1 map the site-binding energetics of Syt1 both
in the absence and presence of Ca(2+).
2 human processive Pol delta-DNA-PCNA complex
in the absence and presence of FEN1.
3 Presentation of the familiar context, both
in the absence and presence of the social stimulus, stro
4 isible-light irradiation at room temperature
in the absence of a catalyst.
5 reductive elimination at benzylic positions
in the absence of a cocatalytic Lewis acid.
6 However,
in the absence of a complete molecular understanding of
7 r more interest from the research community,
in the absence of a concerted effort to study genes in a
8 In the absence of a correlate(s) of protection against h
9 h compartmentalize molecules intracellularly
in the absence of a lipid membrane.
10 tion in the human host have remained elusive
in the absence of a model for the viral entry site.
11 In the absence of a pharmacological cure, finding the mo
12 chitecture, synthesize such C-terminal tails
in the absence of a small ribosomal subunit and mRNA has
13 of elevating their firing for long durations
in the absence of a stimulus.
14 In the absence of a universal influenza A vaccine or tre
15 In the absence of AC6, activation of AMPK mobilizes Kif1
16 In the absence of ACE2, single-RBD-up conformations domi
17 den cardiac arrest is common, occurring even
in the absence of acute coronary artery occlusion, and c
18 onstrate that changes-of-mind can occur even
in the absence of additional evidence after the initial
19 creases in social (acoustic) cues of density
in the absence of additional food can induce similar lif
20 paired helical filament-like fibres in vitro
in the absence of additives such as heparin.
21 While the 'humanized' yeast grew
in the absence of adenine, it did so poorly.
22 ociated adipose tissue had ongoing lipolysis
in the absence of adipocyte triglyceride lipase (ATGL).
23 ic persistence, but persister cells can form
in the absence of all hipBA operons or spoT, indicating
24 and allergic responses can be triggered even
in the absence of allergens due to Pavlovian conditionin
25 d leukemia progression was severely impaired
in the absence of AMD1 in vivo.
26 In the absence of an effective treatment, direct cell tr
27 ction was present beginning at ~110 ms, even
in the absence of an explicit task to think about the re
28 te is achieved when G(s) is coupled to GPR52
in the absence of an external agonist.
29 on posterior segment examination or imaging
in the absence of anterior segment inflammation.
30 In the absence of anti-EBV agents, however, therapeutic
31 of CD8 T-cell responses during HIV infection
in the absence of antiretroviral treatment, we compared
32 translocation and GSK-3beta phosphorylation
in the absence of AnxA8.
33 innitus is the conscious perception of sound
in the absence of any acoustic source.
34 ts own, this sequence targeted to microvilli
in the absence of any direct interaction with the other
35 f mTORC1, and prevented activation of mTORC1
in the absence of any effect on Smad 2/3 phosphorylation
36 d the medial geniculate body of the thalamus
in the absence of any explicit behavioural task.
37 hereas this reaction with secondary alcohols
in the absence of any external oxidants furnished the te
38 cles show basal JAK-STAT signalling activity
in the absence of any immune challenge.
39 configuration with gas-permeable walls, but
in the absence of any installed source of gas.
40 an also be active during action observation,
in the absence of any movement.
41 may represent a suitable therapeutic option
in the absence of any other therapeutic approaches.
42 essant-like (AD-like) effect of R,S-ketamine
in the absence of any psychotomimetic or abuse-related e
43 rode's chronocoulometric responses at 0.3 V,
in the absence of any redox indicators, allowed a single
44 s can be reproduced in artificial conditions
in the absence of any specific cross-linking proteins, w
45 ternative sigma factor sigma(I) is essential
in the absence of aPBPs.
46 electro-optics to visualize the appearance,
in the absence of applied field, of a permanent electric
47 In the absence of approved vaccines and therapeutics for
48 RG ligands and has an equilibrium population
in the absence of ARG that is below detection limit.
49 d a cardiovascular benefit from fibrate even
in the absence of atherogenic dyslipidemia.
