ライフサイエンスコーパス: implicate @2 in

1 Importantly, these findings implicate MSLN in a benign disease, indicating that the

2 Our results implicate RFT1 in a wider range of glycosylation process

3 lerance in the immune system, these findings implicate the PSGs in a potential immune tolerance mecha

4 nal organization and connectivity of the DCN implicate them in a variety of sensorimotor functions, b

5 Our results implicate vinculin translocation in a molecular switchin

6 Mechanistic studies implicated CD28 in activating AKT signaling, T-cell prol

7 Recent evidence implicates amyloid oligomers in AD neuropathology, but t

8 to Abeta and forming amyloid fibrils, which implicates T40 in AD pathology.

9 are enriched in myeloid-specific enhancers, implicating myeloid cells in AD etiology.

10 pproach using previous evidence in the field implicating them in AD.

11 variants (CNVs) in genes/regions previously implicated in NPD in adults with EO (n = 149) referred f

12 A growing body of recent evidence, however, implicates FMOs in aging, several diseases, and metaboli

13 identified the cell types that express genes implicated in glaucoma in all five species.

14 after FcepsilonR1 stimulation in mast cells, implicating a role in allergy.

15 These findings implicate dopamine in an integration of momentary physic

16 aim of this study was to examine previously implicated genetic markers in and near IL1RAP in relatio

17 esion kinase (FAK), in endothelial cells has implicated its requirement in angiogenesis and tumour gr

18 ugh several of our candidate genes have been implicated in HF in animal models, independent replicati

19 nt phasiRNAs are enriched in meiotic stages, implicating these phasiRNAs in anther and/or pollen deve

20 Our results implicate vHMM-HA in anti-aging mechanisms and suggest t

21 rs and context-independent fear memory, thus implicating TMEM16B in anxiety modulation.

22 We implicate 69 genes in ASD risk, including 24 passing gen

23 Recent studies unexpectedly implicate HIF in aspects of multiple immune and inflamma

24 iew of HIFs; discusses the range of evidence implicating HIFs in beta cell dysfunction, diabetes path

25 sulin secretion in response to high glucose, implicating Zranb3 in beta-cell functional response to h

26 ged para-hydroxyl substituted bis-styryl-BTD implicated differences in binding site polarity of polym

27 We implicate abnormalities in both frequencies and function

28 mitosis, recent work in interphase cells has implicated the centrosome in both microtubule and actin

29 In summary, our work implicates c-Rel in both CNS-resident cell survival and

30 root vasculature, and shoot apical meristem, implicating it in both local and systemic signaling of S

31 Further investigation of the function of the implicated genes in breast and immune cells may provide

32 Altogether, our results implicate damaging variation in BRSK2 as a source of neu

33 ses that directly act as dynein adaptors and implicate CRACR2a-dynein in calcium-regulated endocytic

34 within skin-specific regulatory elements and implicate loci involved in cancer development, immune re

35 variants disrupting TAD boundaries have been implicated both in cancer and developmental disease; thi

36 nctional analysis of non-CAD-associated loci implicate genes involved in cardiac development (MYOZ1,

37 size, and depressed cardiac function, newly implicating MerTK in cardiac repair after myocardial isc

38 Despite mounting evidence implicating inflammation in cardiovascular diseases, att

39 otential onto trunk neural crest cells, thus implicating new genes in cardiovascular birth defects.

40 tional homeostasis in the nervous system and implicate RQC dysfunction in causing neurodegeneration.

41 Our results implicate alterations in cellular methylation potential

42 Pathway analysis implicates splicing in cellular PRMT5 dependency, and we

43 taining choroidal vasculature and RPE cells, implicating insufficiency in choroidal macrophage functi

44 d pathology, valid over a 1 year time frame, implicating its use in clinical trials.

45 ed genome-wide association study signals and implicate specific eSTRs in complex traits, including he

46 Our findings implicate Asp1 pyrophosphatase in constraining 1,5-IP8 o

47 These results implicate Ub signaling in coordinating RNA processing by

48 es mitochondrial activity to redox needs and implicates metabolic control in coordination of stress a

49 Studies have implicated WDR92 in coronary artery damage.

50 ent sensing and the DNA damage response, and implicated Vts1 in de novo gene "birth." TGA provided si

51 e introduced super-generalist pollinator are implicated as key in determining the roles introduced sp

52 Some of our findings implicate pathways already in development as drug target

53 a postmortem samples compared with controls, implicating astrocytes in DG, immune mechanisms in CA3,

54 unction and overactive GH signaling has been implicated in proteinuria in diabetes and acromegaly.

