ライフサイエンスコーパス: implication

1 ion of extracellular matrix - have metabolic implications.

2 en and children have important public health implications.

3 n, and neuroinflammation, and on therapeutic implications.

4 cells, which may have potential therapeutic implications.

5 static pattern in CRC and has great clinical implications.

6 variants in this locus, and their potential implications.

7 bution, with ecological, economic and social implications.

8 hepatitis, both management and public health implications.

9 osure concentrations and their toxicological implications.

10 lly cereals, can have important agricultural implications.

11 has clear scientific importance and societal implications.

12 ltered in patients' gliomas, with prognostic implications.

13 enetic state has vast medical and biological implications.

14 in order to better predict their functional implications.

15 despite important diagnostic and management implications.

16 nited States, with significant public health implications.

17 age and execution with potential therapeutic implications.

18 vide a detailed workflow to illustrate their implications and additional prerequisites when applied o

19 om clinical trials, and highlight procedural implications and caveats of new and future indications.

20 Implications and potential avenues for future research a

21 on these findings, we discuss the practical implications and suggestions for future studies.

22 ario's resource recovery potential, economic implications, and environmental impacts.

23 vement of neutrophils and NETs, to weigh the implications, and to increase efficiency in clinical tri

24 S mutations and the tissue-specific clinical implications are complex and nuanced.

25 ht (MW) of beta-glucan, the resulting health implications are currently unclear.

26 This has important implications as these structures are predominately consi

27 These findings have important clinical implications as VO2 peak is highly predictive of morbidi

28 Our findings should have implications beyond the capture of lignin-utilizing bact

29 ement tools and their potential evolutionary implications-both their opportunities for and potential

30 n groundbreaking science with major societal implications, communicating about science is critical.

31 s but that may have profound neuroscientific implications: deep reinforcement learning (RL).

32 s with considerably different biogeochemical implications: demethylation channels sulfur into the mic

33 analysis of their ethical, legal, and social implications (ELSI).

34 ations for this conclusion hold a remarkable implication for erasing racial disparity in PCa.

35 However, the precise quantities and the implication for the elicitation of anaphylaxis remains t

36 Implications for a neural common currency of information

37 and their biofilm propensity, has important implications for AD.

38 This has important implications for analytical methods based on extraction

39 Our work has broad implications for anti-Alzheimer's research and drug deve

40 ase its neuroprotective functions, which has implications for anti-parkinsonian therapy.

41 This result has implications for antibody recognition of MPER prior to a

42 geneity of intralesional drug PK, have major implications for antimicrobial drug development.

43 units and on specific shifts, with possible implications for aspects of service design, and high rat

44 social behavior, with potential far-reaching implications for behavioral epigenetics.

45 This may have relevant implications for benchmarking processes and quality impl

46 oteins for lysosomal degradation, with broad implications for biochemical research and for therapeuti

47 s of ducks in nature, our results have major implications for biodiversity conservation and invasion

48 gulates metabolic mechanisms in B cells with implications for bioenergetic and metabolic pathways tha

49 I also discuss implications for biosignatures and technosignatures.

50 weather has variable and potentially strong implications for birds at different time scales, but the

51 ractions, PSA-binding ligands have important implications for both biological processes and biotechno

52 ity of blood culture for enteric fever, with implications for both clinical care and surveillance.

53 Our observations have implications for both fork restart and the division of l

54 Together, these findings present novel implications for both future scientific investigations a

55 ffects of non-nitrate components of BRJ have implications for both interpretation of previous finding

56 These motifs are highly specific with implications for both signal processing within the retin

57 These results have strong implications for Brain Machine Interface applications an

58 Our results have important implications for cancer biology because oxidized purines

59 These findings could have broad clinical implications for cancer patients.

60 ethnicity of the human host, which may have implications for carcinogenicity.

