ライフサイエンスコーパス: in lieu of

1 clinically meaningful complication clusters in lieu of 18 postoperative morbidities, which will faci

2 to contain either GTT or TGACTGTT sequence, in lieu of 20,214 or 18,895 bp, respectively, of the bac

3 Abasic lesions in the nonscissile strand in lieu of +4G, +3G, +2A, and +1A reduced the rate of cl

4 itution at the 665 junction site on the cage in lieu of a 666 substitution.

5 ating ribonucleotides by virtue of a leucine in lieu of a canonical aromatic steric gate.

6 In lieu of a cladogram of formicine genera, generalized

7 ession sequence tags (ESTs) as the reference in lieu of a complete genome sequence.

8 In lieu of a consistent source of experimentally measure

9 nest cameras installed on a subset of nests in lieu of a controlled feeding study (TDF(CAM) ).

10 Thus, in lieu of a crystal structure for the AAV type 2 amino-

11 In lieu of a crystallographic structure of the complete

12 formation of the cohesin-dockerin interface, in lieu of a definitive crystal structure.

13 The application of a new perovskite in lieu of a degraded one exhibited a full regeneration

14 Even in lieu of a dependable species concept for asexual orga

15 the formation of a free carbene intermediate in lieu of a direct, one-step isomerization process was

16 lution was supplemented with isotonic saline in lieu of a drug.

17 vin-like mechanism, where the substrate acts in lieu of a flavin cofactor.

18 In lieu of a functional genetic system to investigate fl

19 corresponding enhancement of dopamine efflux in lieu of a lengthy withdrawal period is uncommon, but

20 ers and co-designed computational processing in lieu of a lens, we demonstrate the use of silicon pho

21 tor CsSnI(3) can be used for hole conduction in lieu of a liquid electrolyte.

22 en females were allowed to consume a cricket in lieu of a male, suggesting that it is the consumption

23 o the furrow and mark the center of the cell in lieu of a midbody/phragmoplast.

24 ts formation of two separate sodalite phases in lieu of a mixed-anion sodalite.

25 bedded in the whole urban traffic condition, in lieu of a myopic description based on the average spe

26 re an organic TADF photocatalyst can be used in lieu of a noble metal complex photocatalyst.

27 The non-breast cancer group was used in lieu of a population-based, healthy control group, wh

28 rthermore, a constant assisting load, likely in lieu of a power stroke, was shown to rescue forward m

29 In lieu of a prospective, randomized multicenter trial,

30 Intermediate 3 is photolabile, so, in lieu of a Raman spectrum, IR was used to obtain vibra

31 By introducing single 2'-5' phosphodiesters in lieu of a standard 3'-5' phosphodiester linkage, we i

32 combination with a continuous roll of film (in lieu of a static platform), enabling the rapidly perm

33 combination of catalyst and substrate graphs in lieu of a transition-state model.

34 ylation substrates with the alkynyl reporter in lieu of adenylyl 5'-monophosphate (AMP) allows their

35 guidelines support neoadjuvant chemotherapy in lieu of adjuvant chemotherapy and carboplatin-based r

36 alternative for neonates and infants, either in lieu of allotransplantation or as a bridge until an a

37 athway that may underlie the choice to smoke in lieu of alternative reinforcement during a quit attem

38 In lieu of an actual ballcourt, the focus may have been

39 The use of an alkyne in lieu of an alkene leads to the formation of isoxazole

40 d utilized the maltose binding protein (MBP) in lieu of an antibody in an ELISA.

41 In lieu of an enzyme-linked detection method, we have de

42 not recognized by TFIID and cannot function in lieu of an Inr.

43 ibitors which incorporate P1 lactam moieties in lieu of an L-glutamine residue are described.

44 UPs and could be used in conjunction with or in lieu of ancillary tests and extensive diagnostic work

45 al toolkit approach to evolutionary biology, in lieu of any grand unified theory updated to include m

46 the need to employ data-adaptive methodology in lieu of arbitrary cutoffs to distinguish low expresse

47 expressing a green fluorescent protein (GFP) in lieu of Arf coding sequences allow analysis of Arfpro

48 Finally, the modified protein containing 1 in lieu of Arg26 also bound to the i-motif DNA more stro

49 Glutamate in lieu of Asp278 partially restored activity, whereas a

50 e to utilize NAD+ or ADP to promote ligation in lieu of ATP.

