ライフサイエンスコーパス: inbreeding depression

1 nd elsewhere, and there was some evidence of inbreeding depression.

2 reproductive success, a phenomenon known as inbreeding depression.

3 y observed association between herkogamy and inbreeding depression.

4 endosperm imprinting, hybrid phenotypes and inbreeding depression.

5 ly recessive deleterious alleles will reduce inbreeding depression.

6 The advantage is inversely related to local inbreeding depression.

7 es with long generation intervals and severe inbreeding depression.

8 tilization selection, and/or the severity of inbreeding depression.

9 ul tool to study the genetic architecture of inbreeding depression.

10 lations have rendered the species at risk of inbreeding depression.

11 srupting self-incompatibility and leading to inbreeding depression.

12 ns and may contribute substantially to total inbreeding depression.

13 d not appreciably diminish overall levels of inbreeding depression.

14 igh levels of selfing in plants despite high inbreeding depression.

15 of floral size expressed highly significant inbreeding depression.

16 system itself in response to such factors as inbreeding depression.

17 he relationship between prior inbreeding and inbreeding depression.

18 o identify genomic correlates of fitness and inbreeding depression.

19 he evolutionary consequences of sex-specific inbreeding depression.

20 negatively impact population growth through inbreeding depression.

21 ht on the genetic mechanisms contributing to inbreeding depression.

22 eding coefficient was correlated with higher inbreeding depression.

23 adaptive benefits to dingoes and alleviated inbreeding depression.

24 sex-specific differences in the magnitude of inbreeding depression.

25 will be impeded by genetic factors, such as inbreeding depression.

26 les may reduce fitness in a process known as inbreeding depression.

27 becoming small, isolated, and threatened by inbreeding depression.

28 deleterious variation, reducing the risk of inbreeding depression.

29 between long runs of homozygosity (ROH) and inbreeding depression.

30 ecause of elevated inbreeding and subsequent inbreeding depression.

31 on sizes may thus in the near future lead to inbreeding depression.

32 g inbreeding depression or selfing with weak inbreeding depression.

33 le of reversible epigenetic modifications in inbreeding depression.

34 aving many vulnerable to genomic erosion and inbreeding depression.

35 racteristics that can affect the severity of inbreeding depression.

36 while simultaneously estimating sex-specific inbreeding depression.

37 or inviable, sl-CSD can generate substantial inbreeding depression.

38 ficient, revealing direct, but not indirect, inbreeding depression.

39 fects on viability, are contributing to this inbreeding depression.

40 to strong genetic drift and at high risk of inbreeding depression.

41 vated levels of inbreeding can be reduced by inbreeding depression.

42 als dynamic genome evolution and hotspots of inbreeding depression.

43 aphroditic selfing rates and the strength of inbreeding depression.

44 ay express recessive genetic load and suffer inbreeding depression.

45 S-linked genetic load compared with overall inbreeding depression.

46 itland approach for field-based estimates of inbreeding depression.

47 s sizes, and to estimate the power to detect inbreeding depression.

48 which estimate of F is optimal for detecting inbreeding depression.

49 nservation and ecology, such as the study of inbreeding depression.

50 opulations may be subject to consequences of inbreeding depression.

51 alleles, supporting the dominance theory of inbreeding depression.

52 pulation numbers, and reverse indications of inbreeding depression.

53 n but may also rescue small populations from inbreeding depression [1-3].

54 ch, we highlight the need to further explore inbreeding depression across different species to determ

55 se data to determine the extent and cause of inbreeding depression across other plant genomes.

56 The extent to which inbreeding depression affects longevity and patterns of

57 rowing, populations, further suggesting that inbreeding depression affects population fitness.

58 mula: see text]) to quantify the strength of inbreeding depression: allele-sharing, two versions of t

59 may create a benign environment that offsets inbreeding depression, allowing inbred societies to evol

60 Moreover, inbreeding depression alone does not generally account f

61 native populations, which may indicate that inbreeding depression alone is insufficient to prevent t

62 e detected: (i) variation in reproduction or inbreeding depression among life stages, years and mater

63 We observed a significant inbreeding depression and an increase of genetic varianc

64 cognized as a crucial strategy to counteract inbreeding depression and boost genetic variation in sma

65 enecks deplete genetic diversity, exacerbate inbreeding depression and decrease population viability.