61 nt in ferrocenyl mixed-valent compounds, and implications for catalysis as well as electronic communi

62 ated infections and diseases, with important implications for childhood mortality particularly in low

63 il formation, with insights that have direct implications for deducing the molecular progression of n

64 n of mutations with aging/maturation and has implications for delayed reproduction in modern human so

65 a DNA repair protein for efficient NHEJ with implications for development of resistance to cancer the

66 these animals changed during growth and has implications for ecology and skull development that go b

67 ons of dietary diversity suggest contrasting implications for efforts to predict how consumers will r

68 This process has important implications for embrittlement and subsequent degradatio

69 ive molecular crystals can have far-reaching implications for emerging fields such as smart microelec

70 c homogenization, our results have important implications for fisheries managers weighing the costs/b

71 Our results have important implications for forecasting mangrove carbon dynamics an

72 nitoring of adherence and (e) discussing any implications for further education and work.

73 rodevelopmental trajectories in TS and carry implications for future applications aimed at predicting

74 states reveal a dynamic tunnel lining, with implications for gating or substrate translocation.

75 ience understanding of status perception and implications for gender- and status-based impression for

76 ntenance and function of the nucleolus, with implications for gene regulation and ribonucleoprotein p

77 e and effectiveness of HR sub-pathways, with implications for genome instability and cancer.

78 The results have wide-ranging implications for global ecology and for anticipating cha

79 These results have general implications for governing global good or bad commons.

80 ider carbohydrates, this study has important implications for how ecologists consider nutrient limita

81 V E7 impairs differentiation has significant implications for HPV-mediated carcinogenesis and the HPV

82 es various toxicities in mice with important implications for humans.

83 These findings have significant and broader implications for immunity and vaccine development agains

84 iomarkers of near-term pregnancy would carry implications for improved monitoring of the annual fecun

85 standing how this decision is made has major implications for improving cancer treatments, particular

86 opulation in China, which may have important implications for improving mental wellness among the pub

87 apid mass loss to the ocean would have clear implications for increasing the rate of global sea level

88 sample a range of conformational space, with implications for maintaining virion stability and infect

89 dependent epizootic population control, have implications for managing lionfish and impacted native s

90 hallenge, but such information has important implications for microbially enhanced energy recovery.

91 These results have important implications for modeling SOA formation and growth in th

92 The answer has profound implications for molecular evolution and our ability to

93 m of acquired MEKi resistance, with clinical implications for MPNST patients harboring NF1 alteration

94 onal centrality measures and has significant implications for network-based interventions.

95 This finding, with deep implications for neuroscience and theory of neural netwo

96 Their competition has great implications for nitrogen loss, conservation, and greenh

97 nes to hydroperoxy amides may have important implications for nucleation and growth of atmospheric se

98 Gaps were identified in the literature for implications for nursing practice and the nursing workfo

99 Our results have wide-ranging implications for optimising antitrypanosomal drugs and a

100 Our findings could have wider implications for other actin-bundling proteins that cont

101 r SAB assay calibration and have significant implications for our understanding of discordance in pre

102 in somatosensory cortex, which has important implications for our understanding of information proces

103 This has important implications for our understanding of the evolution of v

104 mal human tissues, and here we discuss their implications for our understanding of tumorigenesis.

105 Increasing iodine emissions have implications for ozone radiative forcing and possibly ne

106 xtragalactic jets is currently unknown, with implications for particle acceleration, jet formation, j

107 int the hierarchy of T cell clone sizes with implications for pathogen defense and autoimmunity.

108 ed pathological staging systems and may have implications for patient stratification in future clinic

109 The implications for patients with premorbid low/high blood

110 to methylation variability in mammals, with implications for phenotypic variation and putative parad

111 y threatened by climate change with seasonal implications for photosynthesis and forest growth.

112 Implications for policy and research are relevant beyond

113 They also may have important implications for prebiotic chemistry.

114 lation in the JE and have potential clinical implications for prevention and treatment of periodontit

115 nced the composition of available prey, with implications for prey selection, demonstrating how human

116 by modulating the cellular environment, with implications for protein design and combatting antibioti

117 s house a GABA signaling pathway with direct implications for psychiatric disease origin.

118 cation in the aerobiome could have important implications for public health and for the design, engin

119 The implications for public health are twofold, as these pro

120 Chronic pruritus (CP) has considerable implications for QOL.

121 umentation accuracy and utility and may have implications for quality of care and patient-provider re

122 These findings have implications for rational protein design and synthetic b

123 stem cells (iPSCs) would have broad reaching implications for regenerative medicine.