51 t expressed L. monocytogenes rsbR (rsbR(Lm)) in lieu of B. subtilis rsbR (rsbR(Bs)) was created and w

52 isease, and where plasma may be interrogated in lieu of BALF or lung tissue.

53 In lieu of behavioral conditioning, we assessed in vivo

54 r transfer kinetics at a water/oil interface in lieu of biological membranes.

55 died as a means of following stable patients in lieu of biopsy.

56 oped using 3-diethylamino-1-propanol (deapH) in lieu of BnOH and NEt(3).

57 test meals of approximately 140 g tortillas in lieu of breakfast.

58 coronary adenosine infusion (400 microg/min) in lieu of brief ischemia (protocol 2) and were abolishe

59 the expected time between accepted mutations in lieu of calculating log-odds probabilities.

60 he S. pombe or mammalian guanylyltransferase in lieu of Ceg1.

61 within the central memory T cell pool occurs in lieu of cellular proliferation or activation, but wit

62 Pct1p is functional in vivo in S.cerevisiae in lieu of Cet1p, provided that it is coexpressed with t

63 ovorin, and oxaliplatin (FOLFOX) can be used in lieu of chemoradiotherapy is uncertain.

64 In lieu of chiasmata and synaptonemal complexes, there m

65 h enables extracted IM peak areas to be used in lieu of chromatographic peak areas.

66 limitations, biomedical articles may be used in lieu of clinical reports to represent the semantics o

67 se whole exome sequencing in addition to, or in lieu of, clinically available sequencing gene panels.

68 te, these signal strength values can be used in lieu of confirmatory testing with TP-PA and FTA-ABS.

69 In lieu of continuous time active feedback control in co

70 ed serving as a flexible analytical platform in lieu of conventional attenuated total reflection (ATR

71 odynamic binding data in a label-free manner in lieu of conventional isotherm studies, especially whe

72 allopian tubes (opportunistic salpingectomy) in lieu of conventional methods of tubal sterilization h

73 uses 3D endoscopy and SLAM-based algorithms in lieu of conventional optical or electromagnetic track

74 ce cisternae of smooth endoplasmic reticulum in lieu of conventional synapses.

75 les regeneration using low-temperature steam in lieu of costly pressure or temperature swings.

76 CT suggests that ZTE may be used clinically in lieu of CT in some cases.

77 patient-specific bladder tissue regeneration in lieu of current enterocystoplasty procedures and have

78 In this review, the authors propose in lieu of current evidence that it is reasonable to ree

79 P phosphodiesterase by introducing histidine in lieu of Cys(74).

80 ceptor 4-aminobenzo[g]quinazoline-2-one (Cf) in lieu of cytidine22 in the i-motif DNA.

81 In lieu of data from completed randomized trials, indica

82 om the cytoplasm of the eukaryotic host cell in lieu of de novo synthesis, an evolutionary outcome un

83 P. annua emergence is most rapidly changing in lieu of developing models to predict when specific em

84 mand for developing descriptors or features, in lieu of DFT, to accurately predict catalytic properti

85 g the division process remains controversial in lieu of direct data.

86 r expert is employed for supervised training in lieu of direct observations, which are not available.

87 potential use of novel anti-PD1/PDL1 agents in lieu of DLI.

88 s for couples with disease-causing mutations in lieu of embryo selection.

89 ynthesize metallic nitride fullerenes (MNFs) in lieu of empty-cage fullerenes (e.g., C60, C70) withou

90 Chronic kidney disease was used in lieu of end-stage renal disease.

91 uld be used in low-risk Barrett's oesophagus in lieu of endoscopy.

92 to carry out a specific biochemical function in lieu of engineering a single microbe to do the same t

93 ole of the AHR in obesity and fat metabolism in lieu of exogenous toxicants.

