ライフサイエンスコーパス: in itself

1 yproduct of reasoning, rather than as an end in itself.

2 usically induced sadness cannot be enjoyable in itself.

3 ntration of microorganisms, akin to an organ in itself.

4 eventive health measures and as a policy end in itself.

5 re acting according to a norm becomes a goal in itself.

6 useholds and should not be considered a goal in itself.

7 ated from the technology than on the process in itself.

8 rnate livelihood options, rather than an end in itself.

9 t that choosing the default may be rewarding in itself.

10 n of the individual enantiomers was biphasic in itself.

11 morphism is indeed the associated as well as in itself a causal variant.

12 rom the cranial nerves and may be considered in itself a component of visceral sensation.

13 x remodeling associated with pathogenesis is in itself a positive regulator of the cell cycle through

14 vasion, a finding exclusive to pathology and in itself a predictor of HCC recurrence after OLT.

15 specific genetic perturbations, establishing in itself a resource of validated guide RNA sequences.

16 on increases risk for hypertension, which is in itself a strong risk factor for cardiovascular diseas

17 de evidence that inclusion-body formation is in itself a sufficient cause of neurodegeneration, and t

18 Interestingly, although in itself a weak stimulator of cytokines, M. leprae prim

19 fatal food-allergic reaction; asthma is not, in itself, a strong predictor for fatal anaphylaxis.

20 rigorously curated subcellular proteomes is in itself also important as a parts list for plant and s

21 to mouse and rat embryo fibroblasts did not, in itself, alter their growth.

22 may be more related to COVID-19 than to ECMO in itself, although this needs confirmation.

23 k is the transcription-translation machinery-in itself an autocatalytic network comprising several co

24 Here the retrograde membrane is, in itself, an anterograde carrier.

25 and, because of the minor effect of surgery in itself, an effect of IOL type seems highly unlikely.

26 receptor shows improved photostability, both in itself and in complex with squaraines.

27 of eliciting polysynaptic GABA(A) IPSCs both in itself and in nearby cholinergic interneurons.

28 s of organohalides has become a mature field in itself, and applying these technologies has allowed f

29 hing the structure is not a research problem in itself, and bond ruptures and dissociations can be fo

30 , is an underestimated global health problem in itself, and due to a causative relationship with othe

31 erform these reforms is a scientific problem in itself, and economics has several scientific methods

32 This structure, in itself, appears consistent with a mechanism involving

33 rly for reduced left pulmonary artery growth in itself as no factors investigated in this study were

34 formic acid production, which is a commodity in itself as well as a feedstock for the synthesis of ot

35 he donor pool, it is unlikely that this will in itself be able to bridge the gap.

36 and suggest that Tyr phosphorylation may not in itself be sufficient to cause the departure of PY-STA

37 The sub-population of cancer stem cells in itself becomes highly heterogeneous dictating populat

38 o-dimensional system is not only interesting in itself but also allows access to the subtle and rich

39 bout in evolution not because it is adaptive in itself but as a necessary consequence of man's eminen

40 ry strategies that do not solely rely on EPR in itself but can offer interesting pharmacological, phy

41 cluster spacing which is a strong classifier in itself but improved with the addition of the monoisot

42 derpinnings of psychiatric illness is useful in itself, but also affords the opportunity to identify

43 Hydrophobicity has little effect in itself, but aromatic residues lead to strong compacti

44 AFLD is not only an important global problem in itself, but it is likely to be associated with increa

45 wn to elicit late PC), demonstrating that NO in itself can activate NF-kappaB in the heart.

46 pressure or by the underlying disorder (that in itself can be acquired or genetic).

47 is not unusual in personality disorders and in itself can be associated with medical illnesses.

48 c control may result in hypoglycaemia, which in itself can be detrimental.

49 it, yet a series of stages each advantageous in itself can be shown to exist allowing evolution to ge

50 We find that pattern coherency in itself can drive perceptual alternations, and the pat

51 stress is a strong demonstration that stress in itself can have a purely cognitive origin.

52 enced by the geometry of the surface, which, in itself, can be a dynamical entity.

53 ces a re-examination of whether gene number, in itself, can be taken as any real guide to complexity.

