ライフサイエンスコーパス: inappropriate

1 aching transgressors that their behaviour is inappropriate).

2 Of these, 1,120 (54.4%) urine cultures were inappropriate.

3 of all urine cultures repeated in <48 h were inappropriate.

4 om the landing motor pathway when landing is inappropriate.

5 riate and 2 results (18% [CI, 3% to 52%]) as inappropriate.

6 he proportion of such prescriptions that are inappropriate.

7 ion used in many published papers is clearly inappropriate.

8 d, has been unsuccessful, or has been deemed inappropriate.

9 A median value of 1.0 to 3.4 was considered inappropriate, a median value of 3.5 to 6.9 was consider

10 pproach leads to the potential premature and inappropriate abandonment of radiotherapy in combination

11 ppropriate; prophylactic regimens were often inappropriate across different ICU types, particularly i

12 IL facilitates active avoidance but suppress inappropriate actions in appetitive and aversive context

13 RAF activity is tightly regulated and inappropriate activation is a frequent cause of cancer(4

14 d MRGPRX2 expression on mast cells and their inappropriate activation may contribute to periodontitis

15 tects t-loops from promiscuous unwinding and inappropriate activation of ATM, but also counteracts re

16 loit Spy1 to stimulate proliferation through inappropriate activation of Cdks, yet the mechanism is u

17 ting from a dysregulated immune response and inappropriate activation of coagulation.

18 Inappropriate activation of endosomal TLR7 and TLR8 occu

19 Lung cancers are frequently characterized by inappropriate activation of epidermal growth factor rece

20 In addition, by preventing inappropriate activation of excitatory memory engrams, i

21 ive regulation of myosin activity to prevent inappropriate activation of filopodia formation.

22 Inappropriate activation of the cystic fibrosis transmem

23 n requires glp-1/Notch and is accompanied by inappropriate activation of the GLP-1 target sygl-1 in P

24 s nucleic acids are essential for preventing inappropriate activation of the innate antiviral respons

25 mutations in the translational machinery or inappropriate activation of the integrated stress respon

26 Inappropriate activation of the p53 transcription factor

27 Inappropriate activation of the renin-angiotensin system

28 Inappropriate activation of the stroma potentiates the g

29 s differences in the diseases resulting from inappropriate activation of TLR9 and TLR7.

30 The inappropriate activation of transcription factors, inclu

31 e/IL-12/NK cell/IFN-gamma axis that prevents inappropriate allergic type 2 immune responses on respir

32 origins in ineffective experimental designs, inappropriate analyses and/or flawed reasoning.

33 nts); of these, 112 (31%) were identified as inappropriate and administered greater than 72 hours amo

34 n uptake above that of the liver seems to be inappropriate and associated with potential harm for DLB

35 fruits and vegetables), the colorimeters are inappropriate and inaccurate.

36 ys on the basis of histologic factors may be inappropriate and merits further study.

37 bacteria, a problem possibly exacerbated by inappropriate and non-optimal application.

38 Inappropriate and pathological aggression plays a leadin

39 e is opportunity for further improvement, as inappropriate and suboptimal prescribing remained common

40 Medicare Act of 2014 (PAMA), aims to reduce inappropriate and unnecessary imaging by mandating use o

41 sceptibility of bacteria is vital to prevent inappropriate and untargeted use of antibiotics and cont

42 nal tests based on unconstrained data become inappropriate, and new statistical methods are needed to

43 Emerging pandemic infectious threats, inappropriate antibacterial use contributing to multidru

44 Inappropriate antibiotic prescribing can contribute to m

45 Inappropriate antibiotic prescribing causes widespread s

46 Inappropriate antibiotic prescribing contributes to the

47 One underexplored driver of inappropriate antibiotic prescribing for acute respirato

48 unters are increasing and have high rates of inappropriate antibiotic prescribing.

49 e treatment efficacy while limiting costs of inappropriate antibiotic prescription.

50 Of patients on inappropriate antibiotic therapy in surgical ICUs, a sta

51 to ensure accurate UTI diagnosis and reduce inappropriate antibiotic treatment.