94 ascular at 2 weeks and exhibited blood lakes in lieu of extensive vessels at later time points.

95 ctive site can use a few amino acid residues in lieu of extra domains to accommodate chemically disti

96 soil mass (ESM) method has been recommended in lieu of FD for assessing changes in SOC stocks in min

97 entifying mechanisms to promote regeneration in lieu of fibrosis and scarring.

98 However, in lieu of fostering their refolding, Aha1 allows ubiqui

99 ls can be used for the normal mode searching in lieu of fully atomic models with little loss of overa

100 ed mating as a premating isolating mechanism in lieu of geographic barriers to gene flow.

101 ursors could be manipulated to repair myelin in lieu of glial transplantation.

102 otrimeric G protein activation that operates in lieu of GPCRs.

103 ohesion could be used as an objective metric in lieu of 'ground truth' to evaluate the quality of pro

104 er, the term cardiac activity is recommended in lieu of 'heart motion' or 'heartbeat.' The terms 'liv

105 effect of astrocyte-conditioned medium (ACM) in lieu of HFA to study the role of secreted factor(s) o

106 In lieu of high-resolution structural information, estab

107 the 2-oxo substituents were also introduced in lieu of His24.

108 itron emission tomography should not be used in lieu of histology to diagnose sarcomas, but may aid i

109 g data-driven reconstructions of soundscapes in lieu of historical recordings, here we quantify chang

110 Endonuclease inhibition promotes NHEJ in lieu of HR, while exonuclease inhibition confers a re

111 antigen-catalyzed unwinding of SV40 origins in lieu of HSSB but inhibits both RNA primer synthesis a

112 e generates stoichiometric hydrogen peroxide in lieu of hydroxyornithine.

113 ansitioned to a less intensive level of care in lieu of ICU admission while still in the emergency de

114 city (using mice transgenic for human HLA-A2 in lieu of immunizing humans) were analyzed to define pe

115 Used in lieu of immunosuppressive corticosteroids, the angiot

116 6) Treg per kg at Day +5 posttransplantation in lieu of induction immunosuppression (Treg Therapy coh

117 , we used A. suum pseudocoelomic fluid (PCF) in lieu of infection to define molecular mechanisms of a

118 fic mRNA degradation steps in addition to or in lieu of inhibiting translation initiation.

119 re with virtual monitoring and clinic visits in lieu of inpatient or in-home care.

120 individual histologic features were analyzed in lieu of INPC.

121 Additionally, in lieu of isolation, the aryl iodide solutions were use

122 ms prior to accessing the medical system (or in lieu of it).

123 horylate and activate certain STAT proteins, in lieu of JAK kinases.

124 Vaccination strategies in lieu of kidney grafts failed to convert mixed chimeri

125 plication of one such molecule, kenpaullone, in lieu of Klf4 gave rise to iPS cells that are indistin

126 pecifically induces pEtN addition to lipid A in lieu of L-Ara4N when Zn2+ is present.

127 rrespondence between whole triangular meshes in lieu of landmark configurations.

128 drenalectomy will be increasingly considered in lieu of laparoscopic adrenalectomy as robotic systems

129 lly, we introduced CalphaMe-leucine residues in lieu of leucine at positions 14, 15, 19, 27, and 37 i

130 medications in combination with, rather than in lieu of, lifestyle modification.

131 administration of macrocyclic GBCA chelates in lieu of linear chelates.

132 scars, and photographs may reliably be used in lieu of live patient assessments.

133 assess the reliability of using photographs in lieu of live patient scar rating assessments, and to

134 nsiderations for adopting non-invasive tests in lieu of liver histology as an RLSE in drug developmen

135 ) has renewed interest in sublobar resection in lieu of lobectomy.

136 l classes of compounds with desired activity in lieu of lone compounds.

137 duction of the apolar amino acids Ala or Leu in lieu of Lys84 in concert with the deletion of 11 C-te

138 In lieu of MDSCs, KCR animals at comparable time points

139 ich are not subject to regulatory oversight, in lieu of medical consultation can delay the diagnosis

140 that cooperated with activated beta-catenin in lieu of MET.

