ライフサイエンスコーパス: impulsive

1 These steep discounters are considered impulsive.

2 neral move faster than subjects who are less impulsive.

3 AR) promote and 5-HT2AR antagonists suppress impulsive action (the inability to withhold premature re

4 el described the data well, with measures of impulsive action and choice separating into two independ

5 Thus, impulsive action and cue reactivity appear to neuromecha

6 These data support the conclusion that impulsive action and impulsive choice are distinct behav

7 To test the hypothesis that impulsive action and impulsive choice represent statisti

8 lunteers to examine the role of serotonin in impulsive action and impulsive choice.

9 At a higher dose (3 mug), M-NX eliminated impulsive action and returned PR breakpoint to low-drive

10 ce serial reaction time task to measure both impulsive action and sustained attention.

11 Using two approaches, we dissociated impulsive action from impulsive choice.

12 hoice serial reaction time task, we measured impulsive action in 1) a panel of 41 BXD recombinant inb

13 cessary and sufficient for the expression of impulsive action in a high-arousal, high-drive appetitiv

14 Intra-PFC M-NX nearly eliminated impulsive action in DRL engendered by hunger, at a dose

15 Genetic mapping of impulsive action in the BXD panel identified a locus on

16 T1BR expression was a predictor of increased impulsive action only.

17 tion time (1-CSRT) task was used to identify impulsive action phenotypes in an outbred rat population

18 aneously occurring individual differences in impulsive action reflect variation in the cortical 5-HT2

19 ctive 5-HT2AR antagonist M100907 to suppress impulsive action relative to LI rats.

20 een Nrg3 expression in the mPFC and level of impulsive action shown here provides a mechanism by whic

21 mpulsive behavior are behavioral inhibition (impulsive action) and delayed gratification (impulsive c

22 ly increased 4-CSRTT premature responses (or impulsive action), which is remarkably similar to the pr

23 st, the absence of 5-HT1BRs caused increased impulsive action, but not impulsive choice.

24 enes regulating impulsivity, specifically of impulsive action, in mice.

25 Virally increasing Crem levels decreased impulsive action, thus establishing a causal relationshi

26 salience coding, and impulsive choice versus impulsive action.

27 thought to play a role in the regulation of impulsive action.

28 )), may drive the predisposition to inherent impulsive action.

29 ity locus (Impu1) confirmed its influence on impulsive action.

30 c loss of the mPFC 5-HT2CR induced aggregate impulsive action/cue reactivity, suggesting that depress

31 vide strong evidence that NAc FSIs constrain impulsive actions, most likely through gamma-aminobutyri

32 y facilitate inhibition to mitigate risks of impulsive actions.

33 indicating heightened stress, in response to impulsive additional noise (playbacks of recordings of p

34 characterising those persons who become more impulsive after subthalamic DBS, an intervention in whic

35 Impulsive aggression and borderline personality disorder

36 ior, studies of white matter connectivity in impulsive aggression are warranted.

37 spring mood disorder at each time point, and impulsive aggression as a precursor of mood disorder.

38 orts the hypothesis that lithium use reduces impulsive aggression in addition to stabilizing mood.

39 Interventions that target mood disorder and impulsive aggression in high-risk offspring may attenuat

40 familial transmission (eg, mood disorder and impulsive aggression).

41 rs, such as depression, childhood abuse, and impulsive aggression, report inconsistent results.

42 antisuicidal properties through reduction in impulsive aggression.

43 s the categorical expression of pathological impulsive aggression.

44 ts with histories of recurrent, problematic, impulsive aggressive behavior and in nonaggressive compa

45 trol study in a clinical research program in impulsive aggressive behavior at an academic medical cen

46 in individuals with recurrent, problematic, impulsive aggressive behavior.

47 expression and exacerbates the expression of impulsive-aggressive behavioural traits in CD1 aggressiv

48 RNA that acts on MAOA expression to regulate impulsive-aggressive behaviours.

49 Elevated MAALIN in the dentate gyrus of impulsive-aggressive suicides was associated with lower

50 Impulsive and aggressive behaviors are both modulated by

51 t with management of developmentally limited impulsive and aggressive behaviors rather than psychotic

52 High impulsive and aggressive traits associate with poor beha

53 ular mechanisms underlying the expression of impulsive and aggressive traits remain poorly understood

54 creased serotonin metabolites with increased impulsive and aggressive traits.

