ライフサイエンスコーパス: imperative

1 of disease-modifying therapies against AD is imperative.

2 g effective privacy-protecting solutions are imperative.

3 the under-ascertainment of RSV infection is imperative.

4 gesting use of a human-derived model remains imperative.

5 ent outputs (not just the positive ones) are imperative.

6 arize such a set T of cancer phylogenies are imperative.

7 ween organelles and cell to cell response is imperative.

8 pplications where accurate quantification is imperative.

9 tions in 2018, a highly effective vaccine is imperative.

10 iate accelerated in vitro release methods is imperative.

11 to cause eutrophication, and its removal is imperative.

12 ptimizing care in this patient population is imperative.

13 to health systems is an ethical and economic imperative.

14 evant in vitro podocyte models is a clinical imperative.

15 f novel therapeutic targets for this disease imperative.

16 municating the reliability of MFA results is imperative.

17 Maximizing their effectiveness is imperative.

18 its consequences, prevention of delirium is imperative.

19 the understanding of their binding kinetics imperative.

20 s as pathogenic or non-pathogenic has become imperative.

21 to assess the cell type specific response is imperative.

22 olved in drug resistance or sensitization is imperative.

23 g peoples, represents an entirely achievable imperative.

24 o makes sufficient type one error correction imperative.

25 ity loss across the planet by 2020-an urgent imperative.

26 uction and escape from Nab activity is still imperative.

27 of Ahr-mediated responses to xenobiotics is imperative.

28 ntribute to SCC, studies of ESPC biology are imperative.

29 ty controls for clinical-grade hiPSCs remain imperative.

30 rdination and assessment of animal models is imperative.

31 and promotion of lifestyle modification are imperative.

32 acts, tackling plant pathogens is an ethical imperative.

33 and outreach-based sexual health services is imperative.

34 tolerability of treatment to the patient are imperative.

35 and safe "next-step" treatments are clinical imperatives.

36 tive collaboration despite social distancing imperatives.

37 cipients to be treated at home, and economic imperatives.

38 g that is often needed to satisfy functional imperatives.

39 nce make malaria elimination both viable and imperative, although this may be more easily achieved in

40 has been proved in terms of sensitivity and imperative analytical parameters.

41 ting unknown molecule identification is both imperative and challenging.

42 tunity for surgeons to embrace this national imperative and improve our practices.

43 , electrical characterization of graphene is imperative and requires the measurement of work function

44 ors for MBC continues to be a major research imperative, and one which can lead to advances in breast

45 ifficult, it is scientifically and ethically imperative, and there is an expanding analytical toolbox

46 ld where environmental conditions and social imperatives are constantly shifting.

47 close the gap in the care cascade by race is imperative, as are efforts to increase serodiscussion an

48 n of endotypes is also becoming increasingly imperative because targeted biotherapeutic agents, such

49 in-injured patients, reliable biomarkers are imperative before any preclinical therapeutics can find

50 Sample outlier detection is imperative before calculating a multivariate calibration

51 ance or finding more efficient treatments an imperative challenge.

52 nts have been studied for their potential as imperative components of fuel cell technology.

53 characteristic curve of 0.80 +/- 0.04 before imperative cues when the demanded action was known ahead

54 ional treatment options available, increased imperative exists to better characterise patients to ena

55 R gene therapy trials are underway, a future imperative exists to determine which carriers require in

56 e frequency of stressor interaction types is imperative for a better understanding of how stressors a

57 ion variation, and underscore the scientific imperative for a broader characterization of the genomic

58 g coverage and carefully tuned algorithms is imperative for a clinical assay.

59 Despite the rarity of POC, it is imperative for a radiologist to be aware of its wide spe

60 f the IDT unit and the benzothiadiazole, are imperative for achieving high hole mobilities in this re

61 s the epidemic of tobacco-caused disease, an imperative for action documented by epidemiologic resear

62 Accurate stratification of tumors is imperative for adequate cancer management.

63 come increasingly important, resulting in an imperative for an intersecting discipline: cardio-oncolo

64 x residues (Arg-Phe-Phe-Asn-Ala-Phe) that is imperative for binding and function.

65 suggest that complete neutralization is not imperative for bnAbs to prevent infection but that with

66 Real-time imaging of immunoactivation is imperative for cancer immunotherapy and drug discovery;

67 by the TMTC1-4 genes, which were found to be imperative for cdh and pcdh O-Man glycosylation.

68 d understanding antimicrobial resistance are imperative for clinical practice to treat resistant infe

69 This discovery is imperative for developing clinical strategies that might

70 on and especially metastatic progression are imperative for developing novel treatment strategies.

