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1 of EGS services is a globally and regionally important issue.
2 hetic dyes in foodstuffs and beverages is an important issue.
3 take characteristics and mobility remains an important issue.
4 aper substitutes, has become an increasingly important issue.
5 he overall quality of iPSC clones will be an important issue.
6 research efforts should seek to resolve this important issue.
7 ce-supporting infrastructures have become an important issue.
8 making the care of potential organ donors an important issue.
9 ts in deaths, therefore, its detection is an important issue.
10 associated with long-term CNI use remains an important issue.
11 ce of misauthenticated cell lines remains an important issue.
12 ation performance and choice of reference an important issue.
13 g pathways that drive Brn-2 expression is an important issue.
14 spitals in Korea, care quality has become an important issue.
15 heterogeneity of the tumor vasculature as an important issue.
16 mation from literature is challenging but an important issue.
17 s and clinical trial designs to address this important issue.
18 efore, the control of liver metastases is an important issue.
19 ween true and false positive CNAs becomes an important issue.
20 ver 90% of patients, but toxicity remains an important issue.
21  genetic disorders is needed to address this important issue.
22  last year and neuroprotection has become an important issue.
23 the persistence of S. aureus is therefore an important issue.
24 going trial in the UK will soon address this important issue.
25 ar risk in the general population remains an important issue.
26  need for international action plans on this important issue.
27 rpinning BRAFi-based therapy is therefore an important issue.
28 -dimensional complex dynamical systems is an important issue.
29 t will shape policy makers' thinking on this important issue.
30  other types of vegetable oils has become an important issue.
31 ther allergic disease is a controversial but important issue.
32 ons in patients with advanced disease remain important issues.
33 reat patients before and after resection are important issues.
34 thesis and the catabolism of CD23 are, thus, important issues.
35 ple dyadic considerations leave out too many important issues.
36 uthors' simulations revealed two potentially important issues.
37  recent studies that shed new light on these important issues.
38 encies in knowledge of many aspects of these important issues, a vaccine for the most important patho
39  our understanding of the condition or raise important issues about its diagnosis and treatment.
40                     Here, we explore several important issues about mechanisms of redundancy, heterog
41 energy will be spent keeping fit this raises important issues about new energetic trade-offs, which h
42 ical rather than Darwinian thinking, raising important issues about the questions that are actually b
43                                           An important issue affecting genome-wide association studie
44 is during chondrogenic differentiation is an important issue affecting the use of stem cells in carti
45 le tumor after the end of therapy remains an important issue and is one of the major applications of
46 is Gem, I review recent data addressing this important issue and propose a testable hypothesis that c
47 field in the past few years have highlighted important issues and at the same time raised new questio
48 utism spectrum disorders (ASDs) to highlight important issues and challenges for the implementation o
49 dress each of these arguments, acknowledging important issues and clarifying some misconceptions, and
50 r the main findings from reports to identify important issues and establish recommendations for futur
51 ly progressing field by highlighting several important issues and parameters, such as the role of dom
52        This Minireview discusses some of the important issues and problems to be solved if these effo
53                                          Two important issues are addressed, including the potential
54              Regarding reporting, especially important issues are the extent to which implementing st
55                                          Two important issues are the retinal safety of cefuroxime an
56                                              Important issues arise with the interpretation of these
57  associated vasculitides and to identify the important issues arisen in the adult literature.
58                                   This is an important issue as such dynamic changes affect exposure
59 ple-related microarray studies has become an important issue as the technology becomes mature and pre
60          Recent studies have focused on such important issues as the use of the Internet in medicine,
61 ue to computed tomography (CT) has become an important issue, as the number of CT examinations has be
62                                    These are important issues, as recombination errors cause cancers
63                                   This is an important issue because incorrectly mapped reads affect
64 en the transport and magnetic topology is an important issue because the structure of magnetic island
65                            We addressed this important issue by uniquely examining the intrinsic func
66 e target, many intuitive yet mechanistically important issues can begin to be addressed.
