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1 ressure in Patients with ACS and OSA) study, including 1,701 patients admitted for ACS (NCT01335087).
2 olled harmoniously by two counteracted teams including (1) auxin/indole-3-acetic acid (AUX/IAA)-histo
4 he trial to receive genotype-matched therapy-including 14 that re-registered to the trial for a seque
6 rmance of this method in a multicenter study including 16 teaching hospitals in the United States (n
7 ematological traits in 746,667 participants, including 184,535 non-EUR individuals, we identified 5,5
8 ed CsGA1ox/ds) performed multiple reactions, including 1beta-oxidation and 9,11-desaturation of GAs,
11 es to identify key ACE2 amino acid positions including 30, 83, 90, 322, and 354 that distinguish susc
12 re determined for 610 Gram-negative bacilli, including 302 multinational Enterobacterales isolates wi
15 es of SJLIFE survivors of European ancestry, including 34 nonirradiated male survivors treated with 0
16 s to calibrate for 6 different RO membranes, including 4 brackish water and 2 seawater membranes.
18 ith an average 1.7 HBR criteria per patient, including 60.7% >75 years of age, 34.1% on anticoagulant
19 rait-variant associations at p < 5 x 10(-9), including 71 novel associations not found in EUR populat
20 1447 patients were enrolled across the VCs, including 737 in the standard care group and 710 in the
21 a large database of complete viral genomes, including 76,262 identified from a systematic search of
23 istinctive pathways and clinical correlates, including a group closest to HFrEF with higher mortality
24 omplexes with distinct molecular assemblies, including a megadalton-scale tRNA multi-synthetase compl
25 that were missed by Illumina-based methods, including a novel micropia-like element that has recentl
26 mixed-effects linear or logistic regression, including a random effect to adjust for within-school cl
27 EAE that may contribute to these phenotypes, including a reduction in adult locomotor activity, alter
28 structure-permeability trends were observed including a relationship between alternating stereochemi
29 governance structure to support innovation, including a robust framework for environmental risk asse
30 based on a receptor-driven docking model and including a systematic free energy perturbation (FEP) st
31 ylation rates were significant at low light (including above the Kok break point) and increased with
33 uld target a wide range of relevant factors, including ACEs, socioeconomic deprivation, parental subs
35 opathological reevaluation of these biopsies including additional features of ATI, we developed a fin
36 ferential biophysical and functional changes including, adhesion and migration in EOC-derived fibrobl
37 m3/Tof1 and Mrc1), which has important roles including aiding normal replication rates and stabilizin
39 Mixed-methods identified treatment barriers including, alcohol abuse, family conflicts, and mental h
40 nent material (aliphatic hydrocarbon resin), including alkanes, fatty acids, amides, and tackifying t
41 ecruited from 119 public primary care units, including all 26 state capitals and the Federal District
42 l definition of CLL subset 2 to subset 2L by including all IGLV3-21(R110)-expressing CLL cases regard
45 d tumor-specific non-canonical HLA peptides, including an immunogenic peptide derived from an open re
47 unique structure and coordination chemistry including an unusual tridentate coordination effect of 1
48 macrophage metabolism during heart failure, including antidiabetic therapies, anti-inflammatory ther
52 was described by using linear mixed models, including biomarker [log10(P/B ratio) and/or AMY1 CN] di
53 ords high-throughput analyses of antibodies, including bispecific antibodies and potential mispaired
54 T16 clone carried up to 14 resistance genes, including blaKPC-2 in an IncFIBpQIL plasmid, KL51 capsul
55 enal structures: glomerular tuft, glomerulus including Bowman's capsule, tubules, arteries, arterial
57 onfirmed it as a potent inhibitor of kinases including BRSK1 and BRSK2 that were identified in the or
58 intra- and extra-cellular stress conditions including, but not limited to, pathogen intrusion, oxyge
62 lated multi-drug-resistant bacteria strains (including carbapenem-resistant Escherichia coli and meth
63 sses and in various pathological conditions, including cardiovascular disease, cancer, diabetes and c
64 Women with inherited bleeding disorders, including carriers of hemophilia A and B, or with von Wi
66 traditional light-sheet microscope geometry, including cell migration through confined spaces within
67 ic lifestyle showcases distinctive features, including cellular asymmetry and differentiation during
68 inhibit several mesenchymal-like properties including cellular invasion and colony formation in vitr
69 nd extrinsic) triggered by multiple factors, including cellular stress, DNA damage and immune surveil
70 ts in many organ-specific fatal pathologies, including cerebral malaria (CM), driven by a high parasi
71 the Western diet promotes tumor recurrence, including changes in the microbiome, in mice that underw
72 drug platforms, focusing on key approaches - including chemical modification, bioconjugation and the
73 cell level is urgently needed in many fields including clinical diagnosis and environmental microbiol
74 nst NTRK gene fusion-positive solid tumours, including CNS activity due to its ability to penetrate t
75 xity of interacting environmental stressors, including CO(2), temperature, light, and nanoplastics.