71 doscopic surveillance of patients with BE is imperative for early detection and treatment of dysplasi

72 rient storage and partitioning in forests is imperative for ecosystem models and ecological theory.

73 ecological and epidemiological processes is imperative for effective disease management.

74 for fire-promoting invasive grasses will be imperative for effectively managing ecosystems.

75 deep tissue damage caused by UV radiation is imperative for ensuring the health and safety of living

76 ve from negative dengue infection samples is imperative for epidemic control and public health in tro

77 linical and clinical results underscores the imperative for establishing good animal models, then gle

78 elaxor-, organic- and anti-ferroelectrics is imperative for exploiting new flexible and room-temperat

79 is returned to lower charge/discharge rates, imperative for future energy storage devices.

80 ite consumption expansion and the structural imperative for growth in competitive market economies in

81 However, chemokine receptors are imperative for guiding cells out of the SCS, and for the

82 ontrolled regulation of lineage decisions is imperative for hematopoiesis.

83 ors such as the capacity to conserve and the imperative for human development.

84 ge carrier generation and their diffusion is imperative for improving the efficiency of optoelectroni

85 tanding of gas exchange mechanism in ARDS is imperative for individualized symptomatic support of pat

86 boundary currents, our findings highlight an imperative for its representation in models of oceanic o

87 are fully developed in the mature liver are imperative for life.

88 that early control of protein homeostasis is imperative for long-term neuronal survival.

89 l malformations, the ZIKV epidemic became an imperative for mobilization, renewed strategies for vect

90 ve that conceiving behavior in these ways is imperative for neuroscience.

91 ugh which genetic risk causes dementia is an imperative for new therapeutic development.

92 of the olfactory ensheathing cells (OEC) is imperative for normal GnRH-1 neuronal migration.

93 en a soft and a stiff endothelial surface is imperative for proper functioning of the endothelium.

94 cell fate through oriented cell division is imperative for proper organ development.

95 sed payments for bundles of care advance the imperative for radiology providers to articulate their v

96 Assessment of regeneration potential is imperative for scaling out FMNR and where natural regene

97 Debugging a genome sequence is imperative for successfully building a synthetic genome.

98 derstanding of spatio-temporal movements are imperative for the conservation of this species.

99 e for the maintenance of neuropathic pain is imperative for the development of more efficacious thera

100 provide atomic-resolution structural details imperative for the development of vaccines and antiviral

101 chemically selective MRI contrast agents is imperative for the early detection and diagnosis of many

102 action of Li ions from a cathode material is imperative for the functioning of a Li-ion battery.

103 ering that maintenance of stable activity is imperative for the robust function of the nervous system

104 sions using informative molecular markers is imperative for their genetic improvement and conservatio

105 zation of metal-organic frameworks (MOFs) is imperative for their wider adoption in industry and prac

106 We propose that Irf4 is imperative for thymic Treg homeostasis because it regula

107 the development of genomic technologies, the imperative for translational impact of National Institut

108 ming and intensity of migratory movements is imperative for understanding impacts of changing landsca

109 here could still be a significant adaptation imperative for vulnerable urban populations.

110 Establishing a genetic diagnosis is imperative for WT families so that individuals harboring

111 oolers and heightened clinical awareness are imperative given the consequences of infection.

112 to prevent the spread of 3GC resistance are imperative; however, suitable approaches to antimicrobia

113 cidating the source of these associations is imperative in achieving the promise of the national Prec

114 r cells, either locally or at distances, are imperative in both normal and pathological conditions.

115 resolution and shorten antibiotic therapy is imperative in curbing the global tuberculosis epidemic.

116 transmission in historical Europe, which is imperative in demonstrating how pandemics were spread in

117 Appropriate imaging is imperative in evaluating children with a primary hepatic

118 e regeneration (GTR) in furcation defects is imperative in order to obtain predictable regeneration o

119 s a result, comprehensive genetic testing is imperative in patients who meet the current testing crit

120 onsideration of risk-spreading strategies is imperative in studying plant life-history evolution.

121 Interactive data visualization is imperative in the biological sciences.

122 al and potentially also genomic risk data is imperative in the initial management of men with prostat

123 stems remain extensive and human development imperative is greatest).

124 This distinct evolutionary imperative is reflected in structural and functional fea

125 ionate nursing care nor addresses the policy imperative it was intended to target.

126 association with severe sequels, there is an imperative need for new JIA diagnosis strategies.