50 In the absence of autoantibodies, an incompatible crossm
51 cal evidence of complex cognitive processing
in the absence of awareness, raising questions about the
52 mphoid cell (ILC2) responses are exaggerated
in the absence of basophils, resulting in increased infl
53 Mechanistically, we found that
in the absence of BD(L), the absolute cell number of CD4
54 ge adipocytes mediated by GABPalpha emerging
in the absence of beta-adrenergic signaling.
55 In the absence of c-di-GMP, ShkA predominantly adopts a
56 fore hypothesized that ODP would be impaired
in the absence of C1q, and that V1b development would al
57 dependent plasticity of V1b is mostly normal
in the absence of C1q, even though C1q has previously be
58 lasticity of the mouse V1b is grossly normal
in the absence of C1q.SIGNIFICANCE STATEMENT These findi
59 first plant that grows photoautotrophically
in the absence of carotenes: a tobacco plant containing
60 s are integrated in a functional orientation
in the absence of Cas4 is not known.
61 In the absence of caspase-8, another of its paralogs, ca
62 astructure showed that AZ size was increased
in the absence of CAST/ELKS.
63 However, control of lymphoma remained intact
in the absence of CD4 T cells.
64 cells elicit an impaired antitumor response
in the absence of cDC1s.
65 We further suggest that VDAC can occur
in the absence of changes in early visual processing in
66 ecome more prominent as AMR can be diagnosed
in the absence of circulating DSA.
67 evidence that NAFLD-associated HCC may arise
in the absence of cirrhosis, is often diagnosed at advan
68 idobacterium and body composition); however,
in the absence of clear microbiome-driven effects, cauti
69 an one nut is frequent, and co-sensitization
in the absence of clinical data is often obtained.
70 pes, and abnormal echocardiographic measures
in the absence of clinical HF was assessed.
71 oles to restrain B cell responses to antigen
in the absence of co-stimulation and do so, in part, by
72 supports the judicious use of blood cultures
in the absence of compelling evidence for bacterial coin
73 indicate that social selectivity can emerge
in the absence of complex future-oriented cognition, and
74 is the alleged destabilization of complex I
in the absence of complex III.
75 ents, and (7) role of adjunctive antibiotics
in the absence of confirmed infections.
76 w free energy barrier to partial dehydration
in the absence of conformational change indicates Kir ch
77 on matrix that measures the potential spread
in the absence of containment interventions.
78 In the absence of contemporary, population-based epidemi
79 that suggest that persistence of cancer risk
in the absence of continued carcinogen exposures is simp
80 In the absence of controlled trials, treatment of neonat
81 n polymerization is induced on bead surfaces
in the absence of CP, we produce robust polarized actin
82 ability to maintain polarized network growth
in the absence of CP.
83 Inefficient secretory trafficking of ATZ
in the absence of CRT is coincident with enhanced accumu
84 ceptor (CSF1R), but some macrophages persist
in the absence of CSF1R.
85 across a range of acute healthcare settings
in the absence of cultured virus underlines the potentia
86 at arrestin recruitment can drive locomotion
in the absence of D2R-mediated G protein signaling.
87 However, overactive, relapsing fear behavior
in the absence of danger is a hallmark of disabling anxi
88 We show that
in the absence of Dcc, some ganglion cell axons stalled
89 Normal aging,
in the absence of dementia, also results in gradual cogn
90 at peripheral neuropathy (PN) is common even
in the absence of diabetes.
91 How do we learn
in the absence of direct experience?
92 is replicates to high numbers in the airways
in the absence of disease symptoms or notable inflammato
93 In the absence of disorder, it has long been expected th
94 In the absence of Dna2, 5'-flaps are thought to accumula
95 nical macroautophagy machinery and can occur
in the absence of double-membrane lipoautophagosomes.
96 In the absence of drugs approved by regulatory agencies,
97 In the absence of DXO1 function, transcripts displaying
98 regulation in dystrophin gene transcription
in the absence of dystrophin gene excision.
