ライフサイエンスコーパス: impair

1 th cell types, but spread in fibroblasts was impaired.

2 rly B-cell development in the bone marrow is impaired.

3 AD mice, SWR-DW and spindle-DW coupling were impaired.

4 n cells, and cause neurological disease when impaired.

5 smic domain/transport-dependent targeting is impaired.

6 Mental switching performance was impaired 7% (IQR = 0-19) after indomethacin (P = 0.04),

7 and degradation of phosphorylated SMAD3 and impaired a SMAD3/beta2SP-dependent tumor-suppressing pat

8 ESCs have a slower self-renewal rate and an impaired ability to differentiate towards cardiac mesode

9 c reticular nucleus neurons, burst firing is impaired accompanied by attenuated IT.

10 but not in B3GLCT (-/-) cells suggested that impaired ADAMTSL2 secretion is not responsible for skele

11 caused by loss of O-fucosylation on TSR3 and impaired ADAMTSL2 secretion.

12 disease, with a connection between aging and impaired adaptive immune responses to SARS-CoV-2.

13 e show that persistent antigenic stimulation impaired ADP-coupled oxidative phosphorylation.

14 Two monkeys were impaired after 0.1 mg/kg olanzapine and two were impaire

15 ired after 0.1 mg/kg olanzapine and two were impaired after 0.3 mg/kg deschloroclozapine.

16 egulatory protein AKAP150 at cysteine 36, to impair AKAP150-TRPV4 channel signaling at myoendothelial

17 roliferation of resident epithelial cells is impaired, alternative regeneration mechanisms can occur.

18 ar-stage hyperoxia injury contributes to the impaired alveolarization and septal thickening observed

19 s involved in lung development along with an impaired alveolarization in female prenatally stressed m

20 re-conditioning (PreCon) is decreased due to impaired AMP-activated protein kinase (AMPK) signaling.

21 oor cell viability or RNA quality, which may impair analysis of effector activities of these cells.

22 IFN-mediated JAK-STAT signaling is severely impaired, and activation of MAPKs and PI3K signaling pat

23 gly, NK cell recruitment and activation were impaired, and metastatic burden was increased in E2 (-/-

24 derstanding the processes underlying normal, impaired, and recovered language performance has been a

25 Impaired angiogenesis in the wound tissues results in de

26 t CD40L-overexpressing CAR T cells elicit an impaired antitumor response in the absence of cDC1s.

27 CD8+ T cell response to vaccination is impaired as a result of cDC1 dysregulation.

28 Impairing astrocytic delivery of energy substrates by re

29 TBC1D15-NuMA1 association impaired asymmetric division machinery by hijacking NuMA

30 impairment at baseline and 2 (22%) remained impaired at week 24.

31 duced expression of Ucp1 and Pgc-1alpha with impaired ATF2 genomic binding.

32 c silencing of USV-responsive neurons in TeA impairs auditory-driven maternal preference in a pup-ret

33 inding to its negative regulator BCL2, which impairs autophagy flux.

34 Oligodendrocyte signatures suggested impaired axonal myelination and metabolic adaptation to

35 d by more severe intestinal inflammation and impaired bacterial clearance.

36 of structural integrity of the cuticle, and impaired barrier function.

37 livery systems which have potential to cross impaired BBB, target and deliver drugs selectively to ac

38 lipid-raft-associated surface receptors, and impaired BCR signalling and cellular adhesion.

39 1) increases absolute insulin secretion but impairs beta-cell function, 2) causes insulin resistance

40 lly occurring after CRS and characterized by impaired blood-brain barrier integrity.

41 as cerebral amyloid angiopathy (CAA), which impairs blood-brain barrier (BBB) function and accelerat

42 ant overlap with the patterns of empirically impaired brain regions on later scans, at both group and

43 secretion under control conditions were less impaired by atorvastatin than preparations that were non

44 In contrast, reversal learning was impaired by D2R antagonism, but not D1R antagonism, in t

45 Importantly, connectivity is impaired by insults, which mimic the diabetic milieu, in

46 r is sufficient to recover salivary function impaired by irradiation.