66 on the relationship between the magnitude of inbreeding depression and environmental stress and calcu

67 find strong support for interactions between inbreeding depression and environmental variation compar

68 pports the dominance theory of heterosis and inbreeding depression and establishes the oyster as an a

69 ed levels of inbreeding increase the risk of inbreeding depression and extinction, yet many inbred sp

70 depletions of ROH as potential hotspots for inbreeding depression and find multiple exons where ROH

71 Inbreeding depression and genetic load have been widely

72 We investigated inbreeding depression and genetic load in a small (N(e)

73 Inbreeding depression and genetic purging are important

74 lyses on detection and quantification of the inbreeding depression and genetic purging of biological

75 In fact, with strong inbreeding depression and high selfing rates, evolution

76 Here, we investigate sex determination, inbreeding depression and inbreeding avoidance in Neodip

77 Siring probability also showed inbreeding depression and increased with male age, while

78 come expressed in homozygotes, thus reducing inbreeding depression and increasing population viabilit

79 Processes including inbreeding depression and its impact on allelic and phen

80 Inbreeding depression and lack of genetic diversity in i

81 duction traits but there is an indication of inbreeding depression and loss of genetic diversity due

82 Here we show low inbreeding depression and marker-based estimates of self

83 etic selection for the joint distribution of inbreeding depression and mating system across species.

84 tential to influence the coevolution between inbreeding depression and mating system.

85 rare plants with mixed-mating systems, where inbreeding depression and pollinator scarcity may both c

86 f these evolutionary factors on the level of inbreeding depression and provides an approach that coul

87 of genetic diversity, potentially leading to inbreeding depression and reduced adaptability.(1) Durin

88 Rare species also could suffer from inbreeding depression and reduced fertilization efficien

89 tically established, despite being linked to inbreeding depression and sexual selection.

90 species may be particularly at risk because inbreeding depression and stochastic fluctuations in mal

91 The causes of inbreeding depression and the converse phenomenon of het

92 We propose that the lack of inbreeding depression and the strong subdivision that ch

93 anscription play a role in hybrid vigour and inbreeding depression, and also in the absence of parent

94 a detailed examination of genomic diversity, inbreeding depression, and extinction risk in a collapsi

95 scue in facilitating adaptation and reducing inbreeding depression, and suggest that demographic resc

96 luding the rate of adaptation, the extent of inbreeding depression, and the load of deleterious mutat

97 the 119 populations although the severity of inbreeding depression appears to vary among taxa.

98 Differential effects of inbreeding depression are also observed between study si

99 esting that genetic variants associated with inbreeding depression are predominantly rare.

100 that the deleterious effects of inbreeding (inbreeding depression) are expected to be more pronounce

101 The magnitude of inbreeding depression as expressed in the field can be e

102 f immigrants can face reduced fitness due to inbreeding depression as fewer new individuals arrive.

103 recessive alleles are the primary source of inbreeding depression, as does its late expression in bo

104 sity may contribute to an elevated impact of inbreeding depression, as evidenced by reduced survival

105 Inbreeding depression associated with CSD is therefore e

106 ergence at the range limit, suggesting local inbreeding depression at both range limit populations; h

107 ought to increase relative female fitness is inbreeding depression avoidance, the magnitude of which

108 Here, we estimated impacts of inbreeding depression (B, lethal equivalents) across lif

109 Multiplicative inbreeding depression (based on seed germination, early

110 terious alleles can lead to large amounts of inbreeding depression because of their high equilibrium

111 e survival of small populations by producing inbreeding depression, but also exposes recessive delete

112 We investigated evidence for inbreeding depression by environment interactions in nin

113 Genetic purging reduces inbreeding depression by removing these alleles when exp

114 reting the genetic basis of the variation in inbreeding depression by: (1) predicting the variation i

115 Genetic factors such as inbreeding depression can also affect population dynamic

116 depression." There is mounting evidence that inbreeding depression can be exacerbated by environmenta

117 family structure is present, the strength of inbreeding depression can be most efficiently estimated

118 antial fraction of their inbreeding load and inbreeding depression can be purged when breeding contri

119 The magnitude of inbreeding depression can influence many aspects of a po

120 These results demonstrate that inbreeding depression can substantially limit the recove

121 dicts that, at equilibrium, the magnitude of inbreeding depression caused by recessive alleles should

122 on among populations, suggesting that future inbreeding depression could potentially be mitigated by

123 such as variation in male mating ability and inbreeding depression could potentially lead to the long

124 ion in the odds of survival in lambs, though inbreeding depression decreases with age.