55 effects on the secondary aerosol formation, implicating that, in diesel engines, either the lubrican

56 ical rodent studies during the last 20 years implicated glutamate neurotransmission in different brai

57 endelian disease family is not sufficient to implicate a gene in disease etiology.

58 siology of Parkinson's disease (PD) strongly implicate mitochondria in disease aetiology.

59 xpression and functional studies, can aid in implicating a gene in disease etiology.

60 t mutation hotspots in human cancer genomes, implicating them in disease etiology.

61 Using functional assays, we now implicate different miRNAs in distinct phenotypes: miR-1

62 Recent studies have implicated changes in DNA methylation and small RNAs in

63 association study of Huntington disease (HD) implicated genes involved in DNA maintenance processes a

64 Thus, our studies implicate NELF functioning in early elongation complexes

65 Based on these findings, we securely implicate PPP3CA in early-onset refractory epilepsy and

66 rent reality, an increasing body of evidence implicates perturbations in early development that alter

67 In vitro studies implicate BRCA1 in elimination of R-loops, DNA-RNA hybri

68 Overall, the findings implicate the IFC in emotion processing and demonstrate

69 ishes nonrandom inhibitory connectivity, and implicates this patterning in encoding specific features

70 In vitro evidence implicates BIN1 in endosomal sorting of BACE1 and Abeta

71 Our findings offer causal evidence implicating the PCC in episodic memory encoding.

72 ive for the apoptotic suppressor ced-9/Bcl-2 implicating SEP-1 in execution of apoptosis.

73 Previous studies have implicated changes in expression and subcellular localiz

74 Based on previous studies implicating changes in extracellular matrix remodeling i

75 s have helped to illuminate a mechanism that implicates vascular biology in eye disease.

76 armacological administration of oxytocin has implicated this neuropeptide in face perception and soci

77 We implicate novel genes in fat distribution, stressing the

78 eral GSLs are higher in the suppressor line, implicating FSH in feedback control of GSL flux.

79 Conceptualizations of delusion formation implicate deficits in feedforward information updating a

80 g virtual reality and mediation analysis, we implicate shifts in FOV as a mechanism linking symptoms

81 pramarginal gyri, which have previously been implicated in autism in functional MR imaging studies.

82 ay transcriptional coactivators YAP/TAZ were implicated as drivers in GBM progression and could be th

83 gration 1 (Fli-1) signaling network has been implicated in oncogenesis in GBM, making it an appealing

84 lently closed structure, high stability, and implicated roles in gene regulation.

85 These results implicate additional mechanisms in generating directiona

86 ditis elegans and in chondrogenic cell lines implicated variants in genes necessary for transcription

87 st a placental component to the aetiology by implicating common variants in genes encoding placental

88 or outcome has been linked to MYH6 variants, implicating overlap in genetic etiologies of structural

89 A growing number of studies implicate alterations in glutamatergic signaling within

90 Previous reports and our current data implicate DDIT4/IFRD1 in governing paligenosis in multip

91 Together, our data implicate SHP in governing ER homeostasis and identify a

92 Results strongly implicate opioids in gregarious song and suggest that en

93 activity in the parabrachial nucleus (PbN), implicated for roles in gustation and pain.

94 Metabonomic studies implicated variations in gut microbial activities that m

95 Our results implicate localized charge in HA interactions with host

96 aging of these disorders and rodent modeling implicate dysregulation in hippocampal glutamate and the

97 The top signal resided in GREB1L, a gene implicated previously in Hoxb1 and Shha signaling in zeb

98 In sum, our efforts implicate CARS variants in human inherited disease, expa

99 plexity of PIK3CD regulation in human brain, implicate PIK3CD in human neurodevelopment, and identify

100 s/differences of sex development (DSD), also implicate this gene in human testis determination.