55 rical disorder of ADHD influence hyperactive-impulsive and attentional traits in the general populati

56 al systems and their role in contributing to impulsive and compulsive features of drug dependence.

57 By contrast, increased levels of impulsive and compulsive personality traits and limbic-s

58 type, derived from bi-factor modelling of 33 impulsive and compulsive problem behaviours.

59 Impulsive and compulsive symptoms are common, tend to co

60 e that prenatal nicotine exposure makes rats impulsive and disrupts firing of mPFC neurons that carry

61 eterminants that may perpetuate the cycle of impulsive and harm-avoidance behaviours.

62 nt of frontotemporal dementia, presenting as impulsive and impetuous behaviours that are often diffic

63 l illness whose manifestations often include impulsive and risk-taking behavior.

64 Our findings suggest that clinically impulsive and risky decision-making are related to subje

65 mechanisms underlying a range of affective, impulsive, and aggressive neuropsychiatric disorders.

66 by making individuals less cautious and more impulsive, and by amplifying the value of punishment.

67 Using an ADHD rat model, we demonstrate that impulsive animals are neurochemically and behaviorally m

68 nted the development of compulsivity in high-impulsive animals.

69 network perturbation engenders disorganized, impulsive appetitive responses.

70 ns drives proximate reward bias by promoting impulsive approach to nearby reward-associated objects.

71 ive/inattentive (ASRS part A), hyperactivity/impulsive (ASRS part B), and combined (total) ASRS score

72 impulsive traits (BIS-11 questionnaire) and impulsive behavior (by means of the Delay Discounting Qu

73 sorder, bipolar disorder, schizophrenia, and impulsive behavior all share in common defects in these

74 Effects of lead exposure on impulsive behavior and cognition were modified by mercur

75 Two behavioral features often considered in impulsive behavior are behavioral inhibition (impulsive

76 Here, we studied the regulation of impulsive behavior by fast-spiking interneurons (FSIs),

77 Dysregulation of impulsive behavior by increased DYN/KOR activity could s

78 associated with DNMT1 upregulation, whereas impulsive behavior could be dissociated from inattention

79 ess practice may be effective for redressing impulsive behavior derived from inhibitory motor control

80 a distinct set of 5-HT1B receptors modulates impulsive behavior during adulthood.

81 inhibition deficiency related to hyperactive-impulsive behavior in ADHD, further emphasizing the poss

82 Lesions of AI reduced impulsive behavior in HI rats, which were also highly su

83 Prior literature links impulsive behavior in rodents to gamma-aminobutyric acid

84 however the relationship between orexin and impulsive behavior is incompletely characterized.

85 Here, we investigated whether impulsive behavior observed following cocaine exposure r

86 Rats were screened for impulsive behavior on a five-choice serial reaction time

87 Rats were screened for impulsive behavior on the five-choice serial reaction ti

88 lity traits [the short version of the UPPS-P Impulsive Behavior Scale, and the Barratt Impulsiveness

89 For example, hyperactive-impulsive behavior scores at age 8 years were 0.9 points

90 Impulsive behavior such as steep temporal discounting is

91 Hyperlocomotion and impulsive behavior were reversed by methylphenidate, a p

92 chopathology (including depression, anxiety, impulsive behavior) in the children was negatively corre

93 , and caffeine misuse, perceived stress, and impulsive behavior).

94 is implicated in mood regulation, control of impulsive behavior, and in processing aversive and rewar

95 ortex (PFC) plays a critical role in curbing impulsive behavior, but the underlying circuit mechanism

96 Alcohol use may also increase impulsive behavior, including impaired response inhibiti

97 itive control may be required to prevent any impulsive behavior, including stopping physical effort w

98 selective roles in regulating compulsive and impulsive behavior, respectively.

99 serotonin (5-HT) receptors are implicated in impulsive behavior, separate groups of rats received mic

100 information processing mechanism underlying impulsive behavior, we investigated stimulus and action

101 have been associated with greater levels of impulsive behavior, which contribute to the higher debt

102 educing serotonin neurotransmission promotes impulsive behavior.