47 d in both species, only Z. marina growth was impaired by the accumulative heat stress imposed by the

48 e guide RNA (sgRNA)-guided and catalytically impaired Campylobacter jejuni CRISPR-associated protein

49 ur hypothesis, patients with HFpEF displayed impaired cardiac beta-receptor sensitivity compared with

50 n are vulnerable to vitamin D deficiency and impaired cardiovascular health; vitamin D replenishment

51 Recipients of an HLA-DR1 donor also have an impaired cardiovascular outcome.

52 at a mutation at the C terminus of eIF2gamma impairs CDC123 promotion of eIF2 complex formation and d

53 This, in turn, impairs CEBPB's association with its Cebpa promoter-prox

54 A2, result in sphingolipid abnormalities and impaired cell growth that are corrected by treatment wit

55 functional exhaustion) is not upregulated on impaired cells but instead is upregulated on highly func

56 We show that beta-HPV E6 more broadly impairs cellular signaling, indicating that the viral pr

57 acid levels (a marker of LXR activation) and impaired chemotactic response toward CXCL8 compared with

58 hils and white blood cells showed a severely impaired chemotactic response.

59 y with autosomal recessive inheritance) that impair ciliary beating cause a variety of motile ciliopa

60 duction of this vasomotion may contribute to impaired clearance of Abeta.

61 stolic and diastolic cardiac dysfunction and impaired clinical outcomes in patients with nonischemic

62 ignatures were associated with predominantly impaired clinical state- and trait-level phenotypes, whi

63 nglia tissue iron levels have been linked to impaired cognition in iron deficient children and adults

64 EMENT Repeated exposure to stress profoundly impairs cognitive functions like memory, attention, or d

65 works in pediatric OCD may contribute to the impaired control over intrusive thoughts early in the il

66 g treadmill running in rats due, in part, to impaired convective and diffusive O(2) delivery, and thu

67 ity and enhanced transmission may arise from impaired cyclic nucleotide signalling, resulting from co

68 T cells and NK cells exhibited impaired cytolytic activity, and mice infected with mous

69 An impaired decline in blood pressure at rest is typical in

70 The finding that PTPN14 binding by HPV E7 impairs differentiation has significant implications for

71 histone trimethylation at meiotic hotspots, impaired DNA double-strand-break repair, and reduced cro

72 Co-depletion of Mdm4 and Mdm2 further impaired DNA replication, and the overexpression of each

73 Visual perception was the most impaired domain, while scholastic progression was age-ap

74 atial function domains were the most serious impaired domains in the major cognitive impairment group

75 Memory and language were the most severe impaired domains in the mild cognitive impairment group,

76 ogenesis and cilia function is significantly impaired during differentiation of CRSwNP epithelium due

77 and developed in vivo prior to transfer can impair early placentation and fetal growth, but this eff

78 ular matrix (ECM) and that its loss leads to impaired ECM engulfment and a concomitant accumulation o

79 ide in noncoding regions; this knowledge gap impairs efforts to understand the molecular mechanisms o

80 stenosis undergoing TAVR, even with baseline impaired eGFR, CKD stage is more likely to stay the same

81 Contractile function was similarly impaired (ejection fraction, day 2: 40.9% +/- 9.7% vs. 5

82 n an inefficient and senescent placenta that impairs embryonic development.

83 umulate within Sac1(ts) retinal cells due to impaired endo-lysosomal degradation.

84 One mechanistic hypothesis involves impaired endothelium-dependent vasodilation through reac

85 novel therapeutic approaches to restore the impaired epithelial repair mechanisms in COPD, which is

86 naling pathways in MDSs causes anemia due to impaired erythroid maturation.

87 out among the mechanisms contributing to the impaired erythropoiesis in the setting of reduced kidney

88 The EP group had significantly impaired exercise capacity.

89 we further demonstrate that proximal threats impaired extinction efficacy via persistent multivariate

90 bulo-ocular reflex (VOR) gain adaptation but impaired eyeblink conditioning (EBC), which relies on th

91 terized by fear overgeneralization involving impaired fear regulation by safety signals.

92 etes can lead to pregnancy complications and impaired fetal development.

93 role of CT-1 in fasting is confirmed by the impaired food restriction-induced adipose tissue lipid m

94 nes in patients with HLHS, which may portend impaired functional reserve of the single-ventricle circ

95 developmental disorders are characterized by impaired functional synaptic plasticity and abnormal den

96 we hypothesized that hepatic steatosis might impair glucagon's action on hepatic amino acid metabolis

97 Exposure to PM2.5 impaired glucose and insulin tolerance and reduced energ

98 lpha protein instability was associated with impaired glucose metabolism and lower glycolytic enzyme

99 nism as to how TIH, prevalent in people with impaired glucose metabolism, contributes to cardiovascul

100 Mice lacking TrkB.T1 show impaired glucose tolerance and insulin secretion.

101 oping gestational diabetes mellitus and have impaired glucose tolerance whilst cholestatic.