101 Findings from the past decade that implicate autoimmunity in IBM include the identification

102 an promote effective anti-tumor immunity and implicate PTPN2 in immune cells as an attractive cancer

103 Recent research has implicated economic insecurity in increasing midlife dea

104 They are discussed in terms of a hypothesis implicating Epac actions in increasing RyR-mediated SR C

105 ratio in ilea from Msi1-overexpressing mice implicated Notch signaling in inducing enterocyte differ

106 Recent studies have implicated SAAs in innate immunity and various disorders

107 nterneuron number and mitotic delay, further implicating mitotic defects in interneuron loss.

108 ptor MRGPRX1 and the mouse homolog MrgprC11, implicated previously in itch.

109 is and structural modeling analyses directly implicated N-glycans in Klotho's protein folding and fun

110 ynuclein (alphaS), which is both genetically implicated and accumulates in Lewy bodies rich in vesicl

111 oxidative stress, and sleep-three processes implicated independently in lifespan, ageing, and degene

112 with molecular and animal behavioral studies implicating Apba2 in locomotion.

113 etacean liver under hypoxic conditions, thus implicating FGF23 in low bone density in cetaceans.

114 monocytogenes uses EVs for toxin release and implicate these structures in mammalian cytotoxicity.

115 across the cytoplasmic membrane and has been implicated in virulence in many bacterial pathogens.

116 diverse cellular and developmental pathways, implicating them in many diseases besides cancer, includ

117 Finally, we present data implicating Prosapip1 in mechanisms underlying alcohol s

118 nk the molecular and cellular phenotypes and implicate alterations in mechanosensing as an important

119 function in soil microbial communities, and implicate compositional shifts in mediating biogeochemic

120 minal four-helix bundle (4HB) domain of ExoU implicated previously in membrane binding.

121 r findings provide the first causal evidence implicating PCC in memory encoding and highlight the PCC

122 eted fat reserves, and developmental delays, implicating IMD in metabolic regulation.

123 ERK7 has been recently implicated in ciliogenesis in metazoan cells, and our da

124 Research has also implicated cystinosin in modulating the mTORC1 pathway,

125 of tumor-associated USP22 overexpression and implicate USP22 in modulation of cellular survival and D

126 Previous studies in human cell lines have implicated altered DDX6 in molecular and cellular dysfun

127 Together, this work implicates Msi1 in mouse postnatal development of multip

128 wn to be deficient in MSA brain tissue, thus implicating mitochondrial dysfunction in MSA.

129 Environmental and hormonal factors are implicated in dysimmunity in multiple sclerosis.

130 ough WNT signaling and calcineurin have been implicated separately in muscle remodeling, we unexpecte

131 ST2 axis in bronchial epithelial repair, and implicate ST2 in myeloid cell differentiation.

132 in the context of recent preclinical trials implicating ACLY in NAFLD progression.

133 Prior studies implicate abnormal ECM in NCC migration failure.

134 aptation across the latitudinal gradient and implicate genes involved in nervous system function.

135 It is among the most commonly implicated factors in neurodevelopmental autism spectrum

136 Each element of the loop has been implicated previously in neuropsychiatric disease.

137 However, the majority of GWAS-implicated variants are in non-coding regions of the gen

138 These observations implicate macrophages in normal and aberrant cardiac con

139 Our findings implicate Cdc42 in nuclear envelope sealing and ER remod

140 Our findings implicate epigenetic mechanisms in OD and, if replicated

141 These results implicate disruptions in OL biology as a cellular mechan

142 Recent data also implicate sex differences in opioid metabolism and neuro

143 ramifications of the Hechtian oscillator may implicate AGPs in osmosensing or gravisensing and other

144 Although accumulating evidence has implicated BMPs in osteoblastogenesis, the mechanisms by

145 ions in several gene families that have been implicated in parasitism in other nematode species.

146 ni serves as a reservoir of Helicobacter and implicate Helicobacter in pathogenesis of opisthorchiasi

147 IR is implicated both in pathogenesis of NAFLD and in disease

148 binding pockets of the HLA class II molecule implicates antigen presentation in PD pathogenesis and p

149 eral rostrolateral prefrontal cortex (BA10), implicated more generally in planning of complex goal-di

150 Basic research has implicated dopaminergic signalling in plasticity.

151 While hydrophobicity analysis implicated self-peptides in positive selection of the ov

152 ses focused on the VMPFC, following research implicating this region in positive evaluations based on

153 with class I HLA variants are novel as they implicate adaptive immunity in post-traumatic sepsis.