99 In the absence of E-cadherin-mediated cell adhesion, LC
100 fined as a ratio of the binding of substrate
in the absence of effector to the binding of the substra
101 In the absence of EGFR-mediated phosphorylation, STING r
102 [CI]: 1.48-3.03), with stronger associations
in the absence of eLAP (HR = 2.87; 95% CI: 1.83-4.49) th
103 Patients with PH
in the absence of eLAP are at high risk of death and in
104 sufficient to accelerate tumorigenesis, even
in the absence of endogenous PD-L1; (3) PD-L1(+) T cells
105 t1 expression and trafficking when expressed
in the absence of endogenous SV2A (to mimic the homozygo
106 In the absence of enzymatic activity, increase in the TR
107 In the absence of epicardial coronary artery disease, pa
108 We conclude that
in the absence of epidemiological data, our catalogue of
109 Impaired Treg suppression
in the absence of ERbeta was associated with aberrant ov
110 In the absence of evidence of clinical superiority of ex
111 In the absence of EXO1, forks accumulate at stabilized G
112 the overlying epithelial cancerization field
in the absence of exogenous carcinogens or promoters req
113 F4-GIF1 induced efficient wheat regeneration
in the absence of exogenous cytokinins, which facilitate
114 During the electroless process (i.e.,
in the absence of external electrical power), the open c
115 we find ESCs exhibit intrinsic heterogeneity
in the absence of external gradients by forming intercon
116 neural pathways promoting preference change
in the absence of external reinforcements.
117 In the absence of FAO, the progenitors are unable to dif
118 In the absence of fertilization, fungal and total eukary
119 together with Activin maintain self-renewal
in the absence of fibroblast growth factor (FGF) signall
120 can rescue iMEF survival and snRNP assembly
in the absence of flwt-Smn, indicating exon 2B is not re
121 t is desirable for mechanophores to be inert
in the absence of force but highly reactive under applie
122 Furthermore,
in the absence of four SPA genes, the pivotal transcript
123 Even
in the absence of fully established risk prediction sche
124 They can promote viral replication
in the absence of FXR-HVD interactions albeit less effic
125 respiration/function, and mRNA export occurs
in the absence of Fzo1, which is required for mitochondr
126 Finally, we show that
in the absence of galectin-8, pericentrin compactness is
127 In the absence of gangliosides, both virion types are ef
128 ability to lower circulating glucose levels
in the absence of GDF15 activity.
129 edly reduced plasma levels of BMP9 and BMP10
in the absence of GDF2 mutations.Conclusions: Our findin
130 llowing selective TKI pressure, which occurs
in the absence of genetic mutations.
131 and activate programmed cell death pathways,
in the absence of glucose.
132 is feature allows iNKT cells to respond even
in the absence of glycolipid Ags, for example, during vi
133 tory finding with little clinical importance
in the absence of gout or kidney stones.
134 e nucleus results in nuclear mTORC1 activity
in the absence of growth factor stimulation.
135 ed to ensure ongoing protein quality control
in the absence of growth.
136 Clinicians, eager to offer the best care
in the absence of guiding data, have provided patients w
137 oreover, pursuit classification is far worse
in the absence of head movement information.
138 a role in maintaining sequence conservation
in the absence of homologous recombination.
139 esults show that sunk cost effects can arise
in the absence of human-unique factors and may emerge, i
140 energy intake during lunch and in an eating
in the absence of hunger task.
141 Intracellular glutamine levels are decreased
in the absence of HUWE1 and may contribute to MYC degrad
142 ndrome coronavirus 2 infected patients, even
in the absence of hypoxia.
143 mune system and persistent BDG antigenaemia,
in the absence of IFD, can result in deleterious pro-inf
144 indings support that early changes occurring
in the absence of IL-10 may lead to better bacterial con
145 ependent eosinophil influx in immune control
in the absence of IL-4/IL-13-dependent immune mechanisms
146 mune responses to the desired target region,
in the absence of immune interference by other epitopes.
147 that the majority of LVS remained cytosolic
in the absence of immune pressure, eventually resulting
148 xpanded after transplantation (1.7-4.6-fold)
in the absence of immunosuppression, homed to allografts
149 prevent, rather than promote, MIDAS docking
in the absence of inducing signals.