125 The selfer population experienced much lower inbreeding depression (delta = 0.05 +/- 0.02 SE) than th

126 ditions, there was a large sex difference in inbreeding depression (delta) and the inbreeding load (L

127 ad, 2) purging, and 3) the highest predicted inbreeding depression, despite purging, in the small-iso

128 Inbreeding depression did not increase at later ages for

129 The change in inbreeding depression due to purging averaged across the

130 In this way we introduce the concept of "inbreeding depression effect variance," a parameter more

131 rstanding how spatial structure can generate inbreeding depression even at fine spatial scales.

132 levels of inbreeding and reduced fitness via inbreeding depression, even as the population remained d

133 d no significant effect on the expression of inbreeding depression for above-ground dry mass.

134 Inbreeding depression for both species was low for all l

135 rovided by parents and alloparents mitigates inbreeding depression for early survival.

136 ns and compared mean fitness, heterosis, and inbreeding depression for eight large and eight small po

137 Seminatural conditions did not increase inbreeding depression for females, probably because fema

138 ced differences emerging in simulations with inbreeding depression for fitness.

139 We found significant inbreeding depression for germination rate (delta=0.33),

140 ., 12,000-65,000) will be required to detect inbreeding depression for likely effect sizes, and so st

141 quency of these major mutations, most of the inbreeding depression for male fertility and cumulative

142 These results suggest that most of the inbreeding depression for male fertility in this populat

143 tilocus heterozygosity, detected evidence of inbreeding depression for morphological traits.

144 population indicate that there is tremendous inbreeding depression for nearly every fitness component

145 Meta-analyses show that inbreeding depression for neonatal survival was signific

146 Significant inbreeding depression for pollen fertility was found in

147 e-sterility alleles contribute to 31% of the inbreeding depression for the fraction of viable pollen

148 n of viable pollen grains, and to 26% of the inbreeding depression for total fitness.

149 etween the neutral and selected loci and the inbreeding depression from the selected locus, irrespect

150 s inherent disadvantage are the avoidance of inbreeding depression generated by selfing and the abili

151 cly available computer program titled 'IDG' (Inbreeding Depression Genetics) to execute these procedu

152 pression by: (1) predicting the variation in inbreeding depression given arbitrary initial genetic va

153 nant role of semilethal alleles in embryonic inbreeding depression has implications for the evolution

154 inance was responsible for the observed high inbreeding depression, heterozygote advantage could not

155 If we are to understand the evolution of inbreeding depression (i.e., purging), we need quantitat

156 contribute to variability in the strength of inbreeding depression (ID) observed across adverse envir

157 The magnitude of inbreeding depression (ID) varies unpredictably among en

158 eduction in fitness-related traits, known as inbreeding depression (ID), yet the genetic and molecula

159 erimental designs typically used to estimate inbreeding depression (ID).

160 nbreeding measures commonly used to estimate inbreeding depression (ID).

161 The cost of inbreeding (inbreeding depression, ID) is an important variable in t

162 eterozygosity, which could increase risks of inbreeding depression if inbreeding subsequently occurs.

163 lower fertility; (ii) offspring suffer from inbreeding depression; (iii) parents have more grandchil

164 gest evidence to date of an HFC being due to inbreeding depression in a natural population lacking a

165 H regions can be used to predict the risk of inbreeding depression in a population.

166 is to provide information on the genetics of inbreeding depression in a primarily outcrossing populat

167 Here we investigate inbreeding depression in a range of life history traits

168 amounts to an approximately 69% increase in inbreeding depression in a stressful vs a benign environ

169 resolve the long-standing paucity of data on inbreeding depression in adult traits and total fitness.

170 and suggest that, to date, the prevalence of inbreeding depression in adult traits may have been unde

171 We also confirm previous findings of inbreeding depression in birth weight and juvenile survi

172 y, which revealed similar starting levels of inbreeding depression in both breeding systems, but also

173 We find evidence of inbreeding depression in both fitness metrics.

174 ing) influence the experimental evolution of inbreeding depression in Caenorhabditis elegans.

175 er, very little is known about the levels of inbreeding depression in dioecious species, obviously be

176 idence that purging can substantially reduce inbreeding depression in Gazella cuvieri (with effective

177 and comparatively complete pedigree detected inbreeding depression in juvenile survival, but not in a

178 The magnitude of inbreeding depression in L. jepsonii, although greater t

179 The models are most likely to detect inbreeding depression in large populations, that is, in

180 s for both the low mean and high variance in inbreeding depression in M. annua, and we discuss the im

181 Here, we report epigenetic links to inbreeding depression in maize.

182 There was no significant inbreeding depression in most traits due to one generati

183 to be ubiquitous among studies that examine inbreeding depression in multiple environments, and a pr

184 Data are presented on mating systems and inbreeding depression in multiple populations of two ann

185 tially recessive deleterious alleles causing inbreeding depression in natural plant populations.

