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3 xate on anabolic and catabolic processes and implicate AMPK activation as a metabolic determinant of
9 uced alterations in GPCR internalization and implicate beta-arrestin as a potential player mediating
10 mic brainstem pathways to hypoxic stress and implicate brainstem SD as a previously unrecognized site
14 iated metabolic remodeling in beta-cells and implicate CDK1 as a regulator of complex I that enhances
20 der and inhibits DNA repair in lung tissues, implicate ECS as a lung and potential bladder carcinogen
27 a neuronal migration disorder, and our data implicate GCP2 as a core component of gamma-TuRC in neur
33 te insulin resistance in human diabetes, and implicate hDia1 as a potential mediator of AGE-ECM-adipo
34 way to categorize EAC at a genome scale and implicate HNF4A activation as a potential pivotal event
38 building on several recent publications that implicate IgM as a crucial molecule that determines both
42 at IQGAP1 is a scaffold for IR and IRS-1 and implicate IQGAP1 as a participant in insulin signaling.
44 9a as novel enhancer-associated factors, and implicate Jmjd2c as a molecular scaffold for the assembl
47 ation tolerance by donor apoptotic cells and implicate MerTK agonism as a promising target for promot
49 atures of Brown-Vialetto-Van Laere syndrome, implicate mitochondrial dysfunction as a downstream cons
55 rgence of genetic and functional evidence to implicate OPC dysfunction as a candidate pathophysiologi
57 B or PDGF receptor-beta cell interactions to implicate PDGF-BB as a primary effector of MM cell vascu
60 and injury-induced vascular remodeling, and implicate PLD2 as a candidate target for therapeutic int
62 ism that regulates CNS axon regeneration and implicate primary cilia as a regenerative signaling hub.
65 in the restriction of viral pathogenesis and implicate RIPK3 as a key coordinator of immune responses
66 h in primary human lung and intestinal cells implicate SADS-CoV as a potential higher-risk emerging c
70 e for alternative TDP43 isoforms in ALS, and implicate sTDP43 as a key contributor to the susceptibil
71 al "functional mystery." Recent publications implicate Ste24 as a key factor in several endoplasmic r
76 r studies in yeast and mammalian tumor cells implicate the mitochondrion as a target of artemisinins,
77 how p97 maintains lysosomal homeostasis, and implicate the pathway as a modulator of degenerative dis
78 as potent regulators of ILC2 activation and implicate their utility as a therapeutic approach for th
80 s in regulating cardiac stress responses and implicate this pathway as a potential target in human he
81 e signalling in regulating p53 stability and implicate this pathway as a promising therapeutic target
84 tiffness and tunability of the I-band spring implicate titin as a force contributor that, during cont
85 t determinant of VLDL metabolism and further implicate TM6SF2 as a causative gene underlying metaboli
93 d to fibrosis development from Sav1 loss and implicate VP as a potential pharmacological inhibitor to
99 rofiling of C3-deficient cultured astrocytes implicated EGFR signaling as a hub in C3-dependent respo
100 ing genetic association with gene expression implicated FLCN as a disease gene for diabetic retinopat
101 studies of HDAC7 in cultured cardiomyocytes implicated HDAC7 as a prohypertrophic signaling effector
102 ecifically in CD11c-expressing cells in vivo implicated macrophages as a critical innate immune contr
103 ed under standard laboratory conditions have implicated Mg2+ as a primary mediator of ribosomal struc
104 ranscriptome data from CDCexo-primed Mvarphi implicated miR-181b as a significant (P=1.3x10(-21)) can
107 S and add to a growing body of evidence that implicates cerebrovascular disease as a core feature of
110 ating intestinal self-renewal with BA levels implicates FXR as a potential therapeutic target for CRC
112 astatic phenotype in ER(+) breast cancer and implicates IKKbeta as a driver of certain features of ag
114 hts into the biological roles of GPC SSP and implicates it as a good target for the development of an
115 OTUB1 as a key regulator of ferroptosis and implicates it as a potential target in cancer therapy.Se
118 ient selection and treatment evaluation, and implicates LINC00473 as a therapeutic target for LKB1-in
120 pregnancy complications, increasing evidence implicates maternal obesity as a major determinant of of
122 ed role in regulating mitochondrial fission, implicates MTP18 as a downstream component of axon regen
124 ose that are involved in RNA processing, and implicates phosphorylation as a mechanism that regulates
125 hanism for regulating tankyrase activity and implicates PrxII as a targetable antioxidant enzyme in A
127 rces are distributed over memory targets and implicates selective attention as a main gating mechanis
128 ly unrecognized disease of mtDNA maintenance implicates SSBP1 mutations as a cause of human pathology
130 erative signaling and induces cell death and implicates this combination as a promising therapeutic s
131 se a unique heme biosynthesis pathway, which implicates this pathway as a target for development of a
132 -infiltrating T cells following Yap deletion implicates Yap as a mediator of global T-cell responses
133 ysis without correcting cholesterol storage, implicating aberrant mTORC1 as a pathogenic driver downs
134 ariability of tDCS-induced effects, not only implicating age as a crucial modulating factor, but deta
135 cholesterol metabolism and Notch signaling, implicating AIBP as a possible druggable target to modul
136 lay an important role for its activity, thus implicating arginine methylation as a novel regulatory m
138 1 are within a potentially druggable pocket, implicating Bag-1L as a potential therapeutic target in
139 nduce significant hypomyelination pathology, implicating c-Jun as a potential player in demyelinating
140 pertrophy, ECM remodeling, and inflammation, implicating CatA as a potential therapeutic target to pr
141 quired for perinuclear localization of Myo2, implicating Csm4 as a regulator of the Mps2-Myo2 interac
142 roved renal health in diverse models of CKD, implicating dynamin as a potential therapeutic target fo
144 eased both cyclin B1 protein and RNA levels, implicating FoxM1 as a critical target for cyclin B1 inh
145 xpression of both cyclin B1 protein and RNA, implicating FoxM1 as a critical target mediating MVM-ind
146 utations are predominantly loss-of-function, implicating haploinsufficiency as a frequent mechanism.
