ライフサイエンスコーパス: inactivate

1 that mediate fusion, become proteolytically inactivated.

2 c stress was markedly reduced when lon-1 was inactivated.

3 loses its grip on the RNA:DNA hybrid and is inactivated.

4 This effect is reversed when RAP1 is inactivated.

5 Autoantibodies against leucine-rich glioma inactivated 1 (LGI1) are found in patients with limbic e

6 nducted a prospective reciprocal approach to inactivate 13 single or multiple evolutionary conserved

7 Low doses of 1.7 and 1.2 mJ/cm(2) inactivated 99.9% of aerosolized coronavirus 229E and OC

8 plication and sister chromatid cohesion, and inactivated a third, the DNA damage checkpoint.

9 during virus infection and demonstrates that inactivating a dominant viral antagonist, the coronaviru

10 reagents, and UV energies were successful at inactivating a high titer of SARS-CoV-2.

11 e a set of affinity optimized, enzymatically inactivated ACE2 variants that potently block SARS-CoV-2

12 Co-administration of a UV inactivated Ad4 vector with the Ad5-prM-E vaccine led to

13 IDA was superior to IA for inactivating adult worms at all time points.

14 he DNA-binding species with the binding site inactivated and eGFP as a calibration standard among lab

15 li) bacterial pathogens as well as with heat-inactivated and viable fungi (Candida albicans).

16 n the vaccine without the need for purified, inactivated, and calibrated virus reference antigens.

17 ng chromosomal fusion, the neocentromere was inactivated, and the native centromere of the fused chro

18 rate that Adenylate kinase isoenzyme 1 (AK1) inactivates antimetabolites like Cytarabine.

19 Additionally, inactivated antioxidative pathways, increased reactive o

20 Hours later, cells inactivate APC/C(CDH1) and cross the final commitment po

21 he 10 degrees C adapted strains were rapidly inactivated at higher temperatures.

22 Sulfide significantly and reversibly inactivates AtATG4a.

23 Inactivating ATP production, deoxyribonucleotide synthes

24 ents, whereas tension across the centromeres inactivates Aurora B kinase, and PP2A phosphatase dephos

25 ases in a distance-dependent manner, thereby inactivating Aurora B in metaphase.

26 Electric field treatment inactivates bacteria by physically disrupting the integr

27 ic acid (PFA) is an emerging disinfectant to inactivate bacterial and viral microorganisms in wastewa

28 athological sites when mobilized by distinct inactivated bacterial-based stimuli administered subcuta

29 zed L. braziliensis transfectants were photo-inactivated before (Strategy #1) or after (Strategy #2)

30 Inactivated beta(2)-AR (Nb60) molecules are also largely

31 ify genes which are up or down regulated, or inactivated, between multiple conditions, producing a fi

32 iled to induce IFN-gamma production, whereas inactivated Bp induced IFN-gamma production.

33 Inactivated Bp, but not antigens, induced potent IFN-gam

34 Mice were genetically engineered to inactivate BRG1 specifically in the endometrial epitheli

35 ro1), and protein disulfide-isomerase can be inactivated by a feedback inhibition mechanism involving

36 ant plants, in which OsSBEIIb was completely inactivated by abolishing the catalytic center and C-ter

37 oading with L. braziliensis photodynamically inactivated by both strategies, including CD86 expressio

38 Viruses can be inactivated by exposure to heat or bleach, but polioviru

39 atic, but not terminally expressed, KORs are inactivated by norBNI.