150 However, direct delivery of LOS to cells
in the absence of infection did not alter antigenic pept
151 General host vigour
in the absence of infection was also correlated with hos
152 , and allergen-induced MC degranulation even
in the absence of inflammatory environment.
153 ht touch, pinprick, and thermal hyperalgesia
in the absence of injury, without associated changes in
154 rprisingly, they are also actively repressed
in the absence of injury.
155 In the absence of its ligand TNFalpha, TNFR1 assembled i
156 ting genes, Shot knockdown induces apoptosis
in the absence of Jun kinase (JNK) activation, but inste
157 ant barriers to implementation, particularly
in the absence of known human immunodeficiency virus (HI
158 XoxF1 and XoxF1 D320A, when produced
in the absence of La(3+), coordinated Ca(2+) but exhibit
159 The model predicted that
in the absence of lateral inhibition, two-dimensional rh
160 In the absence of LGP2, MDA5-mediated activation of type
161 ranslational regulation is presented whereby
in the absence of ligand the riboswitch is largely unfol
162 s to recapitulate photoredox-like reactivity
in the absence of light across a wide range of substrate
163 e it as an electron acceptor for respiration
in the absence of light and O(2) .
164 utations can render the receptor active even
in the absence of light.
165 gle point mutations in DHFR are advantageous
in the absence of Lon, but advantageous mutations are la
166 actor 3 (Rapgef3), was strongly up-regulated
in the absence of LRRK2 and down-regulated in its presen
167 Conversely,
in the absence of LRRK2 and Rab8A, damaged endolysosomes
168 o distinct postsynaptic "dyad" partners, but
in the absence of LRRTM4, "monad" and "triad" arrangemen
169 In the absence of lysis, MAC may induce intracellular si
170 We use forecasts made
in the absence of machine models as prior beliefs to qua
171 at with monthly injections for persistent HE
in the absence of macular thickening.
172 and active TGFbeta-1 did not bind fibrillin
in the absence of MAGP-1.
173 scription relative to control, respectively,
in the absence of mammalian readers of DNA methylation.
174 MNT was required for cell proliferation even
in the absence of MAX.
175 Methylotrophs persisted for weeks
in the absence of methane, making them a powerful marker
176 g selection of B cell antigen receptors even
in the absence of microbiota.
177 , transition from G(1) to S phase is blocked
in the absence of Midkine-a, resulting in significantly
178 In the absence of Mitf function, cNCC migration and loca
179 f the GTPase obgE that is synthetically sick
in the absence of Mla; providing another link between ce
180 ong photochemical transformations of mercury
in the absence of molecular oxygen.
181 iagnosis of severe neonatal cholestasis even
in the absence of more typical features.
182 nerated movement (self-generated touch) than
in the absence of movement (external touch).
183 Single-cell sequencing revealed that
in the absence of murine CD4 T cells, resident microglia
184 mbled, transgene expression can persist even
in the absence of mutations disrupting the silencing pat
185 II MVC-activated enzyme, retaining activity
in the absence of MVCs.
186 oor immune reconstitution have been observed
in the absence of myeloablation.
187 onal framework that explains changes-of-mind
in the absence of new post-decision evidence.
188 TrkB reduction, caused by over acidification
in the absence of NHE6.
189 m that holds the structure in an "off" state
in the absence of nitrate signal.
190 tion studies showed neuritis still developed
in the absence of NOD-PerIg CD8(+) T cells but required
191 In the absence of nonreciprocity, the binary fluid mixtu
192 In the absence of obstructive coronary artery disease, i
193 across a range of clinical conditions, even
in the absence of obvious incentive to underperform.
194 eir extracellular domain (ECD) conformations
in the absence of orthosteric ligands, which has limited
195 nosmia and ageusia are common, and can occur
in the absence of other clinical features.
196 lated maternal hepcidin excess on pregnancy,
in the absence of other confounding effects of inflammat
197 s well as STAT3 phosphorylation, was reduced
in the absence of P2y(2)r.