77 ces, deep-learning machine learning methods, including convolutional neural networks, have enabled th
78 of proteins containing polyglutamine tracts including core-binding factor alpha1, mediator subunit 1
82 ultiple factors associate directly with CMG, including Ctf4 and the heterotrimeric fork protection co
85 g other sources of 'artificial' confounding, including cyclical oscillations of the 'dirty-cage/excre
86 aenoic acid (EPA), and (2) the enzyme group, including cyclooxygenase (COX), lipoxygenase (LOX), or c
87 paired hallmarks of inflammation resolution, including dampening of the T helper 1 response, alternat
88 emographic and clinical data were collected, including data on clinical management, respiratory failu
90 studied under several intersecting umbrellas including decision-making, action selection, perceptual
91 oncentrations of upstream lysine metabolites including Delta1-piperideine-6-carboxylic acid (P6C), al
92 our understanding of secular trends of EGS, including demographics, diagnoses, operations, and outco
93 urred in the ability to study sleep in dogs, including development of non-invasive polysomnography; h
95 ions in several gene families in J. hindsii, including disease resistance-related wall-associated kin
96 to defects in diverse biological processes, including DNA damage repair (Fanconi anemia), telomere m
97 SCs) occasionally acquire mutations in genes including DNMT3A that enable them to outcompete other HS
98 ayonnaises were analyzed based on parameters including droplet size, viscosity, peroxide value, volat
99 to clinical attention in a variety of ways, including during the evaluation of a possible hematologi
100 nt separated anterior insula manifestations, including early hypermotor signs, early recovery, and no
101 an ensemble of state-of-the-art fire models, including effects of land use and the ensemble median or
102 Twenty nine cinnamoylquinic acids (CiQA), including eight mono-CiQA, fourteen di-CiQA, and five tr
104 tions with robust mucoinflammatory features, including elevated expression of Th2-associated markers
105 addition to well-known secondary metabolites including emodin, aloe-emodin, beta-sitosterol and rutin
106 ndary amines may be inserted by this method, including enantiomerically pure amino acids, enabling us
108 fferent SARS-CoV-2 lineages into California, including epidemic WA1 strains associated with Washingto
109 with other comorbidities have been reported, including erectile dysfunction, atrial fibrillation, obs
111 evelopment of high-energy-density materials, including explosives for defense and construction purpos
112 as required for AvrPtoB virulence functions, including facilitating bacterial colonization, suppressi
113 the identification of similar abnormalities including fewer satellite cells, fewer dividing cells, a
114 usly showed that no classic model of vision, including ffCNNs, can explain human global shape process
116 d inhibition values between hsTYR and abTYR, including for widely used standard tyrosinase inhibitors
117 Bacterial dormancy can take many forms, including formation of Bacillus endospores, Streptomyces
118 layer in many neurodegenerative pathologies, including frontotemporal lobar degeneration (FTLD) and a
119 d 3.0 at differing infection rate scenarios, including full suppression (0.001%), partial suppression
120 venues for continued scientific exploration, including further elucidating of the genetic pathway of
122 reviously identified novel eNOS interactors, including G protein-coupled receptor (GPCR) kinase inter
123 way is dysregulated in several malignancies, including gastric cancer, and is an important biomarker
124 pulation for genes central to calcification, including genes for calcium management (calmodulin, calc
125 ent in genes localizing to the mitochondria, including genes involved in mitochondrial translation.