52 ain reaction (PCR) results could help reduce inappropriate antibiotic use in patients with likely vir

53 Opportunities to further mitigate inappropriate antibiotic use may be realized by combinin

54 it (ICU) setting can reduce harms related to inappropriate antibiotic use.

55 ic decision-making, leading to prolonged and inappropriate antibiotic use.

56 ing alternative to empiric therapy, reducing inappropriate antibiotic use.

57 Inappropriate antibiotics, previous antibiotic exposure,

58 Inappropriate antibiotics, previous antibiotic exposure,

59 c perturbations in these checkpoints lead to inappropriate antibody responses, which might have impor

60 the hyponatremia induced by the syndrome of inappropriate antidiuresis (SIAD) are inadequate.

61 serious adverse events occurred: one case of inappropriate antidiuretic hormone secretion and one of

62 Discontinuation of inappropriate antimicrobial therapy is an important targ

63 en recognized as an important contributor to inappropriate antimicrobial use, which promotes emergenc

64 eeded to assess contextually appropriate and inappropriate anxiety.

65 Cocoa smoky off-flavour is generated from an inappropriate artificial drying applied on beans to spee

66 Fluoroquinolones were more likely to be inappropriate at hospitals without a strategy (52.8%) ve

67 Fluoroquinolones were more likely to be inappropriate at hospitals without a strategy (52.8%) ve

68 Manning builds an inappropriate Bayesian age model to assert that the init

69 Secondary outcomes included proportion of inappropriate BCx, solitary BCx, and positive BCx.

70 The proportion of inappropriate BCxs did not significantly change with the

71 Also, inappropriate behavioral choices were evoked by the mist

72 present a model whereby centrosomes prevent inappropriate beta-catenin modifications that antagonize

73 ics prescribed for hospitalized patients are inappropriate, but pediatric data are limited.

74 viduals diagnosed with CKD could help reduce inappropriate care and its associated adverse effects.

75 uard against wasteful oxygen consumption and inappropriate cell growth during hypoxia.

76 luation of rewards or the failure to inhibit inappropriate choices.

77 all research topics, potentially leading to inappropriate conclusions about the overall strength of

78 er to distinguish if an excessive milling or inappropriate configurations of ultracentrifugal mill ar

79 Therefore, Pten loss results in inappropriate connectivity whereby neurons are coupled t

80 Together with the inappropriate consideration of risk factors revealed by

81 The same definition of R0 is likely inappropriate considering the anatomy and etiology of lo

82 We separated appropriate from inappropriate contacts to FTC transmissions in the OptiL

83 ction, delirium severity (insufficient SOE), inappropriate continuation, and sedation (insufficient S

84 whether international regulations governing inappropriate CRISPR utilization should be crafted and p

85 or intervention in diseases characterized by inappropriate Cu accumulation.

86 onent of the protective immune response, but inappropriate cytokine expression can exacerbate TB.

87 results suggest that artifacts arising from inappropriate data evaluation might contribute to the va

88 to difficulty gathering and synthesizing or inappropriate data filtering, can lead clinicians to mis

89 tery bypass graft surgery that were rated as inappropriate decreased from 2,956 patients in 2010 to 9

90 sues may have mechanisms to sense and resist inappropriate dedifferentiation.

91 Removal of Tbx5 in vivo precipitated inappropriate depolarizations in the atrioventricular (H

92 tress response that is probably secondary to inappropriate derepression of cholesterol biosynthesis.

93 d certain forms of asthma resulting from the inappropriate development of immune responses to otherwi

94 mplex is likely to be involved in inhibiting inappropriate differentiation, as it localized to a numb

95 Inappropriate disclosure of human genomes may put the pr

96 However, inappropriate discontinuation or narrowing of antibiotic

97 cessing of DNA underlies all DNA repair, yet inappropriate DNA processing must be avoided.

98 EX1 enzymatic activity is crucial to prevent inappropriate DNA sensing and IFN-I production in immune

99 PPE effectiveness is often undermined by inappropriate doffing methods.

100 cessful discontinuation of use of at least 1 inappropriate drug (that is, without relapse or severe w

101 a prescription may increase unnecessary and inappropriate drug use or doses as well as global risk f

102 Prescriptions were of inappropriate duration in 20% of oral prescriptions (ran

103 ); (4) the proportion of oral antibiotics of inappropriate duration; and (5) the proportion of antibi

104 es facing problems with after-hours care and inappropriate emergency department visits.