40 synthase (GSa) - respectively activated and inactivated by phosphorylation - and their Ca(2+)-depend

41 These molecules are rapidly inactivated by the action of dipeptidyl peptidase IV (DP

42 ransgenic DNA is recognized and then quickly inactivated by the assembly of a repressive chromatin st

43 Host antimicrobial peptides are inactivated by the capsule as it impedes their penetrati

44 mutation (p53HRmut) and wildtype p53 (p53WT) inactivated by the human papillomavirus 16 (HPV16) E6 on

45 ir potential to be rapidly hydrolyzed (i.e., inactivated) by extracellular peptidases during biologic

46 Here we show that repair of the inactivated C16L/B22R gene of MVA enhances replication i

47 lecular insights into how cAMP-PKA signaling inactivates CaMKK2 and reveals a pathway to inhibit CaMK

48 chnologies, we show that pigs with all PERVs inactivated can also be genetically engineered to elimin

49 e-CHACRs efficiently inactivate Cas9 and can drive to completion in cage expe

50 rx/TrxR restored the activity of polysulfide-inactivated caspase-3 in vitro, and TrxR inhibition pote

51 yclin B and securin promotes anaphase entry, inactivating CDK1 and permitting chromosome segregation,

52 Markedly, stress signals in G1 can rapidly inactivate CDK4/6 to return cells to quiescence but with

53 he 2017-2018 influenza season, quadrivalent, inactivated cell-derived influenza vaccine (ccIIV4) vacc

54 oduction blocked growth the fastest, whereas inactivating cell division or outer membrane protein syn

55 ermoautotrophicum-a purely calcium-gated and inactivating channel-in a lipid environment.

56 of this N terminus leads to functionally non-inactivating channels and structures of open states with

57 uces the upregulation of PD-L1 levels, which inactivates cocultured T cells in vitro, compromises ant

58 MSec also similarly inactivates cofilin, but potentiates TNT formation indep

59 aving inhibitory domains of factor H free to inactivate complement C3b deposited on the trypanosome s

60 several structures, including multiple open-inactivated conformations, further indication of a highl

61 +/- 1 nm of 13.9-49.6 mJ cm(-2) efficiently inactivate coronaviruses in an aerosol.

62 firm that UV-C flow reactors can efficiently inactivate coronaviruses through incorporation into HVAC

63 In contrast, protease-inactivated D pteronyssinus had no effect on offspring g

64 mothers exposed to D pteronyssinus, protease-inactivated D pteronyssinus, or to PBS during lactation.

65 with PRSS1WT mice, as well as enzymatically inactivated Dead-PRSS1R122H mice, we unraveled that incr

66 2 that next to its role in RAAS is needed to inactivate des-Arg9 bradykinin, the potent ligand of the

67 sults show that Fe(VI) was more effective in inactivating dispersed FC than MNV.

68 of Cdk1 in ESCs phosphorylate and partially inactivate Dot1l, the H3K79 methyltransferase responsibl

69 ch in ISCs; its de-repression, when Notch is inactivated, drives progenitor cells to differentiate al

70 nally, we show that this circuit is normally inactivated during consumption and food-seeking.

71 ontaining different microbicidal actives for inactivating Ebola virus-Makona strain (EBOV/Mak) on sta

72 addition to providing a new tool for acutely inactivating eIF4E in cells, our computational approach

73 levels are decreased in cells where TP53 is inactivated, either by HPV16 E6, by expression of a domi

74 eal-time mobility behaviors of activated and inactivated endogenous conformers during agonist treatme

75 ctivity (DUBmut) and the other containing an inactivated endoribonuclease (EndoUmut).

76 was achieved by ectopic expression of the GA-inactivating enzyme AtGA2ox2, which is specific for C(19

77 , also called MLL4) is among the most highly inactivated epigenetic modifiers in lung cancer.

78 to efficiently hydrolyze both activated and inactivated esters.

79 Estrogen sulfotransferase (SULT1E1) inactivates estrogen and regulates its metabolic homeost

80 Ninety percent of infectious virus was inactivated every 6.8 minutes in simulated saliva and ev

81 gulates thrombin generation by enzymatically inactivating factors Va and VIIIa.

82 ment midpoint are likely to be activated and inactivated first in each contraction.

83 n and the pathogenesis of Fowler syndrome by inactivating Flvcr2 in mice.