102 inhibition via an anti-alpha-klotho antibody impaired glucose tolerance.

103 rodent schizophrenia model characterized by impaired glutathione synthesis, the Gclm knockout mouse,

104 Human studies have implicated impaired glymphatic function in both AD and iNPH.

105 ty in the causation of addiction, related to impaired goal-directed actions, as well as countervailin

106 ureus biofilm infection in wounds results in impaired granulation tissue collagen leading to compromi

107 marine diatom species release oxylipins that impair grazer reproduction and serve as signaling molecu

108 In the cognitively impaired group, younger age (P = 0.02), higher baseline

109 e show that mutant strains lacking gigC have impaired growth in the absence of the amino acid cystein

110 viability, and immunoblotting revealed that impaired growth is due to perturbation of cell cycle pro

111 ransporters, all of which are precursors for impaired gut integrity and performance.

112 ocked plaque remodeling and contraction, and impaired hallmarks of inflammation resolution, including

113 y, defined as any atrial dysfunction causing impaired heart performance, symptoms, and worsening qual

114 en storage disease type-Ia (GSD-Ia) leads to impaired hepatic autophagy, a recycling process importan

115 shortening, progressive telomere dysfunction impaired hepatic endoderm formation.

116 ory performance in a scene recognition task, impaired hippocampal connectivity to multiple prefrontal

117 The discovery of impaired hippocampal synaptic plasticity in the heterozy

118 n attenuated non-histaminergic itch, without impairing histamine-induced itch.

119 Patients with PTLDS reported impaired HRQoL compared to the general US population.

120 uch paradoxical findings may be explained by impaired hypoxic pulmonary vasoconstriction in infected

121 d fewer risk factors, but these cells showed impaired IFN-gamma production.

122 Impaired IL-17A and IL-22 production correlated with red

123 presses LPS-induced macrophage activation by impairing IL-1beta production.

124 LRG1 deletion causes impaired immune cell infiltration, reepithelialization,

125 those receiving combination therapy, have an impaired immune response compared to controls.

126 deletion of Dot1L in T cells resulted in an impaired immune response.

127 immune checkpoint inhibitors, an immature or impaired immune system and inhibitory tumor microenviron

128 ociated with neuropathology in patients with impaired immunity and/or inflammatory diseases.

129 sponses during allergic inflammation, but is impaired in asthma.

130 ction of the Ep group were detected slightly impaired in comparison with the control group (P >0.05);

131 tory T cells (Tregs), which are functionally impaired in DED, remains unclear.

132 or cells (HSPC) from the bone marrow (BM) is impaired in diabetes.

133 uals, the resolution phase was substantially impaired in elderly individuals.

134 sts that newborn monocytes are intrinsically impaired in extravasation through quiescent endothelia,

135 n and fatty acid and glucose metabolism were impaired in HF-patients compared with HC (P<0.05).

136 The GLP-1 system is known to be impaired in insulin-resistant conditions, and we sought

137 lX DeltapgnE double mutant was substantially impaired in its ability to form Pel-dependent biofilms.

138 They were also modestly impaired in one simpler spatial task, finding a visible

139 contrast, automatic inhibition was abnormal/impaired in patients with tic disorders.

140 In summary, proNGF maturation is impaired in preclinical and clinical AD while mature NGF

141 Wound-healing was also impaired in PSW compared to controls at baseline and fol

142 on errors benefits learning in health and is impaired in psychosis.

143 receiving cue illumination were specifically impaired in rapid uncertainty-safety discrimination.

144 Modulation of activity duration is impaired in rLG, confirming the role of reflex feedback

145 Moreover, interoceptive performance was impaired in the HHD group.

146 s of spontaneous pain and were significantly impaired in the rule-shifting task while genetic and pha

147 ynaptic plasticity, learning, and memory are impaired in these mutant mice.