105 ixed infections are more likely to result in inappropriate empiric antibiotic therapy.

106 We aimed to describe the current rates of inappropriate empirical antibiotic treatment (IEAT) in o

107 Management variables, such as inappropriate empirical antibiotic treatment or days to

108 n unperturbed cells, NUCKS1 prevents RAD54's inappropriate engagement with RAD51AP1.

109 Thus, our results suggest that inappropriate engram reactivation underlies cognitive de

110 ancer functions, but unexpectedly results in inappropriate enhancer activation during stages when hor

111 discharge fluoroquinolone prescriptions were inappropriate, especially in hospitals without a strateg

112 discharge fluoroquinolone prescriptions were inappropriate, especially in hospitals without a strateg

113 fectiveness of two policies or treatments as inappropriate even when universally implementing either

114 Inappropriate expression of MMP9 also contributes to imp

115 rs by Lsr2 may protect Streptomyces from the inappropriate expression of specialized metabolites, and

116 operates in conjunction with KLF4 to repress inappropriate expression of Tgm1, Krt16, and Aqp3 In par

117 sorder, PFC hyperactivity is associated with inappropriate fear in safe situations.

118 ch offer drug-consumption opportunities, are inappropriate for addicted individuals seeking treatment

119 elective emitter materials are inadequate or inappropriate for building applications, here we present

120 As the term photorespiration is inappropriate for describing phosphoglycolate recycling

121 ntional colorimetric ELISA, which in turn is inappropriate for determination of diclofenac in seawate

122 irmation of MMP by autoantibody detection is inappropriate for DIF- ocular-only MMP patients, resulti

123 often results in poor quality RNA, making it inappropriate for downstream applications.

124 Brette argues that coding as a concept is inappropriate for explanations of neurocognitive phenome

125 heir toxic and nonreusable nature makes them inappropriate for large-scale production.

126 the traditional 2-h postingestion BHI may be inappropriate for older adults.

127 Unfortunately, most tools are inappropriate for that while our language takes mediatio

128 al reads per million normalization method is inappropriate for the evaluation of ChIP-seq data when t

129 stry is often unavailable, unaffordable, and inappropriate for the majority of these populations, but

130 over shorter distances but was thought to be inappropriate for the treatment of solid tumors, for whi

131 Soft particle theory was deemed inappropriate for this system.

132 Loss of Smad4 causes the formation of inappropriate, fragile connections between arteries and

133 Inappropriate gating can lead to pathologies.

134 development to prevent genomic instability, inappropriate gene activation and other maladaptive proc

135 opmentally poised genes poorly while lineage-inappropriate genes, including extra-embryonic genes, ar

136 ro slope is exaggerated by measurement of an inappropriate geometrical quantity (e.g., length instead

137 ner classes that prevents their targeting to inappropriate glomeruli in the antennal lobe.

138 ed task performance, primarily by increasing inappropriate Go responses.

139 ene loci examined with certain genes showing inappropriate HDAC2 repressor enrichment.

140 Thus, inappropriate HIF-1alpha signalling results in skeletal

141 Confirmatory testing prevents inappropriate HIV diagnosis, is cost-saving, and should

142 Inappropriate ICD shocks in 39 patients occurred most co

143 iagnostic work-up of multiple sclerosis, but inappropriate image interpretation and application of MR

144 ally in a healthy host, posing the threat of inappropriate immune activation.

145 an autoimmune condition characterized by an inappropriate immune reaction against gluten.

146 n release nucleic acids that might induce an inappropriate immune response.

147 of self-derived nucleic acids that drive an inappropriate immune response.

148 hma is a chronic lung disease resulting from inappropriate immune responses to environmental antigens

149 Inappropriate immunoglobulin A targeting of Clostridia a

150 ection or infectious events being results of inappropriate immunosuppression.