84 JQ1 directly interacted with FOXA1 and inactivated FOXA1 binding to its interacting repressors

85 ltiple adaptive mutations mediated by a gene-inactivating frameshift mechanism during passage of an a

86 enuated vaccinia virus, rapid acquisition of inactivating frameshift mutations occurred.

87 Centrioles must be eliminated or inactivated from the oocyte to ensure that only the two

88 h is likely due to elevated expression of JA inactivating genes.

89 It is largely caused by inactivating germline mutations in the tumour suppressor

90 Our results demonstrate that by inactivating gliomedin, Bmp1/TLD functions as an additio

91 Unexpectedly, when the Mgat4d gene was inactivated globally or conditionally in spermatogonia,

92 ted in an in vitro infection model with heat-inactivated Gram-positive (Staphylococcus aureus) and Gr

93 Netrin-1 induces Fak kinase to inactivate Gsk3alpha/beta and stabilize beta-catenin whi

94 mplies that phosphorylated AKT was unable to inactivate GSK3beta.

95 disease, with hepatic nuclear factor 1alpha-inactivated hepatocellular adenomas being the most commo

96 EDV), and outline an approach of genetically inactivating highly conserved viral factors known to lim

97 a must be employed to identify patients with inactivating, homozygous SMARCA4 missense mutations who

98 Strains with inactivated hsmR or hsmA have increased sensitivity to r

99 signals, for example, invading pathogens can inactivate immune response pathways and evade detection.

100 ch orthopoxvirus species, numerous genes are inactivated in all other members of the genus.

101 ession of ATRX, a protein that is frequently inactivated in ALT tumors.

102 ymes can suppress tumors, but they are often inactivated in human cancers overexpressing inhibitory p

103 ndent tumour suppressors that are frequently inactivated in human cancers, and FOXO3 is the second mo

104 he MC903 model, whereas these cells remained inactivated in OVA sensitization model.

105 n of an actionable target downstream of RB1, inactivated in SCLC and other advanced tumors, could hav

106 itions in RT occured mainly by activating or inactivating individual IZs or occasionally by altering

107 ion rates are not well understood for 2-dose inactivated influenza vaccination (IIV) schedules in aut

108 ecombinant HA vaccine (rHA) and cell-derived inactivated influenza vaccine (IIV) to egg-derived IIVs

109 , comparator-controlled (trivalent high-dose inactivated influenza vaccine [IIV3-HD], or quadrivalent

110 ter-generated randomisation list, to receive inactivated influenza vaccine containing 15 mug of each

111 A regimen of double-dose inactivated influenza vaccine gave slightly greater immu

112 Standard-dose, seasonal, trivalent, inactivated influenza vaccine induces moderate-to-low ha

113 4 weeks after immunization with the seasonal inactivated influenza vaccine, but numbers returned to n

114 016 through 2017-2018, injectable, trivalent inactivated influenza vaccines (IIV3) and a nasal spray,

115 ter IV A(H3N2)v vaccine and several seasonal inactivated influenza vaccines (IIVs) in adults, elderly

116 cells, which are not induced by traditional inactivated influenza vaccines and may provide protectio

117 recommends LAIV4 and injectable, tetravalent inactivated influenza vaccines replacing IIV3.

118 HD-MAPs were coated with a monovalent, split inactivated influenza virus vaccine containing A/Singapo

119 lls were stimulated with soluble antigens or inactivated intact Bp and the presence or absence of blo

120 ered chimeric toxin irreversibly cleaves and inactivates intracellular RAS at low picomolar concentra

121 pic and syngeneic mouse models, silencing or inactivating IRIS in TNBC cells lowered the levels of ci

122 P), and plasma kallikrein (KLKB1) cleave and inactivate it, with the latter cutting within the argini

123 k1 activate PP2A-B55 and high concentrations inactivate it.

124 polarization-activated cation (I (h) ), slow-inactivating K(+), muscarinic K(+), and Ca(2+) L-type.