54 of a SNO-Hb/Band 3 protein assembly does not in itself cause NO release, even in the presence of glut

55 ously, denervation of adult muscles did not, in itself, cause TSC mitosis.

56 ion signal, which does not cause termination in itself, causes catalytic inactivation and backtrackin

57 peated association, the involuntary movement in itself comes to produce some key temporal features of

58 makes clear that allelic inclusion does not in itself compromise central tolerance.

59 at the meta position that, however, does not in itself contribute to a new conduction pathway.

60 We propose that this vacuolation, in itself, contributes to the virulence of V. cholerae s

61 ns and guidelines stating that fever is not, in itself dangerous, however these fears persist.

62 In itself, dehydroascorbate did not affect cytosolic or

63 ice revealed that prolonged NO production is in itself deleterious and that a major function of the T

64 roximal cell-state, a transformation that is in itself dependent on BMP signal transduction.

65 mean blood pressure (12 +/- 3 mm Hg), which in itself did not alter cell firing.

66 The endoscopy procedure in itself did not lead to any complications.

67 e bare material and the cell membrane, which in itself disregarding specific interactions, causes a d

68 scapes analyzed, but antisense transcription in itself does not affect sense transcription at the sam

69 ggest that disruption of the circadian clock in itself does not compromise mammalian DNA repair and D

70 s not been fully made and that such ideation in itself does not explain a willingness to engage in pu

71 f plasticity (intrinsic plasticity; IP) that in itself does not involve alterations in synaptic stren

72 asia causes narrowing of the canal, but that in itself does not result in visual loss.

73 ombination and, therefore, allelic inclusion in itself does not serve as a B cell tolerance mechanism

74 Accordingly, c-kit positivity, in itself, does not define the embryonic origins, lineag

75 While this is in itself encouraging, interpretation of the data presen

76 rmore, our data demonstrate that Rab3 is not in itself essential for synaptic membrane traffic but fu

77 ve stability," but this observation does not in itself explain how a loopless structure might arise.

78 incidence without gender bias, but does not in itself generate the full spectrum of lupus-like disea

79 Administration of dexamethasone in itself had no effect on the intrinsic excitability of

80 eminated tumors, protein kinase B disruption in itself had no effect on tumor survival but was synerg

81 This in itself has stimulated the interest of several pharmac

82 55 nm band (S(sigma)(Cys) -> T1Cu(2+)) which in itself indicates the electronic route of proton-coupl

83 g element alleviates WNT repression, but is, in itself, insufficient to promote regeneration.

84 trengthened by quantification, although this in itself introduces another level of complexity and pot

85 This tumor cell-stromal cell interaction in itself is a form of commensalism, because it has been

86 is a mediator of antitumor drug activity and in itself is a promising agent for the treatment of huma

87 he causative agent of the common cold, which in itself is a relatively trivial infection; however, in

88 However, the generation of ANA in itself is insufficient to account for the severity of

89 n of the TATA element, suggesting that EBNA2 in itself is insufficient to mediate stable targeting of

90 , Fisher emphasized that evolutionary change in itself is likely to be an important component of "env

91 ates leads us to conclude that such capacity in itself is not a limiting factor for speech comprehens

92 f transposons and it suggests that structure in itself is not a reliable character for transposon cla

93 Third, lack of auto-inhibition in itself is not necessarily detrimental to KHC function

94 nclude that the level of expression of CD154 in itself is not responsible for affecting the immune re

95 s to the phosphorylation of Rb but that this in itself is not sufficient for allowing differentiated

96 ions of our study is that calmodulin binding in itself is not sufficient for CaMKII activation, altho

97 downstream from mRNA polysome release, which in itself is not sufficient for mRNA PB localization.

98 ts upward and poleward, but species movement in itself is not sufficient to establish climate causati

99 This in itself is not sufficient to induce arachidonic acid r

100 ed to islet autoantigens, but autoreactivity in itself is not sufficient to induce diabetes.

101 EEG-R testing in itself is not sufficiently reliable for outcome predi

102 psB prevents closure of the septal ring that in itself is PBP2x-dependent.