151 because of device-related complications and inappropriate implantable cardioverter defibrillator int

152 were appropriate in 65.0% of prescriptions, inappropriate in 12.5% (range across EDs: 0.6%-29.3%), a

153 Post-discharge fluoroquinolones were deemed inappropriate in 154 of 375 (41.1%) patients.

154 Postdischarge fluoroquinolones were deemed inappropriate in 154 of 375 (41.1%) patients.

155 However, their limitations make them inappropriate in some cases.

156 for those without coexistent RPD and may be inappropriate in those with RPD, warranting caution when

157 appropriate indication (presumed bacterial), inappropriate indication (presumed viral), or inconclusi

158 y these assumptions and therefore may reduce inappropriate inferences.

159 perfluous neutrophil recruitment, leading to inappropriate inflammation and injury.

160 Psychological stressors and inappropriate inflammation increase the risk and severit

161 ease NETs to exacerbate tissue damage during inappropriate inflammation.

162 patients, consistently revealed a unique and inappropriate inflammatory response.

163 sses, new approaches for quieting chronic or inappropriate inflammatory states may be revealed and th

164 ntial to avoid emergence of complications or inappropriate interventions.

165 s in the functions of the organelles lead to inappropriate intracellular activation of trypsinogen an

166 Here we show that inappropriate, learning-resistant fear behavior results

167 STN-projecting neurons reduced and increased inappropriate licking, respectively, partly through thei

168 sregulation in early programming events with inappropriate lineage-specific signatures apparent with

169 ing to promote cell survival in the event of inappropriate living conditions such as nutrient shortag

170 luding failure to establish homolog pairing, inappropriate loading of SC subunits onto unpaired chrom

171 r which the therapy in this trial was deemed inappropriate), malignant peripheral nerve sheath tumour

172 and overtreatment are often used to describe inappropriate management of older adults with cancer.

173 Misclassifications could result in inappropriate management of paediatric respiratory illne

174 ores in all cases does not necessarily imply inappropriate management, and the performance of global

175 hough physicians are not required to provide inappropriate medical therapies.

176 The 3MR is effective in discontinuing inappropriate medication use in frail nursing home resid

177 h antidementia drugs, and use of potentially inappropriate medication.

178 Choosing an inappropriate method weakens statistical power and intro

179 Application of inappropriate methods may lead to incorrect and inconsis

180 findings indicate no evidence of widespread inappropriate methods to improve performance on D2B time

181 data suggest that 30-day mortality may be an inappropriate metric to assess procedural quality.

182 s therapeutic opportunities for disorders of inappropriate mineralization.

183 Inappropriate mitosis-like chromosome segregation in mei

184 to prevent irrelevant activity from inducing inappropriate modifications.

185 opose that during motoric response-conflict, inappropriate motor activity is actively (and perhaps no

186 y rapidly and non-selectively net-inhibiting inappropriate motor tendencies.

187 In this study, we found inappropriate mTOR localization at the lysosome under nu

188 iseases that are characterized by altered or inappropriate neural function and behaviour.

189 be maintained throughout beta-selection, but inappropriate Notch activation in DN4 and DP cells is on

190 Given the importance of inappropriate NOTCH1 signalling in T-cell acute lymphobl

191 xual behaviour in dementia as appropriate or inappropriate often applied in institutional settings, f

192 ck events were adjudicated and classified as inappropriate or appropriate, and HCU and expenditures,

193 are curative, and disputes about potentially inappropriate or futile treatment.

194 Overall, one-third of prescriptions were inappropriate or inconclusive, with marked variation bet

195 at were classified as suboptimal, defined as inappropriate or needing modification.

196 to transition-state stabilization suppresses inappropriate or premature cleavage, enhancing processin

197 sis patients suppresses T cells by promoting inappropriate P2Y11 receptor stimulation that impairs T

198 We demonstrate that inappropriate p53 activation in the neural crest, facial

199 Gini coefficient may be unstable and select inappropriate parameters, especially in complex practica

200 hat HPV E6 and E7 allow HR to initiate at an inappropriate part of the cell cycle.

201 changes over time in the number and rate of inappropriate PCIs.

