ライフサイエンスコーパス: incentive salience

1 tion frames the dopamine signal as carrying 'incentive salience'.

2 istent with motivation-based theories (e.g., incentive salience).

3 e differences in cued approach behaviors and incentive salience.

4 nt operating rules that control motivational incentive salience.

5 ociated with these individual differences in incentive salience.

6 ent to which reward cues are attributed with incentive salience.

7 e degree to which the CS was attributed with incentive salience.

8 d 'motive circuit' only if it is imbued with incentive salience.

9 reward prediction error, working memory, and incentive salience.

10 ie motivated behavior and the attribution of incentive salience.

11 ional "wanting" component of reward, such as incentive salience.

12 that reinforcement will occur, or attributes incentive salience.

13 orcement learning, motivation, aversion, and incentive salience.

14 ative emotionality and elevated CRP, but not incentive salience.

15 ue to the cues having motivational value, or incentive salience.

16 d cues with incentive motivational value, or incentive salience.

17 by this food-specific circuit increases the incentive salience(13) of food cues, and thus facilitate

18 uitry that is involved in the attribution of incentive salience after repeated exposure to alcohol.

19 ERPs to show that these distractors acquire incentive salience and draw attention, but do not captur

20 at is caused by a combination of exaggerated incentive salience and habit formation, reward deficits

21 Addictions Neuroclinical Assessment domains incentive salience and negative emotionality were derive

22 n of key neurochemical circuits that mediate incentive-salience and/or reward systems (dopamine, opio

23 eward: 'liking' (hedonic impact), 'wanting' (incentive salience), and learning (predictive associatio

24 d signal enhancements for hedonic impact vs. incentive salience, and a faster firing pattern also dis

25 nisms related to hedonic evaluation of food, incentive salience, and control of motor feeding circuit

26 of reinforced behavior, such as motivation, incentive salience, and cost-benefit calculations.

27 ng effects of drugs of abuse, development of incentive salience, and development of drug-seeking habi

28 gions associated with executive functioning, incentive salience, and interoceptive processing in ciga

29 Three domains-executive function, incentive salience, and negative emotionality-tied to di

30 Sensitization therefore enhanced the incentive salience attributed to the CS+ even when rats

31 e, there were sex differences on measures of incentive salience attribution and sensation-seeking beh

32 l relationships between multiple measures of incentive salience attribution and, based on these findi

33 ntrol over the dopamine-dependent process of incentive salience attribution.

34 ned approach behavior (to obtain an index of incentive salience attribution; 'sign-tracking'), and su

35 n recent research suggesting that changes in incentive salience can alter the perception of time, as

36 That is, a cue's incentive salience can be recomputed adaptively.

37 itization of a neural system that attributes incentive salience causes compulsive motivation or "want

38 provide clues to a longstanding puzzle: how incentive salience, classical conditioning, emotional ar

39 The amplification of incentive salience did not require additional learning a

40 ability of reward cues to trigger "wanting" (incentive salience) for their associated rewards, indepe

41 different disorders of neural valuation and incentive salience formation, which helps bridge the gap

42 vlovian cues for rewards become endowed with incentive salience, guiding "wanting" to their learned r

43 o the dysregulation of functional domains of incentive salience/habits, negative emotional states, an

44 uture studies should investigate whether the incentive salience hypothesis allows for more accurate p

45 Consistent with the incentive salience hypothesis combining learned cue-rewa

46 In line with this incentive salience hypothesis, studies of human visual s

47 al domains associated with disinhibition and incentive salience in the etiology of PAI.

48 a form of stimulus-reward learning in which incentive salience is assigned to reward cues.

49 Incentive salience is thought to underlie key behaviors

50 PE) models suggest a role of learning, while incentive salience (IS) models argue that the DA signal

51 aser-paired porthole, suggesting that higher incentive salience made that cue more attractive.

52 ory, including motivation, prediction error, incentive salience, memory consolidation, and response o

53 ext, and also how reinforcement learning and incentive salience models may shed light on the disorder

54 e three factors, the factors corresponded to incentive salience, negative emotionality, and executive

55 be critical in the addiction cycle, namely, incentive salience, negative emotionality, and executive

56 rance in BD may be associated with increased incentive salience of cues and contribute mechanisticall

57 l hippocampal lesion resulted in the loss of incentive salience of cues in sign trackers.