154 n hormones regulate delta-GABA(A)Rs, further implicating these receptors in potential sex differences

155 crease in the absence of Clp1 activity, thus implicating Clp1 in promoter directionality.

156 Substrate utilization studies additionally implicate mTORC2 in promoting acetyl-CoA synthesis from

157 of cardiac pacemaker cells in zebrafish and implicate Wnt5b in promoting their differentiation.

158 gnancy with a dismal posttreatment prognosis-implicate XBP1s in promoting tumor vascularization and p

159 rate therapeutic T-cell products for ACT and implicates IL6 in promoting durable immunity of Th17 cel

160 d antitumoral responses, but recent evidence implicates them in promoting carcinogenesis in certain c

161 These findings implicate LCE proteins in psoriasis pathogenesis via a n

162 Accumulating evidence implicates inflammation in pulmonary arterial hypertensi

163 uded: the detection of NMNAT2 mutations that implicate Wallerian degeneration in rare human diseases;

164 nscriptomic and mass spectrometry approaches implicate RABL3 in RAS pathway regulation and identify a

165 Collectively, these results implicate NAc D2R in regulating both peripheral glucose

166 Recent discoveries further implicate SSPs in regulating root nodule development, wh

167 Together this implicates UBR5 in regulating TTC7A signaling in VEOIBD

168 NTP synthesizing enzymes RRM2, TYMS and TK1, implicating lincNMR in regulating nucleotide metabolism.

169 of non-miRNA dependent functions as well as implicating RNA in regulating DNMT1 activity and correct

170 Prior rodent studies have implicated these regions in regulation of punished EtOH

171 ption factor -2 ( SNAI2) (also called SLUG), implicating LGR4 in regulation of epithelial-mesenchymal

172 ciated with actively transcribed DDIT4 loci, implicating these bodies in regulation of basal DDIT4 ex

173 Our findings implicate NET formation in rendering the premetastatic o

174 poly(A)-binding proteins has previously been implicated only in repression of Musashi target mRNAs, o

175 This finding is the first to implicate this circuit in rodent socioemotional behavior

176 transferase-family protein with a previously implicated role in SA accumulation upon pathogen attack,

177 ked kinase and IL-8 signaling and previously implicated pathways in sarcoidosis, including phagosome

178 hippocampus are consistent with models that implicate synaptic loss in schizophrenia.

179 In light of the clinical evidence implicating dopamine in schizophrenia and the prominent

180 in treatment resistant chronic SCZ patients, implicating NDEL1 activity in SCZ.

181 Mounting evidence implicates PAR in seeding the abnormal localization and

182 e most pro-excitatory physiological changes, implicating this population in seizure generation or pro

183 Although studies have implicated SYNGAP1 in several cognitive disorders, it is

184 Our results implicate defective autophagy in SHRF pathogenesis and s

185 rapidly activated during SI; several studies implicated its role in signaling to SI-induced programme

186 THEMIS during thymocyte positive selection, implicating THEMIS in signaling downstream of the T cell

187 ations using density functional theory (DFT) implicate the in situ formation of a rapidly equilibrati

188 itation of SIV-specific humoral immunity and implicate their participation in SIV control.

189 xome sequencing, we identify RRAS2 as a gene implicated in NS in six unrelated subjects/families.

190 These data implicate replication in skeletal muscle cells and relea

191 Functional annotation of these three signals implicated processes in skeletal muscle, subcutaneous ad

192 We implicate vHIP-NAc in social interaction and anxiety-lik

193 tions correlates with the speed of movement, implicating these signals in spatial navigation.

194 Together, these findings implicate PREX1 in spontaneous bone dissemination and pr

195 aches enable new avenues of exploration that implicate causal genes in sporadic late-onset Alzheimer'

196 type, with CXCR5/Bcl-6 and IL-21 expression, implicating a role in stimulation of pathogenic autoanti

197 ed neuromodulatory system within the NAc and implicate HA in stress-associated physiological states.

198 nce, accelerate aging, and shorten lifespan, implicating chromosome architecture in stress responses

199 ically-committed CD271+CD56+ BMSC subset and implicates it in subchondral bone sclerosis in hip OA.