125 The prototypical member of the receptor-inactivating kappa opioid receptor (KOR) antagonists, no

126 ular signaling mechanisms mediating receptor-inactivating KOR antagonist action and advance medicatio

127 sults provide evidence that photodynamically inactivated L. braziliensis are susceptible to the degra

128 Inactivating LMNB2 in human iPS cell-derived cardiomyocy

129 is due to its enzymatic subunit, RTA, which inactivates mammalian ribosomes with near-perfect effici

130 ffector, termed NleD, a metalloprotease that inactivates MAPKs by specifically cleaving their activat

131 ions (VAH), similar to those in humans given inactivated measles or respiratory syncytial virus vacci

132 wever, only the latter played a causal role: inactivating medial prefrontal cortex before outcome str

133 s (43 degrees C for 25 min), germ cells with inactivated Mgat4d were markedly more sensitive to the e

134 n of 25 amino acids (aa) from the C terminus inactivated MGAT4D-L, but deletion of 20 aa did not.

135 C treatment is a commonly known technique to inactivate microorganisms.

136 We generated mice with an inactivated mIgE-ITT motif and analyzed serum IgE levels

137 J/cm(2), which is sufficient to irreversibly inactivate most common pathogens in water with the turbi

138 ese are enzymes that are highly efficient in inactivating most of the commonly used beta-lactam antib

139 les in synaptic transmission, we genetically inactivated mTORC1 or mTORC2 in cultured mouse glutamate

140 An inactivating mutation (R258Q) in the Sac inositol phosph

141 h RNA sequence downstream of the PTC and the inactivating mutation within the active site of UPF1.

142 Consistent with this, both FBXW7-inactivating mutations and MDM2 upregulation were found

143 We identify that ARID1A inactivating mutations are present at a high frequency i

144 Out of 25 inactivating mutations carried by the F(3) fish, one in

145 The high frequency of multiple inactivating mutations during experimental evolution sim

146 after the acquisition of two independent EDP-inactivating mutations in all classical zoonotic species

147 These results suggest why inactivating mutations in any of the three human genes l

148 Inactivating mutations in BRCA1-associated protein 1 (BA

149 Inactivating mutations in genes encoding cohesin subunit

150 In humans, inactivating mutations in KIF11 are associated with (1)

151 The KLHL14 gene acquires frequent inactivating mutations in mature B cell malignancies, es

152 as to why both enzymatically activating and inactivating mutations in PTPN11 result in human develop

153 SCCOHT tumors have inactivating mutations in SMARCA4 (BRG1), one of the two

154 ss B7-H3/CD276 that does not result from the inactivating mutations in SMARCB1 (refs.

155 Inactivating mutations in the copper transporter Atp7b r

156 villus inclusion disease (MVID) is caused by inactivating mutations in the myosin VB gene (MYO5B).

157 fatal cystic lung disease due to bi-allelic inactivating mutations in tuberous sclerosis complex (TS

158 utations in growth-controlling oncogenes and inactivating mutations in tumor-suppressor genes.

159 toxicity caused by ART and individuals with inactivating mutations may be predisposed to these effec

160 Somatic inactivating mutations of ARID1A, a SWI/SNF chromatin re

161 candidate cancer-associated genes, including inactivating mutations of the metalloproteinase ADAMTS12

162 Catalytic-inactivating mutations within the Drosophila enhancer H3

163 ity of human lung cancer cells bearing KMT2D-inactivating mutations.

164 n lead to the emergence and expansion of p53-inactivating mutations.

165 Here, we test this model in vivo by inactivating Myocardin, which prevented airway smooth mu

166 Inactivated myosin motors are folded against the filamen

167 -dendrites/somatic compartment included fast-inactivating Na(+) and delayed-rectifier K(+) conductanc

168 nnate immune cells, and subsequently phospho-inactivates Nedd4-2, an ubiquitin E3 ligase.

169 Mutations that inactivate negative translation regulators cause autism

170 anscription to fuel lipid peroxidation while inactivating Nrf2-mediated antioxidant defense and impai

171 Yet one can inactivate OFC without affecting well-practiced choices.

172 irs across a set of standard offers and then inactivating OFC subregions during choices between novel

173 the channels, it has more preference for the inactivated one.