127 exhibit a wide range of physical properties, including giant Rashba spin splitting and anomalous Hall
128 nts deficient in central metabolic pathways, including glycolysis, gluconeogenesis, the tricarboxylic
131 L]), inflammatory, and antioxidant (enzymes, including heme oxygenase isoforms [HO-1, HO-2]) markers.
132 lication of several other pathogenic viruses including Herpes Simplex Virus-1 and-2, Vaccinia virus,
134 arent conducting electrode (TCE) properties, including high electrical conductivity (~11 670 S cm(-1)
135 by insults, which mimic the diabetic milieu, including high glucose and/or fatty levels, and by the a
136 detection limits to-date for many compounds, including highly toxic iodinated, brominated, and nitrog
137 re was no consensus on the relevance of REA, including how each of these measures should be used in d
139 aphical origin of diverse biological species including humans and proteomic data to classify breast c
140 ere used to identify condition at admission, including hypotension, Glasgow Coma Scale, mechanism and
141 y quantifying multiple endogenous compounds, including IBC, thiamine, N(1)-methylnicotinamide (1-NMN)
142 afted, induced release of multiple cytokines including IL6, IL17, MCP-1, and GM-CSF in the tumor-bear
144 possess superior pharmacological properties, including improved resistance to enzymatic degradation,
146 cally significant difference between groups, including in-hospital mortality (1.7% for uncemented fix
147 mice also displayed multiple airway changes, including increased branching (59%; P < 0.001), increase
148 ronal and network excitability after injury, including increased susceptibility to spreading depolari
150 l discuss the modes of action by those drugs including inducing innate sensing and limiting immunosup
151 r a cure to many P2X7-dependent pathologies, including inflammatory, neurological, and immune disease
152 with the protein was measured by techniques including isothermal calorimetry analysis, fluorescence,
153 isarticulated skull of the large morphotype, including its endocast and inner ear, to reveal its morp
155 avefront dynamics of key nonlinear processes including Kerr self-focusing, ionization and plasma defo
156 d, we observed a reduction in a subset of 8, including key components of the nuclear pore complex sca
157 HGT events from diverse angiosperm lineages, including large and recent transfers from the Asteraceae
158 ermines environmental productivity patterns, including large-scale variability in pathogens, vectors
159 nfavourable conditions associated with stone including limited sources of nutrients and water, high p
160 ay, defined by (1) the fatty acid precursor, including linoleic acid (LA), arachidonic acid (AA), doc
162 nd additional catalytic activities of SIRT6, including long-chain deacylation and mono-ADP-ribosylati
164 populations due to a combination of factors including low concentrations of bioavailable dissolved U
165 cating them in many diseases besides cancer, including lung, renal, and neurodevelopmental disorders.