124 This outcome has important implications for risk assessment and the migratory succe

125 -driven structural perturbation of CaM, with implications for RyR regulation and the decay of muscle

126 nst aging-induced atrophy, our findings have implications for sarcopenia.

127 c mechanism with etiological and therapeutic implications for schizophrenia.

128 les such as amino acids, which has important implications for SIMS imaging of metabolites and pharmac

129 memory breaks down and may have considerable implications for stress-related psychopathologies, such

130 These findings may have important implications for studies of coronavirus-induced disease.

131 trumentation and technique advancements have implications for surgeon workload and human-systems inte

132 ns, particularly in Western cohorts, despite implications for surveillance, prognosis, and treatment.

133 and high-latitude ecosystems, with important implications for survival and distribution of species th

134 G12D tumors by immunotherapy and has general implications for T cell-based immunotherapies.

135 tween the expanded Htt allele and Hdac2 with implications for targeting transcriptional dysregulation

136 These findings have significant implications for the application of genome editing in bo

137 Rapid climate change has wide-ranging implications for the Arctic region, including sea ice lo

138 c and unpredictable manner; this finding has implications for the assessment of cavitation resistance

139 plication in the upper respiratory tract has implications for the containment of COVID-19.

140 Further, the results reported here have implications for the design of beta sheet proteins with

141 This has implications for the design of new long-residence-time T

142 0 and CD70 signaling in cDC1s and have major implications for the design of new vaccination strategie

143 This could have important implications for the development and application of both

144 derstanding of tuberculosis control and have implications for the development of both therapeutic and

145 ) memory T cell pool, with potentially broad implications for the development of immunotherapies and

146 t and depression among psychiatrists and has implications for the development of targeted interventio

147 tigen recognition by TCRs and have important implications for the development of TCR-based therapies.

148 inflammatory diseases is anticipated to have implications for the development of treatments that targ

149 for the Pliensbachian and Sinemurian, giving implications for the duration of the Hettangian Stage.

150 For each scenario, we discuss its implications for the dynamics of herd immunity and on pr

151 ological culture but it fails to discuss the implications for the emergence of cumulative cultural ev

152 th stable coronary heart disease and discuss implications for the evaluation of patients with stable

153 Such findings have major implications for the final production of a clinical HIV

154 ging behaviour and cognition, which may have implications for the future protection of pangolin habit

155 radients of climate and biogeochemistry with implications for the geography of plant-consumer interac

156 mmunologic response, and has direct clinical implications for the management and follow-up of patient

157 Our findings have implications for the management of neurological disorder

158 Our findings have serious implications for the management of PCB contamination in

159 These findings have implications for the molecular and cellular mechanisms o

160 These findings have implications for the need of continued protective measur

161 Our data have implications for the organizing principles that govern a

162 and changes to anti-predator behavior, with implications for the outcome of ecological interactions

163 stal growth during amelogenesis, and hint at implications for the preservation of biomarkers during t

164 Our findings may have relevant implications for the prevention and management of CTEPH.

165 The implications for the proposed use of mackinawite as a sc

166 These findings may have implications for the regulation of ghrelin function in v

167 These results have implications for the safe and effective production of no

168 nt-elicited cellular immunity and have clear implications for the screening and evaluation of novel a

169 ning of an oscillatory circuit and has broad implications for the spatiotemporal regulation of signal

170 cocorticoids in eosinophilic disorders, with implications for the study of glucocorticoid resistance

171 These results have profound implications for the study of this key GTPase in cancer,

172 attenuated virus vaccines and have important implications for the success of next-generation OPV.

173 to the Earth's upper mantle, with important implications for the transport of carbon in aqueous flui

174 t in all crystallin proteins, with potential implications for the understanding of crowding effects i

175 gassing of planetary interiors has important implications for their corresponding atmospheres.

176 nts require specialised life-long care, with implications for their families.

177 ow transcription of these repeats occurs has implications for therapeutics in multiple diseases.

178 signature of positive selection and may have implications for tissue or cell-specific expression of t

179 c competence of faster-living hosts also has implications for trade-offs between pathogen virulence a

180 tabolic subphenotype in women with RCC, with implications for tumor progression and outcomes in CRC p

181 component of tumor metabolism, with profound implications for tumorigenesis and treatment response.