200 ectivity account (Yazar et al., 2012), which implicates AnG involvement in subjective mnemonic experi

201 results in a 2- to 3-year immunomodulation, implicating measles in substantially more child mortalit

202 structures, and mutagenesis experiments, we implicate specific residues in substrate positioning and

203 Together, our results implicate Rac1 hyperactivity in synaptic plasticity and

204 auditory and vestibular organs on E8-E10 may implicate Sema signaling in synaptogenesis.

205 dren in these families, and provide evidence implicating other genes in syndromic CS.

206 These findings implicate MARKs early in synucleinopathy pathogenesis an

207 Together, these findings implicate proteasome dysfunction in SZ, which likely has

208 These data implicate FcRn in TF-dependent FXa activity induced by s

209 Overall, our findings implicate aberrant SINGD in the pathogenesis of diabetes

210 Such findings strongly implicate Abeta in the altered iron handling and increas

211 Thalamus models of psychosis implicate association nuclei in the pathogenesis of psyc

212 These findings implicate CA19-9 in the etiology of pancreatitis and pan

213 Research findings implicate cerebral glutamate in the pathophysiology of s

214 These results implicate CFTR activation in the colon as a major prosec

215 Multiple lines of evidence implicate chromatin in the regulation of premessenger RN

216 Collectively, our genome-wide analyses implicate condensin in the suppression of hundreds of lo

217 idence from preclinical and clinical studies implicate dopamine hypofunction in the pathophysiology o

218 Taken together, these studies implicate Gal-9 in the regulation of cellular proliferat

219 GSTO1 as a therapeutic target in cancer and implicate GSTO1 in the modulation of tumor growth, immun

220 efine the primary aldosteronism syndrome and implicate it in the pathogenesis of "essential" hyperten

221 These results implicate LRRTM4 in the GPR179-pikachurin-dystroglycan t

222 Our results implicate lysosomal dysfunction in the pathogenesis of c

223 These results implicate MAIT cells in the protection against pneumococ

224 Our findings implicate miRNAs in the eutherians' increase in neuronal

225 These findings implicate PMd in the action-selection but not the percep

226 Recent investigations implicate pyroptosis in the pathogenesis of multiple neu

227 ary genetic and structural analyses in yeast implicate these alleles in the stability of the spliceos

228 tors for ASD, and human iPSC-derived neurons implicate these deletions in the neurophysiology of exci

229 Our findings also implicate this circuitry in the formation of complex spa

230 Genomic studies implicate this locus in the initiation of clinically sig

231 or adrenocortical aldosterone production and implicate this pathway in the determination of zone-spec

232 Our findings also implicate TrkB signaling in the complex pathology of TSC

233 Together, these data implicate trkB signaling in the symptomatic efficacy and

234 Here, we implicate Wnt signaling in the pathoetiology of PDL resp

235 A recent study implicated activity in the human hippocampus with holist

236 Based on work that implicated ASIC1A in the amygdala and bed nucleus of the

237 Numerous studies have implicated changes in the Y chromosome in male cancers,

238 Newly implicated genes identified in the eQTL analysis include

239 A number of studies have implicated glycosyltransferases in the pathogenesis of n

240 r acetylation and protein expression studies implicated HDAC3 in the regulation of multiple regenerat

241 Mass spectrometry-based phosphoproteomics implicated HDAC8 in the regulation of MAPK and AP-1 sign

242 NOD2 is implicated in changes in the composition of the intestin

243 While some studies have implicated Lewy bodies in the neocortex, others have poi

244 ying pain-comorbid NA, previous studies have implicated neuroinflammation in the pathophysiology of b

245 Studies of visual attention have implicated oscillatory activity in the recognition, prot

246 Tissue-enrichment analysis implicated the CNS in the aetiology of handedness.

247 ants and that its retention therein strongly implicates ABA in the regulation of their relevant tropi

248 Preclinical evidence implicates cholinergic neurotransmission in the function

249 Overall, this study implicates complement in the immune landscape of renal c

250 wing body of evidence from the past 15 years implicates epigenetic mechanisms in the behavioral effec

251 Increasing evidence implicates immune dysregulation in the development of ne

252 This study implicates microRNAs in the pathogenesis of AA.

253 dy of CNVs affecting barley gene content and implicates SDs in the molecular mechanisms that lead to

