immunosurveillance by binding to HLA-E complexes that ex

151 t that CD47 blockade directly enhances tumor immunosurveillance by CD8(+) T cells.

152 pose that most of these events affect cancer immunosurveillance by changing the balance between an ef

153 hology to evaluate the role of pfp-dependent immunosurveillance by comparing tumor progression in rat

154 Immunosurveillance by cytotoxic T cells requires that ce

155 tides from endogenous and viral proteins for immunosurveillance by cytotoxic T lymphocytes (CTL).

156 ed cytokines may therefore lead to defective immunosurveillance by memory T cells.

157 In parallel, radiation can impact immunosurveillance by modulating neoantigen expression.

158 L40 polymorphisms may aid evasion of NK cell immunosurveillance by modulating the affinity of the int

159 igand ULBP2 from their cell surface to evade immunosurveillance by NK cells and CD8 T cells.

160 hts provide an access point to restore tumor immunosurveillance by NK cells and to increase the effic

161 Self-MHC-I immunosurveillance by NK cells in NKC(KD) mice can be re

162 ds to loss of MHC-I-dependent "missing-self" immunosurveillance by NK cells.

163 findings raise the possibility of modulating immunosurveillance by pharmaceutical targeting ribosomes

164 We recently showed that immunosurveillance by pre-existing CD44(high)CD62L(low)

165 a suggest that established tumors may escape immunosurveillance by preventing clonal expansion of tum

166 DCs may provide insight into the evasion of immunosurveillance by SCC.

167 It is thought that tumor cells evade immunosurveillance by shedding membrane ligands that bin

168 oting inflammatory changes or variability in immunosurveillance by the adaptive immune system but res

169 Although cancer cells can escape immunosurveillance by tuning down autophagy, certain che

170 inducer Snail and the metastasis suppressor/immunosurveillance cancer gene product Raf-1 kinase inhi

171 Microglia are dynamic immunosurveillance cells in the CNS.

172 During natural killer (NK) cell immunosurveillance, clustering and transfer of receptor

173 Careful immunosurveillance conducted as part of ongoing clinical

174 Immunosurveillance constitutes the first step of cancer

175 whether strain-specific variability in tumor immunosurveillance contributes to differences in lung ca

176 ated apoptosis-inducing ligand (TRAIL) is an immunosurveillance cytokine that kills cancer cells but

177 refore reveal unique potential as artificial immunosurveillance devices.

178 , immunogenic epitopes in expanding relevant immunosurveillance effectors to block tumor formation, r

179 ibosomal products to contribute peptides for immunosurveillance, enabling quantitation of peptide gen

180 r role in oncogenesis by both impairement of immunosurveillance, enhancement of chronic viral infecti

181 tivation of PPARgamma/RXRalpha and result in immunosurveillance escape by inhibiting CD8+ T-cell recr

182 2(1-8) provides a clear demonstration of how immunosurveillance exploits natural errors in protein tr

183 Cancer immunosurveillance failure is largely attributed to insu

184 in the natural killer gene complex (NKC) in immunosurveillance for carcinogen-induced lung cancer.

185 ting the immune response to viral infection, immunosurveillance for malignant cells, and liver regene

186 little is known about the role of T cells in immunosurveillance for mtDNA aberrations.

187 eta T cells, B cells, and NK cells, allowing immunosurveillance for signatures of "altered self" on t

188 are often exploited by tumour cells to evade immunosurveillance have emerging roles in modulating the

189 errant WNT signaling may also subvert cancer immunosurveillance, hence promoting immunoevasion and re

190 The tumor immunosurveillance hypothesis describes a process by whi

191 that retroviral genes contribute to tumoral immunosurveillance in a process that can be generally bo

192 ffects of TAM, raloxifene and ICI 182,780 on immunosurveillance in breast cancer.

193 ent potential targets for manipulating MHC-I immunosurveillance in cancers, infectious diseases, and

194 was to characterize the physiology of tumor immunosurveillance in children with high-risk neuroblast

195 HIV(+) individuals may influence NK-mediated immunosurveillance in patients receiving cART.

196 indings that are in support of tumor-induced immunosurveillance in regulating metastatic spread, incl

197 hat EBV latency proteins are under increased immunosurveillance in the post-combined antiretroviral t

198 st that IR exposure may result in diminished immunosurveillance in the skin, which could render the h

199 n of MARCO, leading to compromised bacterial immunosurveillance in vivo.