182 nction of terminal web myosin and hold broad implications for understanding apical morphogenesis in d

183 mutations in silico is a challenge that has implications for understanding diseases as well as indus

184 This study has implications for understanding how GBA1 mutations influe

185 old mouse HSCs and progenitors, with broader implications for understanding mechanisms for stem cell

186 HSV infection of DRG neurons, which may have implications for understanding of the mechanisms of viru

187 roles of these enzymes, these findings have implications for understanding physiological and patholo

188 ding B cell biology, but also have important implications for understanding tetraspanin function gene

189 more complex than currently recognized, with implications for understanding the character evolution i

190 These results have implications for understanding the etiology and treatmen

191 d in vivo, and thus this work has widespread implications for understanding the mechanisms that regul

192 on with an aversive stimulus, with potential implications for understanding the neural basis of traum

193 of somatic cell populations and discuss the implications for understanding the origins of senescence

194 nt role in inhibitory feedback, and may have implications for understanding the relative contribution

195 These findings have implications for understanding the role of the tumor mic

196 syncratic cortical topographies, and discuss implications for understanding the structure of cortical

197 These findings have significant implications for understanding why a hypomorphic loss of

198 nagement in the recent past, there are great implications for using nanotechnology in immuno-oncology

199 tective immunity, which could have important implications for vaccine development against flagellated

200 ture viral threats, also mentioning possible implications for vaccine development.

201 nts, leading to geographically heterogeneous implications for Wood Frogs.

202 These events have many astrophysical implications; for example, they may lead to the creation

203 associated life-changing health and resource implications have led to a need to improve its early det

204 However, its regulatory implications have not been examined.

205 pression signature was built to assess their implication in neuroblastoma.

206 nscriptional profile of sputum cells and its implication in the pathogenesis of immune function and t

207 n stem cell lineage commitment that may have implications in aging and cancer.

208 urable genomic changes in breast tissue with implications in breast carcinogenesis.

209 ness of this approach, as well as the direct implications in clinical management, should be further e

210 This has implications in determining urgency of LT and mortality

211 These studies have implications in furthering our understanding of JAM in c

212 These results have important implications in general understanding of stimuli-trigger

213 ion of CsACD2 as a susceptibility target has implications in genome editing for novel plant resistanc

214 re adult neurogenesis occurs with functional implications in mood control and cognition.

215 confined reprogramming, which has important implications in regenerative medicine.

216 transporting different cargos with potential implications in therapy resistance.

217 ing global-change-related biotic and abiotic implications, including land-atmosphere feedbacks and ca

218 The major implication is that to ensure serviceability of wood and

219 uced pulmonary congestion carries prognostic implications is unknown.

220 Those implications lead us to move beyond meme-centered or an

221 the survival of gastric epithelial cells has implications not only for H. pylori pathogenesis but for

222 This finding has implications not only for our understanding of basic mec

223 These findings have implications not only for the evolutionary origins of SS

224 We investigated the implication of beta4*nAChRs in anxiety-, food reward- an

225 rformed a clinical study to elaborate on the implication of CTRPs (CTRP1, CTRP5, CTRP7, and CTRP15) i

226 While the implication of cytoplasmic transport in d-Ser toxicity w

227 with type 2 diabetes (T2DM), we revealed the implication of LXR and Nox4 in the pathophysiology of DP

228 The implication of microscopic ileitis finding in patients r

229 tem development and function and support the implication of SCAF4 in neurodevelopmental phenotypes.

230 Considering the demonstrated implication of the retina in Parkinson disease (PD) path

231 To validate the implication of these genes into A. thaliana growth, six

232 A major implication of this study is that the dominance of DNRA

233 he rapidly expanding knowledge regarding the implications of 11-oxyandrogens in human physiology and

234 nd impact on global N cycling processes with implications of a positive feedback to global climate an

235 iagnosis and risk prediction, and prognostic implications of AF and its complications.

236 rovides the first insight into the potential implications of body size and the use of ISS-like CM exe

237 Conversely, many of the concerning health implications of cannabis include cardiovascular diseases

238 We focus on the implications of contract farming for household income an

239 ilitators in addressing these needs; and the implications of existing health policies relating to for

240 y vs sensitivity by considering the clinical implications of false-positive and false-negative result

241 to use CMR to assess independent prognostic implications of functional TR.

