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1 LDH) and was oxidative in nature as shown by increased expression of 8-hydroxydeoxyguanosine (8-OHdg,
2 onsistent with this explanation, we observed increased expression of a GABA transporter, GABA transpo
3 in refractive index in the lens nucleus and increased expression of a particular crystallin protein
5 MLL1) gene rearrangement is characterized by increased expression of a set of homeodomain transcripti
6 risk for schizophrenia and bipolar disorder, increased expression of a ST3GAL3 transcript with risk f
7 VEP is sensitive to changes mediated by the increased expression of alpha-synuclein and especially w
8 compared to naive MDSC control, evMDSC have increased expression of an anti-angiogenic factor thromb
9 pt with risk for schizophrenia and ADHD, and increased expression of an XPNPEP3 transcript with risk
10 iated reduction in drug sensitivity involves increased expression of antiapoptotic proteins and susta
11 ic survivors, nonsurvivors had significantly increased expression of any checkpoint molecule on any c
12 ney HEK293 cells and examined the effects of increased expression of APOL1 (G0, G1, G2, G0G0, G0G1, o
14 ical analysis of the mouse brain revealed an increased expression of aquaporin4 (AQP4) in the flight
17 anced Zip14-dependent zinc uptake by muscle, increased expression of Atrogin1 and MuRF1 and markedly
18 of Ras, inhibition of Akt/mTOR pathways, and increased expression of autophagy markers, leading to an
19 d cell growth and induced apoptosis and also increased expression of Bax as well as cleaved caspase-3
20 increased brain capillary pericyte density, increased expression of BBB tight junction proteins, red
22 ersus tumor-infiltrating monocytes and found increased expression of both pro- and anti-inflammatory
23 eads that could not pass the plasma membrane increased expression of both TCSn::GFP and Cytokinin Res
25 SIK1) stabilized the deacetylase, leading to increased expression of c-Myc, which in turn stimulated
27 RBalpha, and deletion of REV-ERBalpha causes increased expression of C4b transcript in neurons and as
29 d with amplification of Myc target genes and increased expression of canonical Wnt signaling in treat
32 n AAA tissues obtained from surgery revealed increased expression of CCR2 that was co-localized with
33 g repertoires as a result of infection, with increased expression of CD103 in colon NK cells and curt
35 cells (Tregs), in contrast, demonstrated an increased expression of CD28 with aging and CTLA4-Ig tre
38 , CRP level was 12.5mg/dl and the remarkably increased expression of CD64 on neutrophils was found.
41 ylation, aberrant metabolic profiles, and an increased expression of chemokines, indicative of a pers
42 NA-sequencing of DAC-treated tumors revealed increased expression of Chi3l3 (Ym1), reflecting an incr
43 tedly, RNAseq analysis revealed dramatically increased expression of cholecystokinin (CCK) in regener
46 hosphorylation state, as demonstrated by the increased expression of Collagen-I by HSCs incubated wit
48 CD11c(+) cells from Sema3E KO mice displayed increased expression of costimulatory molecules and IL-1
49 ation of mouse, human, and porcine APC, with increased expression of costimulatory molecules and secr
50 the brain may increase risk to SCZ only and increased expression of CSE1L is associated with SCZ and
51 criptomic analysis linked elevated injury to increased expression of Cybb, the gene encoding the cata
53 ployed a model of murine BSM tissue in which increased expression of desmin or vimentin was induced b
55 key second messengers (SMAD-1/5/9) and also increased expression of direct target genes (inhibitors
57 reatment of MDSC-like cells activated STAT3, increased expression of DNMT1 and DNMT3b, and enhanced s
58 migraine trigger, nitroglycerin, we observed increased expression of DOR in cortex, hippocampus, and
60 a result of tumour cell re-wiring leading to increased expression of EGFR, MAPK, CDK4, CDK2, CDK7, CC
65 staining of joints from the HFD group showed increased expression of ER stress and apoptotic markers
67 Breast cancer progression is accompanied by increased expression of extracellular and cell-surface p
68 esistance but increased cell migration, with increased expression of extracellular matrix-related gen
69 and the transcriptomic level, indicated that increased expression of factors such as interferon-gamma
71 from smokers and subjects with COPD display increased expression of ferroportin as well as hepcidin.