148 ion of AP factors, or AH50 less than median, impaired in vitro serum control of KP that was restored

149 technical-reasoning hypothesis, cognitively-impaired individuals will lack the cognitive ability to

150 from healthy volunteers, demonstrating that impaired innate immune mechanisms following DEP exposure

151 (95% CI, 1.4-4.8), and 3.2 times the odds of impaired instrumental activities of daily living (95% CI

152 nstrated improved glucose tolerance, despite impaired insulin sensitivity and enhanced pyruvate-media

153 t wheat and rye DL stabilized A-W interfaces impair interactions between its proteins, as reflected b

154 Here, we found that ROS impaired interferon response during murine herpesvirus i

155 These defects were a consequence of impaired IP3R function in combination with defective STI

156 entry, replication, and spread as well as to impair its lethal effects.

157 a truncated form of the FKBP8 protein, thus impairing its interaction with BCL2 and ultimately leadi

158 Removing Syt1 or impairing its release inhibitory function (Syt1(9Pro)) i

159 ith DDB1-DDB2 and promotes DDB2 stability by impairing its ubiquitination independent of methyltransf

160 nd flow cytometry showed that F302L does not impair KCNA2 subunit surface trafficking.

161 0) = 1.972, p = 0.049), it was outweighed by impaired landmark-based navigation (t(980) = 6.374, p <

162 rmalities such as psychomotor hyperactivity, impaired learning and memory in the recipient animals.

163 siological features, and its contribution to impaired linear and ponderal growth has been hampered by

164 ses with high accuracy in both older hearing-impaired listeners and age-matched normal-hearing contro

165 lated endothelial dysfunction, which further impairs local microcirculation with a feed-forward loop

166 Kir6.1 or SUR2 subunits results in severely impaired lymphatic contractile responses to pinacidil.

167 suppress host defense mechanisms, including impairing macrophage phagocytosis.

168 een reduced transport of synaptic cargos and impaired maintenance of synaptic transmission and plasti

169 arizes the bacterial membrane potential, and impairs membrane recovery.

170 Thus, we hypothesized that impaired memory consolidation mechanisms in hippocampal-

171 without affecting existing oligodendrocytes impaired memory consolidation of water maze, as well as

172 tion markedly improved hepatic inflammation, impaired microcirculation, and fibrosis.

173 Impaired microvascular perfusion is central to the devel

174 Our data suggest that the C9orf72-HRE impairs Mitf/TFEB nuclear import, thereby disrupting aut

175 Our work raises the hypothesis that impaired mitochondrial calcium transport contributes to

176 aintenance of ATP levels under conditions of impaired mitochondrial respiration.

177 and show that elevated non-vacuolar cysteine impairs mitochondrial respiration by limiting intracellu

178 e 10 mg dose of the GABA(B) agonist baclofen impaired motor sequence learning and visuomotor learning

179 h exogenous mtDNA is lost from metabolically impaired, mtDNA-intact (rho+) cells.

180 C (Villin-Cre(ERT2); Dsc2 (fl/fl)) exhibited impaired mucosal repair after biopsy-induced colonic wou

181 le fiber atrophy, sarcolemmal fragility, and impaired muscle regeneration.

182 In myoblasts, we find that impaired NADH oxidation upon electron transport chain (E

183 Finally, interfering with abscission impairs naive pluripotency exit, and artificially induci

184 Disrupting each cluster selectively impairs native Ded1 association with eIF4A or eIF4E, and

185 Concordantly, rs679482-A impairs native repressor activity and increases basal an

186 ance, and inhibiting eye movements in humans impaired navigation precision.

187 us, by altering the stringency and partially impairing negative selection, the host generates new vir

188 ive diseases (NDDs) comprise conditions with impaired neuronal function and loss and may be associate

189 CLCb had a reduced synaptic vesicle pool and impaired neurotransmission compared to WT mice, while nC

190 eolae in aECs, but not in neighbouring SMCs, impaired neurovascular coupling.

191 Studies have shown impaired neurovascular function in several mouse models

192 mutations of individual genes that result in impaired neutrophil number or function, and provide insi

193 its C-terminal cytoplasmic regulatory domain impair NHE6 activity and endosomal function are poorly u

194 l maintenance complex member 10 (MCM10) that impaired NK cell maturation in a child with fatal suscep

195 We observed low NK cell numbers and impaired NK cell maturation, suggesting that STAT5b is i

196 activation, perineural net degradation, and impaired NMDA receptor function.

197 ectivity in cultured neurons or in vivo, but impaired NMDA-receptor-mediated responses.