174 in record time, allowing the development of inactivated or attenuated viral vaccines along with subu

175 pathological processes that were activated, inactivated, or unchanged vs. RVD with no intervention.

176 d Lys129 is removed by SIRT1, which promptly inactivates OTUD3 and thus allows timely induction of in

177 en used to eliminate wild microorganisms and inactivate oxidative enzymes.

178 itate dissociation of p53 from promoters and inactivate p53-mediated transcription.

179 links the major pathways by which mutations inactivate p53.

180 e in this system, here, we pharmacologically inactivated parts of vlPFC and simultaneously measured I

181 s of KcsA and MthK with strikingly different inactivating phenotypes.

182 broad phosphorylation changes, including an inactivating phosphorylation of beta-catenin and two mic

183 opsis thaliana), high temperature reversibly inactivates PHYB, reducing photomorphogenesis-dependent

184 embrane microdomains (aMMDs), which trap and inactivate physiological receptors, such as that for IL-

185 To this end, we inactivated PI3K by genetic means in the fly fat body an

186 ity in competition studies using homologous (inactivated Pitman Moore rabies virus) and heterologous

187 ing to "ene" hydroperoxides that in the dark inactivate planktonic Escherichia coli (E. coli).

188 l coverage through routine immunization with inactivated polio vaccine (IPV), to ensure type 2 immuni

189 booster dose of tetanus-diphtheria-pertussis inactivated polio vaccine (Tdap) 3 months later; BCG and

190 vaccinate children-who had only received the inactivated polio vaccine-with the oral polio vaccine (O

191 phtheria-tetanus toxoids-acellular pertussis-inactivated poliomyelitis-Haemophilus influenza type b-h

192 Intradermal (id) fractional inactivated poliovirus vaccine ([fIPV] one fifth of norm

193 Moreover, this technique was efficient for inactivating polyphenoloxidase.

194 causes defects in apical structures, even if inactivated post-mitotically.

195 strate that androgen exposure suppresses the inactivating post-translational modification phospho-Ser

196 Heat-inactivated PPE was used to generate a sham operative co

197 This study assessed inactivated prepandemic vaccine strains in a One Health

198 tosomal epivariations, including potentially inactivating promoter methylation events at 384 genes li

199 ral formulations with significant SARS-CoV-2 inactivating properties in vitro support the idea that o

200 that additional distraction reactions, where inactivated proteases become competitive inhibitors to r

201 Genetic variants that inactivate protein-coding genes are a powerful source of

202 human genetic variants that are predicted to inactivate protein-coding genes provide an in vivo model

203 ate-induced protein 60 (JIP60) is a ribosome-inactivating protein (RIP) from barley (Hordeum vulgare)

204 havior, as witnessed by expression of the NO-inactivating protein Hmp on the extreme periphery of mic

205 d MAPK/ERK pathways and dephosphorylates and inactivates pyruvate dehydrogenase kinase 1, Akt, Raf, m

206 a system of genetic switches to activate and inactivate reporter genes in a predetermined order.

207 Vaccination with formalin-inactivated "rewired" viruses significantly enhances the

208 Two effectors, YopE and YopT, inactivate RhoA to disrupt phagocytic signaling.

209 We found that inactivating rhodopsin signaling protected photoreceptor

210 However, what inactivates RyR2 and how RyR2 inactivation leads to Ca(2

211 Analyzing heat-inactivated samples with a luciferase immunoprecipitatio

212 the first evidence that sunlight may rapidly inactivate SARS-CoV-2 on surfaces, suggesting that persi

213 ma in order for ACE-2 to capture and thereby inactivate SARS-CoV-2.