67             Food security is one of the most important issues challenging the world today.
68                          Our data also raise important issues concerning delayed transgenerational ef
69               Nonetheless, the debate raises important issues concerning the accurate early identific
70                              We discuss some important issues dealing with these topics.
71                                         Many important issues (eg, mechanism(s) of action of stem cel
72                                              Important issues emerging include the organisation of fi
73                         Our method addresses important issues encountered in AP-MS datasets, making R
74                                   To examine important issues encountered in sleep data analysis, we
75 pecific dopaminergic receptor subtypes is an important issue, especially with respect to new drug dev
76 itis C virus, viral resistance has become an important issue, essentially precluding use of protease
77 d rectum after subtotal colectomy remains an important issue even in the era of ileal pouch-anal anas
78  to TRAIL and other targeted therapies is an important issue facing current cancer research field.
79 cation and traceability of craft beers is an important issue for both beer consumers and producers.
80 ormation of ultrafast folding proteins is an important issue for both experiments and simulations.
81 rol of a microarray experiment has become an important issue for both research and regulation.
82                                           An important issue for chromatin remodeling complexes is ho
83  among women 40 to 49 years of age remain an important issue for clinical practice.
84 (OSPW) for return into the environment is an important issue for effective tailings management in Alb
85  may impact sensory reliability, which is an important issue for feedback control because different s
86 lability of lithium is gradually becoming an important issue for further continued use and developmen
87 ms on in vivo experiments continues to be an important issue for mice being used for biomedical resea
88    The quality of the images obtained was an important issue for OCTA, as 15.1% of scans were nongrad
89 se health professionals need to address this important issue for older adults who lose the ability to
90                                     The most important issue for our responders was the handling of u
91 fibre in baked goods and cereal flours is an important issue for research, nutritional labelling and
92              Animal nutrition constitutes an important issue for the animal production industry.
93 en solvents with low toxicity and cost is an important issue for the biochemical industry.
94 e-immobilized ligands or binding sites is an important issue for the development of sensors, array- o
95 omineralization using protein cavities is an important issue for the fabrication of biometamaterials
96            Bread staling reduction is a very important issue for the food industry.
97                                           An important issue for the implementation of silicon is the
98 brain as well as in the peripheral blood, an important issue for the translational approaches of this
99 today, but they do view climate change as an important issue for the world today and for the United S
100                          It is an especially important issue for this class of material because of th
101 ing donor liver transplantation (LDLT) is an important issue for this procedure.
102                              We examined two important issues for accurate promoter prediction: (1) t
103                                          Two important issues for conservation are the range expansio
104                       This presents two very important issues for organic chemists.
105  development (192, 18.3%) are among the most important issues for the respondents.
106                          Such findings raise important issues for therapeutic advances specifically t
107 e highlight meritorious examples that tackle important issues from contemporary organic synthesis, an
108 of these cues has not been fully defined, an important issue given that EMT is an early event in tumo
109 es based on CO2 reduction is an increasingly important issue given the world's continued reliance on
110 nemonic and spatial processing demands, both important issues given approach-avoidance behavior in hu
111                                    These are important issues given the obesity epidemic and the asso
112 results in enhanced cellular specificity, an important issue has recently emerged related to the sele
113                                   One of the important issues has been the outmigration of the develo
114                              To address this important issue, here the cytoskeleton mechanics of BALB
115 all data sets were analyzed in replicate, an important issue ignored by most studies in the past.
116                  IPV is now recognized as an important issue impacting the health of children.
117                                           An important issue in affective neuroscience concerns the r
118                        We further address an important issue in aging research, wherein so far, the k
119 particles through representative soils is an important issue in assessing their mobility and fate in
120 oor adherence to maintenance treatment is an important issue in asthma management, and can partly exp
121 f novel morphological traits is an extremely important issue in biology, and a frequent source of thi
122         Population stratification remains an important issue in case-control studies of disease-marke
123 material instabilities during processing, an important issue in commercial metal alloys.
124 tional foods or nutraceuticals has become an important issue in current health research.