198 niche, and a molecular mechanism whereby AML impairs normal hematopoiesis by remodeling the mesenchym

199 Stress did impair novel object recognition in both sexes and social

200 PO(2) during twitch contractions reflecting impaired O(2) delivery-to-utilization matching.

201 rtex (lateral occipital complex) selectively impaired object recognition, while TMS over scene-select

202 arring response that stiffens the tissue and impairs ocular function.

203 ts implicated in the selection of movements, impaired operation of GABA signaling within the striatum

204 Ser/Thr kinase (BRAF), that result in kinase-impaired or kinase-dead BRAF have the highest mutation f

205 impact these cascades, in particular through impaired organellar interfacing, to propose 'subcellular

206 Impaired oxygen and cellular metabolism is a hallmark of

207 age abilities map to the brain in normal and impaired participants, including the diverse, graded var

208 phate activities are chain-length dependent, impair pathogen clearance, antagonize phagocyte recruitm

209 ITGAV expression is correlated with an impaired patient outcome in the group of patients withou

210 lighted by the pathological consequences and impaired performance resulting from aberrant network exc

211 medicated patients with schizophrenia showed impaired performance.

212 etween-meal cognitive differences, uniformly impairing performance.

213 on of the insular cortex using GABA agonists impairs performance of the task.

214 s modulates host defense mechanisms, notably impairs phagocytosis, and increases TB drug metabolism.

215 Furthermore, attenuated cGMP signals led to impaired phosphodiesterase two dependent negative cGMP-t

216 nide has antiarrhythmic effects on AF due to impaired Pitx2 by preventing spontaneous calcium release

217 m sporogonic and blood stage development and impairs Plasmodium berghei development inside hepatocyte

218 estingly, PEL-negative individuals showed an impaired platelet aggregation, confirming a role for ABC

219 a and liver kinase B1 but fails to normalize impaired PPAR-alpha expression or metabolic abnormalitie

220 osphorylated tau expression, correlated with impaired preoperative executive function.

221 ondrial redox potential and/or ATP synthesis impaired proline biosynthesis.

222 Furthermore, inhibiting these neurons impairs punishment-based learning without affecting rewa

223 of overexpressing efflux pumps are similar (impaired QS response), the underlying mechanisms are dif

224 eading to significant health care burden and impaired quality of life.

225 y had a functional defect in HR, assessed by impaired RAD51 foci formation on end of treatment biopsy

226 a global change in immunological profile and impaired recruitment and activation of T cells.

227 Moreover, c3a.1(-/-) zebrafish larvae have impaired recruitment to localized bacterial infections a

228 onments that impact stem cell plasticity and impair regenerative capacity.

229 s of Notch1 intracellular domain (N1ICD) and impaired regenerative response to injury in comparison t

230 e an expansion block that can be released by impairing regulatory T cell associated signaling pathway

231 ch enhanced cardiomyocyte contractility, but impaired relaxation and evoked hypertrophic remodeling w

232 We propose that this actin-based impaired relaxation is central to NEM6 pathology.

233 Patients with ALD and impaired renal function have a higher risk of graft loss

234 ion, dyslipidemia, the metabolic syndrome or impaired renal function.

235 to learn sensory statistics, resulting in an impaired representation of the world.

236 to assess its performance in the presence of impaired respiratory and renal functions.

237 dramatically increased PDH activity, and an impaired response to mitochondrial stress in affected ce

238 However, diabetic females displayed impaired responsiveness to superovulation.

239 mitotic slippage due to defective AURKB and impaired SAC activity, downstream of condensin complex d

240 ve cortex (occipital place area) selectively impaired scene recognition.

241 ed with the decreased SERCA2a expression and impaired SERCA2 activity in lymphatic muscle.

242 ile elevated temperatures have been shown to impair short-run cognitive performance, much less is kno

243 tified single amino acid mutations result in impaired shRNA-mediated silencing.

244 This perturbation impairs sister chromosome linkage, advances the timing o

245 precursor protein knockin (APP-KI) mice with impaired spatial memory.

246 inhibiting de novo proline biosynthesis and impairing spheroidal growth.

247 cells show chromatid cohesion defects and an impaired spindle assembly checkpoint (SAC), thus undergo

248 d heteromeric receptors that contain binding-impaired subunits, as we show for both kainate and GluA2

249 on of membrane PI(4,5)P2 in cultured neurons impairs SV endocytosis, specifically in midbrain neurons

250 extrasynaptically located receptors that can impair synaptic plasticity.