73 ed skeletal muscles, which were confirmed by increased expression of fibroblast growth factor-inducib
74 alpha -> nuclear factor kappaB -> caspase-3, increased expressions of fibrosis-related proteins inclu
77 ion of primate-conserved LINE-1s, as well as increased expression of full-length hominid-specific LIN
78 nerating crypts from patient biopsies showed increased expression of Gal-9, indicating these processe
79 otrophic factor (GDNF) in injured muscle and increased expression of GDNF family receptor alpha1 (GFR
81 e WT EBV- versus Delta3A-infected tumors and increased expression of genes associated with T cells, s
82 eq and quantitative RT-PCR analyses revealed increased expression of genes associated with tumor cell
83 Livers of Nod2(-/-) tumorigenic mice had increased expression of genes involved in cell prolifera
84 ssion revealed that downregulation of Rab27a increased expression of genes involved in epithelial-to-
85 ng the pancreas of humans with T1D exhibited increased expression of genes located on misfolded loci
86 ced B cell IgA production in vitro, with the increased expression of genes related with class-switchi
87 r overnight fasting, BAT lacking ALK7 showed increased expression of genes responsive to nutrient str
88 educed EZH2 mRNA and protein levels but also increased expression of genes silenced by EZH2, such as
89 tissues from patients with liver disease had increased expression of genes that define PMC identity c
90 Expansion of tuft cells was associated with increased expression of genes that regulate the tricarbo
92 th primary muscle afferent sensitization and increased expression of glial cell line-derived neurotro
93 enitor cells promotes cell proliferation and increased expression of glial markers and glia-enriched
94 ation of mutant TLR4 marrow cells results in increased expression of gluconeogenic genes and impaired
95 (GRM1(+)) melanomas exhibited significantly increased expression of glutaminase (GLS), which catalyz
96 ncreased levels of glycolytic intermediates, increased expression of glycolysis genes, and increased
98 blood glucose levels that is associated with increased expression of hepatic gluconeogenic enzymes in
99 /-) mutant zebrafish exhibited significantly increased expression of hepatocyte markers with no impac
101 This loss of activity was associated with increased expression of histamine degrading enzymes and
102 steoarthritic samples, which correlated with increased expression of HS6ST1, a 6-O-sulfotransferase,
103 Stimulation of fibroblasts with TGFbeta1 increased expression of HVEM; subsequent stimulation wit
104 -gamma production in mesenteric lymph nodes, increased expression of Ido1 in the cecum, and a complet
105 nflammatory response that is associated with increased expression of IFN-beta and other IFN-related g
107 er of bronchoalveolar lavage eosinophils and increased expression of IL-13 mRNA but not expression of
108 ay 6 before RV-A2 infection on day 13 showed increased expression of IL-13, IL-5, Gob5, Muc5b, and Mu
113 g shotgun metagenome sequencing and observed increased expression of immune-modulating microbiota, su
114 -induced mice demonstrated that Hh signaling increased expression of immunoregulatory genes and reduc
115 ponse (UPR) components, which coincides with increased expression of inflammasome components, recruit
116 86 with a serine (VbrK C86S mutant) leads to increased expression of inflammatory cytokines in infect
118 NMT3A mutations demonstrated a significantly increased expression of inflammatory genes compared with
119 st commonly found mutations in CHIP, lead to increased expression of inflammatory genes in innate imm
120 transfected to overexpress LPCAT2 exhibited increased expression of inflammatory genes in response t
121 tory receptor Ly49D on educated NK cells and increased expression of inhibitory receptor NKG2A/CD94 o
122 share a common core phenotype including the increased expression of inhibitory receptors, associated
123 uppressed by the tumor microenvironment, and increased expression of inhibitory receptors, including
124 firmed decreased ERBB3/ERBB4 while revealing increased expression of insulin-like growth factor recep
125 [LLV]) or point mutations in Lpro result in increased expression of interferon (IFN) and IFN-stimula
126 g, we reveal rapid viral replication and the increased expression of interferon-associated genes and
127 patient compared with his normal skin showed increased expression of interferon-gamma and chemokines
128 ion and interleukin-1 signaling pathways and increased expression of interferon-induced protein with
131 Cox proportional hazard ratio, we found that increased expression of K17 at the IHC level is also ass
132 nontarget microRNA control ZIKV demonstrated increased expression of key cytokines and chemokines cri
133 levated extracellular acidification rate and increased expression of key glycolytic genes (GLUT1, HK2
134 inct in young and older adults; for example, increased expression of killer cell lectin-like receptor
135 bility of release associated with an overall increased expression of L-type voltage-gated Ca(2+) chan
136 human ortholog of MaTAR25, and importantly, increased expression of LINC01271 is associated with poo
137 n revealed that rs2242367 is associated with increased expression of LRRK2 and two long intergenic no
139 ls results in activation of beta-catenin and increased expression of lymphoid enhancer-binding factor
140 s and Sjogren's syndrome patients identified increased expression of lysosome-associated membrane pro
141 cterized by decreased expression of NRF2 and increased expression of MAFG, which cooperates with MAT2
142 onse to cornea debridement wounding, we find increased expression of MAGP1 throughout the central cor
143 nd that NPCs cultured in BrainPhys displayed increased expression of markers for cortical deep-layer
144 nts during HSC activation and accompanied by increased expression of markers of fibrogenesis; incubat