254 The predominance of H-DNA implicates this structure in the instability associated

255 ro, while next generation sequencing broadly implicates TrkB.T1 in the PI3K signaling cascades in a l

256 date in the general European population and implicates vitamin D in the etiology of multiple scleros

257 Evidence implicates YAP in the control of cellular nutrient and e

258 d CFR in men and women with type 2 diabetes, implicating aldosterone in the pathophysiology of corona

259 n addition, although we do not find evidence implicating altered proliferation in the rescue, we obse

260 tocellular carcinoma (HCC) development, thus implicating ATX/LPA in the causative link of cirrhosis a

261 deleting the fetal globin repressor BCL11A, implicating BCL11A in the function of the HBBP1 region.

262 une cell subsets pivotal to these responses, implicating CD14(+) monocytes in the cholinergic inflamm

263 ances including hippocampal memory deficits, implicating CD44 in the processes underlying hippocampal

264 -binding factor impaired nerve regeneration, implicating chromatin organization in the regenerative c

265 This article reviews emerging evidence implicating different septins in the regulation of host-

266 Herein, the evidence implicating epigenetics in the pathogenesis of SSc is di

267 Unlike previous observations implicating flavonoids in the resistance of transgenic s

268 ation and provide the first imaging evidence implicating inflammation in the pathophysiology of migra

269 Yet, direct evidence causally implicating inhibitory signaling in the dynamics of bino

270 There is compelling evidence implicating intestinal permeability in the pathogenesis

271 ptor signaling abrogated induction of MCP-1, implicating it in the antitumor effects of IgE.

272 a striking absence of primary neurogenesis, implicating n1-src in the specification of neurons early

273 variants (SVs) affecting non-coding regions, implicating recurrent deletions in the promoters of DLG2

274 rize the strengths and weaknesses of studies implicating selected variants in the pathophysiology of

275 ates with KIF3A, KIF5B, KIF1A, and dynactin, implicating spectrin in the coupling of motors and synap

276 nt in athymic Nu/Nu and lymphodepleted mice, implicating T-cells in the acidifying process.

277 Mechanistically, we present evidence implicating the BBSome in the trafficking of G protein-c

278 d adenosine triphosphatase and Rca activity, implicating them in the Rubisco interaction.

279 s are present in several commensal bacteria, implicating these genes in the degradation of dietary gl

280 ependent on MSB2 for its expression, thereby implicating these genes in the process of filamentation.

281 which was reduced by the R289A substitution, implicating this interaction in the observed processing

282 de changes in the cholinergic pathway genes, implicating this miR in the avoidance of seizures.

283 Neuroimaging studies in humans have implicated insular cortex in these phenomena.

284 In this Review, we outline the evidence implicating necroptosis in these neurological diseases a

285 systemic spread was enhanced in NahG plants, implicating SA in these processes.

286 t exacerbated L-ala,SP + amiodarone effects, implicating the prodrugs in these effects.

287 ulate normal reproductive function, strongly implicating their role in these adaptations.

288 ate that A34 is involved in cell binding and implicate the ectodomain in this role.

289 ss only in females during scheduled fasting, implicating metabolic mechanisms in this sexually dimorp

290 Positional analysis of lincRNA loci implicated involvement in transcriptional regulation.

291 cysteine-deprivation-induced ferroptosis and implicates ferroptosis in tumor suppression.

292 types, as well as a few specific mechanisms implicating individual sites in tumorigenesis or metasta

293 ition shunts the kynurenine pathway-which is implicated as dysfunctional in various psychiatric disor

294 Numerous studies have emerged implicating Dkk1 in various malignancies and neurodegene

295 s an attractive technique to test hypotheses implicating telomere length in various cardiac pathologi

296 e additionally survey the growing literature implicating these proteins in various neurological disor

297 ears, largely due to recent genetic findings implicating microglia in virtually every neurodegenerati

298 Phospholipase C gamma 1 (Plcgamma1) has been implicated for hematopoiesis in vivo and in vitro and is

299 esults are consistent with emerging evidence implicating PPC dysfunction in WM impairment and suggest

300 Our observations implicate disruption in ZnT2 function as a modifier of s