214 he present study, simulated sunlight rapidly inactivated SARS-CoV-2 suspended in either simulated sal

215 evaluated using mock test samples containing inactivated SARS-CoV-2 virions, added to in vitro derive

216 adjustment for age and prior LAIV (n = 436), inactivated seasonal vaccine (n = 100), or (H1N1)pdm09 v

217 We found that inactivating SOM(+) cells, but not PV+ cells, significan

218 To discover inhibitors that are effective in inactivating sortases in vivo, we developed and implemen

219 B machinery and (b) a protease to cleave and inactivate specific substrates, including negative regul

220 Strategies to inactivate STAT3 are being pursued as potential anticanc

221 Surprisingly, although inactivating Stat3 in Pkd1-deficient tubules slightly re

222 3-3 adaptor proteins that hold CaMKK2 in the inactivated state by preventing dephosphorylation of pho

223 Transition to the inactivated state involves a secondary structure change

224 7 inhibitors that preferentially inhibit the inactivated state of the channel, ST-2262 is equipotent

225 which also bind with higher affinity to the inactivated state than the resting state but bind at a s

226 e of the channel, a protocol that favors the inactivated state, and a high frequency protocol.

227 d the output is the occupancy of a long-term inactivated state.

228 states (with D4S4 in the inner position) and inactivated states (with D4S4 in the outer position).

229 associated mutations dysregulate rather than inactivate SWI/SNF remodelers, our insights into RSC com

230 produced in trans by a gene drive either to inactivate the cas9 transgene (e-CHACRs) or to delete an

231 Without ACE2 acting as a guardian to inactivate the ligands of B1R, the lung environment is p

232 ong-standing paradigm for G1/S control, Cdks inactivate the retinoblastoma tumor suppressor protein (

233 apidly deploy anti-CRISPR proteins (Acrs) to inactivate the RNA-guided nucleases that enforce CRISPR-

234 quinoa seeds before consumption in order to inactivate the toxin, particularly in sprouts, generally

235 ent need for devices that can be deployed to inactivate the virus on both recently and existing conta

236 SUMOylation of PTEN and then correspondingly inactivated the AKT/mTOR signaling pathway.

237 act of sensory evidence, we chemogenetically inactivated the excitatory projections from auditory cor

238 emia cells increased ceramide levels 2-fold, inactivated the key signaling protein extracellular sign

239 We selectively inactivated the Mmp14 gene in Mphis using a genetic stra

240 We inactivated the Sry (sex-determining region Y)-box 2 (So

241 Using CRISPR, we inactivated the TET1 gene in H9 human embryonic stem cel

242 rmaldehyde incubation of infected cells also inactivated the virus.

243 asmid-encoded signalling peptide, Phr*pLS20, inactivates the anti-repressor of RcopLS20, named RappLS

244 delayed negative feedback loop in which Plk4 inactivates the interaction with its centriolar receptor

245 hereas the phosphomimetic Ser162Asp mutation inactivates the pump.

246 the antitoxin and the way that the antitoxin inactivates the toxin.

247 nin induces dephosphorylation of CpxA, which inactivates the transcriptional factor CpxR controlling

248 coding an anti-CRISPR protein (AcrVIA1) that inactivates the type VI-A CRISPR system of Listeria seel

249 In the nucleus, caspase-8 cleaves and inactivates the ubiquitin-specific peptidase 28 (USP28),

250 prevents premature chromosome segregation by inactivating the anaphase promoting complex/cyclosome (A

251 ying the e-CHACR and the second mutating and inactivating the cas9 transgene.

252 r cells may adapt to high levels of Akt3, by inactivating the DNA damage response.

253 inking the Ube2N and Ub subunits effectively inactivating the E2~Ub conjugate.

254 ates with Ras(V12) to drive tumor growth via inactivating the Hippo pathway.

255 human gut bacterial isolates were capable of inactivating the identified azo dye excipients, producin

256 ity of Bad is cryptic and can be unmasked by inactivating the intrinsic nuclease activity.

257 Thus, we found that co-inactivating the Myt TFs in mouse pancreatic progenitors

258 Also, inactivating the small RNA RybB which represses rluD led

259 directly investigated the role of inputs by inactivating the thalamus; this perturbed cortical activ

260 cacy of mild fever over a period of ~24 h in inactivating the virus.