103 the pathogenesis of anxiety or reckless and impulsive behavior.

104 dysfunction of cognitive domains regulating impulsive behavior.

105 ate a complex pattern of association between impulsive behaviors and BMI in healthy young American-Eu

106 tion may be of use in correcting maladaptive impulsive behaviors and provide further evidence for dis

107 to a psychometric measure of impulsivity or impulsive behaviors in general.

108 y economic models hold that instrumental and impulsive behaviors underlie human social decision makin

109 Rodent research has focused largely on impulsive behaviors, often gauged by premature respondin

110 rather than punishment avoidance in driving impulsive behaviors.

111 the central-medial amygdala, which subserves impulsive behaviors.

112 stress levels, anger proneness, and hostile, impulsive behaviors.

113 s in genetic and molecular investigations of impulsive behaviors.

114 atric battery and a virtual casino to assess impulsive behaviour in a naturalistic fashion, 55 patien

115 ansmitters glutamate and GABA correlate with impulsive behaviour in several neuropsychiatric diseases

116 ovide further evidence of STN involvement in impulsive behaviour in the PD population.

117 ay promote innovation as well as problematic impulsive behaviour, including drug abuse.

118 ioural read-out of explorative, risk-taking, impulsive behaviour.

119 ing for the future may encourage apparently "impulsive" behaviour when the future is anticipated to b

120 an individual gets from missed ART doses and impulsive behaviours that lead to relapse and poor, even

121 associated with a presumably more efficient impulsive brain system, manifested through reduced grey

122 (3) starlings' choices are not irrationally impulsive but are instead directly interpretable in term

123 ial cognition, social function, and level of impulsive choice also remained undisturbed.

124 ort the conclusion that impulsive action and impulsive choice are distinct behavioral phenotypes with

125 There was no effect of TD on impulsive choice as indexed by the reward delay-discount

126 oint and play a critical role in suppressing impulsive choice by regulating decision trade-off.

127 dol reduced the nondecision time and reduced impulsive choice compared with placebo.

128 These differences in impulsive choice could be linked to gender differences a

129 or bipolar disorder or suicide to modify the impulsive choice dimension of this diseases.

130 ctivation just prior to decisions attenuated impulsive choice in both young and aged rats.

131 in females, whereas orchiectomies increased impulsive choice in males.

132 ivation of 5-HT1A receptors in OFC increases impulsive choice in the adjusting delay procedure.

133 ipt of the small, immediate reward increased impulsive choice in young rats but had no effect in aged

134 est the hypothesis that impulsive action and impulsive choice represent statistically independent beh

135 These data show that male rats exhibit less impulsive choice than females and that this difference i

136 underpins value versus salience coding, and impulsive choice versus impulsive action.

137 Impulsive choice was not altered significantly by MPH, A

138 impulsive action) and delayed gratification (impulsive choice).

139 mediate over large, delayed rewards (greater impulsive choice).

140 ceipt, is an established behavioral model of impulsive choice, a key component of a broader impulsivi

141 vity variables using three broad categories: impulsive choice, action and personality.

142 our hypothesis, L-DOPA had no main effect on impulsive choice, but reduced risk-seeking for gains in

143 To clarify the impact of dopamine on impulsive choice, we administered 150 mg L-DOPA to 87 he

144 and eticlopride infused into mPFC increased impulsive choice, whereas 8-OH-DPAT infused into OFC dec

145 s caused increased impulsive action, but not impulsive choice.

146 were sufficient to bidirectionally influence impulsive choice.

147 oaches, we dissociated impulsive action from impulsive choice.

148 he role of serotonin in impulsive action and impulsive choice.

149 whereas 8-OH-DPAT infused into OFC decreased impulsive choice.

150 e the systemic effect of ADHD medications on impulsive choice.

151 ng state VLF oscillations during waiting and impulsive choice.

152 gic signaling would benefit and exhibit less impulsive choice.

153 dopamine signaling are associated with high-impulsive choice.

154 dopamine signaling are associated with high-impulsive choice.