125 utation level variance values have become an important issue in determining the mechanisms that cause
126       Extension of the serum half-life is an important issue in developing new therapeutic proteins a
127 lly expressed in stem/progenitor cells is an important issue in developmental and stem cell biology.
128 Differences in molecular chirality remain an important issue in drug metabolism and pharmacokinetics
129                The authors have addressed an important issue in epidemiology: Often causal effect est
130                                           An important issue in eQTL mapping is how to effectively in
131                       Flavonoid oxidation is important issue in food processing and quality.
132 ous impact on public health, representing an important issue in food science.
133                                           An important issue in food technology is that antimicrobial
134 g genome-wide statistical significance is an important issue in genetic studies.
135        Emerging vector-borne diseases are an important issue in global health.
136                           This emotion is an important issue in intensive care settings because of it
137                              To resolve this important issue in memory representation, we presented m
138                                           An important issue in mercury (Hg) biogeochemistry is to ex
139       Population structure is a particularly important issue in nonhuman species since it is often di
140 ar juvenile idiopathic arthritis (JIA) is an important issue in pediatric rheumatology.
141 osition during wood formation is not only an important issue in plant biology but also critical for p
142 ele in a population is under selection is an important issue in population genetics, and various neut
143                                           An important issue in practical applications is the tendenc
144             Accurate detection of SAPs is an important issue in proteomic analysis at the experimenta
145 d, Safeukui et al have come to grips with an important issue in red blood cell (RBC) biology.1 Their
146  cortical activity and stimulus coding is an important issue in sensory neuroscience.
147    The loss of corticosteroid efficacy is an important issue in severe asthma management and may lead
148 very sleep after prolonged wakefulness is an important issue in sleep research.
149 y transport mechanism of flares, which is an important issue in solar and plasma physics.
150 of the knee to assess joint space loss is an important issue in studies of progression and treatment
151 otion and cognition interact, a specifically important issue in surprise research.
152        Hidden variability is a fundamentally important issue in the context of gene expression studie
153 ar subgroups based on multi-omics data is an important issue in the context of precision medicine.
154 he carbon dioxide capture is a more and more important issue in the design and operation of boilers a
155                Sample size calculation is an important issue in the experimental design of biomedical
156                Epigenetic heritability is an important issue in the field of genetics and also in the
157  ligands present in a cytosolic milieu is an important issue in the field.
158    Rapid detection of bacterial growth is an important issue in the food industry and for medical res
159       Saffron quality characterization is an important issue in the food industry and of interest to
160 ive manner, with each section focusing on an important issue in the literature where we feel that the
161 heir negative predictive value represents an important issue in the management of patients who requir
162 l need to be covered to further clarify this important issue in the management of type 2 diabetes.
163           The Th1/Th2 paradigm has become an important issue in the pathogenesis of asthma, character
164                                           An important issue in the study of cities is defining a met
165                              Furthermore, an important issue in the study of consciousness is the pre
166     Resistance to current drug therapy is an important issue in the treatment of epilepsy.
167 rkers at very low concentrations have become important issues in advanced biological and chemical sen
168 e the application of this unbiased method in important issues in ChIP-Seq data analysis, such as data
169                                    These are important issues in clustering applications, which highl
170                           We further discuss important issues in combining genomics/proteomics databa
171 cies richness is one of the most debated and important issues in ecology.
172 ld in Rome, Italy in June 2019 we identified important issues in existing self-care research.
173 n of cooperative behavior is one of the most important issues in game theory.
174 o a better understanding of some of the most important issues in many-body physics, such as high-temp
175                This work illustrates several important issues in physical activity epidemiology regar
176 lds have considerable promise in elucidating important issues in plant domestication and in agricultu
177                    This work addresses three important issues in protein-protein docking: implementin
178 eoclastogenesis and in bacterial clearance-2 important issues in S. aureus-induced joint destruction.
179 posomes should be useful for addressing many important issues in SNARE-mediated membrane fusion.
180                                              Important issues in stem cell biology, such as stem cell
181 tivated rice, clarifying three ambiguous but important issues in the evolution of wild Oryza species.
182 orms in 1997, IVIVC has been one of the most important issues in the field of pharmaceutics.