127 e prevention of COVID-19 transmission, it is imperative not to undermine recent progress made in the

128 professional organizations and predates the imperative of ID physician leadership in ASP.

129 the unequal worth of human beings, the moral imperative of preserving a pure Aryan people, the author

130 note the fledgling state of the science, the imperatives of editing efficiency, specificity, and unif

131 Recent studies have highlighted the imperatives of including diverse and under-represented i

132 on) and epistemic (uncertainty minimization) imperatives on an equal footing - as primary determinant

133 on, yet socio-cultural transmissions, though imperative, play an auxiliary role of transcribing perce

134 mechanisms of the metabolizing enzymes is an imperative prerequisite for informed EDTA bioremediation

135 Increased awareness among clinicians is imperative, promoting early diagnosis of APRT deficiency

136 Lastly, we discuss imperative questions remaining to be answered.

137 newly developed WFHE along with a summary of imperative requirements of material properties, sensor c

138 Imaging and image-guided procedures play an imperative role in the screening, diagnosis, and surveil

139 Our observations demonstrate an imperative role of PTEN in global transcriptional regula

140 -bonding interactions are the reason for the imperative sensing property of TL18 for picric acid.

141 maternal and child health programmes make it imperative that a similar intervention that establishes

142 Thus, it is imperative that accurate, timely, and robust disease det

143 Thus it is imperative that allergists understand the differences in

144 ion of Cardiovascular Sciences (DCVS), it is imperative that DCVS and the Extramural Research communi

145 mprove the prognosis of such patients, it is imperative that every health-care provider be aware of t

146 e of this pathway in pediatric cancer, it is imperative that future studies strive to better understa

147 evelopment of new antifungal drugs a medical imperative that in recent years motivates the talents of

148 of antibodies against SARS-CoV-2, it remains imperative that laboratories thoroughly evaluate such as

149 to prevent metabolic disease, and thus it is imperative that molecular players that maintain neuronal

150 It is imperative that multi-component intervention be implemen

151 d for multivariate analyses increases, it is imperative that optimal tools are available to assess th

152 To further reduce ART attrition, it is imperative that patient education and healthcare provide

153 n the complex nature of the procedure, it is imperative that patients are selected appropriately, and

154 It is imperative that policy makers urgently ensure the integr

155 It is imperative that public health approaches, including thos

156 th delivery systems being overwhelmed, it is imperative that safe and effective pharmacotherapeutic s

157 campal atrophy in Alzheimer's disease, it is imperative that techniques are developed for detection o

158 silent spread by asymptomatic persons, it is imperative that testing programs include those without s

159 It is now imperative that the field focus on empowering more A/I s

160 rder to realize an "overall zT > 2.0," it is imperative that the interrelated properties are decouple

161 It is imperative that the radionuclide remain attached to the

162 It is imperative that these gases are mitigated in an environm

163 cells initiate the meiotic divisions, it is imperative that they finish meiosis.

164 d limitations of experimental methods, it is imperative that this problem is tackled computationally.

165 It is therefore imperative that water quality management strategies acco

166 However, it is imperative that we anticipate the potential impact on th

167 curity posed by rumen fluke infection, it is imperative that we develop a better understanding of the

168 For disease-associated genes, it is imperative that we differentiate a sequence variant as e

169 The authors believe it is imperative that we expand the use of therapies proven to

170 Given the pace of climate change, it is imperative that we inform and accelerate adaptation prog

171 e data contain the blueprint for life, it is imperative that we interpret it accurately.

172 to increasing susceptible populations, it is imperative that we investigate how Candida albicans inte

173 Thus, it is imperative that we investigate the pathogenesis of adeno

174 tures rising at an unprecedented rate, it is imperative that we know how aquatic insects respond to i

175 esilience to climate change worldwide, it is imperative that we protect and harness the benefits that

176 It is imperative that we reassess our current recruitment stra

177 It is therefore imperative that we understand how the supply of chromati

178 lly detrimental outcomes of wildfires, it is imperative that we understand the response of ecosystems

179 ancy and during labour and childbirth, it is imperative that with INAP in place, India aspires to doc

180 The imperatives that guide model construction under the epis

181 ptic nonreciprocal systems on chip have made imperative the exploration of magnet free alternatives.