149 o modulate Th9 cell differentiation, thereby implicating IRF8 as a potential therapeutic target to af
150 be improved via inhibition of HDAC6, further implicating it as a potential therapeutic target for CF.
151 es that are essential for virus replication, implicating it as a potentially good target for developi
152 and reduced antitranscriptional activities, implicating M as a primary regulator of cytopathicity an
153 egeneration in both flies and human neurons, implicating mitochondrial dysfunction as a mechanism in
154 modulating multiple age-associated pathways, implicating mTORC1 as a therapeutic target to treat sarc
155 site intermediates by interacting with APE1, implicating MUTYH as a factor that modulates the delicat
156 duced interval Bbaa1 congenic mice, formally implicating myostatin as a novel downstream mediator of
157 nfiltration into the tumor microenvironment, implicating NSD1 as a tumor cell-intrinsic driver of an
159 d glucose uptake in skeletal muscle cells by implicating p41ARC as a new component of the insulin-sig
160 , and genetic inhibition of endothelial NOS, implicating peroxynitrous acid as a key damaging agent.
161 ter geographic spread of non-native species, implicating phenology as a potential trait associated wi
162 to the occipital visual areas in carnivores, implicating PMLS as a potential gateway to the parietal
163 familial form of Alzheimer's disease (AD) by implicating PrP(C) as a potential therapeutic target for
164 equired for persistent PrP(res) propagation, implicating raft microdomains as a location for conversi
165 gistic growth inhibition of MDA-MB453 cells, implicating Src as a mediator of resistance to HER2-targ
167 ssion of TBXT increased viability, therefore implicating TBXT as a potential therapeutic target of H3
168 tem cell (HSC) self-renewal/differentiation, implicating TET2 as a master regulator of normal and mal
169 e decision making; and add to the literature implicating the insula as a key brain region in addictio
170 sosomal biogenesis, transcription factor E3, implicating the LFC as a checkpoint in mTORC1 signaling.
172 subjects recognized distinct IGRP peptides, implicating this molecule as a trigger for CD4(+) T cell
173 pressed below tight junctions (TJ), strongly implicating TJ disruption as a critical step in antigen
174 asing SYP41-SYP61 t-SNARE complex formation, implicating TNO1 as a tethering factor mediating efficie
175 nt blockade is enhanced in Ythdf1(-/-) mice, implicating YTHDF1 as a potential therapeutic target in
182 nt active site with PARP1 or PARP2, our data implicate HPF1 as an important determinant of the respon
190 3 expression, whereas functional predictions implicated ABLIM1 as an allele-specific expressed gene i
192 al studies using human ccRCC cell lines have implicated HIF-1alpha as an inhibitor and HIF-2alpha as
194 th differential microbicidal activities, and implicated macrophages as an intracellular niche for pat
199 ata to better understand prior research that implicates pharmaceutical promotions as an important fac
201 or Cordilleran Ice Sheet retreat and instead implicates the Pacific as an early part of a cascade of
202 lleviated these vascular phenotypes, further implicating ANGPT2 as an important TGFbeta downstream me
204 ides a simple model for tissue regeneration, implicating cellular reprogramming as an essential eleme
205 oforms is observed in multiple malignancies, implicating EVI1 as an oncogene, while PRDM3 has been su
206 extent than has been previously appreciated, implicating phase separation as an evolutionarily ancien
207 r of glioma-associated alternative splicing, implicating SRSF3 as an oncogenic factor that contribute
209 olorectal cancer cases than controls and may implicate homocysteine metabolism as another causal path
210 chromatin and transcriptional profiling, we implicate IRF2 as antagonistic to stemness and show that
214 ctive and efficient organocatalysis in water implicates cysteine as both catalyst and precursor in pr
215 ty in diseases where these viruses have been implicated, such as cancer and neurological syndromes.