198 tion of mevalonate pathway enzyme expression
in the absence of p53 was mediated by accumulation and s
199 are maintained at a subset of Pax7 enhancers
in the absence of Pax7.
200 class I molecule HLA-A*02:01 that is stable
in the absence of peptide and can readily exchange cogna
201 explained by reduced affinity to BMAL1/CLOCK
in the absence of PER2 compared with CRY1.
202 In the absence of perforin, we show that GrB enzymatic a
203 actor was not sufficient for PLE replication
in the absence of phage.
204 It has been shown previously that
in the absence of phosphatase, CaMKII monomers integrate
205 Using EM analysis, we demonstrate that
in the absence of phosphorylated AMELX, KI enamel lacks
206 In FXII-HAE patients, cHK levels,
in the absence of PIC, were significantly higher than in
207 tail (PIC), but they significantly increased
in the absence of PIC.
208 Moreover,
in the absence of Pob3, the FACT Spt16 subunit controls
209 In the absence of policy actions, we estimate that early
210 In the absence of population-wide restrictions, isolatio
211 mosomes have aligned and enter into anaphase
in the absence of PP1 activity.
212 the background incidence of HIV in the trial
in the absence of PrEP, possibly augmented by external d
213 ion in patients with end-stage liver disease
in the absence of prior heart disease.
214 In the absence of proper guidelines and algorithms, avai
215 In the absence of protein contacts, oxoA:G forms a wobbl
216 we observed that the levels of gC are lower
in the absence of pUL47.
217 ith poly(I:C) inducing alloimmunization even
in the absence of recipient type I IFN receptors.
218 tive decline becomes a growing concern, even
in the absence of recognizable neurodegenerative disease
219 racy of an analytical method can be assessed
in the absence of reference standards in silico if the m
220 istence of these cells with donor leukocytes
in the absence of rejection.
221 care experiences in hospital may be negative
in the absence of relational work by nurses to maintain
222 eve long-term therapeutic protein expression
in the absence of repeated administration of pharmacolog
223 a separate task by presenting these stimuli
in the absence of reward contingency and probing their e
224 In the absence of reward, there was either no change in
225 n, these structural constraints are relieved
in the absence of RNA secondary structure.
226 In the absence of RNA, Nterm remained disordered regardl
227 duction of IL-17A and -F from CD4(+) T cells
in the absence of S100A8 and S100A9, as well as increase
228 In the absence of S533 phosphorylation, it was proposed
229 that sustained spatial attention alone, even
in the absence of saccade planning or a spatial cue, is
230 Even
in the absence of sea-level rise, deltas are increasingl
231 n particular, local SMXL5 deficiency results
in the absence of secondary phloem.
232 unlikely to bring about long-term divergence
in the absence of selection.
233 ns of genetic variation in populations, even
in the absence of selection.
234 ggesting a reversal of P450-based resistance
in the absence of selection.
235 facilitate rapid phenotypic divergence even
in the absence of selective processes.
236 es remains robustly targeted to the lysosome
in the absence of several core ATGs, including the LC3 l
237 bacteriuria occurs, irrespective of pyuria,
in the absence of signs or symptoms of a urinary tract i
238 The use of UHPH sterilization
in the absence of SO(2) has been used to eliminate wild
239 s (POA(PAG) neurons) elicited USV production
in the absence of social cues.
240 articles (AuNPs), stable against dissolution
in the absence of specific ligands, were added weekly to
241 viduals would have to face to acquire skills
in the absence of specific socio-cognitive abilities.
242 In the absence of SPRY1, FGF9, and FGF20, another FGF li
243 Furthermore, we found that
in the absence of SSB, PriA binds exclusively to the for
244 In the absence of STAT1 signaling, however, depletion of
245 sion in symbiotic than aposymbiotic anemones
in the absence of stress suggest that they are important
246 This pathway to survival only occurred
in the absence of strong local stressors.
247 responding uncertainty of a potential effect
in the absence of stronger direct evidence.
248 Critically,
in the absence of STX3, OS proteins such as PRPH2, the P
249 ogy linked to objective measures was minimal
in the absence of subjective reports.