182 lains how kinetic gating in the D-channel is imperative to achieving high proton-pumping efficiency i

183 ity of the lithium (Li) metal battery, it is imperative to address the dendrite growth and interface

184 The discovery of new antiviral therapies is imperative to address this challenge, and antiviral pept

185 It is imperative to advance our understanding of heterogeneiti

186 humans may influence population structure is imperative to allow for informed decisions in management

187 power is expanding rapidly worldwide, it is imperative to assess its promise under future climate sc

188 about nonhuman primate research has made it imperative to attempt to clearly articulate the potentia

189 It is imperative to augment quantity and diversity of genome-w

190 Detection of pathogenic bacteria is imperative to avoid and/or fight their potential harmful

191 technique and caution in high-risk angles is imperative to avoid cyclodialysis.

192 ow I Treat" review highlights the overriding imperative to avoid harm in caring for patients with SR-

193 ated synaptic activity and TrkB signaling is imperative to BDNF's suppressive effect on drug-seeking.

194 justifying early intervention efforts, it is imperative to better understand underlying biological me

195 Real-time multiplex imaging is imperative to biology and diagnosis but remains challeng

196 lmark of many pathophysiological process, is imperative to both understanding the precise roles of RO

197 Imperative to capture patient-reported outcomes was driv

198 Thus, it is imperative to characterize the breeding germplasms using

199 or plant metabolism of these CECs, making it imperative to consider conjugates when assessing their r

200 fulfills the mission of saving lives, it is imperative to consider the consequences not only to our

201 about the role of social associations it is imperative to consider the multidimensional nature of so

202 stic artificial intelligence (AI) create the imperative to consider the opportunities and risks of in

203 rbide dihydride structure implies that it is imperative to consider this often-neglected class of car

204 the interrogation of African genomes, it is imperative to continue and increase our efforts to descr

205 therapeutic antiviral drugs against hRSV is imperative to control the burden of disease in the susce

206 ell-mediated immunity to malaria has made it imperative to define and reconcile the mechanisms that r

207 t memory and signal processing capability is imperative to deploy efficient brain-like vision systems

208 vivo generated dendritic cells (DCs), it is imperative to design strategies that harness specialized

209 Accordingly, it is imperative to detect and diagnose the disease as early a

210 Therefore, it is imperative to determine the ability of strains to faithf

211 ber of BL enzymes is increasing daily, it is imperative to develop a computational tool to classify t

212 Thus, it is imperative to develop a robust deconvolution method that

213 netic multilayers is an open question, it is imperative to develop comprehensive understanding of sky

214 Therefore, it is imperative to develop more sophisticated and more biomim

215 nt virulence of vegetative cells has made it imperative to develop newer modalities of treatment.

216 As such, it is imperative to discern the underpinning mechanisms by whi

217 s involved in neurodegenerative disorders is imperative to discover novel genetic risk factors and po

218 itional methods for freshwater generation is imperative to effectively address the global water short

219 velopment can take a decade or longer, it is imperative to effectively use currently available drugs.

220 igh-throughput sample processing workflow is imperative to ensure sensitive, quantitative, and reprod

221 nderstanding of all associated toxicities is imperative to ensure that patients can achieve maximal c

222 the requisite health-care infrastructure are imperative to ensuring optimal patient outcomes, especia

223 iveness of all types of interventions, it is imperative to establish strong and broad partnerships ac

224 outcomes after pediatric critical illness is imperative to evaluate practice and improve recovery of

225 er, given their increasing popularity, it is imperative to evaluate the health risks of e-cigarettes,

226 atment is finished, observing the patient is imperative to evaluate the treatment methodology and adj

227 f the biomedical and clinical communities is imperative to expand the available therapeutics beyond a

228 had severe socioeconomic consequences, it is imperative to explore novel approaches to monitoring and

229 Therefore it is imperative to explore the mechanisms that result in LSC

230 Therefore, it is imperative to find environmentally-friendly metal ions t

231 completed Phase III clinical studies, it is imperative to gain a better understanding of its mechani

232 Thus, it is imperative to gain a better understanding of the relatio

233 cture in a dynamically controlled way, it is imperative to gain access into the intrinsic dynamics of

234 tuberculosis, drug susceptibility testing is imperative to guide therapy.

235 It is imperative to highlight them for immunological screening

236 ronments provide goods and services that are imperative to human survival and well-being (for example

237 erefore, comprehensive studies like ours are imperative to identify CRM1 cargoes with real pathogenic

238 ients are responsive to immunotherapy, it is imperative to identify factors impacting outcome.