242 y further establishes the important clinical implications of genetic and epigenetic ITH in LUAD.

243 t disease, but the prevalence and prognostic implications of hepatorenal dysfunction are unknown in t

244 his requires a detailed understanding of the implications of increased nitrogen demand to store organ

245 uss the important ethical, legal, and social implications of increasing ancestral diversity in geneti

246 These results highlight implications of MOT allocation prioritization, and poten

247 nd highlights the potential, challenges, and implications of natural language processing techniques.

248 We discuss the implications of our findings for how we think about the

249 We discuss the implications of our findings for neural coding and for b

250 The implications of our findings, questioning previous assum

251 ribution, clinical associations and survival implications of PAM immunoreactivity in primary NENs.

252 vian host species, respectively, we test the implications of parasites for annual mortality in wild b

253 Yet, the implications of PSMA PET-derived whole-body tumor volume

254 n an empirical example, we analyzed economic implications of race-based metrics widely used in occupa

255 We focus on the strategic implications of solar geoengineering.

256 deletion in human cancer, but the functional implications of such alterations are not known.

257 The implications of such simplifications should be understoo

258 However, the implications of surviving low-grade ACLF in terms of ris

259 To evaluate the current and future implications of temperature changes for plant phenology,

260 Despite the broad implications of the cannabinoid type 2 receptor (CB2) in

261 The implications of the JTE and PJTE in observable propertie

262 The possible evolutionary implications of the loss of a dedicated olfactory organ

263 The implications of the results are discussed for the develo

264 onship, the inhibitors, and the evolutionary implications of the RSV polymerase.

265 al and atypical circumstances, discusses the implications of the work carried out to date for theory

266 t advocate, to provide their opinions on the implications of these changes in regulatory practices fo

267 However, the implications of these different morphologies for specifi

268 We discuss the implications of these findings for COVID-19 vaccine deve

269 We discuss the implications of these findings for estimates of the impa

270 We explore the implications of these findings for species management an

271 We discuss the implications of these findings in light of emerging role

272 s discussing the mechanistic and therapeutic implications of these findings in the wider context of R

273 Understanding the implications of these findings will be essential for imp

274 We also discuss the implications of these results for translational research

275 We discuss the implications of these results for understanding the mech

276 itional research is needed to understand the implications of these results in explaining the observed

277 -19, the authors also comment on the broader implications of these trials.

278 discusses the goals, methods, challenges and implications of this research endeavour.

279 ge regarding the occurrence and the clinical implications of tick-borne infections in immunosuppresse

280 However, the biological and clinical implications of TP53 allelic state have not been fully i

281 The objective of this study is to assess the implications of using 100 yr and 20 yr static and dynami

282 ons among contributing factors in AD and the implications on disease development and therapeutic inte

283 cture affects local hydrologic response, its implications on global-scale climate remains elusive in

284 vels for e-cigarette users and the potential implications on health outcomes.

285 nce in Pseudomonas species and had important implications on how rhizobacteria sense and respond to i

286 tus of muscle-invasive urothelial cancer has implications on metastatic pattern, metastasis-free surv

287 ion and fluid channelization, with potential implications on seismic activity and transport of deep h

288 ircumpolar 'Divergence Problem', and discuss implications on the terrestrial carbon cycle.

289 LA strain provided additional prognostic implication over clinical information and conventional e

290 rent carbapenemases have differing treatment implications, particularly for new beta-lactam/beta-lact

291 , but also portends consequential behavioral implications: People prefer to allocate strictly "necess

292 silica content, a trait which has important implications ranging from defense to global Si cycling.

293 ostic accuracy, gene fusions have prognostic implications, such as unfavorable prognosis of PAX3-FOXO

294 tion therapy workflow with discussion of the implications that AI is likely to have on each step of t

295 olerances, the model quantifies the negative implications that salts in irrigation water have on soil

296 teract, leading many to wonder what, if any, implications this interactive revolution has had for peo

297 Their findings have important implications to vaccine design.

298 odify their functions, imparting significant implications upon their physiological and therapeutic po

299 ion in the subsurface can have environmental implications when gas components (e.g., methane, longer-

300 s during cambium-driven root growth and have implications with regard to future engineering schemes,