155 sorder, a comprehensive meta-analysis of all impulsive cognitive domains has yet to be conducted.

156 Thirty-one patients with impulsive compulsive behaviours and Parkinson's disease

157 The majority of patients with impulsive compulsive behaviours had dopamine dysregulati

158 Patients with Parkinson's disease and impulsive compulsive behaviours had lower alpha-synuclei

159 Impulsive compulsive behaviours in Parkinson's disease h

160 ared to 29 Parkinson's disease cases without impulsive compulsive behaviours matched by age, sex, dis

161 of individuals with Parkinson's disease and impulsive compulsive behaviours was confirmed on western

162 ulation of the ventral striatum resulting in impulsive compulsive behaviours.

163 y contributes to individual vulnerability to impulsive-compulsive behavior in rats.

164 linical and structural imaging predictors of impulsive-compulsive behaviour (ICB) in de novo Parkinso

165 ncorrelated phenotypic dimensions: a general impulsive-compulsive dimension; and two narrower phenoty

166 Depression Inventory, and Questionnaire for Impulsive-Compulsive Disorders in Parkinson Disease Rati

167 baseline according to the Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease (Q

168 SPECT) and ICD assessment (Questionnaire for Impulsive-Compulsive Disorders in Parkinson's Disease sh

169 d as positive score on the Questionnaire for Impulsive-Compulsive Disorders in PD.

170 in daytime sleepiness, anxiety, depression, impulsive-compulsive disorders, blood pressure, urate, a

171 e disorder, in a potentially new spectrum of impulsive-compulsive disorders.

172 .36) for the general dimension, This general impulsive-compulsive phenotype may reflect a quantitativ

173 e to pathological computational processes in impulsive/compulsive psychiatric disorders.

174 that relapse to smoking is due to a lack of impulsive control, which is thought to be due to altered

175 -to-ground lightning flashes, manifesting an impulsive coupling mechanism between lower and upper atm

176 investigate the effect of STN stimulation on impulsive decision making, we used the Iowa Gambling tas

177 e extent to which these tendencies relate to impulsive decision-making and behaviors in real-life set

178 anding of the neurobiochemical mechanisms of impulsive decision-making and related mental disorders.

179 unt of disorders characterized by clinically impulsive decision-making, and provide targets for evalu

180 Impulsive decisions arise from preferring smaller but so

181 l and frequency-specific dynamics supporting impulsive decisions on a fine-grained temporal scale usi

182 ng framework to tackle this difficulty using impulsive differential equations.

183 ICD subtypes assessed by modified Minnesota Impulsive Disorder Interview (mMIDI).

184 Furthermore, the pro-impulsive effects of KOR activation were rescued by pret

185 s through the application of intense fields, impulsive electromagnetic stimulation, and nanostructuri

186 Impulsive errors thus entail both a motor system capture

187 zation task that enticed the animals to make impulsive errors.

188 including by corotating interaction regions, impulsive events driven by acceleration near the Sun, an

189 vistic energies via at least two processes: 'impulsive' events, which are usually associated with mag

190 es generated under resonant and off-resonant impulsive excitation conclusively reveals coherent wavep

191 lations of the cantilever deflection when an impulsive excitation is given (as in the band excitation

192 ly understood, and could be dominated by the impulsive flash of thermonuclear energy, prolonged optic

193 hat motivate PD+HS, these patients were less impulsive for the immediate reward.

194 The myosin cross-bridge applies impulsive force to actin while consuming ATP chemical en

195 These pulses produce high fidelity impulsive forces that separate the atom into widely sepa

196 ed in terms of a harmonic oscillator with an impulsive forcing, and this hypothesis is consistent wit

197 sk reliably and reproducibly identified high impulsive (HI) and low impulsive (LI) action phenotypes;

198 Stable high-impulsive (HI) and low-impulsive (LI) phenotypes were id

199 egion of the insular cortex, in which highly impulsive (HI) rats expressed lower zif268 mRNA levels.

200 /6J (B6) mice (alcohol preferring) were more impulsive in the 5CSRTT than DBA2/J (D2) mice (alcohol a

201 es underlying the increased vulnerability of impulsive individuals to develop cocaine addiction remai

202 uent first-stage choices, particularly among impulsive individuals under stress.