216 -induced senescence and validated previously implicated genes such as CDKN1A We developed an innovati
217 centromeres of a premier model organism and implicates retroelements as conserved features of centro
219 ncephalomyelitis, a murine model of MS, thus implicating both homologs as copathogenic contributors.
220 Lesion studies of the EC provide evidence implicating this region as critical for memory and the f
221 xclusively attributed to myofibroblasts, and implicate macrophages as direct contributors to fibrosis
226 rsenate, nitrate and selenate, respectively, implicating these genes as encoding the catalytic subuni
228 ide antagonist and genetic analyses together implicate SERK proteins as essential coreceptor kinases
230 analyses of viral and host RNAs converge to implicate RPLP1/2 as functionally important for ribosome
231 addictions where brain opioid receptors are implicated, such as gambling disorder and alcohol use di
232 mutated ETS, AP-1, and NF-kB binding motifs, implicating these motifs as governors of EC regulation.
233 and altered leaf morphology and phyllotaxy, implicating PP2C phosphatases as growth regulators funct
236 agnitude of arrestin-mediated signaling, and implicate these sequences as important determinants of f
237 The muM affinity of polysulfides for IDO1 implicates these polysulfides as important signaling fac
238 In this review, we summarize recent results implicating R-loops as important regulators of cellular
239 rgely independent of cellular life, strongly implicating them as important drivers of global biogeoch
241 in, ghrelin, and dopamine signaling pathways implicating them as integrators of central and periphera
244 ched in humans following anti-cancer therapy implicates CSCs as key contributors to tumor dormancy, m
247 entify IL-21(+)CD4(+) T cells as pTfh cells, implicating them as key populations in the generation of
249 ulthood recapitulate the original phenotype, implicating local environment as mediators of microglial
251 ve transcriptional and metabolomics analyses implicate MYB15 as necessary for the defense-induced syn
254 rophysiological and selective in vivo levels implicate this enzyme as playing a key role in the integ
256 prunae transcriptome during 'uranium-shock' implicated VapC toxins as possible causative agents of t
257 es in examination of panic disorder (PD) has implicated several variants as potential susceptibility
258 on of HERVs in myeloid malignancies, thereby implicating HERVs as potential targets for immunotherape
259 drug atorvastatin ameliorated the pathology, implicating statins as potential therapeutics against a
260 duced phosphorylation of SFKs, Syk, and Pyk2 implicating SKAP2 as proximal to their activation in pat
261 on emission tomography (PET) imaging studies implicate cholinergic changes as significant contributor
263 tical roles in MET, and substantial evidence implicates these TMCs as subunits of the MET channel.
264 e for the glycation of cellular proteins and implicates FN3K as targetable modulator of NRF2 activity
265 plication of this strategy to human lymphoma implicates immunoglobulin neoantigens as targets for lym
268 mediates obesity-induced BBB breakdown, and implicate cerebrovascular dysfunction as the mechanism f
269 lls disrupts the BBB in dietary obesity, and implicate cerebrovascular dysfunction as the underlying
272 ved differences in catalytic efficiency that implicate kinetics as the determinant for species-specif
273 ive assay for pff uptake in primary neurons, implicate lysosomal processing as the major fate of inte
275 esting could improve antibiotic safety, help implicate vancomycin as the causal drug, and preserve fu
276 trations or BT composition within all events implicate vehicle fluids as the key source of BTs in bot
279 ets peroxidase and lncRNA TCONS_00951105 are implicated in acting as the competing endogenous RNA to
281 uld be pivotal in engendering resistance and implicates chloroplasts as the primary sites driving gly
282 Rab4, but IGF1R-AP2A1/2-clathrin with Rab11, implicates Flot-1 as the adaptor for faster recycling an
284 ssue nutrients were elevated, and deltaN(15) implicates sewage as the source, demonstrating transport
285 CXCL9 expression in lesional macrophages implicates the skin as the source of circulating cytokin
287 osylbenzene could also produce mycocyclosin, implicating compound I as the initial oxidizing species.
288 ormance for both small and large quantities, implicating efficient representation as the common origi
289 blockers UCL 1684 + TRAM 34 attenuated ROV, implicating endothelial hyperpolarization as the underly
290 stabilize Rab substrates on membranes, thus implicating GEFs as the primary determinants of Rab loca
291 ent Hedgehog (Hh) pathway mutations in BSCs, implicating Hh deregulation as the primary driving event
292 cking SKCa and IKCa channels attenuated ROV, implicating hyperpolarization as the underlying signal.
293 sociations but not corepressor associations, implicating partial agonism as the main driver of its di
294 ntaining a substrate compatible TE, directly implicating this domain as the major catalytic gatekeepe
295 as a tumor suppressor in the adult colon and implicate Hippo kinases as therapeutic vulnerabilities i
297 The variants associated with both outcomes implicate new pathways as well as targets of existing dr
298 f long-term memory and define general memory-implicated genes as well as conditioning-type-dependent
299 ance of proper brain circuitry, and has been implicated in neurodevelopmental as well as neurodegener
300 ing the amyloid beta peptide (Abeta) that is implicated in preeclampsia as well as with Alzheimer's d