183 ort communication first reports detailed and important issues in the use of the mixed discontinuous G
184                                              Important issues include microscale geometry of neural p
185                                              Important issues include multisystem disease associated
186                                              Important issues include new diagnostic thresholds, out-
187                                              Important issues include the relationship between dose a
188 ture systems after catastrophic events is an important issue, inspiring work in multiple fields, incl
189   We apply this methodology to look at three important issues, involving the relationships between re
190                                           An important issue is consumer communication, because consu
191 he need for research further addressing this important issue is highlighted.
192 rils is not clear, and investigation of this important issue is hindered by the unavailability of sta
193                                           An important issue is how cells achieve and regulate effici
194                                           An important issue is how normal brain aging transitions to
195                                           An important issue is how remission and flare are defined a
196                                           An important issue is if the amount of legacy P mobilized f
197                                           An important issue is that the nature and roles of the algo
198 om the diagnosis of the duplication cyst, an important issue is the detection of concomitant developm
199 guidelines or in certain settings; thus, the important issue is the management of COIs in a fair, jud
200                                           An important issue is understanding how the hippocampal pla
201                                     The most important issue is what results generated by these assay
202                                     The more important issue is whether increasing blood [GDF11] repa
203                                           An important issue is whether rodent models are predictive
204                                           An important issue is whether Weyl physics appears in a bro
205  Raman scattering (SERS) sensors, one of the important issues is the development of substrates not on
206 ledge, limitations of previous research, and important issues meriting future investigation.
207 r friends' opinions and our perception about important issues might be distorted.
208 d progress has been substantial, a number of important issues need to be addressed before introductio
209 his gap, this invited commentary relates the important issue of "natural direct effects" to the well-
210 amework in the literature, and highlight the important issue of a theory of subjective utility, which
211               Finally, we review the equally important issue of accuracy.
212                               We address the important issue of formulating the null hypothesis of no
213 arametric MRI and PET imaging to address the important issue of intratumoral heterogeneity in breast
214                                          The important issue of whether CC is automatic has previousl
215 sion of CO2 to liquid fuels, one of the most important issues of contemporary energy and environmenta
216 rmance, new model is needed to address these important issues of MeRIP-seq data.
217                                          Two important issues of microarray bioinformatics are first,
218 nm scale nanopatterns over large areas is an important issue, owing to the performance enhancement su
219 lin sheaths of the auditory nerve (AN) is an important issue particularly because these changes can b
220  prolonged disorders of consciousness raises important issues particularly with respect to their ther
221 er reported in the United States and discuss important issues pertaining to epidemiology, diagnosis,
222                        Here we highlight the important issues raised by the new data and suggest how
223                       This review summarizes important issues raised during a satellite session at th
224                                           An important issue regarding voluntary exercise is whether
225 of the exon 11-associated variants and raise important issues regarding the importance of atypical tr
226 h intensity and brightness of SR beams raise important issues regarding the potential damage inflicte
227 evitability, this article raises a number of important issues regarding these assays that deserve con
228                           Nevertheless, many important issues related to DNA binding, for example, ho
229              In this paper, we address other important issues related to succession of species abunda
230               The present manuscript discuss important issues related to the climate effect and varia
231  article provides information on potentially important issues related to the off-label treatment appr
232                     In this review, we raise important issues related to the PAM's applicability to k
233     This review provides a broad overview of important issues related to WBV therapy for prevention a
234 he academic-industry relationship, including important issues relating to conflict of interest for bo
235 international perspective has been sought on important issues relating to management of the axilla, w
236                                              Important issues remain to be resolved, including the ob
237 ity due to its high charge carrier mobility, important issues remain unresolved that prevent its wide
238                                     However, important issues remain: uncertain patient selection cri
239                                   This is an important issue since we need to achieve a high magnetor
240                                   This is an important issue, since growing evidence links disease pr
241                                   This is an important issue, since it is likely that optimal immunit
242  sequencing have become available to address important issues such as adapter ligation bias, PCR ampl
243 for serum 25(OH)D quantitation and considers important issues such as whether both the D2 and the D3
244 heir model, while compelling, overlooks some important issues, such as mutualistic associations with
245                                     However, important issues, such as the precise mechanisms mediati
246                                              Important issues surrounding biofouling, sensitivity, an
247           The article highlights the current important issues surrounding the anesthetic care of pati
248  recurrent copy number changes in cancer, an important issue that can be addressed using the cross-sa
249 d their potential as therapeutic targets, an important issue that has not been addressed is the impac
250                                           An important issue that has not been investigated is whethe
251  valuable water resource and its reuse is an important issue that must be carried out efficiently.