203 20*) was reported to segregate with severely impulsive individuals, whereas 5-HT2B mutant (Htr2B(-/-)

204 d, and this tendency was exacerbated in more impulsive individuals.

205 s context, photo-excitation is treated as an impulsive injection of electronic energy that is transfe

206 f primary (selfish, uncaring) and secondary (impulsive, irresponsible) psychopathic personality trait

207 e sustained untethered flight (as opposed to impulsive jumping(8) or liftoff(9)).

208 rmal electrons, which are generated in small impulsive ( less, similar30 seconds) heating events call

209 cibly identified high impulsive (HI) and low impulsive (LI) action phenotypes; HI action predicted hi

210 , neuronal, and glial protein markers in low-impulsive (LI) and high-impulsive rats.

211 Stable high-impulsive (HI) and low-impulsive (LI) phenotypes were identified from an outbre

212 in rodents, we identified high (HI) and low impulsive (LI) rats in the 1-choice serial reaction time

213 he CLA-PFC pathway increased and reduced the impulsive-like behavior (i.e., premature responses), res

214 in receptor (OXR) antagonists on measures of impulsive-like behavior in rats were evaluated using the

215 Furthermore, hyperactive-impulsive-like behavior was induced by reducing the expr

216 , working memory and attention deficits, and impulsive-like behavior.

217 ese changes coincided with perseverative and impulsive-like responding for sucrose pellets and sustai

218 2R signaling coincide with perseverative and impulsive-like responding for sucrose, a disaccharide co

219 low accuracy, slow speed), and Subtype 3 was impulsive (low accuracy, fast speed).

220 Our measurements suggest that there is an impulsive mechanism associated with solar-wind energizat

221 d and applied them to develop a bio-inspired impulsive mechanism that maximizes momentum transfer to

222 ory and movement processing and suggest that impulsive movements arise when sensory processes become

223 We suggest that during impulsive movements, flexible organisms like fishes can

224 rankings and that humans appear irrationally impulsive (namely, show maladaptive preference for immed

225 ort a translational neuroscience approach to impulsive neurological disorders and indicate the potent

226 xplain why fish that experienced 12 weeks of impulsive noise showed no differences in stress, growth

227 Collies were more impulsive on average, consistent with the original purpo

228 activation reduces food intake and inhibits impulsive operant responding for palatable food via down

229 Suicidal behavior (SB) can be impulsive or methodical; violent or not; follow a stress

230 cle at some distance from a plate undergoing impulsive or oscillatory motion.

231 matic' response system, which some consider 'impulsive' or 'irrational', or our supposedly more ratio

232 ve association with ADHD traits (hyperactive-impulsive, p = .0039; inattentive, p = .037).

233 We found that more impulsive participants were more likely to repeat second

234 tern of vmPFC-frontoparietal connectivity in impulsive people with suicidal behavior, which may under

235 ehavior, but only among men with dominant or impulsive personality styles.

236 psychiatric disorders.SIGNIFICANCE STATEMENT Impulsive personality traits (IPTs) are heritable traits

237 nome-wide association studies on measures of impulsive personality traits [the short version of the U

238 Impulsive personality traits and drug experimentation sh

239 the relationship between different types of impulsive personality traits and various psychiatric dis

240 Impulsive personality traits are complex heritable trait

241 efore, KOR activation was shown to induce an impulsive phenotype that was nor-BNI-sensitive.

242 onstrated a dissociable effect of U50,488 on impulsive phenotypes related to intolerance to delay or

243 ized that KOR activation could contribute to impulsive phenotypes.

244 the compulsiveness for food in Low- and High-impulsive rats by measuring the food eaten in the aversi

245 te that the reduction in impulsivity in high-impulsive rats by prior cocaine exposure may be mediated

246 eft, but not right, ventral striatum of high-impulsive rats compared with low-impulsive rats.