202 trypsin digestion-based methods due to their inappropriate peptide length for MS analysis, indicating

203 pairwise SC assembly in hal mutants reflects inappropriate PLK activity.

204 troversies have expressed concerns about the inappropriate politicization of science.

205 common mRNA defect in eukaryotes is probably inappropriate polyadenylation at near-cognate sites with

206 Cocoa smoky off-flavor is due to inappropriate post-harvest processing and cannot be remo

207 However, the mechanism preventing inappropriate post-synaptic glutamatergic effects is une

208 ing repeated cortical activation may promote inappropriate prepotent responses in LLD.

209 Characterization of inappropriate prescribing practices for children is need

210 report of prescribers being disenrolled for inappropriate prescribing.

211 hlighting a need for initiatives to decrease inappropriate prescribing.

212 assessed rationality, and the proportion of inappropriate prescription among patients with various c

213 ronic CSC with RPE tear is critical to avoid inappropriate procedures and to prevent severe visual lo

214 e study, 31% of ICU antibiotic regimens were inappropriate; prophylactic regimens were often inapprop

215 ssings (FTC) were low indicating physicians' inappropriate reactions to alerts.

216 stent cohesion protects short telomeres from inappropriate recombination.

217 nd biomes have repeatedly been recognized as inappropriate regions for expanding tree cover due to th

218 tic consequences often culminate to generate inappropriate regulation of neuronal circuit activity.

219 nosing OA when it is not present may lead to inappropriate removal from exposure and unnecessary fina

220 CI, 0.53 to 0.80) was less likely to have an inappropriate repeat culture.

221 We defined an inappropriate repeat urine culture to be a repeat urine

222 Predictors for inappropriate repeat urine cultures included collection

223 We analyzed the proportion of inappropriate repeat urine cultures performed <48 h afte

224 The estimated laboratory charges for inappropriate repeat urine cultures were $16,800 over th

225 , diagnostic yield, and cost associated with inappropriate repeat urine cultures.

226 amme value, including costs and avoidance of inappropriate resource utilisation; and ability of progr

227 how that glial cells at the NMJ elaborate an inappropriate response to NMJ degeneration in a manner t

228 an important host defense mechanism to avoid inappropriate responses that may exacerbate mucosal inju

229 e that restrain mature B cells from mounting inappropriate responses to endogenous antigens, and plac

230 fertilization represents a scenario wherein inappropriate responses to exogenous yet non-pathogen-de

231 lyses show that abscission failure is due to inappropriate retention of F-actin at the intercellular

232 actomyosin contractility, which results from inappropriate RhoA activation.

233 e EchoWISELY randomized clinical trial (Will Inappropriate Scenarios for Echocardiography Lessen Sign

234 Both aging and inappropriate secretion of aldosterone increase the risk

235 hway can be potentially exploited to prevent inappropriate secretion of IFN-I in autoimmune diseases

236 ctions and noxious agents while avoiding the inappropriate sensing of self-DNA.

237 The inappropriate shock rate (3.1% at 1 year) is the lowest

238 of the S-ICD by evaluating complications and inappropriate shock rate.

239 t ventricular dysfunction, and received more inappropriate shocks (IAS) than in typical transvenous I

240 Nine patients (8.7%) experienced 37 inappropriate shocks (incidence rate 0.9 per 100 person-

241 Frequency of inappropriate shocks decreased over follow-up, likely re

242 with at least 1 ICD complication, including inappropriate shocks in 42 (25.5%) patients and lead dys

243 (hazard ratio, 0.69; 95% CI, 0.44 to 1.09); inappropriate shocks occurred in 41 and 29 patients, res

244 Expenditures related to appropriate and inappropriate shocks were not significantly different.

245 cular procedures was substantial, even after inappropriate shocks, which comprised 38% of all shocks.

246 respect to device-related complications and inappropriate shocks.

247 omposite of device-related complications and inappropriate shocks; the noninferiority margin for the

248 nt for clearing extracellular pathogens, but inappropriate signaling has been linked to acute respira

249 Yet, in inappropriate sinus tachycardia (IST), postural tachycar

250 Cardiac arrhythmias (i.e. inappropriate sinus tachycardia and bradycardia, asystol

251 nd side sleeping, soft bedding, bed sharing, inappropriate sleep surfaces (including sofas), exposure

252 increased aberrant behaviors associated with inappropriate, stereotypic speech.