200 he post septic immune system obstructs tumor immunosurveillance, in part, by augmented Treg expansion

201 endently or in sequence: elimination (cancer immunosurveillance, in which immunity functions as an ex

202 an essential requirement for tumors to evade immunosurveillance independent of TGF-beta produced by t

203 Tumor immunosurveillance influences oncogenesis and tumor grow

204 ns controversial whether clinical failure of immunosurveillance is a result of lymphocyte dysfunction

205 Tumor immunosurveillance is a well-established mechanism for r

206 entiated tumor, indicating that pfp-mediated immunosurveillance is able not only to delay the growth

207 CD8(+) T cell immunosurveillance is based on recognizing oligopeptides

208 that an early "elimination phase" of cancer immunosurveillance is eventually overwhelmed by a growin

209 Escape from immunosurveillance is increasingly recognized as a landm

210 preneoplastic skin cells, demonstrating that immunosurveillance is normally induced but may be ineffe

211 n disease especially favored by insufficient immunosurveillance, late PTLD often resembles tumors wit

212 Accumulating evidence suggests that immunosurveillance may also be critical for regulating m

213 own previously that the suppression of tumor immunosurveillance may be a mechanism by which tumors re

214 Evasion of NK immunosurveillance may have importance for MDS disease p

215 Importantly, this is also a natural immunosurveillance mechanism against cancer development.

216 fungi, but C. neoformans can circumvent this immunosurveillance mechanism by instead exposing chitosa

217 These findings reveal a tumor-elicited immunosurveillance mechanism that engages unconventional

218 targeting multiple immune evasion as well as immunosurveillance mechanisms for the generation of a pr

219 tably begins to elucidate the impact of host immunosurveillance mechanisms in response to the normal

220 l tissues is affected by innate and adaptive immunosurveillance mechanisms in response to the normal

221 (SPF) mice have revealed the impact of host immunosurveillance mechanisms in response to the normal

222 ediated cytotoxicity is one of the principal immunosurveillance mechanisms involved in the fight agai

223 ard genetic screen designed to examine tumor immunosurveillance mechanisms.

224 However, to what extent immunosurveillance occurs in spontaneous cancers and the

225 f RANK-RANKL interaction in NK cell-mediated immunosurveillance of acute myeloid leukemia (AML).

226 antigen presentation makes perfect sense for immunosurveillance of acute virus infections, in which s

227 Siglec-E-deficient mice also showed enhanced immunosurveillance of autologous tumors.

228 dy the role of CD70 reverse signaling in the immunosurveillance of B-cell malignancies in vivo.

229 ERT-specific T cells could contribute to the immunosurveillance of breast cancer and suggest novel op

230 I antigen presentation system enables T cell immunosurveillance of cancers and viruses.

231 An efficient immunosurveillance of CD8(+) T cells in the periphery de

232 unity to cyclin B1 might be important in the immunosurveillance of cyclin B1+ tumors.

233 for NK cell development but was critical for immunosurveillance of epithelial and lymphoid malignanci

234 These results implicate macrophages in the immunosurveillance of hematopoietic cells and leukemias.

235 HSV-specific CD8(+) T cells provide constant immunosurveillance of HSV-1 latently infected neurons in

236 R) NKp30 (CD337) is a key player for NK cell immunosurveillance of infections and cancer.

237 hreshold levels may be sufficient to restore immunosurveillance of mesenchymal-like cancer cells that

238 ells and therefore have implications for the immunosurveillance of mitochondrial aberrations in cance

239 We found that macrophages participate in the immunosurveillance of myocardial tissue.

240 C class I presentation pathway, allowing for immunosurveillance of newly synthesized proteins by cyto

241 tural killer T (NKT) cells in the biology of immunosurveillance of osteosarcoma.

242 ng a model in which NK cells are involved in immunosurveillance of pediatric B-ALL via interaction of

243 ic pathways necessary for the metabolism and immunosurveillance of prematurely terminated polypeptide

244 We propose that effective immunosurveillance of senescent cells in salamanders sup

245 65, an activating receptor implicated in the immunosurveillance of skin, bound to its NKC-encoded lig

246 nd are thought to allow for NK cell-mediated immunosurveillance of stressed or infected tissues.

247 erapies could well interfere with protective immunosurveillance of the central nervous system.