141 logue containing allylglycine at position 84 in lieu of methionine.

142 changes that up-regulate aerobic glycolysis in lieu of mitochondrial respiration for energy producti

143 urden and trends in the American population, in lieu of more costly clinical periodontal examinations

144 A control group received only saline in lieu of morphine.

145 -diol-t-epoxide), using cumene hydroperoxide in lieu of NADPH/O(2).

146 hetic peptides could be used in a QCM assay, in lieu of native or recombinant antigens or capture ant

147 ium current in the primitive heart and brain in lieu of Nav1-type sodium channels and to substitute f

148 pathological neovascular tufts often emerge in lieu of needed physiological revascularization.

149 In lieu of new muscle synthesis, the human heart replace

150 nitroethane was used as a nucleophile source in lieu of nitromethane, a mixture of ( E)- and ( Z)-iso

151 educed; that is, they functioned as oxidants in lieu of O(2).

152 In lieu of on-board enzymatic activity these receptors r

153 Maintenance therapy was given in lieu of or after DI, with total duration of therapy a

154 ll of the services provided by the practice, in lieu of or in addition to traditional insurance arran

155 phenology is suggested where cold hardiness in lieu of (or in addition to) budbreak is used.

156 ffect the variance of the quantitative trait in lieu of, or in addition to, affecting the trait mean.

157 This term is advocated in lieu of other proposed nomenclature that presumes a c

158 ent of a respiratory chain that utilizes N2O in lieu of oxygen.

159 (iii) Formulated hypotheses were: first, in lieu of Pearson's correlation, an augmented, composit

160 Thus, PET/MRI could be used in lieu of PET/CT if this approach becomes economically

161 Alanine in lieu of Phe-310 inactivated Cet1p, whereas Tyr or Leu

162 d dark food chains rely upon chemoautotrophy in lieu of photosynthesis, with primary production based

163 PIC, and by delivering recombinant cytokines in lieu of PIC.

164 Analogues incorporating pyrrolidine in lieu of piperidine were also prepared.

165 increased odds of unplanned valve procedure in lieu of planned isolated CABG (adjusted odds ratio: 4

166 ved for difficult cases or before thymectomy in lieu of plasma exchange.

167 tus and could be used as proxies of exposure in lieu of pollutant measurements, hence these variables

168 6.9) for the first 2 minutes of reperfusion in lieu of postconditioning caused equivalent cardioprot

169 e-fixed material stabilized with tannic acid in lieu of postfixation with osmium tetroxide.

170 tissue at the protein level and may be used in lieu of procedures such as BAE.

171 speculated to provide progestational support in lieu of progesterone itself.

172 ampling strategy for reducing database size, in lieu of property-based filters.

173 se in food antigen-specific T helper 2 cells in lieu of pT(reg) cells, leading to compromised toleran

174 required before this technology can be used in lieu of quality-controlled standard assays.

175 otherapy more extensively in addition to and in lieu of radiotherapy to improve survival for tumors s

176 pid dimerization (k = 5 x 10(9) M(-1) s(-1)) in lieu of reacting with O2 or autoxidizable substrates.

177 ures available, VALERIE displays PSI values, in lieu of read coverage, which is more suitable for rep

178 s of ligand properties and target activities in lieu of receptor structure.

179 fects were identified using matched analyses in lieu of regression.

180 atio values above a cutoff value can be used in lieu of repeat treponemal tests.

181 e being referred for cardiac transplantation in lieu of revascularization surgery.

182 rhombomere X (an aberrant segment that forms in lieu of rhombomeres 5 and 6).

183 Nonetheless, EcFcp1 can function in lieu of Saccharomyces cerevisiae Fcp1 to sustain yeas

184 , the descriptor 'associated' should be used in lieu of 'secondary' for Sjogren disease occurring in

185 gs; and 4Ac, with Glu(3) and Asp(4) inserted in lieu of Ser(3).