58 NAc) shell dopamine (DA) levels modulate the incentive salience of discriminative stimuli that predic

59 er of behavioral symptoms including enhanced incentive salience of drug-associated cues, but also a n

60 This increased affinity may potentiate the incentive salience of food cues and counteract the effec

61 alatable (HP) foods, which in turn increases incentive salience of HP foods and allostatic load.

62 With enhanced incentive salience of HP foods and overconsumption of th

63 bic dopamine (DA) system (which mediates the incentive salience of natural and artificial rewards) an

64 pamine neurons of the VTA encode strength of incentive salience of reward cues.

65 Humans appear able to suppress the incentive salience of reward-associated objects when the

66 ulation of CeA magnifies and focuses learned incentive salience onto a specific reward cue (pavlovian

67 and motivation for sucrose-paired cues (ie, incentive salience or 'wanting').

68 signals in shell to generate either positive incentive salience or negative fearful salience (valence

69 Incentive salience, or 'wanting', is a type of mesolimbi

70 lthough previous work implicated the CeMA in incentive salience, our results isolate the investigatio

71 ating phasic firing patterns associated with incentive/salience paradigms.

72 ated with arousing stimuli acquire increased incentive salience, processes mediated in part by the nu

73 pamine neurons are thought to convey a fast, incentive salience signal, faster than can be mediated b

74 smission may be the initial component of the incentive salience signal.

75 hell DA levels, nor the resultant changes in incentive salience signaled by this structure, impact te

76 llidum neurons, and likewise, they increased incentive salience signals in firing to the reward-proxi

77 th sleep regulation and the effects on brain incentive salience systems, such as dopamine.

78 ormation via dopamine-dependent, cue-driven, incentive salience systems.

79 d can acquire motivational properties (i.e., incentive salience) that cause them to have a powerful i

80 ls of learning in the basal ganglia with the incentive salience theory in a single simple framework,

81 with proposed roles in reward prediction and incentive salience, these results indicate that rapid do

82 We quantified the attribution of incentive salience through cue approach behavior and cue

83 To this end, the propensity to attribute incentive salience to a food cue was first assessed in t

84 by variation in the propensity to attribute incentive salience to a food cue.

85 e individual variation in the attribution of incentive salience to both food- and social-related cues

86 Research on the attribution of incentive salience to drug cues has furthered our unders

87 nsitized leading to excessive attribution of incentive salience to drug-associated cues.

88 ted, in part, to the propensity to attribute incentive salience to food cues, which, in turn, contrib

89 less (goal-trackers; GTs) prone to attribute incentive salience to food reward cues.

90 d cues (conditioned stimulus [CS]) also gain incentive salience to promote drug seeking.

91 rain region where environmental cues acquire incentive salience to reinforce motivated behaviors.

92 uals who have a propensity to attribute high-incentive salience to reward cues also exhibit relativel

93 In addition, the propensity to attribute incentive salience to reward cues can predict the propen

94 ual variation in the propensity to attribute incentive salience to reward cues predicts variation in

95 traits, such as the propensity to attribute incentive salience to reward cues that is modeled in rat

96 ers (STs)] are especially prone to attribute incentive salience to reward cues, relative to others [g

97 [sign-trackers (STs)] are prone to attribute incentive salience to reward cues, which can manifest as

98 ual variation in the propensity to attribute incentive salience to reward cues.

99 e release is critical for the attribution of incentive salience to reward cues.SIGNIFICANCE STATEMENT

100 individual differences in the attribution of incentive salience to reward predictive cues, that is, s

101 e for dopamine neurons in the attribution of incentive salience to reward-paired cues, and underscore

102 are the tendency of STs and GTs to attribute incentive salience to social reward cues as well as form

103 Compared to GTs, STs attributed more incentive salience to social-related cues and exhibited

104 In the brain, dopamine (DA) provides incentive salience to stimuli that predict the availabil

105 Confirming modulation of incentive salience, unconditioned food intake was simila

106 cious pleasure) and (3) motivation (implicit incentive salience 'wanting' and cognitive incentive goa

107 erdopaminergic mutant mice attribute greater incentive salience ("wanting") to a sweet reward in the

108 effect on dependence-related alterations in incentive salience/'wanting'.

109 ectroencephalography, a recognized marker of incentive salience, was used to track motivated attentio

110 To reveal the focusing of incentive salience, we exploited individual differences