248 pe 1 (HSV-1)-specific CD8(+) T cells provide immunosurveillance of trigeminal ganglion (TG) neurons t

249 Immunosurveillance of tumor cells depends on NKp30, a ma

250 ort peptides enables CD8(+) T cell (T(CD8+)) immunosurveillance of tumors and intracellular pathogens

251 class I antigen processing pathway, linking immunosurveillance of viruses and tumors to mechanisms o

252 s I molecules, enable CD8(+) T cell mediated immunosurveillance of viruses, other intracellular patho

253 ion is expected to play an important role in immunosurveillance or immunosuppression mediated by vari

254 etic and bioenergetic demands while escaping immunosurveillance or therapeutic interventions.

255 esults in either tumor destruction by way of immunosurveillance or tumor outgrowth.

256 with overlapping mutations at every step of immunosurveillance, particularly self-antigen presentati

257 n the cytosol of mammalian cells via a novel immunosurveillance pathway.

258 sol, L. pneumophila also activates cytosolic immunosurveillance pathways, thereby triggering robust p

259 and resident subsets, ostensibly defined by immunosurveillance patterns but in practice identified b

260 hocytes that play an important role in tumor immunosurveillance, preferentially eliminating targets w

261 An occupational immunosurveillance program (OISP) has been implemented t

262 nhibitory strategies that may reactivate the immunosurveillance program.

263 lationships: these are chronic inflammation, immunosurveillance, prophylaxis, and we propose adding a

264 compatibility complex class I-mediated tumor immunosurveillance provides mechanistic insights into ho

265 nstrate that cocaine also interacts with the immunosurveillance receptor complex, Toll-like receptor

266 NKG2D is an important immunosurveillance receptor that responds to stress-indu

267 Cancer immunosurveillance relies on effector/memory tumor-infil

268 The dynamics of cancer immunosurveillance remain incompletely understood, hampe

269 Myeloma immunosurveillance remains incompletely understood.

270 nds may alone initiate a rapid, multifaceted immunosurveillance response in vivo.

271 extent to which memory CD4(+) T cells share immunosurveillance strategies with CD8(+) resident memor

272 ls employ mechanisms to evade NKG2D-mediated immunosurveillance, such as NKG2D ligand (NKG2DL) sheddi

273 lications for the development of a synthetic immunosurveillance system (SIS).

274 y, an essential component of the host cancer immunosurveillance system, STAT1 is also overexpressed i

275 g as a critical component of the host cancer immunosurveillance system.

276 ue microenvironments with finely tuned local immunosurveillance systems, many of which are in close a

277 tant and previously unappreciated element of immunosurveillance that needs to be taken into account i

278 nical implications, implicitly linked to the immunosurveillance theory.

279 peptide presentation to evade CD8(+) T cell immunosurveillance, though how this is accomplished is n

280 eristics of tumors is their ability to evade immunosurveillance through altering the properties and f

281 e, terminally differentiated subsets mediate immunosurveillance through diverse peripheral sites.

282 arcoma model and that NKT cells can regulate immunosurveillance through more than one pathway.

283 ome cancer treatments can restore anticancer immunosurveillance through the induction of tumor immuno

284 ibitor (SPI) in the escape of MSCs from host immunosurveillance through the inhibition of granzyme B

285 ogy, ranging from trafficking leukocytes and immunosurveillance to the regulation of metabolism and n

286 l for competent immunization-mediated cancer immunosurveillance, unmanipulated CD4 T cell responses t

287 xia in solid tumors contributes to decreased immunosurveillance via down-regulation of Kv1.3 channels

288 Thus, the dualistic role of immunosurveillance vs. inflammation in modulating tumor

289 her the immune responses that mediate cancer immunosurveillance vs. those responsible for inflammator

290 KT-deficient mice, suggesting that antitumor immunosurveillance was inhibited by CD11b(+)Gr1(+) cells

291 ore a direct role of endogenous IgE in tumor immunosurveillance was investigated.

292 These early concepts about cancer immunosurveillance were further developed in the decades

293 stimulation of type II NKT cells suppressed immunosurveillance, whereas stimulation of type I NKT ce

294 highlights a novel function for A20 in local immunosurveillance, which added to its vasculoprotective

295 scent tumor cells in a process termed cancer immunosurveillance, which functions as an important defe

296 g an atypical, myeloid-biased mode of innate immunosurveillance, which may contribute to its remarkab

297 as prompted the immunoribosome hypothesis of immunosurveillance, which posits that MHC class I peptid

298 biting early stages of tumor growth, through immunosurveillance while facilitating later stages of tu

299 n "one protein, one peptide" representation, immunosurveillance would be heavily biased toward the mo

300 a unique role for CD57(+) NK cells in cancer immunosurveillance, yet there is scant information about