250 In the absence of substrate, Omega undergoes low-probabi
251 ersal capabilities, and the prediction that,
in the absence of subterranean connections, extreme gene
252 compared with what would have been expected
in the absence of such policies.
253 s known about their cell-type-specific roles
in the absence of suitable tools that would allow for fu
254 ew and accelerated approval of certain drugs
in the absence of survival data.
255 How SARS-CoV-2 is able to achieve high titer
in the absence of symptoms remains unclear.
256 iated with impaired growth of children, even
in the absence of symptoms.
257 In the absence of systemic immunosuppression, diabetic r
258 fferential diagnosis of scleral nodules even
in the absence of systemic symptoms.
259 the residual asynchronous release remaining
in the absence of SYT1.
260 ELs are able to preserve an effector program
in the absence of TCR signaling.
261 nt strains lacking gigC have impaired growth
in the absence of the amino acid cysteine and that gigC
262 s may rescue the heparin/protein interaction
in the absence of the canonical binding element.
263 hreat to genome stability and cell viability
in the absence of the FA pathway.
264 In the absence of the fork remodeler HLTF, forks fail to
265 ng solely the Delta190-196 C1 PrP construct,
in the absence of the full-length protein, were suscepti
266 e tested the properties of memories acquired
in the absence of the HPC.
267 in the liver, fails to promote liver injury
in the absence of the microbiome in vivo.
268 -driven tumors can grow and metastasize even
in the absence of the oxidative pentose pathway, a main
269 ion domain (USD) that promotes UTX stability
in the absence of the rest of MLL3/4.
270 Reduced disease severity
in the absence of the SOS1 variant suggested its potenti
271 In the absence of the sulfone groups, we discovered that
272 In the absence of these upstream components, NPHP3 is re
273 Yet, sterile protection was achieved
in the absence of this epitope, substantiating the conce
274 hrough nucleotide sanitization by MutTs, and
in the absence of this system, accessory DNA polymerases
275 in vivo more potently than single treatments
in the absence of toxicity.
276 were exploited; (3) the chronology of sites
in the absence of traditionally datable materials; and (
277 rated by tens to hundreds of megabases, even
in the absence of transcription.
278 In the absence of TREX1, the genome alterations induced
279 of the 1D topological edge state of bismuth
in the absence of TRS, where backscattering is predicted
280 sted that ribosomes bypass tryptophan codons
in the absence of tryptophan.
281 sors that result in anthocyanin accumulation
in the absence of TT19.
282 Of note, necroptosis occurred only
in the absence of TTP and was mediated by the expression
283 toplankton cells can form at high rates also
in the absence of turbulence.
284 round Cardiac involvement in liver cirrhosis
in the absence of underlying cardiac disease is termed c
285 s in cyclosporine A (CsA)-treated mice, even
in the absence of UV light.
286 otential approaches that could be considered
in the absence of validated strategies.
287 In the absence of VHL, Th17 cells had decreased activati
288 In the absence of Vimentin, pluripotent embryonic stem c
289 sociated with electrogram fractionation even
in the absence of voltage abnormalities.
290 tive mechanisms and insulin resistance, even
in the absence of weight gain.
291 Ectopically targeting E3 to membranes
in the absence of WIPI2 is insufficient to support LC3 l
292 cells caused strongly reduced rosette growth
in the absence of wounding.
293 In the absence of WRN, the expanded TA-dinucleotide repe
294 ity of any single IOL implantation technique
in the absence of zonular support.
295 myocardial structure and function that occur
in the absence of, or in addition to, well-established c
296 H(+) efflux were measured from pH 5.0 to 9.0
in the absence or presence of a membrane potential (Delt
297 ied the interaction of PT with VC1 and sRAGE
in the absence or presence of calcium that acted as a co
298 s of PDIA6-deficient bone marrow cells, both
in the absence or presence of competition.
299 ompleted this task in two conditions, either
in the absence or presence of distractor auditory tones.
300 NADPH elicited rapid formation of diformazan
in the absence or presence of paraformaldehyde, (4) addi