253 Inappropriate stimulation or defective negative regulati

254 Variability in electrode placement and inappropriate stimulation settings may account for a lar

255 action, preventing ectopic functionality at inappropriate subcellular loci and orienting tissue morp

256 a clinical challenge and is needed to avoid inappropriate surgery.

257 odevelopmental disorder characterized by age-inappropriate symptoms of inattention, impulsivity, and

258 anisms that could underlie the repression of inappropriate synapse formation, and suggest mechanistic

259 ion after SCI is dysregulated in part due to inappropriate synthesis of proresolving lipid mediators.

260 As inappropriate T cell activation can cause disease, T cel

261 ganisms, while suppressing the activation of inappropriate T cell responses to resident microorganism

262 entiation through enhancer reprogramming via inappropriate targeting of SMARCA4.

263 preventing premature interaction with stage-inappropriate targets.

264 products, such as food and drugs exposed to inappropriate temperature, cause million illnesses every

265 ism may play an important role in preventing inappropriate Th cell responses under normal conditions.

266 , it may raise diagnostic issues, leading to inappropriate therapeutic procedures.

267 was associated with lower mortality than was inappropriate therapy (132 [38.5%] of 343 patients died

268 r implementation, but did show a decrease in inappropriate therapy (45% vs 31%, P < .05).

269 24% compared with 47% in those who received inappropriate therapy (P = .016), despite switching to a

270 atic Defibrillator Implantation Trial-Reduce Inappropriate Therapy).

271 rted in the first 5 days after infection) or inappropriate therapy, and for patients receiving approp

272 or noninfectious or nonbacterial reasons for inappropriate therapy.

273 ctors is regulated to prevent DNA binding at inappropriate times.

274 ased analyses indicated substantial rates of inappropriate TIRF use.

275 es and leads to numerous eQTL assignments in inappropriate tissues among these 18 genes.

276 to another TKI or if they are switched to a inappropriate TKI or TKI dose.

277 Overall, this study demonstrates that inappropriate TLR9 responses can drive a severe autoinfl

278 ntific, ethical, and policy questions, it is inappropriate to perform germline gene editing that culm

279 s of the general public perceive fears about inappropriate touching, accusations of sexual assault, a

280 We conclude that CHD4 inhibits inappropriate transcription in pro-B cells.

281 rs addressed family requests for potentially inappropriate treatment (9/20, 45%) or medical decision-

282 -R-BSI) leads to a trade-off between empiric inappropriate treatment (IAT) and unnecessary carbapenem

283 d risk of subsequently receiving potentially inappropriate treatment in Veterans Health Administratio

284 This inappropriate treatment primarily impacts patients with

285 significant risk ratio of 1.76 and 1.90 for inappropriate treatment, respectively.

286 from low-income countries frequently receive inappropriate treatment.

287 Although inappropriate tumoral secretion of calcitriol is typical

288 urinary tract infection is often preceded by inappropriate urine culturing.

289 ersonnel identified most salient reasons for inappropriate use by category and agent.

290 Reasons for inappropriate use included unnecessarily broad spectrum

291 e supporting the desired outcome of reducing inappropriate use of advanced imaging is lacking.

292 fective clinical management and to the limit inappropriate use of antibiotics.

293 tionable data, implementation obstacles, and inappropriate use of PROMs as a performance metric, with

294 failure to appreciate disease heterogeneity, inappropriate use of rodent models of disease, inadequac

295 In this review, we illustrate how inappropriate use of the MM rate law distorts the dynami

296 Most common reasons for inappropriate use were bug-drug mismatch (27.7%), surgic

297 set of studies reported a high proportion of inappropriate use, the true extent could not be assessed

298 om usual practice manifested as occasionally inappropriate utilization of skills, management of posto

299 Complications from inappropriate warfarin dosing are one of the most common

300 r outcome is inevitable but also to avoid an inappropriate withdrawal of life-sustaining treatment in