145 o ductal metaplasia, stem cell features, and increased expression of markers of the epithelial-mesenc
146 llagen due to impaired TGFbeta signaling and increased expression of matrix metalloproteinases drivin
147 quencing of engrafted hESC-CMs confirmed the increased expression of matured ventricular cardiomyocyt
150 hagocytic states, such as IL-6 and IL-4, and increased expression of microglial chemokines, such as m
151 on the promoter region of miR-1185-1, which increased expression of miR-1185-1 and further repressed
153 nterocytes isolated from mice given IL1B had increased expression of MIR200C-3p and decreased levels
155 nt accumulation of pyruvate, corroborated by increased expression of mitochondrial enzymes and transp
156 tomas with MYCN amplification, 17q gain, and increased expression of mitochondrial ribosome and elect
159 ssues progressed from BE to HGD to EAC, they increased expression of mRNAs encoding isoform 1 of RNF1
160 ogressive fibrosis and bronchiolization with increased expression of Muc5b in peripheral airways, hon
161 tory response in the lungs, characterized by increased expression of multiple inflammatory markers an
162 igodendrocyte precursor cells (OPCs) rapidly increased expression of myelin genes and myelin proteins
163 maternally separated (MS) pups identified an increased expression of myelin-related genes and a decre
164 rived from JAK2V617F erythrocytes identified increased expression of myeloperoxidase as the likely me
169 with decreased GULP1 expression, we observed increased expression of NRF2, HMOX1, and other candidate
170 ssion of ER stress and apoptotic markers and increased expression of nuclear protein 1 and tribbles r
173 rrupt protein-coding genes, resulting in the increased expression of one gene and modest truncation i
174 tance to pathogen infection accompanied with increased expression of one-third of the 207 NLR genes i
178 splayed excess mitochondrial fission and had increased expression of PDK isoforms 1 and 3 that persis
180 utic biomarker for cancer are limited due to increased expression of periostin in non-cancerous infla
182 addition, Hipk2 (-/-) neurons and MEFs show increased expression of PGC-1alpha (peroxisome prolifera
183 ns and mouse embryonic fibroblasts also show increased expression of PGC-1alpha (peroxisome prolifera
186 /16-1 and MYO1C in TFEB-depleted cells cause increased expression of plasma membrane VEGFR2, but in a
187 motherapy induces BCSC specification through increased expression of pluripotency factors, but how th
189 e membrane depolarization and calcium influx increased expression of primiR-199a2 but not of primiR-1
190 violet light exposure and is associated with increased expression of pro-cancer genes and reduced exp
192 Chronic tendinopathy was associated with increased expression of pro-inflammatory markers PTX3, C
193 DHA-deficient mice were characterized by an increased expression of pro-inflammatory molecules, name
198 on and proliferation of human aortic SMC and increased expression of proinflammatory molecules and ac
200 HIF1A-knockout pancreatic cancer cells had increased expression of protein phosphatase 1 regulatory
201 yses revealed that genetic silencing of TBK1 increased expression of proteins and genes essential for
206 s (including those involved with pectin) and increased expression of putative cellulose synthases ind
207 d FGFR siganalling in osteoblasts, including increased expression of RANKL, M-CSF, and osteoprotegeri
208 igh-fat diet-fed ApoE(-/-) mice displayed an increased expression of Rap1 both in aortas and circulat
210 These findings are further substantiated by increased expression of S100A8 and S100A9 mRNA in whole
211 ical symptoms relative to wild-type mice and increased expression of S100A9 and S100A8 proteins in ke
214 hese results, transcriptome profiling showed increased expression of several direct p53 targets, redu
216 her investment into reproduction (including, increased expression of sexually dimorphic traits in mal
217 echanistically, loss of mTORC2 results in an increased expression of signature genes representing imm
218 betaR1, Col1alpha1, and cMyb expression, and increased expression of SMAD7, C/EBPalpha, and C/EBPdelt
220 CO2 activity was significantly elevated, and increased expression of SRC-2 with concomitant reduction
222 ormation and invasive activity, resulting in increased expression of stem-associated transcription fa
224 te subset of DNMT3A mutation carriers showed increased expression of T-cell stimulating immunoglobuli
225 on 1 upregulation, which subsequently causes increased expression of T-cell-attracting chemokines suc
226 l signature between health and disease, with increased expression of Th17-associated factors in perio
228 hoice-induced abstinence was associated with increased expression of the activity marker Fos in the O
229 -signaling mode (adipocytes and muscle) with increased expression of the ADAM10/17 metalloprotease th
230 ocrine signaling in adipocytes that promotes increased expression of the adipokine adiponectin and su
231 proliferation, which could be maintained by increased expression of the alternative amino acid trans
232 inflammatory cytokines IL10 and IL12P40, and increased expression of the angiogenic and neurotrophic
233 ion of channel transcripts revealed modestly increased expression of the ATXN1 co-repressor Capicua (
234 ation, was misregulated in male kidneys with increased expression of the canonical Wnt target lymphoi
235 ental infection by P. vranovensis results in increased expression of the cysteine synthases cysl-1 an
238 e endothelial activation molecule VCAM-1 but increased expression of the endothelial tight junction p
239 1/Kir5.1 and Nedd4-2 in the kidney exhibited increased expression of the epithelial sodium channel al
240 ecreased expression of the glutamatergic and increased expression of the GABA-ergic synaptic markers,
241 , it declines during ageing concomitant with increased expression of the gap junction protein Gja1.