166 tion by methods routinely used for bacteria, including matrix-assisted laser desorption/ionization ti
167 those of coexisting bacterial methanotrophs, including members of Methyloparacoccus, Methylocystis an
168 (PrEP) regimens among high-risk populations, including men who have sex with men (MSM) and transgende
169 It currently hosts 298 reference pathways, including metabolic and transport pathways, transcriptio
170 metalloclusters in diverse application areas including metal organic framework design, TM-based catal
174 Changes in expression of some microRNAs, including miR-17, miR-150, and miR-155, suggested that m
175 miRNA families involved in T2D pathogenesis including miR-200, miR-7, miR-184, miR-212/miR-132, and
177 It provides new pharmacological content, including molecular targets in the malaria parasite, int
178 corroborative evidence from multiple levels including molecular, brain, and behavioral indicates tha
179 ransporter of mycolic acid-containing lipids including monomeromycolyl diacylglycerol (MMDAG), mycola
180 tivates transcription of key protooncogenes, including MYC We report that BRD4 phosphorylates MYC at
182 in cells of the developing cerebral cortex, including neural progenitor cells and developing neurons
183 pansions of 41 out of 44 pathogenic repeats, including nine recently reported non-reference repeat ex
184 es from patients treated for symptomatic CAD including non-ST elevation MI, along with healthy age-ma
185 developments in understanding TIM3 biology, including novel ligand identification and the discovery
188 fference within different types of glaucoma, including open-angle glaucoma (P = 0.36), chronic angle
190 ent developments and technical breakthroughs including optical, electrochemical and electrical biosen
191 ray of subdisciplines of inorganic chemistry including organometallic chemistry, bioinorganic chemist
192 ifferentiate into various lineages in vitro, including osteogenic, chondrogenic, and adipogenic linea
194 tionship between different particle metrics, including particle number (PNC), length (PLC), and surfa
195 is the generation of heat, for applications including passive building heating, but it can also driv
196 re activated in response to diverse stimuli, including pathogen-associated molecular patterns (PAMPs)
197 Those still receiving treatment at 1 year, including patients perceived to be deriving benefit desp
200 Hallmarks of human disease were observed including petechial rash, blood coagulation dysfunction,
201 eate materials relevant to energy challenges including photoconductors and supercapacitors are also d
203 ies conducted mainly in large-animal models, including pigs, rabbits, dogs, and nonhuman primates.
205 ve pervasive impacts on native biodiversity, including population extirpations and species extinction
209 time (2.3 mo) and extensive prior treatment, including prior docetaxel (84%), cabazitaxel (48%), and
210 hybrid compounds derived from colchicinoids including prodrugs, conjugates, and delivery systems.
211 PML) bodies, sites of many nuclear processes including protein quality control of nuclear aggregates.
213 tolerant of a wide range of functionalities, including rarely reported quaternary nitroalkene substit
214 ysis examined factors related to initiating (including re-initiating) ART in the hospital and its ass
215 e NRE is impacted by extreme weather events, including recent increases in precipitation and flooding
216 using components of the necroptotic pathway, including receptor-interacting protein kinase-3 (RIPK3),
217 ly attenuates the neurodegenerative process, including reduced Abeta accumulation as well as tau hype
218 to accommodate these environmental changes, including regulation of mRNAs that require extensive uri
220 ional neural network-based image processing, including relative area under the curve accumulation, ti
222 s a number of endosomal trafficking pathways including retrograde transport to the trans-Golgi networ
224 rentially expressed and/or methylated genes, including RPS27L, were associated with pulmonary functio
225 on of lysozyme-sensitive mucolytic bacteria, including Ruminococcus gnavus, a Crohn's disease-associa
226 es exhibit strong interpeptide interactions, including salt bridges, H-bonds, and polar interactions.
227 ty health centers in March through May 2020, including SARS-CoV-2 testing, well-child visits, HbA(1c)
229 a diverse array of ECM-associated proteins, including secreted factors and modulators of the matrix.