186 In lieu of Smac translocation as seen in other paradigms

187 stures via adjustments of the limbs and tail in lieu of specialized control surfaces.

188 ntravenously with intervals of up to 4 weeks in lieu of standard immunosuppressive therapy, appeared

189 ropose that psychiatric intervention be used in lieu of standard medical care, but as one of its inte

190 n of the health importance of drinking water in lieu of sugar-sweetened beverages, have raised intere

191 d thus, formation and dissociation energies (in lieu of surface energy), Ostwald ripening is not supp

192 ient population, where patients receive SABR in lieu of systemic therapy, one-in-three patients are a

193 lymersomes modulate antigen presenting cells in lieu of T cells, significantly improving maintenance

194 The protection from Httex1 aggregation in lieu of TDP43-LCD aggregation is interesting, as it m

195 hat the latter requirement could be bypassed in lieu of that tendered by noncognate B cells.

196 nds is their acyclic dimethyl ether backbone in lieu of the (isopropylidene) acetal moiety characteri

197 e design of four new analogues of 1 bearing, in lieu of the 2,6-dimethoxyphenoxy residue, a 6-methoxy

198 electivity, including several with a halogen in lieu of the 4'-OH in the daunosamine sugar, one compo

199 rack extends upstream from the P(6) position in lieu of the acidic residue present in viral substrate

200 topoisomerase containing serine or threonine in lieu of the active site Tyr-274 form no detectable co

201 Introducing alanine in lieu of the adenine-binding "Q motif" glutamine (Gln2

202 autosome pair becomes a sex chromosome pair in lieu of the ancestral sex chromosomes.

203 t limits of detection (LODs) are compromised in lieu of the best sputtering crater shapes for depth r

204 , including an anomalous singlet at 853 cm-1 in lieu of the canonical Fermi doublet (850/830 cm-1) fo

205 l Ala) and peptide 5, containing a PEG block in lieu of the central turn, were similar to peptide 4 i

206 ture in the tadpole epidermis that functions in lieu of the cornified, stratified epithelium of the a

207 ure of hPOT1 bound to DNA with a ribouridine in lieu of the critical deoxythymidine and show that thi

208 ic B subunit of ETEC heat-labile toxin (LTB) in lieu of the CTB pentamer and a donor strand truncatio

209 suggests MSLN may provide clinical diagnosis in lieu of the current approaches that require invasive

210 t inspection form in Kenyan slaughterhouses, in lieu of the currently used paper-based format.

211 ompound containing a truncated lactol moiety in lieu of the cyclitol, were prepared.

212 In lieu of the detrimental effects of atrazine on enviro

213 lone or benzo[d]isothiazolone core structure in lieu of the dimethylpyridine-fused isothiazolone moie

214 heir different disulfide bond structure and, in lieu of the disintegrins' signature Arg-Gly-Asp (RGD)

215 n the budding yeast Saccharomyces cerevisiae in lieu of the endogenous fungal triphosphatase (Cet1p)

216 ive in vitro and functional in vivo in yeast in lieu of the endogenous guanylyltransferase Ceg1; (iii

217 function in vivo in Saccharomyces cerevisiae in lieu of the essential cellular cap methyltransferase

218 ase known; it suffices for yeast cell growth in lieu of the essential yeast DNA ligase Cdc9.

219 o sustain growth of Saccharomyces cerevisiae in lieu of the essential yeast ligase Cdc9, but LigB, Li

220 that this platform can successfully be used in lieu of the flow system while also decreasing the tim

221 e.g., dedicated quantum cascade lasers (QCL) in lieu of the FT-IR spectrometer, the developed sensing

222 ures a sparse but representative data subset in lieu of the full dataset.