186 , spatial genetic structure, and sporophytic inbreeding depression in natural populations of a dioico

187 eding provide a powerful tool for evaluating inbreeding depression in natural populations, and sugges

188 populations, and expand the understanding of inbreeding depression in natural subdivided populations.

189 es using modern genomic tools to investigate inbreeding depression in nature have been limited to sin

190 study were to: (1) quantify the strength of inbreeding depression in North-American populations of A

191 potentially leading to the lack of observed inbreeding depression in our study.

192 ous studies have suggested that early-acting inbreeding depression in plants is primarily due to leth

193 chromosomal regions have distinct effects on inbreeding depression in polyploids.

194 Parallel genome-wide screening of inbreeding depression in SCOURGE also showed an effect o

195 his hypothesis by comparing the magnitude of inbreeding depression in self-incompatible and self-comp

196 us to predict (1) reduced within-population inbreeding depression in small populations, which may be

197 is to identify the mechanisms and extent of inbreeding depression in small populations.

198 variation, create new species, and alleviate inbreeding depression in small populations.

199 t tool for mitigating detrimental effects of inbreeding depression in small, inbred populations, but

200 of new alleles-has been proven to ameliorate inbreeding depression in small, isolated populations, ye

201 s, and little is known about the dynamics of inbreeding depression in subdivided populations over tim

202 five loci with larger effects contribute to inbreeding depression in survival.

203 ny genetic disorders in humans and producing inbreeding depression in the majority of sexually reprod

204 y play an important role as a buffer against inbreeding depression in the offspring by alleviating th

205 Inbreeding depression in the selfer population, which na

206 um effective population size to avoid severe inbreeding depression in the short term is of the order

207 Biologists now recognize inbreeding depression in the wild, a phenomenon that wil

208 the coexistence of moderate selfing and high inbreeding depression in this strongly protandrous Silen

209 For age-specific mortality, the severity of inbreeding depression increased over the life span.

210 Inbreeding depression increases under stress in 76% of c

211 Inbreeding depression is a key factor in the maintenance

212 If inbreeding depression is caused primarily by recessive m

213 itness component and that almost all of this inbreeding depression is due to mildly deleterious allel

214 Inbreeding depression is due to the expression of recess

215 Inbreeding depression is expected to play an important b

216 Determining the genetic basis of inbreeding depression is important for understanding the

217 Understanding the genetic architecture of inbreeding depression is important in the context of the

218 Inbreeding depression is important in the evolution of p

219 mework describing the causes of sex-specific inbreeding depression is lacking, empirical evidence sug

220 reveals the important difference between how inbreeding depression is measured experimentally and how

221 Overall, the effect of inbreeding depression is more intense in men.

222 Experimental studies often find that inbreeding depression is more severe in harsh environmen

223 Inbreeding depression is most commonly expressed as comp

224 Inbreeding depression is of major concern for the conser

225 Inbreeding depression is one of the leading factors prev

226 Inbreeding depression is predicted to increase with age,

227 ife history could mean that the magnitude of inbreeding depression is routinely underestimated.

228 Inbreeding depression is the reduction in fitness of inb

229 Inbreeding depression is ubiquitous, but we still know l

230 Inbreeding depression is widespread across plant and ani

231 th America except in southern Florida, where inbreeding depression led to reproductive failure [3-5].

232 for all life history stages, with cumulative inbreeding depression less than 0.23 in all populations.

233 Our population models suggest that this inbreeding depression limits population growth and predi

234 llowing long-distance dispersal, declines in inbreeding depression may also be facilitated by genetic

235 Therefore, we identify two ways by which inbreeding depression may be underestimated in studies o

236 also reduces fitness and is a route by which inbreeding depression may operate, yet the complete path

237 ation among individuals in the expression of inbreeding depression may reflect lineage-specific diffe

238 Detailed studies suggest that the level of inbreeding depression may vary between populations.

239 Inbreeding depression, measured as the decline in fitnes

240 Taken together, these findings suggest that inbreeding depression negatively impacts the overall pat

241 ome size of Arabidopsis, and the equilibrium inbreeding depression observed in this highly selfing pl

242 Inbreeding depression occurs when inbred individuals exp

243 The low (<< 0.5) inbreeding depression of outcrossers suggests that the m

244 and short-term lowering of fitness owing to inbreeding depression, of which the latter appears the m