261 ation of GRK1 activity and its efficiency in inactivating the visual pigment.

262 ancer progression: most carcinoma cells have inactivated their epithelial antiproliferative response

263 epletion of cholesterol from HIV-1 particles inactivates their infectivity.

264 to limit airborne viral transmissions is to inactivate them within a short time of their production.

265 AANAT1 acetylates monoamines and inactivates them, and we found that AANAT1 limited the a

266 bioassays, we found that the helper bacteria inactivate tolaasin by linearizing the lipocyclopeptide.

267 aning effect of ELT is due to the ability to inactivate toxic and chromophore functional groups, tran

268 We find that inactivating TRIM37 improves acentrosomal mitosis becaus

269 FBXW7 targeted the frequently inactivated tumor suppressor KMT2D for protein degradati

270 e transcriptional repressor role of SerRS is inactivated under hypoxia through phosphorylation by ata

271 ll number of bacterial genes are known to be inactivated upon IGE integration and reactivated upon ex

272 ain (H1/stalk) following trivalent influenza inactivated vaccine (IIV3) immunization in pregnant wome

273 accine (n = 20), live-attenuated followed by inactivated vaccine (n = 15), twice AS03-adjuvanted inac

274 ated vaccine (n = 15), twice AS03-adjuvanted inactivated vaccine (n = 16) or placebo (n = 5, intranas

275 live-attenuated followed by AS03-adjuvanted inactivated vaccine (n = 20), live-attenuated followed b

276 a single-dose immunization of ZIKV purified inactivated vaccine (ZPIV)(4-7) in a dengue virus (DENV)

277 his vaccine response, we immunized mice with inactivated vaccine and injected Ag-pulsed activated APC

278 Our results using inactivated vaccine candidates from the human pandemic p

279 This suggests that CD4 effectors induced by inactivated vaccine require high levels of cognate Ag re

280 sus nonadjuvanted H5N1 avian influenza virus inactivated vaccine.

281 se (HD) and the standard-dose (SD) trivalent inactivated vaccine.

282 gs strongly support the causal role of GFRA1-inactivating variants for an autosomal recessive, nonsyn

283 isorder but the most frequently results from inactivating variants in genes encoding subunits of succ

284 Here we report that bi-allelic inactivating variants in SCUBE3 have pleiotropic consequ

285 TSC results from inactivating variants within the TSC1 or TSC2 genes, lea

286 phenotype similar to TNBC tumors with BRCA1-inactivating variants, and it can be observed in matched

287 ty, and interchangeability of a single-dose, inactivated, Vero-cell derived, JENVAC to the live-atten

288 Pitman Moore rabies virus) and heterologous (inactivated vesicular stomatitis virus) antigens and acc

289 the efficacy of our HUDSON protocol in heat-inactivating VHF viruses before SHERLOCK testing, elimin

290 sponsive enhancer that becomes progressively inactivated via Polycomb-mediated silencing as discs mat

291 A rapid inactivation protocol capable of inactivating virions, as well as endogenous nucleases, w

292 ies, we have tested methods commonly used to inactivate virus and prepare the sample for additional e

293 e culture infective dose (TCID(50))/ml using inactivated virus and 25 copies/ml (c/ml) using syntheti

294 Vaccination with inactivated virus vaccines has been applied for several

295 wed similar limits of detection (LODs) using inactivated virus, with 100% detection, ranging from 500

296 We improve HUDSON to rapidly inactivate viruses in nasopharyngeal swabs and saliva in

297 Animals with procaine-inactivated VLs had tortuous paths and were unable to fi

298 compared live infection with influenza to an inactivated whole influenza vaccine.

299 f prehypertrophic chondrocyte-like cells and inactivates Wnt signaling, but its interactive role with

300 of an aluminum hydroxide adjuvanted purified inactivated Zika vaccine (PIZV) against challenge with Z