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1 of DNA methylation at the germ-line-derived imprinting control region.
2 independent of the CTCF-binding sites in the imprinting control region.
3 nded on functional CTCF binding sites in the imprinting control region.
4 tes at mammalian c-myc promoter and H19/Igf2 imprinting control region.
5 howed nearly complete methylation in the H19 imprinting control region.
6 f2, and Ins2 genes that share a bifunctional imprinting control region.
7 rentially methylated regions (DMRs) known as imprinting control regions.
8 ith the exception of certain loci, including imprinting control regions.
9 hibit distinct methylation patterns at their imprinting control regions.
10 ions that have been confirmed to function as imprinting control regions.
11 ment and DNA methylation of the H19 and Gtl2 imprinting control regions.
12 ly delineate the boundaries of several known imprinting control regions.
13 Lysine 4 and lysine 9 trimethylation marks imprinting control regions.
14 9, KvDMR1, Snrpn promoter/exon 1, and IG-DMR imprinting control regions.
15 decrease in methylation at the H19 and Snrpn imprinting control regions.
16 tely regulated by shared DNA elements called Imprinting Control Regions.
17 ific interactions occur between the IGF2/H19 imprinting control region-1 (ICR1) and ICR2, a region wh
18 gulated by the DNA methylation status of the imprinting control region 2 (ICR2), which is commonly hy
19 a segmental duplication that stabilizes the imprinting control region and a noncanonical enhancer th
20 promoter, which unlike such sites in the H19-imprinting control region and X chromosome, is insensiti
21 tat3(-/-) ESCs show increased methylation at imprinting control regions and altered expression of cog
22 s (PGCs) fail to erase methylation at select imprinting control regions and promoters of meiosis-asso
23 rapidly erases DNA methylation, including at imprinting control regions and promoters of meiotic gene
24 s without altering DNA methylation status of imprinting control regions and regulation of associated
26 LAGL1, INPP5F transcript variant 2, and PEG3 imprinting control regions are not methylated in the mac
27 etic alterations are not confined to 11p15.5 imprinting control regions but also involve other imprin
29 Imprinting at this domain is regulated by an imprinting control region consisting of two distinct ele
30 on upstream of H19 (H19-DMR), serving as the imprinting control region, determines the reciprocal exp
31 er selectivity, whereby CTCF occupancy at an imprinting control region directs downstream enhancers t
32 le, while a weaker interaction involving the imprinting control region element may impede this connec
33 parental chromatin becomes equalized and how imprinting control regions escape from this reprogrammin
34 thylated region 2 (DMR2) of IGF2 and the H19 imprinting control region (H19 ICR) compared with term i
36 erated a mouse model with humanized H19/IGF2 imprinting control region (hIC1) on the paternal allele
37 ryonic days 14.5 (eight dams and 58 fetuses; imprinting control region ICR strain) and 17.5 (21 dams
39 ymai at the syntenic mouse locus is a likely imprinting control region (ICR) for the approximately 12
41 s to the unmethylated maternal allele of the imprinting control region (ICR) in the Igf2/H19 imprinti
42 nal methylation imprint establishment to the imprinting control region (ICR) in the male germline is
43 that localized DNA demethylation at the H19 imprinting control region (ICR) induced by 5-AzaCdR, red
44 The DNA methylation state of the H19/Igf2 imprinting control region (ICR) is differentially set du
45 n the case of the imprinted H19 gene, a 2 kb imprinting control region (ICR) is subject to differenti
46 The most conserved characteristic in the imprinting control region (ICR) is the presence of multi
48 distal chromosome 7 is regulated by a 2.4-kb imprinting control region (ICR) located upstream of the
49 inate from several kilobases upstream of the imprinting control region (ICR) of the domain, from a pr
50 , the zinc-finger protein CTCF, binds to the imprinting control region (ICR) of the genes Igf2 (encod
51 the insulin-like growth factor 2 (Igf2)/H19 imprinting control region (ICR) on chromosome 7 colocali
54 Hyper- and hypomethylation at the IGF2-H19 imprinting control region (ICR) result in reciprocal cha
55 dependent on the presence of an intervening imprinting control region (ICR) situated 2 kb upstream o
56 The imprinting of Igf2 is dependent upon an imprinting control region (ICR) that lies 90 kb 3' of th
57 addition, we found normal methylation of an imprinting control region (ICR) that regulates H19 and I
58 ed by allele-specific DNA methylation at the imprinting control region (ICR), but the underlying mech
59 at the H19 regulator region encompassing the imprinting control region (ICR), concomitant with increa
61 19 gene are regulated by an intervening 2 kb imprinting control region (ICR), which displays parentsp
70 decrease in methylated cytosines that act at imprinting control regions (ICRs) and meiotic genes (sta
71 ion at non-CpG islands within these regions, imprinting control regions (ICRs) and secondary differen
73 Our analysis successfully identifies known imprinting control regions (ICRs) as well as some novel
74 Clusters of imprinted genes are regulated by imprinting control regions (ICRs) characterized by DNA m
76 we trace to the origins of imprinting, binds imprinting control regions (ICRs) in mice and humans.
78 n also changed the methylation levels at the imprinting control regions (ICRs) of these domains in a
79 of several imprinted domains, including the imprinting control regions (ICRs) of Xist, Peg3, H19/Igf
82 Mammalian genomic imprinting is regulated by imprinting control regions (ICRs) that are usually assoc
83 ted the sequences of the mouse and human H19 imprinting control regions (ICRs) to see whether they co
85 d epigenetically at discrete elements termed imprinting control regions (ICRs) with their parental or
88 P57 in the maintenance of DNA methylation at imprinting control regions (ICRs), revealing an allele-s
89 e heart of genomic imprinting in mammals are imprinting control regions (ICRs), which are the discret
96 ining the DNA methylation memory at multiple imprinting control regions in early mouse embryos and em
97 The methylation status of the H19- and Snrpn-imprinting control regions in germ cell clones parallele
98 the SET7/9 histone methyltransferase to the imprinting control regions, inhibiting production of an
99 ories and aberrant acquisition of H3K4me3 at imprinting control regions instead of DNA methylation.
101 1 lowered 24 h nonfasting glucose levels in imprinting control region mice on a high fat diet with d
103 CpG methylation within the promoter and the imprinting control region of MEG3 gene in meningiomas.
104 we dissect the functional components of the imprinting control region of the essential Dlk1-Dio3 loc
106 entae, however, displayed hypomethylation of imprinting control regions of select imprinted genes and
109 dulate the DNA methylation status of the PWS imprinting control region (PWS-ICR) in induced pluripote
110 fecting the neighboring STX16 gene ablate an imprinting control region (STX16-ICR) of GNAS and lead t
111 PWS/AS locus on 15q11-q13 is regulated by an imprinting control region that is maternally methylated
112 lit with the acquisition of a key epigenetic imprinting control region, the differentially methylated
113 promoters of active retrotransposons and to imprinting control regions, the two major regulatory seq
114 genes and the methylation profiles of three imprinting control regions to assess the epigenetic stat
115 w DNA methyltransferases are targeted to the imprinting control regions to initiate and maintain DNA
116 methylated region is an additional principal imprinting control region, which directs Gnas methylatio
117 l-specific methylation at KvDMR1, a putative imprinting control region within intron 10 of the KCNQ1
118 alities, including the methylation status of imprinting control regions within imprinted gene cluster