252 e in the face of progressive cell loss is an important issue that pertains to neurodegenerative disea
253                                  However, an important issue that remains unclear is whether the fund
254 on of a multiple sclerosis (MS) lesion is an important issue that remains unresolved, primarily becau
255  is notable in attempting to address several important issues that challenge the field, including exp
256 fication, optimality and controllability are important issues that emerge in the discussion.
257 alance, and missing data), (2) reporting any important issues that emerge, and (3) exploring variatio
258                       We resolve a number of important issues that have confused the taxonomy of this
259                            There are several important issues that need to be addressed, and foremost
260 epidemiology could prove valuable but raises important issues that need to be considered because diet
261         2020;189(6):491-498) ignores several important issues that need to be considered in the conte
262 ropose that Blackburn (XXXX) ignores several important issues that need to be considered in the conte
263 tion; however, it has also highlighted three important issues that require resolution.
264 tes and the degree of folding cooperativity, important issues that should be considered when designin
265 ents in the Earth's climate system, the most important issue to address is how stable is the desirabl
266 namical aspect of such large responses is an important issue to be clarified for future THz data proc
267 ration of the therapeutic effects is another important issue to be considered, especially because the
268  of composite bread dough could represent an important issue to be explored in dough systems with red
269 al association between statins and HCC is an important issue to examine.
270 velopment of new fungicides against FG is an important issue to reduce cereal infection and economic
271                     Our aim is to bring this important issue to the attention of the plant science co
272                                              Important issues to be addressed include improving vacci
273 xes in vivo, as this remains one of the most important issues to be resolved.
274 rodegenerative disease research, and outline important issues to consider in the transition of stem c
275 plication and functional diversification are important issues to consider in uncovering gene function
276                                              Important issues to consider on preoperative imaging eva
277 statins may be background specific and raise important issues to consider when contemplating clinical
278 , its origins in classic measurement theory, important issues to consider when operationally defining
279 ring for a parent in the adult child's home, important issues to consider, and a framework for clinic
280 ation and the potential for cancer remain as important issues to the future of human space exploratio
281 , naive fitting procedures that ignore these important issues typically provide similarly good fits f
282 ty to the bandwidth measurements and leaving important issues unresolved.
283                     A new study tackles this important issue using bioinformatics approaches to decip
284                     However, addressing this important issue using mouse models that either overly or
285                                  While these important issues warrant attention, patients also need a
286                           In addressing this important issue, we consider a behavior that has been pe
287              To clarify this therapeutically important issue, we have analyzed FLT3(ITD) and NPM1(MUT
288                              To address this important issue, we measured the relaxation of individua
289                              To address this important issue, we recorded neural activity in CA1 as r
290                              To address this important issue, we utilized a genetic model of disrupte
291 ogy-mediated contact with health coaches, an important issue when considering the scalability and cos
292                     Variable selection is an important issue when developing prognostic models.
293                           Data quality is an important issue when managing food composition data sinc
294 activity and suggest that isotype will be an important issue when optimizing reagents for clinical us
295 g IDs from one database to another is a very important issue which is not properly addressed at the m
296                                              Important issues which are highlighted in this work are
297                           Resolution of this important issue will require long-term randomized contro
298                                           An important issue with screening compound libraries is tha
299 signed as a flexible platform that addresses important issues with currently used whole-genome cluste
300 hanisms regulating MCPH1 and also highlights important issues with several commercial MCPH1 antibodie

 
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