242 and to localize promoter hypomethylation and increased expression of the growth factor Bmp7 to AgRP n
244 rough a positive feed-forward loop involving increased expression of the IL-2 receptor alpha-subunit
246 micronuclei formation, reduced Lamin B1, and increased expression of the immune regulators IL6 and IL
247 We also found that Stat3 inactivation led to increased expression of the inflammatory chemokines CCL5
248 tes and developed a thickened epidermis with increased expression of the inflammatory markers Keratin
249 ased growth of xenograft tumors in mice, and increased expression of the integrin subunits ITGA3 and
251 as risk variants in STX6 are associated with increased expression of the major transcripts in disease
252 ited the loss of mitochondrial integrity and increased expression of the microtubule-associated prote
253 d fission, decreased membrane potential, and increased expression of the mitochondria-specific protei
254 creases in MDSC accumulation correlated with increased expression of the myeloid cell lineage-specifi
255 hetic neurons: microbiota depletion leads to increased expression of the neuronal transcription facto
257 virus infection of the mosquito led to an in increased expression of the odorant binding protein 22 (
258 ibited interleukin 10 (IL-10) expression and increased expression of the p40 subunit shared by IL-12
259 g alveolar bone is resorbed when there is an increased expression of the pro-osteolytic factor termed
260 creased alpha-hemolysin (Hla) production but increased expression of the proteases SspAB and aureolys
261 confirmed increased expression of GDPD1 and increased expression of the retinal enhancer that enters
262 sing age as well as non-cell-autonomously by increased expression of the retinoic acid-degrading enzy
264 peripheral blood eosinophils accompanied by increased expression of the severe acute respiratory syn
267 ation carriers were further characterized by increased expression of the T-cell alpha receptor consta
268 Using an RNA-seq approach, we identified the increased expression of the tetraspanin family member, C
269 re, we show that pre-TCR signalling leads to increased expression of the transcriptional repressor Bc
270 by immunohistochemical validation identified increased expression of the TTSP family member, TMPRSS13
272 notably, the fusA1 mutant displayed greatly increased expression of the Type III secretion system (T
273 f the i4g1 x i4g2 plant growth phenotype and increased expression of the validated proteins to wild-t
274 otic resistance against tetracycline through increased expression of the xenobiotic transporters mexE
278 tactin, a nonhistone substrate of HDAC8, and increased expression of three fibrotic markers: alpha-sm
279 esult in increased serine degradation and in increased expression of threonine biosynthetic enzymes s
281 cell invasion, clinical studies demonstrated increased expression of TIMP-1 and its association with
283 NF-kappaB c-Rel and TonEBP essential for the increased expression of TonEBP-dependent osmoprotective
284 e to oxidative stress, which correlated with increased expression of tpx, a gene essential for defens
289 eptors (PRs) of diseased individuals display increased expression of two key glycolytic genes, sugges
290 Moreover, Th2 cells in presence of IL-3 show increased expression of type 2 effector cytokines, such
291 a transcriptional signature characterized by increased expression of type I and type II IFN-stimulate
292 combinant HMPVs and virion RNAs that induced increased expression of type I interferon, which was dep
293 t dermal endothelial cells in rosacea had an increased expression of VCAM1 and hypothesized that LL-3
296 fected astrocytes were inducible, leading to increased expression of viral proteins upon reactivation
297 amatergic receptor activity, consistent with increased expression of voltage-gated potassium channel
299 ly, Tbx3 (+/-) atrioventricular nodes showed increased expression of working myocardial gene programs