230 s analyzed right-eye vitreoretinal findings, including semiautomated quantification of punctate hyper
231 tains multiple concurrent precursor lesions, including serous tubal intraepithelial carcinoma (STIC),
233 e contraception when contraceptive services, including short- and long-acting methods, are available,
234 al life history-relevant variables measured (including short- vs. long-term sexual strategy, temporal
235 otypic and biochemical evidence of GH excess including significantly elevated insulin-like growth fac
236 We apply this strategy to various substrates-including silicon, ceramic, metal and transparent glass-
237 brain neuropils and 30 neuronal fiber tracts including six distinct tracts between the optic lobes an
238 performance of all machine learning models, including six other algorithms, was evaluated by interna
239 practical utility of an integrated approach, including size exclusion chromatography with multiangle
240 associated with a number of T-cell diseases, including some peripheral T-cell lymphomas, hemophagocyt
241 nating but poorly understood branch of life, including species with a highly unusual body plan and a
242 argets DPC protein moieties for degradation, including stabilized topoisomerase-1 cleavage complexes
243 ccessible Ullmann-Goldberg coupling products including sterically demanding ortho-substituted heteroa
244 line parental questionnaire, clinical visits including structured interviews and skin prick tests (SP
246 sures by all stakeholders active in the APR, including surveillance for species such as those identif
248 te that more than ten fundamental equations, including that of classical mechanics, fluid physics, st
249 Protein factors that mediate both processes, including the 5'-3' exonuclease Xrn1, are responsible fo
250 ions are determined by a lumenal pH of ~5.0, including the activity of resident acid-activated hydrol
254 disease in various human tissues and organs, including the ear, the brain, the blood, and the lung, a
255 ompanied by new adaptations to life on land, including the evolution of stomata-pores on the surface
256 with those of the state-of-the-art DL models including the fully convolutional network (FCN), SegNet,
257 ystem takes place in all biological systems, including the human body, but this interaction is especi
259 ns facing greater implementation challenges, including the nations of Central Africa, where efforts m
260 to interact with diverse types of receptors, including the neonatal Fc receptor (FcRn) and Fcgamma re
261 res, whereas others have unusual attributes, including the nepenthesin loop of plasmepsin V and a his
262 milies who are the most at risk, and factors including the openings of some schools, are considered.
263 ce neurotoxicity through multiple mechanisms including the oxidative stress, DNA damage, lysosomal dy
264 in defects to anterior embryonic structures, including the pharyngeal arches, heart, and anterior som
265 gave responses of similar magnitude to ATP, including the previously identified agonists ATPgammaS a
268 Pase from bovine brain with all the subunits including the subunit H, which is essential for ATPase a
269 llular signaling through multiple receptors, including the T-cell receptor (TCR), co-receptors, and c
270 h respect to all other secondary end points, including the time to first symptomatic skeletal event a
272 could benefit from this convenient approach, including the use of versatile, reduced-format mass spec
274 The m7GHub consists of four main components, including: the first internal mRNA m7G database containi
275 d light on various aspects of these enzymes, including their structure, mechanism, alternative reacti
276 example, conserved molecular thermosensors, including thermosensitive channels and receptors, act as
277 rongest drivers of interkingdom interactions-including those between microorganisms and their multice
279 Ala substitutions for most alphaM4 residues, including those in clusters of polar residues at both th
280 hrough the crust and much of the subsurface, including those microbial ecosystems located within cave
281 , we identified different organic P species, including those not identified by the common P K-edge XA
282 trimental myeloid cell responses in tissues, including those occurring in the persistently inflamed c
283 xperimental findings and theoretical models--including those of our own--in the field, and indicate t
285 nicity by increasing transcription of genes, including those that lead to cellular accumulation of pr
286 osis, suggesting that concurrent mechanisms, including those traditionally associated with HRS-1 and
287 he application of adoptive T cell therapies, including those using chimeric antigen receptor (CAR)-mo
288 sk because of sensitization to alloantigens, including those who have exhibited early onset or accele
289 of advanced-stage prostate cancer patients, including those with SPINK1-positive subtype, are treate
291 red three independent introductions of rats, including to Suouroy, the islands of Borooy and Viooy, a
292 The influence of various assembly parameters including type of mixing solvent, substrate temperature,
293 s are harmonized by common biological themes including up-regulation of nutrient transporters, down-r
294 d procedural characteristics were collected, including valve implantation depth and membranous septum
295 wide array of polycyclizations are achieved, including variants that involve powerful dearomatization
296 ts that mediate the associated pathogenesis, including vascular dysfunction, thrombosis, dysregulated
297 a single application of basaltic rock dust, including via newly formed soil carbonate minerals whose
298 apist according to an intervention protocol, including virtual reality video games, activity monitors
299 ocations, producing a series of vdWH arrays, including VSe(2)/WSe(2), NiTe(2)/WSe(2), CoTe(2)/WSe(2),