251 However, these changes did not impair synaptic transmission and plasticity and synaptic

252 p2(+/R552H) mice) display motor deficits and impaired synaptic plasticity in the striatum.

253 strocyte lactate supply alone rescued stress-impaired synaptic plasticity, which was blocked by inhib

254 4 in mice results in cardiac hypertrophy and impaired systolic function, which could severely limit t

255 tricular-arterial coupling ratio, reflecting impaired systolic function.

256 H3K79me2 led to low expression of STAT5 and impaired T cell immunity.

257 Ablation of RagA alone impairs T reg cell accumulation in the tumor, resulting

258 Chemogenetic silencing of GC impaired task performance.

259 the E3 ligase Kelch-like protein 42 (KLHL42) impairs TGF-beta-dependent profibrotic signaling.

260 ently unclear whether hearing impairment may impair the ability to use selective attention to suppres

261 arrying the 5'UTR variant stabilize TP53 and impair the growth and differentiation of erythroid cells

262 deling showed that desynchronized inputs can impair the precision and stability of CA1 place cells.

263 th murine and human tumor cells, HOTAIR-sbid impaired the ability of HOTAIR to bind Snail and, in tur

264 lated modulation of CDh neurons and strongly impaired the classification of task-epochs based on CDh

265 fter the extinction session dose-dependently impaired the consolidation of fear extinction memory of

266 While this impaired the correction of erroneous KT-MT attachments,

267 lesser degree, deletion of just the B boxes impaired the de novo establishment of the heterochromati

268 Importantly, eEF1D impaired the interaction between NP and importin alpha5

269 the proximal Valpha genes, and its deletion impaired the Tcra rearrangement.

270 ent alterations in taste weaken satiation by impairing the central processing of sensory signals.

271 A mutation impairing the interaction of one of the two SEC7 domains

272 Klotho deficiency causes cardiac aging via impairing the Nrf2-GR pathway.

273 conclude that the tubulin mutation severely impairs the central hearing pathway most probably by pro

274 We further demonstrate that cross-linking impairs the cholesterol efflux mediated by apoA-I or HDL

275 Consequently, depletion of ZNF281 impairs the efficiency of the NHEJ repair pathway and de

276 lycosylation of NCSTN to its mature form and impairs the integrity of the gamma-secretase complex as

277 ater metabolic burden on larger individuals, impairing their physiological performance in the future.

278 act N4BP1 in caspase-8-deficient macrophages impairs their ability to mount robust cytokine responses

279 c itch greatly reduces the patients' QOL and impairs their daily activities.

280 r thermal stability; heating and/or freezing impairs their potency.

281 Impaired thermoregulation and lowered average daily gain

282 e emergence of EC neuronal hyperactivity and impaired theta rhythmicity.

283 Rather than impaired threat learning, pathological anxiety involves

284 due to prolonged intestinal inflammation and impaired tissue repair.

285 caspase-8/gasdermin-D (GSDM-D) renders mice impaired to produce both TNFalpha and IL-1beta and highl

286 tion and postoperative adjuvant chemotherapy impairs tolerability and feasibility and does not improv

287 ory T (Treg) cells (ie, FOXP3), resulting in impaired Treg function and autoimmunity.

288 Impaired Treg suppression in the absence of ERbeta was a

289 oclast metabolic quiescence, associated with impaired tricarboxylic acid (TCA) cycle function and met

290 Deficiencies in either LPL or GPIHBP1 impair triglyceride hydrolysis, resulting in severe hype

291 The venom was effective at impairing tumor development in murine xenogeneic model,

292 R7 were identified that were associated with impaired type I and II IFN responses.

293 chemical assays, that these mutations either impair UGDH stability, oligomerization, or enzymatic act

294 d alphaKlotho-hypomorphic mouse (kl/kl) with impaired urinary Pi excretion, low autophagy, and premat

295 ar fenestration after engraftment, partially impairing vascular permeability and glucose delivery to

296 both the African and Asian lineages of ZIKV, impairing virus dissemination to brain and sexual organs

297 Thus, our findings indicate that THC does impair visual working memory, and that this impairment m

298 e, cardiac output and O(2) delivery, thereby impairing VO2 peak and thus exercise capacity.

299 This response was impaired when the minimum EBE was fused with a thymidine

300 onstrate that hippocampal memory updating is impaired with aging and establish that the OUL paradigm