239 It is imperative to identify new targets for improved vaccines

240 obal increase in salinity levels has made it imperative to identify novel sources of genetic variatio

241 of nuclear exposure is heightened and it is imperative to identify potential countermeasures for acu

242 Such standards are imperative to implementing summative assessments into su

243 mic cost of a tree disease, and the economic imperative to improve biosecurity may have been underapp

244 Combinatorial therapeutic approaches are an imperative to improve cancer treatment, because it is cr

245 Further research is imperative to improve diagnosis and identify effective t

246 ation while suppressing effector immunity is imperative to improve graft survival and minimize conven

247 ts to eliminate coal as an energy source are imperative to improve public health and avert serious cl

248 f integrated multidisciplinary approaches is imperative to improve the diagnosis, prevention, and tre

249 n (N) and phosphorus (P) in urban systems is imperative to improving water quality and better managin

250 It is imperative to increase confidence in long-term predictio

251 tanding of the methodology behind Tac IPV is imperative to its recognition as an important prognostic

252 and imaging studies were negative if it was imperative to know whether active Crohn's disease was pr

253 ng best practices for SPK transplantation is imperative to mitigate racial disparities in outcomes ob

254 lution and propagation of resistance is thus imperative to mitigating loss of intervention effectiven

255 ally those with new insecticides, it will be imperative to monitor their comparative durability to en

256 To further improve device performance, it is imperative to obtain fundamental understandings on the p

257 magnitude between individuals, making it an imperative to obtain individual baseline measurements if

258 diagnosis and subtyping of kidney tumors are imperative to optimize and personalize treatment decisio

259 example greywater, such an understanding is imperative to optimize designs for successful long-term

260 ater relations of microbial extremophiles is imperative to our ability to increase agricultural produ

261 yses of site-specific antibody responses are imperative to our assessment of the quality of vaccine-i

262 configurable molecular diagnostic tests are imperative to prevent global spread of new diseases.

263 mbers of people in need and the humanitarian imperative to reduce suffering, there is an urgent need

264 Therefore, exploring soil legacy P is imperative to reduce the demand for mineral fertilisers

265 Although a clinical diagnosis, imaging is imperative to rule out associated complications which ap

266 The prevention of T2D has become imperative to stem the rising rates of this disease.

267 t the PD of VGCC undergoes hysteresis, it is imperative to study its gating process in the absence of

268 Given the crucial role of PIP2, it is imperative to study its localization, interaction with p

269 stand community composition, it is therefore imperative to study the impact of resource fluctuations

270 Hence, it is imperative to study the structural characteristics of th

271 rstand these hydrogen bonded networks, it is imperative to study these systems as dynamic entities us

272 fitness in their environmental niches, it is imperative to study viruses at the site of initial repli

273 ounds, particularly in a kinetic format, are imperative to the development of drugs with improved eff

274 ing of the basic biology of these targets is imperative to the development of effective cancer immuno

275 As sporulation is imperative to the successful transmission of C. difficil

276 c stresses due to climate variability, it is imperative to understand and minimize the negative impac

277 at are important for vector reproduction are imperative to understand and predict infection prevalenc

278 s are being lost at alarming rates and it is imperative to understand how communities assemble if we

279 It is imperative to understand how naturally mediated changes

280 ium and sodium ion battery technology, it is imperative to understand how the properties of the diffe

281 It is imperative to understand its damage-tolerant behaviour a

282 tance, a growing global health threat, it is imperative to understand its drivers and underlying biol

283 thione and redox homeostasis, and thus it is imperative to understand the enzymes and the mechanisms

284 lead to the development of PTSD, it is first imperative to understand the interplay which exists betw

285 Therefore, it is imperative to understand the mechanisms underlying myofi

286 ellular physiology and viral disease make it imperative to understand the membrane scission mechanism

287 fungal pathogens have on human health, it is imperative to understand the molecular mechanisms that g

288 These policy mechanisms have made it imperative to understand the potential cost savings of q

289 ay be detrimental to bacterial growth, it is imperative to understand the strategies employed by bact

290 utilize these materials in technology, it is imperative to understand their thermodynamic stability,

291 recent trend of rapid urbanization makes it imperative to understand urban characteristics such as i

292 Thus, it is imperative to understand which cancers are oncogenically

293 itivity of pathogen recognition receptors is imperative to understanding infection and inflammation.

294 ic communities are grappling with monumental imperatives to contain COVID-19, develop effective vacci

295 We propose policy imperatives to protect and support health workers workin

296 be balanced with (a) the moral and statutory imperatives to reduce inequities resulting from socioeco

297 rowth in the market for electric vehicles is imperative, to meet global targets for reducing greenhou

298 and perfect understanding of the disease are imperative toward efficient treatments.

299 Mechanical ventilation remains an imperative treatment for the patients with acute respira

300 To address this, it is imperative we understand transmission dynamics in this p