247 t on rats' inherent impulsivity because high impulsive rats demonstrated a greater percentage of smal

248 depended on rats' inherent impulsivity, with impulsive rats exhibiting a stronger neural shift toward

249 High- and low-impulsive rats identified in the five-choice serial reac

250 In transition-stage tests, low-impulsive rats showed a significant dose-dependent reduc

251 ovel markers underlying the vulnerability of impulsive rats to cocaine addiction that localize to the

252 Then, we allowed Low- and High-impulsive rats to self-administer a highly palatable die

253 t reduction in cocaine seeking, whereas high-impulsive rats were still unaffected by alpha-flupenthix

254 ray matter density in the left NAcbC of high-impulsive rats, with corresponding reductions in this re

255 otein markers in low-impulsive (LI) and high-impulsive rats.

256 esponding (DRL) task to select Low- and High-impulsive rats.

257 tum of high-impulsive rats compared with low-impulsive rats.

258 d by external US sources in the harmonic and impulsive regimes of wave propagation.

259 By combining near-impulsive resonant and non-resonant excitation, the desi

260 t the LHb participates in the suppression of impulsive responding for cocaine through the activation

261 e) of MCH communication to the vHP increases impulsive responding in rats, indicating that perturbing

262 establishment of attosecond chronoscopy, the impulsive response of positive-energy electrons to elect

263 sive brain stimulation improved control over impulsive response tendencies, but only when participant

264 l phenotype correlated with novelty-seeking, impulsive response to reward, and vulnerability to addic

265 ting conflict anticipation to the control of impulsive response, which is consistent with earlier stu

266 basal ganglia, play a key role in inhibiting impulsive responses in a go/no-go task.

267 individual variation in proactive control of impulsive responses remain unknown.

268 This review examines impulsive responses to positive and negative emotions, w

269 a choice reaction-time task known to trigger impulsive responses, leading to fast errors that can be

270 ction, but more in unconscious inhibition of impulsive responses.

271 tection, but less in conscious inhibition of impulsive responses.

272 cognitive control is the ability to rein in impulsive responses.

273 efrontal areas, resulting in the increase of impulsive reward-seeking behaviors that are often observ

274 Impulsive risk taking contributes to deleterious outcome

275 cal questions related to the impact of these impulsive runoffs is "are flash floods more efficient in

276 vents and may be a trait increasing risk for impulsive SB, at least over 2 years.

277 The location of impulsive seismic events indicative of lava reaching the

278 Our theory predicts that people who are more impulsive should in general move faster than subjects wh

279 dit can be adapted to almost any stereotyped impulsive signal.

280 social-economic decisions and result in more impulsive social-economic choice behavior.

281 intensively studied, damping effects during impulsive spin excitations are assumed to be negligible

282 complementary Brillouin Light Scattering and Impulsive Stimulated Light Scattering coupled with a dia

283 f nanoscale graphite following an ultrafast, impulsive strain excitation.

284 ent quantities while also inferring the bulk impulsive strain profile by using high spatial-resolutio

285 ow that the food addiction phenotype in high impulsive subjects is characterized by an increased expr

286 , but reduced risk-seeking for gains in more-impulsive subjects.

287 bility to slow down responses and can induce impulsive suboptimal decisions.

288 represents a valid model for the Hyperactive-Impulsive subtype of ADHD and therefore may be used in f

289 ediated the relationship between hyperactive impulsive symptoms and both poor focused attention and i

290 ge is related to inattentive and hyperactive/impulsive symptoms in children and adolescents with Down

291 from polygenic risk for ADHD to hyperactive-impulsive symptoms through white matter microstructure,

292 ons of childhood inattentive and hyperactive-impulsive symptoms were conducted to predict smoking out

293 response impulsivity, choice impulsivity and impulsive tendency) varied between GD patients and healt

294 e found that pathological gamblers were more impulsive than controls in a stop-signal task and attrib

295 Sx-5CSRT, in addition to being screened for impulsive traits (BIS-11 questionnaire) and impulsive be

296 ed whether affective lability, aggressive or impulsive traits explain childhood trauma's effects on S

297 auma, affective lability, and aggressive and impulsive traits predicted greater SI variability.

298 The impulsive two-state (I2S) model was used to describe the

299 optimal dopamine signaling would become more impulsive when receiving dopamine-enhancing drugs, where

300 hen subjected them to a series of controlled impulsive wind gusts delivered by an air piston and expe