103 y NO donors provides direct evidence that NO in itself is sufficient to elicit this cardioprotective

104 We report here that the 134 kb deletion, in itself, is insufficient to cause sex reversal.

105 etrotransposition, but that differentiation, in itself, is not sufficient to reactivate previously si

106 the first report that upregulation of iNOS, in itself, is sufficient to reduce infarct size.

107 is found to lack any photocatalytic activity in itself-is hypothesized to react with surface defects

108 he evolving pattern of neural activation may in itself lead to abnormal behavior.

109 single regulatory domain interface does not, in itself, lead to the positive cooperativity of inhibit

110 The idea that one's pain is uncontrollable in itself leads to stress.

111 This treatment does not in itself make a fly susceptible to Escherichia coli inf

112 introduction of assortative mating does not, in itself, markedly affect the estimate of the recombina

113 dence that carriage of the ATC/TTC haplotype in itself may increase the influx of neutrophils in infl

114 a costimulatory pathway, although desirable in itself, may prevent the ligation of an essential regu

115 tly showed that membrane shape/curvature can in itself mediate the recruitment of lipidated proteins.

116 Our findings demonstrate that allopolyploidy in itself need not be associated with increased salinity

117 he DNA-binding properties of the proteins is in itself not sufficient to understand their architectur

118 f the vascular supply as the essential means in itself of not only causing the morphologic lesions in

119 However, if the mutator mutation is not in itself oncogenic, acquiring that mutation would add a

120 Occupation of this site in itself, or events downstream, would convert a vesicle

121 ms, which underlines that CC distress is not in itself pathological.

122 elimination of fibrin from the lung was not in itself protective, the beneficial effect of PAI-1 def

123 ., acting according to a norm becomes an end in itself rather than merely a tool in achieving certain

124 crossover between wheat chromosomes does not in itself reduce wheat fertility when promotion of homol

125 selectively essential function without being in itself required for core activities of neurons, such

126 ungal association with a phototroph does not in itself result in fungal CAZyme loss, and lends suppor

127 Artificial activation of NPF neurons was in itself rewarding and precluded the ability of ethanol

128 This finding did not, in itself, rule out the possibility that mioC transcript

129 , while complementary to other tests, is not in itself sufficient for the diagnosis of PV.

130 usly expressed Rel/NF-kappaB proteins is not in itself sufficient for transformation.

131 l fate hierarchy, establish that Ngn3 is not in itself sufficient to commit cells to the endocrine fa

132 We show that while loop formation is not in itself sufficient to explain action at a distance, in

133 ity of the oocyte microtubule network is not in itself sufficient to generate anterior asymmetry, and

134 resident antigen-specific CD4(+) T cells is in itself sufficient to induce such a phenotype.

135 roliferative response, overexpression is not in itself sufficient to induce turmorigenesis.

136 ion of the (1-32)SCP(2) portion of SCP(2) is in itself sufficient to mediate intermembrane sterol tra

137 sted that glass formation (vitrification) is in itself sufficient to stabilize dry biomaterials.

138 vitrification is indeed required, it is not in itself sufficient.

139 he requirement of high interconnectivity is, in itself, sufficient to account for the existence of th

140 s, and siRNA reduction of Sulfs in OECs was, in itself, sufficient to induce boundary formation.

141 thermore, the chemical composition of a food in itself tells us very little about whether or not that

142 h accompanies attenuation, is not sufficient in itself to attenuate pathogenic MDVs.

143 coupled to ATP hydrolysis is not sufficient in itself to explain how ATP hydrolysis facilitates DNA

144 ane phospholipid, and its loss is sufficient in itself to induce cell death.

145 Although not in itself toxic, UCN-01 increased the cytotoxicity of TM

146 alpha-latrotoxin to these receptors does not in itself trigger exocytosis but serves to recruit the t

147 ng, in the same multivariate analysis, ISBCS in itself was associated with a significantly lower risk

148 ot correlate with microvessel density, which in itself was not a significant predictor of progression

149 However, no single parameter model in itself was predictive.

150 We also found that transplantation, in itself, was associated with bcl-2 expression in the h

151 partment became a place, and little universe in itself, where young scientists from all over the worl