245 enotypes for 5952 wild Soay sheep to explore inbreeding depression on a key fitness component, annual

246 However, studies that directly translate inbreeding depression on fitness traits into consequence

247 In contrast, there was significant inbreeding depression only in flower number within self-

248 table mating states: outcrossing with strong inbreeding depression or selfing with weak inbreeding de

249 ulation decline, whereas projections without inbreeding depression or with default B suggested very g

250 ir conservation relevance to climate change, inbreeding depression, outbreeding depression and harves

251 rved wildlife species of Thailand, is facing inbreeding depression, particularly in the captive Siame

252 atophorum due to masking by early life cycle inbreeding depression, prevalent outcrossing, and ovule

253 In contrast, inbreeding depression primarily caused by many genes wit

254 and improvements in biomedical correlates of inbreeding depression, provide strong evidence that gene

255 have a multitude of negative effects such as inbreeding depression, reduced compatibility with wild s

256 Inbreeding depression refers to lower fitness among offs

257 We observed preliminary evidence for inbreeding depression related to stress caused by fungal

258 non-lethal mutations, reducing the amount of inbreeding depression relative to that expected without

259 t in captivity may decrease the intensity of inbreeding depression, relative to the stressful conditi

260 on, and degree of sex-specific difference in inbreeding depression remains enigmatic as studies on th

261 y enhancing genetic variability and reducing inbreeding depression, respectively.

262 In the absence of high levels of inbreeding depression, SC alleles are predicted to sprea

263 effects could have several causes, including inbreeding depression, shared incompatibility alleles, o

264 cists have been interested in inbreeding and inbreeding depression since the time of Darwin.

265 These findings could explain why inbreeding depression so frequently arises via compromis

266 of closely related parents often suffer from inbreeding depression, sometimes resulting in a slower g

267 In line with the prediction of sporophytic inbreeding depression sporophyte size was significantly

268 Together, these results suggest that inbreeding depression stemming from CSD has shaped matin

269 nding inconvertible evidence of the cause of inbreeding depression still presents a difficult challen

270 Here we show that inbreeding depression strongly influences the population

271 However, few previous inbreeding depression studies have considered longevity

272 ical, genetic, and demographic correlates of inbreeding depression, subsequently preventing extirpati

273 its retention is accompanied by substantial inbreeding depression, suggesting that it is caused by m

274 (ii) Polyploids exhibit less inbreeding depression than do their diploid parents and

275 ore relevant to selection and the purging of inbreeding depression than previous measures.

276 ctions with insects can increase or decrease inbreeding depression (the loss of fitness due to self-f

277 Inbreeding depression, the decline in fitness of inbred

278 important consequences for phenomena such as inbreeding depression, the evolution of diploidy, and le

279 iation in natural populations, the nature of inbreeding depression, the evolution of sexual reproduct

280 Inbreeding depression, the loss of offspring fitness due

281 Inbreeding depression, the reduced fitness of the offspr

282 eduction in fitness-related traits known as "inbreeding depression." There is mounting evidence that

283 lternatively, the partial dominance model of inbreeding depression typically applied to polyploids ma

284 ogeny; (iii) differing values of selfing and inbreeding depression using population means vs. matched

285 Statistical power to detect inbreeding depression using SNP data depends on the actu

286 70-85% using population means; in all cases, inbreeding depression values were high in early and late

287 Cumulative inbreeding depression was 76% for maternal families, and

288 h theoretical expectations, the magnitude of inbreeding depression was lower in L. bicolor, the more

289 large populations (mean = 7%, SE = 27); and inbreeding depression was lower, although not significan

290 rogeny were grown in a common greenhouse and inbreeding depression was measured in germination, survi

291 udy of Scots pine from Finland, the level of inbreeding depression was much lower in northern than in

292 Moreover, inbreeding depression was observed in eight of 11 offspr

293 -incompatibility or to extreme, early acting inbreeding depression, we performed three diallel crosse

294 tive ability of pollen, as well as levels of inbreeding depression, we predict that the early product

295 On average, significant levels of inbreeding depression were observed for median life span

296 as the potential to moderate the severity of inbreeding depression, which in turn may favor inbreedin

297 Inbreeding depression, which refers to reduced fitness a

298 tential cause may be environmental-dependent inbreeding depression with diet being one of the contrib

299 of standing variation for fitness traits is inbreeding depression, with its converse of heterosis or

300 terious mutations, reducing mean fitness and inbreeding depression within populations and increasing