223 and if other titratable amino acid residues in lieu of the histidines could bind protons and how the

224 ridge to K212 and a hydrogen bond with T213, in lieu of the interaction with an arginine side chain f

225 e from Baird 4npi aromaticity of compounds 7 in lieu of the intrinsic Huckel (4n + 2)pi aromaticity a

226 hore segment that both imparts lipophilicity in lieu of the isoprenyl tail of ubiquinone, and reports

227 In lieu of the limited cell source for treating skeletal

228 CALGB 9511 used pegaspargase (PEG-ASP) in lieu of the native enzyme.

229 light applicators, we utilized an endoscope in lieu of the optical fiber to monitor motion in the fi

230 In lieu of the over-oxidation dilemma, the high stabilit

231 um Bayes factor is objective and can be used in lieu of the P value as a measure of the evidential st

232 In lieu of the pleiotropic effect of CD8alpha(+) DCs in

233 stionnaire for the diagnosis of fibromyalgia in lieu of the previously required tender point examinat

234 12-13 nor introduction of a carbamide moiety in lieu of the side chain of Ser7 led to CRF antagonists

235 lating liposomes for signal enhancement used in lieu of the single fluorophore-labeled probe in order

236 equations (BIA average method) could be used in lieu of the skinfold method for categorizing subjects

237 y introduction of a molecular synthon -O-CO- in lieu of the supramolecular synthon Br...Br in the pre

238 are missing as they use similarity matrices in lieu of the trees.

239 show that installing a canonical Met ligand in lieu of the Tyr found at the heme of MauG associated

240 In lieu of the unsatisfactory nitration, a regioselectiv

241 nm with relatively strong emission develops in lieu of the violet absorption.

242 "reset" yeast to use core human nucleosomes in lieu of their own (a rare event taking 20 days), whic

243 unctional) splice sites are selectively used in lieu of these cryptic sites has remained unexplored.

244 In lieu of this evidence, we discuss the potential of ta

245 In lieu of this, we developed routines in MATLAB (The Ma

246 In lieu of this, we discuss alternative approaches for c

247 In lieu of this, we used Wolbachia densities in mosquito

248 final arbiter after an extensive evaluation in lieu of tissue biopsy.

249 In lieu of tissue samples, we measured cytokines, inflam

250 Corneal injury rates (in lieu of total number of events) were utilized to acco

251 t is most important to use dioxygen directly in lieu of toxic and/or corrosive stoichiometric oxidant

252 bacterium, Zymomonas mobilis, can use N2 gas in lieu of traditional nitrogen supplements.

253 ngines through utilizing oxygenated biofuels in lieu of traditional nonoxygenated feedstocks.

254 In lieu of traditional pharmaceutics and invasive therap

255 With the increasing use of hydroxyurea, in lieu of transfusion therapy, for SCD patients with ab

256 , the issue of permanent device implantation in lieu of transplantation could be addressed through th

257 e benefits and limitations of device support in lieu of transplantation.

258 ld promise for diagnostic use in the abdomen in lieu of true unenhanced (TUE) images.

259 now considered for permanent contraception (in lieu of tubal ligation) or ovarian cancer prevention

260 0% [0 of 193]; 95% CI: 0, 2) with use of VUE in lieu of TUE images.

261 2)O(2), UV-A radiation, or high irradiance), in lieu of turbulence, caused comparable ROS accumulatio

262 analogue, containing two carbazole subunits in lieu of two of the four acetone bridging elements nor

263 containing glutamate, cysteine or histidine in lieu of Tyr-274 catalyze endonucleolytic cleavage of

264 y, intravenous proton pump inhibitor therapy in lieu of vasoconstrictors achieved similar hemostatic

265 sting, increased reliance on OOI technology, in lieu of VF testing, may be detrimental to patient car

266 In lieu of viable eco-friendly synthesis pathways, conve

267 of visceral fat by computed tomography scan (in lieu of waist circumference).

268 e that express non-signalling CD3zeta chains in lieu of wild-type CD3zeta.

269 and stimulatory vD12 subunits) can function in lieu of yeast Abd1.

270 amino acid Arabidopsis RNA ligase functions in lieu of yeast Trl1 in vivo and identify essential sid

271 opose the name of NatA (N-acyltransferase A) in lieu of YiaC to reflect the function of the enzyme.

272 SODs to control catalysis and copper binding in lieu of zinc and the ESL.

273 ain the active site and orient the substrate in lieu of Zn binding, representing a significant depart